id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-279311-msh9wvsh	Wang, Fan	Characteristics of Peripheral Lymphocyte Subset Alteration in COVID-19 Pneumonia	2020-03-30		.txt	text/plain	2722	183	52	METHODS: The levels of peripheral lymphocyte subsets were measured by flow cytometry in 60 hospitalized COVID-19 patients before and after treatment, and their association with clinical characteristics and treatment efficacy was analyzed. In this study, we aimed to clarify the characteristics and clinical significance of peripheral lymphocyte subset alteration in COVID-19, which might help elucidate the pathogenesis and develop novel biomarkers and therapeutic strategies for COVID-19. In multivariate analysis, posttreatment decrease in CD8 + T cells (P = .011) and B cells (P = .010) and increase in CD4 + / CD8 + ratio (P = .032) indicated a poor efficacy when considering the factors of age, sex, disease severity on admission, oxygen inhalation, antiviral treatment, and use of corticosteroid and immune enhancer ( Table 2) . Effects of severe acute respiratory syndrome (SARS) coronavirus infection on peripheral blood lymphocytes and their subsets	./cache/cord-279311-msh9wvsh.txt	./txt/cord-279311-msh9wvsh.txt