id	sid	tid	token	lemma	pos
cord-308279-gsk4qel5	1	1	key	key	JJ
cord-308279-gsk4qel5	1	2	:	:	:
cord-308279-gsk4qel5	1	3	cord-308279-gsk4qel5	cord-308279-gsk4qel5	NN
cord-308279-gsk4qel5	1	4	authors	author	NNS
cord-308279-gsk4qel5	1	5	:	:	:
cord-308279-gsk4qel5	1	6	Suzuki	Suzuki	NNP
cord-308279-gsk4qel5	1	7	,	,	,
cord-308279-gsk4qel5	1	8	Yuichiro	Yuichiro	NNP
cord-308279-gsk4qel5	1	9	J.	J.	NNP
cord-308279-gsk4qel5	1	10	title	title	NN
cord-308279-gsk4qel5	1	11	:	:	:
cord-308279-gsk4qel5	2	1	The	the	DT
cord-308279-gsk4qel5	2	2	viral	viral	JJ
cord-308279-gsk4qel5	2	3	protein	protein	NN
cord-308279-gsk4qel5	2	4	fragment	fragment	NN
cord-308279-gsk4qel5	2	5	theory	theory	NN
cord-308279-gsk4qel5	2	6	of	of	IN
cord-308279-gsk4qel5	2	7	COVID-19	covid-19	JJ
cord-308279-gsk4qel5	2	8	pathogenesis	pathogenesis	NN
cord-308279-gsk4qel5	2	9	date	date	NN
cord-308279-gsk4qel5	2	10	:	:	:
cord-308279-gsk4qel5	2	11	2020	2020	CD
cord-308279-gsk4qel5	2	12	-	-	HYPH
cord-308279-gsk4qel5	2	13	09	09	CD
cord-308279-gsk4qel5	2	14	-	-	SYM
cord-308279-gsk4qel5	2	15	11	11	CD
cord-308279-gsk4qel5	2	16	journal	journal	NN
cord-308279-gsk4qel5	2	17	:	:	:
cord-308279-gsk4qel5	3	1	Med	Med	NNP
cord-308279-gsk4qel5	3	2	Hypotheses	Hypotheses	NNP
cord-308279-gsk4qel5	3	3	DOI	DOI	NNP
cord-308279-gsk4qel5	3	4	:	:	:
cord-308279-gsk4qel5	3	5	10.1016	10.1016	CD
cord-308279-gsk4qel5	3	6	/	/	SYM
cord-308279-gsk4qel5	3	7	j.mehy.2020.110267	j.mehy.2020.110267	VBD
cord-308279-gsk4qel5	3	8	sha	sha	NNP
cord-308279-gsk4qel5	3	9	:	:	:
cord-308279-gsk4qel5	3	10	f3974360cf3e716539c9836a7fbaa15d4dfc0f39	f3974360cf3e716539c9836a7fbaa15d4dfc0f39	NNP
cord-308279-gsk4qel5	3	11	doc_id	doc_id	CD
cord-308279-gsk4qel5	3	12	:	:	:
cord-308279-gsk4qel5	3	13	308279	308279	CD
cord-308279-gsk4qel5	3	14	cord_uid	cord_uid	NNS
cord-308279-gsk4qel5	3	15	:	:	:
cord-308279-gsk4qel5	3	16	gsk4qel5	gsk4qel5	NNP
cord-308279-gsk4qel5	3	17	Severe	severe	JJ
cord-308279-gsk4qel5	3	18	acute	acute	JJ
cord-308279-gsk4qel5	3	19	respiratory	respiratory	JJ
cord-308279-gsk4qel5	3	20	syndrome	syndrome	NN
cord-308279-gsk4qel5	3	21	coronavirus	coronavirus	NN
cord-308279-gsk4qel5	3	22	2	2	CD
cord-308279-gsk4qel5	4	1	(	(	-LRB-
cord-308279-gsk4qel5	4	2	SARS	SARS	NNP
cord-308279-gsk4qel5	4	3	-	-	HYPH
cord-308279-gsk4qel5	4	4	CoV-2	CoV-2	NNP
cord-308279-gsk4qel5	4	5	)	)	-RRB-
cord-308279-gsk4qel5	4	6	is	be	VBZ
cord-308279-gsk4qel5	4	7	causing	cause	VBG
cord-308279-gsk4qel5	4	8	the	the	DT
cord-308279-gsk4qel5	4	9	current	current	JJ
cord-308279-gsk4qel5	4	10	pandemic	pandemic	NN
cord-308279-gsk4qel5	4	11	of	of	IN
cord-308279-gsk4qel5	4	12	coronavirus	coronavirus	NN
cord-308279-gsk4qel5	4	13	disease	disease	NN
cord-308279-gsk4qel5	4	14	2019	2019	CD
cord-308279-gsk4qel5	4	15	(	(	-LRB-
cord-308279-gsk4qel5	4	16	COVID-19	COVID-19	NNP
cord-308279-gsk4qel5	4	17	)	)	-RRB-
cord-308279-gsk4qel5	4	18	that	that	WDT
cord-308279-gsk4qel5	4	19	have	have	VBP
cord-308279-gsk4qel5	4	20	killed	kill	VBN
cord-308279-gsk4qel5	4	21	nearly	nearly	RB
cord-308279-gsk4qel5	4	22	one	one	CD
cord-308279-gsk4qel5	4	23	million	million	CD
cord-308279-gsk4qel5	4	24	people	people	NNS
cord-308279-gsk4qel5	4	25	so	so	RB
cord-308279-gsk4qel5	4	26	far	far	RB
cord-308279-gsk4qel5	4	27	.	.	.
cord-308279-gsk4qel5	5	1	While	while	IN
cord-308279-gsk4qel5	5	2	this	this	DT
cord-308279-gsk4qel5	5	3	appears	appear	VBZ
cord-308279-gsk4qel5	5	4	to	to	TO
cord-308279-gsk4qel5	5	5	be	be	VB
cord-308279-gsk4qel5	5	6	a	a	DT
cord-308279-gsk4qel5	5	7	respiratory	respiratory	JJ
cord-308279-gsk4qel5	5	8	virus	virus	NN
cord-308279-gsk4qel5	5	9	,	,	,
cord-308279-gsk4qel5	5	10	surprisingly	surprisingly	RB
cord-308279-gsk4qel5	5	11	,	,	,
cord-308279-gsk4qel5	5	12	it	-PRON-	PRP
cord-308279-gsk4qel5	5	13	has	have	VBZ
cord-308279-gsk4qel5	5	14	been	be	VBN
cord-308279-gsk4qel5	5	15	recognized	recognize	VBN
cord-308279-gsk4qel5	5	16	that	that	IN
cord-308279-gsk4qel5	5	17	patients	patient	NNS
cord-308279-gsk4qel5	5	18	with	with	IN
cord-308279-gsk4qel5	5	19	cardiovascular	cardiovascular	JJ
cord-308279-gsk4qel5	5	20	disease	disease	NN
cord-308279-gsk4qel5	5	21	are	be	VBP
cord-308279-gsk4qel5	5	22	likely	likely	JJ
cord-308279-gsk4qel5	5	23	to	to	TO
cord-308279-gsk4qel5	5	24	be	be	VB
cord-308279-gsk4qel5	5	25	affected	affect	VBN
cord-308279-gsk4qel5	5	26	severely	severely	RB
cord-308279-gsk4qel5	5	27	and	and	CC
cord-308279-gsk4qel5	5	28	die	die	VB
cord-308279-gsk4qel5	5	29	of	of	IN
cord-308279-gsk4qel5	5	30	COVID-19	COVID-19	NNP
cord-308279-gsk4qel5	5	31	.	.	.
cord-308279-gsk4qel5	6	1	This	this	DT
cord-308279-gsk4qel5	6	2	phenomenon	phenomenon	NN
cord-308279-gsk4qel5	6	3	can	can	MD
cord-308279-gsk4qel5	6	4	not	not	RB
cord-308279-gsk4qel5	6	5	be	be	VB
cord-308279-gsk4qel5	6	6	explained	explain	VBN
cord-308279-gsk4qel5	6	7	by	by	IN
cord-308279-gsk4qel5	6	8	the	the	DT
cord-308279-gsk4qel5	6	9	generally	generally	RB
cord-308279-gsk4qel5	6	10	accepted	accept	VBN
cord-308279-gsk4qel5	6	11	logic	logic	NN
cord-308279-gsk4qel5	6	12	that	that	IN
cord-308279-gsk4qel5	6	13	the	the	DT
cord-308279-gsk4qel5	6	14	SARS	SARS	NNP
cord-308279-gsk4qel5	6	15	-	-	HYPH
cord-308279-gsk4qel5	6	16	CoV-2	CoV-2	NNP
cord-308279-gsk4qel5	6	17	infection	infection	NN
cord-308279-gsk4qel5	6	18	/	/	SYM
cord-308279-gsk4qel5	6	19	replication	replication	NN
cord-308279-gsk4qel5	6	20	is	be	VBZ
cord-308279-gsk4qel5	6	21	the	the	DT
cord-308279-gsk4qel5	6	22	sole	sole	JJ
cord-308279-gsk4qel5	6	23	determinant	determinant	NN
cord-308279-gsk4qel5	6	24	of	of	IN
cord-308279-gsk4qel5	6	25	the	the	DT
cord-308279-gsk4qel5	6	26	actions	action	NNS
cord-308279-gsk4qel5	6	27	of	of	IN
cord-308279-gsk4qel5	6	28	the	the	DT
cord-308279-gsk4qel5	6	29	virus	virus	NN
cord-308279-gsk4qel5	6	30	to	to	TO
cord-308279-gsk4qel5	6	31	define	define	VB
cord-308279-gsk4qel5	6	32	the	the	DT
cord-308279-gsk4qel5	6	33	fate	fate	NN
cord-308279-gsk4qel5	6	34	of	of	IN
cord-308279-gsk4qel5	6	35	host	host	NN
cord-308279-gsk4qel5	6	36	cells	cell	NNS
cord-308279-gsk4qel5	6	37	.	.	.
cord-308279-gsk4qel5	7	1	I	-PRON-	PRP
cord-308279-gsk4qel5	7	2	herein	herein	RB
cord-308279-gsk4qel5	7	3	propose	propose	VBP
cord-308279-gsk4qel5	7	4	the	the	DT
cord-308279-gsk4qel5	7	5	viral	viral	JJ
cord-308279-gsk4qel5	7	6	protein	protein	NN
cord-308279-gsk4qel5	7	7	fragment	fragment	NN
cord-308279-gsk4qel5	7	8	theory	theory	NN
cord-308279-gsk4qel5	7	9	of	of	IN
cord-308279-gsk4qel5	7	10	COVID-19	covid-19	JJ
cord-308279-gsk4qel5	7	11	pathogenesis	pathogenesis	NN
cord-308279-gsk4qel5	7	12	based	base	VBN
cord-308279-gsk4qel5	7	13	on	on	IN
cord-308279-gsk4qel5	7	14	my	-PRON-	PRP$
cord-308279-gsk4qel5	7	15	observations	observation	NNS
cord-308279-gsk4qel5	7	16	in	in	IN
cord-308279-gsk4qel5	7	17	cultured	cultured	JJ
cord-308279-gsk4qel5	7	18	human	human	JJ
cord-308279-gsk4qel5	7	19	vascular	vascular	JJ
cord-308279-gsk4qel5	7	20	cells	cell	NNS
cord-308279-gsk4qel5	7	21	that	that	IN
cord-308279-gsk4qel5	7	22	SARS	SARS	NNP
cord-308279-gsk4qel5	7	23	-	-	HYPH
cord-308279-gsk4qel5	7	24	CoV-2	CoV-2	NNP
cord-308279-gsk4qel5	7	25	spike	spike	NN
cord-308279-gsk4qel5	7	26	protein	protein	NN
cord-308279-gsk4qel5	7	27	can	can	MD
cord-308279-gsk4qel5	7	28	activate	activate	VB
cord-308279-gsk4qel5	7	29	cell	cell	NN
cord-308279-gsk4qel5	7	30	signaling	signal	VBG
cord-308279-gsk4qel5	7	31	events	event	NNS
cord-308279-gsk4qel5	7	32	without	without	IN
cord-308279-gsk4qel5	7	33	the	the	DT
cord-308279-gsk4qel5	7	34	rest	rest	NN
cord-308279-gsk4qel5	7	35	of	of	IN
cord-308279-gsk4qel5	7	36	the	the	DT
cord-308279-gsk4qel5	7	37	viral	viral	JJ
cord-308279-gsk4qel5	7	38	components	component	NNS
cord-308279-gsk4qel5	7	39	.	.	.
cord-308279-gsk4qel5	8	1	It	-PRON-	PRP
cord-308279-gsk4qel5	8	2	is	be	VBZ
cord-308279-gsk4qel5	8	3	generally	generally	RB
cord-308279-gsk4qel5	8	4	thought	think	VBN
cord-308279-gsk4qel5	8	5	that	that	IN
cord-308279-gsk4qel5	8	6	SARS	SARS	NNP
cord-308279-gsk4qel5	8	7	-	-	HYPH
cord-308279-gsk4qel5	8	8	CoV-2	CoV-2	NNP
cord-308279-gsk4qel5	8	9	and	and	CC
cord-308279-gsk4qel5	8	10	other	other	JJ
cord-308279-gsk4qel5	8	11	single	single	RB
cord-308279-gsk4qel5	8	12	-	-	HYPH
cord-308279-gsk4qel5	8	13	stranded	strand	VBN
cord-308279-gsk4qel5	8	14	RNA	RNA	NNP
cord-308279-gsk4qel5	8	15	viruses	virus	NNS
cord-308279-gsk4qel5	8	16	attach	attach	VBP
cord-308279-gsk4qel5	8	17	to	to	IN
cord-308279-gsk4qel5	8	18	the	the	DT
cord-308279-gsk4qel5	8	19	host	host	NN
cord-308279-gsk4qel5	8	20	cells	cell	NNS
cord-308279-gsk4qel5	8	21	through	through	IN
cord-308279-gsk4qel5	8	22	the	the	DT
cord-308279-gsk4qel5	8	23	interactions	interaction	NNS
cord-308279-gsk4qel5	8	24	between	between	IN
cord-308279-gsk4qel5	8	25	surface	surface	NN
cord-308279-gsk4qel5	8	26	proteins	protein	NNS
cord-308279-gsk4qel5	8	27	of	of	IN
cord-308279-gsk4qel5	8	28	the	the	DT
cord-308279-gsk4qel5	8	29	viral	viral	JJ
cord-308279-gsk4qel5	8	30	capsid	capsid	NN
cord-308279-gsk4qel5	8	31	and	and	CC
cord-308279-gsk4qel5	8	32	the	the	DT
cord-308279-gsk4qel5	8	33	host	host	NN
cord-308279-gsk4qel5	8	34	cell	cell	NN
cord-308279-gsk4qel5	8	35	receptors	receptor	NNS
cord-308279-gsk4qel5	8	36	;	;	:
cord-308279-gsk4qel5	8	37	the	the	DT
cord-308279-gsk4qel5	8	38	fusion	fusion	NN
cord-308279-gsk4qel5	8	39	and	and	CC
cord-308279-gsk4qel5	8	40	the	the	DT
cord-308279-gsk4qel5	8	41	entry	entry	NN
cord-308279-gsk4qel5	8	42	of	of	IN
cord-308279-gsk4qel5	8	43	the	the	DT
cord-308279-gsk4qel5	8	44	viral	viral	JJ
cord-308279-gsk4qel5	8	45	components	component	NNS
cord-308279-gsk4qel5	8	46	,	,	,
cord-308279-gsk4qel5	8	47	resulting	result	VBG
cord-308279-gsk4qel5	8	48	in	in	IN
cord-308279-gsk4qel5	8	49	the	the	DT
cord-308279-gsk4qel5	8	50	replication	replication	NN
cord-308279-gsk4qel5	8	51	of	of	IN
cord-308279-gsk4qel5	8	52	the	the	DT
cord-308279-gsk4qel5	8	53	viruses	virus	NNS
cord-308279-gsk4qel5	8	54	;	;	:
cord-308279-gsk4qel5	8	55	and	and	CC
cord-308279-gsk4qel5	8	56	the	the	DT
cord-308279-gsk4qel5	8	57	host	host	NN
cord-308279-gsk4qel5	8	58	cell	cell	NN
cord-308279-gsk4qel5	8	59	responses	response	NNS
cord-308279-gsk4qel5	8	60	are	be	VBP
cord-308279-gsk4qel5	8	61	the	the	DT
cord-308279-gsk4qel5	8	62	consequence	consequence	NN
cord-308279-gsk4qel5	8	63	of	of	IN
cord-308279-gsk4qel5	8	64	these	these	DT
cord-308279-gsk4qel5	8	65	events	event	NNS
cord-308279-gsk4qel5	8	66	.	.	.
cord-308279-gsk4qel5	9	1	I	-PRON-	PRP
cord-308279-gsk4qel5	9	2	hypothesize	hypothesize	VBP
cord-308279-gsk4qel5	9	3	that	that	IN
cord-308279-gsk4qel5	9	4	,	,	,
cord-308279-gsk4qel5	9	5	as	as	IN
cord-308279-gsk4qel5	9	6	humans	human	NNS
cord-308279-gsk4qel5	9	7	are	be	VBP
cord-308279-gsk4qel5	9	8	infected	infect	VBN
cord-308279-gsk4qel5	9	9	with	with	IN
cord-308279-gsk4qel5	9	10	SARS	SARS	NNP
cord-308279-gsk4qel5	9	11	-	-	HYPH
cord-308279-gsk4qel5	9	12	CoV-2	CoV-2	NNP
cord-308279-gsk4qel5	9	13	,	,	,
cord-308279-gsk4qel5	9	14	the	the	DT
cord-308279-gsk4qel5	9	15	virus	virus	NN
cord-308279-gsk4qel5	9	16	releases	release	VBZ
cord-308279-gsk4qel5	9	17	a	a	DT
cord-308279-gsk4qel5	9	18	fragment	fragment	NN
cord-308279-gsk4qel5	9	19	of	of	IN
cord-308279-gsk4qel5	9	20	the	the	DT
cord-308279-gsk4qel5	9	21	spike	spike	NN
cord-308279-gsk4qel5	9	22	protein	protein	NN
cord-308279-gsk4qel5	9	23	that	that	WDT
cord-308279-gsk4qel5	9	24	can	can	MD
cord-308279-gsk4qel5	9	25	target	target	VB
cord-308279-gsk4qel5	9	26	host	host	NN
cord-308279-gsk4qel5	9	27	cells	cell	NNS
cord-308279-gsk4qel5	9	28	for	for	IN
cord-308279-gsk4qel5	9	29	eliciting	elicit	VBG
cord-308279-gsk4qel5	9	30	cell	cell	NN
cord-308279-gsk4qel5	9	31	signaling	signal	VBG
cord-308279-gsk4qel5	9	32	without	without	IN
cord-308279-gsk4qel5	9	33	the	the	DT
cord-308279-gsk4qel5	9	34	rest	rest	NN
cord-308279-gsk4qel5	9	35	of	of	IN
cord-308279-gsk4qel5	9	36	the	the	DT
cord-308279-gsk4qel5	9	37	viral	viral	JJ
cord-308279-gsk4qel5	9	38	components	component	NNS
cord-308279-gsk4qel5	9	39	.	.	.
cord-308279-gsk4qel5	10	1	Thus	thus	RB
cord-308279-gsk4qel5	10	2	,	,	,
cord-308279-gsk4qel5	10	3	COVID-19	covid-19	JJ
cord-308279-gsk4qel5	10	4	patients	patient	NNS
cord-308279-gsk4qel5	10	5	are	be	VBP
cord-308279-gsk4qel5	10	6	subjected	subject	VBN
cord-308279-gsk4qel5	10	7	to	to	IN
cord-308279-gsk4qel5	10	8	the	the	DT
cord-308279-gsk4qel5	10	9	intact	intact	JJ
cord-308279-gsk4qel5	10	10	virus	virus	NN
cord-308279-gsk4qel5	10	11	infecting	infect	VBG
cord-308279-gsk4qel5	10	12	the	the	DT
cord-308279-gsk4qel5	10	13	host	host	NN
cord-308279-gsk4qel5	10	14	cells	cell	NNS
cord-308279-gsk4qel5	10	15	for	for	IN
cord-308279-gsk4qel5	10	16	the	the	DT
cord-308279-gsk4qel5	10	17	replication	replication	NN
cord-308279-gsk4qel5	10	18	and	and	CC
cord-308279-gsk4qel5	10	19	the	the	DT
cord-308279-gsk4qel5	10	20	amplification	amplification	NN
cord-308279-gsk4qel5	10	21	as	as	RB
cord-308279-gsk4qel5	10	22	well	well	RB
cord-308279-gsk4qel5	10	23	as	as	IN
cord-308279-gsk4qel5	10	24	the	the	DT
cord-308279-gsk4qel5	10	25	spike	spike	NN
cord-308279-gsk4qel5	10	26	protein	protein	NN
cord-308279-gsk4qel5	10	27	fragment	fragment	NN
cord-308279-gsk4qel5	10	28	that	that	WDT
cord-308279-gsk4qel5	10	29	are	be	VBP
cord-308279-gsk4qel5	10	30	capable	capable	JJ
cord-308279-gsk4qel5	10	31	of	of	IN
cord-308279-gsk4qel5	10	32	affecting	affect	VBG
cord-308279-gsk4qel5	10	33	the	the	DT
cord-308279-gsk4qel5	10	34	host	host	NN
cord-308279-gsk4qel5	10	35	cells	cell	NNS
cord-308279-gsk4qel5	10	36	.	.	.
cord-308279-gsk4qel5	11	1	I	-PRON-	PRP
cord-308279-gsk4qel5	11	2	propose	propose	VBP
cord-308279-gsk4qel5	11	3	that	that	IN
cord-308279-gsk4qel5	11	4	cell	cell	NN
cord-308279-gsk4qel5	11	5	signaling	signal	VBG
cord-308279-gsk4qel5	11	6	elicited	elicit	VBN
cord-308279-gsk4qel5	11	7	by	by	IN
cord-308279-gsk4qel5	11	8	the	the	DT
cord-308279-gsk4qel5	11	9	spike	spike	NN
cord-308279-gsk4qel5	11	10	protein	protein	NN
cord-308279-gsk4qel5	11	11	fragment	fragment	NN
cord-308279-gsk4qel5	11	12	that	that	WDT
cord-308279-gsk4qel5	11	13	occurs	occur	VBZ
cord-308279-gsk4qel5	11	14	on	on	IN
cord-308279-gsk4qel5	11	15	cardiovascular	cardiovascular	JJ
cord-308279-gsk4qel5	11	16	cells	cell	NNS
cord-308279-gsk4qel5	11	17	would	would	MD
cord-308279-gsk4qel5	11	18	predispose	predispose	VB
cord-308279-gsk4qel5	11	19	infected	infected	JJ
cord-308279-gsk4qel5	11	20	individuals	individual	NNS
cord-308279-gsk4qel5	11	21	to	to	TO
cord-308279-gsk4qel5	11	22	develop	develop	VB
cord-308279-gsk4qel5	11	23	complications	complication	NNS
cord-308279-gsk4qel5	11	24	that	that	WDT
cord-308279-gsk4qel5	11	25	are	be	VBP
cord-308279-gsk4qel5	11	26	seen	see	VBN
cord-308279-gsk4qel5	11	27	in	in	IN
cord-308279-gsk4qel5	11	28	severe	severe	JJ
cord-308279-gsk4qel5	11	29	and	and	CC
cord-308279-gsk4qel5	11	30	fatal	fatal	JJ
cord-308279-gsk4qel5	11	31	COVID-19	covid-19	CD
cord-308279-gsk4qel5	11	32	conditions	condition	NNS
cord-308279-gsk4qel5	11	33	.	.	.
cord-308279-gsk4qel5	12	1	If	if	IN
cord-308279-gsk4qel5	12	2	this	this	DT
cord-308279-gsk4qel5	12	3	hypothesis	hypothesis	NN
cord-308279-gsk4qel5	12	4	is	be	VBZ
cord-308279-gsk4qel5	12	5	correct	correct	JJ
cord-308279-gsk4qel5	12	6	,	,	,
cord-308279-gsk4qel5	12	7	then	then	RB
cord-308279-gsk4qel5	12	8	the	the	DT
cord-308279-gsk4qel5	12	9	strategies	strategy	NNS
cord-308279-gsk4qel5	12	10	to	to	TO
cord-308279-gsk4qel5	12	11	treat	treat	VB
cord-308279-gsk4qel5	12	12	COVID-19	COVID-19	NNP
cord-308279-gsk4qel5	12	13	should	should	MD
cord-308279-gsk4qel5	12	14	include	include	VB
cord-308279-gsk4qel5	12	15	,	,	,
cord-308279-gsk4qel5	12	16	in	in	IN
cord-308279-gsk4qel5	12	17	addition	addition	NN
cord-308279-gsk4qel5	12	18	to	to	IN
cord-308279-gsk4qel5	12	19	giving	give	VBG
cord-308279-gsk4qel5	12	20	agents	agent	NNS
cord-308279-gsk4qel5	12	21	that	that	WDT
cord-308279-gsk4qel5	12	22	inhibit	inhibit	VBP
cord-308279-gsk4qel5	12	23	the	the	DT
cord-308279-gsk4qel5	12	24	viral	viral	JJ
cord-308279-gsk4qel5	12	25	replication	replication	NN
cord-308279-gsk4qel5	12	26	,	,	,
cord-308279-gsk4qel5	12	27	therapeutics	therapeutic	NNS
cord-308279-gsk4qel5	12	28	that	that	WDT
cord-308279-gsk4qel5	12	29	inhibit	inhibit	VBP
cord-308279-gsk4qel5	12	30	the	the	DT
cord-308279-gsk4qel5	12	31	virus	virus	NN
cord-308279-gsk4qel5	12	32	fragment	fragment	NN
cord-308279-gsk4qel5	12	33	-	-	HYPH
cord-308279-gsk4qel5	12	34	mediated	mediate	VBN
cord-308279-gsk4qel5	12	35	cell	cell	NN
cord-308279-gsk4qel5	12	36	signaling	signal	VBG
cord-308279-gsk4qel5	12	37	on	on	IN
cord-308279-gsk4qel5	12	38	cardiovascular	cardiovascular	JJ
cord-308279-gsk4qel5	12	39	cells	cell	NNS
cord-308279-gsk4qel5	12	40	.	.	.
cord-308279-gsk4qel5	13	1	Severe	severe	JJ
cord-308279-gsk4qel5	13	2	acute	acute	JJ
cord-308279-gsk4qel5	13	3	respiratory	respiratory	JJ
cord-308279-gsk4qel5	13	4	syndrome	syndrome	NN
cord-308279-gsk4qel5	13	5	coronavirus	coronavirus	NN
cord-308279-gsk4qel5	13	6	2	2	CD
cord-308279-gsk4qel5	14	1	(	(	-LRB-
cord-308279-gsk4qel5	14	2	SARS	SARS	NNP
cord-308279-gsk4qel5	14	3	-	-	HYPH
cord-308279-gsk4qel5	14	4	CoV-2	CoV-2	NNP
cord-308279-gsk4qel5	14	5	)	)	-RRB-
cord-308279-gsk4qel5	14	6	is	be	VBZ
cord-308279-gsk4qel5	14	7	causing	cause	VBG
cord-308279-gsk4qel5	14	8	the	the	DT
cord-308279-gsk4qel5	14	9	current	current	JJ
cord-308279-gsk4qel5	14	10	pandemic	pandemic	NN
cord-308279-gsk4qel5	14	11	of	of	IN
cord-308279-gsk4qel5	14	12	coronavirus	coronavirus	NN
cord-308279-gsk4qel5	14	13	disease	disease	NN
cord-308279-gsk4qel5	14	14	2019	2019	CD
cord-308279-gsk4qel5	14	15	(	(	-LRB-
cord-308279-gsk4qel5	14	16	COVID-19	COVID-19	NNP
cord-308279-gsk4qel5	14	17	)	)	-RRB-
cord-308279-gsk4qel5	14	18	that	that	WDT
cord-308279-gsk4qel5	14	19	have	have	VBP
cord-308279-gsk4qel5	14	20	killed	kill	VBN
cord-308279-gsk4qel5	14	21	nearly	nearly	RB
cord-308279-gsk4qel5	14	22	one	one	CD
cord-308279-gsk4qel5	14	23	million	million	CD
cord-308279-gsk4qel5	14	24	people	people	NNS
cord-308279-gsk4qel5	14	25	so	so	RB
cord-308279-gsk4qel5	14	26	far	far	RB
cord-308279-gsk4qel5	14	27	.	.	.
cord-308279-gsk4qel5	15	1	While	while	IN
cord-308279-gsk4qel5	15	2	this	this	DT
cord-308279-gsk4qel5	15	3	appears	appear	VBZ
cord-308279-gsk4qel5	15	4	to	to	TO
cord-308279-gsk4qel5	15	5	be	be	VB
cord-308279-gsk4qel5	15	6	a	a	DT
cord-308279-gsk4qel5	15	7	respiratory	respiratory	JJ
cord-308279-gsk4qel5	15	8	virus	virus	NN
cord-308279-gsk4qel5	15	9	,	,	,
cord-308279-gsk4qel5	15	10	surprisingly	surprisingly	RB
cord-308279-gsk4qel5	15	11	,	,	,
cord-308279-gsk4qel5	15	12	it	-PRON-	PRP
cord-308279-gsk4qel5	15	13	has	have	VBZ
cord-308279-gsk4qel5	15	14	been	be	VBN
cord-308279-gsk4qel5	15	15	recognized	recognize	VBN
cord-308279-gsk4qel5	15	16	that	that	IN
cord-308279-gsk4qel5	15	17	patients	patient	NNS
cord-308279-gsk4qel5	15	18	with	with	IN
cord-308279-gsk4qel5	15	19	cardiovascular	cardiovascular	JJ
cord-308279-gsk4qel5	15	20	disease	disease	NN
cord-308279-gsk4qel5	15	21	are	be	VBP
cord-308279-gsk4qel5	15	22	likely	likely	JJ
cord-308279-gsk4qel5	15	23	to	to	TO
cord-308279-gsk4qel5	15	24	be	be	VB
cord-308279-gsk4qel5	15	25	affected	affect	VBN
cord-308279-gsk4qel5	15	26	severely	severely	RB
cord-308279-gsk4qel5	15	27	and	and	CC
cord-308279-gsk4qel5	15	28	die	die	VB
cord-308279-gsk4qel5	15	29	of	of	IN
cord-308279-gsk4qel5	15	30	COVID-19	COVID-19	NNP
cord-308279-gsk4qel5	15	31	.	.	.
cord-308279-gsk4qel5	16	1	This	this	DT
cord-308279-gsk4qel5	16	2	 	 	_SP
cord-308279-gsk4qel5	16	3	Viruses	virus	NNS
cord-308279-gsk4qel5	16	4	invade	invade	VBP
cord-308279-gsk4qel5	16	5	host	host	NN
cord-308279-gsk4qel5	16	6	cells	cell	NNS
cord-308279-gsk4qel5	16	7	,	,	,
cord-308279-gsk4qel5	16	8	resulting	result	VBG
cord-308279-gsk4qel5	16	9	in	in	IN
cord-308279-gsk4qel5	16	10	cell	cell	NN
cord-308279-gsk4qel5	16	11	death	death	NN
cord-308279-gsk4qel5	16	12	.	.	.
cord-308279-gsk4qel5	17	1	The	the	DT
cord-308279-gsk4qel5	17	2	major	major	JJ
cord-308279-gsk4qel5	17	3	target	target	NN
cord-308279-gsk4qel5	17	4	cells	cell	NNS
cord-308279-gsk4qel5	17	5	for	for	IN
cord-308279-gsk4qel5	17	6	SARS	SARS	NNP
cord-308279-gsk4qel5	17	7	-	-	HYPH
cord-308279-gsk4qel5	17	8	CoV-2	CoV-2	NNP
cord-308279-gsk4qel5	17	9	should	should	MD
cord-308279-gsk4qel5	17	10	be	be	VB
cord-308279-gsk4qel5	17	11	respiratory	respiratory	JJ
cord-308279-gsk4qel5	17	12	cells	cell	NNS
cord-308279-gsk4qel5	17	13	.	.	.
cord-308279-gsk4qel5	18	1	However	however	RB
cord-308279-gsk4qel5	18	2	,	,	,
cord-308279-gsk4qel5	18	3	surprisingly	surprisingly	RB
cord-308279-gsk4qel5	18	4	,	,	,
cord-308279-gsk4qel5	18	5	patients	patient	NNS
cord-308279-gsk4qel5	18	6	with	with	IN
cord-308279-gsk4qel5	18	7	cardiovascular	cardiovascular	JJ
cord-308279-gsk4qel5	18	8	disease	disease	NN
cord-308279-gsk4qel5	18	9	,	,	,
cord-308279-gsk4qel5	18	10	rather	rather	RB
cord-308279-gsk4qel5	18	11	than	than	IN
cord-308279-gsk4qel5	18	12	respiratory	respiratory	JJ
cord-308279-gsk4qel5	18	13	disease	disease	NN
cord-308279-gsk4qel5	18	14	,	,	,
cord-308279-gsk4qel5	18	15	are	be	VBP
cord-308279-gsk4qel5	18	16	predisposed	predisposed	JJ
cord-308279-gsk4qel5	18	17	to	to	TO
cord-308279-gsk4qel5	18	18	severe	severe	JJ
cord-308279-gsk4qel5	18	19	COVID-19	covid-19	JJ
cord-308279-gsk4qel5	18	20	symptoms	symptom	NNS
cord-308279-gsk4qel5	18	21	and	and	CC
cord-308279-gsk4qel5	18	22	death	death	NN
cord-308279-gsk4qel5	18	23	.	.	.
cord-308279-gsk4qel5	19	1	To	to	TO
cord-308279-gsk4qel5	19	2	explain	explain	VB
cord-308279-gsk4qel5	19	3	this	this	DT
cord-308279-gsk4qel5	19	4	phenomenon	phenomenon	NN
cord-308279-gsk4qel5	19	5	,	,	,
cord-308279-gsk4qel5	19	6	I	-PRON-	PRP
cord-308279-gsk4qel5	19	7	herein	herein	RB
cord-308279-gsk4qel5	19	8	propose	propose	VBP
cord-308279-gsk4qel5	19	9	the	the	DT
cord-308279-gsk4qel5	19	10	viral	viral	JJ
cord-308279-gsk4qel5	19	11	protein	protein	NN
cord-308279-gsk4qel5	19	12	fragment	fragment	NN
cord-308279-gsk4qel5	19	13	theory	theory	NN
cord-308279-gsk4qel5	19	14	of	of	IN
cord-308279-gsk4qel5	19	15	COVID-19	covid-19	JJ
cord-308279-gsk4qel5	19	16	pathogenesis	pathogenesis	NN
cord-308279-gsk4qel5	19	17	(	(	-LRB-
cord-308279-gsk4qel5	19	18	Fig	fig	NN
cord-308279-gsk4qel5	19	19	.	.	.
cord-308279-gsk4qel5	19	20	1	1	CD
cord-308279-gsk4qel5	19	21	)	)	-RRB-
cord-308279-gsk4qel5	19	22	.	.	.
cord-308279-gsk4qel5	20	1	This	this	DT
cord-308279-gsk4qel5	20	2	hypothesis	hypothesis	NN
cord-308279-gsk4qel5	20	3	is	be	VBZ
cord-308279-gsk4qel5	20	4	based	base	VBN
cord-308279-gsk4qel5	20	5	on	on	IN
cord-308279-gsk4qel5	20	6	my	-PRON-	PRP$
cord-308279-gsk4qel5	20	7	experimental	experimental	JJ
cord-308279-gsk4qel5	20	8	observations	observation	NNS
cord-308279-gsk4qel5	20	9	in	in	IN
cord-308279-gsk4qel5	20	10	cultured	cultured	JJ
cord-308279-gsk4qel5	20	11	human	human	JJ
cord-308279-gsk4qel5	20	12	vascular	vascular	JJ
cord-308279-gsk4qel5	20	13	cells	cell	NNS
cord-308279-gsk4qel5	20	14	that	that	IN
cord-308279-gsk4qel5	20	15	the	the	DT
cord-308279-gsk4qel5	20	16	recombinant	recombinant	JJ
cord-308279-gsk4qel5	20	17	full	full	JJ
cord-308279-gsk4qel5	20	18	length	length	NN
cord-308279-gsk4qel5	20	19	S1	s1	NN
cord-308279-gsk4qel5	20	20	subunit	subunit	NN
cord-308279-gsk4qel5	20	21	of	of	IN
cord-308279-gsk4qel5	20	22	SARS	SARS	NNP
cord-308279-gsk4qel5	20	23	-	-	HYPH
cord-308279-gsk4qel5	20	24	CoV-2	CoV-2	NNP
cord-308279-gsk4qel5	20	25	spike	spike	NN
cord-308279-gsk4qel5	20	26	protein	protein	NN
cord-308279-gsk4qel5	20	27	can	can	MD
cord-308279-gsk4qel5	20	28	activate	activate	VB
cord-308279-gsk4qel5	20	29	cell	cell	NN
cord-308279-gsk4qel5	20	30	signaling	signal	VBG
cord-308279-gsk4qel5	20	31	events	event	NNS
cord-308279-gsk4qel5	20	32	without	without	IN
cord-308279-gsk4qel5	20	33	the	the	DT
cord-308279-gsk4qel5	20	34	rest	rest	NN
cord-308279-gsk4qel5	20	35	of	of	IN
cord-308279-gsk4qel5	20	36	the	the	DT
cord-308279-gsk4qel5	20	37	viral	viral	JJ
cord-308279-gsk4qel5	20	38	components	component	NNS
cord-308279-gsk4qel5	20	39	.	.	.
cord-308279-gsk4qel5	21	1	11	11	CD
cord-308279-gsk4qel5	22	1	Thus	thus	RB
cord-308279-gsk4qel5	22	2	,	,	,
cord-308279-gsk4qel5	22	3	the	the	DT
cord-308279-gsk4qel5	22	4	pathology	pathology	NN
cord-308279-gsk4qel5	22	5	of	of	IN
cord-308279-gsk4qel5	22	6	COVID-19	COVID-19	NNP
cord-308279-gsk4qel5	22	7	may	may	MD
cord-308279-gsk4qel5	22	8	not	not	RB
cord-308279-gsk4qel5	22	9	merely	merely	RB
cord-308279-gsk4qel5	22	10	depend	depend	VB
cord-308279-gsk4qel5	22	11	on	on	IN
cord-308279-gsk4qel5	22	12	the	the	DT
cord-308279-gsk4qel5	22	13	spike	spike	NN
cord-308279-gsk4qel5	22	14	protein	protein	NN
cord-308279-gsk4qel5	22	15	serving	serve	VBG
cord-308279-gsk4qel5	22	16	as	as	IN
cord-308279-gsk4qel5	22	17	a	a	DT
cord-308279-gsk4qel5	22	18	fusion	fusion	NN
cord-308279-gsk4qel5	22	19	protein	protein	NN
cord-308279-gsk4qel5	22	20	to	to	TO
cord-308279-gsk4qel5	22	21	facilitate	facilitate	VB
cord-308279-gsk4qel5	22	22	the	the	DT
cord-308279-gsk4qel5	22	23	viral	viral	JJ
cord-308279-gsk4qel5	22	24	entry	entry	NN
cord-308279-gsk4qel5	22	25	and	and	CC
cord-308279-gsk4qel5	22	26	the	the	DT
cord-308279-gsk4qel5	22	27	infection	infection	NN
cord-308279-gsk4qel5	22	28	.	.	.
cord-308279-gsk4qel5	23	1	I	-PRON-	PRP
cord-308279-gsk4qel5	23	2	propose	propose	VBP
cord-308279-gsk4qel5	23	3	a	a	DT
cord-308279-gsk4qel5	23	4	scenario	scenario	NN
cord-308279-gsk4qel5	23	5	that	that	IN
cord-308279-gsk4qel5	23	6	,	,	,
cord-308279-gsk4qel5	23	7	as	as	IN
cord-308279-gsk4qel5	23	8	humans	human	NNS
cord-308279-gsk4qel5	23	9	are	be	VBP
cord-308279-gsk4qel5	23	10	infected	infect	VBN
cord-308279-gsk4qel5	23	11	with	with	IN
cord-308279-gsk4qel5	23	12	SARS	SARS	NNP
cord-308279-gsk4qel5	23	13	-	-	HYPH
cord-308279-gsk4qel5	23	14	CoV-2	CoV-2	NNP
cord-308279-gsk4qel5	23	15	,	,	,
cord-308279-gsk4qel5	23	16	the	the	DT
cord-308279-gsk4qel5	23	17	virus	virus	NN
cord-308279-gsk4qel5	23	18	releases	release	VBZ
cord-308279-gsk4qel5	23	19	a	a	DT
cord-308279-gsk4qel5	23	20	fragment	fragment	NN
cord-308279-gsk4qel5	23	21	of	of	IN
cord-308279-gsk4qel5	23	22	the	the	DT
cord-308279-gsk4qel5	23	23	spike	spike	NN
cord-308279-gsk4qel5	23	24	protein	protein	NN
cord-308279-gsk4qel5	23	25	that	that	WDT
cord-308279-gsk4qel5	23	26	can	can	MD
cord-308279-gsk4qel5	23	27	target	target	VB
cord-308279-gsk4qel5	23	28	host	host	NN
cord-308279-gsk4qel5	23	29	cells	cell	NNS
cord-308279-gsk4qel5	23	30	for	for	IN
cord-308279-gsk4qel5	23	31	eliciting	elicit	VBG
cord-308279-gsk4qel5	23	32	cell	cell	NN
cord-308279-gsk4qel5	23	33	signaling	signaling	NN
cord-308279-gsk4qel5	23	34	.	.	.
cord-308279-gsk4qel5	24	1	Thus	thus	RB
cord-308279-gsk4qel5	24	2	,	,	,
cord-308279-gsk4qel5	24	3	infected	infected	JJ
cord-308279-gsk4qel5	24	4	patients	patient	NNS
cord-308279-gsk4qel5	24	5	would	would	MD
cord-308279-gsk4qel5	24	6	have	have	VB
cord-308279-gsk4qel5	24	7	at	at	RB
cord-308279-gsk4qel5	24	8	least	least	RBS
cord-308279-gsk4qel5	24	9	two	two	CD
cord-308279-gsk4qel5	24	10	entities	entity	NNS
cord-308279-gsk4qel5	24	11	introduced	introduce	VBN
cord-308279-gsk4qel5	24	12	in	in	IN
cord-308279-gsk4qel5	24	13	response	response	NN
cord-308279-gsk4qel5	24	14	to	to	IN
cord-308279-gsk4qel5	24	15	the	the	DT
cord-308279-gsk4qel5	24	16	SARS	SARS	NNP
cord-308279-gsk4qel5	24	17	-	-	HYPH
cord-308279-gsk4qel5	24	18	CoV-2	CoV-2	NNP
cord-308279-gsk4qel5	24	19	infection	infection	NN
cord-308279-gsk4qel5	24	20	.	.	.
cord-308279-gsk4qel5	25	1	One	one	CD
cord-308279-gsk4qel5	25	2	is	be	VBZ
cord-308279-gsk4qel5	25	3	the	the	DT
cord-308279-gsk4qel5	25	4	intact	intact	JJ
cord-308279-gsk4qel5	25	5	virus	virus	NN
cord-308279-gsk4qel5	25	6	that	that	WDT
cord-308279-gsk4qel5	25	7	uses	use	VBZ
cord-308279-gsk4qel5	25	8	its	-PRON-	PRP$
cord-308279-gsk4qel5	25	9	spike	spike	NN
cord-308279-gsk4qel5	25	10	protein	protein	NN
cord-308279-gsk4qel5	25	11	to	to	TO
cord-308279-gsk4qel5	25	12	target	target	VB
cord-308279-gsk4qel5	25	13	ACE2	ACE2	NNP
cord-308279-gsk4qel5	25	14	,	,	,
cord-308279-gsk4qel5	25	15	resulting	result	VBG
cord-308279-gsk4qel5	25	16	in	in	IN
cord-308279-gsk4qel5	25	17	the	the	DT
cord-308279-gsk4qel5	25	18	entry	entry	NN
cord-308279-gsk4qel5	25	19	into	into	IN
cord-308279-gsk4qel5	25	20	the	the	DT
cord-308279-gsk4qel5	25	21	host	host	NN
cord-308279-gsk4qel5	25	22	cells	cell	NNS
cord-308279-gsk4qel5	25	23	for	for	IN
cord-308279-gsk4qel5	25	24	the	the	DT
cord-308279-gsk4qel5	25	25	viral	viral	JJ
cord-308279-gsk4qel5	25	26	replication	replication	NN
cord-308279-gsk4qel5	25	27	and	and	CC
cord-308279-gsk4qel5	25	28	amplification	amplification	NN
cord-308279-gsk4qel5	25	29	.	.	.
cord-308279-gsk4qel5	26	1	The	the	DT
cord-308279-gsk4qel5	26	2	other	other	JJ
cord-308279-gsk4qel5	26	3	is	be	VBZ
cord-308279-gsk4qel5	26	4	the	the	DT
cord-308279-gsk4qel5	26	5	circulating	circulate	VBG
cord-308279-gsk4qel5	26	6	fragment	fragment	NN
cord-308279-gsk4qel5	26	7	of	of	IN
cord-308279-gsk4qel5	26	8	the	the	DT
cord-308279-gsk4qel5	26	9	spike	spike	NN
cord-308279-gsk4qel5	26	10	protein	protein	NN
cord-308279-gsk4qel5	26	11	that	that	WDT
cord-308279-gsk4qel5	26	12	independently	independently	RB
cord-308279-gsk4qel5	26	13	elicits	elicit	VBZ
cord-308279-gsk4qel5	26	14	actions	action	NNS
cord-308279-gsk4qel5	26	15	that	that	WDT
cord-308279-gsk4qel5	26	16	ultimately	ultimately	RB
cord-308279-gsk4qel5	26	17	results	result	VBZ
cord-308279-gsk4qel5	26	18	in	in	IN
cord-308279-gsk4qel5	26	19	severe	severe	JJ
cord-308279-gsk4qel5	26	20	pathological	pathological	JJ
cord-308279-gsk4qel5	26	21	conditions	condition	NNS
cord-308279-gsk4qel5	26	22	.	.	.
cord-308279-gsk4qel5	27	1	My	-PRON-	PRP$
cord-308279-gsk4qel5	27	2	experiments	experiment	NNS
cord-308279-gsk4qel5	27	3	using	use	VBG
cord-308279-gsk4qel5	27	4	cultured	cultured	JJ
cord-308279-gsk4qel5	27	5	vascular	vascular	JJ
cord-308279-gsk4qel5	27	6	cells	cell	NNS
cord-308279-gsk4qel5	27	7	also	also	RB
cord-308279-gsk4qel5	27	8	showed	show	VBD
cord-308279-gsk4qel5	27	9	that	that	IN
cord-308279-gsk4qel5	27	10	,	,	,
cord-308279-gsk4qel5	27	11	while	while	IN
cord-308279-gsk4qel5	27	12	the	the	DT
cord-308279-gsk4qel5	27	13	full	full	JJ
cord-308279-gsk4qel5	27	14	length	length	NN
cord-308279-gsk4qel5	27	15	S1	S1	NNP
cord-308279-gsk4qel5	27	16	subunit	subunit	NN
cord-308279-gsk4qel5	27	17	of	of	IN
cord-308279-gsk4qel5	27	18	SARS	SARS	NNP
cord-308279-gsk4qel5	27	19	-	-	HYPH
cord-308279-gsk4qel5	27	20	CoV-2	CoV-2	NNP
cord-308279-gsk4qel5	27	21	spike	spike	NN
cord-308279-gsk4qel5	27	22	protein	protein	NN
cord-308279-gsk4qel5	27	23	elicits	elicit	VBZ
cord-308279-gsk4qel5	27	24	cell	cell	NN
cord-308279-gsk4qel5	27	25	signaling	signal	VBG
cord-308279-gsk4qel5	27	26	,	,	,
cord-308279-gsk4qel5	27	27	the	the	DT
cord-308279-gsk4qel5	27	28	shorter	short	JJR
cord-308279-gsk4qel5	27	29	protein	protein	NN
cord-308279-gsk4qel5	27	30	that	that	IN
cord-308279-gsk4qel5	27	31	only	only	RB
cord-308279-gsk4qel5	27	32	contains	contain	VBZ
cord-308279-gsk4qel5	27	33	the	the	DT
cord-308279-gsk4qel5	27	34	receptor	receptor	NN
cord-308279-gsk4qel5	27	35	binding	bind	VBG
cord-308279-gsk4qel5	27	36	domain	domain	NN
cord-308279-gsk4qel5	27	37	(	(	-LRB-
cord-308279-gsk4qel5	27	38	RBD	RBD	NNP
cord-308279-gsk4qel5	27	39	)	)	-RRB-
cord-308279-gsk4qel5	27	40	does	do	VBZ
cord-308279-gsk4qel5	27	41	not	not	RB
cord-308279-gsk4qel5	27	42	.	.	.
cord-308279-gsk4qel5	28	1	11	11	CD
cord-308279-gsk4qel5	29	1	These	these	DT
cord-308279-gsk4qel5	29	2	results	result	NNS
cord-308279-gsk4qel5	29	3	suggest	suggest	VBP
cord-308279-gsk4qel5	29	4	that	that	IN
cord-308279-gsk4qel5	29	5	other	other	JJ
cord-308279-gsk4qel5	29	6	regions	region	NNS
cord-308279-gsk4qel5	29	7	of	of	IN
cord-308279-gsk4qel5	29	8	the	the	DT
cord-308279-gsk4qel5	29	9	S1	S1	NNP
cord-308279-gsk4qel5	29	10	subunit	subunit	NN
cord-308279-gsk4qel5	29	11	are	be	VBP
cord-308279-gsk4qel5	29	12	responsible	responsible	JJ
cord-308279-gsk4qel5	29	13	for	for	IN
cord-308279-gsk4qel5	29	14	eliciting	elicit	VBG
cord-308279-gsk4qel5	29	15	cell	cell	NN
cord-308279-gsk4qel5	29	16	signaling	signal	VBG
cord-308279-gsk4qel5	29	17	in	in	IN
cord-308279-gsk4qel5	29	18	host	host	NN
cord-308279-gsk4qel5	29	19	cells	cell	NNS
cord-308279-gsk4qel5	29	20	.	.	.
cord-308279-gsk4qel5	30	1	Thus	thus	RB
cord-308279-gsk4qel5	30	2	,	,	,
cord-308279-gsk4qel5	30	3	if	if	IN
cord-308279-gsk4qel5	30	4	the	the	DT
cord-308279-gsk4qel5	30	5	SARS	SARS	NNP
cord-308279-gsk4qel5	30	6	-	-	HYPH
cord-308279-gsk4qel5	30	7	CoV-2	CoV-2	NNP
cord-308279-gsk4qel5	30	8	spike	spike	NN
cord-308279-gsk4qel5	30	9	protein	protein	NN
cord-308279-gsk4qel5	30	10	fragment	fragment	NN
cord-308279-gsk4qel5	30	11	that	that	WDT
cord-308279-gsk4qel5	30	12	has	have	VBZ
cord-308279-gsk4qel5	30	13	been	be	VBN
cord-308279-gsk4qel5	30	14	released	release	VBN
cord-308279-gsk4qel5	30	15	into	into	IN
cord-308279-gsk4qel5	30	16	our	-PRON-	PRP$
cord-308279-gsk4qel5	30	17	blood	blood	NN
cord-308279-gsk4qel5	30	18	is	be	VBZ
cord-308279-gsk4qel5	30	19	responsible	responsible	JJ
cord-308279-gsk4qel5	30	20	for	for	IN
cord-308279-gsk4qel5	30	21	the	the	DT
cord-308279-gsk4qel5	30	22	pathogenesis	pathogenesis	NN
cord-308279-gsk4qel5	30	23	of	of	IN
cord-308279-gsk4qel5	30	24	severe	severe	JJ
cord-308279-gsk4qel5	30	25	COVID-19	covid-19	NN
cord-308279-gsk4qel5	30	26	,	,	,
cord-308279-gsk4qel5	30	27	therapies	therapy	NNS
cord-308279-gsk4qel5	30	28	that	that	WDT
cord-308279-gsk4qel5	30	29	target	target	VBP
cord-308279-gsk4qel5	30	30	the	the	DT
cord-308279-gsk4qel5	30	31	viral	viral	JJ
cord-308279-gsk4qel5	30	32	replication	replication	NN
cord-308279-gsk4qel5	30	33	such	such	JJ
cord-308279-gsk4qel5	30	34	as	as	IN
cord-308279-gsk4qel5	30	35	inhibitors	inhibitor	NNS
cord-308279-gsk4qel5	30	36	of	of	IN
cord-308279-gsk4qel5	30	37	RNA	RNA	NNP
cord-308279-gsk4qel5	30	38	-	-	HYPH
cord-308279-gsk4qel5	30	39	dependent	dependent	JJ
cord-308279-gsk4qel5	30	40	RNA	RNA	NNP
cord-308279-gsk4qel5	30	41	polymerase	polymerase	NN
cord-308279-gsk4qel5	30	42	alone	alone	RB
cord-308279-gsk4qel5	30	43	would	would	MD
cord-308279-gsk4qel5	30	44	not	not	RB
cord-308279-gsk4qel5	30	45	work	work	VB
cord-308279-gsk4qel5	30	46	.	.	.
cord-308279-gsk4qel5	31	1	Also	also	RB
cord-308279-gsk4qel5	31	2	,	,	,
cord-308279-gsk4qel5	31	3	if	if	IN
cord-308279-gsk4qel5	31	4	the	the	DT
cord-308279-gsk4qel5	31	5	regions	region	NNS
cord-308279-gsk4qel5	31	6	of	of	IN
cord-308279-gsk4qel5	31	7	spike	spike	NN
cord-308279-gsk4qel5	31	8	protein	protein	NN
cord-308279-gsk4qel5	31	9	other	other	JJ
cord-308279-gsk4qel5	31	10	than	than	IN
cord-308279-gsk4qel5	31	11	the	the	DT
cord-308279-gsk4qel5	31	12	RBD	RBD	NNP
cord-308279-gsk4qel5	31	13	are	be	VBP
cord-308279-gsk4qel5	31	14	responsible	responsible	JJ
cord-308279-gsk4qel5	31	15	for	for	IN
cord-308279-gsk4qel5	31	16	eliciting	elicit	VBG
cord-308279-gsk4qel5	31	17	pathological	pathological	JJ
cord-308279-gsk4qel5	31	18	cell	cell	NN
cord-308279-gsk4qel5	31	19	signaling	signaling	NN
cord-308279-gsk4qel5	31	20	and	and	CC
cord-308279-gsk4qel5	31	21	if	if	IN
cord-308279-gsk4qel5	31	22	the	the	DT
cord-308279-gsk4qel5	31	23	fragment	fragment	NN
cord-308279-gsk4qel5	31	24	is	be	VBZ
cord-308279-gsk4qel5	31	25	released	release	VBN
cord-308279-gsk4qel5	31	26	quickly	quickly	RB
cord-308279-gsk4qel5	31	27	after	after	IN
cord-308279-gsk4qel5	31	28	the	the	DT
cord-308279-gsk4qel5	31	29	host	host	NN
cord-308279-gsk4qel5	31	30	is	be	VBZ
cord-308279-gsk4qel5	31	31	exposed	expose	VBN
cord-308279-gsk4qel5	31	32	to	to	IN
cord-308279-gsk4qel5	31	33	SARS	SARS	NNP
cord-308279-gsk4qel5	31	34	-	-	HYPH
cord-308279-gsk4qel5	31	35	CoV-2	CoV-2	NNP
cord-308279-gsk4qel5	31	36	,	,	,
cord-308279-gsk4qel5	31	37	then	then	RB
cord-308279-gsk4qel5	31	38	vaccines	vaccine	NNS
cord-308279-gsk4qel5	31	39	that	that	WDT
cord-308279-gsk4qel5	31	40	target	target	VBP
cord-308279-gsk4qel5	31	41	RBD	RBD	NNP
cord-308279-gsk4qel5	31	42	would	would	MD
cord-308279-gsk4qel5	31	43	not	not	RB
cord-308279-gsk4qel5	31	44	affect	affect	VB
cord-308279-gsk4qel5	31	45	the	the	DT
cord-308279-gsk4qel5	31	46	viral	viral	JJ
cord-308279-gsk4qel5	31	47	fragment	fragment	NN
cord-308279-gsk4qel5	31	48	-	-	HYPH
cord-308279-gsk4qel5	31	49	mediated	mediate	VBN
cord-308279-gsk4qel5	31	50	cell	cell	NN
cord-308279-gsk4qel5	31	51	signaling	signaling	NN
cord-308279-gsk4qel5	31	52	.	.	.
cord-308279-gsk4qel5	32	1	Thus	thus	RB
cord-308279-gsk4qel5	32	2	,	,	,
cord-308279-gsk4qel5	32	3	therapeutic	therapeutic	JJ
cord-308279-gsk4qel5	32	4	strategies	strategy	NNS
cord-308279-gsk4qel5	32	5	to	to	TO
cord-308279-gsk4qel5	32	6	inhibit	inhibit	VB
cord-308279-gsk4qel5	32	7	viral	viral	JJ
cord-308279-gsk4qel5	32	8	fragment	fragment	NN
cord-308279-gsk4qel5	32	9	-	-	HYPH
cord-308279-gsk4qel5	32	10	mediated	mediate	VBN
cord-308279-gsk4qel5	32	11	cell	cell	NN
cord-308279-gsk4qel5	32	12	signaling	signal	VBG
cord-308279-gsk4qel5	32	13	in	in	IN
cord-308279-gsk4qel5	32	14	cardiovascular	cardiovascular	JJ
cord-308279-gsk4qel5	32	15	cells	cell	NNS
cord-308279-gsk4qel5	32	16	,	,	,
cord-308279-gsk4qel5	32	17	in	in	IN
cord-308279-gsk4qel5	32	18	addition	addition	NN
cord-308279-gsk4qel5	32	19	to	to	IN
cord-308279-gsk4qel5	32	20	drugs	drug	NNS
cord-308279-gsk4qel5	32	21	that	that	WDT
cord-308279-gsk4qel5	32	22	inhibits	inhibit	VBZ
cord-308279-gsk4qel5	32	23	the	the	DT
cord-308279-gsk4qel5	32	24	viral	viral	JJ
cord-308279-gsk4qel5	32	25	replication	replication	NN
cord-308279-gsk4qel5	32	26	,	,	,
cord-308279-gsk4qel5	32	27	are	be	VBP
cord-308279-gsk4qel5	32	28	necessary	necessary	JJ
cord-308279-gsk4qel5	32	29	to	to	TO
cord-308279-gsk4qel5	32	30	reduce	reduce	VB
cord-308279-gsk4qel5	32	31	the	the	DT
cord-308279-gsk4qel5	32	32	COVID-19-associated	covid-19-associated	JJ
cord-308279-gsk4qel5	32	33	death	death	NN
cord-308279-gsk4qel5	32	34	.	.	.
cord-308279-gsk4qel5	33	1	My	-PRON-	PRP$
cord-308279-gsk4qel5	33	2	specific	specific	JJ
cord-308279-gsk4qel5	33	3	hypothesis	hypothesis	NN
cord-308279-gsk4qel5	33	4	is	be	VBZ
cord-308279-gsk4qel5	33	5	that	that	IN
cord-308279-gsk4qel5	33	6	certain	certain	JJ
cord-308279-gsk4qel5	33	7	viruses	virus	NNS
cord-308279-gsk4qel5	33	8	shed	shed	VBP
cord-308279-gsk4qel5	33	9	fusion	fusion	NN
cord-308279-gsk4qel5	33	10	protein	protein	NN
cord-308279-gsk4qel5	33	11	fragments	fragment	NNS
cord-308279-gsk4qel5	33	12	that	that	WDT
cord-308279-gsk4qel5	33	13	circulate	circulate	VBP
cord-308279-gsk4qel5	33	14	in	in	IN
cord-308279-gsk4qel5	33	15	the	the	DT
cord-308279-gsk4qel5	33	16	blood	blood	NN
cord-308279-gsk4qel5	33	17	that	that	WDT
cord-308279-gsk4qel5	33	18	,	,	,
cord-308279-gsk4qel5	33	19	in	in	IN
cord-308279-gsk4qel5	33	20	turn	turn	NN
cord-308279-gsk4qel5	33	21	,	,	,
cord-308279-gsk4qel5	33	22	elicit	elicit	VB
cord-308279-gsk4qel5	33	23	cell	cell	NN
cord-308279-gsk4qel5	33	24	signal	signal	NN
cord-308279-gsk4qel5	33	25	transduction	transduction	NN
cord-308279-gsk4qel5	33	26	that	that	WDT
cord-308279-gsk4qel5	33	27	makes	make	VBZ
cord-308279-gsk4qel5	33	28	the	the	DT
cord-308279-gsk4qel5	33	29	infected	infected	JJ
cord-308279-gsk4qel5	33	30	individuals	individual	NNS
cord-308279-gsk4qel5	33	31	with	with	IN
cord-308279-gsk4qel5	33	32	cardiovascular	cardiovascular	JJ
cord-308279-gsk4qel5	33	33	diseases	disease	NNS
cord-308279-gsk4qel5	33	34	predisposed	predisposed	JJ
cord-308279-gsk4qel5	33	35	to	to	TO
cord-308279-gsk4qel5	33	36	severe	severe	JJ
cord-308279-gsk4qel5	33	37	COVID-19	covid-19	JJ
cord-308279-gsk4qel5	33	38	conditions	condition	NNS
cord-308279-gsk4qel5	33	39	and	and	CC
cord-308279-gsk4qel5	33	40	death	death	NN
cord-308279-gsk4qel5	33	41	.	.	.
cord-308279-gsk4qel5	34	1	Thus	thus	RB
cord-308279-gsk4qel5	34	2	,	,	,
cord-308279-gsk4qel5	34	3	infected	infected	JJ
cord-308279-gsk4qel5	34	4	patients	patient	NNS
cord-308279-gsk4qel5	34	5	would	would	MD
cord-308279-gsk4qel5	34	6	have	have	VB
cord-308279-gsk4qel5	34	7	at	at	RB
cord-308279-gsk4qel5	34	8	least	least	RBS
cord-308279-gsk4qel5	34	9	two	two	CD
cord-308279-gsk4qel5	34	10	entities	entity	NNS
cord-308279-gsk4qel5	34	11	that	that	WDT
cord-308279-gsk4qel5	34	12	may	may	MD
cord-308279-gsk4qel5	34	13	cause	cause	VB
cord-308279-gsk4qel5	34	14	complications	complication	NNS
cord-308279-gsk4qel5	34	15	when	when	WRB
cord-308279-gsk4qel5	34	16	they	-PRON-	PRP
cord-308279-gsk4qel5	34	17	are	be	VBP
cord-308279-gsk4qel5	34	18	infected	infect	VBN
cord-308279-gsk4qel5	34	19	with	with	IN
cord-308279-gsk4qel5	34	20	SARS	SARS	NNP
cord-308279-gsk4qel5	34	21	-	-	HYPH
cord-308279-gsk4qel5	34	22	CoV-2	CoV-2	NNP
cord-308279-gsk4qel5	34	23	:	:	:
cord-308279-gsk4qel5	34	24	(	(	-LRB-
cord-308279-gsk4qel5	34	25	i	i	NN
cord-308279-gsk4qel5	34	26	)	)	-RRB-
cord-308279-gsk4qel5	34	27	virus	virus	NN
cord-308279-gsk4qel5	34	28	itself	-PRON-	PRP
cord-308279-gsk4qel5	34	29	that	that	WDT
cord-308279-gsk4qel5	34	30	gets	get	VBZ
cord-308279-gsk4qel5	34	31	incorporated	incorporate	VBN
cord-308279-gsk4qel5	34	32	into	into	IN
cord-308279-gsk4qel5	34	33	the	the	DT
cord-308279-gsk4qel5	34	34	host	host	NN
cord-308279-gsk4qel5	34	35	cells	cell	NNS
cord-308279-gsk4qel5	34	36	where	where	WRB
cord-308279-gsk4qel5	34	37	the	the	DT
cord-308279-gsk4qel5	34	38	viral	viral	JJ
cord-308279-gsk4qel5	34	39	replication	replication	NN
cord-308279-gsk4qel5	34	40	and	and	CC
cord-308279-gsk4qel5	34	41	amplification	amplification	NN
cord-308279-gsk4qel5	34	42	occur	occur	VBP
cord-308279-gsk4qel5	34	43	;	;	:
cord-308279-gsk4qel5	34	44	and	and	CC
cord-308279-gsk4qel5	34	45	(	(	-LRB-
cord-308279-gsk4qel5	34	46	ii	ii	NN
cord-308279-gsk4qel5	34	47	)	)	-RRB-
cord-308279-gsk4qel5	34	48	components	component	NNS
cord-308279-gsk4qel5	34	49	of	of	IN
cord-308279-gsk4qel5	34	50	viral	viral	JJ
cord-308279-gsk4qel5	34	51	fusion	fusion	NN
cord-308279-gsk4qel5	34	52	proteins	protein	NNS
cord-308279-gsk4qel5	34	53	(	(	-LRB-
cord-308279-gsk4qel5	34	54	i.e.	i.e.	FW
cord-308279-gsk4qel5	34	55	spike	spike	NN
cord-308279-gsk4qel5	34	56	protein	protein	NN
cord-308279-gsk4qel5	34	57	for	for	IN
cord-308279-gsk4qel5	34	58	SARS	SARS	NNP
cord-308279-gsk4qel5	34	59	-	-	HYPH
cord-308279-gsk4qel5	34	60	CoV-2	CoV-2	NNP
cord-308279-gsk4qel5	34	61	)	)	-RRB-
cord-308279-gsk4qel5	34	62	that	that	WDT
cord-308279-gsk4qel5	34	63	are	be	VBP
cord-308279-gsk4qel5	34	64	circulated	circulate	VBN
cord-308279-gsk4qel5	34	65	to	to	TO
cord-308279-gsk4qel5	34	66	elicit	elicit	VB
cord-308279-gsk4qel5	34	67	distinct	distinct	JJ
cord-308279-gsk4qel5	34	68	processes	process	NNS
cord-308279-gsk4qel5	34	69	that	that	WDT
cord-308279-gsk4qel5	34	70	promote	promote	VBP
cord-308279-gsk4qel5	34	71	pathologic	pathologic	JJ
cord-308279-gsk4qel5	34	72	conditions	condition	NNS
cord-308279-gsk4qel5	34	73	.	.	.
cord-308279-gsk4qel5	35	1	This	this	DT
cord-308279-gsk4qel5	35	2	is	be	VBZ
cord-308279-gsk4qel5	35	3	based	base	VBN
cord-308279-gsk4qel5	35	4	on	on	IN
cord-308279-gsk4qel5	35	5	my	-PRON-	PRP$
cord-308279-gsk4qel5	35	6	observations	observation	NNS
cord-308279-gsk4qel5	35	7	that	that	IN
cord-308279-gsk4qel5	35	8	recombinant	recombinant	JJ
cord-308279-gsk4qel5	35	9	SARS	SARS	NNP
cord-308279-gsk4qel5	35	10	-	-	HYPH
cord-308279-gsk4qel5	35	11	CoV-2	CoV-2	NNP
cord-308279-gsk4qel5	35	12	spike	spike	NN
cord-308279-gsk4qel5	35	13	protein	protein	NN
cord-308279-gsk4qel5	35	14	(	(	-LRB-
cord-308279-gsk4qel5	35	15	without	without	IN
cord-308279-gsk4qel5	35	16	the	the	DT
cord-308279-gsk4qel5	35	17	rest	rest	NN
cord-308279-gsk4qel5	35	18	of	of	IN
cord-308279-gsk4qel5	35	19	the	the	DT
cord-308279-gsk4qel5	35	20	viruses	virus	NNS
cord-308279-gsk4qel5	35	21	)	)	-RRB-
cord-308279-gsk4qel5	35	22	is	be	VBZ
cord-308279-gsk4qel5	35	23	capable	capable	JJ
cord-308279-gsk4qel5	35	24	of	of	IN
cord-308279-gsk4qel5	35	25	eliciting	elicit	VBG
cord-308279-gsk4qel5	35	26	cell	cell	NN
cord-308279-gsk4qel5	35	27	signaling	signal	VBG
cord-308279-gsk4qel5	35	28	in	in	IN
cord-308279-gsk4qel5	35	29	cultured	cultured	JJ
cord-308279-gsk4qel5	35	30	human	human	JJ
cord-308279-gsk4qel5	35	31	vascular	vascular	JJ
cord-308279-gsk4qel5	35	32	cells	cell	NNS
cord-308279-gsk4qel5	35	33	.	.	.
cord-308279-gsk4qel5	36	1	11	11	CD
cord-308279-gsk4qel5	37	1	Interestingly	interestingly	RB
cord-308279-gsk4qel5	37	2	,	,	,
cord-308279-gsk4qel5	37	3	my	-PRON-	PRP$
cord-308279-gsk4qel5	37	4	experiments	experiment	NNS
cord-308279-gsk4qel5	37	5	also	also	RB
cord-308279-gsk4qel5	37	6	showed	show	VBD
cord-308279-gsk4qel5	37	7	that	that	IN
cord-308279-gsk4qel5	37	8	RBD	RBD	NNP
cord-308279-gsk4qel5	37	9	domain	domain	NN
cord-308279-gsk4qel5	37	10	-	-	HYPH
cord-308279-gsk4qel5	37	11	only	only	RB
cord-308279-gsk4qel5	37	12	containing	contain	VBG
cord-308279-gsk4qel5	37	13	protein	protein	NN
cord-308279-gsk4qel5	37	14	region	region	NN
cord-308279-gsk4qel5	37	15	of	of	IN
cord-308279-gsk4qel5	37	16	SARS	SARS	NNP
cord-308279-gsk4qel5	37	17	-	-	HYPH
cord-308279-gsk4qel5	37	18	CoV-2	CoV-2	NNP
cord-308279-gsk4qel5	37	19	spike	spike	NN
cord-308279-gsk4qel5	37	20	protein	protein	NN
cord-308279-gsk4qel5	37	21	does	do	VBZ
cord-308279-gsk4qel5	37	22	not	not	RB
cord-308279-gsk4qel5	37	23	activate	activate	VB
cord-308279-gsk4qel5	37	24	cell	cell	NN
cord-308279-gsk4qel5	37	25	signaling	signaling	NN
cord-308279-gsk4qel5	37	26	,	,	,
cord-308279-gsk4qel5	37	27	suggesting	suggest	VBG
cord-308279-gsk4qel5	37	28	the	the	DT
cord-308279-gsk4qel5	37	29	role	role	NN
cord-308279-gsk4qel5	37	30	of	of	IN
cord-308279-gsk4qel5	37	31	other	other	JJ
cord-308279-gsk4qel5	37	32	regions	region	NNS
cord-308279-gsk4qel5	37	33	with	with	IN
cord-308279-gsk4qel5	37	34	in	in	IN
cord-308279-gsk4qel5	37	35	the	the	DT
cord-308279-gsk4qel5	37	36	S1	S1	NNP
cord-308279-gsk4qel5	37	37	subunit	subunit	NN
cord-308279-gsk4qel5	37	38	of	of	IN
cord-308279-gsk4qel5	37	39	the	the	DT
cord-308279-gsk4qel5	37	40	SARS	SARS	NNP
cord-308279-gsk4qel5	37	41	-	-	HYPH
cord-308279-gsk4qel5	37	42	CoV-2	CoV-2	NNP
cord-308279-gsk4qel5	37	43	spike	spike	NN
cord-308279-gsk4qel5	37	44	protein	protein	NN
cord-308279-gsk4qel5	37	45	to	to	TO
cord-308279-gsk4qel5	37	46	activate	activate	VB
cord-308279-gsk4qel5	37	47	this	this	DT
cord-308279-gsk4qel5	37	48	cell	cell	NN
cord-308279-gsk4qel5	37	49	signaling	signal	VBG
cord-308279-gsk4qel5	37	50	event	event	NN
cord-308279-gsk4qel5	37	51	.	.	.
cord-308279-gsk4qel5	38	1	Thus	thus	RB
cord-308279-gsk4qel5	38	2	,	,	,
cord-308279-gsk4qel5	38	3	the	the	DT
cord-308279-gsk4qel5	38	4	first	first	JJ
cord-308279-gsk4qel5	38	5	experiments	experiment	NNS
cord-308279-gsk4qel5	38	6	that	that	WDT
cord-308279-gsk4qel5	38	7	are	be	VBP
cord-308279-gsk4qel5	38	8	needed	need	VBN
cord-308279-gsk4qel5	38	9	to	to	TO
cord-308279-gsk4qel5	38	10	test	test	VB
cord-308279-gsk4qel5	38	11	this	this	DT
cord-308279-gsk4qel5	38	12	hypothesis	hypothesis	NN
cord-308279-gsk4qel5	38	13	is	be	VBZ
cord-308279-gsk4qel5	38	14	to	to	TO
cord-308279-gsk4qel5	38	15	identify	identify	VB
cord-308279-gsk4qel5	38	16	the	the	DT
cord-308279-gsk4qel5	38	17	regions	region	NNS
cord-308279-gsk4qel5	38	18	of	of	IN
cord-308279-gsk4qel5	38	19	SARS	SARS	NNP
cord-308279-gsk4qel5	38	20	CoV-2	CoV-2	NNP
cord-308279-gsk4qel5	38	21	spike	spike	NN
cord-308279-gsk4qel5	38	22	protein	protein	NN
cord-308279-gsk4qel5	38	23	that	that	WDT
cord-308279-gsk4qel5	38	24	are	be	VBP
cord-308279-gsk4qel5	38	25	responsible	responsible	JJ
cord-308279-gsk4qel5	38	26	for	for	IN
cord-308279-gsk4qel5	38	27	activating	activate	VBG
cord-308279-gsk4qel5	38	28	cell	cell	NN
cord-308279-gsk4qel5	38	29	signaling	signaling	NN
cord-308279-gsk4qel5	38	30	,	,	,
cord-308279-gsk4qel5	38	31	perhaps	perhaps	RB
cord-308279-gsk4qel5	38	32	by	by	IN
cord-308279-gsk4qel5	38	33	using	use	VBG
cord-308279-gsk4qel5	38	34	cultured	cultured	JJ
cord-308279-gsk4qel5	38	35	human	human	JJ
cord-308279-gsk4qel5	38	36	cells	cell	NNS
cord-308279-gsk4qel5	38	37	.	.	.
cord-308279-gsk4qel5	39	1	After	after	IN
cord-308279-gsk4qel5	39	2	identifying	identify	VBG
cord-308279-gsk4qel5	39	3	active	active	JJ
cord-308279-gsk4qel5	39	4	protein	protein	NN
cord-308279-gsk4qel5	39	5	regions	region	NNS
cord-308279-gsk4qel5	39	6	of	of	IN
cord-308279-gsk4qel5	39	7	the	the	DT
cord-308279-gsk4qel5	39	8	S1	S1	NNP
cord-308279-gsk4qel5	39	9	subunit	subunit	NN
cord-308279-gsk4qel5	39	10	of	of	IN
cord-308279-gsk4qel5	39	11	SARS	SARS	NNP
cord-308279-gsk4qel5	39	12	-	-	HYPH
cord-308279-gsk4qel5	39	13	CoV-2	CoV-2	NNP
cord-308279-gsk4qel5	39	14	spike	spike	NN
cord-308279-gsk4qel5	39	15	protein	protein	NN
cord-308279-gsk4qel5	39	16	,	,	,
cord-308279-gsk4qel5	39	17	the	the	DT
cord-308279-gsk4qel5	39	18	occurrence	occurrence	NN
cord-308279-gsk4qel5	39	19	of	of	IN
cord-308279-gsk4qel5	39	20	protein	protein	NN
cord-308279-gsk4qel5	39	21	fragments	fragment	NNS
cord-308279-gsk4qel5	39	22	that	that	WDT
cord-308279-gsk4qel5	39	23	possess	possess	VBP
cord-308279-gsk4qel5	39	24	such	such	JJ
cord-308279-gsk4qel5	39	25	protein	protein	NN
cord-308279-gsk4qel5	39	26	sequences	sequence	NNS
cord-308279-gsk4qel5	39	27	should	should	MD
cord-308279-gsk4qel5	39	28	be	be	VB
cord-308279-gsk4qel5	39	29	detected	detect	VBN
cord-308279-gsk4qel5	39	30	in	in	IN
cord-308279-gsk4qel5	39	31	patients	patient	NNS
cord-308279-gsk4qel5	39	32	infected	infect	VBN
cord-308279-gsk4qel5	39	33	with	with	IN
cord-308279-gsk4qel5	39	34	SARS	SARS	NNP
cord-308279-gsk4qel5	39	35	-	-	HYPH
cord-308279-gsk4qel5	39	36	CoV-2	CoV-2	NNP
cord-308279-gsk4qel5	39	37	.	.	.
cord-308279-gsk4qel5	40	1	Experimental	experimental	JJ
cord-308279-gsk4qel5	40	2	animals	animal	NNS
cord-308279-gsk4qel5	40	3	should	should	MD
cord-308279-gsk4qel5	40	4	also	also	RB
cord-308279-gsk4qel5	40	5	be	be	VB
cord-308279-gsk4qel5	40	6	employed	employ	VBN
cord-308279-gsk4qel5	40	7	to	to	TO
cord-308279-gsk4qel5	40	8	determine	determine	VB
cord-308279-gsk4qel5	40	9	whether	whether	IN
cord-308279-gsk4qel5	40	10	the	the	DT
cord-308279-gsk4qel5	40	11	administrations	administration	NNS
cord-308279-gsk4qel5	40	12	of	of	IN
cord-308279-gsk4qel5	40	13	such	such	JJ
cord-308279-gsk4qel5	40	14	fragments	fragment	NNS
cord-308279-gsk4qel5	40	15	promotes	promote	VBZ
cord-308279-gsk4qel5	40	16	cardiovascular	cardiovascular	JJ
cord-308279-gsk4qel5	40	17	disease	disease	NN
cord-308279-gsk4qel5	40	18	conditions	condition	NNS
cord-308279-gsk4qel5	40	19	or	or	CC
cord-308279-gsk4qel5	40	20	worsens	worsen	VBZ
cord-308279-gsk4qel5	40	21	the	the	DT
cord-308279-gsk4qel5	40	22	existing	exist	VBG
cord-308279-gsk4qel5	40	23	cardiovascular	cardiovascular	JJ
cord-308279-gsk4qel5	40	24	pathology	pathology	NN
cord-308279-gsk4qel5	40	25	.	.	.
cord-308279-gsk4qel5	41	1	I	-PRON-	PRP
cord-308279-gsk4qel5	41	2	herein	herein	RB
cord-308279-gsk4qel5	41	3	propose	propose	VBP
cord-308279-gsk4qel5	41	4	the	the	DT
cord-308279-gsk4qel5	41	5	viral	viral	JJ
cord-308279-gsk4qel5	41	6	protein	protein	NN
cord-308279-gsk4qel5	41	7	fragment	fragment	NN
cord-308279-gsk4qel5	41	8	theory	theory	NN
cord-308279-gsk4qel5	41	9	of	of	IN
cord-308279-gsk4qel5	41	10	COVID-19	covid-19	JJ
cord-308279-gsk4qel5	41	11	pathogenesis	pathogenesis	NN
cord-308279-gsk4qel5	41	12	,	,	.
cord-308279-gsk4qel5	42	1	in	in	IN
cord-308279-gsk4qel5	42	2	which	which	WDT
cord-308279-gsk4qel5	42	3	a	a	DT
cord-308279-gsk4qel5	42	4	fragment	fragment	NN
cord-308279-gsk4qel5	42	5	or	or	CC
cord-308279-gsk4qel5	42	6	fragments	fragment	NNS
cord-308279-gsk4qel5	42	7	of	of	IN
cord-308279-gsk4qel5	42	8	SARS	SARS	NNP
cord-308279-gsk4qel5	42	9	-	-	HYPH
cord-308279-gsk4qel5	42	10	CoV-2	CoV-2	NNP
cord-308279-gsk4qel5	42	11	spike	spike	NN
cord-308279-gsk4qel5	42	12	protein	protein	NN
cord-308279-gsk4qel5	42	13	is	be	VBZ
cord-308279-gsk4qel5	42	14	/	/	,
cord-308279-gsk4qel5	42	15	are	be	VBP
cord-308279-gsk4qel5	42	16	released	release	VBN
cord-308279-gsk4qel5	42	17	into	into	IN
cord-308279-gsk4qel5	42	18	the	the	DT
cord-308279-gsk4qel5	42	19	patients	patient	NNS
cord-308279-gsk4qel5	42	20	'	'	POS
cord-308279-gsk4qel5	42	21	blood	blood	NN
cord-308279-gsk4qel5	42	22	circulation	circulation	NN
cord-308279-gsk4qel5	42	23	,	,	,
cord-308279-gsk4qel5	42	24	predisposing	predispose	VBG
cord-308279-gsk4qel5	42	25	patients	patient	NNS
cord-308279-gsk4qel5	42	26	with	with	IN
cord-308279-gsk4qel5	42	27	cardiovascular	cardiovascular	JJ
cord-308279-gsk4qel5	42	28	disease	disease	NN
cord-308279-gsk4qel5	42	29	conditions	condition	NNS
cord-308279-gsk4qel5	42	30	to	to	TO
cord-308279-gsk4qel5	42	31	severe	severe	JJ
cord-308279-gsk4qel5	42	32	COVID-19	covid-19	JJ
cord-308279-gsk4qel5	42	33	outcomes	outcome	NNS
cord-308279-gsk4qel5	42	34	.	.	.
cord-308279-gsk4qel5	43	1	Thus	thus	RB
cord-308279-gsk4qel5	43	2	,	,	,
cord-308279-gsk4qel5	43	3	COVID-19	covid-19	JJ
cord-308279-gsk4qel5	43	4	deaths	death	NNS
cord-308279-gsk4qel5	43	5	of	of	IN
cord-308279-gsk4qel5	43	6	patients	patient	NNS
cord-308279-gsk4qel5	43	7	with	with	IN
cord-308279-gsk4qel5	43	8	cardiovascular	cardiovascular	JJ
cord-308279-gsk4qel5	43	9	co	co	NN
cord-308279-gsk4qel5	43	10	-	-	NN
cord-308279-gsk4qel5	43	11	comorbidity	comorbidity	NN
cord-308279-gsk4qel5	43	12	are	be	VBP
cord-308279-gsk4qel5	43	13	due	due	JJ
cord-308279-gsk4qel5	43	14	to	to	IN
cord-308279-gsk4qel5	43	15	the	the	DT
cord-308279-gsk4qel5	43	16	death	death	NN
cord-308279-gsk4qel5	43	17	of	of	IN
cord-308279-gsk4qel5	43	18	host	host	NN
cord-308279-gsk4qel5	43	19	cells	cell	NNS
cord-308279-gsk4qel5	43	20	as	as	IN
cord-308279-gsk4qel5	43	21	a	a	DT
cord-308279-gsk4qel5	43	22	consequence	consequence	NN
cord-308279-gsk4qel5	43	23	of	of	IN
cord-308279-gsk4qel5	43	24	the	the	DT
cord-308279-gsk4qel5	43	25	viral	viral	JJ
cord-308279-gsk4qel5	43	26	infection	infection	NN
cord-308279-gsk4qel5	43	27	and	and	CC
cord-308279-gsk4qel5	43	28	replication	replication	NN
cord-308279-gsk4qel5	43	29	as	as	RB
cord-308279-gsk4qel5	43	30	well	well	RB
cord-308279-gsk4qel5	43	31	as	as	IN
cord-308279-gsk4qel5	43	32	the	the	DT
cord-308279-gsk4qel5	43	33	spike	spike	NN
cord-308279-gsk4qel5	43	34	protein	protein	NN
cord-308279-gsk4qel5	43	35	fragment	fragment	NN
cord-308279-gsk4qel5	43	36	-	-	HYPH
cord-308279-gsk4qel5	43	37	mediated	mediate	VBN
cord-308279-gsk4qel5	43	38	cell	cell	NN
cord-308279-gsk4qel5	43	39	signaling	signal	VBG
cord-308279-gsk4qel5	43	40	in	in	IN
cord-308279-gsk4qel5	43	41	human	human	JJ
cord-308279-gsk4qel5	43	42	host	host	NN
cord-308279-gsk4qel5	43	43	cardiovascular	cardiovascular	JJ
cord-308279-gsk4qel5	43	44	cells	cell	NNS
cord-308279-gsk4qel5	43	45	.	.	.
cord-308279-gsk4qel5	44	1	The	the	DT
cord-308279-gsk4qel5	44	2	current	current	JJ
cord-308279-gsk4qel5	44	3	focus	focus	NN
cord-308279-gsk4qel5	44	4	for	for	IN
cord-308279-gsk4qel5	44	5	developing	develop	VBG
cord-308279-gsk4qel5	44	6	therapeutic	therapeutic	JJ
cord-308279-gsk4qel5	44	7	strategies	strategy	NNS
cord-308279-gsk4qel5	44	8	against	against	IN
cord-308279-gsk4qel5	44	9	COVID-19	COVID-19	NNP
cord-308279-gsk4qel5	44	10	focuses	focus	NNS
cord-308279-gsk4qel5	44	11	on	on	IN
cord-308279-gsk4qel5	44	12	the	the	DT
cord-308279-gsk4qel5	44	13	vaccine	vaccine	NN
cord-308279-gsk4qel5	44	14	development	development	NN
cord-308279-gsk4qel5	44	15	and	and	CC
cord-308279-gsk4qel5	44	16	searching	search	VBG
cord-308279-gsk4qel5	44	17	for	for	IN
cord-308279-gsk4qel5	44	18	agents	agent	NNS
cord-308279-gsk4qel5	44	19	that	that	WDT
cord-308279-gsk4qel5	44	20	inhibit	inhibit	VBP
cord-308279-gsk4qel5	44	21	the	the	DT
cord-308279-gsk4qel5	44	22	viral	viral	JJ
cord-308279-gsk4qel5	44	23	replication	replication	NN
cord-308279-gsk4qel5	44	24	.	.	.
cord-308279-gsk4qel5	45	1	If	if	IN
cord-308279-gsk4qel5	45	2	my	-PRON-	PRP$
cord-308279-gsk4qel5	45	3	hypothesis	hypothesis	NN
cord-308279-gsk4qel5	45	4	is	be	VBZ
cord-308279-gsk4qel5	45	5	correct	correct	JJ
cord-308279-gsk4qel5	45	6	,	,	,
cord-308279-gsk4qel5	45	7	it	-PRON-	PRP
cord-308279-gsk4qel5	45	8	is	be	VBZ
cord-308279-gsk4qel5	45	9	critical	critical	JJ
cord-308279-gsk4qel5	45	10	to	to	TO
cord-308279-gsk4qel5	45	11	also	also	RB
cord-308279-gsk4qel5	45	12	inhibit	inhibit	VB
cord-308279-gsk4qel5	45	13	the	the	DT
cord-308279-gsk4qel5	45	14	unexpected	unexpected	JJ
cord-308279-gsk4qel5	45	15	biological	biological	JJ
cord-308279-gsk4qel5	45	16	events	event	NNS
cord-308279-gsk4qel5	45	17	that	that	WDT
cord-308279-gsk4qel5	45	18	are	be	VBP
cord-308279-gsk4qel5	45	19	elicited	elicit	VBN
cord-308279-gsk4qel5	45	20	by	by	IN
cord-308279-gsk4qel5	45	21	SARS	SARS	NNP
cord-308279-gsk4qel5	45	22	-	-	HYPH
cord-308279-gsk4qel5	45	23	CoV-2	CoV-2	NNP
cord-308279-gsk4qel5	45	24	such	such	JJ
cord-308279-gsk4qel5	45	25	as	as	IN
cord-308279-gsk4qel5	45	26	the	the	DT
cord-308279-gsk4qel5	45	27	release	release	NN
cord-308279-gsk4qel5	45	28	of	of	IN
cord-308279-gsk4qel5	45	29	spike	spike	NN
cord-308279-gsk4qel5	45	30	protein	protein	NN
cord-308279-gsk4qel5	45	31	fragments	fragment	NNS
cord-308279-gsk4qel5	45	32	that	that	WDT
cord-308279-gsk4qel5	45	33	affect	affect	VBP
cord-308279-gsk4qel5	45	34	cardiovascular	cardiovascular	JJ
cord-308279-gsk4qel5	45	35	cells	cell	NNS
cord-308279-gsk4qel5	45	36	in	in	IN
cord-308279-gsk4qel5	45	37	addition	addition	NN
cord-308279-gsk4qel5	45	38	to	to	IN
cord-308279-gsk4qel5	45	39	inhibiting	inhibit	VBG
cord-308279-gsk4qel5	45	40	the	the	DT
cord-308279-gsk4qel5	45	41	viral	viral	JJ
cord-308279-gsk4qel5	45	42	replication	replication	NN
cord-308279-gsk4qel5	45	43	in	in	IN
cord-308279-gsk4qel5	45	44	order	order	NN
cord-308279-gsk4qel5	45	45	to	to	TO
cord-308279-gsk4qel5	45	46	successfully	successfully	RB
cord-308279-gsk4qel5	45	47	reduce	reduce	VB
cord-308279-gsk4qel5	45	48	the	the	DT
cord-308279-gsk4qel5	45	49	mortality	mortality	NN
cord-308279-gsk4qel5	45	50	and	and	CC
cord-308279-gsk4qel5	45	51	morbidity	morbidity	NN
cord-308279-gsk4qel5	45	52	associated	associate	VBN
cord-308279-gsk4qel5	45	53	with	with	IN
cord-308279-gsk4qel5	45	54	COVID-19	COVID-19	NNP
cord-308279-gsk4qel5	45	55	and	and	CC
cord-308279-gsk4qel5	45	56	to	to	TO
cord-308279-gsk4qel5	45	57	end	end	VB
cord-308279-gsk4qel5	45	58	the	the	DT
cord-308279-gsk4qel5	45	59	pandemic	pandemic	NN
cord-308279-gsk4qel5	45	60	.	.	.
cord-308279-gsk4qel5	46	1	Epidemiology	epidemiology	NN
cord-308279-gsk4qel5	46	2	,	,	,
cord-308279-gsk4qel5	46	3	genetic	genetic	JJ
cord-308279-gsk4qel5	46	4	recombination	recombination	NN
cord-308279-gsk4qel5	46	5	,	,	,
cord-308279-gsk4qel5	46	6	and	and	CC
cord-308279-gsk4qel5	46	7	pathogenesis	pathogenesis	NN
cord-308279-gsk4qel5	46	8	of	of	IN
cord-308279-gsk4qel5	46	9	coronaviruses	coronaviruse	NNS
cord-308279-gsk4qel5	47	1	The	the	DT
cord-308279-gsk4qel5	47	2	molecular	molecular	JJ
cord-308279-gsk4qel5	47	3	biology	biology	NN
cord-308279-gsk4qel5	47	4	of	of	IN
cord-308279-gsk4qel5	47	5	SARS	SARS	NNP
cord-308279-gsk4qel5	47	6	coronavirus	coronavirus	NN
cord-308279-gsk4qel5	48	1	A	a	DT
cord-308279-gsk4qel5	48	2	new	new	JJ
cord-308279-gsk4qel5	48	3	coronavirus	coronavirus	NN
cord-308279-gsk4qel5	48	4	associated	associate	VBN
cord-308279-gsk4qel5	48	5	with	with	IN
cord-308279-gsk4qel5	48	6	human	human	JJ
cord-308279-gsk4qel5	48	7	respiratory	respiratory	JJ
cord-308279-gsk4qel5	48	8	disease	disease	NN
cord-308279-gsk4qel5	48	9	in	in	IN
cord-308279-gsk4qel5	48	10	China	China	NNP
cord-308279-gsk4qel5	48	11	Clinical	clinical	JJ
cord-308279-gsk4qel5	48	12	features	feature	NNS
cord-308279-gsk4qel5	48	13	of	of	IN
cord-308279-gsk4qel5	48	14	patients	patient	NNS
cord-308279-gsk4qel5	48	15	infected	infect	VBN
cord-308279-gsk4qel5	48	16	with	with	IN
cord-308279-gsk4qel5	48	17	2019	2019	CD
cord-308279-gsk4qel5	48	18	novel	novel	JJ
cord-308279-gsk4qel5	48	19	coronavirus	coronavirus	NN
cord-308279-gsk4qel5	48	20	in	in	IN
cord-308279-gsk4qel5	48	21	Wuhan	Wuhan	NNP
cord-308279-gsk4qel5	48	22	Structural	Structural	NNP
cord-308279-gsk4qel5	48	23	basis	basis	NN
cord-308279-gsk4qel5	48	24	for	for	IN
cord-308279-gsk4qel5	48	25	the	the	DT
cord-308279-gsk4qel5	48	26	recognition	recognition	NN
cord-308279-gsk4qel5	48	27	of	of	IN
cord-308279-gsk4qel5	48	28	SARS	SARS	NNP
cord-308279-gsk4qel5	48	29	-	-	HYPH
cord-308279-gsk4qel5	48	30	CoV-2	CoV-2	NNP
cord-308279-gsk4qel5	48	31	by	by	IN
cord-308279-gsk4qel5	48	32	full	full	JJ
cord-308279-gsk4qel5	48	33	-	-	HYPH
cord-308279-gsk4qel5	48	34	length	length	NN
cord-308279-gsk4qel5	48	35	human	human	JJ
cord-308279-gsk4qel5	48	36	ACE2	ACE2	NNP
cord-308279-gsk4qel5	48	37	Characterization	characterization	NN
cord-308279-gsk4qel5	48	38	of	of	IN
cord-308279-gsk4qel5	48	39	the	the	DT
cord-308279-gsk4qel5	48	40	receptor	receptor	NN
cord-308279-gsk4qel5	48	41	-	-	HYPH
cord-308279-gsk4qel5	48	42	binding	bind	VBG
cord-308279-gsk4qel5	48	43	domain	domain	NN
cord-308279-gsk4qel5	48	44	(	(	-LRB-
cord-308279-gsk4qel5	48	45	RBD	RBD	NNP
cord-308279-gsk4qel5	48	46	)	)	-RRB-
cord-308279-gsk4qel5	48	47	of	of	IN
cord-308279-gsk4qel5	48	48	2019	2019	CD
cord-308279-gsk4qel5	48	49	novel	novel	JJ
cord-308279-gsk4qel5	48	50	coronavirus	coronavirus	NN
cord-308279-gsk4qel5	48	51	:	:	:
cord-308279-gsk4qel5	48	52	implication	implication	NN
cord-308279-gsk4qel5	48	53	for	for	IN
cord-308279-gsk4qel5	48	54	development	development	NN
cord-308279-gsk4qel5	48	55	of	of	IN
cord-308279-gsk4qel5	48	56	RBD	RBD	NNP
cord-308279-gsk4qel5	48	57	protein	protein	NN
cord-308279-gsk4qel5	48	58	as	as	IN
cord-308279-gsk4qel5	48	59	a	a	DT
cord-308279-gsk4qel5	48	60	viral	viral	JJ
cord-308279-gsk4qel5	48	61	attachment	attachment	NN
cord-308279-gsk4qel5	48	62	inhibitor	inhibitor	NN
cord-308279-gsk4qel5	48	63	and	and	CC
cord-308279-gsk4qel5	48	64	vaccine	vaccine	NN
cord-308279-gsk4qel5	48	65	Pathological	pathological	JJ
cord-308279-gsk4qel5	48	66	findings	finding	NNS
cord-308279-gsk4qel5	48	67	of	of	IN
cord-308279-gsk4qel5	48	68	COVID-19	COVID-19	NNP
cord-308279-gsk4qel5	48	69	associated	associate	VBN
cord-308279-gsk4qel5	48	70	with	with	IN
cord-308279-gsk4qel5	48	71	acute	acute	JJ
cord-308279-gsk4qel5	48	72	respiratory	respiratory	JJ
cord-308279-gsk4qel5	48	73	distress	distress	NN
cord-308279-gsk4qel5	48	74	syndrome	syndrome	NN
cord-308279-gsk4qel5	48	75	Risk	risk	NN
cord-308279-gsk4qel5	48	76	factors	factor	NNS
cord-308279-gsk4qel5	48	77	associated	associate	VBN
cord-308279-gsk4qel5	48	78	with	with	IN
cord-308279-gsk4qel5	48	79	acute	acute	JJ
cord-308279-gsk4qel5	48	80	respiratory	respiratory	JJ
cord-308279-gsk4qel5	48	81	distress	distress	NN
cord-308279-gsk4qel5	48	82	syndrome	syndrome	NN
cord-308279-gsk4qel5	48	83	and	and	CC
cord-308279-gsk4qel5	48	84	death	death	NN
cord-308279-gsk4qel5	48	85	in	in	IN
cord-308279-gsk4qel5	48	86	patients	patient	NNS
cord-308279-gsk4qel5	48	87	with	with	IN
cord-308279-gsk4qel5	48	88	coronavirus	coronavirus	NN
cord-308279-gsk4qel5	48	89	disease	disease	NN
cord-308279-gsk4qel5	48	90	Prevalence	prevalence	NN
cord-308279-gsk4qel5	48	91	and	and	CC
cord-308279-gsk4qel5	48	92	impact	impact	NN
cord-308279-gsk4qel5	48	93	of	of	IN
cord-308279-gsk4qel5	48	94	cardiovascular	cardiovascular	JJ
cord-308279-gsk4qel5	48	95	metabolic	metabolic	JJ
cord-308279-gsk4qel5	48	96	diseases	disease	NNS
cord-308279-gsk4qel5	48	97	on	on	IN
cord-308279-gsk4qel5	48	98	COVID-19	COVID-19	NNP
cord-308279-gsk4qel5	48	99	in	in	IN
cord-308279-gsk4qel5	48	100	China	China	NNP
cord-308279-gsk4qel5	48	101	Prevalence	prevalence	NN
cord-308279-gsk4qel5	48	102	of	of	IN
cord-308279-gsk4qel5	48	103	comorbidities	comorbiditie	NNS
cord-308279-gsk4qel5	48	104	and	and	CC
cord-308279-gsk4qel5	48	105	its	-PRON-	PRP$
cord-308279-gsk4qel5	48	106	effects	effect	NNS
cord-308279-gsk4qel5	48	107	in	in	IN
cord-308279-gsk4qel5	48	108	patients	patient	NNS
cord-308279-gsk4qel5	48	109	infected	infect	VBN
cord-308279-gsk4qel5	48	110	with	with	IN
cord-308279-gsk4qel5	48	111	SARS	SARS	NNP
cord-308279-gsk4qel5	48	112	-	-	HYPH
cord-308279-gsk4qel5	48	113	CoV-2	CoV-2	NNP
cord-308279-gsk4qel5	48	114	:	:	:
cord-308279-gsk4qel5	48	115	A	a	DT
cord-308279-gsk4qel5	48	116	systematic	systematic	JJ
cord-308279-gsk4qel5	48	117	review	review	NN
cord-308279-gsk4qel5	48	118	and	and	CC
cord-308279-gsk4qel5	48	119	meta	meta	NNP
cord-308279-gsk4qel5	48	120	-	-	HYPH
cord-308279-gsk4qel5	48	121	analysis	analysis	NN
cord-308279-gsk4qel5	48	122	SARS	SARS	NNP
cord-308279-gsk4qel5	48	123	-	-	HYPH
cord-308279-gsk4qel5	48	124	CoV-2	CoV-2	NNP
cord-308279-gsk4qel5	48	125	spike	spike	NN
cord-308279-gsk4qel5	48	126	protein	protein	NN
cord-308279-gsk4qel5	48	127	-	-	HYPH
cord-308279-gsk4qel5	48	128	mediated	mediate	VBN
cord-308279-gsk4qel5	48	129	cell	cell	NN
cord-308279-gsk4qel5	48	130	signaling	signal	VBG
cord-308279-gsk4qel5	48	131	in	in	IN
cord-308279-gsk4qel5	48	132	lung	lung	NN
cord-308279-gsk4qel5	48	133	vascular	vascular	JJ
cord-308279-gsk4qel5	48	134	cells	cell	NNS
cord-308279-gsk4qel5	49	1	This	this	DT
cord-308279-gsk4qel5	49	2	work	work	NN
cord-308279-gsk4qel5	49	3	was	be	VBD
cord-308279-gsk4qel5	49	4	supported	support	VBN
cord-308279-gsk4qel5	49	5	in	in	IN
cord-308279-gsk4qel5	49	6	part	part	NN
cord-308279-gsk4qel5	49	7	by	by	IN
cord-308279-gsk4qel5	49	8	NIH	NIH	NNP
cord-308279-gsk4qel5	49	9	(	(	-LRB-
cord-308279-gsk4qel5	49	10	R21AI142649	R21AI142649	NNP
cord-308279-gsk4qel5	49	11	,	,	,
cord-308279-gsk4qel5	49	12	R03AG059554	R03AG059554	NNPS
cord-308279-gsk4qel5	49	13	,	,	,
cord-308279-gsk4qel5	49	14	and	and	CC
cord-308279-gsk4qel5	49	15	R03AA026516	R03AA026516	NNP
cord-308279-gsk4qel5	49	16	)	)	-RRB-
cord-308279-gsk4qel5	49	17	to	to	IN
cord-308279-gsk4qel5	49	18	Y.J.S.	Y.J.S.	NNP
cord-308279-gsk4qel5	50	1	The	the	DT
cord-308279-gsk4qel5	50	2	content	content	NN
cord-308279-gsk4qel5	50	3	is	be	VBZ
cord-308279-gsk4qel5	50	4	solely	solely	RB
cord-308279-gsk4qel5	50	5	the	the	DT
cord-308279-gsk4qel5	50	6	responsibility	responsibility	NN
cord-308279-gsk4qel5	50	7	of	of	IN
cord-308279-gsk4qel5	50	8	the	the	DT
cord-308279-gsk4qel5	50	9	authors	author	NNS
cord-308279-gsk4qel5	50	10	and	and	CC
cord-308279-gsk4qel5	50	11	does	do	VBZ
cord-308279-gsk4qel5	50	12	not	not	RB
cord-308279-gsk4qel5	50	13	necessarily	necessarily	RB
cord-308279-gsk4qel5	50	14	represent	represent	VB
cord-308279-gsk4qel5	50	15	the	the	DT
cord-308279-gsk4qel5	50	16	official	official	JJ
cord-308279-gsk4qel5	50	17	views	view	NNS
cord-308279-gsk4qel5	50	18	of	of	IN
cord-308279-gsk4qel5	50	19	the	the	DT
cord-308279-gsk4qel5	50	20	NIH	NIH	NNP
cord-308279-gsk4qel5	50	21	.	.	.
cord-308279-gsk4qel5	51	1	The	the	DT
cord-308279-gsk4qel5	51	2	author	author	NN
cord-308279-gsk4qel5	51	3	has	have	VBZ
cord-308279-gsk4qel5	51	4	no	no	DT
cord-308279-gsk4qel5	51	5	conflict	conflict	NN
cord-308279-gsk4qel5	51	6	of	of	IN
cord-308279-gsk4qel5	51	7	interest	interest	NN
cord-308279-gsk4qel5	51	8	.	.	.