id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-338585-ep9r1n8t	Perrin, David M.	A hypothesis for examining dihydroxyacetone, the active component in self-tanning products, as a topical prophylactic against SARS-COV-2 transmission	2020-09-16		.txt	text/plain	1800	84	42	title: A hypothesis for examining dihydroxyacetone, the active component in self-tanning products, as a topical prophylactic against SARS-COV-2 transmission This hypothesis raises the interesting prospect that dihydroxyacetone (DHA), the key ingredient in self-tanning creams, when applied daily to the face and hands may have prophylactic action against SARS-COV-2 transmission and infection. The Maillard Reaction, comprises a manifold of reactions including Schiff-base formation, aldol-type condensations, Amadori rearrangements, and dehydrative and/or oxidative aromatization events that modify lysine amines and give rise to crosslinks, (12) which are consistent with other advanced glycation events seen in diabetic patients. Together, such studies would systematically advance this hypothesis from well-established in vitro results to an easily monitored clinical trial, that would lead to a medically justified recommendation for daily topical prophylactic application of DHA to the face and hands for reducing SARS-COV-2 infection.	./cache/cord-338585-ep9r1n8t.txt	./txt/cord-338585-ep9r1n8t.txt