id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-261133-m00gcci4	Eccles, Ron	Understanding the symptoms of the common cold and influenza	2005-10-25		.txt	text/plain	5302	280	48	52 The mechanism of headache caused by cytokines is unknown but it is interesting that headache induced by cytokines is accompanied by symptoms such as fatigue, anorexia, malaise, nausea, and depression, and these symptoms are commonly associated with URTIs. A sensation of chilliness is an early symptom of common cold, 7 and is sometimes explained as an initial stage of fever, since vasoconstriction of skin blood vessels may cause a fall in skin temperature that is perceived as chilliness. 65 The cytokine stimulation of prostaglandin E2 production in skeletal muscle, and the effects of prostaglandin E2 on sensory nerves in muscle, may explain the myalgia associated with URTIs. In a study of common cold symptoms induced by challenge with infected nasal secretions, URTI symptoms were classified as either "early" or "later" symptoms.	./cache/cord-261133-m00gcci4.txt	./txt/cord-261133-m00gcci4.txt