id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-295957-s17z2ccf	Bordi, Licia	Rapid and sensitive detection of SARS-CoV-2 RNA using the Simplexa™ COVID-19 direct assay	2020-05-04		.txt	text/plain	1923	108	52	BACKGROUND: So far, one of the major drawbacks of the available molecular assays for the diagnosis of severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) is the need for viral nucleic acid extraction from clinical specimens. CONCLUSIONS: The high sensitivity and specificity of this new assay indicate that it is promising for laboratory diagnosis, enabling highspeed detection in just over one hour, which is significantly faster than the up to five hours currently required by traditional extraction followed by amplification technologies, thus allowing prompt decision making regarding isolation of infected patients. Moreover, to evaluate the performance of the test in a different clinical specimen, a total of 33 Broncho-Alveolar Lavage (BAL) collected for COVID-19 diagnosis between 20 March and 03 April 2020 were also analysed in parallel with the Simplexa™ COVID-19 Direct assay and the routine laboratory method, based on the WHO protocols (7, 8) , using the Abbot m2000 extraction platform.	./cache/cord-295957-s17z2ccf.txt	./txt/cord-295957-s17z2ccf.txt