id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-277931-3hxhsmw8	Khitan, Zeid J.	SCan Charcoal Improve Outcomes in COVID-19 Infections?	2020-08-10		.txt	text/plain	1090	60	44	We propose to examine the potential utility of oral activated charcoal with the hypothesis that such treatment would lower absorption of microbiome derived toxins and ameliorate systemic oxidant stress and inflammation. We propose to examine the potential utility of oral activated charcoal with the hypothesis that such treatment would lower absorption of microbiome derived toxins and ameliorate systemic oxidant stress and inflammation. It appears that age, renal dysfunction and obesity are amongst the most important risk factors for serious or fatal COVID-19 infection 3, 4 . To test this hypothesis, we would suggest first a proof of concept study where a relatively small group of patients at high risk for COVID-19 complications are given activated charcoal at doses similar to that used in previous renal failure studies 18, 19 when the diagnosis is first made. Uremic Toxins Activates Na/K-ATPase Oxidant Amplification Loop Causing Phenotypic Changes in Adipocytes in In Vitro Models Protein-bound uremic toxins, inflammation and oxidative stress: a cross-sectional study in stage 3-4 chronic kidney disease	./cache/cord-277931-3hxhsmw8.txt	./txt/cord-277931-3hxhsmw8.txt