id author title date pages extension mime words sentences flesch summary cache txt cord-292398-3b2e8x8z Siuka, Darko Vitamin D supplementation in the COVID-19 pandemic 2020-06-06 .txt text/plain 599 38 42 Considering the studies on the role of vitamin D in the prevention of acute respiratory infections, supplementation of vitamin D may be reasonable also for the prevention of SARS-CoV-2 infections and reducing morbidity and mortality in COVID-19 high-risk patients. Studies of vitamin D replacement have demonstrated that vitamin D ameliorates innate immunity (the immediate response of macrophages to invading viruses and bacteria in the mucous membranes), 2 thereby reducing the incidence and severity of acute respiratory infections. Therefore, we suggest it would be reasonable to supplement vitamin D in subpopulations at risk of vitamin D deficiency and unfavorable COVID-19 outcomes, as well as in individuals already infected with SARS-CoV-2 to achieve optimal 25(OH)D3 concentrations as quickly as possible. Decisions should therefore always be evidence informed, but they will very rarely be purely evidence based." 5 In Slovenia, in the view of COVID-19 pandemic, medical doctors were urgently advised by leading experts to supplement vitamin D in high-risk and fragile individuals and in COVID-19 patients. ./cache/cord-292398-3b2e8x8z.txt ./txt/cord-292398-3b2e8x8z.txt