id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-349782-djzxkus2	van Kasteren, Puck B.	Response to letter of concern by Oladimeji and Pickford of PrimerDesign	2020-06-29		.txt	text/plain	994	47	54	On top of this, they have dedicated their time to providing the global diagnostic community with a much needed initial comparison of commercially available COVID-19 RT-PCR kits, which was recently published in the Journal of Clinical Virology (1). Obviously, our selection of 13 SARS-CoV-2-positive clinical samples does not reflect the variation encountered in the field, especially since we specifically included several samples with relatively high Ct values. Notably, the FIND initiative protocol (3) and the presented results for PrimerDesign and other kits (4) do not provide information regarding the composition of the 50 positive samples included in the study and no information on viral loads using e.g. reference Ct values. If only samples from patients in the hospital setting that have relatively high viral loads have been selected, every kit will score a near 100% diagnostic clinical sensitivity. We have specifically sought for the clinical performance using samples that have a viral load around the LOD of the kits.	./cache/cord-349782-djzxkus2.txt	./txt/cord-349782-djzxkus2.txt