id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-007026-ejv0gidp	Coleman, Kristen K	Adenoviral Infections in Singapore: Should New Antiviral Therapies and Vaccines Be Adopted?	2020-02-15		.txt	text/plain	4597	231	45	METHODS: To understand the epidemiology of HAdV infections in Singapore, we studied 533 HAdV-positive clinical samples collected from 396 pediatric and 137 adult patients in Singapore from 2012 to 2018. CONCLUSIONS: Singapore would benefit from more frequent studies of clinical HAdV genotypes to identify patients at risk for severe disease and help guide the use of new antiviral therapies, such as brincidofovir, and potential administration of HAdV 4 and 7 vaccine. Clinical samples previously collected from HAdV-positive patients admitted to Singapore General Hospital (SGH) and KK Women's and Children's Hospital (KKH) between 2012 and 2015 were preserved at −80°C and transferred to Duke-NUS Laboratory of One Health Research for study. Human adenovirus-C datasets consisted of 4 novel genomes from Singapore and 22 representative virus isolates from different genotypes (HAdV-C1, HAdV-C2, HAdV-C5, and HAdV-C6).	./cache/cord-007026-ejv0gidp.txt	./txt/cord-007026-ejv0gidp.txt