id author title date pages extension mime words sentences flesch summary cache txt cord-328548-5kjq9xqs Oliveira J. e Silva, Lucas Flexibilization of Science, Cognitive Biases, and the COVID-19 Pandemic 2020-08-27 .txt text/plain 1463 78 46 A subsequent high-profile paper associating the use of hydroxychloroquine with increased mortality in the treatment of COVID-19 had to be retracted 2 after scientists pointed out issues such as mismatched mortality rates when compared to Australian official reports, no release of the dataset for independent analysis, and lack of thorough ethical review. The term "flexibilization" here refers to a loosening of methodological standards and the development of low-quality studies, leading to the creation of unreliable data and, later in the cycle, of anecdotal evidence. Within this context, science and clinical research have been creating rigorous methodological standards in order to produce high-quality studies that allow us to have greater confidence in the evidence while mitigating unnecessary damage. During the COVID-19 pandemic, the early adoption of new interventions by clinicians and policy makers based on promising but often low-quality data is creating a scenario from which anecdotal evidence may emerge. ./cache/cord-328548-5kjq9xqs.txt ./txt/cord-328548-5kjq9xqs.txt