id author title date pages extension mime words sentences flesch summary cache txt cord-263389-m6x9gxwe AlGhounaim, M. Diagnostic yield and clinical impact of routine cell culture for respiratory viruses among children with a negative multiplex RT-PCR result 2017-07-29 .txt text/plain 1929 113 41 title: Diagnostic yield and clinical impact of routine cell culture for respiratory viruses among children with a negative multiplex RT-PCR result Respiratory samples from hospitalized or immunocompromised patients <18 years old were routinely inoculated on traditional tube cell culture monolayers if they tested negative by a PCR assay for 12 respiratory viruses. Still, some authors suggest performing viral culture in a backup role in respiratory specimens from high-risk populations to detect viruses that are not part of the RT-PCR assay or whose genomes have mutations that may lead to false-negative RT-PCR results [5, 6] . We performed a single-center retrospective cohort study at the Montreal Children' population included all patients < 18 years old with a viral culture performed on a respiratory specimen that had tested negative by multiplex PCR. However, in our clinical laboratory, routine viral cultures from PCR-negative respiratory specimens had minimal impact on patient care. ./cache/cord-263389-m6x9gxwe.txt ./txt/cord-263389-m6x9gxwe.txt