id author title date pages extension mime words sentences flesch summary cache txt cord-349921-v1tewoi0 Giorgi Rossi, Paolo Case fatality rate in patients with COVID-19 infection and its relationship with length of follow up() 2020-05-05 .txt text/plain 655 40 58 title: Case fatality rate in patients with COVID-19 infection and its relationship with length of follow up() In their systematic review on the clinical characteristics of COVID-19, Wu and colleagues report a 3.2% case fatality rate (CFR), ranging from 2% to 4% 1 with strong heterogeneity between studies (I 2 =100%). 2 The authors suggest that higher complication and fatality rate in Wuhan could be due to the limited clinical experience in the initial phase of the epidemic. We report data from the COVID-19 information system set up in Italy by the National Institute of Health and described elsewhere, 5,6 diagnosed from February 20 to March 29 and followed up to April 5 in Emilia-Romagna region (approximately 4.5 million inhabitants). Our data show that, according to the Italian definition of COVID-related death, 5,6 the CFR can reach about 20% if we follow up patients for a long enough time to observe the vast majority of deaths. Case-Fatality Rate and Characteristics of Patients Dying in Relation to COVID-19 in Italy ./cache/cord-349921-v1tewoi0.txt ./txt/cord-349921-v1tewoi0.txt