id author title date pages extension mime words sentences flesch summary cache txt cord-328290-kbysppgb Beckmann, Christiane Diagnostic performance of near-patient testing for influenza 2015-03-31 .txt text/plain 1984 145 55 Community-acquired respiratory virus Isothermal PCR Turn-around time (TAT) Antigen detection Nucleic acid amplification testing (NAT) a b s t r a c t Background: Rapid diagnosis of influenza is important for controlling outbreaks and starting antiviral therapy. Objectives: To evaluate the performance of a rapid isothermal NAT and two DADs. Study design: During February-May 2014, we tested 211 consecutive patients with influenza-like illness using a commercial isothermal NAT (Alere TM Influenza A&B) as well as the DAD Sofia ® Influenza A + B and BinaxNOW ® Influenza A&B for detection of influenza-A and -B virus. Results: Compared to RespiFinder-22 ® , the isothermal NAT Alere TM Influenza A&B, and the DAD Sofia ® Influenza A + B and BinaxNOW ® Influenza A&B had sensitivities of 77.8%, 59.3% and 29.6%, and specificities of 99.5%, 98.9% and 100%, respectively, for the first 211 patient samples. ./cache/cord-328290-kbysppgb.txt ./txt/cord-328290-kbysppgb.txt