id sid tid token lemma pos cord-260087-9o9tb28h 1 1 key key NN cord-260087-9o9tb28h 1 2 : : : cord-260087-9o9tb28h 2 1 cord-260087 cord-260087 NNP cord-260087-9o9tb28h 2 2 - - HYPH cord-260087-9o9tb28h 2 3 9o9tb28h 9o9tb28h JJ cord-260087-9o9tb28h 2 4 authors author NNS cord-260087-9o9tb28h 2 5 : : : cord-260087-9o9tb28h 2 6 Furmanski Furmanski NNP cord-260087-9o9tb28h 2 7 , , , cord-260087-9o9tb28h 2 8 Martin Martin NNP cord-260087-9o9tb28h 2 9 title title NN cord-260087-9o9tb28h 2 10 : : : cord-260087-9o9tb28h 2 11 The the DT cord-260087-9o9tb28h 2 12 1977 1977 CD cord-260087-9o9tb28h 2 13 H1N1 H1N1 NNP cord-260087-9o9tb28h 2 14 Influenza Influenza NNP cord-260087-9o9tb28h 2 15 Virus virus NN cord-260087-9o9tb28h 2 16 Reemergence reemergence NN cord-260087-9o9tb28h 2 17 Demonstrated demonstrate VBD cord-260087-9o9tb28h 2 18 Gain gain NN cord-260087-9o9tb28h 2 19 - - HYPH cord-260087-9o9tb28h 2 20 of of IN cord-260087-9o9tb28h 2 21 - - HYPH cord-260087-9o9tb28h 2 22 Function function NN cord-260087-9o9tb28h 2 23 Hazards hazard NNS cord-260087-9o9tb28h 2 24 date date NN cord-260087-9o9tb28h 2 25 : : : cord-260087-9o9tb28h 2 26 2015 2015 CD cord-260087-9o9tb28h 2 27 - - HYPH cord-260087-9o9tb28h 2 28 09 09 CD cord-260087-9o9tb28h 2 29 - - SYM cord-260087-9o9tb28h 2 30 29 29 CD cord-260087-9o9tb28h 2 31 journal journal NN cord-260087-9o9tb28h 2 32 : : : cord-260087-9o9tb28h 3 1 mBio mbio NN cord-260087-9o9tb28h 3 2 DOI doi NN cord-260087-9o9tb28h 3 3 : : : cord-260087-9o9tb28h 4 1 10.1128 10.1128 CD cord-260087-9o9tb28h 4 2 / / SYM cord-260087-9o9tb28h 4 3 mbio.01434 mbio.01434 NNP cord-260087-9o9tb28h 4 4 - - HYPH cord-260087-9o9tb28h 4 5 15 15 CD cord-260087-9o9tb28h 4 6 sha sha NN cord-260087-9o9tb28h 4 7 : : : cord-260087-9o9tb28h 4 8 fa3906f048a58d703a5baff91a6545518cbcf4b7 fa3906f048a58d703a5baff91a6545518cbcf4b7 NNP cord-260087-9o9tb28h 4 9 doc_id doc_id CD cord-260087-9o9tb28h 4 10 : : : cord-260087-9o9tb28h 4 11 260087 260087 CD cord-260087-9o9tb28h 4 12 cord_uid cord_uid NNS cord-260087-9o9tb28h 4 13 : : : cord-260087-9o9tb28h 5 1 9o9tb28h 9o9tb28h NNP cord-260087-9o9tb28h 5 2 nan nan NNP cord-260087-9o9tb28h 5 3 R R NNP cord-260087-9o9tb28h 5 4 ozo ozo NNP cord-260087-9o9tb28h 5 5 and and CC cord-260087-9o9tb28h 5 6 Gronvall Gronvall NNP cord-260087-9o9tb28h 5 7 , , , cord-260087-9o9tb28h 5 8 in in IN cord-260087-9o9tb28h 5 9 " " `` cord-260087-9o9tb28h 5 10 The the DT cord-260087-9o9tb28h 5 11 Reemergent Reemergent NNP cord-260087-9o9tb28h 5 12 1977 1977 CD cord-260087-9o9tb28h 5 13 H1N1 H1N1 NNP cord-260087-9o9tb28h 5 14 Strain Strain NNP cord-260087-9o9tb28h 5 15 and and CC cord-260087-9o9tb28h 5 16 the the DT cord-260087-9o9tb28h 5 17 Gain gain NN cord-260087-9o9tb28h 5 18 - - HYPH cord-260087-9o9tb28h 5 19 of of IN cord-260087-9o9tb28h 5 20 - - HYPH cord-260087-9o9tb28h 5 21 Function function NN cord-260087-9o9tb28h 5 22 Debate debate NN cord-260087-9o9tb28h 5 23 " " '' cord-260087-9o9tb28h 5 24 ( ( -LRB- cord-260087-9o9tb28h 5 25 1 1 CD cord-260087-9o9tb28h 5 26 ) ) -RRB- cord-260087-9o9tb28h 5 27 , , , cord-260087-9o9tb28h 5 28 confirmed confirm VBD cord-260087-9o9tb28h 5 29 the the DT cord-260087-9o9tb28h 5 30 laboratory laboratory NN cord-260087-9o9tb28h 5 31 origin origin NN cord-260087-9o9tb28h 5 32 of of IN cord-260087-9o9tb28h 5 33 the the DT cord-260087-9o9tb28h 5 34 1977 1977 CD cord-260087-9o9tb28h 5 35 influenza influenza NN cord-260087-9o9tb28h 5 36 pandemic pandemic NN cord-260087-9o9tb28h 5 37 and and CC cord-260087-9o9tb28h 5 38 judged judge VBD cord-260087-9o9tb28h 5 39 it -PRON- PRP cord-260087-9o9tb28h 5 40 was be VBD cord-260087-9o9tb28h 5 41 unintentional unintentional JJ cord-260087-9o9tb28h 5 42 , , , cord-260087-9o9tb28h 5 43 but but CC cord-260087-9o9tb28h 5 44 they -PRON- PRP cord-260087-9o9tb28h 5 45 concluded conclude VBD cord-260087-9o9tb28h 5 46 that that IN cord-260087-9o9tb28h 5 47 its -PRON- PRP$ cord-260087-9o9tb28h 5 48 " " `` cord-260087-9o9tb28h 5 49 relevance relevance NN cord-260087-9o9tb28h 5 50 to to IN cord-260087-9o9tb28h 5 51 GoF GoF NNP cord-260087-9o9tb28h 5 52 research research NN cord-260087-9o9tb28h 5 53 is be VBZ cord-260087-9o9tb28h 5 54 greatly greatly RB cord-260087-9o9tb28h 5 55 diminished diminish VBN cord-260087-9o9tb28h 5 56 if if IN cord-260087-9o9tb28h 5 57 the the DT cord-260087-9o9tb28h 5 58 1977 1977 CD cord-260087-9o9tb28h 5 59 epidemic epidemic NN cord-260087-9o9tb28h 5 60 was be VBD cord-260087-9o9tb28h 5 61 the the DT cord-260087-9o9tb28h 5 62 result result NN cord-260087-9o9tb28h 5 63 of of IN cord-260087-9o9tb28h 5 64 a a DT cord-260087-9o9tb28h 5 65 vaccine vaccine NN cord-260087-9o9tb28h 5 66 trial trial NN cord-260087-9o9tb28h 5 67 or or CC cord-260087-9o9tb28h 5 68 vaccine vaccine NN cord-260087-9o9tb28h 5 69 development development NN cord-260087-9o9tb28h 5 70 gone go VBN cord-260087-9o9tb28h 5 71 awry awry JJ cord-260087-9o9tb28h 5 72 ; ; : cord-260087-9o9tb28h 5 73 these these DT cord-260087-9o9tb28h 5 74 are be VBP cord-260087-9o9tb28h 5 75 both both DT cord-260087-9o9tb28h 5 76 more more RBR cord-260087-9o9tb28h 5 77 plausible plausible JJ cord-260087-9o9tb28h 5 78 explanations explanation NNS cord-260087-9o9tb28h 5 79 than than IN cord-260087-9o9tb28h 5 80 a a DT cord-260087-9o9tb28h 5 81 single single JJ cord-260087-9o9tb28h 5 82 laboratory laboratory NN cord-260087-9o9tb28h 5 83 accident accident NN cord-260087-9o9tb28h 5 84 . . . cord-260087-9o9tb28h 6 1 " " `` cord-260087-9o9tb28h 6 2 Separating separate VBG cord-260087-9o9tb28h 6 3 the the DT cord-260087-9o9tb28h 6 4 risks risk NNS cord-260087-9o9tb28h 6 5 of of IN cord-260087-9o9tb28h 6 6 vaccine vaccine NN cord-260087-9o9tb28h 6 7 development development NN cord-260087-9o9tb28h 6 8 from from IN cord-260087-9o9tb28h 6 9 those those DT cord-260087-9o9tb28h 6 10 of of IN cord-260087-9o9tb28h 6 11 basic basic JJ cord-260087-9o9tb28h 6 12 gain gain NN cord-260087-9o9tb28h 6 13 - - HYPH cord-260087-9o9tb28h 6 14 of of IN cord-260087-9o9tb28h 6 15 - - HYPH cord-260087-9o9tb28h 6 16 function function NN cord-260087-9o9tb28h 6 17 ( ( -LRB- cord-260087-9o9tb28h 6 18 GoF GoF NNP cord-260087-9o9tb28h 6 19 ) ) -RRB- cord-260087-9o9tb28h 6 20 research research NN cord-260087-9o9tb28h 6 21 is be VBZ cord-260087-9o9tb28h 6 22 inappropriate inappropriate JJ cord-260087-9o9tb28h 6 23 , , , cord-260087-9o9tb28h 6 24 because because IN cord-260087-9o9tb28h 6 25 GoF GoF NNP cord-260087-9o9tb28h 6 26 research research NNP cord-260087-9o9tb28h 6 27 seeks seek VBZ cord-260087-9o9tb28h 6 28 to to TO cord-260087-9o9tb28h 6 29 discover discover VB cord-260087-9o9tb28h 6 30 antigenic antigenic JJ cord-260087-9o9tb28h 6 31 and and CC cord-260087-9o9tb28h 6 32 genomic genomic JJ cord-260087-9o9tb28h 6 33 changes change NNS cord-260087-9o9tb28h 6 34 that that WDT cord-260087-9o9tb28h 6 35 facilitate facilitate VBP cord-260087-9o9tb28h 6 36 human human NN cord-260087-9o9tb28h 6 37 - - HYPH cord-260087-9o9tb28h 6 38 to to IN cord-260087-9o9tb28h 6 39 - - HYPH cord-260087-9o9tb28h 6 40 human human JJ cord-260087-9o9tb28h 6 41 transmission transmission NN cord-260087-9o9tb28h 6 42 and/or and/or CC cord-260087-9o9tb28h 6 43 augment augment VB cord-260087-9o9tb28h 6 44 virulence virulence NN cord-260087-9o9tb28h 6 45 , , , cord-260087-9o9tb28h 6 46 with with IN cord-260087-9o9tb28h 6 47 the the DT cord-260087-9o9tb28h 6 48 aim aim NN cord-260087-9o9tb28h 6 49 of of IN cord-260087-9o9tb28h 6 50 preemptively preemptively RB cord-260087-9o9tb28h 6 51 producing produce VBG cord-260087-9o9tb28h 6 52 vaccines vaccine NNS cord-260087-9o9tb28h 6 53 . . . cord-260087-9o9tb28h 7 1 Clearly clearly RB cord-260087-9o9tb28h 7 2 , , , cord-260087-9o9tb28h 7 3 if if IN cord-260087-9o9tb28h 7 4 and and CC cord-260087-9o9tb28h 7 5 when when WRB cord-260087-9o9tb28h 7 6 such such JJ cord-260087-9o9tb28h 7 7 changes change NNS cord-260087-9o9tb28h 7 8 are be VBP cord-260087-9o9tb28h 7 9 identified identify VBN cord-260087-9o9tb28h 7 10 , , , cord-260087-9o9tb28h 7 11 candidate candidate NN cord-260087-9o9tb28h 7 12 viruses virus NNS cord-260087-9o9tb28h 7 13 possessing possess VBG cord-260087-9o9tb28h 7 14 novel novel JJ cord-260087-9o9tb28h 7 15 potential potential JJ cord-260087-9o9tb28h 7 16 pandemic pandemic NN cord-260087-9o9tb28h 7 17 traits trait NNS cord-260087-9o9tb28h 7 18 would would MD cord-260087-9o9tb28h 7 19 be be VB cord-260087-9o9tb28h 7 20 sent send VBN cord-260087-9o9tb28h 7 21 to to IN cord-260087-9o9tb28h 7 22 vaccine vaccine NN cord-260087-9o9tb28h 7 23 laboratories laboratory NNS cord-260087-9o9tb28h 7 24 for for IN cord-260087-9o9tb28h 7 25 further further JJ cord-260087-9o9tb28h 7 26 development development NN cord-260087-9o9tb28h 7 27 , , , cord-260087-9o9tb28h 7 28 prior prior RB cord-260087-9o9tb28h 7 29 to to IN cord-260087-9o9tb28h 7 30 their -PRON- PRP$ cord-260087-9o9tb28h 7 31 appearance appearance NN cord-260087-9o9tb28h 7 32 in in IN cord-260087-9o9tb28h 7 33 nature nature NN cord-260087-9o9tb28h 7 34 . . . cord-260087-9o9tb28h 8 1 Because because IN cord-260087-9o9tb28h 8 2 it -PRON- PRP cord-260087-9o9tb28h 8 3 is be VBZ cord-260087-9o9tb28h 8 4 unlikely unlikely JJ cord-260087-9o9tb28h 8 5 that that IN cord-260087-9o9tb28h 8 6 such such JJ cord-260087-9o9tb28h 8 7 traits trait NNS cord-260087-9o9tb28h 8 8 would would MD cord-260087-9o9tb28h 8 9 be be VB cord-260087-9o9tb28h 8 10 unique unique JJ cord-260087-9o9tb28h 8 11 , , , cord-260087-9o9tb28h 8 12 and and CC cord-260087-9o9tb28h 8 13 because because IN cord-260087-9o9tb28h 8 14 the the DT cord-260087-9o9tb28h 8 15 natural natural JJ cord-260087-9o9tb28h 8 16 appearance appearance NN cord-260087-9o9tb28h 8 17 of of IN cord-260087-9o9tb28h 8 18 any any DT cord-260087-9o9tb28h 8 19 particular particular JJ cord-260087-9o9tb28h 8 20 trait trait NN cord-260087-9o9tb28h 8 21 is be VBZ cord-260087-9o9tb28h 8 22 unpredictable unpredictable JJ cord-260087-9o9tb28h 8 23 , , , cord-260087-9o9tb28h 8 24 a a DT cord-260087-9o9tb28h 8 25 stable stable NN cord-260087-9o9tb28h 8 26 of of IN cord-260087-9o9tb28h 8 27 multiple multiple JJ cord-260087-9o9tb28h 8 28 potentially potentially RB cord-260087-9o9tb28h 8 29 pandemic pandemic JJ cord-260087-9o9tb28h 8 30 virus virus NN cord-260087-9o9tb28h 8 31 lineages lineage NNS cord-260087-9o9tb28h 8 32 , , , cord-260087-9o9tb28h 8 33 and and CC cord-260087-9o9tb28h 8 34 artificial artificial JJ cord-260087-9o9tb28h 8 35 hybrids hybrid NNS cord-260087-9o9tb28h 8 36 thereof thereof RB cord-260087-9o9tb28h 8 37 , , , cord-260087-9o9tb28h 8 38 could could MD cord-260087-9o9tb28h 8 39 enter enter VB cord-260087-9o9tb28h 8 40 the the DT cord-260087-9o9tb28h 8 41 vaccine vaccine NN cord-260087-9o9tb28h 8 42 development development NN cord-260087-9o9tb28h 8 43 laboratories laboratory NNS cord-260087-9o9tb28h 8 44 , , , cord-260087-9o9tb28h 8 45 multiplying multiply VBG cord-260087-9o9tb28h 8 46 the the DT cord-260087-9o9tb28h 8 47 opportunities opportunity NNS cord-260087-9o9tb28h 8 48 for for IN cord-260087-9o9tb28h 8 49 novel novel NN cord-260087-9o9tb28h 8 50 GoF GoF NNP cord-260087-9o9tb28h 8 51 viruses virus NNS cord-260087-9o9tb28h 8 52 to to TO cord-260087-9o9tb28h 8 53 escape escape VB cord-260087-9o9tb28h 8 54 . . . cord-260087-9o9tb28h 9 1 This this DT cord-260087-9o9tb28h 9 2 emphasizes emphasize VBZ cord-260087-9o9tb28h 9 3 rather rather RB cord-260087-9o9tb28h 9 4 than than IN cord-260087-9o9tb28h 9 5 diminishes diminish VBZ cord-260087-9o9tb28h 9 6 the the DT cord-260087-9o9tb28h 9 7 implications implication NNS cord-260087-9o9tb28h 9 8 of of IN cord-260087-9o9tb28h 9 9 the the DT cord-260087-9o9tb28h 9 10 1977 1977 CD cord-260087-9o9tb28h 9 11 H1N1 H1N1 NNP cord-260087-9o9tb28h 9 12 escape escape NN cord-260087-9o9tb28h 9 13 , , , cord-260087-9o9tb28h 9 14 since since IN cord-260087-9o9tb28h 9 15 the the DT cord-260087-9o9tb28h 9 16 1949 1949 CD cord-260087-9o9tb28h 9 17 - - SYM cord-260087-9o9tb28h 9 18 1950 1950 CD cord-260087-9o9tb28h 9 19 H1N1 H1N1 NNP cord-260087-9o9tb28h 9 20 virus virus NN cord-260087-9o9tb28h 9 21 progenitor progenitor NN cord-260087-9o9tb28h 9 22 of of IN cord-260087-9o9tb28h 9 23 the the DT cord-260087-9o9tb28h 9 24 1977 1977 CD cord-260087-9o9tb28h 9 25 virus virus NN cord-260087-9o9tb28h 9 26 was be VBD cord-260087-9o9tb28h 9 27 likely likely JJ cord-260087-9o9tb28h 9 28 in in IN cord-260087-9o9tb28h 9 29 vaccine vaccine NN cord-260087-9o9tb28h 9 30 development development NN cord-260087-9o9tb28h 9 31 preemptively preemptively RB cord-260087-9o9tb28h 9 32 because because IN cord-260087-9o9tb28h 9 33 of of IN cord-260087-9o9tb28h 9 34 the the DT cord-260087-9o9tb28h 9 35 unrealized unrealized JJ cord-260087-9o9tb28h 9 36 1976 1976 CD cord-260087-9o9tb28h 9 37 threat threat NN cord-260087-9o9tb28h 9 38 of of IN cord-260087-9o9tb28h 9 39 a a DT cord-260087-9o9tb28h 9 40 swine swine NN cord-260087-9o9tb28h 9 41 flu flu NN cord-260087-9o9tb28h 9 42 pandemic pandemic NN cord-260087-9o9tb28h 9 43 . . . cord-260087-9o9tb28h 10 1 I -PRON- PRP cord-260087-9o9tb28h 10 2 disagree disagree VBP cord-260087-9o9tb28h 10 3 with with IN cord-260087-9o9tb28h 10 4 the the DT cord-260087-9o9tb28h 10 5 authors author NNS cord-260087-9o9tb28h 10 6 ' ' POS cord-260087-9o9tb28h 10 7 statement statement NN cord-260087-9o9tb28h 10 8 : : : cord-260087-9o9tb28h 10 9 " " `` cord-260087-9o9tb28h 10 10 it -PRON- PRP cord-260087-9o9tb28h 10 11 remains remain VBZ cord-260087-9o9tb28h 10 12 likely likely JJ cord-260087-9o9tb28h 10 13 that that IN cord-260087-9o9tb28h 10 14 to to IN cord-260087-9o9tb28h 10 15 this this DT cord-260087-9o9tb28h 10 16 date date NN cord-260087-9o9tb28h 10 17 , , , cord-260087-9o9tb28h 10 18 there there EX cord-260087-9o9tb28h 10 19 has have VBZ cord-260087-9o9tb28h 10 20 been be VBN cord-260087-9o9tb28h 10 21 no no DT cord-260087-9o9tb28h 10 22 real real JJ cord-260087-9o9tb28h 10 23 - - HYPH cord-260087-9o9tb28h 10 24 world world NN cord-260087-9o9tb28h 10 25 example example NN cord-260087-9o9tb28h 10 26 of of IN cord-260087-9o9tb28h 10 27 a a DT cord-260087-9o9tb28h 10 28 laboratory laboratory NN cord-260087-9o9tb28h 10 29 accident accident NN cord-260087-9o9tb28h 10 30 that that WDT cord-260087-9o9tb28h 10 31 has have VBZ cord-260087-9o9tb28h 10 32 led lead VBN cord-260087-9o9tb28h 10 33 to to IN cord-260087-9o9tb28h 10 34 a a DT cord-260087-9o9tb28h 10 35 global global JJ cord-260087-9o9tb28h 10 36 epidemic epidemic NN cord-260087-9o9tb28h 10 37 . . . cord-260087-9o9tb28h 11 1 " " '' cord-260087-9o9tb28h 12 1 The the DT cord-260087-9o9tb28h 12 2 1977 1977 CD cord-260087-9o9tb28h 12 3 H1N1 H1N1 NNP cord-260087-9o9tb28h 12 4 virus virus NN cord-260087-9o9tb28h 12 5 caused cause VBD cord-260087-9o9tb28h 12 6 a a DT cord-260087-9o9tb28h 12 7 global global JJ cord-260087-9o9tb28h 12 8 epidemic epidemic NN cord-260087-9o9tb28h 12 9 , , , cord-260087-9o9tb28h 12 10 and and CC cord-260087-9o9tb28h 12 11 as as IN cord-260087-9o9tb28h 12 12 Rozo Rozo NNP cord-260087-9o9tb28h 12 13 and and CC cord-260087-9o9tb28h 12 14 Gronvall Gronvall NNP cord-260087-9o9tb28h 12 15 themselves -PRON- PRP cord-260087-9o9tb28h 12 16 concluded conclude VBD cord-260087-9o9tb28h 12 17 , , , cord-260087-9o9tb28h 12 18 it -PRON- PRP cord-260087-9o9tb28h 12 19 originated originate VBD cord-260087-9o9tb28h 12 20 in in IN cord-260087-9o9tb28h 12 21 a a DT cord-260087-9o9tb28h 12 22 microbiology microbiology NN cord-260087-9o9tb28h 12 23 laboratory laboratory NN cord-260087-9o9tb28h 12 24 and and CC cord-260087-9o9tb28h 12 25 its -PRON- PRP$ cord-260087-9o9tb28h 12 26 release release NN cord-260087-9o9tb28h 12 27 was be VBD cord-260087-9o9tb28h 12 28 unintentional unintentional JJ cord-260087-9o9tb28h 12 29 . . . cord-260087-9o9tb28h 13 1 Which which WDT cord-260087-9o9tb28h 13 2 laboratory laboratory NN cord-260087-9o9tb28h 13 3 is be VBZ cord-260087-9o9tb28h 13 4 responsible responsible JJ cord-260087-9o9tb28h 13 5 matters matter NNS cord-260087-9o9tb28h 13 6 little little JJ cord-260087-9o9tb28h 13 7 in in IN cord-260087-9o9tb28h 13 8 the the DT cord-260087-9o9tb28h 13 9 GoF GoF NNP cord-260087-9o9tb28h 13 10 debate debate NN cord-260087-9o9tb28h 13 11 . . . cord-260087-9o9tb28h 14 1 Rozo Rozo NNP cord-260087-9o9tb28h 14 2 and and CC cord-260087-9o9tb28h 14 3 Gronvall Gronvall NNP cord-260087-9o9tb28h 14 4 also also RB cord-260087-9o9tb28h 14 5 stated state VBD cord-260087-9o9tb28h 14 6 that that IN cord-260087-9o9tb28h 14 7 , , , cord-260087-9o9tb28h 14 8 " " `` cord-260087-9o9tb28h 14 9 in in IN cord-260087-9o9tb28h 14 10 1977 1977 CD cord-260087-9o9tb28h 14 11 , , , cord-260087-9o9tb28h 14 12 influenza influenza NN cord-260087-9o9tb28h 14 13 research research NN cord-260087-9o9tb28h 14 14 was be VBD cord-260087-9o9tb28h 14 15 performed perform VBN cord-260087-9o9tb28h 14 16 without without IN cord-260087-9o9tb28h 14 17 modern modern JJ cord-260087-9o9tb28h 14 18 biosafety biosafety NN cord-260087-9o9tb28h 14 19 regulations regulation NNS cord-260087-9o9tb28h 14 20 and and CC cord-260087-9o9tb28h 14 21 protective protective JJ cord-260087-9o9tb28h 14 22 equipment equipment NN cord-260087-9o9tb28h 14 23 , , , cord-260087-9o9tb28h 14 24 making make VBG cord-260087-9o9tb28h 14 25 the the DT cord-260087-9o9tb28h 14 26 lab lab NN cord-260087-9o9tb28h 14 27 accident accident NN cord-260087-9o9tb28h 14 28 hypothesis hypothesis NN cord-260087-9o9tb28h 14 29 much much RB cord-260087-9o9tb28h 14 30 less less RBR cord-260087-9o9tb28h 14 31 relevant relevant JJ cord-260087-9o9tb28h 14 32 to to IN cord-260087-9o9tb28h 14 33 the the DT cord-260087-9o9tb28h 14 34 modern modern JJ cord-260087-9o9tb28h 14 35 GoF GoF NNP cord-260087-9o9tb28h 14 36 debate debate NN cord-260087-9o9tb28h 14 37 . . . cord-260087-9o9tb28h 14 38 " " '' cord-260087-9o9tb28h 15 1 However however RB cord-260087-9o9tb28h 15 2 , , , cord-260087-9o9tb28h 15 3 the the DT cord-260087-9o9tb28h 15 4 current current JJ cord-260087-9o9tb28h 15 5 record record NN cord-260087-9o9tb28h 15 6 of of IN cord-260087-9o9tb28h 15 7 containment containment NN cord-260087-9o9tb28h 15 8 of of IN cord-260087-9o9tb28h 15 9 high high JJ cord-260087-9o9tb28h 15 10 - - HYPH cord-260087-9o9tb28h 15 11 consequence consequence NN cord-260087-9o9tb28h 15 12 pathogens pathogen NNS cord-260087-9o9tb28h 15 13 is be VBZ cord-260087-9o9tb28h 15 14 hardly hardly RB cord-260087-9o9tb28h 15 15 reassuring reassuring JJ cord-260087-9o9tb28h 15 16 . . . cord-260087-9o9tb28h 16 1 My -PRON- PRP$ cord-260087-9o9tb28h 16 2 review review NN cord-260087-9o9tb28h 16 3 of of IN cord-260087-9o9tb28h 16 4 11 11 CD cord-260087-9o9tb28h 16 5 relevant relevant JJ cord-260087-9o9tb28h 16 6 events event NNS cord-260087-9o9tb28h 16 7 ( ( -LRB- cord-260087-9o9tb28h 16 8 2 2 CD cord-260087-9o9tb28h 16 9 ) ) -RRB- cord-260087-9o9tb28h 16 10 found find VBD cord-260087-9o9tb28h 16 11 that that IN cord-260087-9o9tb28h 16 12 escapes escape NNS cord-260087-9o9tb28h 16 13 of of IN cord-260087-9o9tb28h 16 14 highconsequence highconsequence NN cord-260087-9o9tb28h 16 15 pathogens pathogen NNS cord-260087-9o9tb28h 16 16 causing cause VBG cord-260087-9o9tb28h 16 17 community community NN cord-260087-9o9tb28h 16 18 infections infection NNS cord-260087-9o9tb28h 16 19 typically typically RB cord-260087-9o9tb28h 16 20 occur occur VBP cord-260087-9o9tb28h 16 21 from from IN cord-260087-9o9tb28h 16 22 state state NN cord-260087-9o9tb28h 16 23 - - HYPH cord-260087-9o9tb28h 16 24 of of IN cord-260087-9o9tb28h 16 25 - - HYPH cord-260087-9o9tb28h 16 26 the the DT cord-260087-9o9tb28h 16 27 - - HYPH cord-260087-9o9tb28h 16 28 art art NN cord-260087-9o9tb28h 16 29 laboratories laboratory NNS cord-260087-9o9tb28h 16 30 , , , cord-260087-9o9tb28h 16 31 including include VBG cord-260087-9o9tb28h 16 32 six six CD cord-260087-9o9tb28h 16 33 outbreaks outbreak NNS cord-260087-9o9tb28h 16 34 of of IN cord-260087-9o9tb28h 16 35 severe severe JJ cord-260087-9o9tb28h 16 36 acute acute JJ cord-260087-9o9tb28h 16 37 respiratory respiratory JJ cord-260087-9o9tb28h 16 38 syndrome syndrome NN cord-260087-9o9tb28h 16 39 and and CC cord-260087-9o9tb28h 16 40 one one CD cord-260087-9o9tb28h 16 41 of of IN cord-260087-9o9tb28h 16 42 foot foot NN cord-260087-9o9tb28h 16 43 - - HYPH cord-260087-9o9tb28h 16 44 and and CC cord-260087-9o9tb28h 16 45 - - HYPH cord-260087-9o9tb28h 16 46 mouth mouth NN cord-260087-9o9tb28h 16 47 disease disease NN cord-260087-9o9tb28h 16 48 since since IN cord-260087-9o9tb28h 16 49 2003 2003 CD cord-260087-9o9tb28h 16 50 . . . cord-260087-9o9tb28h 17 1 Since since IN cord-260087-9o9tb28h 17 2 2014 2014 CD cord-260087-9o9tb28h 17 3 , , , cord-260087-9o9tb28h 17 4 four four CD cord-260087-9o9tb28h 17 5 extramural extramural JJ cord-260087-9o9tb28h 17 6 escapes escape NNS cord-260087-9o9tb28h 17 7 of of IN cord-260087-9o9tb28h 17 8 high high JJ cord-260087-9o9tb28h 17 9 - - HYPH cord-260087-9o9tb28h 17 10 consequence consequence NN cord-260087-9o9tb28h 17 11 pathogens pathogen NNS cord-260087-9o9tb28h 17 12 have have VBP cord-260087-9o9tb28h 17 13 originated originate VBN cord-260087-9o9tb28h 17 14 from from IN cord-260087-9o9tb28h 17 15 prestigious prestigious JJ cord-260087-9o9tb28h 17 16 U.S. U.S. NNP cord-260087-9o9tb28h 17 17 laboratories laboratory NNS cord-260087-9o9tb28h 17 18 . . . cord-260087-9o9tb28h 18 1 Vir Vir NNP cord-260087-9o9tb28h 18 2 - - HYPH cord-260087-9o9tb28h 18 3 ulent ulent JJ cord-260087-9o9tb28h 18 4 anthrax anthrax NN cord-260087-9o9tb28h 18 5 and and CC cord-260087-9o9tb28h 18 6 avian avian JJ cord-260087-9o9tb28h 18 7 influenza influenza NN cord-260087-9o9tb28h 18 8 virus virus NN cord-260087-9o9tb28h 18 9 sent send VBN cord-260087-9o9tb28h 18 10 from from IN cord-260087-9o9tb28h 18 11 the the DT cord-260087-9o9tb28h 18 12 CDC CDC NNP cord-260087-9o9tb28h 18 13 ( ( -LRB- cord-260087-9o9tb28h 18 14 3 3 CD cord-260087-9o9tb28h 18 15 ) ) -RRB- cord-260087-9o9tb28h 18 16 and and CC cord-260087-9o9tb28h 18 17 anthrax anthrax NN cord-260087-9o9tb28h 18 18 sent send VBN cord-260087-9o9tb28h 18 19 from from IN cord-260087-9o9tb28h 18 20 Dugway Dugway NNP cord-260087-9o9tb28h 18 21 Proving Proving NNP cord-260087-9o9tb28h 18 22 Ground Ground NNP cord-260087-9o9tb28h 18 23 ( ( -LRB- cord-260087-9o9tb28h 18 24 4 4 CD cord-260087-9o9tb28h 18 25 ) ) -RRB- cord-260087-9o9tb28h 18 26 by by IN cord-260087-9o9tb28h 18 27 public public JJ cord-260087-9o9tb28h 18 28 carriers carrier NNS cord-260087-9o9tb28h 18 29 entered enter VBD cord-260087-9o9tb28h 18 30 nonsecure nonsecure NN cord-260087-9o9tb28h 18 31 areas area NNS cord-260087-9o9tb28h 18 32 of of IN cord-260087-9o9tb28h 18 33 other other JJ cord-260087-9o9tb28h 18 34 laboratories laboratory NNS cord-260087-9o9tb28h 18 35 . . . cord-260087-9o9tb28h 19 1 Activities activity NNS cord-260087-9o9tb28h 19 2 at at IN cord-260087-9o9tb28h 19 3 the the DT cord-260087-9o9tb28h 19 4 select select JJ cord-260087-9o9tb28h 19 5 agent agent NN cord-260087-9o9tb28h 19 6 laboratory laboratory NN cord-260087-9o9tb28h 19 7 at at IN cord-260087-9o9tb28h 19 8 the the DT cord-260087-9o9tb28h 19 9 Tulane Tulane NNP cord-260087-9o9tb28h 19 10 National National NNP cord-260087-9o9tb28h 19 11 Primate Primate NNP cord-260087-9o9tb28h 19 12 Research Research NNP cord-260087-9o9tb28h 19 13 Center Center NNP cord-260087-9o9tb28h 19 14 remain remain VBP cord-260087-9o9tb28h 19 15 suspended suspend VBN cord-260087-9o9tb28h 19 16 after after IN cord-260087-9o9tb28h 19 17 Burkholderia Burkholderia NNP cord-260087-9o9tb28h 19 18 pseudomallei pseudomallei NN cord-260087-9o9tb28h 19 19 , , , cord-260087-9o9tb28h 19 20 the the DT cord-260087-9o9tb28h 19 21 agent agent NN cord-260087-9o9tb28h 19 22 of of IN cord-260087-9o9tb28h 19 23 melioidosis melioidosis NNP cord-260087-9o9tb28h 19 24 , , , cord-260087-9o9tb28h 19 25 escaped escape VBD cord-260087-9o9tb28h 19 26 containment containment NN cord-260087-9o9tb28h 19 27 and and CC cord-260087-9o9tb28h 19 28 caused cause VBD cord-260087-9o9tb28h 19 29 multiple multiple JJ cord-260087-9o9tb28h 19 30 primate primate JJ cord-260087-9o9tb28h 19 31 infections infection NNS cord-260087-9o9tb28h 19 32 in in IN cord-260087-9o9tb28h 19 33 an an DT cord-260087-9o9tb28h 19 34 outdoor outdoor JJ cord-260087-9o9tb28h 19 35 primate primate NN cord-260087-9o9tb28h 19 36 facility facility NN cord-260087-9o9tb28h 19 37 ( ( -LRB- cord-260087-9o9tb28h 19 38 5 5 CD cord-260087-9o9tb28h 19 39 , , , cord-260087-9o9tb28h 19 40 6 6 CD cord-260087-9o9tb28h 19 41 ) ) -RRB- cord-260087-9o9tb28h 19 42 . . . cord-260087-9o9tb28h 20 1 The the DT cord-260087-9o9tb28h 20 2 incidence incidence NN cord-260087-9o9tb28h 20 3 of of IN cord-260087-9o9tb28h 20 4 laboratory laboratory NN cord-260087-9o9tb28h 20 5 accidents accident NNS cord-260087-9o9tb28h 20 6 that that WDT cord-260087-9o9tb28h 20 7 offer offer VBP cord-260087-9o9tb28h 20 8 an an DT cord-260087-9o9tb28h 20 9 exit exit NN cord-260087-9o9tb28h 20 10 path path NN cord-260087-9o9tb28h 20 11 for for IN cord-260087-9o9tb28h 20 12 high high JJ cord-260087-9o9tb28h 20 13 - - HYPH cord-260087-9o9tb28h 20 14 consequence consequence NN cord-260087-9o9tb28h 20 15 pathogens pathogen NNS cord-260087-9o9tb28h 20 16 into into IN cord-260087-9o9tb28h 20 17 the the DT cord-260087-9o9tb28h 20 18 community community NN cord-260087-9o9tb28h 20 19 through through IN cord-260087-9o9tb28h 20 20 worker worker NN cord-260087-9o9tb28h 20 21 infection infection NN cord-260087-9o9tb28h 20 22 is be VBZ cord-260087-9o9tb28h 20 23 unsettlingly unsettlingly RB cord-260087-9o9tb28h 20 24 high high JJ cord-260087-9o9tb28h 20 25 . . . cord-260087-9o9tb28h 21 1 In in IN cord-260087-9o9tb28h 21 2 2010 2010 CD cord-260087-9o9tb28h 21 3 , , , cord-260087-9o9tb28h 21 4 the the DT cord-260087-9o9tb28h 21 5 most most RBS cord-260087-9o9tb28h 21 6 recent recent JJ cord-260087-9o9tb28h 21 7 year year NN cord-260087-9o9tb28h 21 8 for for IN cord-260087-9o9tb28h 21 9 which which WDT cord-260087-9o9tb28h 21 10 data datum NNS cord-260087-9o9tb28h 21 11 have have VBP cord-260087-9o9tb28h 21 12 been be VBN cord-260087-9o9tb28h 21 13 reported report VBN cord-260087-9o9tb28h 21 14 ( ( -LRB- cord-260087-9o9tb28h 21 15 7 7 CD cord-260087-9o9tb28h 21 16 ) ) -RRB- cord-260087-9o9tb28h 21 17 , , , cord-260087-9o9tb28h 21 18 the the DT cord-260087-9o9tb28h 21 19 CDC CDC NNP cord-260087-9o9tb28h 21 20 received receive VBD cord-260087-9o9tb28h 21 21 96 96 CD cord-260087-9o9tb28h 21 22 reports report NNS cord-260087-9o9tb28h 21 23 of of IN cord-260087-9o9tb28h 21 24 releases release NNS cord-260087-9o9tb28h 21 25 ( ( -LRB- cord-260087-9o9tb28h 21 26 intramural intramural JJ cord-260087-9o9tb28h 21 27 breaches breach NNS cord-260087-9o9tb28h 21 28 of of IN cord-260087-9o9tb28h 21 29 containment containment NN cord-260087-9o9tb28h 21 30 ) ) -RRB- cord-260087-9o9tb28h 21 31 of of IN cord-260087-9o9tb28h 21 32 select select JJ cord-260087-9o9tb28h 21 33 agents agent NNS cord-260087-9o9tb28h 21 34 from from IN cord-260087-9o9tb28h 21 35 state state NN cord-260087-9o9tb28h 21 36 - - HYPH cord-260087-9o9tb28h 21 37 of of IN cord-260087-9o9tb28h 21 38 - - HYPH cord-260087-9o9tb28h 21 39 the the DT cord-260087-9o9tb28h 21 40 - - HYPH cord-260087-9o9tb28h 21 41 art art NN cord-260087-9o9tb28h 21 42 select select JJ cord-260087-9o9tb28h 21 43 agent agent NN cord-260087-9o9tb28h 21 44 - - HYPH cord-260087-9o9tb28h 21 45 approved approve VBN cord-260087-9o9tb28h 21 46 laboratories laboratory NNS cord-260087-9o9tb28h 21 47 . . . cord-260087-9o9tb28h 22 1 In in IN cord-260087-9o9tb28h 22 2 these these DT cord-260087-9o9tb28h 22 3 elite elite JJ cord-260087-9o9tb28h 22 4 laboratories laboratory NNS cord-260087-9o9tb28h 22 5 , , , cord-260087-9o9tb28h 22 6 a a DT cord-260087-9o9tb28h 22 7 breach breach NN cord-260087-9o9tb28h 22 8 of of IN cord-260087-9o9tb28h 22 9 containment containment NN cord-260087-9o9tb28h 22 10 happens happen VBZ cord-260087-9o9tb28h 22 11 about about IN cord-260087-9o9tb28h 22 12 twice twice RB cord-260087-9o9tb28h 22 13 weekly weekly JJ cord-260087-9o9tb28h 22 14 . . . cord-260087-9o9tb28h 23 1 The the DT cord-260087-9o9tb28h 23 2 reemergent reemergent NN cord-260087-9o9tb28h 23 3 1977 1977 CD cord-260087-9o9tb28h 23 4 H1N1 H1N1 NNP cord-260087-9o9tb28h 23 5 strain strain NN cord-260087-9o9tb28h 23 6 and and CC cord-260087-9o9tb28h 23 7 the the DT cord-260087-9o9tb28h 23 8 gain gain NN cord-260087-9o9tb28h 23 9 - - HYPH cord-260087-9o9tb28h 23 10 of of IN cord-260087-9o9tb28h 23 11 - - HYPH cord-260087-9o9tb28h 23 12 function function NN cord-260087-9o9tb28h 23 13 debate debate NN cord-260087-9o9tb28h 23 14 Threatened threaten VBN cord-260087-9o9tb28h 23 15 pandemics pandemic NNS cord-260087-9o9tb28h 23 16 and and CC cord-260087-9o9tb28h 23 17 laboratory laboratory NN cord-260087-9o9tb28h 23 18 escapes escape VBZ cord-260087-9o9tb28h 23 19 : : : cord-260087-9o9tb28h 24 1 selffulfilling selffulfilling NNP cord-260087-9o9tb28h 24 2 prophecies prophecies NNPS cord-260087-9o9tb28h 24 3 C.D.C. C.D.C. NNP cord-260087-9o9tb28h 24 4 closes close VBZ cord-260087-9o9tb28h 24 5 anthrax anthrax NN cord-260087-9o9tb28h 24 6 and and CC cord-260087-9o9tb28h 24 7 flu flu NN cord-260087-9o9tb28h 24 8 labs lab NNS cord-260087-9o9tb28h 24 9 after after IN cord-260087-9o9tb28h 24 10 accidents accident NNS cord-260087-9o9tb28h 24 11 Review Review NNP cord-260087-9o9tb28h 24 12 Committee Committee NNP cord-260087-9o9tb28h 24 13 report report NN cord-260087-9o9tb28h 24 14 : : : cord-260087-9o9tb28h 25 1 inadvertent inadvertent JJ cord-260087-9o9tb28h 25 2 shipment shipment NN cord-260087-9o9tb28h 25 3 of of IN cord-260087-9o9tb28h 25 4 live live JJ cord-260087-9o9tb28h 25 5 Bacillus bacillus NN cord-260087-9o9tb28h 25 6 anthracis anthracis NN cord-260087-9o9tb28h 25 7 spores spore NNS cord-260087-9o9tb28h 25 8 by by IN cord-260087-9o9tb28h 25 9 DoD DoD NNP cord-260087-9o9tb28h 25 10 Escape Escape NNP cord-260087-9o9tb28h 25 11 of of IN cord-260087-9o9tb28h 25 12 dangerous dangerous JJ cord-260087-9o9tb28h 25 13 bacterium bacterium NN cord-260087-9o9tb28h 25 14 leads lead VBZ cord-260087-9o9tb28h 25 15 to to TO cord-260087-9o9tb28h 25 16 halt halt VB cord-260087-9o9tb28h 25 17 of of IN cord-260087-9o9tb28h 25 18 risky risky JJ cord-260087-9o9tb28h 25 19 studies study NNS cord-260087-9o9tb28h 25 20 at at IN cord-260087-9o9tb28h 25 21 News News NNP cord-260087-9o9tb28h 25 22 release release NN cord-260087-9o9tb28h 25 23 . . . cord-260087-9o9tb28h 26 1 Conclusion conclusion NN cord-260087-9o9tb28h 26 2 of of IN cord-260087-9o9tb28h 26 3 select select JJ cord-260087-9o9tb28h 26 4 agent agent NN cord-260087-9o9tb28h 26 5 inquiry inquiry NN cord-260087-9o9tb28h 26 6 into into IN cord-260087-9o9tb28h 26 7 Burkholderia Burkholderia NNP cord-260087-9o9tb28h 26 8 pseudomallei pseudomallei NN cord-260087-9o9tb28h 26 9 release release NN cord-260087-9o9tb28h 26 10 at at IN cord-260087-9o9tb28h 26 11 Tulane Tulane NNP cord-260087-9o9tb28h 26 12 National National NNP cord-260087-9o9tb28h 26 13 Primate Primate NNP cord-260087-9o9tb28h 26 14 Research Research NNP cord-260087-9o9tb28h 26 15 Center Center NNP cord-260087-9o9tb28h 26 16 Monitoring Monitoring NNP cord-260087-9o9tb28h 26 17 select select JJ cord-260087-9o9tb28h 26 18 agent agent NN cord-260087-9o9tb28h 26 19 theft theft NN cord-260087-9o9tb28h 26 20 , , , cord-260087-9o9tb28h 26 21 loss loss NN cord-260087-9o9tb28h 26 22 and and CC cord-260087-9o9tb28h 26 23 release release NN cord-260087-9o9tb28h 26 24 reports report NNS cord-260087-9o9tb28h 26 25 in in IN cord-260087-9o9tb28h 26 26 the the DT cord-260087-9o9tb28h 26 27 United United NNP cord-260087-9o9tb28h 26 28 States-2004 States-2004 NNP cord-260087-9o9tb28h 26 29 -2010 -2010 .