id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-291486-5h96msv1	Kistler, Amy	Pan-Viral Screening of Respiratory Tract Infections in Adults With and Without Asthma Reveals Unexpected Human Coronavirus and Human Rhinovirus Diversity	2007-09-15		.txt	text/plain	4476	211	45	The Virochip can detect both known and novel variants of viral pathogens present in RTIs. Given the diversity detected here, larger-scale studies will be necessary to determine whether particular substrains of viruses confer an elevated risk of asthma exacerbation. Each NatURI specimen was analyzed independently in a blinded manner by 3 distinct viral detection methods: Virochip analysis and culture isolation for 9 common respiratory pathogens (HRV; RSV; influenza viruses A and B; human parainfluenza viruses 1, 2, and 3; adenovirus; and human enterovirus) and PCR for HRV. This diversity indicates that future studies that seek to link a particular virus or set of viruses to a discrete clinical outcome, such as exacerbation of asthma symptoms, will need to include large numbers of subjects and use pan-viral detection methods (such as the Virochip) that can differentiate among such isolates.	./cache/cord-291486-5h96msv1.txt	./txt/cord-291486-5h96msv1.txt