id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-295600-xe3ruu9a	Calarota, Sandra A.	T-lymphocyte subsets in lung transplant recipients: association between nadir CD4 T-cell count and viral infections after transplantation	2015-06-17		.txt	text/plain	3588	173	50	OBJECTIVES: To analyze the kinetics of T-lymphocyte subsets in LTR and the association between nadir CD4 T-cell count and viral infections after transplantation. STUDY DESIGN: Serial measurements of peripheral blood CD4 and CD8 T-cell counts obtained during the first year post-transplantation from 83 consecutive LTR and their correlation with both viral OI and community-acquired infections post-transplantation were retrospectively analyzed. To analyze the kinetics of CD4 and CD8 T-cell counts in peripheral blood obtained from LTR during the first year after transplantation and evaluated the association between nadir CD4 T-cell count with the development of viral infections posttransplantation. The present study provides a detailed analysis of T-cell subsets in peripheral blood during the first 12 months after lung transplantation and correlates these immunological data with infectious complications. Although the study has limitations, our findings reveal an association between nadir CD4 T-cell count and incidence of infectious episodes in LTR, suggesting that, particularly in patients with low CD4 T-cell numbers, monitoring of infections should be intensified to improve early detection and treatment.	./cache/cord-295600-xe3ruu9a.txt	./txt/cord-295600-xe3ruu9a.txt