id sid tid token lemma pos cord-314679-lmfalzni 1 1 key key NN cord-314679-lmfalzni 1 2 : : : cord-314679-lmfalzni 2 1 cord-314679-lmfalzni cord-314679-lmfalzni NNP cord-314679-lmfalzni 2 2 authors author NNS cord-314679-lmfalzni 2 3 : : : cord-314679-lmfalzni 2 4 Sangith Sangith NNP cord-314679-lmfalzni 2 5 , , , cord-314679-lmfalzni 2 6 Nikhil Nikhil NNP cord-314679-lmfalzni 2 7 ; ; : cord-314679-lmfalzni 2 8 Diagnotek Diagnotek NNP cord-314679-lmfalzni 2 9 , , , cord-314679-lmfalzni 2 10 Xact Xact NNP cord-314679-lmfalzni 2 11 title title NN cord-314679-lmfalzni 2 12 : : : cord-314679-lmfalzni 2 13 Unique Unique NNP cord-314679-lmfalzni 2 14 Fibrinogen fibrinogen NN cord-314679-lmfalzni 2 15 - - HYPH cord-314679-lmfalzni 2 16 binding bind VBG cord-314679-lmfalzni 2 17 motifs motif NNS cord-314679-lmfalzni 2 18 in in IN cord-314679-lmfalzni 2 19 the the DT cord-314679-lmfalzni 2 20 Nucleocapsid Nucleocapsid NNP cord-314679-lmfalzni 2 21 Phosphoprotein Phosphoprotein NNP cord-314679-lmfalzni 2 22 of of IN cord-314679-lmfalzni 2 23 SARS SARS NNP cord-314679-lmfalzni 2 24 CoV-2 CoV-2 NNP cord-314679-lmfalzni 2 25 : : : cord-314679-lmfalzni 2 26 Potential potential JJ cord-314679-lmfalzni 2 27 Implications implication NNS cord-314679-lmfalzni 2 28 in in IN cord-314679-lmfalzni 2 29 Host Host NNP cord-314679-lmfalzni 2 30 - - HYPH cord-314679-lmfalzni 2 31 Pathogen Pathogen NNP cord-314679-lmfalzni 2 32 Interactions Interactions NNPS cord-314679-lmfalzni 2 33 date date NN cord-314679-lmfalzni 2 34 : : : cord-314679-lmfalzni 2 35 2020 2020 CD cord-314679-lmfalzni 2 36 - - HYPH cord-314679-lmfalzni 2 37 06 06 CD cord-314679-lmfalzni 2 38 - - HYPH cord-314679-lmfalzni 2 39 24 24 CD cord-314679-lmfalzni 2 40 journal journal NN cord-314679-lmfalzni 2 41 : : : cord-314679-lmfalzni 3 1 Med Med NNP cord-314679-lmfalzni 3 2 Hypotheses Hypotheses NNP cord-314679-lmfalzni 3 3 DOI DOI NNP cord-314679-lmfalzni 3 4 : : : cord-314679-lmfalzni 3 5 10.1016 10.1016 CD cord-314679-lmfalzni 3 6 / / SYM cord-314679-lmfalzni 3 7 j.mehy.2020.110030 j.mehy.2020.110030 NN cord-314679-lmfalzni 3 8 sha sha NNP cord-314679-lmfalzni 3 9 : : : cord-314679-lmfalzni 4 1 c772a9ce8690719eeb56aae2ce9a74702b61532b c772a9ce8690719eeb56aae2ce9a74702b61532b NNP cord-314679-lmfalzni 4 2 doc_id doc_id CD cord-314679-lmfalzni 4 3 : : : cord-314679-lmfalzni 4 4 314679 314679 CD cord-314679-lmfalzni 4 5 cord_uid cord_uid NNS cord-314679-lmfalzni 4 6 : : : cord-314679-lmfalzni 5 1 lmfalzni lmfalzni NNP cord-314679-lmfalzni 5 2 Novel Novel NNP cord-314679-lmfalzni 5 3 Coronavirus Coronavirus NNP cord-314679-lmfalzni 5 4 ( ( -LRB- cord-314679-lmfalzni 5 5 SARS SARS NNP cord-314679-lmfalzni 5 6 CoV-2 CoV-2 NNP cord-314679-lmfalzni 5 7 ) ) -RRB- cord-314679-lmfalzni 5 8 , , , cord-314679-lmfalzni 5 9 the the DT cord-314679-lmfalzni 5 10 etiological etiological JJ cord-314679-lmfalzni 5 11 agent agent NN cord-314679-lmfalzni 5 12 for for IN cord-314679-lmfalzni 5 13 the the DT cord-314679-lmfalzni 5 14 highly highly RB cord-314679-lmfalzni 5 15 contagious contagious JJ cord-314679-lmfalzni 5 16 Corona Corona NNP cord-314679-lmfalzni 5 17 virus virus NN cord-314679-lmfalzni 5 18 disease-2019 disease-2019 NNP cord-314679-lmfalzni 5 19 ( ( -LRB- cord-314679-lmfalzni 5 20 COVID-19 COVID-19 NNP cord-314679-lmfalzni 5 21 ) ) -RRB- cord-314679-lmfalzni 5 22 pandemic pandemic NN cord-314679-lmfalzni 5 23 has have VBZ cord-314679-lmfalzni 5 24 threatened threaten VBN cord-314679-lmfalzni 5 25 global global JJ cord-314679-lmfalzni 5 26 health health NN cord-314679-lmfalzni 5 27 and and CC cord-314679-lmfalzni 5 28 economy economy NN cord-314679-lmfalzni 5 29 infecting infect VBG cord-314679-lmfalzni 5 30 around around IN cord-314679-lmfalzni 5 31 5.8 5.8 CD cord-314679-lmfalzni 5 32 million million CD cord-314679-lmfalzni 5 33 people people NNS cord-314679-lmfalzni 5 34 and and CC cord-314679-lmfalzni 5 35 causing cause VBG cord-314679-lmfalzni 5 36 over over IN cord-314679-lmfalzni 5 37 359,200 359,200 CD cord-314679-lmfalzni 5 38 deaths death NNS cord-314679-lmfalzni 5 39 ( ( -LRB- cord-314679-lmfalzni 5 40 as as IN cord-314679-lmfalzni 5 41 of of IN cord-314679-lmfalzni 5 42 28(th 28(th CD cord-314679-lmfalzni 5 43 ) ) -RRB- cord-314679-lmfalzni 6 1 May May NNP cord-314679-lmfalzni 6 2 , , , cord-314679-lmfalzni 6 3 2020 2020 CD cord-314679-lmfalzni 6 4 , , , cord-314679-lmfalzni 6 5 https://www.worldometers.info/coronavirus/ https://www.worldometers.info/coronavirus/ NN cord-314679-lmfalzni 6 6 ) ) -RRB- cord-314679-lmfalzni 6 7 . . . cord-314679-lmfalzni 7 1 The the DT cord-314679-lmfalzni 7 2 clinical clinical JJ cord-314679-lmfalzni 7 3 manifestations manifestation NNS cord-314679-lmfalzni 7 4 of of IN cord-314679-lmfalzni 7 5 infected infected JJ cord-314679-lmfalzni 7 6 patients patient NNS cord-314679-lmfalzni 7 7 generally generally RB cord-314679-lmfalzni 7 8 range range VBP cord-314679-lmfalzni 7 9 from from IN cord-314679-lmfalzni 7 10 asymptomatic asymptomatic JJ cord-314679-lmfalzni 7 11 or or CC cord-314679-lmfalzni 7 12 mild mild JJ cord-314679-lmfalzni 7 13 to to IN cord-314679-lmfalzni 7 14 severe severe JJ cord-314679-lmfalzni 7 15 illness illness NN cord-314679-lmfalzni 7 16 , , , cord-314679-lmfalzni 7 17 or or CC cord-314679-lmfalzni 7 18 even even RB cord-314679-lmfalzni 7 19 death death NN cord-314679-lmfalzni 7 20 . . . cord-314679-lmfalzni 8 1 The the DT cord-314679-lmfalzni 8 2 ability ability NN cord-314679-lmfalzni 8 3 of of IN cord-314679-lmfalzni 8 4 the the DT cord-314679-lmfalzni 8 5 virus virus NN cord-314679-lmfalzni 8 6 to to TO cord-314679-lmfalzni 8 7 evade evade VB cord-314679-lmfalzni 8 8 the the DT cord-314679-lmfalzni 8 9 host host NN cord-314679-lmfalzni 8 10 immune immune JJ cord-314679-lmfalzni 8 11 response response NN cord-314679-lmfalzni 8 12 have have VBP cord-314679-lmfalzni 8 13 been be VBN cord-314679-lmfalzni 8 14 major major JJ cord-314679-lmfalzni 8 15 reasons reason NNS cord-314679-lmfalzni 8 16 for for IN cord-314679-lmfalzni 8 17 high high JJ cord-314679-lmfalzni 8 18 morbidity morbidity NN cord-314679-lmfalzni 8 19 and and CC cord-314679-lmfalzni 8 20 mortality mortality NN cord-314679-lmfalzni 8 21 . . . cord-314679-lmfalzni 9 1 One one CD cord-314679-lmfalzni 9 2 of of IN cord-314679-lmfalzni 9 3 the the DT cord-314679-lmfalzni 9 4 important important JJ cord-314679-lmfalzni 9 5 clinical clinical JJ cord-314679-lmfalzni 9 6 observations observation NNS cord-314679-lmfalzni 9 7 under under IN cord-314679-lmfalzni 9 8 conditions condition NNS cord-314679-lmfalzni 9 9 of of IN cord-314679-lmfalzni 9 10 critical critical JJ cord-314679-lmfalzni 9 11 illness illness NN cord-314679-lmfalzni 9 12 show show NN cord-314679-lmfalzni 9 13 increased increase VBD cord-314679-lmfalzni 9 14 risk risk NN cord-314679-lmfalzni 9 15 of of IN cord-314679-lmfalzni 9 16 developing develop VBG cord-314679-lmfalzni 9 17 disseminated disseminate VBN cord-314679-lmfalzni 9 18 intravascular intravascular JJ cord-314679-lmfalzni 9 19 coagulation coagulation NN cord-314679-lmfalzni 9 20 . . . cord-314679-lmfalzni 10 1 Molecular molecular JJ cord-314679-lmfalzni 10 2 mechanisms mechanism NNS cord-314679-lmfalzni 10 3 of of IN cord-314679-lmfalzni 10 4 how how WRB cord-314679-lmfalzni 10 5 SARS SARS NNP cord-314679-lmfalzni 10 6 CoV-2 CoV-2 NNP cord-314679-lmfalzni 10 7 induces induce VBZ cord-314679-lmfalzni 10 8 such such JJ cord-314679-lmfalzni 10 9 conditions condition NNS cord-314679-lmfalzni 10 10 still still RB cord-314679-lmfalzni 10 11 remain remain VBP cord-314679-lmfalzni 10 12 unclear unclear JJ cord-314679-lmfalzni 10 13 . . . cord-314679-lmfalzni 11 1 This this DT cord-314679-lmfalzni 11 2 report report NN cord-314679-lmfalzni 11 3 describes describe VBZ cord-314679-lmfalzni 11 4 the the DT cord-314679-lmfalzni 11 5 presence presence NN cord-314679-lmfalzni 11 6 of of IN cord-314679-lmfalzni 11 7 two two CD cord-314679-lmfalzni 11 8 unique unique JJ cord-314679-lmfalzni 11 9 motifs motif NNS cord-314679-lmfalzni 11 10 in in IN cord-314679-lmfalzni 11 11 the the DT cord-314679-lmfalzni 11 12 SARS SARS NNP cord-314679-lmfalzni 11 13 CoV-2 CoV-2 NNP cord-314679-lmfalzni 11 14 nucleocapsid nucleocapsid NN cord-314679-lmfalzni 11 15 phosphoprotein phosphoprotein NNP cord-314679-lmfalzni 11 16 ( ( -LRB- cord-314679-lmfalzni 11 17 N n CD cord-314679-lmfalzni 11 18 - - HYPH cord-314679-lmfalzni 11 19 protein protein NN cord-314679-lmfalzni 11 20 ) ) -RRB- cord-314679-lmfalzni 11 21 that that WDT cord-314679-lmfalzni 11 22 can can MD cord-314679-lmfalzni 11 23 potentially potentially RB cord-314679-lmfalzni 11 24 interact interact VB cord-314679-lmfalzni 11 25 with with IN cord-314679-lmfalzni 11 26 fibrinogen fibrinogen NN cord-314679-lmfalzni 11 27 and and CC cord-314679-lmfalzni 11 28 possibly possibly RB cord-314679-lmfalzni 11 29 prothrombin prothrombin NN cord-314679-lmfalzni 11 30 . . . cord-314679-lmfalzni 12 1 This this DT cord-314679-lmfalzni 12 2 is be VBZ cord-314679-lmfalzni 12 3 based base VBN cord-314679-lmfalzni 12 4 on on IN cord-314679-lmfalzni 12 5 an an DT cord-314679-lmfalzni 12 6 established establish VBN cord-314679-lmfalzni 12 7 function function NN cord-314679-lmfalzni 12 8 of of IN cord-314679-lmfalzni 12 9 secretory secretory JJ cord-314679-lmfalzni 12 10 proteins protein NNS cord-314679-lmfalzni 12 11 in in IN cord-314679-lmfalzni 12 12 Staphylococcus Staphylococcus NNP cord-314679-lmfalzni 12 13 aureus aureus NN cord-314679-lmfalzni 12 14 ( ( -LRB- cord-314679-lmfalzni 12 15 S. S. NNP cord-314679-lmfalzni 12 16 aureus)- aureus)- NNP cord-314679-lmfalzni 12 17 coagulase coagulase NN cord-314679-lmfalzni 12 18 , , , cord-314679-lmfalzni 12 19 Efb Efb NNP cord-314679-lmfalzni 12 20 ( ( -LRB- cord-314679-lmfalzni 12 21 Extracellular Extracellular NNP cord-314679-lmfalzni 12 22 fibrinogen fibrinogen NN cord-314679-lmfalzni 12 23 binding bind VBG cord-314679-lmfalzni 12 24 ) ) -RRB- cord-314679-lmfalzni 12 25 and and CC cord-314679-lmfalzni 12 26 vWBP vwbp JJ cord-314679-lmfalzni 12 27 ( ( -LRB- cord-314679-lmfalzni 12 28 von von NNP cord-314679-lmfalzni 12 29 Willebrand Willebrand NNP cord-314679-lmfalzni 12 30 factor factor NN cord-314679-lmfalzni 12 31 Binding Binding NNP cord-314679-lmfalzni 12 32 Protein Protein NNP cord-314679-lmfalzni 12 33 ) ) -RRB- cord-314679-lmfalzni 12 34 , , , cord-314679-lmfalzni 12 35 which which WDT cord-314679-lmfalzni 12 36 are be VBP cord-314679-lmfalzni 12 37 known know VBN cord-314679-lmfalzni 12 38 to to TO cord-314679-lmfalzni 12 39 regulate regulate VB cord-314679-lmfalzni 12 40 the the DT cord-314679-lmfalzni 12 41 blood blood NN cord-314679-lmfalzni 12 42 clotting clotting NN cord-314679-lmfalzni 12 43 cascade cascade NN cord-314679-lmfalzni 12 44 and and CC cord-314679-lmfalzni 12 45 the the DT cord-314679-lmfalzni 12 46 functions function NNS cord-314679-lmfalzni 12 47 of of IN cord-314679-lmfalzni 12 48 host host NN cord-314679-lmfalzni 12 49 immune immune JJ cord-314679-lmfalzni 12 50 response response NN cord-314679-lmfalzni 12 51 . . . cord-314679-lmfalzni 13 1 It -PRON- PRP cord-314679-lmfalzni 13 2 is be VBZ cord-314679-lmfalzni 13 3 hypothesized hypothesize VBN cord-314679-lmfalzni 13 4 that that IN cord-314679-lmfalzni 13 5 having have VBG cord-314679-lmfalzni 13 6 protein protein NN cord-314679-lmfalzni 13 7 interaction interaction NN cord-314679-lmfalzni 13 8 motifs motif NNS cord-314679-lmfalzni 13 9 that that WDT cord-314679-lmfalzni 13 10 are be VBP cord-314679-lmfalzni 13 11 homologous homologous JJ cord-314679-lmfalzni 13 12 to to IN cord-314679-lmfalzni 13 13 these these DT cord-314679-lmfalzni 13 14 S. S. NNP cord-314679-lmfalzni 13 15 aureus aureus NN cord-314679-lmfalzni 13 16 proteins protein NNS cord-314679-lmfalzni 13 17 , , , cord-314679-lmfalzni 13 18 the the DT cord-314679-lmfalzni 13 19 N n NN cord-314679-lmfalzni 13 20 - - HYPH cord-314679-lmfalzni 13 21 protein protein NN cord-314679-lmfalzni 13 22 of of IN cord-314679-lmfalzni 13 23 this this DT cord-314679-lmfalzni 13 24 virus virus NN cord-314679-lmfalzni 13 25 can can MD cord-314679-lmfalzni 13 26 mimic mimic VB cord-314679-lmfalzni 13 27 their -PRON- PRP$ cord-314679-lmfalzni 13 28 functions function NNS cord-314679-lmfalzni 13 29 , , , cord-314679-lmfalzni 13 30 which which WDT cord-314679-lmfalzni 13 31 may may MD cord-314679-lmfalzni 13 32 in in IN cord-314679-lmfalzni 13 33 turn turn NN cord-314679-lmfalzni 13 34 play play VB cord-314679-lmfalzni 13 35 a a DT cord-314679-lmfalzni 13 36 crucial crucial JJ cord-314679-lmfalzni 13 37 role role NN cord-314679-lmfalzni 13 38 in in IN cord-314679-lmfalzni 13 39 formation formation NN cord-314679-lmfalzni 13 40 of of IN cord-314679-lmfalzni 13 41 blood blood NN cord-314679-lmfalzni 13 42 clots clot NNS cord-314679-lmfalzni 13 43 in in IN cord-314679-lmfalzni 13 44 the the DT cord-314679-lmfalzni 13 45 host host NN cord-314679-lmfalzni 13 46 and and CC cord-314679-lmfalzni 13 47 help help VB cord-314679-lmfalzni 13 48 the the DT cord-314679-lmfalzni 13 49 virus virus NN cord-314679-lmfalzni 13 50 evade evade VB cord-314679-lmfalzni 13 51 host host NN cord-314679-lmfalzni 13 52 immune immune JJ cord-314679-lmfalzni 13 53 response response NN cord-314679-lmfalzni 13 54 . . . cord-314679-lmfalzni 14 1 However however RB cord-314679-lmfalzni 14 2 , , , cord-314679-lmfalzni 14 3 this this DT cord-314679-lmfalzni 14 4 hypothesis hypothesis NN cord-314679-lmfalzni 14 5 needs need VBZ cord-314679-lmfalzni 14 6 to to TO cord-314679-lmfalzni 14 7 be be VB cord-314679-lmfalzni 14 8 tested test VBN cord-314679-lmfalzni 14 9 in in IN cord-314679-lmfalzni 14 10 vitro vitro FW cord-314679-lmfalzni 14 11 . . . cord-314679-lmfalzni 15 1 Considering consider VBG cord-314679-lmfalzni 15 2 the the DT cord-314679-lmfalzni 15 3 overwhelming overwhelming JJ cord-314679-lmfalzni 15 4 increase increase NN cord-314679-lmfalzni 15 5 in in IN cord-314679-lmfalzni 15 6 the the DT cord-314679-lmfalzni 15 7 incidence incidence NN cord-314679-lmfalzni 15 8 of of IN cord-314679-lmfalzni 15 9 SARS SARS NNP cord-314679-lmfalzni 15 10 CoV-2 CoV-2 NNP cord-314679-lmfalzni 15 11 infection infection NN cord-314679-lmfalzni 15 12 globally globally RB cord-314679-lmfalzni 15 13 , , , cord-314679-lmfalzni 15 14 this this DT cord-314679-lmfalzni 15 15 information information NN cord-314679-lmfalzni 15 16 may may MD cord-314679-lmfalzni 15 17 be be VB cord-314679-lmfalzni 15 18 useful useful JJ cord-314679-lmfalzni 15 19 for for IN cord-314679-lmfalzni 15 20 further further JJ cord-314679-lmfalzni 15 21 investigation investigation NN cord-314679-lmfalzni 15 22 and and CC cord-314679-lmfalzni 15 23 could could MD cord-314679-lmfalzni 15 24 help help VB cord-314679-lmfalzni 15 25 in in IN cord-314679-lmfalzni 15 26 deducing deduce VBG cord-314679-lmfalzni 15 27 new new JJ cord-314679-lmfalzni 15 28 therapeutic therapeutic JJ cord-314679-lmfalzni 15 29 strategies strategy NNS cord-314679-lmfalzni 15 30 to to TO cord-314679-lmfalzni 15 31 combat combat VB cord-314679-lmfalzni 15 32 advanced advanced JJ cord-314679-lmfalzni 15 33 stages stage NNS cord-314679-lmfalzni 15 34 of of IN cord-314679-lmfalzni 15 35 this this DT cord-314679-lmfalzni 15 36 disease disease NN cord-314679-lmfalzni 15 37 . . . cord-314679-lmfalzni 16 1 signalling signal VBG cord-314679-lmfalzni 16 2 pathways pathway NNS cord-314679-lmfalzni 16 3 to to TO cord-314679-lmfalzni 16 4 escape escape VB cord-314679-lmfalzni 16 5 from from IN cord-314679-lmfalzni 16 6 the the DT cord-314679-lmfalzni 16 7 host host NN cord-314679-lmfalzni 16 8 immune immune JJ cord-314679-lmfalzni 16 9 response response NN cord-314679-lmfalzni 16 10 . . . cord-314679-lmfalzni 17 1 Fibrinogen fibrinogen NN cord-314679-lmfalzni 17 2 interaction interaction NN cord-314679-lmfalzni 17 3 with with IN cord-314679-lmfalzni 17 4 coagulase coagulase NNP cord-314679-lmfalzni 17 5 and and CC cord-314679-lmfalzni 17 6 Efb Efb NNP cord-314679-lmfalzni 17 7 of of IN cord-314679-lmfalzni 17 8 S. S. NNP cord-314679-lmfalzni 17 9 aureus aureus NN cord-314679-lmfalzni 17 10 is be VBZ cord-314679-lmfalzni 17 11 well well RB cord-314679-lmfalzni 17 12 established establish VBN cord-314679-lmfalzni 17 13 ( ( -LRB- cord-314679-lmfalzni 17 14 5 5 CD cord-314679-lmfalzni 17 15 , , , cord-314679-lmfalzni 17 16 7 7 CD cord-314679-lmfalzni 17 17 ) ) -RRB- cord-314679-lmfalzni 17 18 . . . cord-314679-lmfalzni 18 1 The the DT cord-314679-lmfalzni 18 2 role role NN cord-314679-lmfalzni 18 3 of of IN cord-314679-lmfalzni 18 4 the the DT cord-314679-lmfalzni 18 5 fibrinogen fibrinogen NN cord-314679-lmfalzni 18 6 - - HYPH cord-314679-lmfalzni 18 7 binding bind VBG cord-314679-lmfalzni 18 8 motif motif NN cord-314679-lmfalzni 18 9 of of IN cord-314679-lmfalzni 18 10 N n NN cord-314679-lmfalzni 18 11 - - HYPH cord-314679-lmfalzni 18 12 protein protein NN cord-314679-lmfalzni 18 13 in in IN cord-314679-lmfalzni 18 14 formation formation NN cord-314679-lmfalzni 18 15 of of IN cord-314679-lmfalzni 18 16 blood blood NN cord-314679-lmfalzni 18 17 clots clot NNS cord-314679-lmfalzni 18 18 and and CC cord-314679-lmfalzni 18 19 142 142 CD cord-314679-lmfalzni 18 20 mimicking mimicking NN cord-314679-lmfalzni 18 21 functions function NNS cord-314679-lmfalzni 18 22 of of IN cord-314679-lmfalzni 18 23 Efb Efb NNP cord-314679-lmfalzni 18 24 for for IN cord-314679-lmfalzni 18 25 pathogen pathogen NN cord-314679-lmfalzni 18 26 survival survival NN cord-314679-lmfalzni 18 27 in in IN cord-314679-lmfalzni 18 28 host host NN cord-314679-lmfalzni 18 29 will will MD cord-314679-lmfalzni 18 30 be be VB cord-314679-lmfalzni 18 31 investigated investigate VBN cord-314679-lmfalzni 18 32 . . . cord-314679-lmfalzni 19 1 The the DT cord-314679-lmfalzni 19 2 143 143 CD cord-314679-lmfalzni 19 3 affinity affinity NN cord-314679-lmfalzni 19 4 of of IN cord-314679-lmfalzni 19 5 the the DT cord-314679-lmfalzni 19 6 motif motif NN cord-314679-lmfalzni 19 7 towards towards IN cord-314679-lmfalzni 19 8 fibrinogen fibrinogen NN cord-314679-lmfalzni 19 9 will will MD cord-314679-lmfalzni 19 10 play play VB cord-314679-lmfalzni 19 11 a a DT cord-314679-lmfalzni 19 12 major major JJ cord-314679-lmfalzni 19 13 role role NN cord-314679-lmfalzni 19 14 in in IN cord-314679-lmfalzni 19 15 regulating regulate VBG cord-314679-lmfalzni 19 16 the the DT cord-314679-lmfalzni 19 17 functions function NNS cord-314679-lmfalzni 19 18 144 144 CD cord-314679-lmfalzni 19 19 Coagulation coagulation NN cord-314679-lmfalzni 19 20 disorders disorder NNS cord-314679-lmfalzni 19 21 in in IN cord-314679-lmfalzni 19 22 coronavirus coronavirus NN cord-314679-lmfalzni 19 23 infected infect VBN cord-314679-lmfalzni 19 24 patients patient NNS cord-314679-lmfalzni 19 25 Journal Journal NNP cord-314679-lmfalzni 19 26 of of IN cord-314679-lmfalzni 19 27 clinical clinical JJ cord-314679-lmfalzni 19 28 virology virology NN cord-314679-lmfalzni 19 29 : : : cord-314679-lmfalzni 19 30 the the DT cord-314679-lmfalzni 19 31 168 168 CD cord-314679-lmfalzni 19 32 official official JJ cord-314679-lmfalzni 19 33 publication publication NN cord-314679-lmfalzni 19 34 of of IN cord-314679-lmfalzni 19 35 the the DT cord-314679-lmfalzni 19 36 Pan Pan NNP cord-314679-lmfalzni 19 37 American American NNP cord-314679-lmfalzni 19 38 Society Society NNP cord-314679-lmfalzni 19 39 for for IN cord-314679-lmfalzni 19 40 Abnormal abnormal JJ cord-314679-lmfalzni 19 41 coagulation coagulation NN cord-314679-lmfalzni 19 42 parameters parameter NNS cord-314679-lmfalzni 19 43 are be VBP cord-314679-lmfalzni 19 44 associated associate VBN cord-314679-lmfalzni 19 45 with with IN cord-314679-lmfalzni 19 46 poor poor JJ cord-314679-lmfalzni 19 47 170 170 CD cord-314679-lmfalzni 19 48 prognosis prognosis NN cord-314679-lmfalzni 19 49 in in IN cord-314679-lmfalzni 19 50 patients patient NNS cord-314679-lmfalzni 19 51 with with IN cord-314679-lmfalzni 19 52 novel novel JJ cord-314679-lmfalzni 19 53 coronavirus coronavirus NN cord-314679-lmfalzni 19 54 pneumonia pneumonia NN cord-314679-lmfalzni 19 55 Immune immune JJ cord-314679-lmfalzni 19 56 responses response NNS cord-314679-lmfalzni 19 57 in in IN cord-314679-lmfalzni 19 58 COVID-19 COVID-19 NNP cord-314679-lmfalzni 19 59 and and CC cord-314679-lmfalzni 19 60 potential potential JJ cord-314679-lmfalzni 19 61 173 173 CD cord-314679-lmfalzni 19 62 vaccines vaccine NNS cord-314679-lmfalzni 19 63 : : : cord-314679-lmfalzni 19 64 Lessons lesson NNS cord-314679-lmfalzni 19 65 learned learn VBN cord-314679-lmfalzni 19 66 from from IN cord-314679-lmfalzni 19 67 SARS SARS NNP cord-314679-lmfalzni 19 68 and and CC cord-314679-lmfalzni 19 69 MERS MERS NNP cord-314679-lmfalzni 19 70 epidemic epidemic NN cord-314679-lmfalzni 20 1 The the DT cord-314679-lmfalzni 20 2 SARS SARS NNP cord-314679-lmfalzni 20 3 coronavirus coronavirus NN cord-314679-lmfalzni 20 4 176 176 CD cord-314679-lmfalzni 20 5 nucleocapsid nucleocapsid NN cord-314679-lmfalzni 20 6 protein protein NN cord-314679-lmfalzni 20 7 -- -- : cord-314679-lmfalzni 20 8 forms form NNS cord-314679-lmfalzni 20 9 and and CC cord-314679-lmfalzni 20 10 functions function VBZ cord-314679-lmfalzni 20 11 Staphylococcus Staphylococcus NNP cord-314679-lmfalzni 20 12 aureus aureu NNS cord-314679-lmfalzni 20 13 Have have VBP cord-314679-lmfalzni 20 14 a a DT cord-314679-lmfalzni 20 15 Common common JJ cord-314679-lmfalzni 20 16 Fibrinogen fibrinogen NN cord-314679-lmfalzni 20 17 Binding binding NN cord-314679-lmfalzni 20 18 Motif motif NN cord-314679-lmfalzni 20 19 Multiple multiple JJ cord-314679-lmfalzni 20 20 ligands ligand NNS cord-314679-lmfalzni 20 21 of of IN cord-314679-lmfalzni 20 22 von von NNP cord-314679-lmfalzni 20 23 Willebrand Willebrand NNP cord-314679-lmfalzni 20 24 factor factor NN cord-314679-lmfalzni 20 25 - - HYPH cord-314679-lmfalzni 20 26 binding bind VBG cord-314679-lmfalzni 20 27 181 181 CD cord-314679-lmfalzni 20 28 protein protein NN cord-314679-lmfalzni 20 29 ( ( -LRB- cord-314679-lmfalzni 20 30 vWbp vWbp NNP cord-314679-lmfalzni 20 31 ) ) -RRB- cord-314679-lmfalzni 20 32 promote promote VB cord-314679-lmfalzni 20 33 Staphylococcus Staphylococcus NNP cord-314679-lmfalzni 20 34 aureus aureus NN cord-314679-lmfalzni 20 35 clot clot NN cord-314679-lmfalzni 20 36 formation formation NN cord-314679-lmfalzni 20 37 in in IN cord-314679-lmfalzni 20 38 human human JJ cord-314679-lmfalzni 20 39 plasma plasma NN cord-314679-lmfalzni 20 40 Binding Binding NNP cord-314679-lmfalzni 20 41 of of IN cord-314679-lmfalzni 20 42 Efb Efb NNP cord-314679-lmfalzni 20 43 from from IN cord-314679-lmfalzni 20 44 Staphylococcus Staphylococcus NNP cord-314679-lmfalzni 20 45 184 184 CD cord-314679-lmfalzni 20 46 aureus aureus NN cord-314679-lmfalzni 20 47 to to IN cord-314679-lmfalzni 20 48 fibrinogen fibrinogen NN cord-314679-lmfalzni 20 49 blocks block NNS cord-314679-lmfalzni 20 50 neutrophil neutrophil NN cord-314679-lmfalzni 20 51 adherence adherence NN cord-314679-lmfalzni 20 52 Staphylococcus Staphylococcus NNP cord-314679-lmfalzni 20 53 aureus aureus NN cord-314679-lmfalzni 21 1 secretes secrete VBZ cord-314679-lmfalzni 21 2 coagulase coagulase NNP cord-314679-lmfalzni 21 3 187 187 CD cord-314679-lmfalzni 21 4 and and CC cord-314679-lmfalzni 21 5 von von NNP cord-314679-lmfalzni 21 6 Willebrand Willebrand NNP cord-314679-lmfalzni 21 7 factor factor NN cord-314679-lmfalzni 21 8 binding bind VBG cord-314679-lmfalzni 21 9 protein protein NN cord-314679-lmfalzni 21 10 to to TO cord-314679-lmfalzni 21 11 modify modify VB cord-314679-lmfalzni 21 12 the the DT cord-314679-lmfalzni 21 13 coagulation coagulation NN cord-314679-lmfalzni 21 14 cascade cascade NN cord-314679-lmfalzni 21 15 and and CC cord-314679-lmfalzni 21 16 establish establish VB cord-314679-lmfalzni 21 17 188 188 CD cord-314679-lmfalzni 21 18 host host NN cord-314679-lmfalzni 21 19 infections infection NNS cord-314679-lmfalzni 21 20 Fibrin(ogen)-alpha Fibrin(ogen)-alpha NNP cord-314679-lmfalzni 21 21 M m NN cord-314679-lmfalzni 21 22 beta beta NN cord-314679-lmfalzni 21 23 2 2 CD cord-314679-lmfalzni 21 24 interactions interaction NNS cord-314679-lmfalzni 21 25 regulate regulate VBP cord-314679-lmfalzni 21 26 leukocyte leukocyte NN cord-314679-lmfalzni 21 27 190 190 CD cord-314679-lmfalzni 21 28 function function NN cord-314679-lmfalzni 21 29 and and CC cord-314679-lmfalzni 21 30 innate innate JJ cord-314679-lmfalzni 21 31 immunity immunity NN cord-314679-lmfalzni 21 32 in in IN cord-314679-lmfalzni 21 33 vivo vivo NN cord-314679-lmfalzni 21 34 Leukocyte Leukocyte NNP cord-314679-lmfalzni 21 35 engagement engagement NN cord-314679-lmfalzni 21 36 of of IN cord-314679-lmfalzni 21 37 fibrin(ogen fibrin(ogen CD cord-314679-lmfalzni 21 38 ) ) -RRB- cord-314679-lmfalzni 22 1 via via IN cord-314679-lmfalzni 22 2 the the DT cord-314679-lmfalzni 22 3 integrin integrin NN cord-314679-lmfalzni 22 4 193 193 CD cord-314679-lmfalzni 22 5 receptor receptor NN cord-314679-lmfalzni 22 6 alphaMbeta2/ alphambeta2/ NN cord-314679-lmfalzni 23 1 Mac-1 Mac-1 NNP cord-314679-lmfalzni 23 2 is be VBZ cord-314679-lmfalzni 23 3 critical critical JJ cord-314679-lmfalzni 23 4 for for IN cord-314679-lmfalzni 23 5 host host JJ cord-314679-lmfalzni 23 6 inflammatory inflammatory JJ cord-314679-lmfalzni 23 7 response response NN cord-314679-lmfalzni 23 8 in in IN cord-314679-lmfalzni 23 9 vivo vivo NNP cord-314679-lmfalzni 23 10 Phagocytosis Phagocytosis NNP cord-314679-lmfalzni 23 11 escape escape VBP cord-314679-lmfalzni 23 12 by by IN cord-314679-lmfalzni 23 13 a a DT cord-314679-lmfalzni 23 14 Staphylococcus Staphylococcus NNP cord-314679-lmfalzni 23 15 aureus aureus NN cord-314679-lmfalzni 23 16 196 196 CD cord-314679-lmfalzni 23 17 protein protein NN cord-314679-lmfalzni 23 18 that that WDT cord-314679-lmfalzni 23 19 connects connect VBZ cord-314679-lmfalzni 23 20 complement complement NN cord-314679-lmfalzni 23 21 and and CC cord-314679-lmfalzni 23 22 coagulation coagulation NN cord-314679-lmfalzni 23 23 proteins protein NNS cord-314679-lmfalzni 23 24 at at IN cord-314679-lmfalzni 23 25 the the DT cord-314679-lmfalzni 23 26 bacterial bacterial JJ cord-314679-lmfalzni 23 27 surface surface NN cord-314679-lmfalzni 23 28 Coronaviruses Coronaviruses NNPS cord-314679-lmfalzni 23 29 hijack hijack VBP cord-314679-lmfalzni 23 30 the the DT cord-314679-lmfalzni 23 31 complement complement JJ cord-314679-lmfalzni 23 32 system system NN cord-314679-lmfalzni 23 33 of of IN cord-314679-lmfalzni 23 34 fibrinogen fibrinogen NN cord-314679-lmfalzni 23 35 and and CC cord-314679-lmfalzni 23 36 in in IN cord-314679-lmfalzni 23 37 turn turn NN cord-314679-lmfalzni 23 38 the the DT cord-314679-lmfalzni 23 39 host host NN cord-314679-lmfalzni 23 40 immune immune JJ cord-314679-lmfalzni 23 41 system system NN cord-314679-lmfalzni 23 42 . . . cord-314679-lmfalzni 24 1 At at IN cord-314679-lmfalzni 24 2 this this DT cord-314679-lmfalzni 24 3 juncture juncture NN cord-314679-lmfalzni 24 4 , , , cord-314679-lmfalzni 24 5 the the DT cord-314679-lmfalzni 24 6 knowledge knowledge NN cord-314679-lmfalzni 24 7 of of IN cord-314679-lmfalzni 24 8 145 145 CD cord-314679-lmfalzni 24 9 existence existence NN cord-314679-lmfalzni 24 10 of of IN cord-314679-lmfalzni 24 11 such such PDT cord-314679-lmfalzni 24 12 a a DT cord-314679-lmfalzni 24 13 motif motif NN cord-314679-lmfalzni 24 14 will will MD cord-314679-lmfalzni 24 15 help help VB cord-314679-lmfalzni 24 16 investigators investigator NNS cord-314679-lmfalzni 24 17 to to TO cord-314679-lmfalzni 24 18 further further JJ cord-314679-lmfalzni 24 19 probe probe VB cord-314679-lmfalzni 24 20 and and CC cord-314679-lmfalzni 24 21 establish establish VB cord-314679-lmfalzni 24 22 its -PRON- PRP$ cord-314679-lmfalzni 24 23 role role NN cord-314679-lmfalzni 24 24 _SP