id author title date pages extension mime words sentences flesch summary cache txt cord-337799-mc1oqhf4 Mak, Gannon CK Analytical sensitivity and clinical sensitivity of the three rapid antigen detection kits for detection of SARS-CoV-2 virus 2020-10-29 .txt text/plain 2329 153 60 STUDY DESIGN: Analytical sensitivity for the detection of SARS-CoV-2 virus was determined by limit of detection (LOD) using PCR as a reference method. Clinical sensitivity of RAD kits ranged from 22.9% to 71.4% for detecting specimens from COVID-19 patients. CONCLUSIONS: Although RAD kits were less sensitive than RT-PCR, understanding the clinical characteristics of different RAD kits can guide us to obtain suitable specimens for testing. Besides RT-PCR, rapid antigen detection (RAD) kits for qualitative determination of SARS-CoV-2 antigen are available. The purpose of this evaluation is to assess analytical sensitivity of the three SARS-CoV-2 RAD kits by means of limit of detection (LOD) using a set of serial tenfold dilution samples; and It means that if we set a cut off by means of ≤day X after symptom onset for performing RAD kits, we will miss another group of specimens having a similar high viral load. ./cache/cord-337799-mc1oqhf4.txt ./txt/cord-337799-mc1oqhf4.txt