id author title date pages extension mime words sentences flesch summary cache txt cord-313028-0nhgxoim Huang, Chaolin Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China 2020-01-24 .txt text/plain 4784 248 49 INTERPRETATION: The 2019-nCoV infection caused clusters of severe respiratory illness similar to severe acute respiratory syndrome coronavirus and was associated with ICU admission and high mortality. Following the pneumonia cases of unknown cause reported in Wuhan and considering the shared history of exposure to Huanan seafood market across the patients, an epidemiological alert was released by the local health authority on Dec 31, 2019, and the market was shut down on Jan 1, 2020. 16 Secondary infection was diagnosed if the patients had clinical symptoms or signs of nosocomial pneumonia or bacteraemia, and was combined with a positive culture of a new pathogen from a lower respiratory tract specimen (including the sputum, transtracheal aspirates, or bronchoalveolar lavage fluid, or from blood samples taken ≥48 h after admission). In view of the high amount of cytokines induced by SARS-CoV, 22, 24 MERS-CoV, 25, 26 and 2019-nCoV infections, corticosteroids were used frequently for treatment of patients with severe illness, for possible benefit by reducing inflammatory-induced lung injury. ./cache/cord-313028-0nhgxoim.txt ./txt/cord-313028-0nhgxoim.txt