id sid tid token lemma pos cord-007264-r1w9a6gc 1 1 key key NN cord-007264-r1w9a6gc 1 2 : : : cord-007264-r1w9a6gc 2 1 cord-007264-r1w9a6gc cord-007264-r1w9a6gc NN cord-007264-r1w9a6gc 2 2 authors author NNS cord-007264-r1w9a6gc 2 3 : : : cord-007264-r1w9a6gc 2 4 Turner Turner NNP cord-007264-r1w9a6gc 2 5 , , , cord-007264-r1w9a6gc 2 6 Ronald Ronald NNP cord-007264-r1w9a6gc 2 7 B. B. NNP cord-007264-r1w9a6gc 2 8 title title NN cord-007264-r1w9a6gc 2 9 : : : cord-007264-r1w9a6gc 2 10 Rhinovirus Rhinovirus NNP cord-007264-r1w9a6gc 2 11 Infection infection NN cord-007264-r1w9a6gc 2 12 of of IN cord-007264-r1w9a6gc 2 13 Human Human NNP cord-007264-r1w9a6gc 2 14 Embryonic Embryonic NNP cord-007264-r1w9a6gc 2 15 Lung Lung NNP cord-007264-r1w9a6gc 2 16 Fibroblasts Fibroblasts NNPS cord-007264-r1w9a6gc 2 17 Induces induce VBZ cord-007264-r1w9a6gc 2 18 the the DT cord-007264-r1w9a6gc 2 19 Production production NN cord-007264-r1w9a6gc 2 20 of of IN cord-007264-r1w9a6gc 2 21 a a DT cord-007264-r1w9a6gc 2 22 Chemoattractant Chemoattractant NNP cord-007264-r1w9a6gc 2 23 for for IN cord-007264-r1w9a6gc 2 24 Polymorphonuclear Polymorphonuclear NNP cord-007264-r1w9a6gc 2 25 Leukocytes Leukocytes NNP cord-007264-r1w9a6gc 2 26 date date NN cord-007264-r1w9a6gc 2 27 : : : cord-007264-r1w9a6gc 2 28 1988 1988 CD cord-007264-r1w9a6gc 2 29 - - SYM cord-007264-r1w9a6gc 2 30 02 02 CD cord-007264-r1w9a6gc 2 31 - - SYM cord-007264-r1w9a6gc 2 32 17 17 CD cord-007264-r1w9a6gc 2 33 journal journal NN cord-007264-r1w9a6gc 2 34 : : : cord-007264-r1w9a6gc 3 1 J J NNP cord-007264-r1w9a6gc 3 2 Infect infect VBP cord-007264-r1w9a6gc 3 3 Dis Dis NNP cord-007264-r1w9a6gc 3 4 DOI doi NN cord-007264-r1w9a6gc 3 5 : : : cord-007264-r1w9a6gc 4 1 10.1093 10.1093 CD cord-007264-r1w9a6gc 4 2 / / SYM cord-007264-r1w9a6gc 4 3 infdis/157.2.346 infdis/157.2.346 NN cord-007264-r1w9a6gc 4 4 sha sha NNP cord-007264-r1w9a6gc 5 1 : : : cord-007264-r1w9a6gc 5 2 f7007f31e73bf83bdcf2516d0f992ea35d01607f f7007f31e73bf83bdcf2516d0f992ea35d01607f NNP cord-007264-r1w9a6gc 5 3 doc_id doc_id CD cord-007264-r1w9a6gc 6 1 : : : cord-007264-r1w9a6gc 6 2 7264 7264 CD cord-007264-r1w9a6gc 6 3 cord_uid cord_uid NNS cord-007264-r1w9a6gc 6 4 : : : cord-007264-r1w9a6gc 6 5 r1w9a6gc r1w9a6gc NNP cord-007264-r1w9a6gc 6 6 Polymorphonuclear Polymorphonuclear NNP cord-007264-r1w9a6gc 6 7 leukocytes leukocyte NNS cord-007264-r1w9a6gc 6 8 ( ( -LRB- cord-007264-r1w9a6gc 6 9 PMNLs pmnl NNS cord-007264-r1w9a6gc 6 10 ) ) -RRB- cord-007264-r1w9a6gc 6 11 appear appear VBP cord-007264-r1w9a6gc 6 12 in in IN cord-007264-r1w9a6gc 6 13 the the DT cord-007264-r1w9a6gc 6 14 nasal nasal NN cord-007264-r1w9a6gc 6 15 mucosa mucosa JJ cord-007264-r1w9a6gc 6 16 during during IN cord-007264-r1w9a6gc 6 17 rhinovirus rhinovirus JJ cord-007264-r1w9a6gc 6 18 colds cold NNS cord-007264-r1w9a6gc 6 19 before before IN cord-007264-r1w9a6gc 6 20 the the DT cord-007264-r1w9a6gc 6 21 onset onset NN cord-007264-r1w9a6gc 6 22 of of IN cord-007264-r1w9a6gc 6 23 symptoms symptom NNS cord-007264-r1w9a6gc 6 24 . . . cord-007264-r1w9a6gc 7 1 This this DT cord-007264-r1w9a6gc 7 2 study study NN cord-007264-r1w9a6gc 7 3 describes describe VBZ cord-007264-r1w9a6gc 7 4 a a DT cord-007264-r1w9a6gc 7 5 chemoattractant chemoattractant NN cord-007264-r1w9a6gc 7 6 for for IN cord-007264-r1w9a6gc 7 7 PMNLs pmnl NNS cord-007264-r1w9a6gc 7 8 that that WDT cord-007264-r1w9a6gc 7 9 is be VBZ cord-007264-r1w9a6gc 7 10 elaborated elaborate VBN cord-007264-r1w9a6gc 7 11 by by IN cord-007264-r1w9a6gc 7 12 human human JJ cord-007264-r1w9a6gc 7 13 embryonic embryonic JJ cord-007264-r1w9a6gc 7 14 lung lung NN cord-007264-r1w9a6gc 7 15 fibroblast fibroblast NN cord-007264-r1w9a6gc 7 16 cells cell NNS cord-007264-r1w9a6gc 7 17 infected infect VBN cord-007264-r1w9a6gc 7 18 with with IN cord-007264-r1w9a6gc 7 19 rhinovirus rhinovirus NN cord-007264-r1w9a6gc 7 20 . . . cord-007264-r1w9a6gc 8 1 Chemotaxis chemotaxis NN cord-007264-r1w9a6gc 8 2 assays assay NNS cord-007264-r1w9a6gc 8 3 were be VBD cord-007264-r1w9a6gc 8 4 done do VBN cord-007264-r1w9a6gc 8 5 in in IN cord-007264-r1w9a6gc 8 6 a a DT cord-007264-r1w9a6gc 8 7 48-well 48-well CD cord-007264-r1w9a6gc 8 8 microchemotaxis microchemotaxis JJ cord-007264-r1w9a6gc 8 9 chamber chamber NN cord-007264-r1w9a6gc 8 10 with with IN cord-007264-r1w9a6gc 8 11 normal normal JJ cord-007264-r1w9a6gc 8 12 adult adult NN cord-007264-r1w9a6gc 8 13 PMNLs pmnl NNS cord-007264-r1w9a6gc 8 14 . . . cord-007264-r1w9a6gc 9 1 Medium medium NN cord-007264-r1w9a6gc 9 2 supernatants supernatant NNS cord-007264-r1w9a6gc 9 3 from from IN cord-007264-r1w9a6gc 9 4 rhinovirus rhinovirus NN cord-007264-r1w9a6gc 9 5 - - HYPH cord-007264-r1w9a6gc 9 6 infected infect VBN cord-007264-r1w9a6gc 9 7 cellculture cellculture NN cord-007264-r1w9a6gc 9 8 attracted attract VBD cord-007264-r1w9a6gc 9 9 87 87 CD cord-007264-r1w9a6gc 9 10 ± ± CD cord-007264-r1w9a6gc 9 11 6 6 CD cord-007264-r1w9a6gc 10 1 ( ( -LRB- cord-007264-r1w9a6gc 10 2 mean mean VB cord-007264-r1w9a6gc 10 3 ± ± NNP cord-007264-r1w9a6gc 10 4 SE SE NNP cord-007264-r1w9a6gc 10 5 ) ) -RRB- cord-007264-r1w9a6gc 11 1 PMNLs/10 PMNLs/10 NNP cord-007264-r1w9a6gc 11 2 high high JJ cord-007264-r1w9a6gc 11 3 - - HYPH cord-007264-r1w9a6gc 11 4 power power NN cord-007264-r1w9a6gc 11 5 fields field NNS cord-007264-r1w9a6gc 11 6 ( ( -LRB- cord-007264-r1w9a6gc 11 7 ×450 ×450 NFP cord-007264-r1w9a6gc 11 8 ) ) -RRB- cord-007264-r1w9a6gc 11 9 compared compare VBN cord-007264-r1w9a6gc 11 10 with with IN cord-007264-r1w9a6gc 11 11 38 38 CD cord-007264-r1w9a6gc 11 12 ± ± CD cord-007264-r1w9a6gc 11 13 6 6 CD cord-007264-r1w9a6gc 11 14 PMNLs/10 PMNLs/10 NNP cord-007264-r1w9a6gc 11 15 highpower highpower NN cord-007264-r1w9a6gc 11 16 fields field NNS cord-007264-r1w9a6gc 11 17 attracted attract VBN cord-007264-r1w9a6gc 11 18 by by IN cord-007264-r1w9a6gc 11 19 medium medium NN cord-007264-r1w9a6gc 11 20 from from IN cord-007264-r1w9a6gc 11 21 uninfected uninfected JJ cord-007264-r1w9a6gc 11 22 cell cell NN cord-007264-r1w9a6gc 11 23 cultures culture NNS cord-007264-r1w9a6gc 11 24 ( ( -LRB- cord-007264-r1w9a6gc 11 25 P p NN cord-007264-r1w9a6gc 11 26 < < XX cord-007264-r1w9a6gc 11 27 .0001 .0001 XX cord-007264-r1w9a6gc 11 28 ) ) -RRB- cord-007264-r1w9a6gc 11 29 . . . cord-007264-r1w9a6gc 12 1 Elaboration elaboration NN cord-007264-r1w9a6gc 12 2 of of IN cord-007264-r1w9a6gc 12 3 the the DT cord-007264-r1w9a6gc 12 4 chemoattractant chemoattractant NN cord-007264-r1w9a6gc 12 5 was be VBD cord-007264-r1w9a6gc 12 6 not not RB cord-007264-r1w9a6gc 12 7 a a DT cord-007264-r1w9a6gc 12 8 result result NN cord-007264-r1w9a6gc 12 9 of of IN cord-007264-r1w9a6gc 12 10 cell cell NN cord-007264-r1w9a6gc 12 11 destruction destruction NN cord-007264-r1w9a6gc 12 12 and and CC cord-007264-r1w9a6gc 12 13 did do VBD cord-007264-r1w9a6gc 12 14 not not RB cord-007264-r1w9a6gc 12 15 require require VB cord-007264-r1w9a6gc 12 16 the the DT cord-007264-r1w9a6gc 12 17 presence presence NN cord-007264-r1w9a6gc 12 18 of of IN cord-007264-r1w9a6gc 12 19 infectious infectious JJ cord-007264-r1w9a6gc 12 20 virus virus NN cord-007264-r1w9a6gc 12 21 . . . cord-007264-r1w9a6gc 13 1 This this DT cord-007264-r1w9a6gc 13 2 chemoattractant chemoattractant NN cord-007264-r1w9a6gc 13 3 produced produce VBN cord-007264-r1w9a6gc 13 4 by by IN cord-007264-r1w9a6gc 13 5 human human JJ cord-007264-r1w9a6gc 13 6 fibroblast fibroblast NN cord-007264-r1w9a6gc 13 7 cells cell NNS cord-007264-r1w9a6gc 13 8 may may MD cord-007264-r1w9a6gc 13 9 contribute contribute VB cord-007264-r1w9a6gc 13 10 to to IN cord-007264-r1w9a6gc 13 11 the the DT cord-007264-r1w9a6gc 13 12 influx influx NN cord-007264-r1w9a6gc 13 13 of of IN cord-007264-r1w9a6gc 13 14 PMNLs pmnl NNS cord-007264-r1w9a6gc 13 15 into into IN cord-007264-r1w9a6gc 13 16 the the DT cord-007264-r1w9a6gc 13 17 nasal nasal NN cord-007264-r1w9a6gc 13 18 mucosa mucosa JJ cord-007264-r1w9a6gc 13 19 during during IN cord-007264-r1w9a6gc 13 20 rhinovirus rhinovirus NN cord-007264-r1w9a6gc 13 21 infection infection NN cord-007264-r1w9a6gc 13 22 . . . cord-007264-r1w9a6gc 14 1 The the DT cord-007264-r1w9a6gc 14 2 PMNLs pmnl NNS cord-007264-r1w9a6gc 14 3 may may MD cord-007264-r1w9a6gc 14 4 , , , cord-007264-r1w9a6gc 14 5 in in IN cord-007264-r1w9a6gc 14 6 turn turn NN cord-007264-r1w9a6gc 14 7 , , , cord-007264-r1w9a6gc 14 8 have have VB cord-007264-r1w9a6gc 14 9 a a DT cord-007264-r1w9a6gc 14 10 role role NN cord-007264-r1w9a6gc 14 11 in in IN cord-007264-r1w9a6gc 14 12 producing produce VBG cord-007264-r1w9a6gc 14 13 symptoms symptom NNS cord-007264-r1w9a6gc 14 14 of of IN cord-007264-r1w9a6gc 14 15 the the DT cord-007264-r1w9a6gc 14 16 common common JJ cord-007264-r1w9a6gc 14 17 cold cold NN cord-007264-r1w9a6gc 14 18 . . . cord-007264-r1w9a6gc 15 1 Rhinoviruses Rhinoviruses NNP cord-007264-r1w9a6gc 15 2 are be VBP cord-007264-r1w9a6gc 15 3 the the DT cord-007264-r1w9a6gc 15 4 pathogens pathogen NNS cord-007264-r1w9a6gc 15 5 most most RBS cord-007264-r1w9a6gc 15 6 frequently frequently RB cord-007264-r1w9a6gc 15 7 associated associate VBN cord-007264-r1w9a6gc 15 8 with with IN cord-007264-r1w9a6gc 15 9 the the DT cord-007264-r1w9a6gc 15 10 common common JJ cord-007264-r1w9a6gc 15 11 cold cold NN cord-007264-r1w9a6gc 15 12 [ [ -LRB- cord-007264-r1w9a6gc 15 13 1 1 CD cord-007264-r1w9a6gc 15 14 ] ] -RRB- cord-007264-r1w9a6gc 15 15 . . . cord-007264-r1w9a6gc 16 1 The the DT cord-007264-r1w9a6gc 16 2 pathogenesis pathogenesis NN cord-007264-r1w9a6gc 16 3 of of IN cord-007264-r1w9a6gc 16 4 the the DT cord-007264-r1w9a6gc 16 5 symptoms symptom NNS cord-007264-r1w9a6gc 16 6 of of IN cord-007264-r1w9a6gc 16 7 rhinovirus rhinovirus NN cord-007264-r1w9a6gc 16 8 infection infection NN cord-007264-r1w9a6gc 16 9 is be VBZ cord-007264-r1w9a6gc 16 10 not not RB cord-007264-r1w9a6gc 16 11 known know VBN cord-007264-r1w9a6gc 16 12 , , , cord-007264-r1w9a6gc 16 13 but but CC cord-007264-r1w9a6gc 16 14 it -PRON- PRP cord-007264-r1w9a6gc 16 15 has have VBZ cord-007264-r1w9a6gc 16 16 been be VBN cord-007264-r1w9a6gc 16 17 suggested suggest VBN cord-007264-r1w9a6gc 16 18 that that IN cord-007264-r1w9a6gc 16 19 the the DT cord-007264-r1w9a6gc 16 20 host host NN cord-007264-r1w9a6gc 16 21 response response NN cord-007264-r1w9a6gc 16 22 to to IN cord-007264-r1w9a6gc 16 23 the the DT cord-007264-r1w9a6gc 16 24 virus virus NN cord-007264-r1w9a6gc 16 25 may may MD cord-007264-r1w9a6gc 16 26 cause cause VB cord-007264-r1w9a6gc 16 27 at at IN cord-007264-r1w9a6gc 16 28 least least JJS cord-007264-r1w9a6gc 16 29 some some DT cord-007264-r1w9a6gc 16 30 of of IN cord-007264-r1w9a6gc 16 31 the the DT cord-007264-r1w9a6gc 16 32 manifestations manifestation NNS cord-007264-r1w9a6gc 16 33 of of IN cord-007264-r1w9a6gc 16 34 infection infection NN cord-007264-r1w9a6gc 16 35 [ [ -LRB- cord-007264-r1w9a6gc 16 36 2 2 CD cord-007264-r1w9a6gc 16 37 , , , cord-007264-r1w9a6gc 16 38 3 3 CD cord-007264-r1w9a6gc 16 39 ] ] -RRB- cord-007264-r1w9a6gc 16 40 . . . cord-007264-r1w9a6gc 17 1 Recent recent JJ cord-007264-r1w9a6gc 17 2 studies study NNS cord-007264-r1w9a6gc 17 3 in in IN cord-007264-r1w9a6gc 17 4 human human JJ cord-007264-r1w9a6gc 17 5 volunteers volunteer NNS cord-007264-r1w9a6gc 17 6 have have VBP cord-007264-r1w9a6gc 17 7 shown show VBN cord-007264-r1w9a6gc 17 8 that that IN cord-007264-r1w9a6gc 17 9 PMNLs pmnl NNS cord-007264-r1w9a6gc 17 10 appear appear VBP cord-007264-r1w9a6gc 17 11 in in IN cord-007264-r1w9a6gc 17 12 the the DT cord-007264-r1w9a6gc 17 13 nasal nasal NN cord-007264-r1w9a6gc 17 14 mucosa mucosa JJ cord-007264-r1w9a6gc 17 15 early early RB cord-007264-r1w9a6gc 17 16 in in IN cord-007264-r1w9a6gc 17 17 the the DT cord-007264-r1w9a6gc 17 18 course course NN cord-007264-r1w9a6gc 17 19 of of IN cord-007264-r1w9a6gc 17 20 infection infection NN cord-007264-r1w9a6gc 17 21 , , , cord-007264-r1w9a6gc 17 22 before before IN cord-007264-r1w9a6gc 17 23 the the DT cord-007264-r1w9a6gc 17 24 appearance appearance NN cord-007264-r1w9a6gc 17 25 of of IN cord-007264-r1w9a6gc 17 26 symptoms symptom NNS cord-007264-r1w9a6gc 17 27 [ [ -LRB- cord-007264-r1w9a6gc 17 28 4 4 CD cord-007264-r1w9a6gc 17 29 , , , cord-007264-r1w9a6gc 17 30 5 5 CD cord-007264-r1w9a6gc 17 31 ] ] -RRB- cord-007264-r1w9a6gc 17 32 . . . cord-007264-r1w9a6gc 18 1 The the DT cord-007264-r1w9a6gc 18 2 mechanism mechanism NN cord-007264-r1w9a6gc 18 3 by by IN cord-007264-r1w9a6gc 18 4 which which WDT cord-007264-r1w9a6gc 18 5 PMNLs pmnl NNS cord-007264-r1w9a6gc 18 6 are be VBP cord-007264-r1w9a6gc 18 7 attracted attract VBN cord-007264-r1w9a6gc 18 8 to to IN cord-007264-r1w9a6gc 18 9 the the DT cord-007264-r1w9a6gc 18 10 nasal nasal NN cord-007264-r1w9a6gc 18 11 mucosa mucosa NN cord-007264-r1w9a6gc 18 12 is be VBZ cord-007264-r1w9a6gc 18 13 unknown unknown JJ cord-007264-r1w9a6gc 18 14 . . . cord-007264-r1w9a6gc 19 1 The the DT cord-007264-r1w9a6gc 19 2 production production NN cord-007264-r1w9a6gc 19 3 of of IN cord-007264-r1w9a6gc 19 4 chemoattractants chemoattractant NNS cord-007264-r1w9a6gc 19 5 for for IN cord-007264-r1w9a6gc 19 6 PMNLs pmnl NNS cord-007264-r1w9a6gc 19 7 in in IN cord-007264-r1w9a6gc 19 8 response response NN cord-007264-r1w9a6gc 19 9 to to IN cord-007264-r1w9a6gc 19 10 viral viral JJ cord-007264-r1w9a6gc 19 11 infection infection NN cord-007264-r1w9a6gc 19 12 of of IN cord-007264-r1w9a6gc 19 13 cell cell NN cord-007264-r1w9a6gc 19 14 cultures culture NNS cord-007264-r1w9a6gc 19 15 has have VBZ cord-007264-r1w9a6gc 19 16 previously previously RB cord-007264-r1w9a6gc 19 17 been be VBN cord-007264-r1w9a6gc 19 18 reported report VBN cord-007264-r1w9a6gc 19 19 [ [ -LRB- cord-007264-r1w9a6gc 19 20 6 6 CD cord-007264-r1w9a6gc 19 21 ] ] -RRB- cord-007264-r1w9a6gc 19 22 [ [ -LRB- cord-007264-r1w9a6gc 19 23 7 7 CD cord-007264-r1w9a6gc 19 24 ] ] -RRB- cord-007264-r1w9a6gc 20 1 [ [ -LRB- cord-007264-r1w9a6gc 20 2 8 8 CD cord-007264-r1w9a6gc 20 3 ] ] -RRB- cord-007264-r1w9a6gc 20 4 . . . cord-007264-r1w9a6gc 21 1 Herpes Herpes NNP cord-007264-r1w9a6gc 21 2 simplex simplex NN cord-007264-r1w9a6gc 21 3 virus virus NN cord-007264-r1w9a6gc 21 4 infection infection NN cord-007264-r1w9a6gc 21 5 has have VBZ cord-007264-r1w9a6gc 21 6 been be VBN cord-007264-r1w9a6gc 21 7 shown show VBN cord-007264-r1w9a6gc 21 8 to to TO cord-007264-r1w9a6gc 21 9 be be VB cord-007264-r1w9a6gc 21 10 associated associate VBN cord-007264-r1w9a6gc 21 11 with with IN cord-007264-r1w9a6gc 21 12 a a DT cord-007264-r1w9a6gc 21 13 chemoattractant chemoattractant NN cord-007264-r1w9a6gc 21 14 that that WDT cord-007264-r1w9a6gc 21 15 is be VBZ cord-007264-r1w9a6gc 21 16 dependent dependent JJ cord-007264-r1w9a6gc 21 17 upon upon IN cord-007264-r1w9a6gc 21 18 the the DT cord-007264-r1w9a6gc 21 19 presence presence NN cord-007264-r1w9a6gc 21 20 of of IN cord-007264-r1w9a6gc 21 21 complement complement NN cord-007264-r1w9a6gc 21 22 [ [ -LRB- cord-007264-r1w9a6gc 21 23 6 6 CD cord-007264-r1w9a6gc 21 24 , , , cord-007264-r1w9a6gc 21 25 7 7 CD cord-007264-r1w9a6gc 21 26 ] ] -RRB- cord-007264-r1w9a6gc 21 27 . . . cord-007264-r1w9a6gc 22 1 In in IN cord-007264-r1w9a6gc 22 2 1972 1972 CD cord-007264-r1w9a6gc 22 3 , , , cord-007264-r1w9a6gc 22 4 Ward Ward NNP cord-007264-r1w9a6gc 22 5 and and CC cord-007264-r1w9a6gc 22 6 co co NNS cord-007264-r1w9a6gc 22 7 - - NNS cord-007264-r1w9a6gc 22 8 workers worker NNS cord-007264-r1w9a6gc 22 9 [ [ -LRB- cord-007264-r1w9a6gc 22 10 8 8 CD cord-007264-r1w9a6gc 22 11 ] ] -RRB- cord-007264-r1w9a6gc 22 12 reported report VBD cord-007264-r1w9a6gc 22 13 that that IN cord-007264-r1w9a6gc 22 14 cells cell NNS cord-007264-r1w9a6gc 22 15 infected infect VBN cord-007264-r1w9a6gc 22 16 with with IN cord-007264-r1w9a6gc 22 17 mumps mumps NN cord-007264-r1w9a6gc 22 18 virus virus NN cord-007264-r1w9a6gc 22 19 or or CC cord-007264-r1w9a6gc 22 20 Newcastle Newcastle NNP cord-007264-r1w9a6gc 22 21 disease disease NN cord-007264-r1w9a6gc 22 22 virus virus NN cord-007264-r1w9a6gc 22 23 elaborated elaborate VBD cord-007264-r1w9a6gc 22 24 a a DT cord-007264-r1w9a6gc 22 25 chemotactic chemotactic JJ cord-007264-r1w9a6gc 22 26 factor factor NN cord-007264-r1w9a6gc 22 27 that that WDT cord-007264-r1w9a6gc 22 28 was be VBD cord-007264-r1w9a6gc 22 29 not not RB cord-007264-r1w9a6gc 22 30 complement complement JJ cord-007264-r1w9a6gc 22 31 dependent dependent JJ cord-007264-r1w9a6gc 22 32 . . . cord-007264-r1w9a6gc 23 1 The the DT cord-007264-r1w9a6gc 23 2 purpose purpose NN cord-007264-r1w9a6gc 23 3 of of IN cord-007264-r1w9a6gc 23 4 the the DT cord-007264-r1w9a6gc 23 5 present present JJ cord-007264-r1w9a6gc 23 6 study study NN cord-007264-r1w9a6gc 23 7 was be VBD cord-007264-r1w9a6gc 23 8 to to TO cord-007264-r1w9a6gc 23 9 determine determine VB cord-007264-r1w9a6gc 23 10 if if IN cord-007264-r1w9a6gc 23 11 , , , cord-007264-r1w9a6gc 23 12 and and CC cord-007264-r1w9a6gc 23 13 under under IN cord-007264-r1w9a6gc 23 14 what what WDT cord-007264-r1w9a6gc 23 15 conditions condition NNS cord-007264-r1w9a6gc 23 16 , , , cord-007264-r1w9a6gc 23 17 a a DT cord-007264-r1w9a6gc 23 18 chemoattractant chemoattractant NN cord-007264-r1w9a6gc 23 19 for for IN cord-007264-r1w9a6gc 23 20 PMNLs pmnl NNS cord-007264-r1w9a6gc 23 21 might may MD cord-007264-r1w9a6gc 23 22 be be VB cord-007264-r1w9a6gc 23 23 produced produce VBN cord-007264-r1w9a6gc 23 24 in in IN cord-007264-r1w9a6gc 23 25 rhinovirus rhinovirus NN cord-007264-r1w9a6gc 23 26 infection infection NN cord-007264-r1w9a6gc 23 27 . . . cord-007264-r1w9a6gc 24 1 Growth growth NN cord-007264-r1w9a6gc 24 2 ofrhinovirus ofrhinovirus NNP cord-007264-r1w9a6gc 24 3 in in IN cord-007264-r1w9a6gc 24 4 cellculture cellculture NN cord-007264-r1w9a6gc 24 5 . . . cord-007264-r1w9a6gc 25 1 We -PRON- PRP cord-007264-r1w9a6gc 25 2 used use VBD cord-007264-r1w9a6gc 25 3 human human JJ cord-007264-r1w9a6gc 25 4 embryonic embryonic JJ cord-007264-r1w9a6gc 25 5 lung lung NN cord-007264-r1w9a6gc 25 6 fibroblast fibroblast NN cord-007264-r1w9a6gc 25 7 cells cell NNS cord-007264-r1w9a6gc 25 8 ( ( -LRB- cord-007264-r1w9a6gc 25 9 MRC-5 MRC-5 NNP cord-007264-r1w9a6gc 25 10 ; ; : cord-007264-r1w9a6gc 25 11 Earl Earl NNP cord-007264-r1w9a6gc 25 12 - - HYPH cord-007264-r1w9a6gc 25 13 Clay Clay NNP cord-007264-r1w9a6gc 25 14 Laboratories Laboratories NNPS cord-007264-r1w9a6gc 25 15 , , , cord-007264-r1w9a6gc 25 16 Novato Novato NNP cord-007264-r1w9a6gc 25 17 , , , cord-007264-r1w9a6gc 25 18 Calif Calif NNP cord-007264-r1w9a6gc 25 19 ) ) -RRB- cord-007264-r1w9a6gc 25 20 at at IN cord-007264-r1w9a6gc 25 21 passages passage NNS cord-007264-r1w9a6gc 25 22 23 23 CD cord-007264-r1w9a6gc 25 23 - - SYM cord-007264-r1w9a6gc 25 24 25 25 CD cord-007264-r1w9a6gc 25 25 and and CC cord-007264-r1w9a6gc 25 26 human human JJ cord-007264-r1w9a6gc 25 27 foreskin foreskin NN cord-007264-r1w9a6gc 25 28 fibroblast fibroblast NN cord-007264-r1w9a6gc 25 29 cells cell NNS cord-007264-r1w9a6gc 25 30 at at IN cord-007264-r1w9a6gc 25 31 passages passage NNS cord-007264-r1w9a6gc 25 32 6 6 CD cord-007264-r1w9a6gc 25 33 - - SYM cord-007264-r1w9a6gc 25 34 10 10 CD cord-007264-r1w9a6gc 25 35 . . . cord-007264-r1w9a6gc 26 1 Cells cell NNS cord-007264-r1w9a6gc 26 2 were be VBD cord-007264-r1w9a6gc 26 3 grown grow VBN cord-007264-r1w9a6gc 26 4 in in IN cord-007264-r1w9a6gc 26 5 16 16 CD cord-007264-r1w9a6gc 26 6 x x SYM cord-007264-r1w9a6gc 26 7 125-mm 125-mm CD cord-007264-r1w9a6gc 26 8 cell cell NN cord-007264-r1w9a6gc 26 9 culture culture NN cord-007264-r1w9a6gc 26 10 tubes tube NNS cord-007264-r1w9a6gc 26 11 or or CC cord-007264-r1w9a6gc 26 12 in in IN cord-007264-r1w9a6gc 26 13 25-cm 25-cm CD cord-007264-r1w9a6gc 26 14 2 2 CD cord-007264-r1w9a6gc 26 15 cell cell NN cord-007264-r1w9a6gc 26 16 culture culture NN cord-007264-r1w9a6gc 26 17 flasks flask NNS cord-007264-r1w9a6gc 26 18 ( ( -LRB- cord-007264-r1w9a6gc 26 19 Falcon Falcon NNP cord-007264-r1w9a6gc 26 20 , , , cord-007264-r1w9a6gc 26 21 Oxnard Oxnard NNP cord-007264-r1w9a6gc 26 22 , , , cord-007264-r1w9a6gc 26 23 Calif Calif NNP cord-007264-r1w9a6gc 26 24 ) ) -RRB- cord-007264-r1w9a6gc 26 25 in in IN cord-007264-r1w9a6gc 26 26 Eagle Eagle NNP cord-007264-r1w9a6gc 26 27 's 's POS cord-007264-r1w9a6gc 26 28 MEM mem NN cord-007264-r1w9a6gc 26 29 ( ( -LRB- cord-007264-r1w9a6gc 26 30 EMEM EMEM NNP cord-007264-r1w9a6gc 26 31 ) ) -RRB- cord-007264-r1w9a6gc 26 32 supplemented supplement VBD cord-007264-r1w9a6gc 26 33 with with IN cord-007264-r1w9a6gc 26 34 10010 10010 CD cord-007264-r1w9a6gc 26 35 fetal fetal JJ cord-007264-r1w9a6gc 26 36 bovine bovine JJ cord-007264-r1w9a6gc 26 37 serum serum NN cord-007264-r1w9a6gc 26 38 , , , cord-007264-r1w9a6gc 26 39 penicillin penicillin NN cord-007264-r1w9a6gc 26 40 ( ( -LRB- cord-007264-r1w9a6gc 26 41 100U 100u CD cord-007264-r1w9a6gc 26 42 / / SYM cord-007264-r1w9a6gc 26 43 mL mL NNP cord-007264-r1w9a6gc 26 44 ) ) -RRB- cord-007264-r1w9a6gc 26 45 , , , cord-007264-r1w9a6gc 26 46 and and CC cord-007264-r1w9a6gc 26 47 gentamicin gentamicin NNP cord-007264-r1w9a6gc 26 48 ( ( -LRB- cord-007264-r1w9a6gc 26 49 20 20 CD cord-007264-r1w9a6gc 26 50 J.1g J.1g NNP cord-007264-r1w9a6gc 26 51 / / SYM cord-007264-r1w9a6gc 26 52 mL mL NNP cord-007264-r1w9a6gc 26 53 ) ) -RRB- cord-007264-r1w9a6gc 26 54 . . . cord-007264-r1w9a6gc 27 1 When when WRB cord-007264-r1w9a6gc 27 2 the the DT cord-007264-r1w9a6gc 27 3 cells cell NNS cord-007264-r1w9a6gc 27 4 were be VBD cord-007264-r1w9a6gc 27 5 confluent confluent JJ cord-007264-r1w9a6gc 27 6 , , , cord-007264-r1w9a6gc 27 7 the the DT cord-007264-r1w9a6gc 27 8 growth growth NN cord-007264-r1w9a6gc 27 9 medium medium NN cord-007264-r1w9a6gc 27 10 was be VBD cord-007264-r1w9a6gc 27 11 changed change VBN cord-007264-r1w9a6gc 27 12 to to IN cord-007264-r1w9a6gc 27 13 maintenance maintenance NN cord-007264-r1w9a6gc 27 14 medium medium NN cord-007264-r1w9a6gc 27 15 ( ( -LRB- cord-007264-r1w9a6gc 27 16 EMEM EMEM NNP cord-007264-r1w9a6gc 27 17 with with IN cord-007264-r1w9a6gc 27 18 2 2 CD cord-007264-r1w9a6gc 27 19 % % NN cord-007264-r1w9a6gc 27 20 fetal fetal JJ cord-007264-r1w9a6gc 27 21 bovine bovine JJ cord-007264-r1w9a6gc 27 22 serum serum NN cord-007264-r1w9a6gc 27 23 ) ) -RRB- cord-007264-r1w9a6gc 27 24 ; ; : cord-007264-r1w9a6gc 27 25 cells cell NNS cord-007264-r1w9a6gc 27 26 were be VBD cord-007264-r1w9a6gc 27 27 used use VBN cord-007264-r1w9a6gc 27 28 within within IN cord-007264-r1w9a6gc 27 29 one one CD cord-007264-r1w9a6gc 27 30 week week NN cord-007264-r1w9a6gc 27 31 . . . cord-007264-r1w9a6gc 28 1 All all DT cord-007264-r1w9a6gc 28 2 sera sera NNP cord-007264-r1w9a6gc 28 3 used use VBD cord-007264-r1w9a6gc 28 4 in in IN cord-007264-r1w9a6gc 28 5 the the DT cord-007264-r1w9a6gc 28 6 cellculture cellculture NN cord-007264-r1w9a6gc 28 7 media medium NNS cord-007264-r1w9a6gc 28 8 were be VBD cord-007264-r1w9a6gc 28 9 heat heat NN cord-007264-r1w9a6gc 28 10 - - HYPH cord-007264-r1w9a6gc 28 11 inactivated inactivate VBN cord-007264-r1w9a6gc 28 12 to to TO cord-007264-r1w9a6gc 28 13 remove remove VB cord-007264-r1w9a6gc 28 14 complement complement JJ cord-007264-r1w9a6gc 28 15 activity activity NN cord-007264-r1w9a6gc 28 16 . . . cord-007264-r1w9a6gc 29 1 Before before IN cord-007264-r1w9a6gc 29 2 cells cell NNS cord-007264-r1w9a6gc 29 3 were be VBD cord-007264-r1w9a6gc 29 4 inoculated inoculate VBN cord-007264-r1w9a6gc 29 5 with with IN cord-007264-r1w9a6gc 29 6 virus virus NN cord-007264-r1w9a6gc 29 7 , , , cord-007264-r1w9a6gc 29 8 the the DT cord-007264-r1w9a6gc 29 9 maintenance maintenance NN cord-007264-r1w9a6gc 29 10 medium medium NN cord-007264-r1w9a6gc 29 11 was be VBD cord-007264-r1w9a6gc 29 12 removed remove VBN cord-007264-r1w9a6gc 29 13 , , , cord-007264-r1w9a6gc 29 14 the the DT cord-007264-r1w9a6gc 29 15 cell cell NN cord-007264-r1w9a6gc 29 16 monolayer monolayer NN cord-007264-r1w9a6gc 29 17 was be VBD cord-007264-r1w9a6gc 29 18 washed wash VBN cord-007264-r1w9a6gc 29 19 three three CD cord-007264-r1w9a6gc 29 20 times time NNS cord-007264-r1w9a6gc 29 21 with with IN cord-007264-r1w9a6gc 29 22 PBS PBS NNP cord-007264-r1w9a6gc 29 23 ( ( -LRB- cord-007264-r1w9a6gc 29 24 pH pH NNP cord-007264-r1w9a6gc 29 25 7.4 7.4 CD cord-007264-r1w9a6gc 29 26 ) ) -RRB- cord-007264-r1w9a6gc 29 27 , , , cord-007264-r1w9a6gc 29 28 and and CC cord-007264-r1w9a6gc 29 29 EMEM EMEM NNP cord-007264-r1w9a6gc 29 30 without without IN cord-007264-r1w9a6gc 29 31 serum serum NN cord-007264-r1w9a6gc 29 32 or or CC cord-007264-r1w9a6gc 29 33 antibiotics antibiotic NNS cord-007264-r1w9a6gc 29 34 was be VBD cord-007264-r1w9a6gc 29 35 added add VBN cord-007264-r1w9a6gc 29 36 to to IN cord-007264-r1w9a6gc 29 37 the the DT cord-007264-r1w9a6gc 29 38 flasks flask NNS cord-007264-r1w9a6gc 29 39 . . . cord-007264-r1w9a6gc 30 1 The the DT cord-007264-r1w9a6gc 30 2 cells cell NNS cord-007264-r1w9a6gc 30 3 were be VBD cord-007264-r1w9a6gc 30 4 inoculated inoculate VBN cord-007264-r1w9a6gc 30 5 with with IN cord-007264-r1w9a6gc 30 6 rhinovirus rhinovirus NN cord-007264-r1w9a6gc 30 7 type type NN cord-007264-r1w9a6gc 30 8 39 39 CD cord-007264-r1w9a6gc 30 9 ( ( -LRB- cord-007264-r1w9a6gc 30 10 R39 R39 NNP cord-007264-r1w9a6gc 30 11 ) ) -RRB- cord-007264-r1w9a6gc 30 12 and and CC cord-007264-r1w9a6gc 30 13 incubated incubate VBN cord-007264-r1w9a6gc 30 14 at at IN cord-007264-r1w9a6gc 30 15 33 33 CD cord-007264-r1w9a6gc 30 16 C c NN cord-007264-r1w9a6gc 30 17 in in IN cord-007264-r1w9a6gc 30 18 a a DT cord-007264-r1w9a6gc 30 19 5 5 CD cord-007264-r1w9a6gc 30 20 % % NN cord-007264-r1w9a6gc 30 21 CO co NN cord-007264-r1w9a6gc 30 22 2 2 CD cord-007264-r1w9a6gc 30 23 atmosphere atmosphere NN cord-007264-r1w9a6gc 30 24 . . . cord-007264-r1w9a6gc 31 1 After after IN cord-007264-r1w9a6gc 31 2 48 48 CD cord-007264-r1w9a6gc 31 3 h h NN cord-007264-r1w9a6gc 31 4 , , , cord-007264-r1w9a6gc 31 5 when when WRB cord-007264-r1w9a6gc 31 6 cpe cpe NNP cord-007264-r1w9a6gc 31 7 was be VBD cord-007264-r1w9a6gc 31 8 seen see VBN cord-007264-r1w9a6gc 31 9 in in IN cord-007264-r1w9a6gc 31 10 " " `` cord-007264-r1w9a6gc 31 11 ' ' `` cord-007264-r1w9a6gc 31 12 80 80 CD cord-007264-r1w9a6gc 31 13 % % NN cord-007264-r1w9a6gc 31 14 of of IN cord-007264-r1w9a6gc 31 15 the the DT cord-007264-r1w9a6gc 31 16 monolayer monolayer NN cord-007264-r1w9a6gc 31 17 , , , cord-007264-r1w9a6gc 31 18 the the DT cord-007264-r1w9a6gc 31 19 medium medium NN cord-007264-r1w9a6gc 31 20 was be VBD cord-007264-r1w9a6gc 31 21 collected collect VBN cord-007264-r1w9a6gc 31 22 from from IN cord-007264-r1w9a6gc 31 23 the the DT cord-007264-r1w9a6gc 31 24 infected infected JJ cord-007264-r1w9a6gc 31 25 cultures culture NNS cord-007264-r1w9a6gc 31 26 . . . cord-007264-r1w9a6gc 32 1 Cell cell NN cord-007264-r1w9a6gc 32 2 monolayers monolayer NNS cord-007264-r1w9a6gc 32 3 handled handle VBD cord-007264-r1w9a6gc 32 4 in in IN cord-007264-r1w9a6gc 32 5 an an DT cord-007264-r1w9a6gc 32 6 identical identical JJ cord-007264-r1w9a6gc 32 7 fashion fashion NN cord-007264-r1w9a6gc 32 8 , , , cord-007264-r1w9a6gc 32 9 except except IN cord-007264-r1w9a6gc 32 10 that that IN cord-007264-r1w9a6gc 32 11 they -PRON- PRP cord-007264-r1w9a6gc 32 12 were be VBD cord-007264-r1w9a6gc 32 13 sham sham JJ cord-007264-r1w9a6gc 32 14 inoculated inoculate VBN cord-007264-r1w9a6gc 32 15 with with IN cord-007264-r1w9a6gc 32 16 the the DT cord-007264-r1w9a6gc 32 17 diluent diluent NN cord-007264-r1w9a6gc 32 18 for for IN cord-007264-r1w9a6gc 32 19 the the DT cord-007264-r1w9a6gc 32 20 virus virus NN cord-007264-r1w9a6gc 32 21 inoculum inoculum NN cord-007264-r1w9a6gc 32 22 ( ( -LRB- cord-007264-r1w9a6gc 32 23 serum serum NN cord-007264-r1w9a6gc 32 24 - - HYPH cord-007264-r1w9a6gc 32 25 free free JJ cord-007264-r1w9a6gc 32 26 medium medium NN cord-007264-r1w9a6gc 32 27 ) ) -RRB- cord-007264-r1w9a6gc 32 28 instead instead RB cord-007264-r1w9a6gc 32 29 of of IN cord-007264-r1w9a6gc 32 30 R39 R39 NNP cord-007264-r1w9a6gc 32 31 , , , cord-007264-r1w9a6gc 32 32 were be VBD cord-007264-r1w9a6gc 32 33 used use VBN cord-007264-r1w9a6gc 32 34 as as IN cord-007264-r1w9a6gc 32 35 uninfected uninfected JJ cord-007264-r1w9a6gc 32 36 controls control NNS cord-007264-r1w9a6gc 32 37 . . . cord-007264-r1w9a6gc 33 1 The the DT cord-007264-r1w9a6gc 33 2 media medium NNS cord-007264-r1w9a6gc 33 3 harvested harvest VBN cord-007264-r1w9a6gc 33 4 from from IN cord-007264-r1w9a6gc 33 5 the the DT cord-007264-r1w9a6gc 33 6 infected infected JJ cord-007264-r1w9a6gc 33 7 cells cell NNS cord-007264-r1w9a6gc 33 8 and and CC cord-007264-r1w9a6gc 33 9 the the DT cord-007264-r1w9a6gc 33 10 uninfected uninfected JJ cord-007264-r1w9a6gc 33 11 cells cell NNS cord-007264-r1w9a6gc 33 12 were be VBD cord-007264-r1w9a6gc 33 13 centrifuged centrifuge VBN cord-007264-r1w9a6gc 33 14 at at IN cord-007264-r1w9a6gc 33 15 low low JJ cord-007264-r1w9a6gc 33 16 speed speed NN cord-007264-r1w9a6gc 33 17 ( ( -LRB- cord-007264-r1w9a6gc 33 18 225 225 CD cord-007264-r1w9a6gc 33 19 g g NN cord-007264-r1w9a6gc 33 20 ) ) -RRB- cord-007264-r1w9a6gc 33 21 in in IN cord-007264-r1w9a6gc 33 22 a a DT cord-007264-r1w9a6gc 33 23 TJ-6 TJ-6 NNP cord-007264-r1w9a6gc 33 24 centrifuge centrifuge NN cord-007264-r1w9a6gc 33 25 ( ( -LRB- cord-007264-r1w9a6gc 33 26 Beckman Beckman NNP cord-007264-r1w9a6gc 33 27 , , , cord-007264-r1w9a6gc 33 28 Palo Palo NNP cord-007264-r1w9a6gc 33 29 Alto Alto NNP cord-007264-r1w9a6gc 33 30 , , , cord-007264-r1w9a6gc 33 31 Calif Calif NNP cord-007264-r1w9a6gc 33 32 ) ) -RRB- cord-007264-r1w9a6gc 33 33 to to TO cord-007264-r1w9a6gc 33 34 remove remove VB cord-007264-r1w9a6gc 33 35 cell cell NN cord-007264-r1w9a6gc 33 36 debris debris NN cord-007264-r1w9a6gc 33 37 ; ; : cord-007264-r1w9a6gc 33 38 they -PRON- PRP cord-007264-r1w9a6gc 33 39 were be VBD cord-007264-r1w9a6gc 33 40 then then RB cord-007264-r1w9a6gc 33 41 assayed assay VBN cord-007264-r1w9a6gc 33 42 for for IN cord-007264-r1w9a6gc 33 43 chemoattractant chemoattractant NN cord-007264-r1w9a6gc 33 44 activity activity NN cord-007264-r1w9a6gc 33 45 . . . cord-007264-r1w9a6gc 34 1 The the DT cord-007264-r1w9a6gc 34 2 experiments experiment NNS cord-007264-r1w9a6gc 34 3 in in IN cord-007264-r1w9a6gc 34 4 HeLa HeLa NNP cord-007264-r1w9a6gc 34 5 cells cell NNS cord-007264-r1w9a6gc 34 6 were be VBD cord-007264-r1w9a6gc 34 7 done do VBN cord-007264-r1w9a6gc 34 8 by by IN cord-007264-r1w9a6gc 34 9 using use VBG cord-007264-r1w9a6gc 34 10 a a DT cord-007264-r1w9a6gc 34 11 rhinovirus rhinovirus NN cord-007264-r1w9a6gc 34 12 - - HYPH cord-007264-r1w9a6gc 34 13 sensitive sensitive JJ cord-007264-r1w9a6gc 34 14 HeLa HeLa NNP cord-007264-r1w9a6gc 34 15 cell cell NN cord-007264-r1w9a6gc 34 16 line line NN cord-007264-r1w9a6gc 34 17 . . . cord-007264-r1w9a6gc 35 1 We -PRON- PRP cord-007264-r1w9a6gc 35 2 used use VBD cord-007264-r1w9a6gc 35 3 McCoy McCoy NNP cord-007264-r1w9a6gc 35 4 's 's POS cord-007264-r1w9a6gc 35 5 medium medium NN cord-007264-r1w9a6gc 35 6 ( ( -LRB- cord-007264-r1w9a6gc 35 7 Whitaker Whitaker NNP cord-007264-r1w9a6gc 35 8 M.A. M.A. NNP cord-007264-r1w9a6gc 35 9 Bioproducts Bioproducts NNP cord-007264-r1w9a6gc 35 10 , , , cord-007264-r1w9a6gc 35 11 Walkersville Walkersville NNP cord-007264-r1w9a6gc 35 12 , , , cord-007264-r1w9a6gc 35 13 Md Md NNP cord-007264-r1w9a6gc 35 14 ) ) -RRB- cord-007264-r1w9a6gc 35 15 supplemented supplement VBD cord-007264-r1w9a6gc 35 16 with with IN cord-007264-r1w9a6gc 35 17 10070 10070 CD cord-007264-r1w9a6gc 35 18 and and CC cord-007264-r1w9a6gc 35 19 2 2 CD cord-007264-r1w9a6gc 35 20 % % NN cord-007264-r1w9a6gc 35 21 fetal fetal JJ cord-007264-r1w9a6gc 35 22 bovine bovine JJ cord-007264-r1w9a6gc 35 23 serum serum NN cord-007264-r1w9a6gc 35 24 as as IN cord-007264-r1w9a6gc 35 25 the the DT cord-007264-r1w9a6gc 35 26 growth growth NN cord-007264-r1w9a6gc 35 27 medium medium NN cord-007264-r1w9a6gc 35 28 and and CC cord-007264-r1w9a6gc 35 29 maintenance maintenance NN cord-007264-r1w9a6gc 35 30 medium medium NN cord-007264-r1w9a6gc 35 31 , , , cord-007264-r1w9a6gc 35 32 respectively respectively RB cord-007264-r1w9a6gc 35 33 . . . cord-007264-r1w9a6gc 36 1 Titrations titration NNS cord-007264-r1w9a6gc 36 2 of of IN cord-007264-r1w9a6gc 36 3 virus virus NN cord-007264-r1w9a6gc 36 4 . . . cord-007264-r1w9a6gc 37 1 All all DT cord-007264-r1w9a6gc 37 2 titrations titration NNS cord-007264-r1w9a6gc 37 3 of of IN cord-007264-r1w9a6gc 37 4 virus virus NN cord-007264-r1w9a6gc 37 5 were be VBD cord-007264-r1w9a6gc 37 6 done do VBN cord-007264-r1w9a6gc 37 7 in in IN cord-007264-r1w9a6gc 37 8 96-well 96-well CD cord-007264-r1w9a6gc 37 9 microtiter microtiter NN cord-007264-r1w9a6gc 37 10 plates plate NNS cord-007264-r1w9a6gc 37 11 ( ( -LRB- cord-007264-r1w9a6gc 37 12 Falcon Falcon NNP cord-007264-r1w9a6gc 37 13 ) ) -RRB- cord-007264-r1w9a6gc 37 14 . . . cord-007264-r1w9a6gc 38 1 Serial serial JJ cord-007264-r1w9a6gc 38 2 10fold 10fold CD cord-007264-r1w9a6gc 38 3 dilutions dilution NNS cord-007264-r1w9a6gc 38 4 of of IN cord-007264-r1w9a6gc 38 5 each each DT cord-007264-r1w9a6gc 38 6 specimen specimen NN cord-007264-r1w9a6gc 38 7 were be VBD cord-007264-r1w9a6gc 38 8 made make VBN cord-007264-r1w9a6gc 38 9 , , , cord-007264-r1w9a6gc 38 10 and and CC cord-007264-r1w9a6gc 38 11 2 2 CD cord-007264-r1w9a6gc 38 12 x x SYM cord-007264-r1w9a6gc 38 13 10 10 CD cord-007264-r1w9a6gc 38 14 4 4 CD cord-007264-r1w9a6gc 38 15 HeLa HeLa NNP cord-007264-r1w9a6gc 38 16 cells cell NNS cord-007264-r1w9a6gc 38 17 were be VBD cord-007264-r1w9a6gc 38 18 added add VBN cord-007264-r1w9a6gc 38 19 to to IN cord-007264-r1w9a6gc 38 20 each each DT cord-007264-r1w9a6gc 38 21 well well RB cord-007264-r1w9a6gc 38 22 . . . cord-007264-r1w9a6gc 39 1 The the DT cord-007264-r1w9a6gc 39 2 plates plate NNS cord-007264-r1w9a6gc 39 3 were be VBD cord-007264-r1w9a6gc 39 4 incubated incubate VBN cord-007264-r1w9a6gc 39 5 at at IN cord-007264-r1w9a6gc 39 6 33 33 CD cord-007264-r1w9a6gc 39 7 C c NN cord-007264-r1w9a6gc 39 8 for for IN cord-007264-r1w9a6gc 39 9 seven seven CD cord-007264-r1w9a6gc 39 10 days day NNS cord-007264-r1w9a6gc 39 11 and and CC cord-007264-r1w9a6gc 39 12 then then RB cord-007264-r1w9a6gc 39 13 examined examine VBD cord-007264-r1w9a6gc 39 14 for for IN cord-007264-r1w9a6gc 39 15 viral viral JJ cord-007264-r1w9a6gc 39 16 cpe cpe NNP cord-007264-r1w9a6gc 39 17 . . . cord-007264-r1w9a6gc 40 1 The the DT cord-007264-r1w9a6gc 40 2 titers titer NNS cord-007264-r1w9a6gc 40 3 of of IN cord-007264-r1w9a6gc 40 4 virus virus NN cord-007264-r1w9a6gc 40 5 were be VBD cord-007264-r1w9a6gc 40 6 calculated calculate VBN cord-007264-r1w9a6gc 40 7 by by IN cord-007264-r1w9a6gc 40 8 the the DT cord-007264-r1w9a6gc 40 9 method method NN cord-007264-r1w9a6gc 40 10 of of IN cord-007264-r1w9a6gc 40 11 Reed Reed NNP cord-007264-r1w9a6gc 40 12 and and CC cord-007264-r1w9a6gc 40 13 Muench Muench NNP cord-007264-r1w9a6gc 40 14 [ [ -LRB- cord-007264-r1w9a6gc 40 15 9 9 CD cord-007264-r1w9a6gc 40 16 ] ] -RRB- cord-007264-r1w9a6gc 40 17 . . . cord-007264-r1w9a6gc 41 1 Chemotaxis Chemotaxis NNP cord-007264-r1w9a6gc 41 2 assays assay NNS cord-007264-r1w9a6gc 41 3 . . . cord-007264-r1w9a6gc 42 1 PMNLs pmnl NNS cord-007264-r1w9a6gc 42 2 were be VBD cord-007264-r1w9a6gc 42 3 collected collect VBN cord-007264-r1w9a6gc 42 4 from from IN cord-007264-r1w9a6gc 42 5 the the DT cord-007264-r1w9a6gc 42 6 peripheral peripheral JJ cord-007264-r1w9a6gc 42 7 blood blood NN cord-007264-r1w9a6gc 42 8 of of IN cord-007264-r1w9a6gc 42 9 normal normal JJ cord-007264-r1w9a6gc 42 10 young young JJ cord-007264-r1w9a6gc 42 11 adult adult NN cord-007264-r1w9a6gc 42 12 volunteers volunteer NNS cord-007264-r1w9a6gc 42 13 by by IN cord-007264-r1w9a6gc 42 14 sedimentation sedimentation NN cord-007264-r1w9a6gc 42 15 in in IN cord-007264-r1w9a6gc 42 16 2 2 CD cord-007264-r1w9a6gc 42 17 % % NN cord-007264-r1w9a6gc 42 18 dextran dextran NN cord-007264-r1w9a6gc 42 19 70 70 CD cord-007264-r1w9a6gc 43 1 ( ( -LRB- cord-007264-r1w9a6gc 43 2 McGaw McGaw NNP cord-007264-r1w9a6gc 43 3 Laboratories Laboratories NNPS cord-007264-r1w9a6gc 43 4 , , , cord-007264-r1w9a6gc 43 5 Irving Irving NNP cord-007264-r1w9a6gc 43 6 , , , cord-007264-r1w9a6gc 43 7 Calif Calif NNP cord-007264-r1w9a6gc 43 8 ) ) -RRB- cord-007264-r1w9a6gc 43 9 followed follow VBD cord-007264-r1w9a6gc 43 10 by by IN cord-007264-r1w9a6gc 43 11 centrifugation centrifugation NN cord-007264-r1w9a6gc 43 12 with with IN cord-007264-r1w9a6gc 43 13 Ficoll Ficoll NNP cord-007264-r1w9a6gc 43 14 - - HYPH cord-007264-r1w9a6gc 43 15 Paque Paque NNP cord-007264-r1w9a6gc 44 1 ® ® LS cord-007264-r1w9a6gc 44 2 ( ( -LRB- cord-007264-r1w9a6gc 44 3 Pharmacia Pharmacia NNP cord-007264-r1w9a6gc 44 4 , , , cord-007264-r1w9a6gc 44 5 Piscataway Piscataway NNP cord-007264-r1w9a6gc 44 6 , , , cord-007264-r1w9a6gc 44 7 NJ NJ NNP cord-007264-r1w9a6gc 44 8 ) ) -RRB- cord-007264-r1w9a6gc 44 9 . . . cord-007264-r1w9a6gc 45 1 The the DT cord-007264-r1w9a6gc 45 2 PMNLs pmnl NNS cord-007264-r1w9a6gc 45 3 were be VBD cord-007264-r1w9a6gc 45 4 then then RB cord-007264-r1w9a6gc 45 5 counted count VBN cord-007264-r1w9a6gc 45 6 and and CC cord-007264-r1w9a6gc 45 7 diluted dilute VBN cord-007264-r1w9a6gc 45 8 to to IN cord-007264-r1w9a6gc 45 9 2 2 CD cord-007264-r1w9a6gc 45 10 x x SYM cord-007264-r1w9a6gc 45 11 10 10 CD cord-007264-r1w9a6gc 45 12 6 6 CD cord-007264-r1w9a6gc 45 13 cells cell NNS cord-007264-r1w9a6gc 45 14 / / SYM cord-007264-r1w9a6gc 45 15 mL ml NN cord-007264-r1w9a6gc 45 16 in in IN cord-007264-r1w9a6gc 45 17 HEPES HEPES NNP cord-007264-r1w9a6gc 45 18 buffer buffer NN cord-007264-r1w9a6gc 45 19 with with IN cord-007264-r1w9a6gc 45 20 I -PRON- PRP cord-007264-r1w9a6gc 45 21 % % NN cord-007264-r1w9a6gc 45 22 bovine bovine JJ cord-007264-r1w9a6gc 45 23 serum serum NN cord-007264-r1w9a6gc 45 24 albumin albumin NN cord-007264-r1w9a6gc 45 25 ( ( -LRB- cord-007264-r1w9a6gc 45 26 Fraction fraction NN cord-007264-r1w9a6gc 45 27 V V NNP cord-007264-r1w9a6gc 45 28 powder powder NN cord-007264-r1w9a6gc 45 29 ; ; : cord-007264-r1w9a6gc 45 30 Sigma Sigma NNP cord-007264-r1w9a6gc 45 31 , , , cord-007264-r1w9a6gc 45 32 St. St. NNP cord-007264-r1w9a6gc 45 33 Louis Louis NNP cord-007264-r1w9a6gc 45 34 ) ) -RRB- cord-007264-r1w9a6gc 45 35 . . . cord-007264-r1w9a6gc 46 1 Chemotaxis chemotaxis NN cord-007264-r1w9a6gc 46 2 assays assay NNS cord-007264-r1w9a6gc 46 3 were be VBD cord-007264-r1w9a6gc 46 4 done do VBN cord-007264-r1w9a6gc 46 5 by by IN cord-007264-r1w9a6gc 46 6 using use VBG cord-007264-r1w9a6gc 46 7 a a DT cord-007264-r1w9a6gc 46 8 48-well 48-well CD cord-007264-r1w9a6gc 46 9 microchemotaxis microchemotaxis NNP cord-007264-r1w9a6gc 46 10 chamber chamber NN cord-007264-r1w9a6gc 46 11 ( ( -LRB- cord-007264-r1w9a6gc 46 12 Neuroprobe Neuroprobe NNP cord-007264-r1w9a6gc 46 13 , , , cord-007264-r1w9a6gc 46 14 Cabin Cabin NNP cord-007264-r1w9a6gc 46 15 John John NNP cord-007264-r1w9a6gc 46 16 , , , cord-007264-r1w9a6gc 46 17 Md Md NNP cord-007264-r1w9a6gc 46 18 ) ) -RRB- cord-007264-r1w9a6gc 46 19 . . . cord-007264-r1w9a6gc 47 1 Each each DT cord-007264-r1w9a6gc 47 2 of of IN cord-007264-r1w9a6gc 47 3 eight eight CD cord-007264-r1w9a6gc 47 4 specimens specimen NNS cord-007264-r1w9a6gc 47 5 to to TO cord-007264-r1w9a6gc 47 6 be be VB cord-007264-r1w9a6gc 47 7 assayed assay VBN cord-007264-r1w9a6gc 47 8 for for IN cord-007264-r1w9a6gc 47 9 chemoattractant chemoattractant NN cord-007264-r1w9a6gc 47 10 activity activity NN cord-007264-r1w9a6gc 47 11 was be VBD cord-007264-r1w9a6gc 47 12 placed place VBN cord-007264-r1w9a6gc 47 13 into into IN cord-007264-r1w9a6gc 47 14 four four CD cord-007264-r1w9a6gc 47 15 of of IN cord-007264-r1w9a6gc 47 16 the the DT cord-007264-r1w9a6gc 47 17 bottom bottom JJ cord-007264-r1w9a6gc 47 18 wells well NNS cord-007264-r1w9a6gc 47 19 of of IN cord-007264-r1w9a6gc 47 20 the the DT cord-007264-r1w9a6gc 47 21 chamber chamber NN cord-007264-r1w9a6gc 47 22 . . . cord-007264-r1w9a6gc 48 1 Cell cell NN cord-007264-r1w9a6gc 48 2 culture culture NN cord-007264-r1w9a6gc 48 3 medium medium NN cord-007264-r1w9a6gc 48 4 that that WDT cord-007264-r1w9a6gc 48 5 had have VBD cord-007264-r1w9a6gc 48 6 been be VBN cord-007264-r1w9a6gc 48 7 incubated incubate VBN cord-007264-r1w9a6gc 48 8 with with IN cord-007264-r1w9a6gc 48 9 neither neither DT cord-007264-r1w9a6gc 48 10 cells cell NNS cord-007264-r1w9a6gc 48 11 nor nor CC cord-007264-r1w9a6gc 48 12 virus virus NN cord-007264-r1w9a6gc 48 13 was be VBD cord-007264-r1w9a6gc 48 14 included include VBN cord-007264-r1w9a6gc 48 15 as as IN cord-007264-r1w9a6gc 48 16 a a DT cord-007264-r1w9a6gc 48 17 negative negative JJ cord-007264-r1w9a6gc 48 18 control control NN cord-007264-r1w9a6gc 48 19 . . . cord-007264-r1w9a6gc 49 1 Either either CC cord-007264-r1w9a6gc 49 2 10 10 CD cord-007264-r1w9a6gc 49 3 - - SYM cord-007264-r1w9a6gc 49 4 8 8 CD cord-007264-r1w9a6gc 49 5 M M NNP cord-007264-r1w9a6gc 49 6 N N NNP cord-007264-r1w9a6gc 49 7 - - HYPH cord-007264-r1w9a6gc 49 8 formyl formyl NNP cord-007264-r1w9a6gc 49 9 - - HYPH cord-007264-r1w9a6gc 49 10 tmethionyl tmethionyl NNP cord-007264-r1w9a6gc 49 11 - - HYPH cord-007264-r1w9a6gc 49 12 i i NN cord-007264-r1w9a6gc 49 13 - - HYPH cord-007264-r1w9a6gc 49 14 leucyl leucyl NNP cord-007264-r1w9a6gc 49 15 - - HYPH cord-007264-r1w9a6gc 49 16 i i NN cord-007264-r1w9a6gc 49 17 - - HYPH cord-007264-r1w9a6gc 49 18 phenylalanine phenylalanine NN cord-007264-r1w9a6gc 49 19 ( ( -LRB- cord-007264-r1w9a6gc 49 20 FMLP FMLP NNP cord-007264-r1w9a6gc 49 21 ; ; : cord-007264-r1w9a6gc 49 22 Sigma Sigma NNP cord-007264-r1w9a6gc 49 23 ) ) -RRB- cord-007264-r1w9a6gc 49 24 or or CC cord-007264-r1w9a6gc 49 25 10 10 CD cord-007264-r1w9a6gc 49 26 % % NN cord-007264-r1w9a6gc 49 27 zymosan zymosan NN cord-007264-r1w9a6gc 49 28 - - HYPH cord-007264-r1w9a6gc 49 29 activated activate VBN cord-007264-r1w9a6gc 49 30 serum serum NN cord-007264-r1w9a6gc 49 31 prepared prepare VBN cord-007264-r1w9a6gc 49 32 as as IN cord-007264-r1w9a6gc 49 33 described describe VBN cord-007264-r1w9a6gc 49 34 previously previously RB cord-007264-r1w9a6gc 49 35 [ [ -LRB- cord-007264-r1w9a6gc 49 36 10 10 CD cord-007264-r1w9a6gc 49 37 ] ] -RRB- cord-007264-r1w9a6gc 49 38 was be VBD cord-007264-r1w9a6gc 49 39 included include VBN cord-007264-r1w9a6gc 49 40 as as IN cord-007264-r1w9a6gc 49 41 a a DT cord-007264-r1w9a6gc 49 42 positive positive JJ cord-007264-r1w9a6gc 49 43 control control NN cord-007264-r1w9a6gc 49 44 for for IN cord-007264-r1w9a6gc 49 45 each each DT cord-007264-r1w9a6gc 49 46 experiment experiment NN cord-007264-r1w9a6gc 49 47 . . . cord-007264-r1w9a6gc 50 1 After after IN cord-007264-r1w9a6gc 50 2 placing place VBG cord-007264-r1w9a6gc 50 3 30 30 CD cord-007264-r1w9a6gc 50 4 ul ul NN cord-007264-r1w9a6gc 50 5 , , , cord-007264-r1w9a6gc 50 6 of of IN cord-007264-r1w9a6gc 50 7 the the DT cord-007264-r1w9a6gc 50 8 material material NN cord-007264-r1w9a6gc 50 9 to to TO cord-007264-r1w9a6gc 50 10 be be VB cord-007264-r1w9a6gc 50 11 assayed assay VBN cord-007264-r1w9a6gc 50 12 into into IN cord-007264-r1w9a6gc 50 13 each each DT cord-007264-r1w9a6gc 50 14 of of IN cord-007264-r1w9a6gc 50 15 the the DT cord-007264-r1w9a6gc 50 16 bottom bottom JJ cord-007264-r1w9a6gc 50 17 wells well NNS cord-007264-r1w9a6gc 50 18 , , , cord-007264-r1w9a6gc 50 19 we -PRON- PRP cord-007264-r1w9a6gc 50 20 covered cover VBD cord-007264-r1w9a6gc 50 21 the the DT cord-007264-r1w9a6gc 50 22 wells well NNS cord-007264-r1w9a6gc 50 23 with with IN cord-007264-r1w9a6gc 50 24 a a DT cord-007264-r1w9a6gc 50 25 5-llm 5-llm CD cord-007264-r1w9a6gc 50 26 filter filter NN cord-007264-r1w9a6gc 50 27 ( ( -LRB- cord-007264-r1w9a6gc 50 28 Millipore Millipore NNP cord-007264-r1w9a6gc 50 29 , , , cord-007264-r1w9a6gc 50 30 Bedford Bedford NNP cord-007264-r1w9a6gc 50 31 , , , cord-007264-r1w9a6gc 50 32 Mass Mass NNP cord-007264-r1w9a6gc 50 33 ) ) -RRB- cord-007264-r1w9a6gc 50 34 and and CC cord-007264-r1w9a6gc 50 35 placed place VBD cord-007264-r1w9a6gc 50 36 50 50 CD cord-007264-r1w9a6gc 50 37 ul ul NN cord-007264-r1w9a6gc 50 38 , , , cord-007264-r1w9a6gc 50 39 of of IN cord-007264-r1w9a6gc 50 40 the the DT cord-007264-r1w9a6gc 50 41 diluted diluted JJ cord-007264-r1w9a6gc 50 42 PMNLs pmnl NNS cord-007264-r1w9a6gc 50 43 in in IN cord-007264-r1w9a6gc 50 44 the the DT cord-007264-r1w9a6gc 50 45 top top JJ cord-007264-r1w9a6gc 50 46 portion portion NN cord-007264-r1w9a6gc 50 47 of of IN cord-007264-r1w9a6gc 50 48 each each DT cord-007264-r1w9a6gc 50 49 well well NN cord-007264-r1w9a6gc 50 50 . . . cord-007264-r1w9a6gc 51 1 The the DT cord-007264-r1w9a6gc 51 2 chamber chamber NN cord-007264-r1w9a6gc 51 3 was be VBD cord-007264-r1w9a6gc 51 4 incubated incubate VBN cord-007264-r1w9a6gc 51 5 at at IN cord-007264-r1w9a6gc 51 6 37 37 CD cord-007264-r1w9a6gc 51 7 C c NN cord-007264-r1w9a6gc 51 8 for for IN cord-007264-r1w9a6gc 51 9 90 90 CD cord-007264-r1w9a6gc 51 10 min min NN cord-007264-r1w9a6gc 51 11 in in IN cord-007264-r1w9a6gc 51 12 a a DT cord-007264-r1w9a6gc 51 13 5 5 CD cord-007264-r1w9a6gc 51 14 % % NN cord-007264-r1w9a6gc 51 15 CO2 co2 NN cord-007264-r1w9a6gc 51 16 atmosphere atmosphere NN cord-007264-r1w9a6gc 51 17 , , , cord-007264-r1w9a6gc 51 18 and and CC cord-007264-r1w9a6gc 51 19 the the DT cord-007264-r1w9a6gc 51 20 filter filter NN cord-007264-r1w9a6gc 51 21 was be VBD cord-007264-r1w9a6gc 51 22 fixed fix VBN cord-007264-r1w9a6gc 51 23 in in IN cord-007264-r1w9a6gc 51 24 methanol methanol NN cord-007264-r1w9a6gc 51 25 and and CC cord-007264-r1w9a6gc 51 26 stained stain VBN cord-007264-r1w9a6gc 51 27 with with IN cord-007264-r1w9a6gc 51 28 hematoxylin hematoxylin JJ cord-007264-r1w9a6gc 51 29 stain stain NN cord-007264-r1w9a6gc 51 30 . . . cord-007264-r1w9a6gc 52 1 The the DT cord-007264-r1w9a6gc 52 2 cellsthat cellsthat NN cord-007264-r1w9a6gc 52 3 had have VBD cord-007264-r1w9a6gc 52 4 migrated migrate VBN cord-007264-r1w9a6gc 52 5 through through IN cord-007264-r1w9a6gc 52 6 the the DT cord-007264-r1w9a6gc 52 7 filter filter NN cord-007264-r1w9a6gc 52 8 were be VBD cord-007264-r1w9a6gc 52 9 counted count VBN cord-007264-r1w9a6gc 52 10 in in IN cord-007264-r1w9a6gc 52 11 10 10 CD cord-007264-r1w9a6gc 52 12 random random JJ cord-007264-r1w9a6gc 52 13 fields field NNS cord-007264-r1w9a6gc 52 14 by by IN cord-007264-r1w9a6gc 52 15 using use VBG cord-007264-r1w9a6gc 52 16 a a DT cord-007264-r1w9a6gc 52 17 5 5 CD cord-007264-r1w9a6gc 52 18 x x SYM cord-007264-r1w9a6gc 52 19 5-mm 5-mm CD cord-007264-r1w9a6gc 52 20 photographic photographic JJ cord-007264-r1w9a6gc 52 21 reticle reticle NN cord-007264-r1w9a6gc 52 22 at at IN cord-007264-r1w9a6gc 52 23 a a DT cord-007264-r1w9a6gc 52 24 magnification magnification NN cord-007264-r1w9a6gc 52 25 of of IN cord-007264-r1w9a6gc 52 26 x x SYM cord-007264-r1w9a6gc 52 27 450 450 CD cord-007264-r1w9a6gc 52 28 ( ( -LRB- cord-007264-r1w9a6gc 52 29 high high JJ cord-007264-r1w9a6gc 52 30 - - HYPH cord-007264-r1w9a6gc 52 31 power power NN cord-007264-r1w9a6gc 52 32 field field NN cord-007264-r1w9a6gc 52 33 ; ; : cord-007264-r1w9a6gc 52 34 hpf hpf NNP cord-007264-r1w9a6gc 52 35 ) ) -RRB- cord-007264-r1w9a6gc 52 36 . . . cord-007264-r1w9a6gc 53 1 Experiments experiment NNS cord-007264-r1w9a6gc 53 2 in in IN cord-007264-r1w9a6gc 53 3 which which WDT cord-007264-r1w9a6gc 53 4 the the DT cord-007264-r1w9a6gc 53 5 mean mean JJ cord-007264-r1w9a6gc 53 6 cell cell NN cord-007264-r1w9a6gc 53 7 count count NN cord-007264-r1w9a6gc 53 8 in in IN cord-007264-r1w9a6gc 53 9 the the DT cord-007264-r1w9a6gc 53 10 negative negative JJ cord-007264-r1w9a6gc 53 11 control control NN cord-007264-r1w9a6gc 53 12 wells well NNS cord-007264-r1w9a6gc 53 13 was be VBD cord-007264-r1w9a6gc 53 14 greater great JJR cord-007264-r1w9a6gc 53 15 than than IN cord-007264-r1w9a6gc 53 16 15 15 CD cord-007264-r1w9a6gc 53 17 per per IN cord-007264-r1w9a6gc 53 18 10 10 CD cord-007264-r1w9a6gc 53 19 hpf hpf NN cord-007264-r1w9a6gc 53 20 or or CC cord-007264-r1w9a6gc 53 21 in in IN cord-007264-r1w9a6gc 53 22 which which WDT cord-007264-r1w9a6gc 53 23 the the DT cord-007264-r1w9a6gc 53 24 mean mean JJ cord-007264-r1w9a6gc 53 25 counts count VBZ cord-007264-r1w9a6gc 53 26 for for IN cord-007264-r1w9a6gc 53 27 the the DT cord-007264-r1w9a6gc 53 28 positive positive JJ cord-007264-r1w9a6gc 53 29 control control NN cord-007264-r1w9a6gc 53 30 were be VBD cord-007264-r1w9a6gc 53 31 less less JJR cord-007264-r1w9a6gc 53 32 than than IN cord-007264-r1w9a6gc 53 33 five five CD cord-007264-r1w9a6gc 53 34 times time NNS cord-007264-r1w9a6gc 53 35 those those DT cord-007264-r1w9a6gc 53 36 of of IN cord-007264-r1w9a6gc 53 37 the the DT cord-007264-r1w9a6gc 53 38 negative negative JJ cord-007264-r1w9a6gc 53 39 control control NN cord-007264-r1w9a6gc 53 40 were be VBD cord-007264-r1w9a6gc 53 41 excluded exclude VBN cord-007264-r1w9a6gc 53 42 from from IN cord-007264-r1w9a6gc 53 43 analysis analysis NN cord-007264-r1w9a6gc 53 44 . . . cord-007264-r1w9a6gc 54 1 Approximately approximately RB cord-007264-r1w9a6gc 54 2 10 10 CD cord-007264-r1w9a6gc 54 3 % % NN cord-007264-r1w9a6gc 54 4 of of IN cord-007264-r1w9a6gc 54 5 the the DT cord-007264-r1w9a6gc 54 6 experiments experiment NNS cord-007264-r1w9a6gc 54 7 were be VBD cord-007264-r1w9a6gc 54 8 excluded exclude VBN cord-007264-r1w9a6gc 54 9 by by IN cord-007264-r1w9a6gc 54 10 these these DT cord-007264-r1w9a6gc 54 11 criteria criterion NNS cord-007264-r1w9a6gc 54 12 . . . cord-007264-r1w9a6gc 55 1 Time time NN cord-007264-r1w9a6gc 55 2 course course NN cord-007264-r1w9a6gc 55 3 ofelaboration ofelaboration NN cord-007264-r1w9a6gc 55 4 . . . cord-007264-r1w9a6gc 56 1 The the DT cord-007264-r1w9a6gc 56 2 elaboration elaboration NN cord-007264-r1w9a6gc 56 3 of of IN cord-007264-r1w9a6gc 56 4 the the DT cord-007264-r1w9a6gc 56 5 chemoattractant chemoattractant NN cord-007264-r1w9a6gc 56 6 relative relative NN cord-007264-r1w9a6gc 56 7 to to IN cord-007264-r1w9a6gc 56 8 the the DT cord-007264-r1w9a6gc 56 9 time time NN cord-007264-r1w9a6gc 56 10 of of IN cord-007264-r1w9a6gc 56 11 viral viral JJ cord-007264-r1w9a6gc 56 12 infection infection NN cord-007264-r1w9a6gc 56 13 was be VBD cord-007264-r1w9a6gc 56 14 determined determine VBN cord-007264-r1w9a6gc 56 15 by by IN cord-007264-r1w9a6gc 56 16 infecting infect VBG cord-007264-r1w9a6gc 56 17 MRC-5 MRC-5 NNP cord-007264-r1w9a6gc 56 18 cells cell NNS cord-007264-r1w9a6gc 56 19 with with IN cord-007264-r1w9a6gc 56 20 R39 R39 NNP cord-007264-r1w9a6gc 56 21 at at IN cord-007264-r1w9a6gc 56 22 an an DT cord-007264-r1w9a6gc 56 23 moi moi NN cord-007264-r1w9a6gc 56 24 of of IN cord-007264-r1w9a6gc 56 25 0.01 0.01 CD cord-007264-r1w9a6gc 56 26 TCID TCID NNS cord-007264-r1w9a6gc 56 27 so so RB cord-007264-r1w9a6gc 56 28 per per IN cord-007264-r1w9a6gc 56 29 cell cell NN cord-007264-r1w9a6gc 56 30 . . . cord-007264-r1w9a6gc 57 1 Experiments experiment NNS cord-007264-r1w9a6gc 57 2 347 347 CD cord-007264-r1w9a6gc 57 3 were be VBD cord-007264-r1w9a6gc 57 4 done do VBN cord-007264-r1w9a6gc 57 5 in in IN cord-007264-r1w9a6gc 57 6 25-cm 25-cm CD cord-007264-r1w9a6gc 57 7 2 2 CD cord-007264-r1w9a6gc 57 8 cell cell NN cord-007264-r1w9a6gc 57 9 - - HYPH cord-007264-r1w9a6gc 57 10 culture culture NN cord-007264-r1w9a6gc 57 11 flasks flask NNS cord-007264-r1w9a6gc 57 12 . . . cord-007264-r1w9a6gc 58 1 A a DT cord-007264-r1w9a6gc 58 2 2-mL 2-ml CD cord-007264-r1w9a6gc 58 3 aliquot aliquot NN cord-007264-r1w9a6gc 58 4 of of IN cord-007264-r1w9a6gc 58 5 medium medium JJ cord-007264-r1w9a6gc 58 6 supernatant supernatant NN cord-007264-r1w9a6gc 58 7 was be VBD cord-007264-r1w9a6gc 58 8 taken take VBN cord-007264-r1w9a6gc 58 9 every every DT cord-007264-r1w9a6gc 58 10 24 24 CD cord-007264-r1w9a6gc 58 11 h h NN cord-007264-r1w9a6gc 58 12 and and CC cord-007264-r1w9a6gc 58 13 replaced replace VBN cord-007264-r1w9a6gc 58 14 with with IN cord-007264-r1w9a6gc 58 15 fresh fresh JJ cord-007264-r1w9a6gc 58 16 serum serum NN cord-007264-r1w9a6gc 58 17 - - HYPH cord-007264-r1w9a6gc 58 18 free free JJ cord-007264-r1w9a6gc 58 19 EMEM emem NN cord-007264-r1w9a6gc 58 20 . . . cord-007264-r1w9a6gc 59 1 One one CD cord-007264-r1w9a6gc 59 2 milliliter milliliter NN cord-007264-r1w9a6gc 59 3 of of IN cord-007264-r1w9a6gc 59 4 each each DT cord-007264-r1w9a6gc 59 5 aliquot aliquot NN cord-007264-r1w9a6gc 59 6 collected collect VBN cord-007264-r1w9a6gc 59 7 was be VBD cord-007264-r1w9a6gc 59 8 assayed assay VBN cord-007264-r1w9a6gc 59 9 for for IN cord-007264-r1w9a6gc 59 10 chemotactic chemotactic JJ cord-007264-r1w9a6gc 59 11 activity activity NN cord-007264-r1w9a6gc 59 12 , , , cord-007264-r1w9a6gc 59 13 and and CC cord-007264-r1w9a6gc 59 14 the the DT cord-007264-r1w9a6gc 59 15 remaining remain VBG cord-007264-r1w9a6gc 59 16 portion portion NN cord-007264-r1w9a6gc 59 17 was be VBD cord-007264-r1w9a6gc 59 18 stored store VBN cord-007264-r1w9a6gc 59 19 at at IN cord-007264-r1w9a6gc 59 20 -70 -70 NN cord-007264-r1w9a6gc 59 21 C c NN cord-007264-r1w9a6gc 59 22 until until IN cord-007264-r1w9a6gc 59 23 the the DT cord-007264-r1w9a6gc 59 24 titer titer NN cord-007264-r1w9a6gc 59 25 of of IN cord-007264-r1w9a6gc 59 26 virus virus NN cord-007264-r1w9a6gc 59 27 was be VBD cord-007264-r1w9a6gc 59 28 determined determine VBN cord-007264-r1w9a6gc 59 29 . . . cord-007264-r1w9a6gc 60 1 Determining determine VBG cord-007264-r1w9a6gc 60 2 the the DT cord-007264-r1w9a6gc 60 3 effect effect NN cord-007264-r1w9a6gc 60 4 ofcelldisruption ofcelldisruption NN cord-007264-r1w9a6gc 60 5 . . . cord-007264-r1w9a6gc 61 1 Medium medium NN cord-007264-r1w9a6gc 61 2 from from IN cord-007264-r1w9a6gc 61 3 uninfected uninfected JJ cord-007264-r1w9a6gc 61 4 cells cell NNS cord-007264-r1w9a6gc 61 5 , , , cord-007264-r1w9a6gc 61 6 which which WDT cord-007264-r1w9a6gc 61 7 were be VBD cord-007264-r1w9a6gc 61 8 disrupted disrupt VBN cord-007264-r1w9a6gc 61 9 ultrasonically ultrasonically RB cord-007264-r1w9a6gc 61 10 or or CC cord-007264-r1w9a6gc 61 11 by by IN cord-007264-r1w9a6gc 61 12 multiple multiple JJ cord-007264-r1w9a6gc 61 13 freeze freeze NN cord-007264-r1w9a6gc 61 14 - - HYPH cord-007264-r1w9a6gc 61 15 thaw thaw VB cord-007264-r1w9a6gc 61 16 cycles cycle NNS cord-007264-r1w9a6gc 61 17 , , , cord-007264-r1w9a6gc 61 18 was be VBD cord-007264-r1w9a6gc 61 19 assayed assay VBN cord-007264-r1w9a6gc 61 20 to to TO cord-007264-r1w9a6gc 61 21 determine determine VB cord-007264-r1w9a6gc 61 22 if if IN cord-007264-r1w9a6gc 61 23 the the DT cord-007264-r1w9a6gc 61 24 chemoattractant chemoattractant NN cord-007264-r1w9a6gc 61 25 was be VBD cord-007264-r1w9a6gc 61 26 a a DT cord-007264-r1w9a6gc 61 27 substance substance NN cord-007264-r1w9a6gc 61 28 preformed preform VBN cord-007264-r1w9a6gc 61 29 within within IN cord-007264-r1w9a6gc 61 30 the the DT cord-007264-r1w9a6gc 61 31 cell cell NN cord-007264-r1w9a6gc 61 32 . . . cord-007264-r1w9a6gc 62 1 Cell cell NN cord-007264-r1w9a6gc 62 2 monolayers monolayer NNS cord-007264-r1w9a6gc 62 3 maintained maintain VBD cord-007264-r1w9a6gc 62 4 in in IN cord-007264-r1w9a6gc 62 5 serum serum NN cord-007264-r1w9a6gc 62 6 - - HYPH cord-007264-r1w9a6gc 62 7 free free JJ cord-007264-r1w9a6gc 62 8 EMEM emem NN cord-007264-r1w9a6gc 62 9 were be VBD cord-007264-r1w9a6gc 62 10 frozen freeze VBN cord-007264-r1w9a6gc 62 11 at at IN cord-007264-r1w9a6gc 62 12 -70 -70 NN cord-007264-r1w9a6gc 62 13 C c NN cord-007264-r1w9a6gc 62 14 and and CC cord-007264-r1w9a6gc 62 15 thawed thaw VBN cord-007264-r1w9a6gc 62 16 at at IN cord-007264-r1w9a6gc 62 17 37 37 CD cord-007264-r1w9a6gc 62 18 C c NN cord-007264-r1w9a6gc 62 19 three three CD cord-007264-r1w9a6gc 62 20 times time NNS cord-007264-r1w9a6gc 62 21 ; ; : cord-007264-r1w9a6gc 62 22 the the DT cord-007264-r1w9a6gc 62 23 medium medium NN cord-007264-r1w9a6gc 62 24 was be VBD cord-007264-r1w9a6gc 62 25 then then RB cord-007264-r1w9a6gc 62 26 collected collect VBN cord-007264-r1w9a6gc 62 27 , , , cord-007264-r1w9a6gc 62 28 centrifuged centrifuge VBN cord-007264-r1w9a6gc 62 29 to to TO cord-007264-r1w9a6gc 62 30 remove remove VB cord-007264-r1w9a6gc 62 31 debris debris NN cord-007264-r1w9a6gc 62 32 , , , cord-007264-r1w9a6gc 62 33 and and CC cord-007264-r1w9a6gc 62 34 assayed assay VBN cord-007264-r1w9a6gc 62 35 for for IN cord-007264-r1w9a6gc 62 36 chemoattractant chemoattractant NN cord-007264-r1w9a6gc 62 37 activity activity NN cord-007264-r1w9a6gc 62 38 . . . cord-007264-r1w9a6gc 63 1 Sonication sonication NN cord-007264-r1w9a6gc 63 2 experiments experiment NNS cord-007264-r1w9a6gc 63 3 weredone weredone VBN cord-007264-r1w9a6gc 63 4 by by IN cord-007264-r1w9a6gc 63 5 scraping scrape VBG cord-007264-r1w9a6gc 63 6 the the DT cord-007264-r1w9a6gc 63 7 MRC-5 MRC-5 NNP cord-007264-r1w9a6gc 63 8 cell cell NN cord-007264-r1w9a6gc 63 9 monolayer monolayer NN cord-007264-r1w9a6gc 63 10 into into IN cord-007264-r1w9a6gc 63 11 serum serum NN cord-007264-r1w9a6gc 63 12 - - HYPH cord-007264-r1w9a6gc 63 13 free free JJ cord-007264-r1w9a6gc 63 14 medium medium NN cord-007264-r1w9a6gc 63 15 and and CC cord-007264-r1w9a6gc 63 16 sonicating sonicate VBG cord-007264-r1w9a6gc 63 17 the the DT cord-007264-r1w9a6gc 63 18 specimen specimen NN cord-007264-r1w9a6gc 63 19 with with IN cord-007264-r1w9a6gc 63 20 a a DT cord-007264-r1w9a6gc 63 21 microtip microtip NN cord-007264-r1w9a6gc 63 22 sonicator sonicator NN cord-007264-r1w9a6gc 63 23 ( ( -LRB- cord-007264-r1w9a6gc 63 24 Heat Heat NNP cord-007264-r1w9a6gc 63 25 Systems Systems NNPS cord-007264-r1w9a6gc 63 26 - - : cord-007264-r1w9a6gc 63 27 Ultrasonics Ultrasonics NNP cord-007264-r1w9a6gc 63 28 , , , cord-007264-r1w9a6gc 63 29 Plainview Plainview NNP cord-007264-r1w9a6gc 63 30 , , , cord-007264-r1w9a6gc 63 31 NY NY NNP cord-007264-r1w9a6gc 63 32 ) ) -RRB- cord-007264-r1w9a6gc 63 33 . . . cord-007264-r1w9a6gc 64 1 The the DT cord-007264-r1w9a6gc 64 2 specimen specimen NN cord-007264-r1w9a6gc 64 3 was be VBD cord-007264-r1w9a6gc 64 4 centrifuged centrifuge VBN cord-007264-r1w9a6gc 64 5 to to TO cord-007264-r1w9a6gc 64 6 remove remove VB cord-007264-r1w9a6gc 64 7 debris debris NN cord-007264-r1w9a6gc 64 8 and and CC cord-007264-r1w9a6gc 64 9 assayed assay VBN cord-007264-r1w9a6gc 64 10 for for IN cord-007264-r1w9a6gc 64 11 chemoattractant chemoattractant NN cord-007264-r1w9a6gc 64 12 activity activity NN cord-007264-r1w9a6gc 64 13 . . . cord-007264-r1w9a6gc 65 1 Virus virus NN cord-007264-r1w9a6gc 65 2 - - HYPH cord-007264-r1w9a6gc 65 3 infected infect VBN cord-007264-r1w9a6gc 65 4 cell cell NN cord-007264-r1w9a6gc 65 5 cultures culture NNS cord-007264-r1w9a6gc 65 6 handled handle VBN cord-007264-r1w9a6gc 65 7 in in IN cord-007264-r1w9a6gc 65 8 an an DT cord-007264-r1w9a6gc 65 9 identical identical JJ cord-007264-r1w9a6gc 65 10 fashion fashion NN cord-007264-r1w9a6gc 65 11 were be VBD cord-007264-r1w9a6gc 65 12 assayed assay VBN cord-007264-r1w9a6gc 65 13 to to TO cord-007264-r1w9a6gc 65 14 control control VB cord-007264-r1w9a6gc 65 15 for for IN cord-007264-r1w9a6gc 65 16 destruction destruction NN cord-007264-r1w9a6gc 65 17 of of IN cord-007264-r1w9a6gc 65 18 the the DT cord-007264-r1w9a6gc 65 19 chemoattractant chemoattractant NN cord-007264-r1w9a6gc 65 20 by by IN cord-007264-r1w9a6gc 65 21 freeze freeze NN cord-007264-r1w9a6gc 65 22 - - HYPH cord-007264-r1w9a6gc 65 23 thawing thawing NN cord-007264-r1w9a6gc 65 24 or or CC cord-007264-r1w9a6gc 65 25 sonication sonication NN cord-007264-r1w9a6gc 65 26 . . . cord-007264-r1w9a6gc 66 1 Associating associate VBG cord-007264-r1w9a6gc 66 2 chemoattractant chemoattractant NN cord-007264-r1w9a6gc 66 3 activity activity NN cord-007264-r1w9a6gc 66 4 with with IN cord-007264-r1w9a6gc 66 5 infectious infectious JJ cord-007264-r1w9a6gc 66 6 virus virus NN cord-007264-r1w9a6gc 66 7 . . . cord-007264-r1w9a6gc 67 1 Supernatant supernatant JJ cord-007264-r1w9a6gc 67 2 from from IN cord-007264-r1w9a6gc 67 3 rhinovirus rhinovirus NN cord-007264-r1w9a6gc 67 4 - - HYPH cord-007264-r1w9a6gc 67 5 infected infect VBN cord-007264-r1w9a6gc 67 6 MRC-5 MRC-5 NNP cord-007264-r1w9a6gc 67 7 cells cell NNS cord-007264-r1w9a6gc 67 8 was be VBD cord-007264-r1w9a6gc 67 9 centrifuged centrifuge VBN cord-007264-r1w9a6gc 67 10 at at IN cord-007264-r1w9a6gc 67 11 100 100 CD cord-007264-r1w9a6gc 67 12 000 000 CD cord-007264-r1w9a6gc 67 13 g g NN cord-007264-r1w9a6gc 67 14 ( ( -LRB- cord-007264-r1w9a6gc 67 15 Beckman Beckman NNP cord-007264-r1w9a6gc 67 16 L5 L5 NNP cord-007264-r1w9a6gc 67 17 - - HYPH cord-007264-r1w9a6gc 67 18 65 65 CD cord-007264-r1w9a6gc 67 19 ultracentrifuge ultracentrifuge NN cord-007264-r1w9a6gc 67 20 , , , cord-007264-r1w9a6gc 67 21 SW65 SW65 NNP cord-007264-r1w9a6gc 67 22 rotor rotor NN cord-007264-r1w9a6gc 67 23 ; ; : cord-007264-r1w9a6gc 67 24 Beckman Beckman NNP cord-007264-r1w9a6gc 67 25 ) ) -RRB- cord-007264-r1w9a6gc 67 26 for for IN cord-007264-r1w9a6gc 67 27 24 24 CD cord-007264-r1w9a6gc 67 28 h. h. NN cord-007264-r1w9a6gc 68 1 The the DT cord-007264-r1w9a6gc 68 2 pellet pellet NN cord-007264-r1w9a6gc 68 3 was be VBD cord-007264-r1w9a6gc 68 4 resuspended resuspend VBN cord-007264-r1w9a6gc 68 5 in in IN cord-007264-r1w9a6gc 68 6 fresh fresh JJ cord-007264-r1w9a6gc 68 7 serum serum NN cord-007264-r1w9a6gc 68 8 - - HYPH cord-007264-r1w9a6gc 68 9 free free JJ cord-007264-r1w9a6gc 68 10 medium medium NN cord-007264-r1w9a6gc 68 11 to to IN cord-007264-r1w9a6gc 68 12 the the DT cord-007264-r1w9a6gc 68 13 original original JJ cord-007264-r1w9a6gc 68 14 volume volume NN cord-007264-r1w9a6gc 68 15 ; ; : cord-007264-r1w9a6gc 68 16 both both CC cord-007264-r1w9a6gc 68 17 the the DT cord-007264-r1w9a6gc 68 18 resuspended resuspended JJ cord-007264-r1w9a6gc 68 19 sediment sediment NN cord-007264-r1w9a6gc 68 20 and and CC cord-007264-r1w9a6gc 68 21 the the DT cord-007264-r1w9a6gc 68 22 original original JJ cord-007264-r1w9a6gc 68 23 supernatant supernatant NN cord-007264-r1w9a6gc 68 24 were be VBD cord-007264-r1w9a6gc 68 25 assayed assay VBN cord-007264-r1w9a6gc 68 26 for for IN cord-007264-r1w9a6gc 68 27 infectious infectious JJ cord-007264-r1w9a6gc 68 28 virus virus NN cord-007264-r1w9a6gc 68 29 and and CC cord-007264-r1w9a6gc 68 30 for for IN cord-007264-r1w9a6gc 68 31 chemoattractant chemoattractant NN cord-007264-r1w9a6gc 68 32 activity activity NN cord-007264-r1w9a6gc 68 33 . . . cord-007264-r1w9a6gc 69 1 Attachment attachment NN cord-007264-r1w9a6gc 69 2 of of IN cord-007264-r1w9a6gc 69 3 virus virus NN cord-007264-r1w9a6gc 69 4 . . . cord-007264-r1w9a6gc 70 1 To to TO cord-007264-r1w9a6gc 70 2 determine determine VB cord-007264-r1w9a6gc 70 3 whether whether IN cord-007264-r1w9a6gc 70 4 viral viral JJ cord-007264-r1w9a6gc 70 5 infection infection NN cord-007264-r1w9a6gc 70 6 of of IN cord-007264-r1w9a6gc 70 7 the the DT cord-007264-r1w9a6gc 70 8 cell cell NN cord-007264-r1w9a6gc 70 9 monolayer monolayer NN cord-007264-r1w9a6gc 70 10 was be VBD cord-007264-r1w9a6gc 70 11 necessary necessary JJ cord-007264-r1w9a6gc 70 12 for for IN cord-007264-r1w9a6gc 70 13 elaboration elaboration NN cord-007264-r1w9a6gc 70 14 of of IN cord-007264-r1w9a6gc 70 15 the the DT cord-007264-r1w9a6gc 70 16 chemoattractant chemoattractant NN cord-007264-r1w9a6gc 70 17 , , , cord-007264-r1w9a6gc 70 18 we -PRON- PRP cord-007264-r1w9a6gc 70 19 inactivated inactivate VBD cord-007264-r1w9a6gc 70 20 R39 R39 NNP cord-007264-r1w9a6gc 70 21 by by IN cord-007264-r1w9a6gc 70 22 exposure exposure NN cord-007264-r1w9a6gc 70 23 to to IN cord-007264-r1w9a6gc 70 24 UV uv NN cord-007264-r1w9a6gc 70 25 light light NN cord-007264-r1w9a6gc 70 26 for for IN cord-007264-r1w9a6gc 70 27 30 30 CD cord-007264-r1w9a6gc 70 28 min min NN cord-007264-r1w9a6gc 70 29 . . . cord-007264-r1w9a6gc 71 1 The the DT cord-007264-r1w9a6gc 71 2 inactivated inactivated JJ cord-007264-r1w9a6gc 71 3 virus virus NN cord-007264-r1w9a6gc 71 4 was be VBD cord-007264-r1w9a6gc 71 5 then then RB cord-007264-r1w9a6gc 71 6 inoculated inoculate VBN cord-007264-r1w9a6gc 71 7 onto onto IN cord-007264-r1w9a6gc 71 8 monolayers monolayer NNS cord-007264-r1w9a6gc 71 9 of of IN cord-007264-r1w9a6gc 71 10 MRC-5 MRC-5 NNP cord-007264-r1w9a6gc 71 11 cells cell NNS cord-007264-r1w9a6gc 71 12 and and CC cord-007264-r1w9a6gc 71 13 incubated incubate VBN cord-007264-r1w9a6gc 71 14 at at IN cord-007264-r1w9a6gc 71 15 33 33 CD cord-007264-r1w9a6gc 71 16 C c NN cord-007264-r1w9a6gc 71 17 for for IN cord-007264-r1w9a6gc 71 18 48 48 CD cord-007264-r1w9a6gc 71 19 h. h. NNP cord-007264-r1w9a6gc 71 20 Control Control NNP cord-007264-r1w9a6gc 71 21 monolayers monolayer NNS cord-007264-r1w9a6gc 71 22 that that WDT cord-007264-r1w9a6gc 71 23 had have VBD cord-007264-r1w9a6gc 71 24 been be VBN cord-007264-r1w9a6gc 71 25 inoculated inoculate VBN cord-007264-r1w9a6gc 71 26 with with IN cord-007264-r1w9a6gc 71 27 infectious infectious JJ cord-007264-r1w9a6gc 71 28 virus virus NN cord-007264-r1w9a6gc 71 29 or or CC cord-007264-r1w9a6gc 71 30 with with IN cord-007264-r1w9a6gc 71 31 uninfected uninfected JJ cord-007264-r1w9a6gc 71 32 cell cell NN cord-007264-r1w9a6gc 71 33 - - HYPH cord-007264-r1w9a6gc 71 34 culture culture NN cord-007264-r1w9a6gc 71 35 medium medium NN cord-007264-r1w9a6gc 71 36 were be VBD cord-007264-r1w9a6gc 71 37 handled handle VBN cord-007264-r1w9a6gc 71 38 identically identically RB cord-007264-r1w9a6gc 71 39 . . . cord-007264-r1w9a6gc 72 1 After after IN cord-007264-r1w9a6gc 72 2 48 48 CD cord-007264-r1w9a6gc 72 3 h h NN cord-007264-r1w9a6gc 72 4 , , , cord-007264-r1w9a6gc 72 5 medium medium NN cord-007264-r1w9a6gc 72 6 from from IN cord-007264-r1w9a6gc 72 7 the the DT cord-007264-r1w9a6gc 72 8 experimental experimental JJ cord-007264-r1w9a6gc 72 9 and and CC cord-007264-r1w9a6gc 72 10 the the DT cord-007264-r1w9a6gc 72 11 control control NN cord-007264-r1w9a6gc 72 12 monolayers monolayer NNS cord-007264-r1w9a6gc 72 13 was be VBD cord-007264-r1w9a6gc 72 14 assayed assay VBN cord-007264-r1w9a6gc 72 15 for for IN cord-007264-r1w9a6gc 72 16 chemotactic chemotactic JJ cord-007264-r1w9a6gc 72 17 activity activity NN cord-007264-r1w9a6gc 72 18 . . . cord-007264-r1w9a6gc 73 1 Chemoattractant chemoattractant JJ cord-007264-r1w9a6gc 73 2 activity activity NN cord-007264-r1w9a6gc 73 3 of of IN cord-007264-r1w9a6gc 73 4 other other JJ cord-007264-r1w9a6gc 73 5 viruses virus NNS cord-007264-r1w9a6gc 73 6 . . . cord-007264-r1w9a6gc 74 1 Respiratory respiratory JJ cord-007264-r1w9a6gc 74 2 syncytial syncytial JJ cord-007264-r1w9a6gc 74 3 virus virus NN cord-007264-r1w9a6gc 74 4 ( ( -LRB- cord-007264-r1w9a6gc 74 5 RSV RSV NNP cord-007264-r1w9a6gc 74 6 ) ) -RRB- cord-007264-r1w9a6gc 74 7 and and CC cord-007264-r1w9a6gc 74 8 coronavirus coronavirus NN cord-007264-r1w9a6gc 74 9 229E 229e CD cord-007264-r1w9a6gc 74 10 were be VBD cord-007264-r1w9a6gc 74 11 inoculated inoculate VBN cord-007264-r1w9a6gc 74 12 into into IN cord-007264-r1w9a6gc 74 13 MRC-5 MRC-5 NNP cord-007264-r1w9a6gc 74 14 cell cell NN cord-007264-r1w9a6gc 74 15 cultures culture NNS cord-007264-r1w9a6gc 74 16 maintained maintain VBN cord-007264-r1w9a6gc 74 17 in in IN cord-007264-r1w9a6gc 74 18 serum serum NN cord-007264-r1w9a6gc 74 19 - - HYPH cord-007264-r1w9a6gc 74 20 free free JJ cord-007264-r1w9a6gc 74 21 medium medium NN cord-007264-r1w9a6gc 74 22 as as IN cord-007264-r1w9a6gc 74 23 described describe VBN cord-007264-r1w9a6gc 74 24 for for IN cord-007264-r1w9a6gc 74 25 R39 R39 NNP cord-007264-r1w9a6gc 74 26 . . . cord-007264-r1w9a6gc 75 1 RSV RSV NNP cord-007264-r1w9a6gc 75 2 was be VBD cord-007264-r1w9a6gc 75 3 also also RB cord-007264-r1w9a6gc 75 4 inoculated inoculate VBN cord-007264-r1w9a6gc 75 5 into into IN cord-007264-r1w9a6gc 75 6 HeLa HeLa NNP cord-007264-r1w9a6gc 75 7 cell cell NN cord-007264-r1w9a6gc 75 8 cultures culture NNS cord-007264-r1w9a6gc 75 9 maintained maintain VBN cord-007264-r1w9a6gc 75 10 in in IN cord-007264-r1w9a6gc 75 11 serum serum NN cord-007264-r1w9a6gc 75 12 - - HYPH cord-007264-r1w9a6gc 75 13 free free JJ cord-007264-r1w9a6gc 75 14 medium medium NN cord-007264-r1w9a6gc 75 15 . . . cord-007264-r1w9a6gc 76 1 After after IN cord-007264-r1w9a6gc 76 2 incubation incubation NN cord-007264-r1w9a6gc 76 3 at at IN cord-007264-r1w9a6gc 76 4 33 33 CD cord-007264-r1w9a6gc 76 5 C c NN cord-007264-r1w9a6gc 76 6 for for IN cord-007264-r1w9a6gc 76 7 48 48 CD cord-007264-r1w9a6gc 76 8 h h NN cord-007264-r1w9a6gc 76 9 , , , cord-007264-r1w9a6gc 76 10 media medium NNS cord-007264-r1w9a6gc 76 11 from from IN cord-007264-r1w9a6gc 76 12 both both CC cord-007264-r1w9a6gc 76 13 infected infect VBN cord-007264-r1w9a6gc 76 14 and and CC cord-007264-r1w9a6gc 76 15 control control NN cord-007264-r1w9a6gc 76 16 monolayers monolayer NNS cord-007264-r1w9a6gc 76 17 was be VBD cord-007264-r1w9a6gc 76 18 assayed assay VBN cord-007264-r1w9a6gc 76 19 for for IN cord-007264-r1w9a6gc 76 20 chemoattractant chemoattractant NN cord-007264-r1w9a6gc 76 21 activity activity NN cord-007264-r1w9a6gc 76 22 . . . cord-007264-r1w9a6gc 77 1 medium medium NN cord-007264-r1w9a6gc 77 2 from from IN cord-007264-r1w9a6gc 77 3 infected infected JJ cord-007264-r1w9a6gc 77 4 cells cell NNS cord-007264-r1w9a6gc 77 5 ) ) -RRB- cord-007264-r1w9a6gc 77 6 . . . cord-007264-r1w9a6gc 78 1 Treatment treatment NN cord-007264-r1w9a6gc 78 2 by by IN cord-007264-r1w9a6gc 78 3 sonication sonication NN cord-007264-r1w9a6gc 78 4 or or CC cord-007264-r1w9a6gc 78 5 multiple multiple JJ cord-007264-r1w9a6gc 78 6 freeze freeze NN cord-007264-r1w9a6gc 78 7 - - HYPH cord-007264-r1w9a6gc 78 8 thaw thaw VB cord-007264-r1w9a6gc 78 9 cyclesof cyclesof NNS cord-007264-r1w9a6gc 78 10 medium medium NN cord-007264-r1w9a6gc 78 11 from from IN cord-007264-r1w9a6gc 78 12 rhinovirus rhinovirus NN cord-007264-r1w9a6gc 78 13 - - HYPH cord-007264-r1w9a6gc 78 14 infected infect VBN cord-007264-r1w9a6gc 78 15 cells cell NNS cord-007264-r1w9a6gc 78 16 did do VBD cord-007264-r1w9a6gc 78 17 not not RB cord-007264-r1w9a6gc 78 18 alter alter VB cord-007264-r1w9a6gc 78 19 its -PRON- PRP$ cord-007264-r1w9a6gc 78 20 chemoattractant chemoattractant NN cord-007264-r1w9a6gc 78 21 effect effect NN cord-007264-r1w9a6gc 78 22 . . . cord-007264-r1w9a6gc 79 1 After after IN cord-007264-r1w9a6gc 79 2 ultracentrifugation ultracentrifugation NN cord-007264-r1w9a6gc 79 3 of of IN cord-007264-r1w9a6gc 79 4 the the DT cord-007264-r1w9a6gc 79 5 medium medium NN cord-007264-r1w9a6gc 79 6 from from IN cord-007264-r1w9a6gc 79 7 infected infected JJ cord-007264-r1w9a6gc 79 8 MRC-5 MRC-5 NNP cord-007264-r1w9a6gc 79 9 cells cell NNS cord-007264-r1w9a6gc 79 10 , , , cord-007264-r1w9a6gc 79 11 the the DT cord-007264-r1w9a6gc 79 12 titer titer NN cord-007264-r1w9a6gc 79 13 of of IN cord-007264-r1w9a6gc 79 14 virus virus NN cord-007264-r1w9a6gc 79 15 in in IN cord-007264-r1w9a6gc 79 16 the the DT cord-007264-r1w9a6gc 79 17 supernatant supernatant NN cord-007264-r1w9a6gc 79 18 was be VBD cord-007264-r1w9a6gc 79 19 3.2 3.2 CD cord-007264-r1w9a6gc 79 20 x x SYM cord-007264-r1w9a6gc 79 21 10 10 CD cord-007264-r1w9a6gc 79 22 2 2 CD cord-007264-r1w9a6gc 79 23 TCIDsolmL tcidsolml CD cord-007264-r1w9a6gc 79 24 compared compare VBN cord-007264-r1w9a6gc 79 25 with with IN cord-007264-r1w9a6gc 79 26 1.6 1.6 CD cord-007264-r1w9a6gc 79 27 x x SYM cord-007264-r1w9a6gc 79 28 10 10 CD cord-007264-r1w9a6gc 79 29 4 4 CD cord-007264-r1w9a6gc 79 30 TCIDso TCIDso NNP cord-007264-r1w9a6gc 79 31 / / SYM cord-007264-r1w9a6gc 79 32 mL ml NN cord-007264-r1w9a6gc 79 33 in in IN cord-007264-r1w9a6gc 79 34 the the DT cord-007264-r1w9a6gc 79 35 sediment sediment NN cord-007264-r1w9a6gc 79 36 . . . cord-007264-r1w9a6gc 80 1 In in IN cord-007264-r1w9a6gc 80 2 contrast contrast NN cord-007264-r1w9a6gc 80 3 , , , cord-007264-r1w9a6gc 80 4 the the DT cord-007264-r1w9a6gc 80 5 supernatant supernatant NN cord-007264-r1w9a6gc 80 6 attracted attract VBD cord-007264-r1w9a6gc 80 7 102PMNLs 102pmnls CD cord-007264-r1w9a6gc 80 8 / / SYM cord-007264-r1w9a6gc 80 9 lO lO NNP cord-007264-r1w9a6gc 80 10 hpf hpf NN cord-007264-r1w9a6gc 80 11 , , , cord-007264-r1w9a6gc 80 12 compared compare VBN cord-007264-r1w9a6gc 80 13 with with IN cord-007264-r1w9a6gc 80 14 16 16 CD cord-007264-r1w9a6gc 80 15 PMNLs/ PMNLs/ NNP cord-007264-r1w9a6gc 81 1 lO lO NNP cord-007264-r1w9a6gc 81 2 hpf hpf NN cord-007264-r1w9a6gc 81 3 attracted attract VBN cord-007264-r1w9a6gc 81 4 by by IN cord-007264-r1w9a6gc 81 5 the the DT cord-007264-r1w9a6gc 81 6 sediment sediment NN cord-007264-r1w9a6gc 81 7 . . . cord-007264-r1w9a6gc 82 1 These these DT cord-007264-r1w9a6gc 82 2 results result NNS cord-007264-r1w9a6gc 82 3 suggest suggest VBP cord-007264-r1w9a6gc 82 4 that that IN cord-007264-r1w9a6gc 82 5 the the DT cord-007264-r1w9a6gc 82 6 chemoattractant chemoattractant NN cord-007264-r1w9a6gc 82 7 activity activity NN cord-007264-r1w9a6gc 82 8 is be VBZ cord-007264-r1w9a6gc 82 9 not not RB cord-007264-r1w9a6gc 82 10 directly directly RB cord-007264-r1w9a6gc 82 11 associated associate VBN cord-007264-r1w9a6gc 82 12 with with IN cord-007264-r1w9a6gc 82 13 infectious infectious JJ cord-007264-r1w9a6gc 82 14 viral viral JJ cord-007264-r1w9a6gc 82 15 particles particle NNS cord-007264-r1w9a6gc 82 16 . . . cord-007264-r1w9a6gc 83 1 Medium medium NN cord-007264-r1w9a6gc 83 2 collected collect VBN cord-007264-r1w9a6gc 83 3 from from IN cord-007264-r1w9a6gc 83 4 MRC-5 MRC-5 NNP cord-007264-r1w9a6gc 84 1 cellsthat cellsthat NNP cord-007264-r1w9a6gc 84 2 had have VBD cord-007264-r1w9a6gc 84 3 been be VBN cord-007264-r1w9a6gc 84 4 ... ... . cord-007264-r1w9a6gc 85 1 Comparisons comparison NNS cord-007264-r1w9a6gc 85 2 in in IN cord-007264-r1w9a6gc 85 3 all all DT cord-007264-r1w9a6gc 85 4 other other JJ cord-007264-r1w9a6gc 85 5 experiments experiment NNS cord-007264-r1w9a6gc 85 6 were be VBD cord-007264-r1w9a6gc 85 7 made make VBN cord-007264-r1w9a6gc 85 8 by by IN cord-007264-r1w9a6gc 85 9 using use VBG cord-007264-r1w9a6gc 85 10 a a DT cord-007264-r1w9a6gc 85 11 two two CD cord-007264-r1w9a6gc 85 12 - - HYPH cord-007264-r1w9a6gc 85 13 sided sided JJ cord-007264-r1w9a6gc 85 14 Mann Mann NNP cord-007264-r1w9a6gc 85 15 - - HYPH cord-007264-r1w9a6gc 85 16 Whitney Whitney NNP cord-007264-r1w9a6gc 85 17 U U NNP cord-007264-r1w9a6gc 85 18 test test NN cord-007264-r1w9a6gc 85 19 . . . cord-007264-r1w9a6gc 86 1 The the DT cord-007264-r1w9a6gc 86 2 mean mean NN cord-007264-r1w9a6gc 86 3 and and CC cord-007264-r1w9a6gc 86 4 SE SE NNP cord-007264-r1w9a6gc 86 5 were be VBD cord-007264-r1w9a6gc 86 6 calculated calculate VBN cord-007264-r1w9a6gc 86 7 for for IN cord-007264-r1w9a6gc 86 8 each each DT cord-007264-r1w9a6gc 86 9 of of IN cord-007264-r1w9a6gc 86 10 the the DT cord-007264-r1w9a6gc 86 11 observations observation NNS cord-007264-r1w9a6gc 86 12 . . . cord-007264-r1w9a6gc 87 1 Four four CD cord-007264-r1w9a6gc 87 2 measurements measurement NNS cord-007264-r1w9a6gc 87 3 were be VBD cord-007264-r1w9a6gc 87 4 made make VBN cord-007264-r1w9a6gc 87 5 on on IN cord-007264-r1w9a6gc 87 6 each each DT cord-007264-r1w9a6gc 87 7 specimen specimen NN cord-007264-r1w9a6gc 87 8 ; ; : cord-007264-r1w9a6gc 87 9 specimens specimen NNS cord-007264-r1w9a6gc 87 10 obtained obtain VBN cord-007264-r1w9a6gc 87 11 from from IN cord-007264-r1w9a6gc 87 12 different different JJ cord-007264-r1w9a6gc 87 13 monolayers monolayer NNS cord-007264-r1w9a6gc 87 14 were be VBD cord-007264-r1w9a6gc 87 15 considered consider VBN cord-007264-r1w9a6gc 87 16 to to TO cord-007264-r1w9a6gc 87 17 be be VB cord-007264-r1w9a6gc 87 18 separate separate JJ cord-007264-r1w9a6gc 87 19 experiments experiment NNS cord-007264-r1w9a6gc 87 20 . . . cord-007264-r1w9a6gc 88 1 Human human JJ cord-007264-r1w9a6gc 88 2 embryonic embryonic JJ cord-007264-r1w9a6gc 88 3 lung lung NN cord-007264-r1w9a6gc 88 4 fibroblast fibroblast NN cord-007264-r1w9a6gc 88 5 cellsinfected cellsinfecte VBN cord-007264-r1w9a6gc 88 6 with with IN cord-007264-r1w9a6gc 88 7 rhinovirus rhinovirus NN cord-007264-r1w9a6gc 88 8 produced produce VBD cord-007264-r1w9a6gc 88 9 a a DT cord-007264-r1w9a6gc 88 10 chemoattractant chemoattractant NN cord-007264-r1w9a6gc 88 11 for for IN cord-007264-r1w9a6gc 88 12 PMNLs pmnl NNS cord-007264-r1w9a6gc 88 13 . . . cord-007264-r1w9a6gc 89 1 Media medium NNS cord-007264-r1w9a6gc 89 2 from from IN cord-007264-r1w9a6gc 89 3 R39-infected r39-infected JJ cord-007264-r1w9a6gc 89 4 and and CC cord-007264-r1w9a6gc 89 5 uninfected uninfected JJ cord-007264-r1w9a6gc 89 6 cells cell NNS cord-007264-r1w9a6gc 89 7 attracted attract VBD cord-007264-r1w9a6gc 89 8 87 87 CD cord-007264-r1w9a6gc 89 9 ± ± CD cord-007264-r1w9a6gc 89 10 6 6 CD cord-007264-r1w9a6gc 90 1 ( ( -LRB- cord-007264-r1w9a6gc 90 2 mean mean VB cord-007264-r1w9a6gc 90 3 ± ± NNP cord-007264-r1w9a6gc 90 4 SE SE NNP cord-007264-r1w9a6gc 90 5 ) ) -RRB- cord-007264-r1w9a6gc 90 6 and and CC cord-007264-r1w9a6gc 90 7 38 38 CD cord-007264-r1w9a6gc 90 8 ± ± NNP cord-007264-r1w9a6gc 90 9 6 6 CD cord-007264-r1w9a6gc 90 10 PMNLs/ PMNLs/ NNP cord-007264-r1w9a6gc 90 11 10 10 CD cord-007264-r1w9a6gc 90 12 hpf hpf NN cord-007264-r1w9a6gc 90 13 , , , cord-007264-r1w9a6gc 90 14 respectively respectively RB cord-007264-r1w9a6gc 90 15 ( ( -LRB- cord-007264-r1w9a6gc 90 16 P p NN cord-007264-r1w9a6gc 90 17 = = SYM cord-007264-r1w9a6gc 90 18 .0001 .0001 NN cord-007264-r1w9a6gc 90 19 ) ) -RRB- cord-007264-r1w9a6gc 90 20 . . . cord-007264-r1w9a6gc 91 1 The the DT cord-007264-r1w9a6gc 91 2 positive positive JJ cord-007264-r1w9a6gc 91 3 controls control NNS cord-007264-r1w9a6gc 91 4 attracted attract VBD cord-007264-r1w9a6gc 91 5 122 122 CD cord-007264-r1w9a6gc 91 6 ± ± CD cord-007264-r1w9a6gc 91 7 10 10 CD cord-007264-r1w9a6gc 91 8 PMNLs pmnl NNS cord-007264-r1w9a6gc 91 9 / / SYM cord-007264-r1w9a6gc 91 10 lO lO NNP cord-007264-r1w9a6gc 91 11 hpf hpf NNP cord-007264-r1w9a6gc 91 12 and and CC cord-007264-r1w9a6gc 91 13 the the DT cord-007264-r1w9a6gc 91 14 negative negative JJ cord-007264-r1w9a6gc 91 15 controls control NNS cord-007264-r1w9a6gc 91 16 , , , cord-007264-r1w9a6gc 91 17 8 8 CD cord-007264-r1w9a6gc 91 18 ± ± NNP cord-007264-r1w9a6gc 91 19 1 1 CD cord-007264-r1w9a6gc 91 20 PMNLs pmnl NNS cord-007264-r1w9a6gc 91 21 / / SYM cord-007264-r1w9a6gc 91 22 lO lO NNP cord-007264-r1w9a6gc 91 23 hpf hpf NN cord-007264-r1w9a6gc 91 24 . . . cord-007264-r1w9a6gc 92 1 When when WRB cord-007264-r1w9a6gc 92 2 medium medium NN cord-007264-r1w9a6gc 92 3 from from IN cord-007264-r1w9a6gc 92 4 infected infected JJ cord-007264-r1w9a6gc 92 5 cells cell NNS cord-007264-r1w9a6gc 92 6 was be VBD cord-007264-r1w9a6gc 92 7 placed place VBN cord-007264-r1w9a6gc 92 8 above above IN cord-007264-r1w9a6gc 92 9 and and CC cord-007264-r1w9a6gc 92 10 below below IN cord-007264-r1w9a6gc 92 11 the the DT cord-007264-r1w9a6gc 92 12 filter filter NN cord-007264-r1w9a6gc 92 13 to to TO cord-007264-r1w9a6gc 92 14 remove remove VB cord-007264-r1w9a6gc 92 15 the the DT cord-007264-r1w9a6gc 92 16 chemotactic chemotactic JJ cord-007264-r1w9a6gc 92 17 gradient gradient NN cord-007264-r1w9a6gc 92 18 , , , cord-007264-r1w9a6gc 92 19 the the DT cord-007264-r1w9a6gc 92 20 mean mean JJ cord-007264-r1w9a6gc 92 21 number number NN cord-007264-r1w9a6gc 92 22 of of IN cord-007264-r1w9a6gc 92 23 cellsmigrating cellsmigrate VBG cord-007264-r1w9a6gc 92 24 through through IN cord-007264-r1w9a6gc 92 25 the the DT cord-007264-r1w9a6gc 92 26 filter filter NN cord-007264-r1w9a6gc 92 27 per per IN cord-007264-r1w9a6gc 92 28 10 10 CD cord-007264-r1w9a6gc 92 29 hpf hpf NN cord-007264-r1w9a6gc 92 30 was be VBD cord-007264-r1w9a6gc 92 31 8 8 CD cord-007264-r1w9a6gc 92 32 ± ± NNP cord-007264-r1w9a6gc 92 33 1 1 CD cord-007264-r1w9a6gc 92 34 . . . cord-007264-r1w9a6gc 93 1 Incubation incubation NN cord-007264-r1w9a6gc 93 2 of of IN cord-007264-r1w9a6gc 93 3 PMNLs pmnl NNS cord-007264-r1w9a6gc 93 4 with with IN cord-007264-r1w9a6gc 93 5 the the DT cord-007264-r1w9a6gc 93 6 rhinovirus rhinovirus NN cord-007264-r1w9a6gc 93 7 - - HYPH cord-007264-r1w9a6gc 93 8 induced induce VBN cord-007264-r1w9a6gc 93 9 chemoattractant chemoattractant NN cord-007264-r1w9a6gc 93 10 did do VBD cord-007264-r1w9a6gc 93 11 not not RB cord-007264-r1w9a6gc 93 12 affect affect VB cord-007264-r1w9a6gc 93 13 migration migration NN cord-007264-r1w9a6gc 93 14 toward toward IN cord-007264-r1w9a6gc 93 15 wells well NNS cord-007264-r1w9a6gc 93 16 containing contain VBG cord-007264-r1w9a6gc 93 17 FMLP FMLP NNP cord-007264-r1w9a6gc 93 18 . . . cord-007264-r1w9a6gc 94 1 Chemoattractant chemoattractant NN cord-007264-r1w9a6gc 94 2 activity activity NN cord-007264-r1w9a6gc 94 3 similar similar JJ cord-007264-r1w9a6gc 94 4 to to IN cord-007264-r1w9a6gc 94 5 that that DT cord-007264-r1w9a6gc 94 6 induced induce VBN cord-007264-r1w9a6gc 94 7 by by IN cord-007264-r1w9a6gc 94 8 R39 R39 NNP cord-007264-r1w9a6gc 94 9 was be VBD cord-007264-r1w9a6gc 94 10 detected detect VBN cord-007264-r1w9a6gc 94 11 when when WRB cord-007264-r1w9a6gc 94 12 MRC-5 MRC-5 NNP cord-007264-r1w9a6gc 94 13 cells cell NNS cord-007264-r1w9a6gc 94 14 were be VBD cord-007264-r1w9a6gc 94 15 infected infect VBN cord-007264-r1w9a6gc 94 16 with with IN cord-007264-r1w9a6gc 94 17 rhinovirus rhinovirus NN cord-007264-r1w9a6gc 94 18 types type NNS cord-007264-r1w9a6gc 94 19 2 2 CD cord-007264-r1w9a6gc 94 20 and and CC cord-007264-r1w9a6gc 94 21 14 14 CD cord-007264-r1w9a6gc 94 22 . . . cord-007264-r1w9a6gc 95 1 Medium medium NN cord-007264-r1w9a6gc 95 2 from from IN cord-007264-r1w9a6gc 95 3 cells cell NNS cord-007264-r1w9a6gc 95 4 infected infect VBN cord-007264-r1w9a6gc 95 5 with with IN cord-007264-r1w9a6gc 95 6 rhinovirus rhinovirus NN cord-007264-r1w9a6gc 95 7 type type NN cord-007264-r1w9a6gc 95 8 2 2 CD cord-007264-r1w9a6gc 95 9 attracted attract VBD cord-007264-r1w9a6gc 95 10 73 73 CD cord-007264-r1w9a6gc 95 11 ± ± NNP cord-007264-r1w9a6gc 95 12 15 15 CD cord-007264-r1w9a6gc 95 13 PMNLs pmnl NNS cord-007264-r1w9a6gc 95 14 / / SYM cord-007264-r1w9a6gc 95 15 lO lO NNP cord-007264-r1w9a6gc 95 16 hpf hpf NN cord-007264-r1w9a6gc 95 17 , , , cord-007264-r1w9a6gc 95 18 and and CC cord-007264-r1w9a6gc 95 19 medium medium NN cord-007264-r1w9a6gc 95 20 from from IN cord-007264-r1w9a6gc 95 21 rhinovirus rhinovirus NN cord-007264-r1w9a6gc 95 22 type type NN cord-007264-r1w9a6gc 95 23 14-infected 14-infected CD cord-007264-r1w9a6gc 95 24 cells cell NNS cord-007264-r1w9a6gc 96 1 attracted attract VBD cord-007264-r1w9a6gc 96 2 133 133 CD cord-007264-r1w9a6gc 96 3 ± ± NNP cord-007264-r1w9a6gc 96 4 17PMNLs 17PMNLs NNP cord-007264-r1w9a6gc 96 5 / / SYM cord-007264-r1w9a6gc 96 6 lO lO NNP cord-007264-r1w9a6gc 96 7 hpf hpf NN cord-007264-r1w9a6gc 96 8 . . . cord-007264-r1w9a6gc 97 1 Chemoattractant chemoattractant JJ cord-007264-r1w9a6gc 97 2 activity activity NN cord-007264-r1w9a6gc 97 3 was be VBD cord-007264-r1w9a6gc 97 4 also also RB cord-007264-r1w9a6gc 97 5 detected detect VBN cord-007264-r1w9a6gc 97 6 in in IN cord-007264-r1w9a6gc 97 7 human human JJ cord-007264-r1w9a6gc 97 8 foreskin foreskin NN cord-007264-r1w9a6gc 97 9 fibroblasts fibroblast NNS cord-007264-r1w9a6gc 97 10 infected infect VBN cord-007264-r1w9a6gc 97 11 with with IN cord-007264-r1w9a6gc 97 12 R39 R39 NNP cord-007264-r1w9a6gc 97 13 ( ( -LRB- cord-007264-r1w9a6gc 97 14 table table NN cord-007264-r1w9a6gc 97 15 1 1 CD cord-007264-r1w9a6gc 97 16 ) ) -RRB- cord-007264-r1w9a6gc 97 17 . . . cord-007264-r1w9a6gc 98 1 In in IN cord-007264-r1w9a6gc 98 2 contrast contrast NN cord-007264-r1w9a6gc 98 3 , , , cord-007264-r1w9a6gc 98 4 the the DT cord-007264-r1w9a6gc 98 5 chemotactic chemotactic JJ cord-007264-r1w9a6gc 98 6 activity activity NN cord-007264-r1w9a6gc 98 7 detected detect VBN cord-007264-r1w9a6gc 98 8 in in IN cord-007264-r1w9a6gc 98 9 medium medium NN cord-007264-r1w9a6gc 98 10 from from IN cord-007264-r1w9a6gc 98 11 R39-infected R39-infected NNP cord-007264-r1w9a6gc 98 12 HeLa HeLa NNP cord-007264-r1w9a6gc 98 13 cells cell NNS cord-007264-r1w9a6gc 98 14 was be VBD cord-007264-r1w9a6gc 98 15 not not RB cord-007264-r1w9a6gc 98 16 significantly significantly RB cord-007264-r1w9a6gc 98 17 different different JJ cord-007264-r1w9a6gc 98 18 from from IN cord-007264-r1w9a6gc 98 19 the the DT cord-007264-r1w9a6gc 98 20 activity activity NN cord-007264-r1w9a6gc 98 21 in in IN cord-007264-r1w9a6gc 98 22 medium medium NN cord-007264-r1w9a6gc 98 23 from from IN cord-007264-r1w9a6gc 98 24 control control NN cord-007264-r1w9a6gc 98 25 cells cell NNS cord-007264-r1w9a6gc 98 26 , , , cord-007264-r1w9a6gc 98 27 a a DT cord-007264-r1w9a6gc 98 28 result result NN cord-007264-r1w9a6gc 98 29 suggesting suggest VBG cord-007264-r1w9a6gc 98 30 that that IN cord-007264-r1w9a6gc 98 31 elaboration elaboration NN cord-007264-r1w9a6gc 98 32 of of IN cord-007264-r1w9a6gc 98 33 the the DT cord-007264-r1w9a6gc 98 34 chemoattractant chemoattractant NN cord-007264-r1w9a6gc 98 35 is be VBZ cord-007264-r1w9a6gc 98 36 a a DT cord-007264-r1w9a6gc 98 37 property property NN cord-007264-r1w9a6gc 98 38 of of IN cord-007264-r1w9a6gc 98 39 the the DT cord-007264-r1w9a6gc 98 40 infected infected JJ cord-007264-r1w9a6gc 98 41 cell cell NN cord-007264-r1w9a6gc 98 42 . . . cord-007264-r1w9a6gc 99 1 When when WRB cord-007264-r1w9a6gc 99 2 aliquots aliquot NNS cord-007264-r1w9a6gc 99 3 of of IN cord-007264-r1w9a6gc 99 4 medium medium NN cord-007264-r1w9a6gc 99 5 were be VBD cord-007264-r1w9a6gc 99 6 taken take VBN cord-007264-r1w9a6gc 99 7 from from IN cord-007264-r1w9a6gc 99 8 infected infected JJ cord-007264-r1w9a6gc 99 9 cells cell NNS cord-007264-r1w9a6gc 99 10 at at IN cord-007264-r1w9a6gc 99 11 24-h 24-h JJ cord-007264-r1w9a6gc 99 12 intervals interval NNS cord-007264-r1w9a6gc 99 13 , , , cord-007264-r1w9a6gc 99 14 chemoattractant chemoattractant NN cord-007264-r1w9a6gc 99 15 activity activity NN cord-007264-r1w9a6gc 99 16 was be VBD cord-007264-r1w9a6gc 99 17 detectable detectable JJ cord-007264-r1w9a6gc 99 18 24 24 CD cord-007264-r1w9a6gc 99 19 h h NN cord-007264-r1w9a6gc 99 20 after after IN cord-007264-r1w9a6gc 99 21 inoculation inoculation NN cord-007264-r1w9a6gc 99 22 of of IN cord-007264-r1w9a6gc 99 23 virus virus NN cord-007264-r1w9a6gc 99 24 ( ( -LRB- cord-007264-r1w9a6gc 99 25 figure figure NN cord-007264-r1w9a6gc 99 26 1 1 CD cord-007264-r1w9a6gc 99 27 ) ) -RRB- cord-007264-r1w9a6gc 99 28 . . . cord-007264-r1w9a6gc 100 1 The the DT cord-007264-r1w9a6gc 100 2 amount amount NN cord-007264-r1w9a6gc 100 3 of of IN cord-007264-r1w9a6gc 100 4 chemoattractant chemoattractant NN cord-007264-r1w9a6gc 100 5 activity activity NN cord-007264-r1w9a6gc 100 6 increased increase VBD cord-007264-r1w9a6gc 100 7 in in IN cord-007264-r1w9a6gc 100 8 each each DT cord-007264-r1w9a6gc 100 9 subsequent subsequent JJ cord-007264-r1w9a6gc 100 10 aliquot aliquot NN cord-007264-r1w9a6gc 100 11 collected collect VBN cord-007264-r1w9a6gc 100 12 until until IN cord-007264-r1w9a6gc 100 13 the the DT cord-007264-r1w9a6gc 100 14 cpe cpe NNP cord-007264-r1w9a6gc 100 15 was be VBD cord-007264-r1w9a6gc 100 16 complete complete JJ cord-007264-r1w9a6gc 100 17 . . . cord-007264-r1w9a6gc 101 1 Medium medium NN cord-007264-r1w9a6gc 101 2 from from IN cord-007264-r1w9a6gc 101 3 uninfected uninfected JJ cord-007264-r1w9a6gc 101 4 cells cell NNS cord-007264-r1w9a6gc 101 5 disrupted disrupt VBN cord-007264-r1w9a6gc 101 6 by by IN cord-007264-r1w9a6gc 101 7 sonication sonication NN cord-007264-r1w9a6gc 101 8 attracted attract VBD cord-007264-r1w9a6gc 101 9 a a DT cord-007264-r1w9a6gc 101 10 mean mean NN cord-007264-r1w9a6gc 101 11 of of IN cord-007264-r1w9a6gc 101 12 20 20 CD cord-007264-r1w9a6gc 101 13 ± ± NNP cord-007264-r1w9a6gc 101 14 3 3 CD cord-007264-r1w9a6gc 101 15 PMNLs pmnl NNS cord-007264-r1w9a6gc 101 16 / / SYM cord-007264-r1w9a6gc 101 17 lO lO NNP cord-007264-r1w9a6gc 101 18 hpf hpf NN cord-007264-r1w9a6gc 101 19 ( ( -LRB- cord-007264-r1w9a6gc 102 1 P p NN cord-007264-r1w9a6gc 102 2 < < XX cord-007264-r1w9a6gc 102 3 .0001 .0001 . cord-007264-r1w9a6gc 103 1 compared compare VBN cord-007264-r1w9a6gc 103 2 with with IN cord-007264-r1w9a6gc 103 3 medium medium NN cord-007264-r1w9a6gc 103 4 from from IN cord-007264-r1w9a6gc 103 5 infected infected JJ cord-007264-r1w9a6gc 103 6 cells cell NNS cord-007264-r1w9a6gc 103 7 ) ) -RRB- cord-007264-r1w9a6gc 103 8 . . . cord-007264-r1w9a6gc 104 1 Similarly similarly RB cord-007264-r1w9a6gc 104 2 , , , cord-007264-r1w9a6gc 104 3 medium medium NN cord-007264-r1w9a6gc 104 4 from from IN cord-007264-r1w9a6gc 104 5 uninfected uninfected JJ cord-007264-r1w9a6gc 104 6 cells cell NNS cord-007264-r1w9a6gc 104 7 disrupted disrupt VBN cord-007264-r1w9a6gc 104 8 by by IN cord-007264-r1w9a6gc 104 9 freezing freeze VBG cord-007264-r1w9a6gc 104 10 and and CC cord-007264-r1w9a6gc 104 11 thawing thawing NN cord-007264-r1w9a6gc 104 12 attracted attract VBD cord-007264-r1w9a6gc 104 13 a a DT cord-007264-r1w9a6gc 104 14 mean mean NN cord-007264-r1w9a6gc 104 15 of of IN cord-007264-r1w9a6gc 104 16 6 6 CD cord-007264-r1w9a6gc 104 17 ± ± CD cord-007264-r1w9a6gc 104 18 1 1 CD cord-007264-r1w9a6gc 104 19 PMNLs pmnl NNS cord-007264-r1w9a6gc 104 20 / / SYM cord-007264-r1w9a6gc 104 21 lO lO NNP cord-007264-r1w9a6gc 104 22 hpf hpf NN cord-007264-r1w9a6gc 104 23 ( ( -LRB- cord-007264-r1w9a6gc 105 1 P p NN cord-007264-r1w9a6gc 105 2 < < XX cord-007264-r1w9a6gc 105 3 .0001 .0001 . cord-007264-r1w9a6gc 106 1 compared compare VBN cord-007264-r1w9a6gc 106 2 with with IN cord-007264-r1w9a6gc 106 3 Discussion discussion NN cord-007264-r1w9a6gc 107 1 These these DT cord-007264-r1w9a6gc 107 2 experiments experiment NNS cord-007264-r1w9a6gc 107 3 indicate indicate VBP cord-007264-r1w9a6gc 107 4 that that DT cord-007264-r1w9a6gc 107 5 attachment attachment NN cord-007264-r1w9a6gc 107 6 of of IN cord-007264-r1w9a6gc 107 7 rhinovirus rhinovirus NN cord-007264-r1w9a6gc 107 8 to to IN cord-007264-r1w9a6gc 107 9 human human JJ cord-007264-r1w9a6gc 107 10 embryonic embryonic JJ cord-007264-r1w9a6gc 107 11 lung lung NN cord-007264-r1w9a6gc 107 12 fibroblast fibroblast NN cord-007264-r1w9a6gc 107 13 cells cell NNS cord-007264-r1w9a6gc 107 14 results result NNS cord-007264-r1w9a6gc 107 15 in in IN cord-007264-r1w9a6gc 107 16 the the DT cord-007264-r1w9a6gc 107 17 elaboration elaboration NN cord-007264-r1w9a6gc 107 18 of of IN cord-007264-r1w9a6gc 107 19 a a DT cord-007264-r1w9a6gc 107 20 chemoattractant chemoattractant NN cord-007264-r1w9a6gc 107 21 for for IN cord-007264-r1w9a6gc 107 22 human human JJ cord-007264-r1w9a6gc 107 23 PMNLs pmnl NNS cord-007264-r1w9a6gc 107 24 . . . cord-007264-r1w9a6gc 108 1 This this DT cord-007264-r1w9a6gc 108 2 chemoattractant chemoattractant NN cord-007264-r1w9a6gc 108 3 activity activity NN cord-007264-r1w9a6gc 108 4 is be VBZ cord-007264-r1w9a6gc 108 5 not not RB cord-007264-r1w9a6gc 108 6 dependent dependent JJ cord-007264-r1w9a6gc 108 7 upon upon IN cord-007264-r1w9a6gc 108 8 the the DT cord-007264-r1w9a6gc 108 9 presence presence NN cord-007264-r1w9a6gc 108 10 of of IN cord-007264-r1w9a6gc 108 11 complement complement NN cord-007264-r1w9a6gc 108 12 . . . cord-007264-r1w9a6gc 109 1 The the DT cord-007264-r1w9a6gc 109 2 absence absence NN cord-007264-r1w9a6gc 109 3 of of IN cord-007264-r1w9a6gc 109 4 chemoattractant chemoattractant NN cord-007264-r1w9a6gc 109 5 activity activity NN cord-007264-r1w9a6gc 109 6 in in IN cord-007264-r1w9a6gc 109 7 medium medium NN cord-007264-r1w9a6gc 109 8 from from IN cord-007264-r1w9a6gc 109 9 disrupted disrupt VBN cord-007264-r1w9a6gc 109 10 MRC-5 MRC-5 NNP cord-007264-r1w9a6gc 109 11 cells cell NNS cord-007264-r1w9a6gc 109 12 and and CC cord-007264-r1w9a6gc 109 13 HeLa HeLa NNP cord-007264-r1w9a6gc 109 14 cells cell NNS cord-007264-r1w9a6gc 109 15 infected infect VBN cord-007264-r1w9a6gc 109 16 with with IN cord-007264-r1w9a6gc 109 17 R39 R39 NNP cord-007264-r1w9a6gc 109 18 suggests suggest VBZ cord-007264-r1w9a6gc 109 19 that that IN cord-007264-r1w9a6gc 109 20 the the DT cord-007264-r1w9a6gc 109 21 production production NN cord-007264-r1w9a6gc 109 22 of of IN cord-007264-r1w9a6gc 109 23 this this DT cord-007264-r1w9a6gc 109 24 chemoattractant chemoattractant NN cord-007264-r1w9a6gc 109 25 is be VBZ cord-007264-r1w9a6gc 109 26 a a DT cord-007264-r1w9a6gc 109 27 specific specific JJ cord-007264-r1w9a6gc 109 28 response response NN cord-007264-r1w9a6gc 109 29 of of IN cord-007264-r1w9a6gc 109 30 the the DT cord-007264-r1w9a6gc 109 31 fibroblast fibroblast NN cord-007264-r1w9a6gc 109 32 cell cell NN cord-007264-r1w9a6gc 109 33 to to IN cord-007264-r1w9a6gc 109 34 attachment attachment NN cord-007264-r1w9a6gc 109 35 of of IN cord-007264-r1w9a6gc 109 36 virus virus NN cord-007264-r1w9a6gc 109 37 . . . cord-007264-r1w9a6gc 110 1 The the DT cord-007264-r1w9a6gc 110 2 production production NN cord-007264-r1w9a6gc 110 3 of of IN cord-007264-r1w9a6gc 110 4 a a DT cord-007264-r1w9a6gc 110 5 chemoattractant chemoattractant NN cord-007264-r1w9a6gc 110 6 for for IN cord-007264-r1w9a6gc 110 7 PMNLs pmnl NNS cord-007264-r1w9a6gc 110 8 in in IN cord-007264-r1w9a6gc 110 9 response response NN cord-007264-r1w9a6gc 110 10 to to IN cord-007264-r1w9a6gc 110 11 viral viral JJ cord-007264-r1w9a6gc 110 12 infection infection NN cord-007264-r1w9a6gc 110 13 has have VBZ cord-007264-r1w9a6gc 110 14 been be VBN cord-007264-r1w9a6gc 110 15 reported report VBN cord-007264-r1w9a6gc 110 16 previously previously RB cord-007264-r1w9a6gc 110 17 . . . cord-007264-r1w9a6gc 111 1 In in IN cord-007264-r1w9a6gc 111 2 1972 1972 CD cord-007264-r1w9a6gc 111 3 , , , cord-007264-r1w9a6gc 111 4 Ward Ward NNP cord-007264-r1w9a6gc 111 5 and and CC cord-007264-r1w9a6gc 111 6 co co NNS cord-007264-r1w9a6gc 111 7 - - NNS cord-007264-r1w9a6gc 111 8 workers worker NNS cord-007264-r1w9a6gc 111 9 [ [ -LRB- cord-007264-r1w9a6gc 111 10 8 8 CD cord-007264-r1w9a6gc 111 11 ] ] -RRB- cord-007264-r1w9a6gc 111 12 reported report VBD cord-007264-r1w9a6gc 111 13 that that IN cord-007264-r1w9a6gc 111 14 infection infection NN cord-007264-r1w9a6gc 111 15 of of IN cord-007264-r1w9a6gc 111 16 chick chick NN cord-007264-r1w9a6gc 111 17 embryos embryo NNS cord-007264-r1w9a6gc 111 18 with with IN cord-007264-r1w9a6gc 111 19 either either CC cord-007264-r1w9a6gc 111 20 Newcastle Newcastle NNP cord-007264-r1w9a6gc 111 21 disease disease NN cord-007264-r1w9a6gc 111 22 virus virus NN cord-007264-r1w9a6gc 111 23 or or CC cord-007264-r1w9a6gc 111 24 mumps mumps NN cord-007264-r1w9a6gc 111 25 virus virus NN cord-007264-r1w9a6gc 111 26 or or CC cord-007264-r1w9a6gc 111 27 infection infection NN cord-007264-r1w9a6gc 111 28 of of IN cord-007264-r1w9a6gc 111 29 monkey monkey NN cord-007264-r1w9a6gc 111 30 kidney kidney NN cord-007264-r1w9a6gc 111 31 cells cell NNS cord-007264-r1w9a6gc 111 32 with with IN cord-007264-r1w9a6gc 111 33 mumps mumps NN cord-007264-r1w9a6gc 111 34 virus virus NN cord-007264-r1w9a6gc 111 35 resulted result VBD cord-007264-r1w9a6gc 111 36 in in IN cord-007264-r1w9a6gc 111 37 elaboration elaboration NN cord-007264-r1w9a6gc 111 38 of of IN cord-007264-r1w9a6gc 111 39 a a DT cord-007264-r1w9a6gc 111 40 chemoattractant chemoattractant NN cord-007264-r1w9a6gc 111 41 for for IN cord-007264-r1w9a6gc 111 42 PMNLs pmnl NNS cord-007264-r1w9a6gc 111 43 and and CC cord-007264-r1w9a6gc 111 44 macrophages macrophage NNS cord-007264-r1w9a6gc 111 45 . . . cord-007264-r1w9a6gc 112 1 This this DT cord-007264-r1w9a6gc 112 2 chemoattractant chemoattractant NN cord-007264-r1w9a6gc 112 3 was be VBD cord-007264-r1w9a6gc 112 4 produced produce VBN cord-007264-r1w9a6gc 112 5 in in IN cord-007264-r1w9a6gc 112 6 the the DT cord-007264-r1w9a6gc 112 7 presence presence NN cord-007264-r1w9a6gc 112 8 of of IN cord-007264-r1w9a6gc 112 9 serum serum NN cord-007264-r1w9a6gc 112 10 and and CC cord-007264-r1w9a6gc 112 11 appeared appear VBD cord-007264-r1w9a6gc 112 12 to to TO cord-007264-r1w9a6gc 112 13 be be VB cord-007264-r1w9a6gc 112 14 dependent dependent JJ cord-007264-r1w9a6gc 112 15 upon upon IN cord-007264-r1w9a6gc 112 16 the the DT cord-007264-r1w9a6gc 112 17 cell cell NN cord-007264-r1w9a6gc 112 18 line line NN cord-007264-r1w9a6gc 112 19 infected infect VBN cord-007264-r1w9a6gc 112 20 rather rather RB cord-007264-r1w9a6gc 112 21 than than IN cord-007264-r1w9a6gc 112 22 upon upon IN cord-007264-r1w9a6gc 112 23 the the DT cord-007264-r1w9a6gc 112 24 infecting infect VBG cord-007264-r1w9a6gc 112 25 virus virus NN cord-007264-r1w9a6gc 112 26 . . . cord-007264-r1w9a6gc 113 1 Herpes Herpes NNP cord-007264-r1w9a6gc 113 2 simplex simplex NN cord-007264-r1w9a6gc 113 3 virus virus NN cord-007264-r1w9a6gc 113 4 infection infection NN cord-007264-r1w9a6gc 113 5 of of IN cord-007264-r1w9a6gc 113 6 rabbit rabbit NN cord-007264-r1w9a6gc 113 7 kidney kidney NN cord-007264-r1w9a6gc 113 8 cells cell NNS cord-007264-r1w9a6gc 113 9 has have VBZ cord-007264-r1w9a6gc 113 10 been be VBN cord-007264-r1w9a6gc 113 11 reported report VBN cord-007264-r1w9a6gc 113 12 to to TO cord-007264-r1w9a6gc 113 13 produce produce VB cord-007264-r1w9a6gc 113 14 a a DT cord-007264-r1w9a6gc 113 15 chemoattractant chemoattractant NN cord-007264-r1w9a6gc 113 16 for for IN cord-007264-r1w9a6gc 113 17 PMNLs pmnl NNS cord-007264-r1w9a6gc 113 18 by by IN cord-007264-r1w9a6gc 113 19 two two CD cord-007264-r1w9a6gc 113 20 different different JJ cord-007264-r1w9a6gc 113 21 mechanisms mechanism NNS cord-007264-r1w9a6gc 113 22 . . . cord-007264-r1w9a6gc 114 1 Destruction destruction NN cord-007264-r1w9a6gc 114 2 of of IN cord-007264-r1w9a6gc 114 3 the the DT cord-007264-r1w9a6gc 114 4 cell cell NN cord-007264-r1w9a6gc 114 5 monolayer monolayer NN cord-007264-r1w9a6gc 114 6 releases release VBZ cord-007264-r1w9a6gc 114 7 a a DT cord-007264-r1w9a6gc 114 8 factor factor NN cord-007264-r1w9a6gc 114 9 that that WDT cord-007264-r1w9a6gc 114 10 cleavesthe cleavesthe NNP cord-007264-r1w9a6gc 114 11 fifth fifth JJ cord-007264-r1w9a6gc 114 12 component component NN cord-007264-r1w9a6gc 114 13 of of IN cord-007264-r1w9a6gc 114 14 complement complement NN cord-007264-r1w9a6gc 114 15 ( ( -LRB- cord-007264-r1w9a6gc 114 16 C5 C5 NNP cord-007264-r1w9a6gc 114 17 ) ) -RRB- cord-007264-r1w9a6gc 114 18 and and CC cord-007264-r1w9a6gc 114 19 produces produce VBZ cord-007264-r1w9a6gc 114 20 C5a C5a NNS cord-007264-r1w9a6gc 114 21 , , , cord-007264-r1w9a6gc 114 22 a a DT cord-007264-r1w9a6gc 114 23 chemoattractant chemoattractant NN cord-007264-r1w9a6gc 114 24 for for IN cord-007264-r1w9a6gc 114 25 PMNLs pmnl NNS cord-007264-r1w9a6gc 114 26 [ [ -LRB- cord-007264-r1w9a6gc 114 27 6 6 CD cord-007264-r1w9a6gc 114 28 ] ] -RRB- cord-007264-r1w9a6gc 114 29 . . . cord-007264-r1w9a6gc 115 1 A a DT cord-007264-r1w9a6gc 115 2 chemoattractant chemoattractant NN cord-007264-r1w9a6gc 115 3 is be VBZ cord-007264-r1w9a6gc 115 4 also also RB cord-007264-r1w9a6gc 115 5 produced produce VBN cord-007264-r1w9a6gc 115 6 by by IN cord-007264-r1w9a6gc 115 7 the the DT cord-007264-r1w9a6gc 115 8 interaction interaction NN cord-007264-r1w9a6gc 115 9 of of IN cord-007264-r1w9a6gc 115 10 complement complement NN cord-007264-r1w9a6gc 115 11 with with IN cord-007264-r1w9a6gc 115 12 specific specific JJ cord-007264-r1w9a6gc 115 13 antibody antibody NN cord-007264-r1w9a6gc 115 14 to to IN cord-007264-r1w9a6gc 115 15 herpes herpes NNP cord-007264-r1w9a6gc 115 16 simplex simplex NNP cord-007264-r1w9a6gc 115 17 virus virus NN cord-007264-r1w9a6gc 115 18 [ [ -LRB- cord-007264-r1w9a6gc 115 19 7 7 CD cord-007264-r1w9a6gc 115 20 ] ] -RRB- cord-007264-r1w9a6gc 116 1 .The .The . cord-007264-r1w9a6gc 117 1 role role NN cord-007264-r1w9a6gc 117 2 of of IN cord-007264-r1w9a6gc 117 3 chemotactic chemotactic JJ cord-007264-r1w9a6gc 117 4 factors factor NNS cord-007264-r1w9a6gc 117 5 in in IN cord-007264-r1w9a6gc 117 6 the the DT cord-007264-r1w9a6gc 117 7 pathogenesis pathogenesis NN cord-007264-r1w9a6gc 117 8 of of IN cord-007264-r1w9a6gc 117 9 diseases disease NNS cord-007264-r1w9a6gc 117 10 caused cause VBN cord-007264-r1w9a6gc 117 11 by by IN cord-007264-r1w9a6gc 117 12 these these DT cord-007264-r1w9a6gc 117 13 viruses virus NNS cord-007264-r1w9a6gc 117 14 is be VBZ cord-007264-r1w9a6gc 117 15 not not RB cord-007264-r1w9a6gc 117 16 known know VBN cord-007264-r1w9a6gc 117 17 . . . cord-007264-r1w9a6gc 118 1 It -PRON- PRP cord-007264-r1w9a6gc 118 2 has have VBZ cord-007264-r1w9a6gc 118 3 been be VBN cord-007264-r1w9a6gc 118 4 suggested suggest VBN cord-007264-r1w9a6gc 118 5 that that IN cord-007264-r1w9a6gc 118 6 PMNLs pmnl NNS cord-007264-r1w9a6gc 118 7 may may MD cord-007264-r1w9a6gc 118 8 have have VB cord-007264-r1w9a6gc 118 9 a a DT cord-007264-r1w9a6gc 118 10 role role NN cord-007264-r1w9a6gc 118 11 in in IN cord-007264-r1w9a6gc 118 12 the the DT cord-007264-r1w9a6gc 118 13 pathogenesis pathogenesis NN cord-007264-r1w9a6gc 118 14 of of IN cord-007264-r1w9a6gc 118 15 disease disease NN cord-007264-r1w9a6gc 118 16 caused cause VBN cord-007264-r1w9a6gc 118 17 by by IN cord-007264-r1w9a6gc 118 18 viral viral JJ cord-007264-r1w9a6gc 118 19 infection infection NN cord-007264-r1w9a6gc 118 20 of of IN cord-007264-r1w9a6gc 118 21 the the DT cord-007264-r1w9a6gc 118 22 respiratory respiratory JJ cord-007264-r1w9a6gc 118 23 tract tract NN cord-007264-r1w9a6gc 118 24 . . . cord-007264-r1w9a6gc 119 1 On on IN cord-007264-r1w9a6gc 119 2 the the DT cord-007264-r1w9a6gc 119 3 basis basis NN cord-007264-r1w9a6gc 119 4 of of IN cord-007264-r1w9a6gc 119 5 studies study NNS cord-007264-r1w9a6gc 119 6 in in IN cord-007264-r1w9a6gc 119 7 a a DT cord-007264-r1w9a6gc 119 8 ferret ferret JJ cord-007264-r1w9a6gc 119 9 model model NN cord-007264-r1w9a6gc 119 10 , , , cord-007264-r1w9a6gc 119 11 Sweet Sweet NNP cord-007264-r1w9a6gc 119 12 et et FW cord-007264-r1w9a6gc 119 13 al al NNP cord-007264-r1w9a6gc 119 14 . . . cord-007264-r1w9a6gc 120 1 [ [ -LRB- cord-007264-r1w9a6gc 120 2 11 11 CD cord-007264-r1w9a6gc 120 3 ] ] -RRB- cord-007264-r1w9a6gc 120 4 have have VBP cord-007264-r1w9a6gc 120 5 hypothesized hypothesize VBN cord-007264-r1w9a6gc 120 6 that that IN cord-007264-r1w9a6gc 120 7 PMNLs pmnl NNS cord-007264-r1w9a6gc 120 8 interact interact VB cord-007264-r1w9a6gc 120 9 with with IN cord-007264-r1w9a6gc 120 10 influenza influenza NN cord-007264-r1w9a6gc 120 11 virus virus NN cord-007264-r1w9a6gc 120 12 in in IN cord-007264-r1w9a6gc 120 13 the the DT cord-007264-r1w9a6gc 120 14 upper upper JJ cord-007264-r1w9a6gc 120 15 respiratory respiratory JJ cord-007264-r1w9a6gc 120 16 tract tract NN cord-007264-r1w9a6gc 120 17 ; ; : cord-007264-r1w9a6gc 120 18 the the DT cord-007264-r1w9a6gc 120 19 subsequent subsequent JJ cord-007264-r1w9a6gc 120 20 release release NN cord-007264-r1w9a6gc 120 21 of of IN cord-007264-r1w9a6gc 120 22 endogenous endogenous JJ cord-007264-r1w9a6gc 120 23 pyrogen pyrogen NNP cord-007264-r1w9a6gc 120 24 produces produce VBZ cord-007264-r1w9a6gc 120 25 the the DT cord-007264-r1w9a6gc 120 26 systemic systemic JJ cord-007264-r1w9a6gc 120 27 symptoms symptom NNS cord-007264-r1w9a6gc 120 28 of of IN cord-007264-r1w9a6gc 120 29 these these DT cord-007264-r1w9a6gc 120 30 infections infection NNS cord-007264-r1w9a6gc 120 31 . . . cord-007264-r1w9a6gc 121 1 Faden Faden NNP cord-007264-r1w9a6gc 121 2 et et NNP cord-007264-r1w9a6gc 121 3 al al NNP cord-007264-r1w9a6gc 121 4 . . . cord-007264-r1w9a6gc 122 1 [ [ -LRB- cord-007264-r1w9a6gc 122 2 12 12 CD cord-007264-r1w9a6gc 122 3 ] ] -RRB- cord-007264-r1w9a6gc 122 4 have have VBP cord-007264-r1w9a6gc 122 5 reported report VBN cord-007264-r1w9a6gc 122 6 thatRSV thatrsv NN cord-007264-r1w9a6gc 122 7 antibody antibody NN cord-007264-r1w9a6gc 122 8 complexes complex NNS cord-007264-r1w9a6gc 122 9 activate activate VBP cord-007264-r1w9a6gc 122 10 PMNLs pmnl NNS cord-007264-r1w9a6gc 122 11 and and CC cord-007264-r1w9a6gc 122 12 have have VBP cord-007264-r1w9a6gc 122 13 suggested suggest VBN cord-007264-r1w9a6gc 122 14 that that IN cord-007264-r1w9a6gc 122 15 the the DT cord-007264-r1w9a6gc 122 16 products product NNS cord-007264-r1w9a6gc 122 17 of of IN cord-007264-r1w9a6gc 122 18 this this DT cord-007264-r1w9a6gc 122 19 activation activation NN cord-007264-r1w9a6gc 122 20 may may MD cord-007264-r1w9a6gc 122 21 be be VB cord-007264-r1w9a6gc 122 22 responsible responsible JJ cord-007264-r1w9a6gc 122 23 for for IN cord-007264-r1w9a6gc 122 24 some some DT cord-007264-r1w9a6gc 122 25 of of IN cord-007264-r1w9a6gc 122 26 the the DT cord-007264-r1w9a6gc 122 27 symptoms symptom NNS cord-007264-r1w9a6gc 122 28 of of IN cord-007264-r1w9a6gc 122 29 respiratory respiratory JJ cord-007264-r1w9a6gc 122 30 syncytial syncytial JJ cord-007264-r1w9a6gc 122 31 virus virus NN cord-007264-r1w9a6gc 122 32 infection infection NN cord-007264-r1w9a6gc 122 33 . . . cord-007264-r1w9a6gc 123 1 The the DT cord-007264-r1w9a6gc 123 2 pathogenesis pathogenesis NN cord-007264-r1w9a6gc 123 3 of of IN cord-007264-r1w9a6gc 123 4 the the DT cord-007264-r1w9a6gc 123 5 symptoms symptom NNS cord-007264-r1w9a6gc 123 6 produced produce VBN cord-007264-r1w9a6gc 123 7 by by IN cord-007264-r1w9a6gc 123 8 rhinovirus rhinovirus NN cord-007264-r1w9a6gc 123 9 infection infection NN cord-007264-r1w9a6gc 123 10 of of IN cord-007264-r1w9a6gc 123 11 the the DT cord-007264-r1w9a6gc 123 12 upper upper JJ cord-007264-r1w9a6gc 123 13 respiratory respiratory JJ cord-007264-r1w9a6gc 123 14 tract tract NN cord-007264-r1w9a6gc 123 15 is be VBZ cord-007264-r1w9a6gc 123 16 not not RB cord-007264-r1w9a6gc 123 17 known know VBN cord-007264-r1w9a6gc 123 18 . . . cord-007264-r1w9a6gc 124 1 Cytopathologic Cytopathologic NNP cord-007264-r1w9a6gc 124 2 changes change NNS cord-007264-r1w9a6gc 124 3 in in IN cord-007264-r1w9a6gc 124 4 the the DT cord-007264-r1w9a6gc 124 5 nasal nasal NN cord-007264-r1w9a6gc 124 6 mucosa mucosa NN cord-007264-r1w9a6gc 124 7 appear appear VBP cord-007264-r1w9a6gc 124 8 to to TO cord-007264-r1w9a6gc 124 9 be be VB cord-007264-r1w9a6gc 124 10 minimal minimal JJ cord-007264-r1w9a6gc 124 11 during during IN cord-007264-r1w9a6gc 124 12 rhinovirus rhinovirus JJ cord-007264-r1w9a6gc 124 13 colds cold NNS cord-007264-r1w9a6gc 124 14 . . . cord-007264-r1w9a6gc 125 1 Two two CD cord-007264-r1w9a6gc 125 2 different different JJ cord-007264-r1w9a6gc 125 3 studies study NNS cord-007264-r1w9a6gc 125 4 of of IN cord-007264-r1w9a6gc 125 5 biopsy biopsy NN cord-007264-r1w9a6gc 125 6 specimens specimen NNS cord-007264-r1w9a6gc 125 7 from from IN cord-007264-r1w9a6gc 125 8 human human JJ cord-007264-r1w9a6gc 125 9 volunteers volunteer NNS cord-007264-r1w9a6gc 125 10 have have VBP cord-007264-r1w9a6gc 125 11 found find VBN cord-007264-r1w9a6gc 125 12 no no DT cord-007264-r1w9a6gc 125 13 consistent consistent JJ cord-007264-r1w9a6gc 125 14 changes change NNS cord-007264-r1w9a6gc 125 15 of of IN cord-007264-r1w9a6gc 125 16 the the DT cord-007264-r1w9a6gc 125 17 nasal nasal NN cord-007264-r1w9a6gc 125 18 epithelium epithelium NN cord-007264-r1w9a6gc 125 19 in in IN cord-007264-r1w9a6gc 125 20 rhinovirus rhinovirus NN cord-007264-r1w9a6gc 125 21 infection infection NN cord-007264-r1w9a6gc 125 22 [ [ -LRB- cord-007264-r1w9a6gc 125 23 4 4 CD cord-007264-r1w9a6gc 125 24 , , , cord-007264-r1w9a6gc 125 25 13 13 CD cord-007264-r1w9a6gc 125 26 ] ] -RRB- cord-007264-r1w9a6gc 125 27 . . . cord-007264-r1w9a6gc 126 1 Examination examination NN cord-007264-r1w9a6gc 126 2 of of IN cord-007264-r1w9a6gc 126 3 the the DT cord-007264-r1w9a6gc 126 4 cells cell NNS cord-007264-r1w9a6gc 126 5 present present JJ cord-007264-r1w9a6gc 126 6 in in IN cord-007264-r1w9a6gc 126 7 the the DT cord-007264-r1w9a6gc 126 8 nasal nasal NN cord-007264-r1w9a6gc 126 9 secretions secretion NNS cord-007264-r1w9a6gc 126 10 of of IN cord-007264-r1w9a6gc 126 11 infected infected JJ cord-007264-r1w9a6gc 126 12 volunteers volunteer NNS cord-007264-r1w9a6gc 126 13 revealed reveal VBD cord-007264-r1w9a6gc 126 14 that that IN cord-007264-r1w9a6gc 126 15 infected infected JJ cord-007264-r1w9a6gc 126 16 ciliated ciliated JJ cord-007264-r1w9a6gc 126 17 cells cell NNS cord-007264-r1w9a6gc 126 18 are be VBP cord-007264-r1w9a6gc 126 19 shed shed VBN cord-007264-r1w9a6gc 126 20 from from IN cord-007264-r1w9a6gc 126 21 the the DT cord-007264-r1w9a6gc 126 22 nasal nasal NN cord-007264-r1w9a6gc 126 23 epithelium epithelium NN cord-007264-r1w9a6gc 126 24 during during IN cord-007264-r1w9a6gc 126 25 rhinovirus rhinovirus NN cord-007264-r1w9a6gc 126 26 colds cold NNS cord-007264-r1w9a6gc 126 27 [ [ -LRB- cord-007264-r1w9a6gc 126 28 2 2 CD cord-007264-r1w9a6gc 126 29 ] ] -RRB- cord-007264-r1w9a6gc 126 30 ; ; : cord-007264-r1w9a6gc 126 31 however however RB cord-007264-r1w9a6gc 126 32 , , , cord-007264-r1w9a6gc 126 33 the the DT cord-007264-r1w9a6gc 126 34 low low JJ cord-007264-r1w9a6gc 126 35 number number NN cord-007264-r1w9a6gc 126 36 of of IN cord-007264-r1w9a6gc 126 37 cells cell NNS cord-007264-r1w9a6gc 126 38 observed observe VBN cord-007264-r1w9a6gc 126 39 is be VBZ cord-007264-r1w9a6gc 126 40 consistent consistent JJ cord-007264-r1w9a6gc 126 41 with with IN cord-007264-r1w9a6gc 126 42 the the DT cord-007264-r1w9a6gc 126 43 absence absence NN cord-007264-r1w9a6gc 126 44 of of IN cord-007264-r1w9a6gc 126 45 findings finding NNS cord-007264-r1w9a6gc 126 46 in in IN cord-007264-r1w9a6gc 126 47 the the DT cord-007264-r1w9a6gc 126 48 biopsy biopsy NNP cord-007264-r1w9a6gc 126 49 studies study NNS cord-007264-r1w9a6gc 126 50 . . . cord-007264-r1w9a6gc 127 1 The the DT cord-007264-r1w9a6gc 127 2 absence absence NN cord-007264-r1w9a6gc 127 3 of of IN cord-007264-r1w9a6gc 127 4 histopathologic histopathologic JJ cord-007264-r1w9a6gc 127 5 findings finding NNS cord-007264-r1w9a6gc 127 6 led lead VBD cord-007264-r1w9a6gc 127 7 to to IN cord-007264-r1w9a6gc 127 8 the the DT cord-007264-r1w9a6gc 127 9 suggestion suggestion NN cord-007264-r1w9a6gc 127 10 that that IN cord-007264-r1w9a6gc 127 11 the the DT cord-007264-r1w9a6gc 127 12 viral viral JJ cord-007264-r1w9a6gc 127 13 infection infection NN cord-007264-r1w9a6gc 127 14 triggers trigger VBZ cord-007264-r1w9a6gc 127 15 inflammatory inflammatory JJ cord-007264-r1w9a6gc 127 16 responses response NNS cord-007264-r1w9a6gc 127 17 that that WDT cord-007264-r1w9a6gc 127 18 result result VBP cord-007264-r1w9a6gc 127 19 in in IN cord-007264-r1w9a6gc 127 20 the the DT cord-007264-r1w9a6gc 127 21 production production NN cord-007264-r1w9a6gc 127 22 of of IN cord-007264-r1w9a6gc 127 23 symptoms symptom NNS cord-007264-r1w9a6gc 127 24 [ [ -LRB- cord-007264-r1w9a6gc 127 25 2 2 CD cord-007264-r1w9a6gc 127 26 , , , cord-007264-r1w9a6gc 127 27 3 3 CD cord-007264-r1w9a6gc 127 28 ] ] -RRB- cord-007264-r1w9a6gc 127 29 . . . cord-007264-r1w9a6gc 128 1 In in IN cord-007264-r1w9a6gc 128 2 1984 1984 CD cord-007264-r1w9a6gc 128 3 , , , cord-007264-r1w9a6gc 128 4 Winther Winther NNP cord-007264-r1w9a6gc 128 5 et et NNP cord-007264-r1w9a6gc 128 6 al al NNP cord-007264-r1w9a6gc 128 7 . . . cord-007264-r1w9a6gc 129 1 [ [ -LRB- cord-007264-r1w9a6gc 129 2 4 4 CD cord-007264-r1w9a6gc 129 3 ] ] -RRB- cord-007264-r1w9a6gc 129 4 reported report VBD cord-007264-r1w9a6gc 129 5 that that IN cord-007264-r1w9a6gc 129 6 the the DT cord-007264-r1w9a6gc 129 7 number number NN cord-007264-r1w9a6gc 129 8 of of IN cord-007264-r1w9a6gc 129 9 PMNLs pmnl NNS cord-007264-r1w9a6gc 129 10 in in IN cord-007264-r1w9a6gc 129 11 the the DT cord-007264-r1w9a6gc 129 12 nasal nasal NN cord-007264-r1w9a6gc 129 13 mucosa mucosa NN cord-007264-r1w9a6gc 129 14 was be VBD cord-007264-r1w9a6gc 129 15 significantly significantly RB cord-007264-r1w9a6gc 129 16 greater great JJR cord-007264-r1w9a6gc 129 17 in in IN cord-007264-r1w9a6gc 129 18 biopsy biopsy NN cord-007264-r1w9a6gc 129 19 specimens specimen NNS cord-007264-r1w9a6gc 129 20 taken take VBN cord-007264-r1w9a6gc 129 21 from from IN cord-007264-r1w9a6gc 129 22 volunteers volunteer NNS cord-007264-r1w9a6gc 129 23 during during IN cord-007264-r1w9a6gc 129 24 symptomatic symptomatic JJ cord-007264-r1w9a6gc 129 25 upper upper JJ cord-007264-r1w9a6gc 129 26 - - HYPH cord-007264-r1w9a6gc 129 27 respiratory respiratory JJ cord-007264-r1w9a6gc 129 28 - - HYPH cord-007264-r1w9a6gc 129 29 tract tract NN cord-007264-r1w9a6gc 129 30 infections infection NNS cord-007264-r1w9a6gc 129 31 than than IN cord-007264-r1w9a6gc 129 32 in in IN cord-007264-r1w9a6gc 129 33 specimens specimen NNS cord-007264-r1w9a6gc 129 34 taken take VBN cord-007264-r1w9a6gc 129 35 during during IN cord-007264-r1w9a6gc 129 36 convalescence convalescence NN cord-007264-r1w9a6gc 129 37 or or CC cord-007264-r1w9a6gc 129 38 from from IN cord-007264-r1w9a6gc 129 39 asymptomatic asymptomatic JJ cord-007264-r1w9a6gc 129 40 control control NN cord-007264-r1w9a6gc 129 41 subjects subject NNS cord-007264-r1w9a6gc 129 42 . . . cord-007264-r1w9a6gc 130 1 A a DT cord-007264-r1w9a6gc 130 2 study study NN cord-007264-r1w9a6gc 130 3 in in IN cord-007264-r1w9a6gc 130 4 volunteers volunteer NNS cord-007264-r1w9a6gc 130 5 with with IN cord-007264-r1w9a6gc 130 6 experimental experimental JJ cord-007264-r1w9a6gc 130 7 rhinovirus rhinovirus NN cord-007264-r1w9a6gc 130 8 colds cold NNS cord-007264-r1w9a6gc 130 9 re- re- RB cord-007264-r1w9a6gc 131 1 ( ( -LRB- cord-007264-r1w9a6gc 131 2 table table NN cord-007264-r1w9a6gc 131 3 2 2 CD cord-007264-r1w9a6gc 131 4 ) ) -RRB- cord-007264-r1w9a6gc 131 5 . . . cord-007264-r1w9a6gc 132 1 In in IN cord-007264-r1w9a6gc 132 2 contrast contrast NN cord-007264-r1w9a6gc 132 3 , , , cord-007264-r1w9a6gc 132 4 medium medium NN cord-007264-r1w9a6gc 132 5 from from IN cord-007264-r1w9a6gc 132 6 HeLa HeLa NNP cord-007264-r1w9a6gc 132 7 cellsinfected cellsinfecte VBN cord-007264-r1w9a6gc 132 8 with with IN cord-007264-r1w9a6gc 132 9 RSV RSV NNP cord-007264-r1w9a6gc 132 10 attracted attract VBD cord-007264-r1w9a6gc 132 11 9 9 CD cord-007264-r1w9a6gc 132 12 PMNLs pmnl NNS cord-007264-r1w9a6gc 132 13 / / SYM cord-007264-r1w9a6gc 132 14 lO lO NNP cord-007264-r1w9a6gc 132 15 hpf hpf NN cord-007264-r1w9a6gc 132 16 , , , cord-007264-r1w9a6gc 132 17 compared compare VBN cord-007264-r1w9a6gc 132 18 with with IN cord-007264-r1w9a6gc 132 19 7 7 CD cord-007264-r1w9a6gc 132 20 PMNLs/ PMNLs/ NNP cord-007264-r1w9a6gc 133 1 lO lO NNP cord-007264-r1w9a6gc 133 2 hpf hpf NN cord-007264-r1w9a6gc 133 3 attracted attract VBN cord-007264-r1w9a6gc 133 4 by by IN cord-007264-r1w9a6gc 133 5 medium medium NN cord-007264-r1w9a6gc 133 6 from from IN cord-007264-r1w9a6gc 133 7 control control NN cord-007264-r1w9a6gc 133 8 tubes tube NNS cord-007264-r1w9a6gc 133 9 . . . cord-007264-r1w9a6gc 134 1 These these DT cord-007264-r1w9a6gc 134 2 results result NNS cord-007264-r1w9a6gc 134 3 indicate indicate VBP cord-007264-r1w9a6gc 134 4 that that IN cord-007264-r1w9a6gc 134 5 infection infection NN cord-007264-r1w9a6gc 134 6 of of IN cord-007264-r1w9a6gc 134 7 fibroblast fibroblast NN cord-007264-r1w9a6gc 134 8 cells cell NNS cord-007264-r1w9a6gc 134 9 with with IN cord-007264-r1w9a6gc 134 10 respiratory respiratory JJ cord-007264-r1w9a6gc 134 11 viruses virus NNS cord-007264-r1w9a6gc 134 12 other other JJ cord-007264-r1w9a6gc 134 13 than than IN cord-007264-r1w9a6gc 134 14 rhinovirus rhinovirus NN cord-007264-r1w9a6gc 134 15 is be VBZ cord-007264-r1w9a6gc 134 16 also also RB cord-007264-r1w9a6gc 134 17 associated associate VBN cord-007264-r1w9a6gc 134 18 with with IN cord-007264-r1w9a6gc 134 19 elaboration elaboration NN cord-007264-r1w9a6gc 134 20 of of IN cord-007264-r1w9a6gc 134 21 a a DT cord-007264-r1w9a6gc 134 22 chemoattractant chemoattractant NN cord-007264-r1w9a6gc 134 23 . . . cord-007264-r1w9a6gc 135 1 It -PRON- PRP cord-007264-r1w9a6gc 135 2 remains remain VBZ cord-007264-r1w9a6gc 135 3 to to TO cord-007264-r1w9a6gc 135 4 be be VB cord-007264-r1w9a6gc 135 5 determined determine VBN cord-007264-r1w9a6gc 135 6 whether whether IN cord-007264-r1w9a6gc 135 7 the the DT cord-007264-r1w9a6gc 135 8 chemoattractants chemoattractant NNS cord-007264-r1w9a6gc 135 9 produced produce VBN cord-007264-r1w9a6gc 135 10 by by IN cord-007264-r1w9a6gc 135 11 infection infection NN cord-007264-r1w9a6gc 135 12 with with IN cord-007264-r1w9a6gc 135 13 these these DT cord-007264-r1w9a6gc 135 14 viruses virus NNS cord-007264-r1w9a6gc 135 15 are be VBP cord-007264-r1w9a6gc 135 16 identical identical JJ cord-007264-r1w9a6gc 135 17 . . . cord-007264-r1w9a6gc 136 1 vealed veale VBD cord-007264-r1w9a6gc 136 2 that that IN cord-007264-r1w9a6gc 136 3 the the DT cord-007264-r1w9a6gc 136 4 number number NN cord-007264-r1w9a6gc 136 5 of of IN cord-007264-r1w9a6gc 136 6 PMNLs pmnl NNS cord-007264-r1w9a6gc 136 7 in in IN cord-007264-r1w9a6gc 136 8 the the DT cord-007264-r1w9a6gc 136 9 nasal nasal NN cord-007264-r1w9a6gc 136 10 mucosa mucosa NN cord-007264-r1w9a6gc 136 11 increased increase VBD cord-007264-r1w9a6gc 136 12 significantly significantly RB cord-007264-r1w9a6gc 136 13 following follow VBG cord-007264-r1w9a6gc 136 14 inoculation inoculation NN cord-007264-r1w9a6gc 136 15 with with IN cord-007264-r1w9a6gc 136 16 virus virus NN cord-007264-r1w9a6gc 136 17 and and CC cord-007264-r1w9a6gc 136 18 that that IN cord-007264-r1w9a6gc 136 19 the the DT cord-007264-r1w9a6gc 136 20 increase increase NN cord-007264-r1w9a6gc 136 21 occurred occur VBD cord-007264-r1w9a6gc 136 22 before before IN cord-007264-r1w9a6gc 136 23 symptoms symptom NNS cord-007264-r1w9a6gc 136 24 were be VBD cord-007264-r1w9a6gc 136 25 reported report VBN cord-007264-r1w9a6gc 136 26 [ [ -LRB- cord-007264-r1w9a6gc 136 27 5 5 CD cord-007264-r1w9a6gc 136 28 ] ] -RRB- cord-007264-r1w9a6gc 136 29 . . . cord-007264-r1w9a6gc 137 1 A a DT cord-007264-r1w9a6gc 137 2 later later JJ cord-007264-r1w9a6gc 137 3 study study NN cord-007264-r1w9a6gc 137 4 suggests suggest VBZ cord-007264-r1w9a6gc 137 5 that that IN cord-007264-r1w9a6gc 137 6 the the DT cord-007264-r1w9a6gc 137 7 concentration concentration NN cord-007264-r1w9a6gc 137 8 of of IN cord-007264-r1w9a6gc 137 9 PMNLs pmnl NNS cord-007264-r1w9a6gc 137 10 in in IN cord-007264-r1w9a6gc 137 11 nasal nasal NN cord-007264-r1w9a6gc 137 12 secretions secretion NNS cord-007264-r1w9a6gc 137 13 also also RB cord-007264-r1w9a6gc 137 14 increases increase VBZ cord-007264-r1w9a6gc 137 15 during during IN cord-007264-r1w9a6gc 137 16 rhinovirus rhinovirus NN cord-007264-r1w9a6gc 137 17 colds cold NNS cord-007264-r1w9a6gc 137 18 ( ( -LRB- cord-007264-r1w9a6gc 137 19 1 1 CD cord-007264-r1w9a6gc 137 20 . . . cord-007264-r1w9a6gc 138 1 O. O. NNP cord-007264-r1w9a6gc 138 2 Hendley Hendley NNP cord-007264-r1w9a6gc 138 3 , , , cord-007264-r1w9a6gc 138 4 personal personal JJ cord-007264-r1w9a6gc 138 5 communication communication NN cord-007264-r1w9a6gc 138 6 ) ) -RRB- cord-007264-r1w9a6gc 138 7 . . . cord-007264-r1w9a6gc 139 1 These these DT cord-007264-r1w9a6gc 139 2 data datum NNS cord-007264-r1w9a6gc 139 3 are be VBP cord-007264-r1w9a6gc 139 4 consistent consistent JJ cord-007264-r1w9a6gc 139 5 with with IN cord-007264-r1w9a6gc 139 6 the the DT cord-007264-r1w9a6gc 139 7 hypothesis hypothesis NN cord-007264-r1w9a6gc 139 8 that that IN cord-007264-r1w9a6gc 139 9 symptoms symptom NNS cord-007264-r1w9a6gc 139 10 of of IN cord-007264-r1w9a6gc 139 11 the the DT cord-007264-r1w9a6gc 139 12 common common JJ cord-007264-r1w9a6gc 139 13 cold cold NN cord-007264-r1w9a6gc 139 14 are be VBP cord-007264-r1w9a6gc 139 15 a a DT cord-007264-r1w9a6gc 139 16 result result NN cord-007264-r1w9a6gc 139 17 of of IN cord-007264-r1w9a6gc 139 18 the the DT cord-007264-r1w9a6gc 139 19 host host NN cord-007264-r1w9a6gc 139 20 response response NN cord-007264-r1w9a6gc 139 21 to to IN cord-007264-r1w9a6gc 139 22 the the DT cord-007264-r1w9a6gc 139 23 virus virus NN cord-007264-r1w9a6gc 139 24 and and CC cord-007264-r1w9a6gc 139 25 suggest suggest VBP cord-007264-r1w9a6gc 139 26 that that IN cord-007264-r1w9a6gc 139 27 PMNLs pmnl NNS cord-007264-r1w9a6gc 139 28 may may MD cord-007264-r1w9a6gc 139 29 be be VB cord-007264-r1w9a6gc 139 30 an an DT cord-007264-r1w9a6gc 139 31 important important JJ cord-007264-r1w9a6gc 139 32 component component NN cord-007264-r1w9a6gc 139 33 of of IN cord-007264-r1w9a6gc 139 34 this this DT cord-007264-r1w9a6gc 139 35 response response NN cord-007264-r1w9a6gc 139 36 . . . cord-007264-r1w9a6gc 140 1 The the DT cord-007264-r1w9a6gc 140 2 observation observation NN cord-007264-r1w9a6gc 140 3 that that IN cord-007264-r1w9a6gc 140 4 rhinovirus rhinovirus NN cord-007264-r1w9a6gc 140 5 infection infection NN cord-007264-r1w9a6gc 140 6 of of IN cord-007264-r1w9a6gc 140 7 human human JJ cord-007264-r1w9a6gc 140 8 fibroblast fibroblast NN cord-007264-r1w9a6gc 140 9 cells cell NNS cord-007264-r1w9a6gc 140 10 results result NNS cord-007264-r1w9a6gc 140 11 in in IN cord-007264-r1w9a6gc 140 12 production production NN cord-007264-r1w9a6gc 140 13 of of IN cord-007264-r1w9a6gc 140 14 a a DT cord-007264-r1w9a6gc 140 15 chemoattractant chemoattractant NN cord-007264-r1w9a6gc 140 16 for for IN cord-007264-r1w9a6gc 140 17 PMNLs pmnl NNS cord-007264-r1w9a6gc 140 18 provides provide VBZ cord-007264-r1w9a6gc 140 19 a a DT cord-007264-r1w9a6gc 140 20 potential potential JJ cord-007264-r1w9a6gc 140 21 explanation explanation NN cord-007264-r1w9a6gc 140 22 for for IN cord-007264-r1w9a6gc 140 23 the the DT cord-007264-r1w9a6gc 140 24 attraction attraction NN cord-007264-r1w9a6gc 140 25 of of IN cord-007264-r1w9a6gc 140 26 PMNLs pmnl NNS cord-007264-r1w9a6gc 140 27 to to IN cord-007264-r1w9a6gc 140 28 the the DT cord-007264-r1w9a6gc 140 29 nasal nasal NN cord-007264-r1w9a6gc 140 30 mucosa mucosa JJ cord-007264-r1w9a6gc 140 31 during during IN cord-007264-r1w9a6gc 140 32 rhinovirus rhinovirus JJ cord-007264-r1w9a6gc 140 33 colds cold NNS cord-007264-r1w9a6gc 140 34 . . . cord-007264-r1w9a6gc 141 1 Characterization characterization NN cord-007264-r1w9a6gc 141 2 of of IN cord-007264-r1w9a6gc 141 3 this this DT cord-007264-r1w9a6gc 141 4 chemoattractant chemoattractant NN cord-007264-r1w9a6gc 141 5 may may MD cord-007264-r1w9a6gc 141 6 provide provide VB cord-007264-r1w9a6gc 141 7 important important JJ cord-007264-r1w9a6gc 141 8 information information NN cord-007264-r1w9a6gc 141 9 about about IN cord-007264-r1w9a6gc 141 10 the the DT cord-007264-r1w9a6gc 141 11 pathogenesis pathogenesis NN cord-007264-r1w9a6gc 141 12 of of IN cord-007264-r1w9a6gc 141 13 viral viral JJ cord-007264-r1w9a6gc 141 14 infection infection NN cord-007264-r1w9a6gc 141 15 of of IN cord-007264-r1w9a6gc 141 16 the the DT cord-007264-r1w9a6gc 141 17 respiratory respiratory JJ cord-007264-r1w9a6gc 141 18 tract tract NN cord-007264-r1w9a6gc 141 19 . . . cord-007264-r1w9a6gc 142 1 Acute acute JJ cord-007264-r1w9a6gc 142 2 respiratory respiratory JJ cord-007264-r1w9a6gc 142 3 illness illness NN cord-007264-r1w9a6gc 142 4 in in IN cord-007264-r1w9a6gc 142 5 an an DT cord-007264-r1w9a6gc 142 6 American american JJ cord-007264-r1w9a6gc 142 7 community community NN cord-007264-r1w9a6gc 142 8 : : : cord-007264-r1w9a6gc 142 9 the the DT cord-007264-r1w9a6gc 142 10 Tecumseh Tecumseh NNP cord-007264-r1w9a6gc 142 11 study study NN cord-007264-r1w9a6gc 142 12 Shedding shedding NN cord-007264-r1w9a6gc 142 13 of of IN cord-007264-r1w9a6gc 142 14 infected infected JJ cord-007264-r1w9a6gc 142 15 ciliated ciliated JJ cord-007264-r1w9a6gc 142 16 epithelial epithelial JJ cord-007264-r1w9a6gc 142 17 cells cell NNS cord-007264-r1w9a6gc 142 18 in in IN cord-007264-r1w9a6gc 142 19 rhinovirus rhinovirus NN cord-007264-r1w9a6gc 142 20 colds cold NNS cord-007264-r1w9a6gc 142 21 Rhinovirus Rhinovirus NNP cord-007264-r1w9a6gc 142 22 colds cold NNS cord-007264-r1w9a6gc 142 23 : : : cord-007264-r1w9a6gc 142 24 immunology immunology NN cord-007264-r1w9a6gc 142 25 and and CC cord-007264-r1w9a6gc 142 26 pathogenesis pathogenesis NN cord-007264-r1w9a6gc 142 27 Light light NN cord-007264-r1w9a6gc 142 28 and and CC cord-007264-r1w9a6gc 142 29 scanning scanning NN cord-007264-r1w9a6gc 142 30 electron electron NN cord-007264-r1w9a6gc 142 31 microscopy microscopy NN cord-007264-r1w9a6gc 142 32 of of IN cord-007264-r1w9a6gc 142 33 nasal nasal JJ cord-007264-r1w9a6gc 142 34 biopsy biopsy NN cord-007264-r1w9a6gc 142 35 material material NN cord-007264-r1w9a6gc 142 36 from from IN cord-007264-r1w9a6gc 142 37 Turner Turner NNP cord-007264-r1w9a6gc 142 38 patients patient NNS cord-007264-r1w9a6gc 142 39 with with IN cord-007264-r1w9a6gc 142 40 naturally naturally RB cord-007264-r1w9a6gc 142 41 acquired acquire VBN cord-007264-r1w9a6gc 142 42 common common JJ cord-007264-r1w9a6gc 142 43 colds cold NNS cord-007264-r1w9a6gc 142 44 Histopathologic Histopathologic NNP cord-007264-r1w9a6gc 142 45 examination examination NN cord-007264-r1w9a6gc 142 46 and and CC cord-007264-r1w9a6gc 142 47 enumeration enumeration NN cord-007264-r1w9a6gc 142 48 of of IN cord-007264-r1w9a6gc 142 49 polymorphonuclear polymorphonuclear NNP cord-007264-r1w9a6gc 142 50 leukocytesin leukocytesin NNP cord-007264-r1w9a6gc 143 1 the the DT cord-007264-r1w9a6gc 143 2 nasal nasal NN cord-007264-r1w9a6gc 143 3 mucosa mucosa JJ cord-007264-r1w9a6gc 143 4 during during IN cord-007264-r1w9a6gc 143 5 experimental experimental JJ cord-007264-r1w9a6gc 143 6 rhinovirus rhinovirus NN cord-007264-r1w9a6gc 143 7 colds cold NNS cord-007264-r1w9a6gc 143 8 Inflammation inflammation NN cord-007264-r1w9a6gc 143 9 and and CC cord-007264-r1w9a6gc 143 10 herpes herpes NN cord-007264-r1w9a6gc 143 11 simplex simplex NNP cord-007264-r1w9a6gc 143 12 virus virus NN cord-007264-r1w9a6gc 143 13 : : : cord-007264-r1w9a6gc 143 14 release release NN cord-007264-r1w9a6gc 143 15 of of IN cord-007264-r1w9a6gc 143 16 a a DT cord-007264-r1w9a6gc 143 17 chemotaxis chemotaxis NN cord-007264-r1w9a6gc 143 18 - - HYPH cord-007264-r1w9a6gc 143 19 generating generate VBG cord-007264-r1w9a6gc 143 20 factor factor NN cord-007264-r1w9a6gc 143 21 from from IN cord-007264-r1w9a6gc 143 22 infected infected JJ cord-007264-r1w9a6gc 143 23 cells cell NNS cord-007264-r1w9a6gc 143 24 Inflammation inflammation NN cord-007264-r1w9a6gc 143 25 and and CC cord-007264-r1w9a6gc 143 26 viral viral JJ cord-007264-r1w9a6gc 143 27 infection infection NN cord-007264-r1w9a6gc 143 28 : : : cord-007264-r1w9a6gc 143 29 chemotactic chemotactic JJ cord-007264-r1w9a6gc 143 30 activity activity NN cord-007264-r1w9a6gc 143 31 resulting result VBG cord-007264-r1w9a6gc 143 32 from from IN cord-007264-r1w9a6gc 143 33 the the DT cord-007264-r1w9a6gc 143 34 interaction interaction NN cord-007264-r1w9a6gc 143 35 of of IN cord-007264-r1w9a6gc 143 36 antiviral antiviral JJ cord-007264-r1w9a6gc 143 37 antibody antibody NN cord-007264-r1w9a6gc 143 38 and and CC cord-007264-r1w9a6gc 143 39 complement complement VB cord-007264-r1w9a6gc 143 40 with with IN cord-007264-r1w9a6gc 143 41 cells cell NNS cord-007264-r1w9a6gc 143 42 infected infect VBN cord-007264-r1w9a6gc 143 43 with with IN cord-007264-r1w9a6gc 143 44 herpes herpes NN cord-007264-r1w9a6gc 143 45 simplex simplex NN cord-007264-r1w9a6gc 143 46 virus virus NN cord-007264-r1w9a6gc 143 47 Leukotactic leukotactic JJ cord-007264-r1w9a6gc 143 48 factors factor NNS cord-007264-r1w9a6gc 143 49 elaborated elaborate VBN cord-007264-r1w9a6gc 143 50 by by IN cord-007264-r1w9a6gc 143 51 virus virus NN cord-007264-r1w9a6gc 143 52 - - HYPH cord-007264-r1w9a6gc 143 53 infected infect VBN cord-007264-r1w9a6gc 143 54 tissues tissue NNS cord-007264-r1w9a6gc 144 1 A a DT cord-007264-r1w9a6gc 144 2 simple simple JJ cord-007264-r1w9a6gc 144 3 method method NN cord-007264-r1w9a6gc 144 4 of of IN cord-007264-r1w9a6gc 144 5 estimating estimate VBG cord-007264-r1w9a6gc 144 6 fifty fifty CD cord-007264-r1w9a6gc 144 7 per per IN cord-007264-r1w9a6gc 144 8 cent cent NN cord-007264-r1w9a6gc 144 9 endpoints endpoint NNS cord-007264-r1w9a6gc 144 10 Defective defective JJ cord-007264-r1w9a6gc 144 11 monocyte monocyte NNP cord-007264-r1w9a6gc 144 12 chemotactic chemotactic JJ cord-007264-r1w9a6gc 144 13 responses response NNS cord-007264-r1w9a6gc 144 14 in in IN cord-007264-r1w9a6gc 144 15 diabetes diabetes NN cord-007264-r1w9a6gc 144 16 mellitus mellitus NN cord-007264-r1w9a6gc 145 1 The the DT cord-007264-r1w9a6gc 145 2 local local JJ cord-007264-r1w9a6gc 145 3 origin origin NN cord-007264-r1w9a6gc 145 4 of of IN cord-007264-r1w9a6gc 145 5 the the DT cord-007264-r1w9a6gc 145 6 febrile febrile JJ cord-007264-r1w9a6gc 145 7 response response NN cord-007264-r1w9a6gc 145 8 induced induce VBN cord-007264-r1w9a6gc 145 9 in in IN cord-007264-r1w9a6gc 145 10 ferrets ferret NNS cord-007264-r1w9a6gc 145 11 during during IN cord-007264-r1w9a6gc 145 12 respiratory respiratory JJ cord-007264-r1w9a6gc 145 13 infection infection NN cord-007264-r1w9a6gc 145 14 with with IN cord-007264-r1w9a6gc 145 15 a a DT cord-007264-r1w9a6gc 145 16 virulent virulent JJ cord-007264-r1w9a6gc 145 17 influenza influenza NN cord-007264-r1w9a6gc 145 18 virus virus NN cord-007264-r1w9a6gc 145 19 Activation activation NN cord-007264-r1w9a6gc 145 20 of of IN cord-007264-r1w9a6gc 145 21 oxidative oxidative JJ cord-007264-r1w9a6gc 145 22 and and CC cord-007264-r1w9a6gc 145 23 arachidonic arachidonic JJ cord-007264-r1w9a6gc 145 24 acid acid JJ cord-007264-r1w9a6gc 145 25 metabolism metabolism NN cord-007264-r1w9a6gc 145 26 in in IN cord-007264-r1w9a6gc 145 27 neutrophils neutrophil NNS cord-007264-r1w9a6gc 145 28 by by IN cord-007264-r1w9a6gc 145 29 respiratory respiratory JJ cord-007264-r1w9a6gc 145 30 syncytial syncytial JJ cord-007264-r1w9a6gc 145 31 virus virus NN cord-007264-r1w9a6gc 145 32 antibody antibody NN cord-007264-r1w9a6gc 145 33 complexes complex NNS cord-007264-r1w9a6gc 145 34 : : : cord-007264-r1w9a6gc 145 35 possible possible JJ cord-007264-r1w9a6gc 145 36 role role NN cord-007264-r1w9a6gc 145 37 in in IN cord-007264-r1w9a6gc 145 38 disease disease NN cord-007264-r1w9a6gc 145 39 Atraumatic Atraumatic NNP cord-007264-r1w9a6gc 145 40 nasal nasal NN cord-007264-r1w9a6gc 145 41 biopsy biopsy NN cord-007264-r1w9a6gc 145 42 for for IN cord-007264-r1w9a6gc 145 43 studies study NNS cord-007264-r1w9a6gc 145 44 of of IN cord-007264-r1w9a6gc 145 45 respiratory respiratory JJ cord-007264-r1w9a6gc 145 46 virus virus NN cord-007264-r1w9a6gc 145 47 infection infection NN cord-007264-r1w9a6gc 145 48 in in IN cord-007264-r1w9a6gc 145 49 volunteers volunteer NNS