id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-301619-0ojayw16	Adamowicz, Jan	May patients receiving 5-alpha-reductase inhibitors be in higher risk of COVID-19 complications ?	2020-04-22		.txt	text/plain	1203	76	36	Based on this observation, our proposed hypothesis is that 5-alpha-reductase inhibitors, that are commonly used for BPH treatment, may be one of the factors contributing to poorer prognosis in males. Based on this observation, our proposed hypothesis is that 5-alpha-reductase inhibitors, that are commonly used for BPH treatment, may be one of the factors contributing to poorer prognosis in males. Consequently, we introduce hypothesis that 5-alpha-reductase inhibitors may disrupt androgens metabolism in lungs, which in turn may have a negative impact on course of COVID-19 infection. Under this assumption, 5-alpha-reductase inhibitors might increase androgen concentration in lungs hampering their regeneration. Due to high prevalence of 5-alpha-reductase inhibitor in BPH treatment, its potential negative influence on recovery after COVID-19 infection, should be established. According to presented hypothesis, patients receiving 5-alpha-reductase inhibitors, might be vulnerable to COVID-19 infection with poorer prognosis. May patients receiving 5 alpha-reductase inhibitors be in higher risk of COVID-19 complications	./cache/cord-301619-0ojayw16.txt	./txt/cord-301619-0ojayw16.txt