id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-030594-xhp8kin0	nan	Dear the Editor,	2020-08-19		.txt	text/plain	854	61	47	have written to this journal regarding elevated admission levels of markers of liver injury (alanine aminotransferase and aspartate aminotransferase, gamma-glutamyltransferase, alkaline phosphatase and total bilirubin) may be associated with progression to severe disease or death in COVID-19. In critically ill patients with favorable outcome, cholinesterase, lymphocytes, albumin, and PaO 2 /FiO 2 ratio decreased but C-reactive protein increased toward the peak of inflammation. Later, C-reactive protein decreased with improvement in inflammation, but there was a tendency for cholinesterase, lymphocytes, albumin, and PaO 2 /FiO 2 ratio to increase. In contrast, in the severely ill patient who died, C-reactive protein poorly decreased, and cholinesterase, lymphocytes, albumin, and PaO 2 /FiO 2 ratio were not elevated. [4] Our study suggests that cholinesterase, which responds similar to the "negative" acute-phase proteins in response to inflammation, is reduced even in the acute phase of severe COVID-19 pneumonia.	./cache/cord-030594-xhp8kin0.txt	./txt/cord-030594-xhp8kin0.txt