id author title date pages extension mime words sentences flesch summary cache txt cord-322714-s0wge7o4 Joyner, Michael J. Safety Update: COVID-19 Convalescent Plasma in 20,000 Hospitalized Patients 2020-07-19 .txt text/plain 3291 178 48 Recently, our investigation of key safety indicators in 5,000 patients transfused with COVID-19 convalescent plasma demonstrated an incidence of transfusion-related serious adverse events (SAE) of less than 1% and a mortality rate of 14.9% 10 . Web-based, standardized data reporting surveys were completed to assess clinical status of patients at regular time intervals (four-hours and seven-days after convalescent plasma transfusion) using the Research Electronic Data Capture system (REDCap, v.9.1.15 Vanderbilt University, Nashville, TN) 14, 15 . In this safety update of the US Convalescent Plasma Expanded Access Program of 20,000 hospitalized patients in the US with severe or life-threatening COVID-19, the overall frequency of SAEs classified as attributable or likely secondary to convalescent plasma transfusion continued to be low (<1% of all transfusions) and the seven-day mortality rate in this extremely high risk cohort was 8.6%. ./cache/cord-322714-s0wge7o4.txt ./txt/cord-322714-s0wge7o4.txt