id author title date pages extension mime words sentences flesch summary cache txt cord-268830-8li6xhbu Kozak, Robert Severity of coronavirus respiratory tract infections in adults admitted to acute care in Toronto, Ontario 2020-03-29 .txt text/plain 3130 160 44 It has been reported that immunocompromised patients, particularly hematopoietic cell transplant recipients, are at increased risk of lower respiratory tract infections, prolonged viral shedding and mortality, often comparable to what is seen with influenza virus [3, 4] . In acute care hospitals, much of the focus in diagnostics has been placed on influenza and respiratory syncytial virus (RSV) because of the severe infection and poor outcomes of hospitalized patients, yet the burden of CoV in acute care is not well studied. The primary objective of this study was to describe the burden of CoV among patients admitted to an acute care hospital in Toronto, Canada over a six-year period, and identify the predictors of severe disease. In our cohort smoking predicted ICU admission and/or mortality, which is similar to what was reported in a prior study on patients infected with HKU1 CoV [18] The impact of gender on outcomes of CoV, as determined by our multivariate analysis is in contrast with what is reported for MERS CoV. ./cache/cord-268830-8li6xhbu.txt ./txt/cord-268830-8li6xhbu.txt