id sid tid token lemma pos cord-288072-42sx52tn 1 1 key key JJ cord-288072-42sx52tn 1 2 : : : cord-288072-42sx52tn 1 3 cord-288072 cord-288072 NNP cord-288072-42sx52tn 1 4 - - HYPH cord-288072-42sx52tn 1 5 42sx52tn 42sx52tn CD cord-288072-42sx52tn 1 6 authors author NNS cord-288072-42sx52tn 1 7 : : : cord-288072-42sx52tn 1 8 Monto Monto NNP cord-288072-42sx52tn 1 9 , , , cord-288072-42sx52tn 1 10 Arnold Arnold NNP cord-288072-42sx52tn 1 11 S. S. NNP cord-288072-42sx52tn 1 12 ; ; : cord-288072-42sx52tn 1 13 Lim Lim NNP cord-288072-42sx52tn 1 14 , , , cord-288072-42sx52tn 2 1 Sook Sook NNP cord-288072-42sx52tn 2 2 K. K. NNP cord-288072-42sx52tn 2 3 title title NN cord-288072-42sx52tn 2 4 : : : cord-288072-42sx52tn 2 5 The the DT cord-288072-42sx52tn 2 6 Tecumseh Tecumseh NNP cord-288072-42sx52tn 2 7 Study Study NNP cord-288072-42sx52tn 2 8 of of IN cord-288072-42sx52tn 2 9 Respiratory Respiratory NNP cord-288072-42sx52tn 2 10 Illness Illness NNP cord-288072-42sx52tn 2 11 . . . cord-288072-42sx52tn 3 1 VI VI NNP cord-288072-42sx52tn 3 2 . . . cord-288072-42sx52tn 4 1 Frequency frequency NN cord-288072-42sx52tn 4 2 of of IN cord-288072-42sx52tn 4 3 and and CC cord-288072-42sx52tn 4 4 Relationship relationship NN cord-288072-42sx52tn 4 5 between between IN cord-288072-42sx52tn 4 6 Outbreaks outbreak NNS cord-288072-42sx52tn 4 7 of of IN cord-288072-42sx52tn 4 8 Coronavims Coronavims NNP cord-288072-42sx52tn 4 9 Infection Infection NNP cord-288072-42sx52tn 4 10 date date NN cord-288072-42sx52tn 4 11 : : : cord-288072-42sx52tn 4 12 1974 1974 CD cord-288072-42sx52tn 4 13 - - SYM cord-288072-42sx52tn 4 14 03 03 CD cord-288072-42sx52tn 4 15 - - SYM cord-288072-42sx52tn 4 16 17 17 CD cord-288072-42sx52tn 4 17 journal journal NN cord-288072-42sx52tn 4 18 : : : cord-288072-42sx52tn 5 1 J J NNP cord-288072-42sx52tn 5 2 Infect infect VBP cord-288072-42sx52tn 5 3 Dis Dis NNP cord-288072-42sx52tn 5 4 DOI doi NN cord-288072-42sx52tn 5 5 : : : cord-288072-42sx52tn 5 6 10.1093 10.1093 CD cord-288072-42sx52tn 5 7 / / SYM cord-288072-42sx52tn 5 8 infdis/129.3.271 infdis/129.3.271 NNP cord-288072-42sx52tn 5 9 sha sha NNP cord-288072-42sx52tn 5 10 : : : cord-288072-42sx52tn 5 11 b95dfcfa5209e75d096f33a43969ecff9ef0b700 b95dfcfa5209e75d096f33a43969ecff9ef0b700 NNP cord-288072-42sx52tn 5 12 doc_id doc_id CD cord-288072-42sx52tn 5 13 : : : cord-288072-42sx52tn 5 14 288072 288072 CD cord-288072-42sx52tn 5 15 cord_uid cord_uid NN cord-288072-42sx52tn 5 16 : : : cord-288072-42sx52tn 6 1 42sx52tn 42sx52tn CD cord-288072-42sx52tn 6 2 Specimens specimen NNS cord-288072-42sx52tn 6 3 of of IN cord-288072-42sx52tn 6 4 blood blood NN cord-288072-42sx52tn 6 5 collected collect VBN cord-288072-42sx52tn 6 6 in in IN cord-288072-42sx52tn 6 7 Tecumseh Tecumseh NNP cord-288072-42sx52tn 6 8 , , , cord-288072-42sx52tn 6 9 Michigan Michigan NNP cord-288072-42sx52tn 6 10 over over IN cord-288072-42sx52tn 6 11 a a DT cord-288072-42sx52tn 6 12 four four CD cord-288072-42sx52tn 6 13 - - HYPH cord-288072-42sx52tn 6 14 year year NN cord-288072-42sx52tn 6 15 period period NN cord-288072-42sx52tn 6 16 were be VBD cord-288072-42sx52tn 6 17 studied study VBN cord-288072-42sx52tn 6 18 for for IN cord-288072-42sx52tn 6 19 rise rise NN cord-288072-42sx52tn 6 20 in in IN cord-288072-42sx52tn 6 21 antibody antibody NN cord-288072-42sx52tn 6 22 titer titer NN cord-288072-42sx52tn 6 23 against against IN cord-288072-42sx52tn 6 24 coronavirus coronavirus NN cord-288072-42sx52tn 6 25 OC43 OC43 NNP cord-288072-42sx52tn 6 26 . . . cord-288072-42sx52tn 7 1 Peaks peak NNS cord-288072-42sx52tn 7 2 of of IN cord-288072-42sx52tn 7 3 infection infection NN cord-288072-42sx52tn 7 4 were be VBD cord-288072-42sx52tn 7 5 found find VBN cord-288072-42sx52tn 7 6 in in IN cord-288072-42sx52tn 7 7 the the DT cord-288072-42sx52tn 7 8 winter winter NN cord-288072-42sx52tn 7 9 and and CC cord-288072-42sx52tn 7 10 spring spring NN cord-288072-42sx52tn 7 11 of of IN cord-288072-42sx52tn 7 12 1966 1966 CD cord-288072-42sx52tn 7 13 , , , cord-288072-42sx52tn 7 14 1968 1968 CD cord-288072-42sx52tn 7 15 , , , cord-288072-42sx52tn 7 16 and and CC cord-288072-42sx52tn 7 17 1969 1969 CD cord-288072-42sx52tn 7 18 ; ; : cord-288072-42sx52tn 7 19 at at IN cord-288072-42sx52tn 7 20 other other JJ cord-288072-42sx52tn 7 21 times time NNS cord-288072-42sx52tn 7 22 , , , cord-288072-42sx52tn 7 23 infections infection NNS cord-288072-42sx52tn 7 24 occurred occur VBD cord-288072-42sx52tn 7 25 sporadically sporadically RB cord-288072-42sx52tn 7 26 . . . cord-288072-42sx52tn 8 1 All all DT cord-288072-42sx52tn 8 2 age age NN cord-288072-42sx52tn 8 3 groups group NNS cord-288072-42sx52tn 8 4 were be VBD cord-288072-42sx52tn 8 5 involved involve VBN cord-288072-42sx52tn 8 6 , , , cord-288072-42sx52tn 8 7 especially especially RB cord-288072-42sx52tn 8 8 the the DT cord-288072-42sx52tn 8 9 very very RB cord-288072-42sx52tn 8 10 young young JJ cord-288072-42sx52tn 8 11 . . . cord-288072-42sx52tn 9 1 Rises rise NNS cord-288072-42sx52tn 9 2 in in IN cord-288072-42sx52tn 9 3 titer titer NN cord-288072-42sx52tn 9 4 by by IN cord-288072-42sx52tn 9 5 CF CF NNP cord-288072-42sx52tn 9 6 and and CC cord-288072-42sx52tn 9 7 by by IN cord-288072-42sx52tn 9 8 HAI HAI NNP cord-288072-42sx52tn 9 9 tests test NNS cord-288072-42sx52tn 9 10 frequently frequently RB cord-288072-42sx52tn 9 11 did do VBD cord-288072-42sx52tn 9 12 not not RB cord-288072-42sx52tn 9 13 occur occur VB cord-288072-42sx52tn 9 14 together together RB cord-288072-42sx52tn 9 15 in in IN cord-288072-42sx52tn 9 16 the the DT cord-288072-42sx52tn 9 17 same same JJ cord-288072-42sx52tn 9 18 individual individual NN cord-288072-42sx52tn 9 19 . . . cord-288072-42sx52tn 10 1 Agreement agreement NN cord-288072-42sx52tn 10 2 between between IN cord-288072-42sx52tn 10 3 the the DT cord-288072-42sx52tn 10 4 two two CD cord-288072-42sx52tn 10 5 tests test NNS cord-288072-42sx52tn 10 6 was be VBD cord-288072-42sx52tn 10 7 better well JJR cord-288072-42sx52tn 10 8 in in IN cord-288072-42sx52tn 10 9 1966 1966 CD cord-288072-42sx52tn 10 10 and and CC cord-288072-42sx52tn 10 11 1969 1969 CD cord-288072-42sx52tn 10 12 than than IN cord-288072-42sx52tn 10 13 in in IN cord-288072-42sx52tn 10 14 the the DT cord-288072-42sx52tn 10 15 other other JJ cord-288072-42sx52tn 10 16 years year NNS cord-288072-42sx52tn 10 17 . . . cord-288072-42sx52tn 11 1 A a DT cord-288072-42sx52tn 11 2 portion portion NN cord-288072-42sx52tn 11 3 of of IN cord-288072-42sx52tn 11 4 the the DT cord-288072-42sx52tn 11 5 paired pair VBN cord-288072-42sx52tn 11 6 specimens specimen NNS cord-288072-42sx52tn 11 7 showing show VBG cord-288072-42sx52tn 11 8 rises rise NNS cord-288072-42sx52tn 11 9 in in IN cord-288072-42sx52tn 11 10 CF cf NN cord-288072-42sx52tn 12 1 and/ and/ NNP cord-288072-42sx52tn 12 2 or or CC cord-288072-42sx52tn 12 3 HAI HAI NNP cord-288072-42sx52tn 12 4 titer titer NN cord-288072-42sx52tn 12 5 was be VBD cord-288072-42sx52tn 12 6 tested test VBN cord-288072-42sx52tn 12 7 by by IN cord-288072-42sx52tn 12 8 neutralization neutralization NN cord-288072-42sx52tn 12 9 . . . cord-288072-42sx52tn 13 1 Rises rise NNS cord-288072-42sx52tn 13 2 in in IN cord-288072-42sx52tn 13 3 neutralizing neutralize VBG cord-288072-42sx52tn 13 4 antibody antibody NN cord-288072-42sx52tn 13 5 were be VBD cord-288072-42sx52tn 13 6 usually usually RB cord-288072-42sx52tn 13 7 found find VBN cord-288072-42sx52tn 13 8 in in IN cord-288072-42sx52tn 13 9 pairs pair NNS cord-288072-42sx52tn 13 10 collected collect VBN cord-288072-42sx52tn 13 11 in in IN cord-288072-42sx52tn 13 12 1966 1966 CD cord-288072-42sx52tn 13 13 and and CC cord-288072-42sx52tn 13 14 1969 1969 CD cord-288072-42sx52tn 13 15 but but CC cord-288072-42sx52tn 13 16 not not RB cord-288072-42sx52tn 13 17 in in IN cord-288072-42sx52tn 13 18 those those DT cord-288072-42sx52tn 13 19 collected collect VBN cord-288072-42sx52tn 13 20 in in IN cord-288072-42sx52tn 13 21 1967 1967 CD cord-288072-42sx52tn 13 22 and and CC cord-288072-42sx52tn 13 23 1968 1968 CD cord-288072-42sx52tn 13 24 . . . cord-288072-42sx52tn 14 1 The the DT cord-288072-42sx52tn 14 2 infecting infect VBG cord-288072-42sx52tn 14 3 viruses virus NNS cord-288072-42sx52tn 14 4 in in IN cord-288072-42sx52tn 14 5 1966 1966 CD cord-288072-42sx52tn 14 6 and and CC cord-288072-42sx52tn 14 7 1969 1969 CD cord-288072-42sx52tn 14 8 thus thus RB cord-288072-42sx52tn 14 9 appeared appear VBD cord-288072-42sx52tn 14 10 more more RBR cord-288072-42sx52tn 14 11 closely closely RB cord-288072-42sx52tn 14 12 related related JJ cord-288072-42sx52tn 14 13 to to IN cord-288072-42sx52tn 14 14 OC43 OC43 NNP cord-288072-42sx52tn 14 15 than than IN cord-288072-42sx52tn 14 16 did do VBD cord-288072-42sx52tn 14 17 those those DT cord-288072-42sx52tn 14 18 in in IN cord-288072-42sx52tn 14 19 1967 1967 CD cord-288072-42sx52tn 14 20 and and CC cord-288072-42sx52tn 14 21 1968 1968 CD cord-288072-42sx52tn 14 22 . . . cord-288072-42sx52tn 15 1 Coronaviruses coronaviruse NNS cord-288072-42sx52tn 15 2 are be VBP cord-288072-42sx52tn 15 3 significantly significantly RB cord-288072-42sx52tn 15 4 involved involve VBN cord-288072-42sx52tn 15 5 in in IN cord-288072-42sx52tn 15 6 respiratory respiratory JJ cord-288072-42sx52tn 15 7 infections infection NNS cord-288072-42sx52tn 15 8 of of IN cord-288072-42sx52tn 15 9 man man NN cord-288072-42sx52tn 15 10 , , , cord-288072-42sx52tn 15 11 especially especially RB cord-288072-42sx52tn 15 12 in in IN cord-288072-42sx52tn 15 13 those those DT cord-288072-42sx52tn 15 14 occurring occur VBG cord-288072-42sx52tn 15 15 in in IN cord-288072-42sx52tn 15 16 the the DT cord-288072-42sx52tn 15 17 colder cold JJR cord-288072-42sx52tn 15 18 months month NNS cord-288072-42sx52tn 15 19 of of IN cord-288072-42sx52tn 15 20 the the DT cord-288072-42sx52tn 15 21 year year NN cord-288072-42sx52tn 15 22 [ [ -LRB- cord-288072-42sx52tn 15 23 1 1 CD cord-288072-42sx52tn 15 24 ] ] -RRB- cord-288072-42sx52tn 15 25 [ [ -LRB- cord-288072-42sx52tn 15 26 2 2 CD cord-288072-42sx52tn 15 27 ] ] -RRB- cord-288072-42sx52tn 15 28 [ [ -LRB- cord-288072-42sx52tn 15 29 3 3 CD cord-288072-42sx52tn 15 30 ] ] -RRB- cord-288072-42sx52tn 15 31 [ [ -LRB- cord-288072-42sx52tn 15 32 4 4 CD cord-288072-42sx52tn 15 33 ] ] -RRB- cord-288072-42sx52tn 15 34 . . . cord-288072-42sx52tn 16 1 However however RB cord-288072-42sx52tn 16 2 , , , cord-288072-42sx52tn 16 3 neither neither CC cord-288072-42sx52tn 16 4 the the DT cord-288072-42sx52tn 16 5 total total JJ cord-288072-42sx52tn 16 6 number number NN cord-288072-42sx52tn 16 7 of of IN cord-288072-42sx52tn 16 8 different different JJ cord-288072-42sx52tn 16 9 coronaviruses coronaviruse NNS cord-288072-42sx52tn 16 10 nor nor CC cord-288072-42sx52tn 16 11 their -PRON- PRP$ cord-288072-42sx52tn 16 12 relative relative JJ cord-288072-42sx52tn 16 13 importance importance NN cord-288072-42sx52tn 16 14 is be VBZ cord-288072-42sx52tn 16 15 known know VBN cord-288072-42sx52tn 16 16 . . . cord-288072-42sx52tn 17 1 Understanding understanding NN cord-288072-42sx52tn 17 2 of of IN cord-288072-42sx52tn 17 3 the the DT cord-288072-42sx52tn 17 4 behavior behavior NN cord-288072-42sx52tn 17 5 of of IN cord-288072-42sx52tn 17 6 these these DT cord-288072-42sx52tn 17 7 viruses virus NNS cord-288072-42sx52tn 17 8 has have VBZ cord-288072-42sx52tn 17 9 been be VBN cord-288072-42sx52tn 17 10 hampered hamper VBN cord-288072-42sx52tn 17 11 greatly greatly RB cord-288072-42sx52tn 17 12 by by IN cord-288072-42sx52tn 17 13 the the DT cord-288072-42sx52tn 17 14 difficulties difficulty NNS cord-288072-42sx52tn 17 15 in in IN cord-288072-42sx52tn 17 16 propagation propagation NN cord-288072-42sx52tn 17 17 encountered encounter VBN cord-288072-42sx52tn 17 18 in in IN cord-288072-42sx52tn 17 19 the the DT cord-288072-42sx52tn 17 20 laboratory laboratory NN cord-288072-42sx52tn 17 21 . . . cord-288072-42sx52tn 18 1 Only only RB cord-288072-42sx52tn 18 2 one one CD cord-288072-42sx52tn 18 3 coronavirus coronavirus NN cord-288072-42sx52tn 18 4 , , , cord-288072-42sx52tn 18 5 229E 229e CD cord-288072-42sx52tn 18 6 , , , cord-288072-42sx52tn 18 7 can can MD cord-288072-42sx52tn 18 8 be be VB cord-288072-42sx52tn 18 9 isolated isolate VBN cord-288072-42sx52tn 18 10 in in IN cord-288072-42sx52tn 18 11 cell cell NN cord-288072-42sx52tn 18 12 culture culture NN cord-288072-42sx52tn 18 13 , , , cord-288072-42sx52tn 18 14 and and CC cord-288072-42sx52tn 18 15 this this DT cord-288072-42sx52tn 18 16 is be VBZ cord-288072-42sx52tn 18 17 difficult difficult JJ cord-288072-42sx52tn 18 18 [ [ -LRB- cord-288072-42sx52tn 18 19 5 5 CD cord-288072-42sx52tn 18 20 ] ] -RRB- cord-288072-42sx52tn 18 21 . . . cord-288072-42sx52tn 19 1 A a DT cord-288072-42sx52tn 19 2 major major JJ cord-288072-42sx52tn 19 3 contribution contribution NN cord-288072-42sx52tn 19 4 has have VBZ cord-288072-42sx52tn 19 5 been be VBN cord-288072-42sx52tn 19 6 the the DT cord-288072-42sx52tn 19 7 adaptation adaptation NN cord-288072-42sx52tn 19 8 of of IN cord-288072-42sx52tn 19 9 viruses virus NNS cord-288072-42sx52tn 19 10 originally originally RB cord-288072-42sx52tn 19 11 isolated isolate VBN cord-288072-42sx52tn 19 12 in in IN cord-288072-42sx52tn 19 13 organ organ NN cord-288072-42sx52tn 19 14 culture culture NN cord-288072-42sx52tn 19 15 to to IN cord-288072-42sx52tn 19 16 animals animal NNS cord-288072-42sx52tn 19 17 or or CC cord-288072-42sx52tn 19 18 cell cell NN cord-288072-42sx52tn 19 19 cultures culture NNS cord-288072-42sx52tn 19 20 [ [ -LRB- cord-288072-42sx52tn 19 21 6 6 CD cord-288072-42sx52tn 19 22 , , , cord-288072-42sx52tn 19 23 7 7 CD cord-288072-42sx52tn 19 24 ] ] -RRB- cord-288072-42sx52tn 19 25 . . . cord-288072-42sx52tn 20 1 Several several JJ cord-288072-42sx52tn 20 2 serologic serologic NN cord-288072-42sx52tn 20 3 tests test NNS cord-288072-42sx52tn 20 4 have have VBP cord-288072-42sx52tn 20 5 thus thus RB cord-288072-42sx52tn 20 6 been be VBN cord-288072-42sx52tn 20 7 made make VBN cord-288072-42sx52tn 20 8 possible possible JJ cord-288072-42sx52tn 20 9 , , , cord-288072-42sx52tn 20 10 and and CC cord-288072-42sx52tn 20 11 infections infection NNS cord-288072-42sx52tn 20 12 can can MD cord-288072-42sx52tn 20 13 now now RB cord-288072-42sx52tn 20 14 be be VB cord-288072-42sx52tn 20 15 identified identify VBN cord-288072-42sx52tn 20 16 by by IN cord-288072-42sx52tn 20 17 rise rise NN cord-288072-42sx52tn 20 18 in in IN cord-288072-42sx52tn 20 19 antibody antibody NN cord-288072-42sx52tn 20 20 titer titer NN cord-288072-42sx52tn 20 21 [ [ -LRB- cord-288072-42sx52tn 20 22 8 8 CD cord-288072-42sx52tn 20 23 , , , cord-288072-42sx52tn 20 24 9 9 CD cord-288072-42sx52tn 20 25 ] ] -RRB- cord-288072-42sx52tn 20 26 . . . cord-288072-42sx52tn 21 1 As as IN cord-288072-42sx52tn 21 2 part part NN cord-288072-42sx52tn 21 3 of of IN cord-288072-42sx52tn 21 4 the the DT cord-288072-42sx52tn 21 5 study study NN cord-288072-42sx52tn 21 6 of of IN cord-288072-42sx52tn 21 7 respiratory respiratory JJ cord-288072-42sx52tn 21 8 infections infection NNS cord-288072-42sx52tn 21 9 in in IN cord-288072-42sx52tn 21 10 Tecumseh Tecumseh NNP cord-288072-42sx52tn 21 11 , , , cord-288072-42sx52tn 21 12 Michigan Michigan NNP cord-288072-42sx52tn 21 13 , , , cord-288072-42sx52tn 21 14 specimens specimen NNS cord-288072-42sx52tn 21 15 of of IN cord-288072-42sx52tn 21 16 blood blood NN cord-288072-42sx52tn 21 17 were be VBD cord-288072-42sx52tn 21 18 collected collect VBN cord-288072-42sx52tn 21 19 on on IN cord-288072-42sx52tn 21 20 a a DT cord-288072-42sx52tn 21 21 regular regular JJ cord-288072-42sx52tn 21 22 basis basis NN cord-288072-42sx52tn 21 23 from from IN cord-288072-42sx52tn 21 24 families family NNS cord-288072-42sx52tn 21 25 under under IN cord-288072-42sx52tn 21 26 surveillance surveillance NN cord-288072-42sx52tn 21 27 [ [ -LRB- cord-288072-42sx52tn 21 28 10 10 CD cord-288072-42sx52tn 21 29 ] ] -RRB- cord-288072-42sx52tn 21 30 . . . cord-288072-42sx52tn 22 1 By by IN cord-288072-42sx52tn 22 2 testing testing NN cord-288072-42sx52tn 22 3 of of IN cord-288072-42sx52tn 22 4 specimens specimen NNS cord-288072-42sx52tn 22 5 collected collect VBN cord-288072-42sx52tn 22 6 in in IN cord-288072-42sx52tn 22 7 early early JJ cord-288072-42sx52tn 22 8 1967 1967 CD cord-288072-42sx52tn 22 9 , , , cord-288072-42sx52tn 22 10 a a DT cord-288072-42sx52tn 22 11 large large JJ cord-288072-42sx52tn 22 12 - - HYPH cord-288072-42sx52tn 22 13 scale scale NN cord-288072-42sx52tn 22 14 outbreak outbreak NN cord-288072-42sx52tn 22 15 of of IN cord-288072-42sx52tn 22 16 infection infection NN cord-288072-42sx52tn 22 17 with with IN cord-288072-42sx52tn 22 18 coronavirus coronavirus NN cord-288072-42sx52tn 22 19 229E 229e CD cord-288072-42sx52tn 22 20 was be VBD cord-288072-42sx52tn 22 21 detected detect VBN cord-288072-42sx52tn 22 22 [ [ -LRB- cord-288072-42sx52tn 22 23 11 11 CD cord-288072-42sx52tn 22 24 ] ] -RRB- cord-288072-42sx52tn 22 25 . . . cord-288072-42sx52tn 23 1 All all DT cord-288072-42sx52tn 23 2 segments segment NNS cord-288072-42sx52tn 23 3 of of IN cord-288072-42sx52tn 23 4 the the DT cord-288072-42sx52tn 23 5 population population NN cord-288072-42sx52tn 23 6 were be VBD cord-288072-42sx52tn 23 7 involved involve VBN cord-288072-42sx52tn 23 8 , , , cord-288072-42sx52tn 23 9 and and CC cord-288072-42sx52tn 23 10 infection infection NN cord-288072-42sx52tn 23 11 was be VBD cord-288072-42sx52tn 23 12 significantly significantly RB cord-288072-42sx52tn 23 13 associated associate VBN cord-288072-42sx52tn 23 14 with with IN cord-288072-42sx52tn 23 15 respi respi JJ cord-288072-42sx52tn 23 16 - - HYPH cord-288072-42sx52tn 23 17 ratory ratory JJ cord-288072-42sx52tn 23 18 illness illness NN cord-288072-42sx52tn 23 19 . . . cord-288072-42sx52tn 24 1 Specimens specimen NNS cord-288072-42sx52tn 24 2 collected collect VBN cord-288072-42sx52tn 24 3 over over IN cord-288072-42sx52tn 24 4 four four CD cord-288072-42sx52tn 24 5 years year NNS cord-288072-42sx52tn 24 6 have have VBP cord-288072-42sx52tn 24 7 now now RB cord-288072-42sx52tn 24 8 been be VBN cord-288072-42sx52tn 24 9 tested test VBN cord-288072-42sx52tn 24 10 for for IN cord-288072-42sx52tn 24 11 infection infection NN cord-288072-42sx52tn 24 12 with with IN cord-288072-42sx52tn 24 13 coronavirus coronavirus NN cord-288072-42sx52tn 24 14 OC43 OC43 NNP cord-288072-42sx52tn 24 15 . . . cord-288072-42sx52tn 25 1 The the DT cord-288072-42sx52tn 25 2 present present JJ cord-288072-42sx52tn 25 3 report report NN cord-288072-42sx52tn 25 4 describes describe VBZ cord-288072-42sx52tn 25 5 the the DT cord-288072-42sx52tn 25 6 occurrence occurrence NN cord-288072-42sx52tn 25 7 of of IN cord-288072-42sx52tn 25 8 coronavirus coronavirus NN cord-288072-42sx52tn 25 9 infections infection NNS cord-288072-42sx52tn 25 10 during during IN cord-288072-42sx52tn 25 11 this this DT cord-288072-42sx52tn 25 12 period period NN cord-288072-42sx52tn 25 13 as as IN cord-288072-42sx52tn 25 14 determined determine VBN cord-288072-42sx52tn 25 15 by by IN cord-288072-42sx52tn 25 16 different different JJ cord-288072-42sx52tn 25 17 serologic serologic NN cord-288072-42sx52tn 25 18 techniques technique NNS cord-288072-42sx52tn 25 19 . . . cord-288072-42sx52tn 26 1 Population population NN cord-288072-42sx52tn 26 2 studied study VBD cord-288072-42sx52tn 26 3 and and CC cord-288072-42sx52tn 26 4 processing processing NN cord-288072-42sx52tn 26 5 of of IN cord-288072-42sx52tn 26 6 specimens specimen NNS cord-288072-42sx52tn 26 7 . . . cord-288072-42sx52tn 27 1 Details detail NNS cord-288072-42sx52tn 27 2 of of IN cord-288072-42sx52tn 27 3 the the DT cord-288072-42sx52tn 27 4 surveillance surveillance NN cord-288072-42sx52tn 27 5 methods method NNS cord-288072-42sx52tn 27 6 used use VBN cord-288072-42sx52tn 27 7 in in IN cord-288072-42sx52tn 27 8 Tecumseh Tecumseh NNP cord-288072-42sx52tn 27 9 have have VBP cord-288072-42sx52tn 27 10 been be VBN cord-288072-42sx52tn 27 11 described describe VBN cord-288072-42sx52tn 27 12 [ [ -LRB- cord-288072-42sx52tn 27 13 12 12 CD cord-288072-42sx52tn 27 14 ] ] -RRB- cord-288072-42sx52tn 27 15 . . . cord-288072-42sx52tn 28 1 Families family NNS cord-288072-42sx52tn 28 2 for for IN cord-288072-42sx52tn 28 3 study study NN cord-288072-42sx52tn 28 4 were be VBD cord-288072-42sx52tn 28 5 selected select VBN cord-288072-42sx52tn 28 6 randomly randomly RB cord-288072-42sx52tn 28 7 from from IN cord-288072-42sx52tn 28 8 those those DT cord-288072-42sx52tn 28 9 with with IN cord-288072-42sx52tn 28 10 children child NNS cord-288072-42sx52tn 28 11 whose whose WP$ cord-288072-42sx52tn 28 12 parents parent NNS cord-288072-42sx52tn 28 13 were be VBD cord-288072-42sx52tn 28 14 under under IN cord-288072-42sx52tn 28 15 46 46 CD cord-288072-42sx52tn 28 16 years year NNS cord-288072-42sx52tn 28 17 of of IN cord-288072-42sx52tn 28 18 age age NN cord-288072-42sx52tn 28 19 . . . cord-288072-42sx52tn 29 1 Each each DT cord-288072-42sx52tn 29 2 family family NN cord-288072-42sx52tn 29 3 was be VBD cord-288072-42sx52tn 29 4 followed follow VBN cord-288072-42sx52tn 29 5 for for IN cord-288072-42sx52tn 29 6 one one CD cord-288072-42sx52tn 29 7 year year NN cord-288072-42sx52tn 29 8 . . . cord-288072-42sx52tn 30 1 Specimens specimen NNS cord-288072-42sx52tn 30 2 were be VBD cord-288072-42sx52tn 30 3 obtained obtain VBN cord-288072-42sx52tn 30 4 for for IN cord-288072-42sx52tn 30 5 isolation isolation NN cord-288072-42sx52tn 30 6 of of IN cord-288072-42sx52tn 30 7 virus virus NN cord-288072-42sx52tn 30 8 when when WRB cord-288072-42sx52tn 30 9 a a DT cord-288072-42sx52tn 30 10 respiratory respiratory JJ cord-288072-42sx52tn 30 11 illness illness NN cord-288072-42sx52tn 30 12 was be VBD cord-288072-42sx52tn 30 13 reported report VBN cord-288072-42sx52tn 30 14 within within IN cord-288072-42sx52tn 30 15 two two CD cord-288072-42sx52tn 30 16 days day NNS cord-288072-42sx52tn 30 17 of of IN cord-288072-42sx52tn 30 18 onset onset NN cord-288072-42sx52tn 30 19 [ [ -LRB- cord-288072-42sx52tn 30 20 13 13 CD cord-288072-42sx52tn 30 21 ] ] -RRB- cord-288072-42sx52tn 30 22 . . . cord-288072-42sx52tn 31 1 Samples sample NNS cord-288072-42sx52tn 31 2 of of IN cord-288072-42sx52tn 31 3 blood blood NN cord-288072-42sx52tn 31 4 were be VBD cord-288072-42sx52tn 31 5 collected collect VBN cord-288072-42sx52tn 31 6 at at IN cord-288072-42sx52tn 31 7 time time NN cord-288072-42sx52tn 31 8 of of IN cord-288072-42sx52tn 31 9 recruitment recruitment NN cord-288072-42sx52tn 31 10 , , , cord-288072-42sx52tn 31 11 six six CD cord-288072-42sx52tn 31 12 months month NNS cord-288072-42sx52tn 31 13 later later RB cord-288072-42sx52tn 31 14 , , , cord-288072-42sx52tn 31 15 and and CC cord-288072-42sx52tn 31 16 at at IN cord-288072-42sx52tn 31 17 the the DT cord-288072-42sx52tn 31 18 end end NN cord-288072-42sx52tn 31 19 of of IN cord-288072-42sx52tn 31 20 the the DT cord-288072-42sx52tn 31 21 year year NN cord-288072-42sx52tn 31 22 of of IN cord-288072-42sx52tn 31 23 surveillance surveillance NN cord-288072-42sx52tn 31 24 [ [ -LRB- cord-288072-42sx52tn 31 25 10 10 CD cord-288072-42sx52tn 31 26 ] ] -RRB- cord-288072-42sx52tn 31 27 . . . cord-288072-42sx52tn 32 1 Because because IN cord-288072-42sx52tn 32 2 recruitment recruitment NN cord-288072-42sx52tn 32 3 of of IN cord-288072-42sx52tn 32 4 families family NNS cord-288072-42sx52tn 32 5 was be VBD cord-288072-42sx52tn 32 6 staggered stagger VBN cord-288072-42sx52tn 32 7 , , , cord-288072-42sx52tn 32 8 specimens specimen NNS cord-288072-42sx52tn 32 9 of of IN cord-288072-42sx52tn 32 10 blood blood NN cord-288072-42sx52tn 32 11 were be VBD cord-288072-42sx52tn 32 12 collected collect VBN cord-288072-42sx52tn 32 13 during during IN cord-288072-42sx52tn 32 14 all all DT cord-288072-42sx52tn 32 15 months month NNS cord-288072-42sx52tn 32 16 of of IN cord-288072-42sx52tn 32 17 the the DT cord-288072-42sx52tn 32 18 year year NN cord-288072-42sx52tn 32 19 . . . cord-288072-42sx52tn 33 1 Blood blood NN cord-288072-42sx52tn 33 2 was be VBD cord-288072-42sx52tn 33 3 drawn draw VBN cord-288072-42sx52tn 33 4 by by IN cord-288072-42sx52tn 33 5 venipuncture venipuncture NN cord-288072-42sx52tn 33 6 from from IN cord-288072-42sx52tn 33 7 individuals individual NNS cord-288072-42sx52tn 33 8 of of IN cord-288072-42sx52tn 33 9 approximately approximately RB cord-288072-42sx52tn 33 10 five five CD cord-288072-42sx52tn 33 11 years year NNS cord-288072-42sx52tn 33 12 of of IN cord-288072-42sx52tn 33 13 age age NN cord-288072-42sx52tn 33 14 and and CC cord-288072-42sx52tn 33 15 older old JJR cord-288072-42sx52tn 33 16 , , , cord-288072-42sx52tn 33 17 and and CC cord-288072-42sx52tn 33 18 the the DT cord-288072-42sx52tn 33 19 specimens specimen NNS cord-288072-42sx52tn 33 20 of of IN cord-288072-42sx52tn 33 21 serum serum NN cord-288072-42sx52tn 33 22 were be VBD cord-288072-42sx52tn 33 23 stored store VBN cord-288072-42sx52tn 33 24 at at IN cord-288072-42sx52tn 33 25 -20 -20 CD cord-288072-42sx52tn 33 26 C. c. NN cord-288072-42sx52tn 34 1 The the DT cord-288072-42sx52tn 34 2 specimens specimen NNS cord-288072-42sx52tn 34 3 were be VBD cord-288072-42sx52tn 34 4 collected collect VBN cord-288072-42sx52tn 34 5 from from IN cord-288072-42sx52tn 34 6 younger young JJR cord-288072-42sx52tn 34 7 children child NNS cord-288072-42sx52tn 34 8 on on IN cord-288072-42sx52tn 34 9 filter filter NN cord-288072-42sx52tn 34 10 paper paper NN cord-288072-42sx52tn 34 11 disks disk NNS cord-288072-42sx52tn 34 12 by by IN cord-288072-42sx52tn 34 13 finger finger NN cord-288072-42sx52tn 34 14 stick stick NN cord-288072-42sx52tn 34 15 . . . cord-288072-42sx52tn 35 1 At at RB cord-288072-42sx52tn 35 2 least least JJS cord-288072-42sx52tn 35 3 four four CD cord-288072-42sx52tn 35 4 disks disk NNS cord-288072-42sx52tn 35 5 were be VBD cord-288072-42sx52tn 35 6 obtained obtain VBN cord-288072-42sx52tn 35 7 at at IN cord-288072-42sx52tn 35 8 one one CD cord-288072-42sx52tn 35 9 time time NN cord-288072-42sx52tn 35 10 , , , cord-288072-42sx52tn 35 11 and and CC cord-288072-42sx52tn 35 12 they -PRON- PRP cord-288072-42sx52tn 35 13 were be VBD cord-288072-42sx52tn 35 14 dried dry VBN cord-288072-42sx52tn 35 15 and and CC cord-288072-42sx52tn 35 16 stored store VBN cord-288072-42sx52tn 35 17 at at IN cord-288072-42sx52tn 35 18 4 4 CD cord-288072-42sx52tn 35 19 C c NN cord-288072-42sx52tn 35 20 until until IN cord-288072-42sx52tn 35 21 use use NN cord-288072-42sx52tn 35 22 . . . cord-288072-42sx52tn 36 1 For for IN cord-288072-42sx52tn 36 2 CF CF NNP cord-288072-42sx52tn 36 3 and and CC cord-288072-42sx52tn 36 4 HAl hal JJ cord-288072-42sx52tn 36 5 tests test NNS cord-288072-42sx52tn 36 6 , , , cord-288072-42sx52tn 36 7 two two CD cord-288072-42sx52tn 36 8 disks disk NNS cord-288072-42sx52tn 36 9 were be VBD cord-288072-42sx52tn 36 10 placed place VBN cord-288072-42sx52tn 36 11 in in IN cord-288072-42sx52tn 36 12 0.5 0.5 CD cord-288072-42sx52tn 36 13 ml ml NNS cord-288072-42sx52tn 36 14 of of IN cord-288072-42sx52tn 36 15 veronal veronal JJ cord-288072-42sx52tn 36 16 - - HYPH cord-288072-42sx52tn 36 17 buflered buflered JJ cord-288072-42sx52tn 36 18 saline saline NN cord-288072-42sx52tn 36 19 , , , cord-288072-42sx52tn 36 20 and and CC cord-288072-42sx52tn 36 21 the the DT cord-288072-42sx52tn 36 22 blood blood NN cord-288072-42sx52tn 36 23 was be VBD cord-288072-42sx52tn 36 24 eluted elute VBN cord-288072-42sx52tn 36 25 for for IN cord-288072-42sx52tn 36 26 18 18 CD cord-288072-42sx52tn 36 27 hr hr NN cord-288072-42sx52tn 36 28 at at IN cord-288072-42sx52tn 36 29 4 4 CD cord-288072-42sx52tn 36 30 C. C. NNP cord-288072-42sx52tn 36 31 Thereafter Thereafter NNP cord-288072-42sx52tn 36 32 , , , cord-288072-42sx52tn 36 33 the the DT cord-288072-42sx52tn 36 34 fluid fluid NN cord-288072-42sx52tn 36 35 was be VBD cord-288072-42sx52tn 36 36 completely completely RB cord-288072-42sx52tn 36 37 expressed express VBN cord-288072-42sx52tn 36 38 from from IN cord-288072-42sx52tn 36 39 the the DT cord-288072-42sx52tn 36 40 disks disk NNS cord-288072-42sx52tn 36 41 and and CC cord-288072-42sx52tn 36 42 inactivated inactivate VBD cord-288072-42sx52tn 36 43 at at IN cord-288072-42sx52tn 36 44 56 56 CD cord-288072-42sx52tn 36 45 C c NN cord-288072-42sx52tn 36 46 for for IN cord-288072-42sx52tn 36 47 30 30 CD cord-288072-42sx52tn 36 48 min min NN cord-288072-42sx52tn 36 49 . . . cord-288072-42sx52tn 37 1 The the DT cord-288072-42sx52tn 37 2 eluate eluate NN cord-288072-42sx52tn 37 3 was be VBD cord-288072-42sx52tn 37 4 centrifuged centrifuge VBN cord-288072-42sx52tn 37 5 for for IN cord-288072-42sx52tn 37 6 1 1 CD cord-288072-42sx52tn 37 7 hr hr NN cord-288072-42sx52tn 37 8 at at IN cord-288072-42sx52tn 37 9 650 650 CD cord-288072-42sx52tn 37 10 g g NN cord-288072-42sx52tn 37 11 , , , cord-288072-42sx52tn 37 12 and and CC cord-288072-42sx52tn 37 13 the the DT cord-288072-42sx52tn 37 14 supernatant supernatant NN cord-288072-42sx52tn 37 15 was be VBD cord-288072-42sx52tn 37 16 considered consider VBN cord-288072-42sx52tn 37 17 to to TO cord-288072-42sx52tn 37 18 represent represent VB cord-288072-42sx52tn 37 19 a a DT cord-288072-42sx52tn 37 20 1:4 1:4 CD cord-288072-42sx52tn 37 21 dilution dilution NN cord-288072-42sx52tn 37 22 . . . cord-288072-42sx52tn 38 1 The the DT cord-288072-42sx52tn 38 2 specimens specimen NNS cord-288072-42sx52tn 38 3 of of IN cord-288072-42sx52tn 38 4 serum serum NN cord-288072-42sx52tn 38 5 were be VBD cord-288072-42sx52tn 38 6 inactivated inactivate VBN cord-288072-42sx52tn 38 7 at at IN cord-288072-42sx52tn 38 8 56 56 CD cord-288072-42sx52tn 38 9 C c NN cord-288072-42sx52tn 38 10 for for IN cord-288072-42sx52tn 38 11 30 30 CD cord-288072-42sx52tn 38 12 min min NN cord-288072-42sx52tn 38 13 before before IN cord-288072-42sx52tn 38 14 dilution dilution NN cord-288072-42sx52tn 38 15 for for IN cord-288072-42sx52tn 38 16 CF CF NNP cord-288072-42sx52tn 38 17 , , , cord-288072-42sx52tn 38 18 HAl HAl NNPS cord-288072-42sx52tn 38 19 , , , cord-288072-42sx52tn 38 20 or or CC cord-288072-42sx52tn 38 21 neutralization neutralization NN cord-288072-42sx52tn 38 22 tests test NNS cord-288072-42sx52tn 38 23 . . . cord-288072-42sx52tn 39 1 A a DT cord-288072-42sx52tn 39 2 ntigens ntigens NN cord-288072-42sx52tn 39 3 used use VBN cord-288072-42sx52tn 39 4 . . . cord-288072-42sx52tn 40 1 OC43 OC43 NNP cord-288072-42sx52tn 40 2 antigen antigen NN cord-288072-42sx52tn 40 3 was be VBD cord-288072-42sx52tn 40 4 prepared prepare VBN cord-288072-42sx52tn 40 5 from from IN cord-288072-42sx52tn 40 6 a a DT cord-288072-42sx52tn 40 7 mouse mouse NN cord-288072-42sx52tn 40 8 brain brain NN cord-288072-42sx52tn 40 9 - - HYPH cord-288072-42sx52tn 40 10 adapted adapt VBN cord-288072-42sx52tn 40 11 strain strain NN cord-288072-42sx52tn 40 12 obtained obtain VBN cord-288072-42sx52tn 40 13 through through IN cord-288072-42sx52tn 40 14 the the DT cord-288072-42sx52tn 40 15 courtesy courtesy NN cord-288072-42sx52tn 40 16 of of IN cord-288072-42sx52tn 40 17 Mr. Mr. NNP cord-288072-42sx52tn 40 18 H. H. NNP cord-288072-42sx52tn 40 19 S. S. NNP cord-288072-42sx52tn 40 20 Kaye Kaye NNP cord-288072-42sx52tn 40 21 , , , cord-288072-42sx52tn 40 22 Center Center NNP cord-288072-42sx52tn 40 23 for for IN cord-288072-42sx52tn 40 24 Disease Disease NNP cord-288072-42sx52tn 40 25 Control Control NNP cord-288072-42sx52tn 40 26 . . . cord-288072-42sx52tn 41 1 The the DT cord-288072-42sx52tn 41 2 seed seed NN cord-288072-42sx52tn 41 3 was be VBD cord-288072-42sx52tn 41 4 propagated propagate VBN cord-288072-42sx52tn 41 5 by by IN cord-288072-42sx52tn 41 6 intracerebral intracerebral JJ cord-288072-42sx52tn 41 7 inoculation inoculation NN cord-288072-42sx52tn 41 8 of of IN cord-288072-42sx52tn 41 9 suckling suckle VBG cord-288072-42sx52tn 41 10 mice mouse NNS cord-288072-42sx52tn 41 11 . . . cord-288072-42sx52tn 42 1 Antigen Antigen NNP cord-288072-42sx52tn 42 2 was be VBD cord-288072-42sx52tn 42 3 prepared prepare VBN cord-288072-42sx52tn 42 4 as as IN cord-288072-42sx52tn 42 5 a a DT cord-288072-42sx52tn 42 6 10 10 CD cord-288072-42sx52tn 42 7 % % NN cord-288072-42sx52tn 42 8 suspension suspension NN cord-288072-42sx52tn 42 9 , , , cord-288072-42sx52tn 42 10 in in IN cord-288072-42sx52tn 42 11 phosphatebuffered phosphatebuffered JJ cord-288072-42sx52tn 42 12 saline saline NN cord-288072-42sx52tn 42 13 for for IN cord-288072-42sx52tn 42 14 HAl hal JJ cord-288072-42sx52tn 42 15 tests test NNS cord-288072-42sx52tn 42 16 , , , cord-288072-42sx52tn 42 17 and and CC cord-288072-42sx52tn 42 18 in in IN cord-288072-42sx52tn 42 19 tryptose tryptose JJ cord-288072-42sx52tn 42 20 - - HYPH cord-288072-42sx52tn 42 21 phosphate phosphate NN cord-288072-42sx52tn 42 22 broth broth NN cord-288072-42sx52tn 42 23 for for IN cord-288072-42sx52tn 42 24 neutralization neutralization NN cord-288072-42sx52tn 42 25 tests test NNS cord-288072-42sx52tn 42 26 . . . cord-288072-42sx52tn 43 1 For for IN cord-288072-42sx52tn 43 2 CF cf NN cord-288072-42sx52tn 43 3 tests test NNS cord-288072-42sx52tn 43 4 , , , cord-288072-42sx52tn 43 5 antigen antigen NNP cord-288072-42sx52tn 43 6 was be VBD cord-288072-42sx52tn 43 7 prepared prepare VBN cord-288072-42sx52tn 43 8 as as IN cord-288072-42sx52tn 43 9 a a DT cord-288072-42sx52tn 43 10 20 20 CD cord-288072-42sx52tn 43 11 % % NN cord-288072-42sx52tn 43 12 suspension suspension NN cord-288072-42sx52tn 43 13 in in IN cord-288072-42sx52tn 43 14 veronal veronal JJ cord-288072-42sx52tn 43 15 - - HYPH cord-288072-42sx52tn 43 16 buffered buffer VBN cord-288072-42sx52tn 43 17 saline saline NN cord-288072-42sx52tn 43 18 . . . cord-288072-42sx52tn 44 1 The the DT cord-288072-42sx52tn 44 2 identity identity NN cord-288072-42sx52tn 44 3 of of IN cord-288072-42sx52tn 44 4 each each DT cord-288072-42sx52tn 44 5 pool pool NN cord-288072-42sx52tn 44 6 of of IN cord-288072-42sx52tn 44 7 virus virus NN cord-288072-42sx52tn 44 8 was be VBD cord-288072-42sx52tn 44 9 confirmed confirm VBN cord-288072-42sx52tn 44 10 by by IN cord-288072-42sx52tn 44 11 CF CF NNP cord-288072-42sx52tn 44 12 with with IN cord-288072-42sx52tn 44 13 a a DT cord-288072-42sx52tn 44 14 homologous homologous JJ cord-288072-42sx52tn 44 15 and and CC cord-288072-42sx52tn 44 16 a a DT cord-288072-42sx52tn 44 17 hyperimmune hyperimmune NNP cord-288072-42sx52tn 44 18 antiserum antiserum NN cord-288072-42sx52tn 44 19 to to IN cord-288072-42sx52tn 44 20 murine murine JJ cord-288072-42sx52tn 44 21 hepatitis hepatitis NN cord-288072-42sx52tn 44 22 virus virus NN cord-288072-42sx52tn 44 23 . . . cord-288072-42sx52tn 45 1 The the DT cord-288072-42sx52tn 45 2 seed seed NN cord-288072-42sx52tn 45 3 of of IN cord-288072-42sx52tn 45 4 229E 229e CD cord-288072-42sx52tn 45 5 virus virus NN cord-288072-42sx52tn 45 6 was be VBD cord-288072-42sx52tn 45 7 originally originally RB cord-288072-42sx52tn 45 8 obtained obtain VBN cord-288072-42sx52tn 45 9 from from IN cord-288072-42sx52tn 45 10 Dr. Dr. NNP cord-288072-42sx52tn 45 11 Dorothy Dorothy NNP cord-288072-42sx52tn 45 12 Hamre Hamre NNP cord-288072-42sx52tn 45 13 and and CC cord-288072-42sx52tn 45 14 was be VBD cord-288072-42sx52tn 45 15 passed pass VBN cord-288072-42sx52tn 45 16 serially serially RB cord-288072-42sx52tn 45 17 in in IN cord-288072-42sx52tn 45 18 WI-38 WI-38 NNP cord-288072-42sx52tn 45 19 cell cell NN cord-288072-42sx52tn 45 20 culture culture NN cord-288072-42sx52tn 45 21 . . . cord-288072-42sx52tn 46 1 Antigen Antigen NNP cord-288072-42sx52tn 46 2 for for IN cord-288072-42sx52tn 46 3 CF cf NN cord-288072-42sx52tn 46 4 tests test NNS cord-288072-42sx52tn 46 5 was be VBD cord-288072-42sx52tn 46 6 prepared prepare VBN cord-288072-42sx52tn 46 7 by by IN cord-288072-42sx52tn 46 8 inoculation inoculation NN cord-288072-42sx52tn 46 9 of of IN cord-288072-42sx52tn 46 10 WI-38 WI-38 NNP cord-288072-42sx52tn 46 11 bottles bottle NNS cord-288072-42sx52tn 46 12 or or CC cord-288072-42sx52tn 46 13 tubes tube NNS cord-288072-42sx52tn 46 14 with with IN cord-288072-42sx52tn 46 15 undiluted undiluted JJ cord-288072-42sx52tn 46 16 virus virus NN cord-288072-42sx52tn 46 17 . . . cord-288072-42sx52tn 47 1 After after IN cord-288072-42sx52tn 47 2 incubation incubation NN cord-288072-42sx52tn 47 3 for for IN cord-288072-42sx52tn 47 4 34 34 CD cord-288072-42sx52tn 47 5 - - SYM cord-288072-42sx52tn 47 6 38 38 CD cord-288072-42sx52tn 47 7 hr hr NN cord-288072-42sx52tn 47 8 at at IN cord-288072-42sx52tn 47 9 33 33 CD cord-288072-42sx52tn 47 10 C c NN cord-288072-42sx52tn 47 11 the the DT cord-288072-42sx52tn 47 12 cultures culture NNS cord-288072-42sx52tn 47 13 were be VBD cord-288072-42sx52tn 47 14 frozen freeze VBN cord-288072-42sx52tn 47 15 and and CC cord-288072-42sx52tn 47 16 thawed thaw VBN cord-288072-42sx52tn 47 17 three three CD cord-288072-42sx52tn 47 18 times time NNS cord-288072-42sx52tn 47 19 , , , cord-288072-42sx52tn 47 20 fluids fluid NNS cord-288072-42sx52tn 47 21 were be VBD cord-288072-42sx52tn 47 22 centrifuged centrifuge VBN cord-288072-42sx52tn 47 23 , , , cord-288072-42sx52tn 47 24 and and CC cord-288072-42sx52tn 47 25 the the DT cord-288072-42sx52tn 47 26 supernatant supernatant NN cord-288072-42sx52tn 47 27 was be VBD cord-288072-42sx52tn 47 28 used use VBN cord-288072-42sx52tn 47 29 as as IN cord-288072-42sx52tn 47 30 antigen antigen NN cord-288072-42sx52tn 47 31 [ [ -LRB- cord-288072-42sx52tn 47 32 11 11 CD cord-288072-42sx52tn 47 33 ] ] -RRB- cord-288072-42sx52tn 47 34 . . . cord-288072-42sx52tn 48 1 Serologic Serologic NNP cord-288072-42sx52tn 48 2 tests test NNS cord-288072-42sx52tn 48 3 . . . cord-288072-42sx52tn 49 1 CF CF NNP cord-288072-42sx52tn 49 2 and and CC cord-288072-42sx52tn 49 3 HAl hal JJ cord-288072-42sx52tn 49 4 tests test NNS cord-288072-42sx52tn 49 5 were be VBD cord-288072-42sx52tn 49 6 performed perform VBN cord-288072-42sx52tn 49 7 on on IN cord-288072-42sx52tn 49 8 all all DT cord-288072-42sx52tn 49 9 specimens specimen NNS cord-288072-42sx52tn 49 10 of of IN cord-288072-42sx52tn 49 11 serum serum NN cord-288072-42sx52tn 49 12 collected collect VBN cord-288072-42sx52tn 49 13 from from IN cord-288072-42sx52tn 49 14 members member NNS cord-288072-42sx52tn 49 15 of of IN cord-288072-42sx52tn 49 16 269 269 CD cord-288072-42sx52tn 49 17 families family NNS cord-288072-42sx52tn 49 18 . . . cord-288072-42sx52tn 50 1 These these DT cord-288072-42sx52tn 50 2 families family NNS cord-288072-42sx52tn 50 3 were be VBD cord-288072-42sx52tn 50 4 selected select VBN cord-288072-42sx52tn 50 5 randomly randomly RB cord-288072-42sx52tn 50 6 from from IN cord-288072-42sx52tn 50 7 within within IN cord-288072-42sx52tn 50 8 each each DT cord-288072-42sx52tn 50 9 of of IN cord-288072-42sx52tn 50 10 the the DT cord-288072-42sx52tn 50 11 four four CD cord-288072-42sx52tn 50 12 years year NNS cord-288072-42sx52tn 50 13 of of IN cord-288072-42sx52tn 50 14 study study NN cord-288072-42sx52tn 50 15 so so IN cord-288072-42sx52tn 50 16 that that IN cord-288072-42sx52tn 50 17 all all DT cord-288072-42sx52tn 50 18 periods period NNS cord-288072-42sx52tn 50 19 would would MD cord-288072-42sx52tn 50 20 be be VB cord-288072-42sx52tn 50 21 represented represent VBN cord-288072-42sx52tn 50 22 . . . cord-288072-42sx52tn 51 1 The the DT cord-288072-42sx52tn 51 2 standard standard JJ cord-288072-42sx52tn 51 3 CF cf NN cord-288072-42sx52tn 51 4 test test NN cord-288072-42sx52tn 51 5 was be VBD cord-288072-42sx52tn 51 6 performed perform VBN cord-288072-42sx52tn 51 7 by by IN cord-288072-42sx52tn 51 8 a a DT cord-288072-42sx52tn 51 9 microplate microplate JJ cord-288072-42sx52tn 51 10 technique technique NN cord-288072-42sx52tn 51 11 with with IN cord-288072-42sx52tn 51 12 sheep sheep NN cord-288072-42sx52tn 51 13 erythrocytes erythrocyte NNS cord-288072-42sx52tn 51 14 , , , cord-288072-42sx52tn 51 15 4 4 CD cord-288072-42sx52tn 51 16 units unit NNS cord-288072-42sx52tn 51 17 of of IN cord-288072-42sx52tn 51 18 antigen antigen NN cord-288072-42sx52tn 51 19 , , , cord-288072-42sx52tn 51 20 and and CC cord-288072-42sx52tn 51 21 1.8 1.8 CD cord-288072-42sx52tn 51 22 units unit NNS cord-288072-42sx52tn 51 23 of of IN cord-288072-42sx52tn 51 24 complement complement NN cord-288072-42sx52tn 51 25 . . . cord-288072-42sx52tn 52 1 The the DT cord-288072-42sx52tn 52 2 HAl hal JJ cord-288072-42sx52tn 52 3 test test NN cord-288072-42sx52tn 52 4 was be VBD cord-288072-42sx52tn 52 5 performed perform VBN cord-288072-42sx52tn 52 6 in in IN cord-288072-42sx52tn 52 7 microplates microplate NNS cord-288072-42sx52tn 52 8 by by IN cord-288072-42sx52tn 52 9 the the DT cord-288072-42sx52tn 52 10 method method NN cord-288072-42sx52tn 52 11 of of IN cord-288072-42sx52tn 52 12 Kaye Kaye NNP cord-288072-42sx52tn 52 13 et et NNP cord-288072-42sx52tn 52 14 al al NNP cord-288072-42sx52tn 52 15 . . . cord-288072-42sx52tn 53 1 [ [ -LRB- cord-288072-42sx52tn 53 2 8 8 CD cord-288072-42sx52tn 53 3 ] ] -RRB- cord-288072-42sx52tn 53 4 . . . cord-288072-42sx52tn 54 1 Sera Sera NNP cord-288072-42sx52tn 54 2 were be VBD cord-288072-42sx52tn 54 3 serially serially RB cord-288072-42sx52tn 54 4 diluted dilute VBN cord-288072-42sx52tn 54 5 in in IN cord-288072-42sx52tn 54 6 phosphate phosphate NN cord-288072-42sx52tn 54 7 buffered buffer VBN cord-288072-42sx52tn 54 8 saline saline NN cord-288072-42sx52tn 54 9 from from IN cord-288072-42sx52tn 54 10 the the DT cord-288072-42sx52tn 54 11 initial initial JJ cord-288072-42sx52tn 54 12 1 1 CD cord-288072-42sx52tn 54 13 : : SYM cord-288072-42sx52tn 54 14 4 4 CD cord-288072-42sx52tn 54 15 dilution dilution NN cord-288072-42sx52tn 54 16 , , , cord-288072-42sx52tn 54 17 and and CC cord-288072-42sx52tn 54 18 4 4 CD cord-288072-42sx52tn 54 19 units unit NNS cord-288072-42sx52tn 54 20 of of IN cord-288072-42sx52tn 54 21 antigen antigen NN cord-288072-42sx52tn 54 22 were be VBD cord-288072-42sx52tn 54 23 added add VBN cord-288072-42sx52tn 54 24 . . . cord-288072-42sx52tn 55 1 After after IN cord-288072-42sx52tn 55 2 incubation incubation NN cord-288072-42sx52tn 55 3 for for IN cord-288072-42sx52tn 55 4 30 30 CD cord-288072-42sx52tn 55 5 min min NN cord-288072-42sx52tn 55 6 at at IN cord-288072-42sx52tn 55 7 24 24 CD cord-288072-42sx52tn 55 8 C C NNP cord-288072-42sx52tn 55 9 0.4 0.4 CD cord-288072-42sx52tn 55 10 % % NN cord-288072-42sx52tn 55 11 chick chick NN cord-288072-42sx52tn 55 12 erythrocytes erythrocyte NNS cord-288072-42sx52tn 55 13 were be VBD cord-288072-42sx52tn 55 14 added add VBN cord-288072-42sx52tn 55 15 . . . cord-288072-42sx52tn 56 1 The the DT cord-288072-42sx52tn 56 2 test test NN cord-288072-42sx52tn 56 3 was be VBD cord-288072-42sx52tn 56 4 read read VBN cord-288072-42sx52tn 56 5 after after IN cord-288072-42sx52tn 56 6 incubation incubation NN cord-288072-42sx52tn 56 7 for for IN cord-288072-42sx52tn 56 8 an an DT cord-288072-42sx52tn 56 9 additional additional JJ cord-288072-42sx52tn 56 10 1 1 CD cord-288072-42sx52tn 56 11 hr hr NN cord-288072-42sx52tn 56 12 at at IN cord-288072-42sx52tn 56 13 24 24 CD cord-288072-42sx52tn 56 14 C. C. NNP cord-288072-42sx52tn 56 15 For for IN cord-288072-42sx52tn 56 16 both both DT cord-288072-42sx52tn 56 17 CF CF NNP cord-288072-42sx52tn 56 18 and and CC cord-288072-42sx52tn 56 19 HAl HAl NNP cord-288072-42sx52tn 56 20 , , , cord-288072-42sx52tn 56 21 all all DT cord-288072-42sx52tn 56 22 sera sera NNP cord-288072-42sx52tn 56 23 from from IN cord-288072-42sx52tn 56 24 the the DT cord-288072-42sx52tn 56 25 same same JJ cord-288072-42sx52tn 56 26 individual individual NN cord-288072-42sx52tn 56 27 were be VBD cord-288072-42sx52tn 56 28 tested test VBN cord-288072-42sx52tn 56 29 simultaneously simultaneously RB cord-288072-42sx52tn 56 30 . . . cord-288072-42sx52tn 57 1 A a DT cord-288072-42sx52tn 57 2 significant significant JJ cord-288072-42sx52tn 57 3 rise rise NN cord-288072-42sx52tn 57 4 in in IN cord-288072-42sx52tn 57 5 titer titer NN cord-288072-42sx52tn 57 6 was be VBD cord-288072-42sx52tn 57 7 considered consider VBN cord-288072-42sx52tn 57 8 to to TO cord-288072-42sx52tn 57 9 have have VB cord-288072-42sx52tn 57 10 occurred occur VBN cord-288072-42sx52tn 57 11 if if IN cord-288072-42sx52tn 57 12 antibody antibody NN cord-288072-42sx52tn 57 13 appeared appear VBD cord-288072-42sx52tn 57 14 in in IN cord-288072-42sx52tn 57 15 a a DT cord-288072-42sx52tn 57 16 1 1 CD cord-288072-42sx52tn 57 17 : : SYM cord-288072-42sx52tn 57 18 8 8 CD cord-288072-42sx52tn 57 19 dilution dilution NN cord-288072-42sx52tn 57 20 when when WRB cord-288072-42sx52tn 57 21 prior prior JJ cord-288072-42sx52tn 57 22 specimens specimen NNS cord-288072-42sx52tn 57 23 did do VBD cord-288072-42sx52tn 57 24 not not RB cord-288072-42sx52tn 57 25 have have VB cord-288072-42sx52tn 57 26 demonstrable demonstrable JJ cord-288072-42sx52tn 57 27 antibody antibody NN cord-288072-42sx52tn 57 28 at at IN cord-288072-42sx52tn 57 29 a a DT cord-288072-42sx52tn 57 30 1 1 CD cord-288072-42sx52tn 57 31 : : SYM cord-288072-42sx52tn 57 32 4 4 CD cord-288072-42sx52tn 57 33 dilution dilution NN cord-288072-42sx52tn 57 34 . . . cord-288072-42sx52tn 58 1 A a DT cord-288072-42sx52tn 58 2 fourfold fourfold JJ cord-288072-42sx52tn 58 3 rise rise NN cord-288072-42sx52tn 58 4 from from IN cord-288072-42sx52tn 58 5 a a DT cord-288072-42sx52tn 58 6 previous previous JJ cord-288072-42sx52tn 58 7 antibody antibody NN cord-288072-42sx52tn 58 8 titer titer NN cord-288072-42sx52tn 58 9 was be VBD cord-288072-42sx52tn 58 10 also also RB cord-288072-42sx52tn 58 11 considered consider VBN cord-288072-42sx52tn 58 12 significant significant JJ cord-288072-42sx52tn 58 13 . . . cord-288072-42sx52tn 59 1 Approximately approximately RB cord-288072-42sx52tn 59 2 40 40 CD cord-288072-42sx52tn 59 3 % % NN cord-288072-42sx52tn 59 4 of of IN cord-288072-42sx52tn 59 5 serum serum NN cord-288072-42sx52tn 59 6 pairs pair NNS cord-288072-42sx52tn 59 7 demonstrating demonstrate VBG cord-288072-42sx52tn 59 8 a a DT cord-288072-42sx52tn 59 9 significant significant JJ cord-288072-42sx52tn 59 10 rise rise NN cord-288072-42sx52tn 59 11 in in IN cord-288072-42sx52tn 59 12 antibody antibody NN cord-288072-42sx52tn 59 13 titer titer NN cord-288072-42sx52tn 59 14 by by IN cord-288072-42sx52tn 59 15 CF CF NNP cord-288072-42sx52tn 59 16 and and CC cord-288072-42sx52tn 59 17 HAl HAl NNPS cord-288072-42sx52tn 59 18 were be VBD cord-288072-42sx52tn 59 19 also also RB cord-288072-42sx52tn 59 20 tested test VBN cord-288072-42sx52tn 59 21 by by IN cord-288072-42sx52tn 59 22 neutralization neutralization NN cord-288072-42sx52tn 59 23 [ [ -LRB- cord-288072-42sx52tn 59 24 9 9 CD cord-288072-42sx52tn 59 25 ] ] -RRB- cord-288072-42sx52tn 59 26 . . . cord-288072-42sx52tn 60 1 The the DT cord-288072-42sx52tn 60 2 neutralization neutralization NN cord-288072-42sx52tn 60 3 tests test NNS cord-288072-42sx52tn 60 4 were be VBD cord-288072-42sx52tn 60 5 performed perform VBN cord-288072-42sx52tn 60 6 in in IN cord-288072-42sx52tn 60 7 cultures culture NNS cord-288072-42sx52tn 60 8 of of IN cord-288072-42sx52tn 60 9 BS BS NNP cord-288072-42sx52tn 60 10 - - HYPH cord-288072-42sx52tn 60 11 C-1 C-1 NNP cord-288072-42sx52tn 60 12 cells cell NNS cord-288072-42sx52tn 60 13 . . . cord-288072-42sx52tn 61 1 Cells cell NNS cord-288072-42sx52tn 61 2 were be VBD cord-288072-42sx52tn 61 3 grown grow VBN cord-288072-42sx52tn 61 4 in in IN cord-288072-42sx52tn 61 5 Eagle Eagle NNP cord-288072-42sx52tn 61 6 's 's POS cord-288072-42sx52tn 61 7 minimal minimal JJ cord-288072-42sx52tn 61 8 essential essential JJ cord-288072-42sx52tn 61 9 medium medium NN cord-288072-42sx52tn 61 10 ( ( -LRB- cord-288072-42sx52tn 61 11 MEM MEM NNP cord-288072-42sx52tn 61 12 ) ) -RRB- cord-288072-42sx52tn 61 13 made make VBN cord-288072-42sx52tn 61 14 in in IN cord-288072-42sx52tn 61 15 Hanks Hanks NNP cord-288072-42sx52tn 61 16 ' ' POS cord-288072-42sx52tn 61 17 salts salt NNS cord-288072-42sx52tn 61 18 with with IN cord-288072-42sx52tn 61 19 10 10 CD cord-288072-42sx52tn 61 20 % % NN cord-288072-42sx52tn 61 21 fetal fetal JJ cord-288072-42sx52tn 61 22 bovine bovine JJ cord-288072-42sx52tn 61 23 serum serum NN cord-288072-42sx52tn 61 24 . . . cord-288072-42sx52tn 62 1 Before before IN cord-288072-42sx52tn 62 2 use use NN cord-288072-42sx52tn 62 3 , , , cord-288072-42sx52tn 62 4 the the DT cord-288072-42sx52tn 62 5 cultures culture NNS cord-288072-42sx52tn 62 6 were be VBD cord-288072-42sx52tn 62 7 washed wash VBN cord-288072-42sx52tn 62 8 three three CD cord-288072-42sx52tn 62 9 times time NNS cord-288072-42sx52tn 62 10 with with IN cord-288072-42sx52tn 62 11 balanced balanced JJ cord-288072-42sx52tn 62 12 salt salt NN cord-288072-42sx52tn 62 13 solution solution NN cord-288072-42sx52tn 62 14 , , , cord-288072-42sx52tn 62 15 and and CC cord-288072-42sx52tn 62 16 they -PRON- PRP cord-288072-42sx52tn 62 17 were be VBD cord-288072-42sx52tn 62 18 maintained maintain VBN cord-288072-42sx52tn 62 19 on on IN cord-288072-42sx52tn 62 20 serum serum NN cord-288072-42sx52tn 62 21 - - HYPH cord-288072-42sx52tn 62 22 free free JJ cord-288072-42sx52tn 62 23 MEM mem NN cord-288072-42sx52tn 62 24 in in IN cord-288072-42sx52tn 62 25 Earle Earle NNP cord-288072-42sx52tn 62 26 's 's POS cord-288072-42sx52tn 62 27 salts salt NNS cord-288072-42sx52tn 62 28 . . . cord-288072-42sx52tn 63 1 Virus virus NN cord-288072-42sx52tn 63 2 was be VBD cord-288072-42sx52tn 63 3 used use VBN cord-288072-42sx52tn 63 4 at at IN cord-288072-42sx52tn 63 5 a a DT cord-288072-42sx52tn 63 6 dose dose NN cord-288072-42sx52tn 63 7 of of IN cord-288072-42sx52tn 63 8 100 100 CD cord-288072-42sx52tn 63 9 - - SYM cord-288072-42sx52tn 63 10 320 320 CD cord-288072-42sx52tn 63 11 TCID50/0.1 TCID50/0.1 NNP cord-288072-42sx52tn 63 12 ml ml XX cord-288072-42sx52tn 63 13 . . . cord-288072-42sx52tn 64 1 After after IN cord-288072-42sx52tn 64 2 inactivation inactivation NN cord-288072-42sx52tn 64 3 at at IN cord-288072-42sx52tn 64 4 56 56 CD cord-288072-42sx52tn 64 5 C c NN cord-288072-42sx52tn 64 6 for for IN cord-288072-42sx52tn 64 7 30 30 CD cord-288072-42sx52tn 64 8 min min NN cord-288072-42sx52tn 64 9 the the DT cord-288072-42sx52tn 64 10 sera sera NNP cord-288072-42sx52tn 64 11 were be VBD cord-288072-42sx52tn 64 12 serially serially RB cord-288072-42sx52tn 64 13 diluted dilute VBN cord-288072-42sx52tn 64 14 . . . cord-288072-42sx52tn 65 1 To to IN cord-288072-42sx52tn 65 2 0.3 0.3 CD cord-288072-42sx52tn 65 3 ml ml NNS cord-288072-42sx52tn 65 4 of of IN cord-288072-42sx52tn 65 5 diluted diluted JJ cord-288072-42sx52tn 65 6 sera sera NNP cord-288072-42sx52tn 65 7 , , , cord-288072-42sx52tn 65 8 0.3 0.3 CD cord-288072-42sx52tn 65 9 ml ml XX cord-288072-42sx52tn 65 10 of of IN cord-288072-42sx52tn 65 11 the the DT cord-288072-42sx52tn 65 12 appropriate appropriate JJ cord-288072-42sx52tn 65 13 dilution dilution NN cord-288072-42sx52tn 65 14 of of IN cord-288072-42sx52tn 65 15 virus virus NN cord-288072-42sx52tn 65 16 was be VBD cord-288072-42sx52tn 65 17 added add VBN cord-288072-42sx52tn 65 18 , , , cord-288072-42sx52tn 65 19 and and CC cord-288072-42sx52tn 65 20 the the DT cord-288072-42sx52tn 65 21 mixture mixture NN cord-288072-42sx52tn 65 22 was be VBD cord-288072-42sx52tn 65 23 incubated incubate VBN cord-288072-42sx52tn 65 24 at at IN cord-288072-42sx52tn 65 25 24 24 CD cord-288072-42sx52tn 65 26 C c NN cord-288072-42sx52tn 65 27 for for IN cord-288072-42sx52tn 65 28 1 1 CD cord-288072-42sx52tn 65 29 hr hr NN cord-288072-42sx52tn 65 30 . . . cord-288072-42sx52tn 66 1 Thereafter thereafter IN cord-288072-42sx52tn 66 2 0.2 0.2 CD cord-288072-42sx52tn 66 3 ml ml NNS cord-288072-42sx52tn 66 4 of of IN cord-288072-42sx52tn 66 5 each each DT cord-288072-42sx52tn 66 6 mixture mixture NN cord-288072-42sx52tn 66 7 of of IN cord-288072-42sx52tn 66 8 serum serum NN cord-288072-42sx52tn 66 9 and and CC cord-288072-42sx52tn 66 10 virus virus NN cord-288072-42sx52tn 66 11 was be VBD cord-288072-42sx52tn 66 12 inoculated inoculate VBN cord-288072-42sx52tn 66 13 into into IN cord-288072-42sx52tn 66 14 each each DT cord-288072-42sx52tn 66 15 of of IN cord-288072-42sx52tn 66 16 two two CD cord-288072-42sx52tn 66 17 cell cell NN cord-288072-42sx52tn 66 18 - - HYPH cord-288072-42sx52tn 66 19 culture culture NN cord-288072-42sx52tn 66 20 tubes tube NNS cord-288072-42sx52tn 66 21 . . . cord-288072-42sx52tn 67 1 The the DT cord-288072-42sx52tn 67 2 tubes tube NNS cord-288072-42sx52tn 67 3 were be VBD cord-288072-42sx52tn 67 4 placed place VBN cord-288072-42sx52tn 67 5 in in IN cord-288072-42sx52tn 67 6 a a DT cord-288072-42sx52tn 67 7 roller roller NN cord-288072-42sx52tn 67 8 drum drum NN cord-288072-42sx52tn 67 9 and and CC cord-288072-42sx52tn 67 10 incubated incubate VBD cord-288072-42sx52tn 67 11 at at IN cord-288072-42sx52tn 67 12 33 33 CD cord-288072-42sx52tn 67 13 C. C. NNP cord-288072-42sx52tn 67 14 After after IN cord-288072-42sx52tn 67 15 four four CD cord-288072-42sx52tn 67 16 days day NNS cord-288072-42sx52tn 67 17 , , , cord-288072-42sx52tn 67 18 rat rat NN cord-288072-42sx52tn 67 19 erythrocytes erythrocyte NNS cord-288072-42sx52tn 67 20 were be VBD cord-288072-42sx52tn 67 21 washed wash VBN cord-288072-42sx52tn 67 22 three three CD cord-288072-42sx52tn 67 23 times time NNS cord-288072-42sx52tn 67 24 , , , cord-288072-42sx52tn 67 25 and and CC cord-288072-42sx52tn 67 26 0.2 0.2 CD cord-288072-42sx52tn 67 27 ml ml NNS cord-288072-42sx52tn 67 28 of of IN cord-288072-42sx52tn 67 29 a a DT cord-288072-42sx52tn 67 30 0.4 0.4 CD cord-288072-42sx52tn 67 31 % % NN cord-288072-42sx52tn 67 32 solution solution NN cord-288072-42sx52tn 67 33 was be VBD cord-288072-42sx52tn 67 34 added add VBN cord-288072-42sx52tn 67 35 to to IN cord-288072-42sx52tn 67 36 each each DT cord-288072-42sx52tn 67 37 cell cell NN cord-288072-42sx52tn 67 38 - - HYPH cord-288072-42sx52tn 67 39 culture culture NN cord-288072-42sx52tn 67 40 tube tube NN cord-288072-42sx52tn 67 41 . . . cord-288072-42sx52tn 68 1 Tubes tube NNS cord-288072-42sx52tn 68 2 were be VBD cord-288072-42sx52tn 68 3 examined examine VBN cord-288072-42sx52tn 68 4 microscopically microscopically RB cord-288072-42sx52tn 68 5 after after IN cord-288072-42sx52tn 68 6 45 45 CD cord-288072-42sx52tn 68 7 min min NN cord-288072-42sx52tn 68 8 at at IN cord-288072-42sx52tn 68 9 24 24 CD cord-288072-42sx52tn 68 10 C C NNP cord-288072-42sx52tn 68 11 , , , cord-288072-42sx52tn 68 12 and and CC cord-288072-42sx52tn 68 13 end end NN cord-288072-42sx52tn 68 14 points point NNS cord-288072-42sx52tn 68 15 were be VBD cord-288072-42sx52tn 68 16 determined determine VBN cord-288072-42sx52tn 68 17 based base VBN cord-288072-42sx52tn 68 18 on on IN cord-288072-42sx52tn 68 19 the the DT cord-288072-42sx52tn 68 20 presence presence NN cord-288072-42sx52tn 68 21 of of IN cord-288072-42sx52tn 68 22 virus virus NN cord-288072-42sx52tn 68 23 - - HYPH cord-288072-42sx52tn 68 24 specific specific JJ cord-288072-42sx52tn 68 25 hemadsorption hemadsorption NN cord-288072-42sx52tn 68 26 . . . cord-288072-42sx52tn 69 1 All all DT cord-288072-42sx52tn 69 2 specimens specimen NNS cord-288072-42sx52tn 69 3 of of IN cord-288072-42sx52tn 69 4 serum serum NN cord-288072-42sx52tn 69 5 collected collect VBN cord-288072-42sx52tn 69 6 from from IN cord-288072-42sx52tn 69 7 members member NNS cord-288072-42sx52tn 69 8 of of IN cord-288072-42sx52tn 69 9 269 269 CD cord-288072-42sx52tn 69 10 families family NNS cord-288072-42sx52tn 69 11 were be VBD cord-288072-42sx52tn 69 12 studied study VBN cord-288072-42sx52tn 69 13 by by IN cord-288072-42sx52tn 69 14 CF CF NNP cord-288072-42sx52tn 69 15 and and CC cord-288072-42sx52tn 69 16 HAl HAl NNPS cord-288072-42sx52tn 69 17 for for IN cord-288072-42sx52tn 69 18 rise rise NN cord-288072-42sx52tn 69 19 in in IN cord-288072-42sx52tn 69 20 titer titer NN cord-288072-42sx52tn 69 21 of of IN cord-288072-42sx52tn 69 22 antibody antibody NN cord-288072-42sx52tn 69 23 to to TO cord-288072-42sx52tn 69 24 coronavirus coronavirus NN cord-288072-42sx52tn 69 25 OC43 OC43 NNP cord-288072-42sx52tn 69 26 . . . cord-288072-42sx52tn 70 1 These these DT cord-288072-42sx52tn 70 2 specimens specimen NNS cord-288072-42sx52tn 70 3 had have VBD cord-288072-42sx52tn 70 4 been be VBN cord-288072-42sx52tn 70 5 collected collect VBN cord-288072-42sx52tn 70 6 from from IN cord-288072-42sx52tn 70 7 November November NNP cord-288072-42sx52tn 70 8 1965 1965 CD cord-288072-42sx52tn 70 9 to to IN cord-288072-42sx52tn 70 10 June June NNP cord-288072-42sx52tn 70 11 1969 1969 CD cord-288072-42sx52tn 70 12 . . . cord-288072-42sx52tn 71 1 In in IN cord-288072-42sx52tn 71 2 nearly nearly RB cord-288072-42sx52tn 71 3 all all DT cord-288072-42sx52tn 71 4 cases case NNS cord-288072-42sx52tn 71 5 , , , cord-288072-42sx52tn 71 6 three three CD cord-288072-42sx52tn 71 7 specimens specimen NNS cord-288072-42sx52tn 71 8 were be VBD cord-288072-42sx52tn 71 9 obtained obtain VBN cord-288072-42sx52tn 71 10 from from IN cord-288072-42sx52tn 71 11 each each DT cord-288072-42sx52tn 71 12 individual individual NN cord-288072-42sx52tn 71 13 during during IN cord-288072-42sx52tn 71 14 each each DT cord-288072-42sx52tn 71 15 period period NN cord-288072-42sx52tn 71 16 of of IN cord-288072-42sx52tn 71 17 surveillance surveillance NN cord-288072-42sx52tn 71 18 . . . cord-288072-42sx52tn 72 1 To to TO cord-288072-42sx52tn 72 2 determine determine VB cord-288072-42sx52tn 72 3 the the DT cord-288072-42sx52tn 72 4 temporal temporal JJ cord-288072-42sx52tn 72 5 occurrence occurrence NN cord-288072-42sx52tn 72 6 of of IN cord-288072-42sx52tn 72 7 infection infection NN cord-288072-42sx52tn 72 8 with with IN cord-288072-42sx52tn 72 9 OC43related oc43related JJ cord-288072-42sx52tn 72 10 viruses virus NNS cord-288072-42sx52tn 72 11 , , , cord-288072-42sx52tn 72 12 the the DT cord-288072-42sx52tn 72 13 three three CD cord-288072-42sx52tn 72 14 specimens specimen NNS cord-288072-42sx52tn 72 15 collected collect VBN cord-288072-42sx52tn 72 16 from from IN cord-288072-42sx52tn 72 17 each each DT cord-288072-42sx52tn 72 18 person person NN cord-288072-42sx52tn 72 19 were be VBD cord-288072-42sx52tn 72 20 divided divide VBN cord-288072-42sx52tn 72 21 into into IN cord-288072-42sx52tn 72 22 two two CD cord-288072-42sx52tn 72 23 component component NN cord-288072-42sx52tn 72 24 pairs pair NNS cord-288072-42sx52tn 72 25 , , , cord-288072-42sx52tn 72 26 each each DT cord-288072-42sx52tn 72 27 spanning span VBG cord-288072-42sx52tn 72 28 a a DT cord-288072-42sx52tn 72 29 six six CD cord-288072-42sx52tn 72 30 - - HYPH cord-288072-42sx52tn 72 31 month month NN cord-288072-42sx52tn 72 32 period period NN cord-288072-42sx52tn 72 33 . . . cord-288072-42sx52tn 73 1 The the DT cord-288072-42sx52tn 73 2 time time NN cord-288072-42sx52tn 73 3 of of IN cord-288072-42sx52tn 73 4 each each DT cord-288072-42sx52tn 73 5 pair pair NN cord-288072-42sx52tn 73 6 was be VBD cord-288072-42sx52tn 73 7 identified identify VBN cord-288072-42sx52tn 73 8 by by IN cord-288072-42sx52tn 73 9 the the DT cord-288072-42sx52tn 73 10 month month NN cord-288072-42sx52tn 73 11 of of IN cord-288072-42sx52tn 73 12 collection collection NN cord-288072-42sx52tn 73 13 of of IN cord-288072-42sx52tn 73 14 the the DT cord-288072-42sx52tn 73 15 second second JJ cord-288072-42sx52tn 73 16 serum serum NN cord-288072-42sx52tn 73 17 of of IN cord-288072-42sx52tn 73 18 that that DT cord-288072-42sx52tn 73 19 pair pair NN cord-288072-42sx52tn 73 20 . . . cord-288072-42sx52tn 74 1 Results result NNS cord-288072-42sx52tn 74 2 of of IN cord-288072-42sx52tn 74 3 the the DT cord-288072-42sx52tn 74 4 serologic serologic JJ cord-288072-42sx52tn 74 5 tests test NNS cord-288072-42sx52tn 74 6 are be VBP cord-288072-42sx52tn 74 7 shown show VBN cord-288072-42sx52tn 74 8 in in IN cord-288072-42sx52tn 74 9 figure figure NN cord-288072-42sx52tn 74 10 1 1 CD cord-288072-42sx52tn 74 11 . . . cord-288072-42sx52tn 75 1 Rises rise NNS cord-288072-42sx52tn 75 2 in in IN cord-288072-42sx52tn 75 3 CF cf NN cord-288072-42sx52tn 75 4 and and CC cord-288072-42sx52tn 75 5 HAl hal JJ cord-288072-42sx52tn 75 6 titers titer NNS cord-288072-42sx52tn 75 7 frequently frequently RB cord-288072-42sx52tn 75 8 were be VBD cord-288072-42sx52tn 75 9 independent independent JJ cord-288072-42sx52tn 75 10 of of IN cord-288072-42sx52tn 75 11 each each DT cord-288072-42sx52tn 75 12 other other JJ cord-288072-42sx52tn 75 13 . . . cord-288072-42sx52tn 76 1 Therefore therefore RB cord-288072-42sx52tn 76 2 , , , cord-288072-42sx52tn 76 3 each each DT cord-288072-42sx52tn 76 4 rise rise NN cord-288072-42sx52tn 76 5 was be VBD cord-288072-42sx52tn 76 6 counted count VBN cord-288072-42sx52tn 76 7 without without IN cord-288072-42sx52tn 76 8 regard regard NN cord-288072-42sx52tn 76 9 to to IN cord-288072-42sx52tn 76 10 the the DT cord-288072-42sx52tn 76 11 presence presence NN cord-288072-42sx52tn 76 12 or or CC cord-288072-42sx52tn 76 13 absence absence NN cord-288072-42sx52tn 76 14 of of IN cord-288072-42sx52tn 76 15 the the DT cord-288072-42sx52tn 76 16 other other JJ cord-288072-42sx52tn 76 17 and and CC cord-288072-42sx52tn 76 18 is be VBZ cord-288072-42sx52tn 76 19 indicated indicate VBN cord-288072-42sx52tn 76 20 as as IN cord-288072-42sx52tn 76 21 a a DT cord-288072-42sx52tn 76 22 separate separate JJ cord-288072-42sx52tn 76 23 curve curve NN cord-288072-42sx52tn 76 24 in in IN cord-288072-42sx52tn 76 25 the the DT cord-288072-42sx52tn 76 26 figure figure NN cord-288072-42sx52tn 76 27 . . . cord-288072-42sx52tn 77 1 Bars bar NNS cord-288072-42sx52tn 77 2 indicate indicate VBP cord-288072-42sx52tn 77 3 the the DT cord-288072-42sx52tn 77 4 percentage percentage NN cord-288072-42sx52tn 77 5 of of IN cord-288072-42sx52tn 77 6 total total JJ cord-288072-42sx52tn 77 7 specimens specimen NNS cord-288072-42sx52tn 77 8 tested test VBN cord-288072-42sx52tn 77 9 in in IN cord-288072-42sx52tn 77 10 which which WDT cord-288072-42sx52tn 77 11 the the DT cord-288072-42sx52tn 77 12 rises rise NNS cord-288072-42sx52tn 77 13 in in IN cord-288072-42sx52tn 77 14 titer titer NN cord-288072-42sx52tn 77 15 by by IN cord-288072-42sx52tn 77 16 CF CF NNP cord-288072-42sx52tn 77 17 and and CC cord-288072-42sx52tn 77 18 HAl HAl NNPS cord-288072-42sx52tn 77 19 occurred occur VBD cord-288072-42sx52tn 77 20 together together RB cord-288072-42sx52tn 77 21 . . . cord-288072-42sx52tn 78 1 It -PRON- PRP cord-288072-42sx52tn 78 2 has have VBZ cord-288072-42sx52tn 78 3 been be VBN cord-288072-42sx52tn 78 4 reported report VBN cord-288072-42sx52tn 78 5 that that IN cord-288072-42sx52tn 78 6 the the DT cord-288072-42sx52tn 78 7 principal principal JJ cord-288072-42sx52tn 78 8 periods period NNS cord-288072-42sx52tn 78 9 of of IN cord-288072-42sx52tn 78 10 transmission transmission NN cord-288072-42sx52tn 78 11 of of IN cord-288072-42sx52tn 78 12 coronavirus coronavirus NN cord-288072-42sx52tn 78 13 are be VBP cord-288072-42sx52tn 78 14 in in IN cord-288072-42sx52tn 78 15 the the DT cord-288072-42sx52tn 78 16 winter winter NN cord-288072-42sx52tn 78 17 and and CC cord-288072-42sx52tn 78 18 early early JJ cord-288072-42sx52tn 78 19 spring spring NN cord-288072-42sx52tn 78 20 [ [ -LRB- cord-288072-42sx52tn 78 21 2 2 CD cord-288072-42sx52tn 78 22 , , , cord-288072-42sx52tn 78 23 3 3 CD cord-288072-42sx52tn 78 24 ] ] -RRB- cord-288072-42sx52tn 78 25 . . . cord-288072-42sx52tn 79 1 This this DT cord-288072-42sx52tn 79 2 pattern pattern NN cord-288072-42sx52tn 79 3 could could MD cord-288072-42sx52tn 79 4 be be VB cord-288072-42sx52tn 79 5 seen see VBN cord-288072-42sx52tn 79 6 when when WRB cord-288072-42sx52tn 79 7 the the DT cord-288072-42sx52tn 79 8 CF CF NNP cord-288072-42sx52tn 79 9 and and CC cord-288072-42sx52tn 79 10 HAl hal JJ cord-288072-42sx52tn 79 11 curves curve NNS cord-288072-42sx52tn 79 12 for for IN cord-288072-42sx52tn 79 13 OC43 OC43 NNP cord-288072-42sx52tn 79 14 were be VBD cord-288072-42sx52tn 79 15 examined examine VBN cord-288072-42sx52tn 79 16 . . . cord-288072-42sx52tn 80 1 Frequent frequent JJ cord-288072-42sx52tn 80 2 infections infection NNS cord-288072-42sx52tn 80 3 were be VBD cord-288072-42sx52tn 80 4 detected detect VBN cord-288072-42sx52tn 80 5 by by IN cord-288072-42sx52tn 80 6 CF CF NNP cord-288072-42sx52tn 80 7 and and CC cord-288072-42sx52tn 80 8 HAl HAl NNPS cord-288072-42sx52tn 80 9 in in IN cord-288072-42sx52tn 80 10 sera sera NNP cord-288072-42sx52tn 80 11 collected collect VBN cord-288072-42sx52tn 80 12 during during IN cord-288072-42sx52tn 80 13 the the DT cord-288072-42sx52tn 80 14 six- six- NN cord-288072-42sx52tn 80 15 as as IN cord-288072-42sx52tn 80 16 one one CD cord-288072-42sx52tn 80 17 means mean NNS cord-288072-42sx52tn 80 18 of of IN cord-288072-42sx52tn 80 19 exploring explore VBG cord-288072-42sx52tn 80 20 the the DT cord-288072-42sx52tn 80 21 divergence divergence NN cord-288072-42sx52tn 80 22 in in IN cord-288072-42sx52tn 80 23 serologic serologic JJ cord-288072-42sx52tn 80 24 results result NNS cord-288072-42sx52tn 80 25 . . . cord-288072-42sx52tn 81 1 Results result NNS cord-288072-42sx52tn 81 2 are be VBP cord-288072-42sx52tn 81 3 given give VBN cord-288072-42sx52tn 81 4 in in IN cord-288072-42sx52tn 81 5 table table NN cord-288072-42sx52tn 81 6 1 1 CD cord-288072-42sx52tn 81 7 . . . cord-288072-42sx52tn 82 1 The the DT cord-288072-42sx52tn 82 2 overall overall JJ cord-288072-42sx52tn 82 3 rate rate NN cord-288072-42sx52tn 82 4 of of IN cord-288072-42sx52tn 82 5 infection infection NN cord-288072-42sx52tn 82 6 for for IN cord-288072-42sx52tn 82 7 each each DT cord-288072-42sx52tn 82 8 age age NN cord-288072-42sx52tn 82 9 group group NN cord-288072-42sx52tn 82 10 was be VBD cord-288072-42sx52tn 82 11 calculated calculate VBN cord-288072-42sx52tn 82 12 by by IN cord-288072-42sx52tn 82 13 determining determine VBG cord-288072-42sx52tn 82 14 the the DT cord-288072-42sx52tn 82 15 total total JJ cord-288072-42sx52tn 82 16 number number NN cord-288072-42sx52tn 82 17 of of IN cord-288072-42sx52tn 82 18 individuals individual NNS cord-288072-42sx52tn 82 19 who who WP cord-288072-42sx52tn 82 20 showed show VBD cord-288072-42sx52tn 82 21 a a DT cord-288072-42sx52tn 82 22 rise rise NN cord-288072-42sx52tn 82 23 in in IN cord-288072-42sx52tn 82 24 antibody antibody NN cord-288072-42sx52tn 82 25 titer titer NN cord-288072-42sx52tn 82 26 by by IN cord-288072-42sx52tn 82 27 CF CF NNP cord-288072-42sx52tn 82 28 and/or and/or CC cord-288072-42sx52tn 82 29 HAl HAl NNP cord-288072-42sx52tn 82 30 . . . cord-288072-42sx52tn 83 1 The the DT cord-288072-42sx52tn 83 2 proportion proportion NN cord-288072-42sx52tn 83 3 of of IN cord-288072-42sx52tn 83 4 these these DT cord-288072-42sx52tn 83 5 infected infect VBN cord-288072-42sx52tn 83 6 individuals individual NNS cord-288072-42sx52tn 83 7 who who WP cord-288072-42sx52tn 83 8 had have VBD cord-288072-42sx52tn 83 9 a a DT cord-288072-42sx52tn 83 10 rise rise NN cord-288072-42sx52tn 83 11 in in IN cord-288072-42sx52tn 83 12 CF CF NNP cord-288072-42sx52tn 83 13 antibody antibody NN cord-288072-42sx52tn 83 14 was be VBD cord-288072-42sx52tn 83 15 then then RB cord-288072-42sx52tn 83 16 calculated calculate VBN cord-288072-42sx52tn 83 17 as as IN cord-288072-42sx52tn 83 18 was be VBD cord-288072-42sx52tn 83 19 the the DT cord-288072-42sx52tn 83 20 proportion proportion NN cord-288072-42sx52tn 83 21 of of IN cord-288072-42sx52tn 83 22 infected infected JJ cord-288072-42sx52tn 83 23 individuals individual NNS cord-288072-42sx52tn 83 24 with with IN cord-288072-42sx52tn 83 25 a a DT cord-288072-42sx52tn 83 26 rise rise NN cord-288072-42sx52tn 83 27 in in IN cord-288072-42sx52tn 83 28 HAl hal JJ cord-288072-42sx52tn 83 29 antibody antibody NN cord-288072-42sx52tn 83 30 . . . cord-288072-42sx52tn 84 1 Since since IN cord-288072-42sx52tn 84 2 the the DT cord-288072-42sx52tn 84 3 intent intent NN cord-288072-42sx52tn 84 4 was be VBD cord-288072-42sx52tn 84 5 determination determination NN cord-288072-42sx52tn 84 6 of of IN cord-288072-42sx52tn 84 7 the the DT cord-288072-42sx52tn 84 8 relative relative JJ cord-288072-42sx52tn 84 9 frequency frequency NN cord-288072-42sx52tn 84 10 of of IN cord-288072-42sx52tn 84 11 rise rise NN cord-288072-42sx52tn 84 12 in in IN cord-288072-42sx52tn 84 13 titer titer NN cord-288072-42sx52tn 84 14 detected detect VBN cord-288072-42sx52tn 84 15 by by IN cord-288072-42sx52tn 84 16 each each DT cord-288072-42sx52tn 84 17 test test NN cord-288072-42sx52tn 84 18 , , , cord-288072-42sx52tn 84 19 persons person NNS cord-288072-42sx52tn 84 20 with with IN cord-288072-42sx52tn 84 21 increases increase NNS cord-288072-42sx52tn 84 22 in in IN cord-288072-42sx52tn 84 23 both both CC cord-288072-42sx52tn 84 24 CF CF NNP cord-288072-42sx52tn 84 25 and and CC cord-288072-42sx52tn 84 26 HAl hal JJ cord-288072-42sx52tn 84 27 titer titer NN cord-288072-42sx52tn 84 28 were be VBD cord-288072-42sx52tn 84 29 counted count VBN cord-288072-42sx52tn 84 30 in in IN cord-288072-42sx52tn 84 31 both both DT cord-288072-42sx52tn 84 32 categories category NNS cord-288072-42sx52tn 84 33 . . . cord-288072-42sx52tn 85 1 As as IN cord-288072-42sx52tn 85 2 shown show VBN cord-288072-42sx52tn 85 3 in in IN cord-288072-42sx52tn 85 4 table table NN cord-288072-42sx52tn 85 5 1 1 CD cord-288072-42sx52tn 85 6 , , , cord-288072-42sx52tn 85 7 age age NN cord-288072-42sx52tn 85 8 did do VBD cord-288072-42sx52tn 85 9 not not RB cord-288072-42sx52tn 85 10 appear appear VB cord-288072-42sx52tn 85 11 to to TO cord-288072-42sx52tn 85 12 be be VB cord-288072-42sx52tn 85 13 a a DT cord-288072-42sx52tn 85 14 factor factor NN cord-288072-42sx52tn 85 15 in in IN cord-288072-42sx52tn 85 16 determining determine VBG cord-288072-42sx52tn 85 17 the the DT cord-288072-42sx52tn 85 18 type type NN cord-288072-42sx52tn 85 19 of of IN cord-288072-42sx52tn 85 20 response response NN cord-288072-42sx52tn 85 21 . . . cord-288072-42sx52tn 86 1 At at IN cord-288072-42sx52tn 86 2 all all DT cord-288072-42sx52tn 86 3 ages age NNS cord-288072-42sx52tn 86 4 below below IN cord-288072-42sx52tn 86 5 40 40 CD cord-288072-42sx52tn 86 6 years year NNS cord-288072-42sx52tn 86 7 , , , cord-288072-42sx52tn 86 8 rises rise VBZ cord-288072-42sx52tn 86 9 in in IN cord-288072-42sx52tn 86 10 titer titer NN cord-288072-42sx52tn 86 11 were be VBD cord-288072-42sx52tn 86 12 more more RBR cord-288072-42sx52tn 86 13 frequently frequently RB cord-288072-42sx52tn 86 14 detected detect VBN cord-288072-42sx52tn 86 15 by by IN cord-288072-42sx52tn 86 16 HAl HAl NNS cord-288072-42sx52tn 86 17 than than IN cord-288072-42sx52tn 86 18 by by IN cord-288072-42sx52tn 86 19 CF CF NNP cord-288072-42sx52tn 86 20 , , , cord-288072-42sx52tn 86 21 but but CC cord-288072-42sx52tn 86 22 the the DT cord-288072-42sx52tn 86 23 difference difference NN cord-288072-42sx52tn 86 24 was be VBD cord-288072-42sx52tn 86 25 often often RB cord-288072-42sx52tn 86 26 not not RB cord-288072-42sx52tn 86 27 great great JJ cord-288072-42sx52tn 86 28 . . . cord-288072-42sx52tn 87 1 Only only RB cord-288072-42sx52tn 87 2 among among IN cord-288072-42sx52tn 87 3 individuals individual NNS cord-288072-42sx52tn 87 4 40 40 CD cord-288072-42sx52tn 87 5 years year NNS cord-288072-42sx52tn 87 6 and and CC cord-288072-42sx52tn 87 7 older old JJR cord-288072-42sx52tn 87 8 was be VBD cord-288072-42sx52tn 87 9 this this DT cord-288072-42sx52tn 87 10 pattern pattern NN cord-288072-42sx52tn 87 11 reversed reverse VBN cord-288072-42sx52tn 87 12 slightly slightly RB cord-288072-42sx52tn 87 13 . . . cord-288072-42sx52tn 88 1 The the DT cord-288072-42sx52tn 88 2 total total JJ cord-288072-42sx52tn 88 3 rates rate NNS cord-288072-42sx52tn 88 4 of of IN cord-288072-42sx52tn 88 5 infection infection NN cord-288072-42sx52tn 88 6 ( ( -LRB- cord-288072-42sx52tn 88 7 table table NN cord-288072-42sx52tn 88 8 1 1 CD cord-288072-42sx52tn 88 9 ) ) -RRB- cord-288072-42sx52tn 88 10 fell fall VBD cord-288072-42sx52tn 88 11 gradually gradually RB cord-288072-42sx52tn 88 12 as as IN cord-288072-42sx52tn 88 13 age age NN cord-288072-42sx52tn 88 14 increased increase VBD cord-288072-42sx52tn 88 15 , , , cord-288072-42sx52tn 88 16 but but CC cord-288072-42sx52tn 88 17 not not RB cord-288072-42sx52tn 88 18 as as RB cord-288072-42sx52tn 88 19 precipitously precipitously RB cord-288072-42sx52tn 88 20 as as IN cord-288072-42sx52tn 88 21 with with IN cord-288072-42sx52tn 88 22 other other JJ cord-288072-42sx52tn 88 23 respiratory respiratory JJ cord-288072-42sx52tn 88 24 pathogens pathogen NNS cord-288072-42sx52tn 88 25 ' ' '' cord-288072-42sx52tn 88 26 [ [ -LRB- cord-288072-42sx52tn 88 27 10 10 CD cord-288072-42sx52tn 88 28 , , , cord-288072-42sx52tn 88 29 13 13 CD cord-288072-42sx52tn 88 30 ] ] -RRB- cord-288072-42sx52tn 88 31 . . . cord-288072-42sx52tn 89 1 A a DT cord-288072-42sx52tn 89 2 high high JJ cord-288072-42sx52tn 89 3 annual annual JJ cord-288072-42sx52tn 89 4 rate rate NN cord-288072-42sx52tn 89 5 of of IN cord-288072-42sx52tn 89 6 infection infection NN cord-288072-42sx52tn 89 7 was be VBD cord-288072-42sx52tn 89 8 observed observe VBN cord-288072-42sx52tn 89 9 among among IN cord-288072-42sx52tn 89 10 all all DT cord-288072-42sx52tn 89 11 adults adult NNS cord-288072-42sx52tn 89 12 studied study VBD cord-288072-42sx52tn 89 13 . . . cord-288072-42sx52tn 90 1 Study study NN cord-288072-42sx52tn 90 2 of of IN cord-288072-42sx52tn 90 3 specificity specificity NN cord-288072-42sx52tn 90 4 of of IN cord-288072-42sx52tn 90 5 antibody antibody NN cord-288072-42sx52tn 90 6 response response NN cord-288072-42sx52tn 90 7 . . . cord-288072-42sx52tn 91 1 Agreement agreement NN cord-288072-42sx52tn 91 2 between between IN cord-288072-42sx52tn 91 3 the the DT cord-288072-42sx52tn 91 4 HAl hal JJ cord-288072-42sx52tn 91 5 and and CC cord-288072-42sx52tn 91 6 CF CF NNP cord-288072-42sx52tn 91 7 tests test NNS cord-288072-42sx52tn 91 8 was be VBD cord-288072-42sx52tn 91 9 better well JJR cord-288072-42sx52tn 91 10 in in IN cord-288072-42sx52tn 91 11 the the DT cord-288072-42sx52tn 91 12 first first JJ cord-288072-42sx52tn 91 13 part part NN cord-288072-42sx52tn 91 14 of of IN cord-288072-42sx52tn 91 15 1966 1966 CD cord-288072-42sx52tn 91 16 and and CC cord-288072-42sx52tn 91 17 in in IN cord-288072-42sx52tn 91 18 early early JJ cord-288072-42sx52tn 91 19 1969 1969 CD cord-288072-42sx52tn 91 20 than than IN cord-288072-42sx52tn 91 21 at at IN cord-288072-42sx52tn 91 22 other other JJ cord-288072-42sx52tn 91 23 times time NNS cord-288072-42sx52tn 91 24 , , , cord-288072-42sx52tn 91 25 including include VBG cord-288072-42sx52tn 91 26 the the DT cord-288072-42sx52tn 91 27 peak peak NN cord-288072-42sx52tn 91 28 of of IN cord-288072-42sx52tn 91 29 infections infection NNS cord-288072-42sx52tn 91 30 in in IN cord-288072-42sx52tn 91 31 1968 1968 CD cord-288072-42sx52tn 91 32 . . . cord-288072-42sx52tn 92 1 It -PRON- PRP cord-288072-42sx52tn 92 2 seemed seem VBD cord-288072-42sx52tn 92 3 possible possible JJ cord-288072-42sx52tn 92 4 that that IN cord-288072-42sx52tn 92 5 agents agent NNS cord-288072-42sx52tn 92 6 similar similar JJ cord-288072-42sx52tn 92 7 to to IN cord-288072-42sx52tn 92 8 OC43 OC43 NNP cord-288072-42sx52tn 92 9 might may MD cord-288072-42sx52tn 92 10 have have VB cord-288072-42sx52tn 92 11 been be VBN cord-288072-42sx52tn 92 12 responsible responsible JJ cord-288072-42sx52tn 92 13 for for IN cord-288072-42sx52tn 92 14 the the DT cord-288072-42sx52tn 92 15 1966 1966 CD cord-288072-42sx52tn 92 16 and and CC cord-288072-42sx52tn 92 17 1969 1969 CD cord-288072-42sx52tn 92 18 outbreaks outbreak NNS cord-288072-42sx52tn 92 19 and and CC cord-288072-42sx52tn 92 20 more more RBR cord-288072-42sx52tn 92 21 distantly distantly RB cord-288072-42sx52tn 92 22 related related JJ cord-288072-42sx52tn 92 23 agents agent NNS cord-288072-42sx52tn 92 24 for for IN cord-288072-42sx52tn 92 25 activity activity NN cord-288072-42sx52tn 92 26 at at IN cord-288072-42sx52tn 92 27 other other JJ cord-288072-42sx52tn 92 28 times time NNS cord-288072-42sx52tn 92 29 . . . cord-288072-42sx52tn 93 1 Such such PDT cord-288072-42sx52tn 93 2 a a DT cord-288072-42sx52tn 93 3 hypothesis hypothesis NN cord-288072-42sx52tn 93 4 could could MD cord-288072-42sx52tn 93 5 be be VB cord-288072-42sx52tn 93 6 tested test VBN cord-288072-42sx52tn 93 7 by by IN cord-288072-42sx52tn 93 8 evaluation evaluation NN cord-288072-42sx52tn 93 9 of of IN cord-288072-42sx52tn 93 10 the the DT cord-288072-42sx52tn 93 11 specificity specificity NN cord-288072-42sx52tn 93 12 of of IN cord-288072-42sx52tn 93 13 observed observed JJ cord-288072-42sx52tn 93 14 rises rise NNS cord-288072-42sx52tn 93 15 in in IN cord-288072-42sx52tn 93 16 titer titer NN cord-288072-42sx52tn 93 17 through through IN cord-288072-42sx52tn 93 18 use use NN cord-288072-42sx52tn 93 19 of of IN cord-288072-42sx52tn 93 20 the the DT cord-288072-42sx52tn 93 21 recently recently RB cord-288072-42sx52tn 93 22 described describe VBN cord-288072-42sx52tn 93 23 neutralization neutralization NN cord-288072-42sx52tn 93 24 test test NN cord-288072-42sx52tn 93 25 [ [ -LRB- cord-288072-42sx52tn 93 26 9 9 CD cord-288072-42sx52tn 93 27 ] ] -RRB- cord-288072-42sx52tn 93 28 . . . cord-288072-42sx52tn 94 1 Approximately approximately RB cord-288072-42sx52tn 94 2 Thereafter Thereafter NNP cord-288072-42sx52tn 94 3 the the DT cord-288072-42sx52tn 94 4 rates rate NNS cord-288072-42sx52tn 94 5 dropped drop VBD cord-288072-42sx52tn 94 6 , , , cord-288072-42sx52tn 94 7 showed show VBD cord-288072-42sx52tn 94 8 a a DT cord-288072-42sx52tn 94 9 suggestion suggestion NN cord-288072-42sx52tn 94 10 of of IN cord-288072-42sx52tn 94 11 an an DT cord-288072-42sx52tn 94 12 increase increase NN cord-288072-42sx52tn 94 13 in in IN cord-288072-42sx52tn 94 14 March March NNP cord-288072-42sx52tn 94 15 - - HYPH cord-288072-42sx52tn 94 16 April April NNP cord-288072-42sx52tn 94 17 1967 1967 CD cord-288072-42sx52tn 94 18 , , , cord-288072-42sx52tn 94 19 the the DT cord-288072-42sx52tn 94 20 period period NN cord-288072-42sx52tn 94 21 of of IN cord-288072-42sx52tn 94 22 the the DT cord-288072-42sx52tn 94 23 229E 229e CD cord-288072-42sx52tn 94 24 outbreak outbreak NN cord-288072-42sx52tn 94 25 [ [ -LRB- cord-288072-42sx52tn 94 26 11 11 CD cord-288072-42sx52tn 94 27 ] ] -RRB- cord-288072-42sx52tn 94 28 , , , cord-288072-42sx52tn 94 29 and and CC cord-288072-42sx52tn 94 30 then then RB cord-288072-42sx52tn 94 31 remained remain VBD cord-288072-42sx52tn 94 32 low low JJ cord-288072-42sx52tn 94 33 until until IN cord-288072-42sx52tn 94 34 March March NNP cord-288072-42sx52tn 94 35 - - HYPH cord-288072-42sx52tn 94 36 April April NNP cord-288072-42sx52tn 94 37 1968 1968 CD cord-288072-42sx52tn 94 38 . . . cord-288072-42sx52tn 95 1 This this DT cord-288072-42sx52tn 95 2 peak peak NN cord-288072-42sx52tn 95 3 of of IN cord-288072-42sx52tn 95 4 infection infection NN cord-288072-42sx52tn 95 5 was be VBD cord-288072-42sx52tn 95 6 detected detect VBN cord-288072-42sx52tn 95 7 by by IN cord-288072-42sx52tn 95 8 both both DT cord-288072-42sx52tn 95 9 serologic serologic JJ cord-288072-42sx52tn 95 10 tests test NNS cord-288072-42sx52tn 95 11 with with IN cord-288072-42sx52tn 95 12 the the DT cord-288072-42sx52tn 95 13 rate rate NN cord-288072-42sx52tn 95 14 by by IN cord-288072-42sx52tn 95 15 CF CF NNP cord-288072-42sx52tn 95 16 twice twice PDT cord-288072-42sx52tn 95 17 that that DT cord-288072-42sx52tn 95 18 by by IN cord-288072-42sx52tn 95 19 HAl HAl NNS cord-288072-42sx52tn 95 20 . . . cord-288072-42sx52tn 96 1 After after IN cord-288072-42sx52tn 96 2 this this DT cord-288072-42sx52tn 96 3 point point NN cord-288072-42sx52tn 96 4 the the DT cord-288072-42sx52tn 96 5 rates rate NNS cord-288072-42sx52tn 96 6 dropped drop VBD cord-288072-42sx52tn 96 7 only only RB cord-288072-42sx52tn 96 8 to to TO cord-288072-42sx52tn 96 9 peak peak VB cord-288072-42sx52tn 96 10 in in IN cord-288072-42sx52tn 96 11 1969 1969 CD cord-288072-42sx52tn 96 12 , , , cord-288072-42sx52tn 96 13 again again RB cord-288072-42sx52tn 96 14 in in IN cord-288072-42sx52tn 96 15 March March NNP cord-288072-42sx52tn 96 16 - - HYPH cord-288072-42sx52tn 96 17 April April NNP cord-288072-42sx52tn 96 18 . . . cord-288072-42sx52tn 97 1 During during IN cord-288072-42sx52tn 97 2 this this DT cord-288072-42sx52tn 97 3 outbreak outbreak NN cord-288072-42sx52tn 97 4 rates rate NNS cord-288072-42sx52tn 97 5 of of IN cord-288072-42sx52tn 97 6 incidence incidence NN cord-288072-42sx52tn 97 7 were be VBD cord-288072-42sx52tn 97 8 very very RB cord-288072-42sx52tn 97 9 high high JJ cord-288072-42sx52tn 97 10 , , , cord-288072-42sx52tn 97 11 with with IN cord-288072-42sx52tn 97 12 considerably considerably RB cord-288072-42sx52tn 97 13 more more JJR cord-288072-42sx52tn 97 14 infections infection NNS cord-288072-42sx52tn 97 15 detected detect VBN cord-288072-42sx52tn 97 16 by by IN cord-288072-42sx52tn 97 17 HAl HAl NNS cord-288072-42sx52tn 97 18 than than IN cord-288072-42sx52tn 97 19 by by IN cord-288072-42sx52tn 97 20 CF CF NNP cord-288072-42sx52tn 97 21 . . . cord-288072-42sx52tn 98 1 During during IN cord-288072-42sx52tn 98 2 the the DT cord-288072-42sx52tn 98 3 four four CD cord-288072-42sx52tn 98 4 years year NNS cord-288072-42sx52tn 98 5 studied study VBN cord-288072-42sx52tn 98 6 , , , cord-288072-42sx52tn 98 7 156 156 CD cord-288072-42sx52tn 98 8 paired pair VBN cord-288072-42sx52tn 98 9 specimens specimen NNS cord-288072-42sx52tn 98 10 showed show VBD cord-288072-42sx52tn 98 11 a a DT cord-288072-42sx52tn 98 12 rise rise NN cord-288072-42sx52tn 98 13 in in IN cord-288072-42sx52tn 98 14 titer titer NN cord-288072-42sx52tn 98 15 by by IN cord-288072-42sx52tn 98 16 CF CF NNP cord-288072-42sx52tn 98 17 and/or and/or CC cord-288072-42sx52tn 98 18 HAl HAl NNP cord-288072-42sx52tn 98 19 ; ; : cord-288072-42sx52tn 98 20 of of IN cord-288072-42sx52tn 98 21 these these DT cord-288072-42sx52tn 98 22 , , , cord-288072-42sx52tn 98 23 only only RB cord-288072-42sx52tn 98 24 37 37 CD cord-288072-42sx52tn 98 25 ( ( -LRB- cord-288072-42sx52tn 98 26 23.7 23.7 CD cord-288072-42sx52tn 98 27 % % NN cord-288072-42sx52tn 98 28 ) ) -RRB- cord-288072-42sx52tn 98 29 had have VBD cord-288072-42sx52tn 98 30 a a DT cord-288072-42sx52tn 98 31 rise rise NN cord-288072-42sx52tn 98 32 in in IN cord-288072-42sx52tn 98 33 titer titer NN cord-288072-42sx52tn 98 34 by by IN cord-288072-42sx52tn 98 35 both both DT cord-288072-42sx52tn 98 36 techniques technique NNS cord-288072-42sx52tn 98 37 . . . cord-288072-42sx52tn 99 1 This this DT cord-288072-42sx52tn 99 2 divergence divergence NN cord-288072-42sx52tn 99 3 in in IN cord-288072-42sx52tn 99 4 serologic serologic JJ cord-288072-42sx52tn 99 5 results result NNS cord-288072-42sx52tn 99 6 , , , cord-288072-42sx52tn 99 7 which which WDT cord-288072-42sx52tn 99 8 has have VBZ cord-288072-42sx52tn 99 9 been be VBN cord-288072-42sx52tn 99 10 noted note VBN cord-288072-42sx52tn 99 11 in in IN cord-288072-42sx52tn 99 12 previous previous JJ cord-288072-42sx52tn 99 13 studies study NNS cord-288072-42sx52tn 99 14 of of IN cord-288072-42sx52tn 99 15 OC43 OC43 NNP cord-288072-42sx52tn 99 16 virus virus NN cord-288072-42sx52tn 99 17 [ [ -LRB- cord-288072-42sx52tn 99 18 4 4 CD cord-288072-42sx52tn 99 19 ] ] -RRB- cord-288072-42sx52tn 99 20 , , , cord-288072-42sx52tn 99 21 was be VBD cord-288072-42sx52tn 99 22 not not RB cord-288072-42sx52tn 99 23 uniformly uniformly RB cord-288072-42sx52tn 99 24 spread spread VBN cord-288072-42sx52tn 99 25 over over IN cord-288072-42sx52tn 99 26 the the DT cord-288072-42sx52tn 99 27 full full JJ cord-288072-42sx52tn 99 28 period period NN cord-288072-42sx52tn 99 29 . . . cord-288072-42sx52tn 100 1 As as IN cord-288072-42sx52tn 100 2 shown show VBN cord-288072-42sx52tn 100 3 by by IN cord-288072-42sx52tn 100 4 the the DT cord-288072-42sx52tn 100 5 relative relative JJ cord-288072-42sx52tn 100 6 height height NN cord-288072-42sx52tn 100 7 of of IN cord-288072-42sx52tn 100 8 the the DT cord-288072-42sx52tn 100 9 bars bar NNS cord-288072-42sx52tn 100 10 in in IN cord-288072-42sx52tn 100 11 figure figure NN cord-288072-42sx52tn 100 12 1 1 CD cord-288072-42sx52tn 100 13 , , , cord-288072-42sx52tn 100 14 agreement agreement NN cord-288072-42sx52tn 100 15 between between IN cord-288072-42sx52tn 100 16 the the DT cord-288072-42sx52tn 100 17 two two CD cord-288072-42sx52tn 100 18 serologic serologic NNP cord-288072-42sx52tn 100 19 tests test NNS cord-288072-42sx52tn 100 20 was be VBD cord-288072-42sx52tn 100 21 an an DT cord-288072-42sx52tn 100 22 infrequent infrequent JJ cord-288072-42sx52tn 100 23 occurrence occurrence NN cord-288072-42sx52tn 100 24 except except IN cord-288072-42sx52tn 100 25 in in IN cord-288072-42sx52tn 100 26 May May NNP cord-288072-42sx52tn 100 27 - - HYPH cord-288072-42sx52tn 100 28 June June NNP cord-288072-42sx52tn 100 29 1966 1966 CD cord-288072-42sx52tn 100 30 and and CC cord-288072-42sx52tn 100 31 again again RB cord-288072-42sx52tn 100 32 in in IN cord-288072-42sx52tn 100 33 1969 1969 CD cord-288072-42sx52tn 100 34 . . . cord-288072-42sx52tn 101 1 During during IN cord-288072-42sx52tn 101 2 these these DT cord-288072-42sx52tn 101 3 periods period NNS cord-288072-42sx52tn 101 4 the the DT cord-288072-42sx52tn 101 5 percentage percentage NN cord-288072-42sx52tn 101 6 of of IN cord-288072-42sx52tn 101 7 positive positive JJ cord-288072-42sx52tn 101 8 paired pair VBN cord-288072-42sx52tn 101 9 specimens specimen NNS cord-288072-42sx52tn 101 10 in in IN cord-288072-42sx52tn 101 11 which which WDT cord-288072-42sx52tn 101 12 the the DT cord-288072-42sx52tn 101 13 rises rise NNS cord-288072-42sx52tn 101 14 occurred occur VBD cord-288072-42sx52tn 101 15 together together RB cord-288072-42sx52tn 101 16 was be VBD cord-288072-42sx52tn 101 17 39.2 39.2 CD cord-288072-42sx52tn 101 18 % % NN cord-288072-42sx52tn 101 19 , , , cord-288072-42sx52tn 101 20 but but CC cord-288072-42sx52tn 101 21 in in IN cord-288072-42sx52tn 101 22 the the DT cord-288072-42sx52tn 101 23 rest rest NN cord-288072-42sx52tn 101 24 of of IN cord-288072-42sx52tn 101 25 the the DT cord-288072-42sx52tn 101 26 four four CD cord-288072-42sx52tn 101 27 years year NNS cord-288072-42sx52tn 101 28 it -PRON- PRP cord-288072-42sx52tn 101 29 was be VBD cord-288072-42sx52tn 101 30 9.8 9.8 CD cord-288072-42sx52tn 101 31 % % NN cord-288072-42sx52tn 101 32 . . . cord-288072-42sx52tn 102 1 Even even RB cord-288072-42sx52tn 102 2 during during IN cord-288072-42sx52tn 102 3 March March NNP cord-288072-42sx52tn 102 4 - - HYPH cord-288072-42sx52tn 102 5 April April NNP cord-288072-42sx52tn 102 6 1968 1968 CD cord-288072-42sx52tn 102 7 , , , cord-288072-42sx52tn 102 8 when when WRB cord-288072-42sx52tn 102 9 a a DT cord-288072-42sx52tn 102 10 peak peak NN cord-288072-42sx52tn 102 11 of of IN cord-288072-42sx52tn 102 12 infections infection NNS cord-288072-42sx52tn 102 13 occurred occur VBD cord-288072-42sx52tn 102 14 , , , cord-288072-42sx52tn 102 15 there there EX cord-288072-42sx52tn 102 16 was be VBD cord-288072-42sx52tn 102 17 still still RB cord-288072-42sx52tn 102 18 little little JJ cord-288072-42sx52tn 102 19 correlation correlation NN cord-288072-42sx52tn 102 20 between between IN cord-288072-42sx52tn 102 21 the the DT cord-288072-42sx52tn 102 22 two two CD cord-288072-42sx52tn 102 23 tests test NNS cord-288072-42sx52tn 102 24 . . . cord-288072-42sx52tn 103 1 Age age NN cord-288072-42sx52tn 103 2 - - HYPH cord-288072-42sx52tn 103 3 specific specific JJ cord-288072-42sx52tn 103 4 occurrence occurrence NN cord-288072-42sx52tn 103 5 of of IN cord-288072-42sx52tn 103 6 infection infection NN cord-288072-42sx52tn 103 7 . . . cord-288072-42sx52tn 104 1 Results result NNS cord-288072-42sx52tn 104 2 of of IN cord-288072-42sx52tn 104 3 past past JJ cord-288072-42sx52tn 104 4 investigations investigation NNS cord-288072-42sx52tn 104 5 have have VBP cord-288072-42sx52tn 104 6 suggested suggest VBN cord-288072-42sx52tn 104 7 that that IN cord-288072-42sx52tn 104 8 age age NN cord-288072-42sx52tn 104 9 may may MD cord-288072-42sx52tn 104 10 be be VB cord-288072-42sx52tn 104 11 a a DT cord-288072-42sx52tn 104 12 factor factor NN cord-288072-42sx52tn 104 13 in in IN cord-288072-42sx52tn 104 14 producing produce VBG cord-288072-42sx52tn 104 15 differences difference NNS cord-288072-42sx52tn 104 16 in in IN cord-288072-42sx52tn 104 17 sensitivity sensitivity NN cord-288072-42sx52tn 104 18 of of IN cord-288072-42sx52tn 104 19 the the DT cord-288072-42sx52tn 104 20 CF cf NN cord-288072-42sx52tn 104 21 and and CC cord-288072-42sx52tn 104 22 HAl hal JJ cord-288072-42sx52tn 104 23 tests test NNS cord-288072-42sx52tn 104 24 ; ; : cord-288072-42sx52tn 104 25 CF CF NNP cord-288072-42sx52tn 104 26 was be VBD cord-288072-42sx52tn 104 27 found find VBN cord-288072-42sx52tn 104 28 to to TO cord-288072-42sx52tn 104 29 be be VB cord-288072-42sx52tn 104 30 most most RBS cord-288072-42sx52tn 104 31 sensitive sensitive JJ cord-288072-42sx52tn 104 32 when when WRB cord-288072-42sx52tn 104 33 the the DT cord-288072-42sx52tn 104 34 population population NN cord-288072-42sx52tn 104 35 studied study VBD cord-288072-42sx52tn 104 36 was be VBD cord-288072-42sx52tn 104 37 composed compose VBN cord-288072-42sx52tn 104 38 of of IN cord-288072-42sx52tn 104 39 adults adult NNS cord-288072-42sx52tn 104 40 [ [ -LRB- cord-288072-42sx52tn 104 41 9 9 CD cord-288072-42sx52tn 104 42 ] ] -RRB- cord-288072-42sx52tn 104 43 , , , cord-288072-42sx52tn 104 44 and and CC cord-288072-42sx52tn 104 45 HAl HAl NNPS cord-288072-42sx52tn 104 46 was be VBD cord-288072-42sx52tn 104 47 most most RBS cord-288072-42sx52tn 104 48 sensitive sensitive JJ cord-288072-42sx52tn 104 49 when when WRB cord-288072-42sx52tn 104 50 the the DT cord-288072-42sx52tn 104 51 population population NN cord-288072-42sx52tn 104 52 was be VBD cord-288072-42sx52tn 104 53 made make VBN cord-288072-42sx52tn 104 54 up up RP cord-288072-42sx52tn 104 55 exclusively exclusively RB cord-288072-42sx52tn 104 56 of of IN cord-288072-42sx52tn 104 57 children child NNS cord-288072-42sx52tn 104 58 [ [ -LRB- cord-288072-42sx52tn 104 59 4 4 CD cord-288072-42sx52tn 104 60 ] ] -RRB- cord-288072-42sx52tn 104 61 . . . cord-288072-42sx52tn 105 1 The the DT cord-288072-42sx52tn 105 2 ages age NNS cord-288072-42sx52tn 105 3 of of IN cord-288072-42sx52tn 105 4 individuals individual NNS cord-288072-42sx52tn 105 5 who who WP cord-288072-42sx52tn 105 6 exhibited exhibit VBD cord-288072-42sx52tn 105 7 the the DT cord-288072-42sx52tn 105 8 rises rise NNS cord-288072-42sx52tn 105 9 in in IN cord-288072-42sx52tn 105 10 titer titer NN cord-288072-42sx52tn 105 11 were be VBD cord-288072-42sx52tn 105 12 therefore therefore RB cord-288072-42sx52tn 105 13 examined examine VBN cord-288072-42sx52tn 105 14 , , , cord-288072-42sx52tn 105 15 showed show VBD cord-288072-42sx52tn 105 16 rises rise NNS cord-288072-42sx52tn 105 17 in in IN cord-288072-42sx52tn 105 18 antibody antibody NN cord-288072-42sx52tn 105 19 by by IN cord-288072-42sx52tn 105 20 CF CF NNP cord-288072-42sx52tn 105 21 and and CC cord-288072-42sx52tn 105 22 HAl HAl NNPS cord-288072-42sx52tn 105 23 were be VBD cord-288072-42sx52tn 105 24 tested test VBN cord-288072-42sx52tn 105 25 by by IN cord-288072-42sx52tn 105 26 neutralization neutralization NN cord-288072-42sx52tn 105 27 . . . cord-288072-42sx52tn 106 1 They -PRON- PRP cord-288072-42sx52tn 106 2 were be VBD cord-288072-42sx52tn 106 3 selected select VBN cord-288072-42sx52tn 106 4 randomly randomly RB cord-288072-42sx52tn 106 5 from from IN cord-288072-42sx52tn 106 6 within within IN cord-288072-42sx52tn 106 7 individual individual JJ cord-288072-42sx52tn 106 8 respiratory respiratory JJ cord-288072-42sx52tn 106 9 years year NNS cord-288072-42sx52tn 106 10 so so IN cord-288072-42sx52tn 106 11 that that IN cord-288072-42sx52tn 106 12 all all DT cord-288072-42sx52tn 106 13 periods period NNS cord-288072-42sx52tn 106 14 would would MD cord-288072-42sx52tn 106 15 be be VB cord-288072-42sx52tn 106 16 represented represent VBN cord-288072-42sx52tn 106 17 ; ; : cord-288072-42sx52tn 106 18 the the DT cord-288072-42sx52tn 106 19 respiratory respiratory JJ cord-288072-42sx52tn 106 20 year year NN cord-288072-42sx52tn 106 21 has have VBZ cord-288072-42sx52tn 106 22 been be VBN cord-288072-42sx52tn 106 23 defined define VBN cord-288072-42sx52tn 106 24 as as IN cord-288072-42sx52tn 106 25 extending extend VBG cord-288072-42sx52tn 106 26 from from IN cord-288072-42sx52tn 106 27 September September NNP cord-288072-42sx52tn 106 28 to to IN cord-288072-42sx52tn 106 29 the the DT cord-288072-42sx52tn 106 30 following follow VBG cord-288072-42sx52tn 106 31 August August NNP cord-288072-42sx52tn 106 32 and and CC cord-288072-42sx52tn 106 33 is be VBZ cord-288072-42sx52tn 106 34 identified identify VBN cord-288072-42sx52tn 106 35 by by IN cord-288072-42sx52tn 106 36 the the DT cord-288072-42sx52tn 106 37 date date NN cord-288072-42sx52tn 106 38 in in IN cord-288072-42sx52tn 106 39 which which WDT cord-288072-42sx52tn 106 40 most most JJS cord-288072-42sx52tn 106 41 of of IN cord-288072-42sx52tn 106 42 the the DT cord-288072-42sx52tn 106 43 year year NN cord-288072-42sx52tn 106 44 fell fall VBD cord-288072-42sx52tn 106 45 . . . cord-288072-42sx52tn 107 1 Results result NNS cord-288072-42sx52tn 107 2 are be VBP cord-288072-42sx52tn 107 3 given give VBN cord-288072-42sx52tn 107 4 in in IN cord-288072-42sx52tn 107 5 table table NN cord-288072-42sx52tn 107 6 2 2 CD cord-288072-42sx52tn 107 7 . . . cord-288072-42sx52tn 108 1 Period period NN cord-288072-42sx52tn 108 2 of of IN cord-288072-42sx52tn 108 3 collection collection NN cord-288072-42sx52tn 108 4 was be VBD cord-288072-42sx52tn 108 5 the the DT cord-288072-42sx52tn 108 6 most most RBS cord-288072-42sx52tn 108 7 important important JJ cord-288072-42sx52tn 108 8 predictor predictor NN cord-288072-42sx52tn 108 9 of of IN cord-288072-42sx52tn 108 10 presence presence NN cord-288072-42sx52tn 108 11 or or CC cord-288072-42sx52tn 108 12 absence absence NN cord-288072-42sx52tn 108 13 of of IN cord-288072-42sx52tn 108 14 rise rise NN cord-288072-42sx52tn 108 15 in in IN cord-288072-42sx52tn 108 16 titer titer NN cord-288072-42sx52tn 108 17 of of IN cord-288072-42sx52tn 108 18 neutralizing neutralize VBG cord-288072-42sx52tn 108 19 antibody antibody NN cord-288072-42sx52tn 108 20 . . . cord-288072-42sx52tn 109 1 Since since IN cord-288072-42sx52tn 109 2 the the DT cord-288072-42sx52tn 109 3 1966 1966 CD cord-288072-42sx52tn 109 4 and and CC cord-288072-42sx52tn 109 5 1969 1969 CD cord-288072-42sx52tn 109 6 periods period NNS cord-288072-42sx52tn 109 7 , , , cord-288072-42sx52tn 109 8 on on IN cord-288072-42sx52tn 109 9 the the DT cord-288072-42sx52tn 109 10 one one CD cord-288072-42sx52tn 109 11 hand hand NN cord-288072-42sx52tn 109 12 , , , cord-288072-42sx52tn 109 13 and and CC cord-288072-42sx52tn 109 14 the the DT cord-288072-42sx52tn 109 15 1967 1967 CD cord-288072-42sx52tn 109 16 and and CC cord-288072-42sx52tn 109 17 1968 1968 CD cord-288072-42sx52tn 109 18 periods period NNS cord-288072-42sx52tn 109 19 , , , cord-288072-42sx52tn 109 20 on on IN cord-288072-42sx52tn 109 21 the the DT cord-288072-42sx52tn 109 22 other other JJ cord-288072-42sx52tn 109 23 , , , cord-288072-42sx52tn 109 24 resembled resemble VBD cord-288072-42sx52tn 109 25 each each DT cord-288072-42sx52tn 109 26 other other JJ cord-288072-42sx52tn 109 27 , , , cord-288072-42sx52tn 109 28 they -PRON- PRP cord-288072-42sx52tn 109 29 have have VBP cord-288072-42sx52tn 109 30 been be VBN cord-288072-42sx52tn 109 31 combined combine VBN cord-288072-42sx52tn 109 32 . . . cord-288072-42sx52tn 110 1 In in IN cord-288072-42sx52tn 110 2 serum serum NN cord-288072-42sx52tn 110 3 pairs pair NNS cord-288072-42sx52tn 110 4 in in IN cord-288072-42sx52tn 110 5 which which WDT cord-288072-42sx52tn 110 6 the the DT cord-288072-42sx52tn 110 7 second second JJ cord-288072-42sx52tn 110 8 specimen specimen NN cord-288072-42sx52tn 110 9 was be VBD cord-288072-42sx52tn 110 10 collected collect VBN cord-288072-42sx52tn 110 11 in in IN cord-288072-42sx52tn 110 12 1967 1967 CD cord-288072-42sx52tn 110 13 and and CC cord-288072-42sx52tn 110 14 1968 1968 CD cord-288072-42sx52tn 110 15 , , , cord-288072-42sx52tn 110 16 and and CC cord-288072-42sx52tn 110 17 in in IN cord-288072-42sx52tn 110 18 which which WDT cord-288072-42sx52tn 110 19 there there EX cord-288072-42sx52tn 110 20 was be VBD cord-288072-42sx52tn 110 21 a a DT cord-288072-42sx52tn 110 22 rise rise NN cord-288072-42sx52tn 110 23 in in IN cord-288072-42sx52tn 110 24 CF cf NN cord-288072-42sx52tn 110 25 titer titer NN cord-288072-42sx52tn 110 26 alone alone RB cord-288072-42sx52tn 110 27 , , , cord-288072-42sx52tn 110 28 no no DT cord-288072-42sx52tn 110 29 rises rise NNS cord-288072-42sx52tn 110 30 in in IN cord-288072-42sx52tn 110 31 titers titer NNS cord-288072-42sx52tn 110 32 of of IN cord-288072-42sx52tn 110 33 neutralizing neutralize VBG cord-288072-42sx52tn 110 34 antibody antibody NN cord-288072-42sx52tn 110 35 were be VBD cord-288072-42sx52tn 110 36 found find VBN cord-288072-42sx52tn 110 37 . . . cord-288072-42sx52tn 111 1 In in IN cord-288072-42sx52tn 111 2 the the DT cord-288072-42sx52tn 111 3 pairs pair NNS cord-288072-42sx52tn 111 4 from from IN cord-288072-42sx52tn 111 5 this this DT cord-288072-42sx52tn 111 6 period period NN cord-288072-42sx52tn 111 7 with with IN cord-288072-42sx52tn 111 8 a a DT cord-288072-42sx52tn 111 9 rise rise NN cord-288072-42sx52tn 111 10 in in IN cord-288072-42sx52tn 111 11 HAl hal JJ cord-288072-42sx52tn 111 12 antibody antibody NN cord-288072-42sx52tn 111 13 , , , cord-288072-42sx52tn 111 14 there there EX cord-288072-42sx52tn 111 15 was be VBD cord-288072-42sx52tn 111 16 an an DT cord-288072-42sx52tn 111 17 occasional occasional JJ cord-288072-42sx52tn 111 18 rise rise NN cord-288072-42sx52tn 111 19 in in IN cord-288072-42sx52tn 111 20 titer titer NN cord-288072-42sx52tn 111 21 of of IN cord-288072-42sx52tn 111 22 neutralizing neutralize VBG cord-288072-42sx52tn 111 23 antibody antibody NN cord-288072-42sx52tn 111 24 , , , cord-288072-42sx52tn 111 25 and and CC cord-288072-42sx52tn 111 26 among among IN cord-288072-42sx52tn 111 27 the the DT cord-288072-42sx52tn 111 28 few few JJ cord-288072-42sx52tn 111 29 pairs pair NNS cord-288072-42sx52tn 111 30 showing show VBG cord-288072-42sx52tn 111 31 an an DT cord-288072-42sx52tn 111 32 increase increase NN cord-288072-42sx52tn 111 33 in in IN cord-288072-42sx52tn 111 34 titer titer NN cord-288072-42sx52tn 111 35 by by IN cord-288072-42sx52tn 111 36 both both CC cord-288072-42sx52tn 111 37 CF CF NNP cord-288072-42sx52tn 111 38 and and CC cord-288072-42sx52tn 111 39 HAl HAl NNP cord-288072-42sx52tn 111 40 , , , cord-288072-42sx52tn 111 41 28.6 28.6 CD cord-288072-42sx52tn 111 42 % % NN cord-288072-42sx52tn 111 43 had have VBD cord-288072-42sx52tn 111 44 a a DT cord-288072-42sx52tn 111 45 rise rise NN cord-288072-42sx52tn 111 46 in in IN cord-288072-42sx52tn 111 47 titer titer NN cord-288072-42sx52tn 111 48 by by IN cord-288072-42sx52tn 111 49 neutralization neutralization NN cord-288072-42sx52tn 111 50 . . . cord-288072-42sx52tn 112 1 The the DT cord-288072-42sx52tn 112 2 situation situation NN cord-288072-42sx52tn 112 3 with with IN cord-288072-42sx52tn 112 4 the the DT cord-288072-42sx52tn 112 5 1966 1966 CD cord-288072-42sx52tn 112 6 and and CC cord-288072-42sx52tn 112 7 1969 1969 CD cord-288072-42sx52tn 112 8 specimens specimen NNS cord-288072-42sx52tn 112 9 was be VBD cord-288072-42sx52tn 112 10 quite quite RB cord-288072-42sx52tn 112 11 different different JJ cord-288072-42sx52tn 112 12 . . . cord-288072-42sx52tn 113 1 The the DT cord-288072-42sx52tn 113 2 specimens specimen NNS cord-288072-42sx52tn 113 3 with with IN cord-288072-42sx52tn 113 4 rises rise NNS cord-288072-42sx52tn 113 5 in in IN cord-288072-42sx52tn 113 6 CF CF NNP cord-288072-42sx52tn 113 7 or or CC cord-288072-42sx52tn 113 8 HAl hal JJ cord-288072-42sx52tn 113 9 titer titer NN cord-288072-42sx52tn 113 10 both both DT cord-288072-42sx52tn 113 11 showed show VBD cord-288072-42sx52tn 113 12 66.7 66.7 CD cord-288072-42sx52tn 113 13 % % NN cord-288072-42sx52tn 113 14 agreement agreement NN cord-288072-42sx52tn 113 15 with with IN cord-288072-42sx52tn 113 16 the the DT cord-288072-42sx52tn 113 17 neutralization neutralization NN cord-288072-42sx52tn 113 18 test test NN cord-288072-42sx52tn 113 19 . . . cord-288072-42sx52tn 114 1 All all DT cord-288072-42sx52tn 114 2 specimens specimen NNS cord-288072-42sx52tn 114 3 with with IN cord-288072-42sx52tn 114 4 a a DT cord-288072-42sx52tn 114 5 combined combine VBN cord-288072-42sx52tn 114 6 CF cf NN cord-288072-42sx52tn 114 7 and and CC cord-288072-42sx52tn 114 8 HAl hal JJ cord-288072-42sx52tn 114 9 increase increase NN cord-288072-42sx52tn 114 10 also also RB cord-288072-42sx52tn 114 11 had have VBD cord-288072-42sx52tn 114 12 a a DT cord-288072-42sx52tn 114 13 rise rise NN cord-288072-42sx52tn 114 14 in in IN cord-288072-42sx52tn 114 15 titer titer NN cord-288072-42sx52tn 114 16 by by IN cord-288072-42sx52tn 114 17 neutralization neutralization NN cord-288072-42sx52tn 114 18 . . . cord-288072-42sx52tn 115 1 Thus thus RB cord-288072-42sx52tn 115 2 , , , cord-288072-42sx52tn 115 3 the the DT cord-288072-42sx52tn 115 4 1966 1966 CD cord-288072-42sx52tn 115 5 and and CC cord-288072-42sx52tn 115 6 1969 1969 CD cord-288072-42sx52tn 115 7 period period NN cord-288072-42sx52tn 115 8 was be VBD cord-288072-42sx52tn 115 9 distinct distinct JJ cord-288072-42sx52tn 115 10 from from IN cord-288072-42sx52tn 115 11 the the DT cord-288072-42sx52tn 115 12 1967 1967 CD cord-288072-42sx52tn 115 13 and and CC cord-288072-42sx52tn 115 14 1968 1968 CD cord-288072-42sx52tn 115 15 period period NN cord-288072-42sx52tn 115 16 in in IN cord-288072-42sx52tn 115 17 having have VBG cord-288072-42sx52tn 115 18 not not RB cord-288072-42sx52tn 115 19 only only RB cord-288072-42sx52tn 115 20 more more RBR cord-288072-42sx52tn 115 21 frequent frequent JJ cord-288072-42sx52tn 115 22 combined combine VBN cord-288072-42sx52tn 115 23 CF cf NN cord-288072-42sx52tn 115 24 and and CC cord-288072-42sx52tn 115 25 HAl HAl NNP cord-288072-42sx52tn 115 26 rises rise VBZ cord-288072-42sx52tn 115 27 in in IN cord-288072-42sx52tn 115 28 antibody antibody NN cord-288072-42sx52tn 115 29 titer titer NN cord-288072-42sx52tn 115 30 , , , cord-288072-42sx52tn 115 31 but but CC cord-288072-42sx52tn 115 32 also also RB cord-288072-42sx52tn 115 33 because because IN cord-288072-42sx52tn 115 34 all all DT cord-288072-42sx52tn 115 35 rises rise NNS cord-288072-42sx52tn 115 36 in in IN cord-288072-42sx52tn 115 37 antibody antibody NN cord-288072-42sx52tn 115 38 titer titer NN cord-288072-42sx52tn 115 39 were be VBD cord-288072-42sx52tn 115 40 more more RBR cord-288072-42sx52tn 115 41 likely likely RB cord-288072-42sx52tn 115 42 associated associate VBN cord-288072-42sx52tn 115 43 with with IN cord-288072-42sx52tn 115 44 rises rise NNS cord-288072-42sx52tn 115 45 in in IN cord-288072-42sx52tn 115 46 neutralization neutralization NN cord-288072-42sx52tn 115 47 titer titer NN cord-288072-42sx52tn 115 48 . . . cord-288072-42sx52tn 116 1 These these DT cord-288072-42sx52tn 116 2 findings finding NNS cord-288072-42sx52tn 116 3 confirm confirm VBP cord-288072-42sx52tn 116 4 that that IN cord-288072-42sx52tn 116 5 the the DT cord-288072-42sx52tn 116 6 1966 1966 CD cord-288072-42sx52tn 116 7 and and CC cord-288072-42sx52tn 116 8 1969 1969 CD cord-288072-42sx52tn 116 9 outbreaks outbreak NNS cord-288072-42sx52tn 116 10 were be VBD cord-288072-42sx52tn 116 11 caused cause VBN cord-288072-42sx52tn 116 12 by by IN cord-288072-42sx52tn 116 13 viruses virus NNS cord-288072-42sx52tn 116 14 more more RBR cord-288072-42sx52tn 116 15 closely closely RB cord-288072-42sx52tn 116 16 related related JJ cord-288072-42sx52tn 116 17 to to IN cord-288072-42sx52tn 116 18 OC43 OC43 NNP cord-288072-42sx52tn 116 19 than than IN cord-288072-42sx52tn 116 20 the the DT cord-288072-42sx52tn 116 21 viruses virus NNS cord-288072-42sx52tn 116 22 involved involve VBN cord-288072-42sx52tn 116 23 in in IN cord-288072-42sx52tn 116 24 infections infection NNS cord-288072-42sx52tn 116 25 during during IN cord-288072-42sx52tn 116 26 the the DT cord-288072-42sx52tn 116 27 1967 1967 CD cord-288072-42sx52tn 116 28 and and CC cord-288072-42sx52tn 116 29 1968 1968 CD cord-288072-42sx52tn 116 30 period period NN cord-288072-42sx52tn 116 31 . . . cord-288072-42sx52tn 117 1 During during IN cord-288072-42sx52tn 117 2 1967 1967 CD cord-288072-42sx52tn 117 3 , , , cord-288072-42sx52tn 117 4 a a DT cord-288072-42sx52tn 117 5 large large JJ cord-288072-42sx52tn 117 6 - - HYPH cord-288072-42sx52tn 117 7 scale scale NN cord-288072-42sx52tn 117 8 outbreak outbreak NN cord-288072-42sx52tn 117 9 of of IN cord-288072-42sx52tn 117 10 229E 229e CD cord-288072-42sx52tn 117 11 Monto Monto NNP cord-288072-42sx52tn 117 12 and and CC cord-288072-42sx52tn 117 13 Lim Lim NNP cord-288072-42sx52tn 117 14 virus virus NN cord-288072-42sx52tn 117 15 was be VBD cord-288072-42sx52tn 117 16 detected detect VBN cord-288072-42sx52tn 117 17 in in IN cord-288072-42sx52tn 117 18 Tecumseh Tecumseh NNP cord-288072-42sx52tn 117 19 [ [ -LRB- cord-288072-42sx52tn 117 20 11 11 CD cord-288072-42sx52tn 117 21 ] ] -RRB- cord-288072-42sx52tn 117 22 . . . cord-288072-42sx52tn 118 1 It -PRON- PRP cord-288072-42sx52tn 118 2 is be VBZ cord-288072-42sx52tn 118 3 possible possible JJ cord-288072-42sx52tn 118 4 that that IN cord-288072-42sx52tn 118 5 some some DT cord-288072-42sx52tn 118 6 of of IN cord-288072-42sx52tn 118 7 the the DT cord-288072-42sx52tn 118 8 rises rise NNS cord-288072-42sx52tn 118 9 in in IN cord-288072-42sx52tn 118 10 titer titer NN cord-288072-42sx52tn 118 11 of of IN cord-288072-42sx52tn 118 12 antibody antibody NN cord-288072-42sx52tn 118 13 to to IN cord-288072-42sx52tn 118 14 OC43 OC43 NNP cord-288072-42sx52tn 118 15 during during IN cord-288072-42sx52tn 118 16 1967 1967 CD cord-288072-42sx52tn 118 17 might may MD cord-288072-42sx52tn 118 18 represent represent VB cord-288072-42sx52tn 118 19 cross cross JJ cord-288072-42sx52tn 118 20 - - NNS cord-288072-42sx52tn 118 21 reactions reaction NNS cord-288072-42sx52tn 118 22 from from IN cord-288072-42sx52tn 118 23 an an DT cord-288072-42sx52tn 118 24 actual actual JJ cord-288072-42sx52tn 118 25 infection infection NN cord-288072-42sx52tn 118 26 with with IN cord-288072-42sx52tn 118 27 229E. 229E. NNP cord-288072-42sx52tn 119 1 Therefore therefore RB cord-288072-42sx52tn 119 2 , , , cord-288072-42sx52tn 119 3 the the DT cord-288072-42sx52tn 119 4 21 21 CD cord-288072-42sx52tn 119 5 sera sera NNP cord-288072-42sx52tn 119 6 with with IN cord-288072-42sx52tn 119 7 HAl HAl NNP cord-288072-42sx52tn 119 8 or or CC cord-288072-42sx52tn 119 9 CF CF NNP cord-288072-42sx52tn 119 10 rises rise VBZ cord-288072-42sx52tn 119 11 in in IN cord-288072-42sx52tn 119 12 titer titer NN cord-288072-42sx52tn 119 13 of of IN cord-288072-42sx52tn 119 14 OC43 OC43 NNP cord-288072-42sx52tn 119 15 antibody antibody NN cord-288072-42sx52tn 119 16 in in IN cord-288072-42sx52tn 119 17 1967 1967 CD cord-288072-42sx52tn 119 18 were be VBD cord-288072-42sx52tn 119 19 tested test VBN cord-288072-42sx52tn 119 20 by by IN cord-288072-42sx52tn 119 21 CF CF NNP cord-288072-42sx52tn 119 22 against against IN cord-288072-42sx52tn 119 23 a a DT cord-288072-42sx52tn 119 24 229E 229e CD cord-288072-42sx52tn 119 25 antigen antigen NN cord-288072-42sx52tn 119 26 . . . cord-288072-42sx52tn 120 1 Of of IN cord-288072-42sx52tn 120 2 those those DT cord-288072-42sx52tn 120 3 tested test VBN cord-288072-42sx52tn 120 4 , , , cord-288072-42sx52tn 120 5 only only RB cord-288072-42sx52tn 120 6 two two CD cord-288072-42sx52tn 120 7 ( ( -LRB- cord-288072-42sx52tn 120 8 9.5 9.5 CD cord-288072-42sx52tn 120 9 % % NN cord-288072-42sx52tn 120 10 ) ) -RRB- cord-288072-42sx52tn 120 11 showed show VBD cord-288072-42sx52tn 120 12 a a DT cord-288072-42sx52tn 120 13 rise rise NN cord-288072-42sx52tn 120 14 in in IN cord-288072-42sx52tn 120 15 titer titer NN cord-288072-42sx52tn 120 16 . . . cord-288072-42sx52tn 121 1 Since since IN cord-288072-42sx52tn 121 2 this this DT cord-288072-42sx52tn 121 3 CF cf NN cord-288072-42sx52tn 121 4 test test NN cord-288072-42sx52tn 121 5 is be VBZ cord-288072-42sx52tn 121 6 sensitive sensitive JJ cord-288072-42sx52tn 121 7 when when WRB cord-288072-42sx52tn 121 8 used use VBN cord-288072-42sx52tn 121 9 with with IN cord-288072-42sx52tn 121 10 sera sera NNP cord-288072-42sx52tn 121 11 collected collect VBD cord-288072-42sx52tn 121 12 close close RB cord-288072-42sx52tn 121 13 in in IN cord-288072-42sx52tn 121 14 time time NN cord-288072-42sx52tn 121 15 to to IN cord-288072-42sx52tn 121 16 infection infection NN cord-288072-42sx52tn 121 17 , , , cord-288072-42sx52tn 121 18 it -PRON- PRP cord-288072-42sx52tn 121 19 is be VBZ cord-288072-42sx52tn 121 20 probable probable JJ cord-288072-42sx52tn 121 21 that that IN cord-288072-42sx52tn 121 22 the the DT cord-288072-42sx52tn 121 23 agent agent NN cord-288072-42sx52tn 121 24 involved involve VBN cord-288072-42sx52tn 121 25 in in IN cord-288072-42sx52tn 121 26 producing produce VBG cord-288072-42sx52tn 121 27 the the DT cord-288072-42sx52tn 121 28 rises rise NNS cord-288072-42sx52tn 121 29 in in IN cord-288072-42sx52tn 121 30 OC43 OC43 NNP cord-288072-42sx52tn 121 31 titer titer NN cord-288072-42sx52tn 121 32 during during IN cord-288072-42sx52tn 121 33 1967 1967 CD cord-288072-42sx52tn 121 34 was be VBD cord-288072-42sx52tn 121 35 other other JJ cord-288072-42sx52tn 121 36 than than IN cord-288072-42sx52tn 121 37 229E. 229E. NNP cord-288072-42sx52tn 121 38 Study Study NNP cord-288072-42sx52tn 121 39 of of IN cord-288072-42sx52tn 121 40 the the DT cord-288072-42sx52tn 121 41 1969 1969 CD cord-288072-42sx52tn 121 42 outbreak outbreak NN cord-288072-42sx52tn 121 43 . . . cord-288072-42sx52tn 122 1 The the DT cord-288072-42sx52tn 122 2 outbreak outbreak NN cord-288072-42sx52tn 122 3 detected detect VBD cord-288072-42sx52tn 122 4 serologically serologically RB cord-288072-42sx52tn 122 5 in in IN cord-288072-42sx52tn 122 6 late late JJ cord-288072-42sx52tn 122 7 1968 1968 CD cord-288072-42sx52tn 122 8 and and CC cord-288072-42sx52tn 122 9 the the DT cord-288072-42sx52tn 122 10 first first JJ cord-288072-42sx52tn 122 11 part part NN cord-288072-42sx52tn 122 12 of of IN cord-288072-42sx52tn 122 13 1969 1969 CD cord-288072-42sx52tn 122 14 not not RB cord-288072-42sx52tn 122 15 only only RB cord-288072-42sx52tn 122 16 was be VBD cord-288072-42sx52tn 122 17 large large JJ cord-288072-42sx52tn 122 18 scale scale NN cord-288072-42sx52tn 122 19 , , , cord-288072-42sx52tn 122 20 but but CC cord-288072-42sx52tn 122 21 was be VBD cord-288072-42sx52tn 122 22 also also RB cord-288072-42sx52tn 122 23 probably probably RB cord-288072-42sx52tn 122 24 caused cause VBN cord-288072-42sx52tn 122 25 by by IN cord-288072-42sx52tn 122 26 an an DT cord-288072-42sx52tn 122 27 agent agent NN cord-288072-42sx52tn 122 28 related relate VBN cord-288072-42sx52tn 122 29 to to IN cord-288072-42sx52tn 122 30 OC43 OC43 NNP cord-288072-42sx52tn 122 31 . . . cord-288072-42sx52tn 123 1 To to TO cord-288072-42sx52tn 123 2 define define VB cord-288072-42sx52tn 123 3 better well RBR cord-288072-42sx52tn 123 4 the the DT cord-288072-42sx52tn 123 5 occurrence occurrence NN cord-288072-42sx52tn 123 6 of of IN cord-288072-42sx52tn 123 7 infection infection NN cord-288072-42sx52tn 123 8 during during IN cord-288072-42sx52tn 123 9 this this DT cord-288072-42sx52tn 123 10 period period NN cord-288072-42sx52tn 123 11 , , , cord-288072-42sx52tn 123 12 serologic serologic NNP cord-288072-42sx52tn 123 13 data datum NNS cord-288072-42sx52tn 123 14 from from IN cord-288072-42sx52tn 123 15 the the DT cord-288072-42sx52tn 123 16 106 106 CD cord-288072-42sx52tn 123 17 families family NNS cord-288072-42sx52tn 123 18 whose whose WP$ cord-288072-42sx52tn 123 19 second second JJ cord-288072-42sx52tn 123 20 and and CC cord-288072-42sx52tn 123 21 third third JJ cord-288072-42sx52tn 123 22 specimens specimen NNS cord-288072-42sx52tn 123 23 of of IN cord-288072-42sx52tn 123 24 blood blood NN cord-288072-42sx52tn 123 25 were be VBD cord-288072-42sx52tn 123 26 collected collect VBN cord-288072-42sx52tn 123 27 during during IN cord-288072-42sx52tn 123 28 the the DT cord-288072-42sx52tn 123 29 period period NN cord-288072-42sx52tn 123 30 from from IN cord-288072-42sx52tn 123 31 August August NNP cord-288072-42sx52tn 123 32 1968 1968 CD cord-288072-42sx52tn 123 33 to to IN cord-288072-42sx52tn 123 34 June June NNP cord-288072-42sx52tn 123 35 1969 1969 CD cord-288072-42sx52tn 123 36 were be VBD cord-288072-42sx52tn 123 37 examined examine VBN cord-288072-42sx52tn 123 38 separately separately RB cord-288072-42sx52tn 123 39 . . . cord-288072-42sx52tn 124 1 To to TO cord-288072-42sx52tn 124 2 complete complete VB cord-288072-42sx52tn 124 3 the the DT cord-288072-42sx52tn 124 4 study study NN cord-288072-42sx52tn 124 5 of of IN cord-288072-42sx52tn 124 6 these these DT cord-288072-42sx52tn 124 7 families family NNS cord-288072-42sx52tn 124 8 the the DT cord-288072-42sx52tn 124 9 blood blood NN cord-288072-42sx52tn 124 10 specimens specimen NNS cord-288072-42sx52tn 124 11 collected collect VBN cord-288072-42sx52tn 124 12 on on IN cord-288072-42sx52tn 124 13 filter filter NN cord-288072-42sx52tn 124 14 paper paper NN cord-288072-42sx52tn 124 15 disks disk NNS cord-288072-42sx52tn 124 16 from from IN cord-288072-42sx52tn 124 17 the the DT cord-288072-42sx52tn 124 18 younger young JJR cord-288072-42sx52tn 124 19 children child NNS cord-288072-42sx52tn 124 20 were be VBD cord-288072-42sx52tn 124 21 also also RB cord-288072-42sx52tn 124 22 tested test VBN cord-288072-42sx52tn 124 23 by by IN cord-288072-42sx52tn 124 24 CF CF NNP cord-288072-42sx52tn 124 25 and and CC cord-288072-42sx52tn 124 26 HAl HAl NNP cord-288072-42sx52tn 124 27 against against IN cord-288072-42sx52tn 124 28 OC43 OC43 NNP cord-288072-42sx52tn 124 29 antibody antibody NN cord-288072-42sx52tn 124 30 . . . cord-288072-42sx52tn 125 1 Persons person NNS cord-288072-42sx52tn 125 2 were be VBD cord-288072-42sx52tn 125 3 identified identify VBN cord-288072-42sx52tn 125 4 as as IN cord-288072-42sx52tn 125 5 infected infect VBN cord-288072-42sx52tn 125 6 if if IN cord-288072-42sx52tn 125 7 they -PRON- PRP cord-288072-42sx52tn 125 8 had have VBD cord-288072-42sx52tn 125 9 a a DT cord-288072-42sx52tn 125 10 significant significant JJ cord-288072-42sx52tn 125 11 increase increase NN cord-288072-42sx52tn 125 12 in in IN cord-288072-42sx52tn 125 13 antibody antibody NN cord-288072-42sx52tn 125 14 titer titer NN cord-288072-42sx52tn 125 15 by by IN cord-288072-42sx52tn 125 16 CF CF NNP cord-288072-42sx52tn 125 17 or or CC cord-288072-42sx52tn 125 18 HAl hal JJ cord-288072-42sx52tn 125 19 test test NN cord-288072-42sx52tn 125 20 , , , cord-288072-42sx52tn 125 21 since since IN cord-288072-42sx52tn 125 22 during during IN cord-288072-42sx52tn 125 23 the the DT cord-288072-42sx52tn 125 24 period period NN cord-288072-42sx52tn 125 25 both both DT cord-288072-42sx52tn 125 26 were be VBD cord-288072-42sx52tn 125 27 equally equally RB cord-288072-42sx52tn 125 28 likely likely JJ cord-288072-42sx52tn 125 29 to to TO cord-288072-42sx52tn 125 30 agree agree VB cord-288072-42sx52tn 125 31 with with IN cord-288072-42sx52tn 125 32 the the DT cord-288072-42sx52tn 125 33 neutralization neutralization NN cord-288072-42sx52tn 125 34 test test NN cord-288072-42sx52tn 125 35 . . . cord-288072-42sx52tn 126 1 The the DT cord-288072-42sx52tn 126 2 results result NNS cord-288072-42sx52tn 126 3 , , , cord-288072-42sx52tn 126 4 shown show VBN cord-288072-42sx52tn 126 5 in in IN cord-288072-42sx52tn 126 6 table table NN cord-288072-42sx52tn 126 7 3 3 CD cord-288072-42sx52tn 126 8 , , , cord-288072-42sx52tn 126 9 calculated calculate VBN cord-288072-42sx52tn 126 10 on on IN cord-288072-42sx52tn 126 11 the the DT cord-288072-42sx52tn 126 12 basis basis NN cord-288072-42sx52tn 126 13 of of IN cord-288072-42sx52tn 126 14 person person NN cord-288072-42sx52tn 126 15 - - HYPH cord-288072-42sx52tn 126 16 years year NNS cord-288072-42sx52tn 126 17 of of IN cord-288072-42sx52tn 126 18 observation observation NN cord-288072-42sx52tn 126 19 , , , cord-288072-42sx52tn 126 20 indicate indicate VBP cord-288072-42sx52tn 126 21 the the DT cord-288072-42sx52tn 126 22 great great JJ cord-288072-42sx52tn 126 23 frequency frequency NN cord-288072-42sx52tn 126 24 of of IN cord-288072-42sx52tn 126 25 infection infection NN cord-288072-42sx52tn 126 26 with with IN cord-288072-42sx52tn 126 27 the the DT cord-288072-42sx52tn 126 28 agent agent NN cord-288072-42sx52tn 126 29 . . . cord-288072-42sx52tn 127 1 Those those DT cord-288072-42sx52tn 127 2 under under IN cord-288072-42sx52tn 127 3 five five CD cord-288072-42sx52tn 127 4 years year NNS cord-288072-42sx52tn 127 5 of of IN cord-288072-42sx52tn 127 6 age age NN cord-288072-42sx52tn 127 7 showed show VBD cord-288072-42sx52tn 127 8 the the DT cord-288072-42sx52tn 127 9 highest high JJS cord-288072-42sx52tn 127 10 rates rate NNS cord-288072-42sx52tn 127 11 of of IN cord-288072-42sx52tn 127 12 infection infection NN cord-288072-42sx52tn 127 13 , , , cord-288072-42sx52tn 127 14 and and CC cord-288072-42sx52tn 127 15 the the DT cord-288072-42sx52tn 127 16 rates rate NNS cord-288072-42sx52tn 127 17 fell fall VBD cord-288072-42sx52tn 127 18 slightly slightly RB cord-288072-42sx52tn 127 19 as as IN cord-288072-42sx52tn 127 20 the the DT cord-288072-42sx52tn 127 21 age age NN cord-288072-42sx52tn 127 22 of of IN cord-288072-42sx52tn 127 23 children child NNS cord-288072-42sx52tn 127 24 increased increase VBD cord-288072-42sx52tn 127 25 . . . cord-288072-42sx52tn 128 1 Among among IN cord-288072-42sx52tn 128 2 adults adult NNS cord-288072-42sx52tn 128 3 , , , cord-288072-42sx52tn 128 4 the the DT cord-288072-42sx52tn 128 5 30 30 CD cord-288072-42sx52tn 128 6 - - HYPH cord-288072-42sx52tn 128 7 39-year 39-year JJ cord-288072-42sx52tn 128 8 age age NN cord-288072-42sx52tn 128 9 group group NN cord-288072-42sx52tn 128 10 had have VBD cord-288072-42sx52tn 128 11 the the DT cord-288072-42sx52tn 128 12 highest high JJS cord-288072-42sx52tn 128 13 rates rate NNS cord-288072-42sx52tn 128 14 . . . cord-288072-42sx52tn 129 1 The the DT cord-288072-42sx52tn 129 2 very very RB cord-288072-42sx52tn 129 3 high high JJ cord-288072-42sx52tn 129 4 rate rate NN cord-288072-42sx52tn 129 5 of of IN cord-288072-42sx52tn 129 6 infection infection NN cord-288072-42sx52tn 129 7 in in IN cord-288072-42sx52tn 129 8 adults adult NNS cord-288072-42sx52tn 129 9 was be VBD cord-288072-42sx52tn 129 10 similar similar JJ cord-288072-42sx52tn 129 11 to to IN cord-288072-42sx52tn 129 12 that that DT cord-288072-42sx52tn 129 13 observed observe VBN cord-288072-42sx52tn 129 14 in in IN cord-288072-42sx52tn 129 15 the the DT cord-288072-42sx52tn 129 16 commu- commu- JJ cord-288072-42sx52tn 129 17 Table Table NNP cord-288072-42sx52tn 129 18 3 3 CD cord-288072-42sx52tn 129 19 . . . cord-288072-42sx52tn 130 1 Age age NN cord-288072-42sx52tn 130 2 - - HYPH cord-288072-42sx52tn 130 3 specific specific JJ cord-288072-42sx52tn 130 4 occurrence occurrence NN cord-288072-42sx52tn 130 5 of of IN cord-288072-42sx52tn 130 6 infection infection NN cord-288072-42sx52tn 130 7 with with IN cord-288072-42sx52tn 130 8 coronavitus coronavitus NNP cord-288072-42sx52tn 130 9 OC43 OC43 NNP cord-288072-42sx52tn 130 10 during during IN cord-288072-42sx52tn 130 11 1968 1968 CD cord-288072-42sx52tn 130 12 - - SYM cord-288072-42sx52tn 130 13 1969 1969 CD cord-288072-42sx52tn 130 14 as as IN cord-288072-42sx52tn 130 15 determined determine VBN cord-288072-42sx52tn 130 16 by by IN cord-288072-42sx52tn 130 17 CF CF NNP cord-288072-42sx52tn 130 18 and and CC cord-288072-42sx52tn 130 19 HAl hal JJ cord-288072-42sx52tn 130 20 tests test NNS cord-288072-42sx52tn 130 21 . . . cord-288072-42sx52tn 131 1 * * NFP cord-288072-42sx52tn 131 2 Number number NN cord-288072-42sx52tn 131 3 of of IN cord-288072-42sx52tn 131 4 persons person NNS cord-288072-42sx52tn 131 5 with with IN cord-288072-42sx52tn 131 6 rise rise NN cord-288072-42sx52tn 131 7 in in IN cord-288072-42sx52tn 131 8 antibody antibody NN cord-288072-42sx52tn 131 9 titer titer NN cord-288072-42sx52tn 131 10 by by IN cord-288072-42sx52tn 131 11 CF CF NNP cord-288072-42sx52tn 131 12 alone alone RB cord-288072-42sx52tn 131 13 , , , cord-288072-42sx52tn 131 14 HAl HAl NNP cord-288072-42sx52tn 131 15 alone alone RB cord-288072-42sx52tn 131 16 , , , cord-288072-42sx52tn 131 17 or or CC cord-288072-42sx52tn 131 18 both both CC cord-288072-42sx52tn 131 19 CF CF NNP cord-288072-42sx52tn 131 20 and and CC cord-288072-42sx52tn 131 21 HAl HAl NNP cord-288072-42sx52tn 131 22 . . . cord-288072-42sx52tn 132 1 nity nity NN cord-288072-42sx52tn 132 2 during during IN cord-288072-42sx52tn 132 3 the the DT cord-288072-42sx52tn 132 4 229E 229e CD cord-288072-42sx52tn 132 5 outbreak outbreak NN cord-288072-42sx52tn 132 6 of of IN cord-288072-42sx52tn 132 7 1967 1967 CD cord-288072-42sx52tn 132 8 [ [ -LRB- cord-288072-42sx52tn 132 9 11 11 CD cord-288072-42sx52tn 132 10 ] ] -RRB- cord-288072-42sx52tn 132 11 . . . cord-288072-42sx52tn 133 1 Howevert howevert RB cord-288072-42sx52tn 133 2 the the DT cord-288072-42sx52tn 133 3 marked marked JJ cord-288072-42sx52tn 133 4 involvement involvement NN cord-288072-42sx52tn 133 5 of of IN cord-288072-42sx52tn 133 6 children child NNS cord-288072-42sx52tn 133 7 under under IN cord-288072-42sx52tn 133 8 age age NN cord-288072-42sx52tn 133 9 five five CD cord-288072-42sx52tn 133 10 was be VBD cord-288072-42sx52tn 133 11 not not RB cord-288072-42sx52tn 133 12 noted note VBN cord-288072-42sx52tn 133 13 at at IN cord-288072-42sx52tn 133 14 that that DT cord-288072-42sx52tn 133 15 time time NN cord-288072-42sx52tn 133 16 nor nor CC cord-288072-42sx52tn 133 17 has have VBZ cord-288072-42sx52tn 133 18 it -PRON- PRP cord-288072-42sx52tn 133 19 been be VBN cord-288072-42sx52tn 133 20 appreciated appreciate VBN cord-288072-42sx52tn 133 21 in in IN cord-288072-42sx52tn 133 22 other other JJ cord-288072-42sx52tn 133 23 studies study NNS cord-288072-42sx52tn 133 24 of of IN cord-288072-42sx52tn 133 25 coronavirus coronavirus NN cord-288072-42sx52tn 133 26 infections infection NNS cord-288072-42sx52tn 133 27 . . . cord-288072-42sx52tn 134 1 Relative relative JJ cord-288072-42sx52tn 134 2 frequency frequency NN cord-288072-42sx52tn 134 3 of of IN cord-288072-42sx52tn 134 4 CF cf NN cord-288072-42sx52tn 134 5 and and CC cord-288072-42sx52tn 134 6 HAl hal JJ cord-288072-42sx52tn 134 7 response response NN cord-288072-42sx52tn 134 8 among among IN cord-288072-42sx52tn 134 9 these these DT cord-288072-42sx52tn 134 10 small small JJ cord-288072-42sx52tn 134 11 children child NNS cord-288072-42sx52tn 134 12 was be VBD cord-288072-42sx52tn 134 13 like like IN cord-288072-42sx52tn 134 14 that that DT cord-288072-42sx52tn 134 15 of of IN cord-288072-42sx52tn 134 16 the the DT cord-288072-42sx52tn 134 17 rest rest NN cord-288072-42sx52tn 134 18 of of IN cord-288072-42sx52tn 134 19 the the DT cord-288072-42sx52tn 134 20 population population NN cord-288072-42sx52tn 134 21 during during IN cord-288072-42sx52tn 134 22 this this DT cord-288072-42sx52tn 134 23 period period NN cord-288072-42sx52tn 134 24 t t XX cord-288072-42sx52tn 134 25 with with IN cord-288072-42sx52tn 134 26 approximately approximately RB cord-288072-42sx52tn 134 27 two two CD cord-288072-42sx52tn 134 28 and and CC cord-288072-42sx52tn 134 29 a a DT cord-288072-42sx52tn 134 30 half half NN cord-288072-42sx52tn 134 31 times time NNS cord-288072-42sx52tn 134 32 as as IN cord-288072-42sx52tn 134 33 many many JJ cord-288072-42sx52tn 134 34 rises rise NNS cord-288072-42sx52tn 134 35 in in IN cord-288072-42sx52tn 134 36 titer titer NN cord-288072-42sx52tn 134 37 detected detect VBN cord-288072-42sx52tn 134 38 by by IN cord-288072-42sx52tn 134 39 HAl HAl NNS cord-288072-42sx52tn 134 40 compared compare VBN cord-288072-42sx52tn 134 41 with with IN cord-288072-42sx52tn 134 42 those those DT cord-288072-42sx52tn 134 43 detected detect VBN cord-288072-42sx52tn 134 44 by by IN cord-288072-42sx52tn 134 45 CF CF NNP cord-288072-42sx52tn 134 46 . . . cord-288072-42sx52tn 135 1 Familial familial JJ cord-288072-42sx52tn 135 2 aggregation aggregation NN cord-288072-42sx52tn 135 3 of of IN cord-288072-42sx52tn 135 4 infection infection NN cord-288072-42sx52tn 135 5 was be VBD cord-288072-42sx52tn 135 6 frequent frequent JJ cord-288072-42sx52tn 135 7 , , , cord-288072-42sx52tn 135 8 as as IN cord-288072-42sx52tn 135 9 has have VBZ cord-288072-42sx52tn 135 10 been be VBN cord-288072-42sx52tn 135 11 observed observe VBN cord-288072-42sx52tn 135 12 with with IN cord-288072-42sx52tn 135 13 other other JJ cord-288072-42sx52tn 135 14 respiratory respiratory JJ cord-288072-42sx52tn 135 15 viruses virus NNS cord-288072-42sx52tn 135 16 [ [ -LRB- cord-288072-42sx52tn 135 17 10 10 CD cord-288072-42sx52tn 135 18 ] ] -RRB- cord-288072-42sx52tn 135 19 . . . cord-288072-42sx52tn 136 1 As as RB cord-288072-42sx52tn 136 2 many many JJ cord-288072-42sx52tn 136 3 as as IN cord-288072-42sx52tn 136 4 four four CD cord-288072-42sx52tn 136 5 infections infection NNS cord-288072-42sx52tn 136 6 were be VBD cord-288072-42sx52tn 136 7 observed observe VBN cord-288072-42sx52tn 136 8 in in IN cord-288072-42sx52tn 136 9 a a DT cord-288072-42sx52tn 136 10 single single JJ cord-288072-42sx52tn 136 11 family family NN cord-288072-42sx52tn 136 12 . . . cord-288072-42sx52tn 137 1 During during IN cord-288072-42sx52tn 137 2 the the DT cord-288072-42sx52tn 137 3 229E 229e CD cord-288072-42sx52tn 137 4 outbreak outbreak NN cord-288072-42sx52tn 137 5 in in IN cord-288072-42sx52tn 137 6 1967 1967 CD cord-288072-42sx52tn 137 7 , , , cord-288072-42sx52tn 137 8 in in IN cord-288072-42sx52tn 137 9 spite spite NN cord-288072-42sx52tn 137 10 of of IN cord-288072-42sx52tn 137 11 the the DT cord-288072-42sx52tn 137 12 high high JJ cord-288072-42sx52tn 137 13 rate rate NN cord-288072-42sx52tn 137 14 of of IN cord-288072-42sx52tn 137 15 infection infection NN cord-288072-42sx52tn 137 16 and and CC cord-288072-42sx52tn 137 17 the the DT cord-288072-42sx52tn 137 18 fact fact NN cord-288072-42sx52tn 137 19 that that IN cord-288072-42sx52tn 137 20 infection infection NN cord-288072-42sx52tn 137 21 was be VBD cord-288072-42sx52tn 137 22 significantly significantly RB cord-288072-42sx52tn 137 23 associated associate VBN cord-288072-42sx52tn 137 24 with with IN cord-288072-42sx52tn 137 25 illness illness NN cord-288072-42sx52tn 137 26 , , , cord-288072-42sx52tn 137 27 no no DT cord-288072-42sx52tn 137 28 peak peak NN cord-288072-42sx52tn 137 29 in in IN cord-288072-42sx52tn 137 30 incidence incidence NN cord-288072-42sx52tn 137 31 of of IN cord-288072-42sx52tn 137 32 illness illness NN cord-288072-42sx52tn 137 33 could could MD cord-288072-42sx52tn 137 34 be be VB cord-288072-42sx52tn 137 35 identified identify VBN cord-288072-42sx52tn 137 36 [ [ -LRB- cord-288072-42sx52tn 137 37 11 11 CD cord-288072-42sx52tn 137 38 ] ] -RRB- cord-288072-42sx52tn 137 39 . . . cord-288072-42sx52tn 138 1 Similarly similarly RB cord-288072-42sx52tn 138 2 , , , cord-288072-42sx52tn 138 3 in in IN cord-288072-42sx52tn 138 4 the the DT cord-288072-42sx52tn 138 5 present present JJ cord-288072-42sx52tn 138 6 outbreak outbreak NN cord-288072-42sx52tn 138 7 no no DT cord-288072-42sx52tn 138 8 peak peak NN cord-288072-42sx52tn 138 9 of of IN cord-288072-42sx52tn 138 10 incidence incidence NN cord-288072-42sx52tn 138 11 of of IN cord-288072-42sx52tn 138 12 illness illness NN cord-288072-42sx52tn 138 13 could could MD cord-288072-42sx52tn 138 14 be be VB cord-288072-42sx52tn 138 15 identified identify VBN cord-288072-42sx52tn 138 16 in in IN cord-288072-42sx52tn 138 17 February February NNP cord-288072-42sx52tn 138 18 or or CC cord-288072-42sx52tn 138 19 March March NNP cord-288072-42sx52tn 138 20 1969 1969 CD cord-288072-42sx52tn 138 21 , , , cord-288072-42sx52tn 138 22 the the DT cord-288072-42sx52tn 138 23 likely likely JJ cord-288072-42sx52tn 138 24 period period NN cord-288072-42sx52tn 138 25 of of IN cord-288072-42sx52tn 138 26 peak peak NN cord-288072-42sx52tn 138 27 dissemination dissemination NN cord-288072-42sx52tn 138 28 of of IN cord-288072-42sx52tn 138 29 virus virus NN cord-288072-42sx52tn 138 30 . . . cord-288072-42sx52tn 139 1 Investigations investigation NNS cord-288072-42sx52tn 139 2 on on IN cord-288072-42sx52tn 139 3 the the DT cord-288072-42sx52tn 139 4 behavior behavior NN cord-288072-42sx52tn 139 5 in in IN cord-288072-42sx52tn 139 6 populations population NNS cord-288072-42sx52tn 139 7 of of IN cord-288072-42sx52tn 139 8 respiratory respiratory JJ cord-288072-42sx52tn 139 9 pathogens pathogen NNS cord-288072-42sx52tn 139 10 ideally ideally RB cord-288072-42sx52tn 139 11 use use VBP cord-288072-42sx52tn 139 12 as as IN cord-288072-42sx52tn 139 13 methods method NNS cord-288072-42sx52tn 139 14 both both DT cord-288072-42sx52tn 139 15 isolation isolation NN cord-288072-42sx52tn 139 16 of of IN cord-288072-42sx52tn 139 17 infecting infect VBG cord-288072-42sx52tn 139 18 viruses virus NNS cord-288072-42sx52tn 139 19 and and CC cord-288072-42sx52tn 139 20 testing testing NN cord-288072-42sx52tn 139 21 of of IN cord-288072-42sx52tn 139 22 sera sera NNP cord-288072-42sx52tn 139 23 . . . cord-288072-42sx52tn 140 1 An an DT cord-288072-42sx52tn 140 2 isolate isolate NN cord-288072-42sx52tn 140 3 can can MD cord-288072-42sx52tn 140 4 be be VB cord-288072-42sx52tn 140 5 used use VBN cord-288072-42sx52tn 140 6 as as IN cord-288072-42sx52tn 140 7 antigen antigen NN cord-288072-42sx52tn 140 8 in in IN cord-288072-42sx52tn 140 9 the the DT cord-288072-42sx52tn 140 10 serologic serologic JJ cord-288072-42sx52tn 140 11 procedures procedure NNS cord-288072-42sx52tn 140 12 and and CC cord-288072-42sx52tn 140 13 rises rise NNS cord-288072-42sx52tn 140 14 in in IN cord-288072-42sx52tn 140 15 antibody antibody NN cord-288072-42sx52tn 140 16 titer titer NN cord-288072-42sx52tn 140 17 related relate VBN cord-288072-42sx52tn 140 18 directly directly RB cord-288072-42sx52tn 140 19 to to IN cord-288072-42sx52tn 140 20 the the DT cord-288072-42sx52tn 140 21 activity activity NN cord-288072-42sx52tn 140 22 of of IN cord-288072-42sx52tn 140 23 that that DT cord-288072-42sx52tn 140 24 virus virus NN cord-288072-42sx52tn 140 25 . . . cord-288072-42sx52tn 141 1 Unfortunately unfortunately RB cord-288072-42sx52tn 141 2 , , , cord-288072-42sx52tn 141 3 with with IN cord-288072-42sx52tn 141 4 most most JJS cord-288072-42sx52tn 141 5 of of IN cord-288072-42sx52tn 141 6 the the DT cord-288072-42sx52tn 141 7 coronaviruses coronaviruse NNS cord-288072-42sx52tn 141 8 isolation isolation NN cord-288072-42sx52tn 141 9 is be VBZ cord-288072-42sx52tn 141 10 difficult difficult JJ cord-288072-42sx52tn 141 11 [ [ -LRB- cord-288072-42sx52tn 141 12 14 14 CD cord-288072-42sx52tn 141 13 , , , cord-288072-42sx52tn 141 14 15 15 CD cord-288072-42sx52tn 141 15 ] ] -RRB- cord-288072-42sx52tn 141 16 . . . cord-288072-42sx52tn 142 1 Seroepidemiology seroepidemiology NN cord-288072-42sx52tn 142 2 is be VBZ cord-288072-42sx52tn 142 3 thus thus RB cord-288072-42sx52tn 142 4 the the DT cord-288072-42sx52tn 142 5 only only JJ cord-288072-42sx52tn 142 6 technique technique NN cord-288072-42sx52tn 142 7 available available JJ cord-288072-42sx52tn 142 8 for for IN cord-288072-42sx52tn 142 9 study study NN cord-288072-42sx52tn 142 10 of of IN cord-288072-42sx52tn 142 11 infections infection NNS cord-288072-42sx52tn 142 12 caused cause VBN cord-288072-42sx52tn 142 13 by by IN cord-288072-42sx52tn 142 14 these these DT cord-288072-42sx52tn 142 15 agents agent NNS cord-288072-42sx52tn 142 16 in in IN cord-288072-42sx52tn 142 17 large large JJ cord-288072-42sx52tn 142 18 numbers number NNS cord-288072-42sx52tn 142 19 of of IN cord-288072-42sx52tn 142 20 people people NNS cord-288072-42sx52tn 142 21 . . . cord-288072-42sx52tn 143 1 The the DT cord-288072-42sx52tn 143 2 relation relation NN cord-288072-42sx52tn 143 3 between between IN cord-288072-42sx52tn 143 4 the the DT cord-288072-42sx52tn 143 5 virus virus NN cord-288072-42sx52tn 143 6 chosen choose VBN cord-288072-42sx52tn 143 7 for for IN cord-288072-42sx52tn 143 8 antigen antigen NN cord-288072-42sx52tn 143 9 and and CC cord-288072-42sx52tn 143 10 the the DT cord-288072-42sx52tn 143 11 virus virus NN cord-288072-42sx52tn 143 12 actually actually RB cord-288072-42sx52tn 143 13 infecting infect VBG cord-288072-42sx52tn 143 14 the the DT cord-288072-42sx52tn 143 15 population population NN cord-288072-42sx52tn 143 16 can can MD cord-288072-42sx52tn 143 17 thus thus RB cord-288072-42sx52tn 143 18 be be VB cord-288072-42sx52tn 143 19 determined determine VBN cord-288072-42sx52tn 143 20 only only RB cord-288072-42sx52tn 143 21 by by IN cord-288072-42sx52tn 143 22 inference inference NN cord-288072-42sx52tn 143 23 . . . cord-288072-42sx52tn 144 1 It -PRON- PRP cord-288072-42sx52tn 144 2 is be VBZ cord-288072-42sx52tn 144 3 known know VBN cord-288072-42sx52tn 144 4 that that IN cord-288072-42sx52tn 144 5 rises rise NNS cord-288072-42sx52tn 144 6 in in IN cord-288072-42sx52tn 144 7 titer titer NN cord-288072-42sx52tn 144 8 of of IN cord-288072-42sx52tn 144 9 heterologous heterologous NNP cord-288072-42sx52tn 144 10 antibody antibody NN cord-288072-42sx52tn 144 11 do do VBP cord-288072-42sx52tn 144 12 occur occur VB cord-288072-42sx52tn 144 13 [ [ -LRB- cord-288072-42sx52tn 144 14 16 16 CD cord-288072-42sx52tn 144 15 ] ] -RRB- cord-288072-42sx52tn 145 1 [ [ -LRB- cord-288072-42sx52tn 145 2 17 17 CD cord-288072-42sx52tn 145 3 ] ] -RRB- cord-288072-42sx52tn 145 4 [ [ -LRB- cord-288072-42sx52tn 145 5 18 18 CD cord-288072-42sx52tn 145 6 ] ] -RRB- cord-288072-42sx52tn 145 7 ; ; : cord-288072-42sx52tn 145 8 however however RB cord-288072-42sx52tn 145 9 , , , cord-288072-42sx52tn 145 10 the the DT cord-288072-42sx52tn 145 11 exact exact JJ cord-288072-42sx52tn 145 12 nature nature NN cord-288072-42sx52tn 145 13 and and CC cord-288072-42sx52tn 145 14 frequency frequency NN cord-288072-42sx52tn 145 15 of of IN cord-288072-42sx52tn 145 16 these these DT cord-288072-42sx52tn 145 17 cross cross NN cord-288072-42sx52tn 145 18 - - NNS cord-288072-42sx52tn 145 19 reactions reaction NNS cord-288072-42sx52tn 145 20 have have VBP cord-288072-42sx52tn 145 21 not not RB cord-288072-42sx52tn 145 22 been be VBN cord-288072-42sx52tn 145 23 determined determine VBN cord-288072-42sx52tn 145 24 . . . cord-288072-42sx52tn 146 1 Only only RB cord-288072-42sx52tn 146 2 limited limited JJ cord-288072-42sx52tn 146 3 numbers number NNS cord-288072-42sx52tn 146 4 of of IN cord-288072-42sx52tn 146 5 natural natural JJ cord-288072-42sx52tn 146 6 infections infection NNS cord-288072-42sx52tn 146 7 have have VBP cord-288072-42sx52tn 146 8 been be VBN cord-288072-42sx52tn 146 9 studied study VBN cord-288072-42sx52tn 146 10 by by IN cord-288072-42sx52tn 146 11 both both DT cord-288072-42sx52tn 146 12 isolation isolation NN cord-288072-42sx52tn 146 13 and and CC cord-288072-42sx52tn 146 14 serology serology NN cord-288072-42sx52tn 146 15 , , , cord-288072-42sx52tn 146 16 a a DT cord-288072-42sx52tn 146 17 situation situation NN cord-288072-42sx52tn 146 18 in in IN cord-288072-42sx52tn 146 19 which which WDT cord-288072-42sx52tn 146 20 the the DT cord-288072-42sx52tn 146 21 critical critical JJ cord-288072-42sx52tn 146 22 observations observation NNS cord-288072-42sx52tn 146 23 on on IN cord-288072-42sx52tn 146 24 antibody antibody NN cord-288072-42sx52tn 146 25 response response NN cord-288072-42sx52tn 146 26 should should MD cord-288072-42sx52tn 146 27 be be VB cord-288072-42sx52tn 146 28 possible possible JJ cord-288072-42sx52tn 146 29 ; ; : cord-288072-42sx52tn 146 30 thus thus RB cord-288072-42sx52tn 146 31 basic basic JJ cord-288072-42sx52tn 146 32 gaps gap NNS cord-288072-42sx52tn 146 33 in in IN cord-288072-42sx52tn 146 34 essential essential JJ cord-288072-42sx52tn 146 35 knowledge knowledge NN cord-288072-42sx52tn 146 36 exist exist VBP cord-288072-42sx52tn 146 37 . . . cord-288072-42sx52tn 147 1 Use use NN cord-288072-42sx52tn 147 2 of of IN cord-288072-42sx52tn 147 3 parallel parallel JJ cord-288072-42sx52tn 147 4 CF cf NN cord-288072-42sx52tn 147 5 and and CC cord-288072-42sx52tn 147 6 HAl hal JJ cord-288072-42sx52tn 147 7 procedures procedure NNS cord-288072-42sx52tn 147 8 was be VBD cord-288072-42sx52tn 147 9 based base VBN cord-288072-42sx52tn 147 10 on on IN cord-288072-42sx52tn 147 11 the the DT cord-288072-42sx52tn 147 12 possibility possibility NN cord-288072-42sx52tn 147 13 that that IN cord-288072-42sx52tn 147 14 heterologous heterologous JJ cord-288072-42sx52tn 147 15 crossreactions crossreaction NNS cord-288072-42sx52tn 147 16 might may MD cord-288072-42sx52tn 147 17 be be VB cord-288072-42sx52tn 147 18 encountered encounter VBN cord-288072-42sx52tn 147 19 ; ; : cord-288072-42sx52tn 147 20 it -PRON- PRP cord-288072-42sx52tn 147 21 seemed seem VBD cord-288072-42sx52tn 147 22 more more RBR cord-288072-42sx52tn 147 23 likely likely JJ cord-288072-42sx52tn 147 24 that that IN cord-288072-42sx52tn 147 25 there there EX cord-288072-42sx52tn 147 26 would would MD cord-288072-42sx52tn 147 27 be be VB cord-288072-42sx52tn 147 28 agreement agreement NN cord-288072-42sx52tn 147 29 between between IN cord-288072-42sx52tn 147 30 the the DT cord-288072-42sx52tn 147 31 two two CD cord-288072-42sx52tn 147 32 tests test NNS cord-288072-42sx52tn 147 33 when when WRB cord-288072-42sx52tn 147 34 the the DT cord-288072-42sx52tn 147 35 infecting infect VBG cord-288072-42sx52tn 147 36 organism organism NN cord-288072-42sx52tn 147 37 was be VBD cord-288072-42sx52tn 147 38 closely closely RB cord-288072-42sx52tn 147 39 related relate VBN cord-288072-42sx52tn 147 40 to to IN cord-288072-42sx52tn 147 41 OC43 OC43 NNP cord-288072-42sx52tn 147 42 . . . cord-288072-42sx52tn 148 1 Disagreement disagreement NN cord-288072-42sx52tn 148 2 could could MD cord-288072-42sx52tn 148 3 be be VB cord-288072-42sx52tn 148 4 a a DT cord-288072-42sx52tn 148 5 result result NN cord-288072-42sx52tn 148 6 275 275 CD cord-288072-42sx52tn 148 7 of of IN cord-288072-42sx52tn 148 8 either either DT cord-288072-42sx52tn 148 9 lack lack NN cord-288072-42sx52tn 148 10 of of IN cord-288072-42sx52tn 148 11 close close JJ cord-288072-42sx52tn 148 12 relation relation NN cord-288072-42sx52tn 148 13 between between IN cord-288072-42sx52tn 148 14 the the DT cord-288072-42sx52tn 148 15 infecting infect VBG cord-288072-42sx52tn 148 16 organism organism NN cord-288072-42sx52tn 148 17 and and CC cord-288072-42sx52tn 148 18 OC43 OC43 NNP cord-288072-42sx52tn 148 19 or or CC cord-288072-42sx52tn 148 20 the the DT cord-288072-42sx52tn 148 21 fact fact NN cord-288072-42sx52tn 148 22 that that IN cord-288072-42sx52tn 148 23 one one CD cord-288072-42sx52tn 148 24 of of IN cord-288072-42sx52tn 148 25 the the DT cord-288072-42sx52tn 148 26 serologic serologic NNP cord-288072-42sx52tn 148 27 tests test NNS cord-288072-42sx52tn 148 28 was be VBD cord-288072-42sx52tn 148 29 more more RBR cord-288072-42sx52tn 148 30 sensitive sensitive JJ cord-288072-42sx52tn 148 31 than than IN cord-288072-42sx52tn 148 32 the the DT cord-288072-42sx52tn 148 33 other other JJ cord-288072-42sx52tn 148 34 . . . cord-288072-42sx52tn 149 1 However however RB cord-288072-42sx52tn 149 2 , , , cord-288072-42sx52tn 149 3 in in IN cord-288072-42sx52tn 149 4 terms term NNS cord-288072-42sx52tn 149 5 of of IN cord-288072-42sx52tn 149 6 differences difference NNS cord-288072-42sx52tn 149 7 in in IN cord-288072-42sx52tn 149 8 agreement agreement NN cord-288072-42sx52tn 149 9 from from IN cord-288072-42sx52tn 149 10 year year NN cord-288072-42sx52tn 149 11 to to IN cord-288072-42sx52tn 149 12 year year NN cord-288072-42sx52tn 149 13 , , , cord-288072-42sx52tn 149 14 the the DT cord-288072-42sx52tn 149 15 former former JJ cord-288072-42sx52tn 149 16 factor factor NN cord-288072-42sx52tn 149 17 was be VBD cord-288072-42sx52tn 149 18 operative operative JJ cord-288072-42sx52tn 149 19 . . . cord-288072-42sx52tn 150 1 The the DT cord-288072-42sx52tn 150 2 viruses virus NNS cord-288072-42sx52tn 150 3 in in IN cord-288072-42sx52tn 150 4 circulation circulation NN cord-288072-42sx52tn 150 5 in in IN cord-288072-42sx52tn 150 6 1966 1966 CD cord-288072-42sx52tn 150 7 and and CC cord-288072-42sx52tn 150 8 1969 1969 CD cord-288072-42sx52tn 150 9 were be VBD cord-288072-42sx52tn 150 10 clearly clearly RB cord-288072-42sx52tn 150 11 more more RBR cord-288072-42sx52tn 150 12 closely closely RB cord-288072-42sx52tn 150 13 related related JJ cord-288072-42sx52tn 150 14 to to IN cord-288072-42sx52tn 150 15 OC43 OC43 NNP cord-288072-42sx52tn 150 16 than than IN cord-288072-42sx52tn 150 17 those those DT cord-288072-42sx52tn 150 18 in in IN cord-288072-42sx52tn 150 19 circulation circulation NN cord-288072-42sx52tn 150 20 in in IN cord-288072-42sx52tn 150 21 1968 1968 CD cord-288072-42sx52tn 150 22 , , , cord-288072-42sx52tn 150 23 a a DT cord-288072-42sx52tn 150 24 difference difference NN cord-288072-42sx52tn 150 25 that that WDT cord-288072-42sx52tn 150 26 would would MD cord-288072-42sx52tn 150 27 not not RB cord-288072-42sx52tn 150 28 have have VB cord-288072-42sx52tn 150 29 been be VBN cord-288072-42sx52tn 150 30 detected detect VBN cord-288072-42sx52tn 150 31 had have VBN cord-288072-42sx52tn 150 32 both both CC cord-288072-42sx52tn 150 33 CF CF NNP cord-288072-42sx52tn 150 34 and and CC cord-288072-42sx52tn 150 35 HAl HAl NNP cord-288072-42sx52tn 150 36 not not RB cord-288072-42sx52tn 150 37 been be VBN cord-288072-42sx52tn 150 38 used use VBN cord-288072-42sx52tn 150 39 . . . cord-288072-42sx52tn 151 1 Neutralization neutralization NN cord-288072-42sx52tn 151 2 tests test NNS cord-288072-42sx52tn 151 3 confirmed confirm VBD cord-288072-42sx52tn 151 4 the the DT cord-288072-42sx52tn 151 5 difference difference NN cord-288072-42sx52tn 151 6 , , , cord-288072-42sx52tn 151 7 and and CC cord-288072-42sx52tn 151 8 indicated indicate VBD cord-288072-42sx52tn 151 9 that that IN cord-288072-42sx52tn 151 10 in in IN cord-288072-42sx52tn 151 11 the the DT cord-288072-42sx52tn 151 12 individual individual JJ cord-288072-42sx52tn 151 13 case case NN cord-288072-42sx52tn 151 14 during during IN cord-288072-42sx52tn 151 15 a a DT cord-288072-42sx52tn 151 16 period period NN cord-288072-42sx52tn 151 17 of of IN cord-288072-42sx52tn 151 18 prevalence prevalence NN cord-288072-42sx52tn 151 19 of of IN cord-288072-42sx52tn 151 20 agents agent NNS cord-288072-42sx52tn 151 21 related relate VBN cord-288072-42sx52tn 151 22 to to IN cord-288072-42sx52tn 151 23 OC43 OC43 NNP cord-288072-42sx52tn 151 24 , , , cord-288072-42sx52tn 151 25 even even RB cord-288072-42sx52tn 151 26 if if IN cord-288072-42sx52tn 151 27 CF CF NNP cord-288072-42sx52tn 151 28 and and CC cord-288072-42sx52tn 151 29 HAl HAl NNPS cord-288072-42sx52tn 151 30 do do VBP cord-288072-42sx52tn 151 31 not not RB cord-288072-42sx52tn 151 32 agree agree VB cord-288072-42sx52tn 151 33 , , , cord-288072-42sx52tn 151 34 it -PRON- PRP cord-288072-42sx52tn 151 35 is be VBZ cord-288072-42sx52tn 151 36 likely likely JJ cord-288072-42sx52tn 151 37 that that IN cord-288072-42sx52tn 151 38 an an DT cord-288072-42sx52tn 151 39 infection infection NN cord-288072-42sx52tn 151 40 with with IN cord-288072-42sx52tn 151 41 the the DT cord-288072-42sx52tn 151 42 agent agent NN cord-288072-42sx52tn 151 43 actually actually RB cord-288072-42sx52tn 151 44 did do VBD cord-288072-42sx52tn 151 45 occur occur VB cord-288072-42sx52tn 151 46 . . . cord-288072-42sx52tn 152 1 It -PRON- PRP cord-288072-42sx52tn 152 2 may may MD cord-288072-42sx52tn 152 3 also also RB cord-288072-42sx52tn 152 4 be be VB cord-288072-42sx52tn 152 5 speculated speculate VBN cord-288072-42sx52tn 152 6 that that IN cord-288072-42sx52tn 152 7 some some DT cord-288072-42sx52tn 152 8 minor minor JJ cord-288072-42sx52tn 152 9 differences difference NNS cord-288072-42sx52tn 152 10 existed exist VBD cord-288072-42sx52tn 152 11 between between IN cord-288072-42sx52tn 152 12 the the DT cord-288072-42sx52tn 152 13 1966 1966 CD cord-288072-42sx52tn 152 14 and and CC cord-288072-42sx52tn 152 15 1969 1969 CD cord-288072-42sx52tn 152 16 viruses virus NNS cord-288072-42sx52tn 152 17 , , , cord-288072-42sx52tn 152 18 since since IN cord-288072-42sx52tn 152 19 CF CF NNP cord-288072-42sx52tn 152 20 was be VBD cord-288072-42sx52tn 152 21 more more RBR cord-288072-42sx52tn 152 22 frequently frequently RB cord-288072-42sx52tn 152 23 positive positive JJ cord-288072-42sx52tn 152 24 in in IN cord-288072-42sx52tn 152 25 the the DT cord-288072-42sx52tn 152 26 former former JJ cord-288072-42sx52tn 152 27 period period NN cord-288072-42sx52tn 152 28 and and CC cord-288072-42sx52tn 152 29 HAl HAl NNS cord-288072-42sx52tn 152 30 in in IN cord-288072-42sx52tn 152 31 the the DT cord-288072-42sx52tn 152 32 latter latter JJ cord-288072-42sx52tn 152 33 . . . cord-288072-42sx52tn 153 1 The the DT cord-288072-42sx52tn 153 2 annual annual JJ cord-288072-42sx52tn 153 3 periodic periodic JJ cord-288072-42sx52tn 153 4 pattern pattern NN cord-288072-42sx52tn 153 5 of of IN cord-288072-42sx52tn 153 6 coronavirus coronavirus NN cord-288072-42sx52tn 153 7 infections infection NNS cord-288072-42sx52tn 153 8 in in IN cord-288072-42sx52tn 153 9 general general JJ cord-288072-42sx52tn 153 10 is be VBZ cord-288072-42sx52tn 153 11 clear clear JJ cord-288072-42sx52tn 153 12 from from IN cord-288072-42sx52tn 153 13 the the DT cord-288072-42sx52tn 153 14 Tecumseh Tecumseh NNP cord-288072-42sx52tn 153 15 data datum NNS cord-288072-42sx52tn 153 16 when when WRB cord-288072-42sx52tn 153 17 the the DT cord-288072-42sx52tn 153 18 1967 1967 CD cord-288072-42sx52tn 153 19 229E 229e CD cord-288072-42sx52tn 153 20 outbreak outbreak NN cord-288072-42sx52tn 153 21 is be VBZ cord-288072-42sx52tn 153 22 included include VBN cord-288072-42sx52tn 153 23 , , , cord-288072-42sx52tn 153 24 and and CC cord-288072-42sx52tn 153 25 is be VBZ cord-288072-42sx52tn 153 26 in in IN cord-288072-42sx52tn 153 27 agreement agreement NN cord-288072-42sx52tn 153 28 with with IN cord-288072-42sx52tn 153 29 the the DT cord-288072-42sx52tn 153 30 findings finding NNS cord-288072-42sx52tn 153 31 of of IN cord-288072-42sx52tn 153 32 others other NNS cord-288072-42sx52tn 153 33 [ [ -LRB- cord-288072-42sx52tn 153 34 2 2 CD cord-288072-42sx52tn 153 35 , , , cord-288072-42sx52tn 153 36 3 3 CD cord-288072-42sx52tn 153 37 , , , cord-288072-42sx52tn 153 38 8 8 CD cord-288072-42sx52tn 153 39 ] ] -RRB- cord-288072-42sx52tn 153 40 . . . cord-288072-42sx52tn 154 1 The the DT cord-288072-42sx52tn 154 2 outbreaks outbreak NNS cord-288072-42sx52tn 154 3 take take VBP cord-288072-42sx52tn 154 4 place place NN cord-288072-42sx52tn 154 5 in in IN cord-288072-42sx52tn 154 6 the the DT cord-288072-42sx52tn 154 7 period period NN cord-288072-42sx52tn 154 8 of of IN cord-288072-42sx52tn 154 9 late late JJ cord-288072-42sx52tn 154 10 winter winter NN cord-288072-42sx52tn 154 11 through through IN cord-288072-42sx52tn 154 12 early early JJ cord-288072-42sx52tn 154 13 spring spring NN cord-288072-42sx52tn 154 14 , , , cord-288072-42sx52tn 154 15 with with IN cord-288072-42sx52tn 154 16 sporadic sporadic JJ cord-288072-42sx52tn 154 17 infections infection NNS cord-288072-42sx52tn 154 18 at at IN cord-288072-42sx52tn 154 19 other other JJ cord-288072-42sx52tn 154 20 times time NNS cord-288072-42sx52tn 154 21 of of IN cord-288072-42sx52tn 154 22 the the DT cord-288072-42sx52tn 154 23 year year NN cord-288072-42sx52tn 154 24 . . . cord-288072-42sx52tn 155 1 A a DT cord-288072-42sx52tn 155 2 longer long JJR cord-288072-42sx52tn 155 3 cycle cycle NN cord-288072-42sx52tn 155 4 for for IN cord-288072-42sx52tn 155 5 a a DT cord-288072-42sx52tn 155 6 specific specific JJ cord-288072-42sx52tn 155 7 virus virus NN cord-288072-42sx52tn 155 8 type type NN cord-288072-42sx52tn 155 9 can can MD cord-288072-42sx52tn 155 10 also also RB cord-288072-42sx52tn 155 11 be be VB cord-288072-42sx52tn 155 12 deduced deduce VBN cord-288072-42sx52tn 155 13 from from IN cord-288072-42sx52tn 155 14 the the DT cord-288072-42sx52tn 155 15 data datum NNS cord-288072-42sx52tn 155 16 . . . cord-288072-42sx52tn 156 1 The the DT cord-288072-42sx52tn 156 2 period period NN cord-288072-42sx52tn 156 3 between between IN cord-288072-42sx52tn 156 4 the the DT cord-288072-42sx52tn 156 5 OC43-like OC43-like NNP cord-288072-42sx52tn 156 6 outbreaks outbreak NNS cord-288072-42sx52tn 156 7 was be VBD cord-288072-42sx52tn 156 8 three three CD cord-288072-42sx52tn 156 9 years year NNS cord-288072-42sx52tn 156 10 . . . cord-288072-42sx52tn 157 1 Periods period NNS cord-288072-42sx52tn 157 2 of of IN cord-288072-42sx52tn 157 3 high high JJ cord-288072-42sx52tn 157 4 incidence incidence NN cord-288072-42sx52tn 157 5 of of IN cord-288072-42sx52tn 157 6 229E 229e CD cord-288072-42sx52tn 157 7 infections infection NNS cord-288072-42sx52tn 157 8 have have VBP cord-288072-42sx52tn 157 9 also also RB cord-288072-42sx52tn 157 10 been be VBN cord-288072-42sx52tn 157 11 reported report VBN cord-288072-42sx52tn 157 12 to to TO cord-288072-42sx52tn 157 13 recur recur VB cord-288072-42sx52tn 157 14 on on IN cord-288072-42sx52tn 157 15 a a DT cord-288072-42sx52tn 157 16 two two CD cord-288072-42sx52tn 157 17 - - HYPH cord-288072-42sx52tn 157 18 or or CC cord-288072-42sx52tn 157 19 three three CD cord-288072-42sx52tn 157 20 - - HYPH cord-288072-42sx52tn 157 21 year year NN cord-288072-42sx52tn 157 22 cycle cycle NN cord-288072-42sx52tn 157 23 [ [ -LRB- cord-288072-42sx52tn 157 24 19 19 CD cord-288072-42sx52tn 157 25 ] ] -RRB- cord-288072-42sx52tn 157 26 . . . cord-288072-42sx52tn 158 1 The the DT cord-288072-42sx52tn 158 2 repetitive repetitive JJ cord-288072-42sx52tn 158 3 activity activity NN cord-288072-42sx52tn 158 4 of of IN cord-288072-42sx52tn 158 5 specific specific JJ cord-288072-42sx52tn 158 6 coronaviruses coronaviruse NNS cord-288072-42sx52tn 158 7 and and CC cord-288072-42sx52tn 158 8 the the DT cord-288072-42sx52tn 158 9 fact fact NN cord-288072-42sx52tn 158 10 that that IN cord-288072-42sx52tn 158 11 they -PRON- PRP cord-288072-42sx52tn 158 12 cause cause VBP cord-288072-42sx52tn 158 13 large large JJ cord-288072-42sx52tn 158 14 - - HYPH cord-288072-42sx52tn 158 15 scale scale NN cord-288072-42sx52tn 158 16 outbreaks outbreak NNS cord-288072-42sx52tn 158 17 of of IN cord-288072-42sx52tn 158 18 infection infection NN cord-288072-42sx52tn 158 19 is be VBZ cord-288072-42sx52tn 158 20 in in IN cord-288072-42sx52tn 158 21 marked mark VBN cord-288072-42sx52tn 158 22 contrast contrast NN cord-288072-42sx52tn 158 23 to to IN cord-288072-42sx52tn 158 24 the the DT cord-288072-42sx52tn 158 25 situation situation NN cord-288072-42sx52tn 158 26 with with IN cord-288072-42sx52tn 158 27 the the DT cord-288072-42sx52tn 158 28 rhinoviruses rhinovirus NNS cord-288072-42sx52tn 158 29 . . . cord-288072-42sx52tn 159 1 Cycling cycle VBG cord-288072-42sx52tn 159 2 of of IN cord-288072-42sx52tn 159 3 these these DT cord-288072-42sx52tn 159 4 agents agent NNS cord-288072-42sx52tn 159 5 occurs occur VBZ cord-288072-42sx52tn 159 6 but but CC cord-288072-42sx52tn 159 7 not not RB cord-288072-42sx52tn 159 8 on on IN cord-288072-42sx52tn 159 9 any any DT cord-288072-42sx52tn 159 10 sort sort NN cord-288072-42sx52tn 159 11 of of IN cord-288072-42sx52tn 159 12 a a DT cord-288072-42sx52tn 159 13 regular regular JJ cord-288072-42sx52tn 159 14 or or CC cord-288072-42sx52tn 159 15 predictable predictable JJ cord-288072-42sx52tn 159 16 basis basis NN cord-288072-42sx52tn 159 17 . . . cord-288072-42sx52tn 160 1 However however RB cord-288072-42sx52tn 160 2 , , , cord-288072-42sx52tn 160 3 the the DT cord-288072-42sx52tn 160 4 number number NN cord-288072-42sx52tn 160 5 of of IN cord-288072-42sx52tn 160 6 infections infection NNS cord-288072-42sx52tn 160 7 caused cause VBN cord-288072-42sx52tn 160 8 at at IN cord-288072-42sx52tn 160 9 anyone anyone NN cord-288072-42sx52tn 160 10 time time NN cord-288072-42sx52tn 160 11 is be VBZ cord-288072-42sx52tn 160 12 low low JJ cord-288072-42sx52tn 160 13 , , , cord-288072-42sx52tn 160 14 and and CC cord-288072-42sx52tn 160 15 many many JJ cord-288072-42sx52tn 160 16 agents agent NNS cord-288072-42sx52tn 160 17 take take VBP cord-288072-42sx52tn 160 18 part part NN cord-288072-42sx52tn 160 19 in in IN cord-288072-42sx52tn 160 20 a a DT cord-288072-42sx52tn 160 21 single single JJ cord-288072-42sx52tn 160 22 peak peak NN cord-288072-42sx52tn 160 23 of of IN cord-288072-42sx52tn 160 24 illness illness NN cord-288072-42sx52tn 160 25 [ [ -LRB- cord-288072-42sx52tn 160 26 20 20 CD cord-288072-42sx52tn 160 27 ] ] -RRB- cord-288072-42sx52tn 160 28 . . . cord-288072-42sx52tn 161 1 The the DT cord-288072-42sx52tn 161 2 fact fact NN cord-288072-42sx52tn 161 3 that that IN cord-288072-42sx52tn 161 4 coronaviruses coronaviruse NNS cord-288072-42sx52tn 161 5 individually individually RB cord-288072-42sx52tn 161 6 seem seem VBP cord-288072-42sx52tn 161 7 to to TO cord-288072-42sx52tn 161 8 cycle cycle VB cord-288072-42sx52tn 161 9 more more RBR cord-288072-42sx52tn 161 10 regularly regularly RB cord-288072-42sx52tn 161 11 and and CC cord-288072-42sx52tn 161 12 cause cause VB cord-288072-42sx52tn 161 13 many many JJ cord-288072-42sx52tn 161 14 infections infection NNS cord-288072-42sx52tn 161 15 suggests suggest VBZ cord-288072-42sx52tn 161 16 that that IN cord-288072-42sx52tn 161 17 there there EX cord-288072-42sx52tn 161 18 are be VBP cord-288072-42sx52tn 161 19 a a DT cord-288072-42sx52tn 161 20 reasonably reasonably RB cord-288072-42sx52tn 161 21 small small JJ cord-288072-42sx52tn 161 22 number number NN cord-288072-42sx52tn 161 23 of of IN cord-288072-42sx52tn 161 24 these these DT cord-288072-42sx52tn 161 25 agents agent NNS cord-288072-42sx52tn 161 26 in in IN cord-288072-42sx52tn 161 27 existence existence NN cord-288072-42sx52tn 161 28 . . . cord-288072-42sx52tn 162 1 This this DT cord-288072-42sx52tn 162 2 has have VBZ cord-288072-42sx52tn 162 3 positive positive JJ cord-288072-42sx52tn 162 4 implications implication NNS cord-288072-42sx52tn 162 5 in in IN cord-288072-42sx52tn 162 6 terms term NNS cord-288072-42sx52tn 162 7 of of IN cord-288072-42sx52tn 162 8 control control NN cord-288072-42sx52tn 162 9 . . . cord-288072-42sx52tn 163 1 However however RB cord-288072-42sx52tn 163 2 , , , cord-288072-42sx52tn 163 3 reinfection reinfection NN cord-288072-42sx52tn 163 4 with with IN cord-288072-42sx52tn 163 5 coronaviruses coronaviruse NNS cord-288072-42sx52tn 163 6 is be VBZ cord-288072-42sx52tn 163 7 a a DT cord-288072-42sx52tn 163 8 very very RB cord-288072-42sx52tn 163 9 frequent frequent JJ cord-288072-42sx52tn 163 10 event event NN cord-288072-42sx52tn 163 11 . . . cord-288072-42sx52tn 164 1 In in IN cord-288072-42sx52tn 164 2 the the DT cord-288072-42sx52tn 164 3 present present JJ cord-288072-42sx52tn 164 4 study study NN cord-288072-42sx52tn 164 5 , , , cord-288072-42sx52tn 164 6 81.5 81.5 CD cord-288072-42sx52tn 164 7 % % NN cord-288072-42sx52tn 164 8 of of IN cord-288072-42sx52tn 164 9 the the DT cord-288072-42sx52tn 164 10 infections infection NNS cord-288072-42sx52tn 164 11 studied study VBN cord-288072-42sx52tn 164 12 by by IN cord-288072-42sx52tn 164 13 the the DT cord-288072-42sx52tn 164 14 neutralization neutralization NN cord-288072-42sx52tn 164 15 tests test NNS cord-288072-42sx52tn 164 16 occurred occur VBD cord-288072-42sx52tn 164 17 despite despite IN cord-288072-42sx52tn 164 18 prior prior RB cord-288072-42sx52tn 164 19 neutralizing neutralize VBG cord-288072-42sx52tn 164 20 antibody antibody NN cord-288072-42sx52tn 164 21 . . . cord-288072-42sx52tn 165 1 Others other NNS cord-288072-42sx52tn 165 2 have have VBP cord-288072-42sx52tn 165 3 also also RB cord-288072-42sx52tn 165 4 noted note VBN cord-288072-42sx52tn 165 5 that that IN cord-288072-42sx52tn 165 6 antibody antibody NN cord-288072-42sx52tn 165 7 is be VBZ cord-288072-42sx52tn 165 8 usually usually RB cord-288072-42sx52tn 165 9 present present JJ cord-288072-42sx52tn 165 10 before before IN cord-288072-42sx52tn 165 11 a a DT cord-288072-42sx52tn 165 12 rise rise NN cord-288072-42sx52tn 165 13 in in IN cord-288072-42sx52tn 165 14 titer titer NN cord-288072-42sx52tn 165 15 and and CC cord-288072-42sx52tn 165 16 have have VBP cord-288072-42sx52tn 165 17 thus thus RB cord-288072-42sx52tn 165 18 called call VBN cord-288072-42sx52tn 165 19 into into IN cord-288072-42sx52tn 165 20 question question NN cord-288072-42sx52tn 165 21 the the DT cord-288072-42sx52tn 165 22 protective protective JJ cord-288072-42sx52tn 165 23 value value NN cord-288072-42sx52tn 165 24 of of IN cord-288072-42sx52tn 165 25 this this DT cord-288072-42sx52tn 165 26 circulating circulate VBG cord-288072-42sx52tn 165 27 neutralizing neutralize VBG cord-288072-42sx52tn 165 28 antibody antibody NN cord-288072-42sx52tn 165 29 [ [ -LRB- cord-288072-42sx52tn 165 30 9 9 CD cord-288072-42sx52tn 165 31 , , , cord-288072-42sx52tn 165 32 19 19 CD cord-288072-42sx52tn 165 33 ] ] -RRB- cord-288072-42sx52tn 165 34 . . . cord-288072-42sx52tn 166 1 The the DT cord-288072-42sx52tn 166 2 occurrence occurrence NN cord-288072-42sx52tn 166 3 of of IN cord-288072-42sx52tn 166 4 reinfections reinfection NNS cord-288072-42sx52tn 166 5 explains explain VBZ cord-288072-42sx52tn 166 6 , , , cord-288072-42sx52tn 166 7 in in IN cord-288072-42sx52tn 166 8 part part NN cord-288072-42sx52tn 166 9 , , , cord-288072-42sx52tn 166 10 the the DT cord-288072-42sx52tn 166 11 age age NN cord-288072-42sx52tn 166 12 - - HYPH cord-288072-42sx52tn 166 13 specific specific JJ cord-288072-42sx52tn 166 14 patterns pattern NNS cord-288072-42sx52tn 166 15 observed observe VBN cord-288072-42sx52tn 166 16 with with IN cord-288072-42sx52tn 166 17 OC43 OC43 NNP cord-288072-42sx52tn 166 18 infection infection NN cord-288072-42sx52tn 166 19 in in IN cord-288072-42sx52tn 166 20 Tecumseh Tecumseh NNP cord-288072-42sx52tn 166 21 . . . cord-288072-42sx52tn 167 1 Antibody antibody NN cord-288072-42sx52tn 167 2 is be VBZ cord-288072-42sx52tn 167 3 acquired acquire VBN cord-288072-42sx52tn 167 4 early early RB cord-288072-42sx52tn 167 5 in in IN cord-288072-42sx52tn 167 6 life life NN cord-288072-42sx52tn 167 7 , , , cord-288072-42sx52tn 167 8 as as IN cord-288072-42sx52tn 167 9 shown show VBN cord-288072-42sx52tn 167 10 by by IN cord-288072-42sx52tn 167 11 high high JJ cord-288072-42sx52tn 167 12 incidence incidence NN cord-288072-42sx52tn 167 13 of of IN cord-288072-42sx52tn 167 14 infection infection NN cord-288072-42sx52tn 167 15 in in IN cord-288072-42sx52tn 167 16 children child NNS cord-288072-42sx52tn 167 17 less less JJR cord-288072-42sx52tn 167 18 than than IN cord-288072-42sx52tn 167 19 five five CD cord-288072-42sx52tn 167 20 years year NNS cord-288072-42sx52tn 167 21 of of IN cord-288072-42sx52tn 167 22 age age NN cord-288072-42sx52tn 167 23 . . . cord-288072-42sx52tn 168 1 Subsequently subsequently RB cord-288072-42sx52tn 168 2 , , , cord-288072-42sx52tn 168 3 reinfection reinfection NN cord-288072-42sx52tn 168 4 is be VBZ cord-288072-42sx52tn 168 5 frequent frequent JJ cord-288072-42sx52tn 168 6 in in IN cord-288072-42sx52tn 168 7 older old JJR cord-288072-42sx52tn 168 8 children child NNS cord-288072-42sx52tn 168 9 and and CC cord-288072-42sx52tn 168 10 in in IN cord-288072-42sx52tn 168 11 adults adult NNS cord-288072-42sx52tn 168 12 . . . cord-288072-42sx52tn 169 1 This this DT cord-288072-42sx52tn 169 2 frequency frequency NN cord-288072-42sx52tn 169 3 of of IN cord-288072-42sx52tn 169 4 infection infection NN cord-288072-42sx52tn 169 5 in in IN cord-288072-42sx52tn 169 6 adults adult NNS cord-288072-42sx52tn 169 7 may may MD cord-288072-42sx52tn 169 8 explain explain VB cord-288072-42sx52tn 169 9 the the DT cord-288072-42sx52tn 169 10 relation relation NN cord-288072-42sx52tn 169 11 of of IN cord-288072-42sx52tn 169 12 coronaviruses coronaviruse NNS cord-288072-42sx52tn 169 13 to to IN cord-288072-42sx52tn 169 14 exacerbations exacerbation NNS cord-288072-42sx52tn 169 15 of of IN cord-288072-42sx52tn 169 16 chronic chronic JJ cord-288072-42sx52tn 169 17 bronchitis bronchitis NN cord-288072-42sx52tn 169 18 [ [ -LRB- cord-288072-42sx52tn 169 19 21 21 CD cord-288072-42sx52tn 169 20 ] ] -RRB- cord-288072-42sx52tn 169 21 . . . cord-288072-42sx52tn 170 1 The the DT cord-288072-42sx52tn 170 2 proportion proportion NN cord-288072-42sx52tn 170 3 of of IN cord-288072-42sx52tn 170 4 the the DT cord-288072-42sx52tn 170 5 OC43 OC43 NNP cord-288072-42sx52tn 170 6 infections infection NNS cord-288072-42sx52tn 170 7 detected detect VBD cord-288072-42sx52tn 170 8 serologically serologically RB cord-288072-42sx52tn 170 9 that that WDT cord-288072-42sx52tn 170 10 were be VBD cord-288072-42sx52tn 170 11 expressed express VBN cord-288072-42sx52tn 170 12 as as IN cord-288072-42sx52tn 170 13 clinical clinical JJ cord-288072-42sx52tn 170 14 illness illness NN cord-288072-42sx52tn 170 15 is be VBZ cord-288072-42sx52tn 170 16 difficult difficult JJ cord-288072-42sx52tn 170 17 to to TO cord-288072-42sx52tn 170 18 assess assess VB cord-288072-42sx52tn 170 19 . . . cord-288072-42sx52tn 171 1 Kaye Kaye NNP cord-288072-42sx52tn 171 2 et et NNP cord-288072-42sx52tn 171 3 al al NNP cord-288072-42sx52tn 171 4 . . NNP cord-288072-42sx52tn 171 5 found find VBD cord-288072-42sx52tn 171 6 that that IN cord-288072-42sx52tn 171 7 47.3 47.3 CD cord-288072-42sx52tn 171 8 % % NN cord-288072-42sx52tn 171 9 of of IN cord-288072-42sx52tn 171 10 infections infection NNS cord-288072-42sx52tn 171 11 detected detect VBN cord-288072-42sx52tn 171 12 in in IN cord-288072-42sx52tn 171 13 children child NNS cord-288072-42sx52tn 171 14 by by IN cord-288072-42sx52tn 171 15 HAl HAl NNS cord-288072-42sx52tn 171 16 were be VBD cord-288072-42sx52tn 171 17 accompanied accompany VBN cord-288072-42sx52tn 171 18 by by IN cord-288072-42sx52tn 171 19 illness illness NN cord-288072-42sx52tn 171 20 [ [ -LRB- cord-288072-42sx52tn 171 21 4 4 CD cord-288072-42sx52tn 171 22 ] ] -RRB- cord-288072-42sx52tn 171 23 . . . cord-288072-42sx52tn 172 1 If if IN cord-288072-42sx52tn 172 2 such such PDT cord-288072-42sx52tn 172 3 a a DT cord-288072-42sx52tn 172 4 ratio ratio NN cord-288072-42sx52tn 172 5 prevailed prevail VBD cord-288072-42sx52tn 172 6 in in IN cord-288072-42sx52tn 172 7 Tecumseh Tecumseh NNP cord-288072-42sx52tn 172 8 in in IN cord-288072-42sx52tn 172 9 the the DT cord-288072-42sx52tn 172 10 1969 1969 CD cord-288072-42sx52tn 172 11 outbreak outbreak NN cord-288072-42sx52tn 172 12 , , , cord-288072-42sx52tn 172 13 it -PRON- PRP cord-288072-42sx52tn 172 14 would would MD cord-288072-42sx52tn 172 15 mean mean VB cord-288072-42sx52tn 172 16 that that IN cord-288072-42sx52tn 172 17 12.1 12.1 CD cord-288072-42sx52tn 172 18 % % NN cord-288072-42sx52tn 172 19 of of IN cord-288072-42sx52tn 172 20 all all DT cord-288072-42sx52tn 172 21 individuals individual NNS cord-288072-42sx52tn 172 22 experienced experience VBD cord-288072-42sx52tn 172 23 a a DT cord-288072-42sx52tn 172 24 symptomatic symptomatic JJ cord-288072-42sx52tn 172 25 infection infection NN cord-288072-42sx52tn 172 26 during during IN cord-288072-42sx52tn 172 27 the the DT cord-288072-42sx52tn 172 28 course course NN cord-288072-42sx52tn 172 29 of of IN cord-288072-42sx52tn 172 30 a a DT cord-288072-42sx52tn 172 31 single single JJ cord-288072-42sx52tn 172 32 season season NN cord-288072-42sx52tn 172 33 . . . cord-288072-42sx52tn 173 1 Clearly clearly RB cord-288072-42sx52tn 173 2 the the DT cord-288072-42sx52tn 173 3 coronaviruses coronaviruse NNS cord-288072-42sx52tn 173 4 make make VBP cord-288072-42sx52tn 173 5 a a DT cord-288072-42sx52tn 173 6 major major JJ cord-288072-42sx52tn 173 7 contribution contribution NN cord-288072-42sx52tn 173 8 to to IN cord-288072-42sx52tn 173 9 the the DT cord-288072-42sx52tn 173 10 overall overall JJ cord-288072-42sx52tn 173 11 burden burden NN cord-288072-42sx52tn 173 12 of of IN cord-288072-42sx52tn 173 13 respiratory respiratory JJ cord-288072-42sx52tn 173 14 illnesses illness NNS cord-288072-42sx52tn 173 15 . . . cord-288072-42sx52tn 174 1 Although although IN cord-288072-42sx52tn 174 2 illnesses illness NNS cord-288072-42sx52tn 174 3 caused cause VBN cord-288072-42sx52tn 174 4 appear appear VBP cord-288072-42sx52tn 174 5 to to TO cord-288072-42sx52tn 174 6 be be VB cord-288072-42sx52tn 174 7 mild mild JJ cord-288072-42sx52tn 174 8 , , , cord-288072-42sx52tn 174 9 their -PRON- PRP$ cord-288072-42sx52tn 174 10 frequency frequency NN cord-288072-42sx52tn 174 11 and and CC cord-288072-42sx52tn 174 12 possible possible JJ cord-288072-42sx52tn 174 13 relation relation NN cord-288072-42sx52tn 174 14 to to IN cord-288072-42sx52tn 174 15 chronic chronic JJ cord-288072-42sx52tn 174 16 respiratory respiratory JJ cord-288072-42sx52tn 174 17 disease disease NN cord-288072-42sx52tn 174 18 makes make VBZ cord-288072-42sx52tn 174 19 further further JJ cord-288072-42sx52tn 174 20 understanding understanding NN cord-288072-42sx52tn 174 21 of of IN cord-288072-42sx52tn 174 22 their -PRON- PRP$ cord-288072-42sx52tn 174 23 behavior behavior NN cord-288072-42sx52tn 174 24 essential essential JJ cord-288072-42sx52tn 174 25 . . . cord-288072-42sx52tn 175 1 Isolation isolation NN cord-288072-42sx52tn 175 2 from from IN cord-288072-42sx52tn 175 3 man man NN cord-288072-42sx52tn 175 4 of of IN cord-288072-42sx52tn 175 5 " " `` cord-288072-42sx52tn 175 6 avian avian JJ cord-288072-42sx52tn 175 7 infectious infectious JJ cord-288072-42sx52tn 175 8 bronchitis bronchitis NN cord-288072-42sx52tn 175 9 virus virus NN cord-288072-42sx52tn 175 10 - - : cord-288072-42sx52tn 175 11 like like JJ cord-288072-42sx52tn 175 12 " " `` cord-288072-42sx52tn 175 13 viruses virus NNS cord-288072-42sx52tn 175 14 ( ( -LRB- cord-288072-42sx52tn 175 15 coronaviruses coronaviruse NNS cord-288072-42sx52tn 175 16 ) ) -RRB- cord-288072-42sx52tn 175 17 similar similar JJ cord-288072-42sx52tn 175 18 to to IN cord-288072-42sx52tn 175 19 229E 229e CD cord-288072-42sx52tn 175 20 virus virus NN cord-288072-42sx52tn 175 21 , , , cord-288072-42sx52tn 175 22 with with IN cord-288072-42sx52tn 175 23 some some DT cord-288072-42sx52tn 175 24 epidemiological epidemiological JJ cord-288072-42sx52tn 175 25 observations observation NNS cord-288072-42sx52tn 175 26 Coronavirus Coronavirus NNP cord-288072-42sx52tn 175 27 infections infection NNS cord-288072-42sx52tn 175 28 in in IN cord-288072-42sx52tn 175 29 working work VBG cord-288072-42sx52tn 175 30 adults adult NNS cord-288072-42sx52tn 175 31 : : : cord-288072-42sx52tn 175 32 eight eight CD cord-288072-42sx52tn 175 33 - - HYPH cord-288072-42sx52tn 175 34 year year NN cord-288072-42sx52tn 175 35 study study NN cord-288072-42sx52tn 175 36 with with IN cord-288072-42sx52tn 175 37 229E 229e CD cord-288072-42sx52tn 175 38 and and CC cord-288072-42sx52tn 175 39 OC OC NNP cord-288072-42sx52tn 175 40 43 43 CD cord-288072-42sx52tn 175 41 Seroepidemiologic Seroepidemiologic NNP cord-288072-42sx52tn 175 42 studies study NNS cord-288072-42sx52tn 175 43 of of IN cord-288072-42sx52tn 175 44 coronavirus coronavirus NN cord-288072-42sx52tn 175 45 infection infection NN cord-288072-42sx52tn 175 46 in in IN cord-288072-42sx52tn 175 47 adults adult NNS cord-288072-42sx52tn 175 48 and and CC cord-288072-42sx52tn 175 49 children child NNS cord-288072-42sx52tn 176 1 Seroepidemiologic Seroepidemiologic NNP cord-288072-42sx52tn 176 2 survey survey NN cord-288072-42sx52tn 176 3 of of IN cord-288072-42sx52tn 176 4 coronavirus coronavirus NN cord-288072-42sx52tn 176 5 ( ( -LRB- cord-288072-42sx52tn 176 6 strain strain NN cord-288072-42sx52tn 176 7 OC OC NNP cord-288072-42sx52tn 176 8 43 43 CD cord-288072-42sx52tn 176 9 ) ) -RRB- cord-288072-42sx52tn 176 10 related relate VBN cord-288072-42sx52tn 176 11 infections infection NNS cord-288072-42sx52tn 176 12 in in IN cord-288072-42sx52tn 176 13 a a DT cord-288072-42sx52tn 176 14 children child NNS cord-288072-42sx52tn 176 15 's 's POS cord-288072-42sx52tn 176 16 population population NN cord-288072-42sx52tn 176 17 A a DT cord-288072-42sx52tn 176 18 new new JJ cord-288072-42sx52tn 176 19 virus virus NN cord-288072-42sx52tn 176 20 isolated isolate VBN cord-288072-42sx52tn 176 21 from from IN cord-288072-42sx52tn 176 22 the the DT cord-288072-42sx52tn 176 23 human human JJ cord-288072-42sx52tn 176 24 respiratory respiratory JJ cord-288072-42sx52tn 176 25 tract tract NN cord-288072-42sx52tn 176 26 Growth growth NN cord-288072-42sx52tn 176 27 in in IN cord-288072-42sx52tn 176 28 suckling suckle VBG cord-288072-42sx52tn 176 29 - - HYPH cord-288072-42sx52tn 176 30 mouse mouse NN cord-288072-42sx52tn 176 31 brain brain NN cord-288072-42sx52tn 176 32 of of IN cord-288072-42sx52tn 176 33 " " `` cord-288072-42sx52tn 176 34 IBV IBV NNP cord-288072-42sx52tn 176 35 - - HYPH cord-288072-42sx52tn 176 36 like like JJ cord-288072-42sx52tn 176 37 " " '' cord-288072-42sx52tn 176 38 viruses virus NNS cord-288072-42sx52tn 176 39 from from IN cord-288072-42sx52tn 176 40 patients patient NNS cord-288072-42sx52tn 176 41 with with IN cord-288072-42sx52tn 176 42 upper upper JJ cord-288072-42sx52tn 176 43 respiratory respiratory JJ cord-288072-42sx52tn 176 44 tract tract NN cord-288072-42sx52tn 176 45 disease disease NN cord-288072-42sx52tn 177 1 The the DT cord-288072-42sx52tn 177 2 adaptation adaptation NN cord-288072-42sx52tn 177 3 of of IN cord-288072-42sx52tn 177 4 two two CD cord-288072-42sx52tn 177 5 human human JJ cord-288072-42sx52tn 177 6 corona corona NN cord-288072-42sx52tn 177 7 - - HYPH cord-288072-42sx52tn 177 8 Monto Monto NNP cord-288072-42sx52tn 177 9 and and CC cord-288072-42sx52tn 177 10 Lim Lim NNP cord-288072-42sx52tn 177 11 virus virus NN cord-288072-42sx52tn 177 12 strains strain NNS cord-288072-42sx52tn 177 13 ( ( -LRB- cord-288072-42sx52tn 177 14 OC38 OC38 NNP cord-288072-42sx52tn 177 15 and and CC cord-288072-42sx52tn 177 16 OC43 OC43 NNP cord-288072-42sx52tn 177 17 ) ) -RRB- cord-288072-42sx52tn 177 18 to to IN cord-288072-42sx52tn 177 19 growth growth NN cord-288072-42sx52tn 177 20 in in IN cord-288072-42sx52tn 177 21 cell cell NN cord-288072-42sx52tn 177 22 monolayers monolayer NNS cord-288072-42sx52tn 178 1 Some some DT cord-288072-42sx52tn 178 2 characteristics characteristic NNS cord-288072-42sx52tn 178 3 of of IN cord-288072-42sx52tn 178 4 hemagglutination hemagglutination NN cord-288072-42sx52tn 178 5 of of IN cord-288072-42sx52tn 178 6 certain certain JJ cord-288072-42sx52tn 178 7 strains strain NNS cord-288072-42sx52tn 178 8 of of IN cord-288072-42sx52tn 178 9 " " `` cord-288072-42sx52tn 178 10 IBVlike IBVlike NNP cord-288072-42sx52tn 178 11 " " '' cord-288072-42sx52tn 178 12 virus virus NN cord-288072-42sx52tn 178 13 Hemadsorption hemadsorption NN cord-288072-42sx52tn 178 14 by by IN cord-288072-42sx52tn 178 15 coronavirus coronavirus NN cord-288072-42sx52tn 178 16 strain strain VBP cord-288072-42sx52tn 178 17 OC43 OC43 NNP cord-288072-42sx52tn 178 18 The the DT cord-288072-42sx52tn 178 19 Tecumseh Tecumseh NNP cord-288072-42sx52tn 178 20 study study NN cord-288072-42sx52tn 178 21 of of IN cord-288072-42sx52tn 178 22 respiratory respiratory JJ cord-288072-42sx52tn 178 23 illness illness NN cord-288072-42sx52tn 178 24 . . . cord-288072-42sx52tn 179 1 III III NNP cord-288072-42sx52tn 179 2 . . . cord-288072-42sx52tn 180 1 Incidence incidence NN cord-288072-42sx52tn 180 2 and and CC cord-288072-42sx52tn 180 3 periodicity periodicity NN cord-288072-42sx52tn 180 4 of of IN cord-288072-42sx52tn 180 5 respiratory respiratory JJ cord-288072-42sx52tn 180 6 syncytial syncytial JJ cord-288072-42sx52tn 180 7 virus virus NN cord-288072-42sx52tn 180 8 and and CC cord-288072-42sx52tn 180 9 Mycoplasma Mycoplasma NNP cord-288072-42sx52tn 180 10 pneumoniae pneumoniae NN cord-288072-42sx52tn 180 11 infections infection NNS cord-288072-42sx52tn 180 12 Community community NN cord-288072-42sx52tn 180 13 - - HYPH cord-288072-42sx52tn 180 14 wide wide JJ cord-288072-42sx52tn 180 15 outbreak outbreak NN cord-288072-42sx52tn 180 16 of of IN cord-288072-42sx52tn 180 17 infection infection NN cord-288072-42sx52tn 180 18 with with IN cord-288072-42sx52tn 180 19 a a DT cord-288072-42sx52tn 180 20 229E 229e CD cord-288072-42sx52tn 180 21 - - HYPH cord-288072-42sx52tn 180 22 like like JJ cord-288072-42sx52tn 180 23 coronavirus coronavirus NN cord-288072-42sx52tn 180 24 in in IN cord-288072-42sx52tn 180 25 Tecumseh Tecumseh NNP cord-288072-42sx52tn 180 26 , , , cord-288072-42sx52tn 180 27 Michigan Michigan NNP cord-288072-42sx52tn 181 1 The the DT cord-288072-42sx52tn 181 2 Tecumseh Tecumseh NNP cord-288072-42sx52tn 181 3 study study NN cord-288072-42sx52tn 181 4 of of IN cord-288072-42sx52tn 181 5 respiratory respiratory JJ cord-288072-42sx52tn 181 6 illness illness NN cord-288072-42sx52tn 181 7 . . . cord-288072-42sx52tn 182 1 I. I. NNP cord-288072-42sx52tn 182 2 Plan Plan NNP cord-288072-42sx52tn 182 3 of of IN cord-288072-42sx52tn 182 4 study study NN cord-288072-42sx52tn 182 5 and and CC cord-288072-42sx52tn 182 6 observations observation NNS cord-288072-42sx52tn 182 7 on on IN cord-288072-42sx52tn 182 8 syndromes syndrome NNS cord-288072-42sx52tn 182 9 of of IN cord-288072-42sx52tn 182 10 acute acute JJ cord-288072-42sx52tn 182 11 respiratory respiratory JJ cord-288072-42sx52tn 182 12 disease disease NN cord-288072-42sx52tn 183 1 The the DT cord-288072-42sx52tn 183 2 Tecumseh Tecumseh NNP cord-288072-42sx52tn 183 3 study study NN cord-288072-42sx52tn 183 4 of of IN cord-288072-42sx52tn 183 5 respiratory respiratory JJ cord-288072-42sx52tn 183 6 illness illness NN cord-288072-42sx52tn 183 7 . . . cord-288072-42sx52tn 184 1 II II NNP cord-288072-42sx52tn 184 2 . . . cord-288072-42sx52tn 185 1 Patterns pattern NNS cord-288072-42sx52tn 185 2 of of IN cord-288072-42sx52tn 185 3 occurrence occurrence NN cord-288072-42sx52tn 185 4 of of IN cord-288072-42sx52tn 185 5 infection infection NN cord-288072-42sx52tn 185 6 with with IN cord-288072-42sx52tn 185 7 respiratory respiratory JJ cord-288072-42sx52tn 185 8 pathogens pathogen NNS cord-288072-42sx52tn 185 9 , , , cord-288072-42sx52tn 185 10 1965 1965 CD cord-288072-42sx52tn 185 11 - - SYM cord-288072-42sx52tn 185 12 1969 1969 CD cord-288072-42sx52tn 185 13 Recovery Recovery NNP cord-288072-42sx52tn 185 14 in in IN cord-288072-42sx52tn 185 15 tracheal tracheal JJ cord-288072-42sx52tn 185 16 organ organ NN cord-288072-42sx52tn 185 17 cultures culture NNS cord-288072-42sx52tn 185 18 of of IN cord-288072-42sx52tn 185 19 novel novel NN cord-288072-42sx52tn 185 20 viruses virus NNS cord-288072-42sx52tn 185 21 from from IN cord-288072-42sx52tn 185 22 patients patient NNS cord-288072-42sx52tn 185 23 with with IN cord-288072-42sx52tn 185 24 respiratory respiratory JJ cord-288072-42sx52tn 185 25 disease disease NN cord-288072-42sx52tn 185 26 Cultivation cultivation NN cord-288072-42sx52tn 185 27 of of IN cord-288072-42sx52tn 185 28 a a DT cord-288072-42sx52tn 185 29 novel novel JJ cord-288072-42sx52tn 185 30 type type NN cord-288072-42sx52tn 185 31 of of IN cord-288072-42sx52tn 185 32 common common JJ cord-288072-42sx52tn 185 33 - - HYPH cord-288072-42sx52tn 185 34 cold cold JJ cord-288072-42sx52tn 185 35 virus virus NN cord-288072-42sx52tn 185 36 in in IN cord-288072-42sx52tn 185 37 organ organ NN cord-288072-42sx52tn 185 38 cultures culture NNS cord-288072-42sx52tn 185 39 Coronavirus Coronavirus NNP cord-288072-42sx52tn 185 40 antibody antibody NN cord-288072-42sx52tn 185 41 titers titer NNS cord-288072-42sx52tn 185 42 in in IN cord-288072-42sx52tn 185 43 sera sera NNP cord-288072-42sx52tn 185 44 of of IN cord-288072-42sx52tn 185 45 healthy healthy JJ cord-288072-42sx52tn 185 46 adults adult NNS cord-288072-42sx52tn 185 47 and and CC cord-288072-42sx52tn 185 48 experimentally experimentally RB cord-288072-42sx52tn 185 49 infected infect VBN cord-288072-42sx52tn 185 50 volunteers volunteer NNS cord-288072-42sx52tn 185 51 Antigenic antigenic JJ cord-288072-42sx52tn 185 52 relationships relationship NNS cord-288072-42sx52tn 185 53 among among IN cord-288072-42sx52tn 185 54 the the DT cord-288072-42sx52tn 185 55 coronaviruses coronaviruse NNS cord-288072-42sx52tn 185 56 of of IN cord-288072-42sx52tn 185 57 man man NN cord-288072-42sx52tn 185 58 and and CC cord-288072-42sx52tn 185 59 between between IN cord-288072-42sx52tn 185 60 human human JJ cord-288072-42sx52tn 185 61 and and CC cord-288072-42sx52tn 185 62 animal animal NN cord-288072-42sx52tn 185 63 coronaviruses coronaviruse NNS cord-288072-42sx52tn 185 64 Antigenic antigenic JJ cord-288072-42sx52tn 185 65 relationships relationship NNS cord-288072-42sx52tn 185 66 amongst amongst IN cord-288072-42sx52tn 185 67 coronaviruses coronaviruse NNS cord-288072-42sx52tn 186 1 Virologic Virologic NNP cord-288072-42sx52tn 186 2 studies study NNS cord-288072-42sx52tn 186 3 of of IN cord-288072-42sx52tn 186 4 acute acute JJ cord-288072-42sx52tn 186 5 respiratory respiratory JJ cord-288072-42sx52tn 186 6 disease disease NN cord-288072-42sx52tn 186 7 in in IN cord-288072-42sx52tn 186 8 young young JJ cord-288072-42sx52tn 186 9 adults adult NNS cord-288072-42sx52tn 186 10 . . . cord-288072-42sx52tn 187 1 V. V. NNP cord-288072-42sx52tn 187 2 Coronavirus Coronavirus NNP cord-288072-42sx52tn 187 3 229E 229e CD cord-288072-42sx52tn 187 4 infections infection NNS cord-288072-42sx52tn 187 5 during during IN cord-288072-42sx52tn 187 6 six six CD cord-288072-42sx52tn 187 7 years year NNS cord-288072-42sx52tn 187 8 of of IN cord-288072-42sx52tn 187 9 surveillance surveillance NN cord-288072-42sx52tn 188 1 The the DT cord-288072-42sx52tn 188 2 Tecumseh Tecumseh NNP cord-288072-42sx52tn 188 3 study study NN cord-288072-42sx52tn 188 4 of of IN cord-288072-42sx52tn 188 5 respiratory respiratory JJ cord-288072-42sx52tn 188 6 illness illness NN cord-288072-42sx52tn 188 7 . . . cord-288072-42sx52tn 189 1 IV IV NNP cord-288072-42sx52tn 189 2 . . . cord-288072-42sx52tn 190 1 Prevalence prevalence NN cord-288072-42sx52tn 190 2 of of IN cord-288072-42sx52tn 190 3 rhinovirus rhinovirus NN cord-288072-42sx52tn 190 4 serotypes serotype NNS cord-288072-42sx52tn 190 5 , , , cord-288072-42sx52tn 190 6 1966 1966 CD cord-288072-42sx52tn 190 7 - - SYM cord-288072-42sx52tn 190 8 1969 1969 CD cord-288072-42sx52tn 190 9 Coronavirus Coronavirus NNP cord-288072-42sx52tn 190 10 infections infection NNS cord-288072-42sx52tn 190 11 in in IN cord-288072-42sx52tn 190 12 exacerbations exacerbation NNS cord-288072-42sx52tn 190 13 of of IN cord-288072-42sx52tn 190 14 chronic chronic JJ cord-288072-42sx52tn 190 15 bronchitis bronchitis NN