id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-007264-r1w9a6gc	Turner, Ronald B.	Rhinovirus Infection of Human Embryonic Lung Fibroblasts Induces the Production of a Chemoattractant for Polymorphonuclear Leukocytes	1988-02-17		.txt	text/plain	2728	154	50	This study describes a chemoattractant for PMNLs that is elaborated by human embryonic lung fibroblast cells infected with rhinovirus. Chemotaxis assays were done in a 48-well microchemotaxis chamber with normal adult PMNLs. Medium supernatants from rhinovirus-infected cellculture attracted 87 ± 6 (mean ± SE) PMNLs/10 high-power fields (×450) compared with 38 ± 6 PMNLs/10 highpower fields attracted by medium from uninfected cell cultures (P < .0001). Human embryonic lung fibroblast cellsinfected with rhinovirus produced a chemoattractant for PMNLs. Media from R39-infected and uninfected cells attracted 87 ± 6 (mean ± SE) and 38 ± 6 PMNLs/ 10 hpf, respectively (P = .0001). Similarly, medium from uninfected cells disrupted by freezing and thawing attracted a mean of 6 ± 1 PMNLs/lO hpf (P < .0001 compared with Discussion These experiments indicate that attachment of rhinovirus to human embryonic lung fibroblast cells results in the elaboration of a chemoattractant for human PMNLs. This chemoattractant activity is not dependent upon the presence of complement.	./cache/cord-007264-r1w9a6gc.txt	./txt/cord-007264-r1w9a6gc.txt