id author title date pages extension mime words sentences flesch summary cache txt cord-265724-fdt00qw1 Varadarajan, Saranya EMMPRIN/BASIGIN as a biological modulator of oral cancer and COVID-19 interaction: novel propositions 2020-07-09 .txt text/plain 1761 105 39 Apart from ACE-2, recently EMMPRIN, has been regarded as a target for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) attachment and entry into the host cell. Since one of the routes of entry for the virus is the oral cavity, it becomes imperative to percept oral comorbidities such oral squamous cell carcinoma (OSCC) and oral potentially malignant disorders (OPMDs) in terms of EMMPRIN as a target for SARS-CoV-2. 1 Angiotensin-Converting Enzyme 2 (ACE-2) on the host cells is the attachment protein for the spike receptor present on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). [4] [5] [6] Apart from ACE-2, recently extracellular matrix metalloproteinase inducer (EMMPRIN), which is also called BASIGIN/CD147, has been regarded as a target for SARS-CoV-2 attachment and its entry into the host cell. OSCC, by the virtue of upregulation of EMMPRIN expression (potential and alternative site for 'S' receptor), increases the susceptibility to SARS-CoV-2 infection. ./cache/cord-265724-fdt00qw1.txt ./txt/cord-265724-fdt00qw1.txt