id author title date pages extension mime words sentences flesch summary cache txt cord-312167-d16ylykc Lazzarin, Serena Marita Successful treatment of HIV-associated tumefactive demyelinating lesions with corticosteroids and cyclophosphamide: a case report 2020-11-03 .txt text/plain 834 60 42 title: Successful treatment of HIV-associated tumefactive demyelinating lesions with corticosteroids and cyclophosphamide: a case report Two days after the last dose, a follow-up brain MRI showed dimensional decrease of both frontal lesions, with disappearance of mass effect; gadolinium enhancement was substantially decreased (Fig. 1 ). A clinical and neuroradiological 6-month follow-up has been scheduled to assess the stability of patient's condition; [4] , but we cannot even exclude a direct role for HIV in the demyelinating process. Based on our experience, a treatment with cyclophosphamide may be a valid alternative in steroid-resistant HIV patients with TDLs. Author contributions SML contributed to paper conception, data collection, analysis and interpretation, literature review and paper drafting. Fig. 1 (1) Serial 1.5-T MRI axial brain scans, performed after admission (a), at one (b) and 3 months (c) after the clinical onset of a frontal lobe syndrome due to large tumefactive demyelinating lesions. ./cache/cord-312167-d16ylykc.txt ./txt/cord-312167-d16ylykc.txt