id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-292606-tqjmg3qb	Testori, Alessandro	THE “PERFECT CYTOKINE STORM” OF COVID-19	2020-05-29		.txt	text/plain	903	56	51	The vast majority of the deaths caused by severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) are patients over the age of 55, which died of Acute Respiratory Distress Syndrome (ARDS). IL -10 is another anti-inflammatory molecule that could be tested and it could be administered via a genetherapy approach using naked plasmid DNA vectors 4 engineered to produce IL-10 inside the recipient cells, thus reducing the cost and simplifying production. Countries need to invest in technologies like DNA vaccines 5 and antiviral gene therapy strategies, like RNAi technology, which is an ideal tool for inhibiting viral replication in host cells as the siRNA can interact with certain viral genes and silence their expression. We need to develop detailed protocols now on how to quickly produce vaccines and antivirals, that can be adapted to future viral pandemics.	./cache/cord-292606-tqjmg3qb.txt	./txt/cord-292606-tqjmg3qb.txt