id author title date pages extension mime words sentences flesch summary cache txt cord-288485-m3g88fl2 Lam, Katherine W Continued In-Hospital Angiotensin-Converting Enzyme Inhibitor and Angiotensin II Receptor Blocker Use in Hypertensive COVID-19 Patients Is Associated With Positive Clinical Outcome 2020-07-23 .txt text/plain 3717 185 43 title: Continued In-Hospital Angiotensin-Converting Enzyme Inhibitor and Angiotensin II Receptor Blocker Use in Hypertensive COVID-19 Patients Is Associated With Positive Clinical Outcome BACKGROUND: This study investigated continued and discontinued use of angiotensin-converting enzyme inhibitors (ACEi) or angiotensin II receptor blockers (ARB) during hospitalization of 614 hypertensive laboratory-confirmed COVID-19 patients. Because the widely used antihypertensive medications angiotensin-converting enzyme inhibitors (ACEi) and angiotensin II receptor blockers (ARB) may upregulate ACE2 receptors [7] [8] [9] , through which severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enters the host cells [10] , concerns have been raised as to whether their use may result in increased morbidity and mortality [4, [11] [12] [13] . The goal of this study was to investigate the effects of in-hospital continuation and discontinuation of ACEi/ARBs on the clinical outcomes of hypertensive COVID-19 patients, controlling for newly developed hypotension or AKI during hospitalization. ./cache/cord-288485-m3g88fl2.txt ./txt/cord-288485-m3g88fl2.txt