id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-276005-ifn88mjd	da Silva Filho, Luiz Vicente Ribeiro Ferreira	The Differential Clinical Impact of Human Coronavirus Species in Children With Cystic Fibrosis	2012-08-01		.txt	text/plain	2485	113	42	We investigated the clinical impact of human coronaviruses (HCoV) OC43, 229E, HKU1 and NL63 in pediatric patients with cystic fibrosis (CF) during routine and exacerbation visits. The proportion of cases with acute respiratory exacerbation among patients infected with different HCoV species was compared by χ 2 or Fisher exact tests. The identification of new species of HCoV [7, 8] and the emergence of SARS HCoV [6] highlighted the potential role of these viruses as causative agents of severe lower respiratory tract infections. However, most of the studies on the clinical impact of different HCoV species were only performed among children who were hospitalized for acute respiratory tract infections, with small sample sizes and short periods of sample collection [10] . New human coronavirus, HCoV-NL63, associated with severe lower respiratory tract disease in Australia	./cache/cord-276005-ifn88mjd.txt	./txt/cord-276005-ifn88mjd.txt