id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-313845-757yiqlg	Kirschenbaum, Daniel	Inflammatory olfactory neuropathy in two patients with COVID-19	2020-07-10		.txt	text/plain	568	45	47	title: Inflammatory olfactory neuropathy in two patients with COVID-19 We report two cases of olfactory neuropathy diagnosed at autopsy in patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Postmortem histological analysis of the olfactory epithelium in both patients showed prominent leukocytic infiltrates in the lamina propria and focal atrophy of the mucosa. In both patients, the olfactory tracts showed few isolated CD45-positive infiltrates; the olfactory striae were unremarkable. 1 Inflammation of the olfactory system and anosmia have been reported in other viral diseases, 2 as was age-related atrophy of the olfactory epithelium. 4 Consistent with previous reports, the olfactory tracts were largely unremarkable, except for a few endoneurial leukocytes in both patients. 5 SARS-CoV-2induced damage might be medi ated by viral entry through its receptor angiotensin converting enzyme 2 and the transmembrane serine protease 2, which are ex pressed in non-neural cells of the olfactory epithelium. Anosmia and dysgeusia in patients with mild SARS-CoV-2 infection	./cache/cord-313845-757yiqlg.txt	./txt/cord-313845-757yiqlg.txt