id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-289255-qwzg7prx	Seligman, Stephen J.	Evidence for Quasi Species in Severe Acute Respiratory Syndrome-associated Coronavirus Deletion Mutants	2007-02-15		.txt	text/plain	642	43	55	title: Evidence for Quasi Species in Severe Acute Respiratory Syndrome-associated Coronavirus Deletion Mutants have reported data on a 386-nt deletion in severe acute respiratory syndrome-associated coronavirus (SARS-CoV) [1] . Because 1 patient had both the L386del variant and the wild-type variant in the same specimen, they raised the possibility that SARS-CoV exists as a quasi species, at least in some patients. Previous authors studying single-nucleotide variants from Beijing-area isolates in 2003 [2] and from the Singapore 2004 outbreak [3] have also found multiple viral sequences in the same sample that they attributed to quasi species. Although these 3 studies clearly establish the presence of a diversity of SARS-CoV genomes in individual patients, the issue of whether SARS-CoV quasi species exists remains open, particularly with respect to the 386-nt deletion. The large 386-nt deletion in SARS-associated coronavirus: evidence for quasispecies? SARS-associated coronavirus quasispecies in individual patients	./cache/cord-289255-qwzg7prx.txt	./txt/cord-289255-qwzg7prx.txt