id author title date pages extension mime words sentences flesch summary cache txt cord-277342-40d24mvm Chen, Yu SARS-CoV-2: virus dynamics and host response 2020-03-23 .txt text/plain 804 57 53 In The Lancet Infectious Diseases, Kelvin To and colleagues 4 report the viral load and antibody profiles of a cohort of 23 patients admitted to hospital with COVID-19. First, the high viral load during the early phase of illness suggests that patients could be most infectious during this period, and it might account for the high transmissibility of SARS-CoV-2. Second, age was associated with viral load in this study, which could explain the high degree of severe disease in older patients with SARS-CoV-2. 5, 6 The high viral load in elderly patients is associated not only with low immunity but also with high expression of the ACE2 receptor (the cellentry receptor for SARS-CoV-2) in older adults. Clinical findings in a group of patients infected with the 2019 novel coronavirus (SARS-Cov-2) outside of Wuhan, China: retrospective case series Epidemiologic features and clinical course of patients infected with SARS-CoV-2 in Singapore ./cache/cord-277342-40d24mvm.txt ./txt/cord-277342-40d24mvm.txt