id author title date pages extension mime words sentences flesch summary cache txt cord-308852-qdn04pun Lei, Hao Household transmission of COVID-19-a systematic review and meta-analysis 2020-08-25 .txt text/plain 1073 79 65 title: Household transmission of COVID-19-a systematic review and meta-analysis • SARS-CoV-2 is much more transmissible than SARS-CoV and Middle East Respiratory Syndrome Coronavirus in households, which challenges the home isolation of COVID-19 patients. Here, we report a systematic review of household transmission studies of and try to assess the secondary attack rate of household COVID-19 transmission. Studies containing data on household transmission of COVID-19 were retrieved from the electronic databases: PubMed, Embase, and a Chinese database, China National Knowledge Infrastructure (CNKI) on 1 July, 2020. Case reports with only one family involved were also excluded for analysis, because the household transmissions event collection was biased towards infection caused more serious illness. Household secondary attack rate (SAR) was calculated as the number of identified cases divided by the number of household contacts. Household SAR were greater than SAR by other contacts (OR=10.72, 95% CI: 5.70-20.17, p<0.001), suggesting much higher rates of intra-family transmission of COVID-19. ./cache/cord-308852-qdn04pun.txt ./txt/cord-308852-qdn04pun.txt