id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-290297-efo9f7c5	Vaillancourt, Mylene	The Unrecognized Threat of Secondary Bacterial Infections with COVID-19	2020-08-07		.txt	text/plain	1354	72	37	In recent studies on COVID-19 patients, secondary bacterial infections were significantly associated with worse outcomes and death despite antimicrobial therapies. In the past, the intensive use of antibiotics during the severe acute respiratory syndrome coronavirus (SARS-CoV) pandemic led to increases in the prevalence of multidrug-resistant bacteria. T he outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), is the greatest pandemic of our generation, with 16 million people infected and 650,000 deaths worldwide so far (1) . In a multicenter study that included 476 COVID-19 patients, secondary bacterial infections were significantly associated with outcome severity (2) . During the first SARS-CoV outbreak in 2003, up to 30% of patients were diagnosed with secondary bacterial infections and coinfection was positively associated with disease severity (5, 6) . Increase in methicillin-resistant Staphylococcus aureus acquisition rate and change in pathogen pattern associated with an outbreak of severe acute respiratory syndrome	./cache/cord-290297-efo9f7c5.txt	./txt/cord-290297-efo9f7c5.txt