id author title date pages extension mime words sentences flesch summary cache txt cord-306352-agppehpz Christensen, Daniel Mølager Charlson Comorbidity Index Score and Risk of Severe Outcome and Death in Danish COVID-19 Patients 2020-06-24 .txt text/plain 634 36 57 title: Charlson Comorbidity Index Score and Risk of Severe Outcome and Death in Danish COVID-19 Patients Studies assessing the impact of total comorbidity burden on outcomes of COVID-19 in age-and sex-controlled analyses are lacking. 1 In this nationwide study of Danish COVID-19 patients, we investigated if Charlson Comorbidity Index Score (CCIS) was associated with the risk of severe outcome and death. The models were used to estimate the absolute risk of both outcomes according to CCIS groups across ages 40-85 for both sexes. The estimated absolute risks of severe COVID-19 and death were increased for CCIS 1-2, 3-4, and > 4 compared with those for CCIS 0 across ages and sexes (Fig. 1) . A Charlson Comorbidity Index Score above 0 was associated with an increased risk of severe COVID-19 and death when controlled for age and sex. Figure 1 Estimated risks of severe outcome and death according to sex, age, and Charlson Comorbidity Index Score (CCIS). ./cache/cord-306352-agppehpz.txt ./txt/cord-306352-agppehpz.txt