id author title date pages extension mime words sentences flesch summary cache txt cord-273783-z71bquck Dijkman, Ronald The dominance of human coronavirus OC43 and NL63 infections in infants 2011-12-19 .txt text/plain 3068 174 54 The frequencies of severe HCoVs infection was determined by real time RT-PCR among 1471 hospitalized infants (<2-years old) with acute respiratory tract disease. In addition the chain of seroconversions will reveal whether immunity to one HCoV may protect against infection by one of the other HCoVs. Two distinct study groups were monitored: healthy children (newborns) and children hospitalized due to respiratory disease. Samples in this study were selected from the complete set based on the following criteria: children who were hospitalized with acute respiratory tract illness and below the age of 2 years. The characteristic frequency of infection, in the order HCoV-OC43 ≥ HCoV-NL63 > HCoV-HKU1 ≥ HCoV-229E, observed via seroconversion but also by direct detection of the virus in hospitalized children over multiple years is in contrast with some previous studies. ./cache/cord-273783-z71bquck.txt ./txt/cord-273783-z71bquck.txt