id sid tid token lemma pos cord-310304-f28tjmi8 1 1 key key NN cord-310304-f28tjmi8 1 2 : : : cord-310304-f28tjmi8 2 1 cord-310304-f28tjmi8 cord-310304-f28tjmi8 NNP cord-310304-f28tjmi8 2 2 authors author NNS cord-310304-f28tjmi8 2 3 : : : cord-310304-f28tjmi8 2 4 Alcendor Alcendor NNP cord-310304-f28tjmi8 2 5 , , , cord-310304-f28tjmi8 2 6 Donald Donald NNP cord-310304-f28tjmi8 2 7 J. J. NNP cord-310304-f28tjmi8 2 8 title title NN cord-310304-f28tjmi8 2 9 : : : cord-310304-f28tjmi8 3 1 Racial racial JJ cord-310304-f28tjmi8 3 2 Disparities disparity NNS cord-310304-f28tjmi8 4 1 -Associated -Associated NNP cord-310304-f28tjmi8 4 2 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 4 3 Mortality Mortality NNP cord-310304-f28tjmi8 4 4 among among IN cord-310304-f28tjmi8 4 5 Minority Minority NNP cord-310304-f28tjmi8 4 6 Populations Populations NNPS cord-310304-f28tjmi8 4 7 in in IN cord-310304-f28tjmi8 4 8 the the DT cord-310304-f28tjmi8 4 9 US US NNP cord-310304-f28tjmi8 4 10 date date NN cord-310304-f28tjmi8 4 11 : : : cord-310304-f28tjmi8 4 12 2020 2020 CD cord-310304-f28tjmi8 4 13 - - HYPH cord-310304-f28tjmi8 4 14 07 07 CD cord-310304-f28tjmi8 4 15 - - SYM cord-310304-f28tjmi8 4 16 30 30 CD cord-310304-f28tjmi8 4 17 journal journal NN cord-310304-f28tjmi8 4 18 : : : cord-310304-f28tjmi8 4 19 J J NNP cord-310304-f28tjmi8 4 20 Clin Clin NNP cord-310304-f28tjmi8 4 21 Med Med NNP cord-310304-f28tjmi8 4 22 DOI doi NN cord-310304-f28tjmi8 4 23 : : : cord-310304-f28tjmi8 5 1 10.3390 10.3390 CD cord-310304-f28tjmi8 5 2 / / SYM cord-310304-f28tjmi8 5 3 jcm9082442 jcm9082442 NNP cord-310304-f28tjmi8 5 4 sha sha NNP cord-310304-f28tjmi8 5 5 : : : cord-310304-f28tjmi8 5 6 0d653bc996769e1e93bb875811e970ba37a9d1d3 0d653bc996769e1e93bb875811e970ba37a9d1d3 CD cord-310304-f28tjmi8 6 1 doc_id doc_id CD cord-310304-f28tjmi8 6 2 : : : cord-310304-f28tjmi8 6 3 310304 310304 CD cord-310304-f28tjmi8 6 4 cord_uid cord_uid NN cord-310304-f28tjmi8 6 5 : : : cord-310304-f28tjmi8 7 1 f28tjmi8 f28tjmi8 NNP cord-310304-f28tjmi8 8 1 Severe severe JJ cord-310304-f28tjmi8 8 2 acute acute JJ cord-310304-f28tjmi8 8 3 respiratory respiratory JJ cord-310304-f28tjmi8 8 4 syndrome syndrome NN cord-310304-f28tjmi8 8 5 coronavirus coronavirus NN cord-310304-f28tjmi8 8 6 2 2 CD cord-310304-f28tjmi8 9 1 ( ( -LRB- cord-310304-f28tjmi8 9 2 SARS SARS NNP cord-310304-f28tjmi8 9 3 - - HYPH cord-310304-f28tjmi8 9 4 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 9 5 ) ) -RRB- cord-310304-f28tjmi8 9 6 , , , cord-310304-f28tjmi8 9 7 a a DT cord-310304-f28tjmi8 9 8 betacoronavirus betacoronavirus NN cord-310304-f28tjmi8 9 9 that that WDT cord-310304-f28tjmi8 9 10 causes cause VBZ cord-310304-f28tjmi8 9 11 the the DT cord-310304-f28tjmi8 9 12 novel novel JJ cord-310304-f28tjmi8 9 13 coronavirus coronavirus NN cord-310304-f28tjmi8 9 14 disease disease NN cord-310304-f28tjmi8 9 15 2019 2019 CD cord-310304-f28tjmi8 9 16 ( ( -LRB- cord-310304-f28tjmi8 9 17 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 9 18 ) ) -RRB- cord-310304-f28tjmi8 9 19 , , , cord-310304-f28tjmi8 9 20 is be VBZ cord-310304-f28tjmi8 9 21 highly highly RB cord-310304-f28tjmi8 9 22 transmissible transmissible JJ cord-310304-f28tjmi8 9 23 and and CC cord-310304-f28tjmi8 9 24 pathogenic pathogenic JJ cord-310304-f28tjmi8 9 25 for for IN cord-310304-f28tjmi8 9 26 humans human NNS cord-310304-f28tjmi8 9 27 and and CC cord-310304-f28tjmi8 9 28 may may MD cord-310304-f28tjmi8 9 29 cause cause VB cord-310304-f28tjmi8 9 30 life life NN cord-310304-f28tjmi8 9 31 - - HYPH cord-310304-f28tjmi8 9 32 threatening threaten VBG cord-310304-f28tjmi8 9 33 disease disease NN cord-310304-f28tjmi8 9 34 and and CC cord-310304-f28tjmi8 9 35 mortality mortality NN cord-310304-f28tjmi8 9 36 , , , cord-310304-f28tjmi8 9 37 especially especially RB cord-310304-f28tjmi8 9 38 in in IN cord-310304-f28tjmi8 9 39 individuals individual NNS cord-310304-f28tjmi8 9 40 with with IN cord-310304-f28tjmi8 9 41 underlying underlying JJ cord-310304-f28tjmi8 9 42 comorbidities comorbiditie NNS cord-310304-f28tjmi8 9 43 . . . cord-310304-f28tjmi8 10 1 First first RB cord-310304-f28tjmi8 10 2 identified identify VBN cord-310304-f28tjmi8 10 3 in in IN cord-310304-f28tjmi8 10 4 an an DT cord-310304-f28tjmi8 10 5 outbreak outbreak NN cord-310304-f28tjmi8 10 6 in in IN cord-310304-f28tjmi8 10 7 Wuhan Wuhan NNP cord-310304-f28tjmi8 10 8 , , , cord-310304-f28tjmi8 10 9 China China NNP cord-310304-f28tjmi8 10 10 , , , cord-310304-f28tjmi8 10 11 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 10 12 is be VBZ cord-310304-f28tjmi8 10 13 affecting affect VBG cord-310304-f28tjmi8 10 14 more more JJR cord-310304-f28tjmi8 10 15 than than IN cord-310304-f28tjmi8 10 16 185 185 CD cord-310304-f28tjmi8 10 17 countries country NNS cord-310304-f28tjmi8 10 18 and and CC cord-310304-f28tjmi8 10 19 territories territory NNS cord-310304-f28tjmi8 10 20 around around IN cord-310304-f28tjmi8 10 21 the the DT cord-310304-f28tjmi8 10 22 world world NN cord-310304-f28tjmi8 10 23 , , , cord-310304-f28tjmi8 10 24 with with IN cord-310304-f28tjmi8 10 25 more more JJR cord-310304-f28tjmi8 10 26 than than IN cord-310304-f28tjmi8 10 27 15,754,651 15,754,651 CD cord-310304-f28tjmi8 10 28 confirmed confirm VBN cord-310304-f28tjmi8 10 29 cases case NNS cord-310304-f28tjmi8 10 30 and and CC cord-310304-f28tjmi8 10 31 more more JJR cord-310304-f28tjmi8 10 32 than than IN cord-310304-f28tjmi8 10 33 640,029 640,029 CD cord-310304-f28tjmi8 10 34 deaths death NNS cord-310304-f28tjmi8 10 35 . . . cord-310304-f28tjmi8 11 1 Since since IN cord-310304-f28tjmi8 11 2 December December NNP cord-310304-f28tjmi8 11 3 2019 2019 CD cord-310304-f28tjmi8 11 4 , , , cord-310304-f28tjmi8 11 5 SARS SARS NNP cord-310304-f28tjmi8 11 6 - - HYPH cord-310304-f28tjmi8 11 7 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 11 8 transmission transmission NN cord-310304-f28tjmi8 11 9 has have VBZ cord-310304-f28tjmi8 11 10 become become VBN cord-310304-f28tjmi8 11 11 a a DT cord-310304-f28tjmi8 11 12 global global JJ cord-310304-f28tjmi8 11 13 threat threat NN cord-310304-f28tjmi8 11 14 , , , cord-310304-f28tjmi8 11 15 which which WDT cord-310304-f28tjmi8 11 16 includes include VBZ cord-310304-f28tjmi8 11 17 confirmed confirm VBN cord-310304-f28tjmi8 11 18 cases case NNS cord-310304-f28tjmi8 11 19 in in IN cord-310304-f28tjmi8 11 20 all all DT cord-310304-f28tjmi8 11 21 50 50 CD cord-310304-f28tjmi8 11 22 states state NNS cord-310304-f28tjmi8 11 23 within within IN cord-310304-f28tjmi8 11 24 the the DT cord-310304-f28tjmi8 11 25 United United NNP cord-310304-f28tjmi8 11 26 States States NNP cord-310304-f28tjmi8 11 27 ( ( -LRB- cord-310304-f28tjmi8 11 28 US US NNP cord-310304-f28tjmi8 11 29 ) ) -RRB- cord-310304-f28tjmi8 11 30 . . . cord-310304-f28tjmi8 12 1 As as IN cord-310304-f28tjmi8 12 2 of of IN cord-310304-f28tjmi8 12 3 25 25 CD cord-310304-f28tjmi8 12 4 July July NNP cord-310304-f28tjmi8 12 5 2020 2020 CD cord-310304-f28tjmi8 12 6 , , , cord-310304-f28tjmi8 12 7 the the DT cord-310304-f28tjmi8 12 8 Johns Johns NNP cord-310304-f28tjmi8 12 9 Hopkins Hopkins NNP cord-310304-f28tjmi8 12 10 Whiting Whiting NNP cord-310304-f28tjmi8 12 11 School School NNP cord-310304-f28tjmi8 12 12 of of IN cord-310304-f28tjmi8 12 13 Engineering Engineering NNP cord-310304-f28tjmi8 12 14 Center Center NNP cord-310304-f28tjmi8 12 15 for for IN cord-310304-f28tjmi8 12 16 Systems Systems NNP cord-310304-f28tjmi8 12 17 Science Science NNP cord-310304-f28tjmi8 12 18 and and CC cord-310304-f28tjmi8 12 19 Engineering Engineering NNP cord-310304-f28tjmi8 12 20 reports report VBZ cord-310304-f28tjmi8 12 21 more more JJR cord-310304-f28tjmi8 12 22 than than IN cord-310304-f28tjmi8 12 23 4,112,651 4,112,651 CD cord-310304-f28tjmi8 12 24 cases case NNS cord-310304-f28tjmi8 12 25 and and CC cord-310304-f28tjmi8 12 26 145,546 145,546 CD cord-310304-f28tjmi8 12 27 deaths death NNS cord-310304-f28tjmi8 12 28 . . . cord-310304-f28tjmi8 13 1 To to IN cord-310304-f28tjmi8 13 2 date date NN cord-310304-f28tjmi8 13 3 , , , cord-310304-f28tjmi8 13 4 health health NN cord-310304-f28tjmi8 13 5 disparities disparity NNS cord-310304-f28tjmi8 13 6 are be VBP cord-310304-f28tjmi8 13 7 associated associate VBN cord-310304-f28tjmi8 13 8 with with IN cord-310304-f28tjmi8 13 9 COVID-19 covid-19 JJ cord-310304-f28tjmi8 13 10 mortality mortality NN cord-310304-f28tjmi8 13 11 among among IN cord-310304-f28tjmi8 13 12 underserved underserved JJ cord-310304-f28tjmi8 13 13 populations population NNS cord-310304-f28tjmi8 13 14 . . . cord-310304-f28tjmi8 14 1 Here here RB cord-310304-f28tjmi8 14 2 , , , cord-310304-f28tjmi8 14 3 the the DT cord-310304-f28tjmi8 14 4 author author NN cord-310304-f28tjmi8 14 5 explores explore VBZ cord-310304-f28tjmi8 14 6 potential potential JJ cord-310304-f28tjmi8 14 7 underlying underlie VBG cord-310304-f28tjmi8 14 8 reasons reason NNS cord-310304-f28tjmi8 14 9 for for IN cord-310304-f28tjmi8 14 10 reported report VBN cord-310304-f28tjmi8 14 11 disproportionate disproportionate JJ cord-310304-f28tjmi8 14 12 , , , cord-310304-f28tjmi8 14 13 increased increase VBN cord-310304-f28tjmi8 14 14 risks risk NNS cord-310304-f28tjmi8 14 15 of of IN cord-310304-f28tjmi8 14 16 mortality mortality NN cord-310304-f28tjmi8 14 17 among among IN cord-310304-f28tjmi8 14 18 African african JJ cord-310304-f28tjmi8 14 19 Americans Americans NNPS cord-310304-f28tjmi8 14 20 and and CC cord-310304-f28tjmi8 14 21 Hispanics Hispanics NNPS cord-310304-f28tjmi8 14 22 / / SYM cord-310304-f28tjmi8 14 23 Latinos Latinos NNPS cord-310304-f28tjmi8 14 24 with with IN cord-310304-f28tjmi8 14 25 COVID-19 covid-19 NN cord-310304-f28tjmi8 14 26 compared compare VBN cord-310304-f28tjmi8 14 27 with with IN cord-310304-f28tjmi8 14 28 non non JJ cord-310304-f28tjmi8 14 29 - - JJ cord-310304-f28tjmi8 14 30 Hispanic hispanic JJ cord-310304-f28tjmi8 14 31 Whites white NNS cord-310304-f28tjmi8 14 32 . . . cord-310304-f28tjmi8 15 1 The the DT cord-310304-f28tjmi8 15 2 author author NN cord-310304-f28tjmi8 15 3 examines examine VBZ cord-310304-f28tjmi8 15 4 the the DT cord-310304-f28tjmi8 15 5 underlying underlie VBG cord-310304-f28tjmi8 15 6 clinical clinical JJ cord-310304-f28tjmi8 15 7 implications implication NNS cord-310304-f28tjmi8 15 8 that that WDT cord-310304-f28tjmi8 15 9 may may MD cord-310304-f28tjmi8 15 10 predispose predispose VB cord-310304-f28tjmi8 15 11 minority minority NN cord-310304-f28tjmi8 15 12 populations population NNS cord-310304-f28tjmi8 15 13 and and CC cord-310304-f28tjmi8 15 14 the the DT cord-310304-f28tjmi8 15 15 adverse adverse JJ cord-310304-f28tjmi8 15 16 clinical clinical JJ cord-310304-f28tjmi8 15 17 outcomes outcome NNS cord-310304-f28tjmi8 15 18 that that WDT cord-310304-f28tjmi8 15 19 may may MD cord-310304-f28tjmi8 15 20 contribute contribute VB cord-310304-f28tjmi8 15 21 to to IN cord-310304-f28tjmi8 15 22 increased increase VBN cord-310304-f28tjmi8 15 23 risk risk NN cord-310304-f28tjmi8 15 24 of of IN cord-310304-f28tjmi8 15 25 mortality mortality NN cord-310304-f28tjmi8 15 26 . . . cord-310304-f28tjmi8 16 1 Government government NN cord-310304-f28tjmi8 16 2 and and CC cord-310304-f28tjmi8 16 3 community community NN cord-310304-f28tjmi8 16 4 - - HYPH cord-310304-f28tjmi8 16 5 based base VBN cord-310304-f28tjmi8 16 6 strategies strategy NNS cord-310304-f28tjmi8 16 7 to to TO cord-310304-f28tjmi8 16 8 safeguard safeguard VB cord-310304-f28tjmi8 16 9 minority minority NN cord-310304-f28tjmi8 16 10 populations population NNS cord-310304-f28tjmi8 16 11 at at IN cord-310304-f28tjmi8 16 12 risk risk NN cord-310304-f28tjmi8 16 13 for for IN cord-310304-f28tjmi8 16 14 increased increase VBN cord-310304-f28tjmi8 16 15 morbidity morbidity NN cord-310304-f28tjmi8 16 16 and and CC cord-310304-f28tjmi8 16 17 mortality mortality NN cord-310304-f28tjmi8 16 18 are be VBP cord-310304-f28tjmi8 16 19 essential essential JJ cord-310304-f28tjmi8 16 20 . . . cord-310304-f28tjmi8 17 1 Underserved underserved JJ cord-310304-f28tjmi8 17 2 populations population NNS cord-310304-f28tjmi8 17 3 living live VBG cord-310304-f28tjmi8 17 4 in in IN cord-310304-f28tjmi8 17 5 poverty poverty NN cord-310304-f28tjmi8 17 6 with with IN cord-310304-f28tjmi8 17 7 limited limited JJ cord-310304-f28tjmi8 17 8 access access NN cord-310304-f28tjmi8 17 9 to to IN cord-310304-f28tjmi8 17 10 social social JJ cord-310304-f28tjmi8 17 11 services service NNS cord-310304-f28tjmi8 17 12 across across IN cord-310304-f28tjmi8 17 13 the the DT cord-310304-f28tjmi8 17 14 US US NNP cord-310304-f28tjmi8 17 15 are be VBP cord-310304-f28tjmi8 17 16 more more RBR cord-310304-f28tjmi8 17 17 likely likely JJ cord-310304-f28tjmi8 17 18 to to TO cord-310304-f28tjmi8 17 19 have have VB cord-310304-f28tjmi8 17 20 underlying underlying JJ cord-310304-f28tjmi8 17 21 medical medical JJ cord-310304-f28tjmi8 17 22 conditions condition NNS cord-310304-f28tjmi8 17 23 and and CC cord-310304-f28tjmi8 17 24 are be VBP cord-310304-f28tjmi8 17 25 among among IN cord-310304-f28tjmi8 17 26 the the DT cord-310304-f28tjmi8 17 27 most most RBS cord-310304-f28tjmi8 17 28 vulnerable vulnerable JJ cord-310304-f28tjmi8 17 29 . . . cord-310304-f28tjmi8 18 1 Societal societal JJ cord-310304-f28tjmi8 18 2 and and CC cord-310304-f28tjmi8 18 3 cultural cultural JJ cord-310304-f28tjmi8 18 4 barriers barrier NNS cord-310304-f28tjmi8 18 5 for for IN cord-310304-f28tjmi8 18 6 ethnic ethnic JJ cord-310304-f28tjmi8 18 7 minorities minority NNS cord-310304-f28tjmi8 18 8 to to TO cord-310304-f28tjmi8 18 9 achieve achieve VB cord-310304-f28tjmi8 18 10 health health NN cord-310304-f28tjmi8 18 11 equity equity NN cord-310304-f28tjmi8 18 12 are be VBP cord-310304-f28tjmi8 18 13 systemic systemic JJ cord-310304-f28tjmi8 18 14 issues issue NNS cord-310304-f28tjmi8 18 15 that that WDT cord-310304-f28tjmi8 18 16 may may MD cord-310304-f28tjmi8 18 17 be be VB cord-310304-f28tjmi8 18 18 addressed address VBN cord-310304-f28tjmi8 18 19 only only RB cord-310304-f28tjmi8 18 20 through through IN cord-310304-f28tjmi8 18 21 shifts shift NNS cord-310304-f28tjmi8 18 22 in in IN cord-310304-f28tjmi8 18 23 governmental governmental JJ cord-310304-f28tjmi8 18 24 policies policy NNS cord-310304-f28tjmi8 18 25 , , , cord-310304-f28tjmi8 18 26 producing produce VBG cord-310304-f28tjmi8 18 27 long long JJ cord-310304-f28tjmi8 18 28 - - HYPH cord-310304-f28tjmi8 18 29 overdue overdue JJ cord-310304-f28tjmi8 18 30 , , , cord-310304-f28tjmi8 18 31 substantive substantive JJ cord-310304-f28tjmi8 18 32 changes change NNS cord-310304-f28tjmi8 18 33 to to TO cord-310304-f28tjmi8 18 34 end end VB cord-310304-f28tjmi8 18 35 health health NN cord-310304-f28tjmi8 18 36 care care NN cord-310304-f28tjmi8 18 37 inequities inequity NNS cord-310304-f28tjmi8 18 38 . . . cord-310304-f28tjmi8 19 1 Coronavirus Coronavirus NNP cord-310304-f28tjmi8 19 2 disease disease NN cord-310304-f28tjmi8 19 3 2019 2019 CD cord-310304-f28tjmi8 19 4 is be VBZ cord-310304-f28tjmi8 19 5 caused cause VBN cord-310304-f28tjmi8 19 6 by by IN cord-310304-f28tjmi8 19 7 the the DT cord-310304-f28tjmi8 19 8 severe severe JJ cord-310304-f28tjmi8 19 9 acute acute JJ cord-310304-f28tjmi8 19 10 respiratory respiratory JJ cord-310304-f28tjmi8 19 11 syndrome syndrome NN cord-310304-f28tjmi8 19 12 coronavirus coronavirus NN cord-310304-f28tjmi8 19 13 2 2 CD cord-310304-f28tjmi8 20 1 ( ( -LRB- cord-310304-f28tjmi8 20 2 SARS SARS NNP cord-310304-f28tjmi8 20 3 - - HYPH cord-310304-f28tjmi8 20 4 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 20 5 ) ) -RRB- cord-310304-f28tjmi8 21 1 [ [ -LRB- cord-310304-f28tjmi8 21 2 1 1 CD cord-310304-f28tjmi8 21 3 ] ] -RRB- cord-310304-f28tjmi8 21 4 [ [ -LRB- cord-310304-f28tjmi8 21 5 2 2 CD cord-310304-f28tjmi8 21 6 ] ] -RRB- cord-310304-f28tjmi8 21 7 [ [ -LRB- cord-310304-f28tjmi8 21 8 3 3 CD cord-310304-f28tjmi8 21 9 ] ] -RRB- cord-310304-f28tjmi8 21 10 [ [ -LRB- cord-310304-f28tjmi8 21 11 4 4 CD cord-310304-f28tjmi8 21 12 ] ] -RRB- cord-310304-f28tjmi8 21 13 . . . cord-310304-f28tjmi8 22 1 To to IN cord-310304-f28tjmi8 22 2 date date NN cord-310304-f28tjmi8 22 3 , , , cord-310304-f28tjmi8 22 4 seven seven CD cord-310304-f28tjmi8 22 5 human human JJ cord-310304-f28tjmi8 22 6 coronaviruses coronaviruse NNS cord-310304-f28tjmi8 22 7 ( ( -LRB- cord-310304-f28tjmi8 22 8 HCoVs HCoVs NNP cord-310304-f28tjmi8 22 9 ) ) -RRB- cord-310304-f28tjmi8 22 10 have have VBP cord-310304-f28tjmi8 22 11 been be VBN cord-310304-f28tjmi8 22 12 identified identify VBN cord-310304-f28tjmi8 22 13 , , , cord-310304-f28tjmi8 22 14 including include VBG cord-310304-f28tjmi8 22 15 two two CD cord-310304-f28tjmi8 22 16 α α NN cord-310304-f28tjmi8 22 17 - - HYPH cord-310304-f28tjmi8 22 18 CoVs CoVs NNP cord-310304-f28tjmi8 22 19 ( ( -LRB- cord-310304-f28tjmi8 22 20 HCoV-229E HCoV-229E NNP cord-310304-f28tjmi8 22 21 and and CC cord-310304-f28tjmi8 22 22 HCoV HCoV NNP cord-310304-f28tjmi8 22 23 - - HYPH cord-310304-f28tjmi8 22 24 NL63 NL63 NNP cord-310304-f28tjmi8 22 25 ) ) -RRB- cord-310304-f28tjmi8 22 26 and and CC cord-310304-f28tjmi8 22 27 five five CD cord-310304-f28tjmi8 22 28 Betacoronaviruses Betacoronaviruses NNP cord-310304-f28tjmi8 22 29 ( ( -LRB- cord-310304-f28tjmi8 22 30 β β NN cord-310304-f28tjmi8 22 31 - - HYPH cord-310304-f28tjmi8 22 32 CoVs CoVs NNP cord-310304-f28tjmi8 22 33 ) ) -RRB- cord-310304-f28tjmi8 22 34 ( ( -LRB- cord-310304-f28tjmi8 22 35 HCoV HCoV NNP cord-310304-f28tjmi8 22 36 - - HYPH cord-310304-f28tjmi8 22 37 OC43 OC43 NNP cord-310304-f28tjmi8 22 38 , , , cord-310304-f28tjmi8 22 39 HCoV HCoV NNP cord-310304-f28tjmi8 22 40 - - HYPH cord-310304-f28tjmi8 22 41 HKU1 HKU1 NNP cord-310304-f28tjmi8 22 42 , , , cord-310304-f28tjmi8 22 43 severe severe JJ cord-310304-f28tjmi8 22 44 acute acute JJ cord-310304-f28tjmi8 22 45 respiratory respiratory JJ cord-310304-f28tjmi8 22 46 syndrome syndrome NN cord-310304-f28tjmi8 22 47 CoV cov NN cord-310304-f28tjmi8 22 48 [ [ -LRB- cord-310304-f28tjmi8 22 49 SARS SARS NNP cord-310304-f28tjmi8 22 50 - - HYPH cord-310304-f28tjmi8 22 51 CoV CoV NNP cord-310304-f28tjmi8 22 52 ] ] -RRB- cord-310304-f28tjmi8 22 53 , , , cord-310304-f28tjmi8 22 54 Middle Middle NNP cord-310304-f28tjmi8 22 55 East East NNP cord-310304-f28tjmi8 22 56 respiratory respiratory JJ cord-310304-f28tjmi8 22 57 syndrome syndrome NN cord-310304-f28tjmi8 22 58 CoV cov NN cord-310304-f28tjmi8 22 59 [ [ -LRB- cord-310304-f28tjmi8 22 60 MERS MERS NNP cord-310304-f28tjmi8 22 61 - - HYPH cord-310304-f28tjmi8 22 62 CoV CoV NNP cord-310304-f28tjmi8 22 63 ] ] -RRB- cord-310304-f28tjmi8 22 64 , , , cord-310304-f28tjmi8 22 65 and and CC cord-310304-f28tjmi8 22 66 most most RBS cord-310304-f28tjmi8 22 67 recently recently RB cord-310304-f28tjmi8 22 68 β β NN cord-310304-f28tjmi8 22 69 - - HYPH cord-310304-f28tjmi8 22 70 CoV CoV NNP cord-310304-f28tjmi8 22 71 SARS SARS NNP cord-310304-f28tjmi8 22 72 - - HYPH cord-310304-f28tjmi8 22 73 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 22 74 ) ) -RRB- cord-310304-f28tjmi8 22 75 [ [ -LRB- cord-310304-f28tjmi8 22 76 5 5 CD cord-310304-f28tjmi8 22 77 ] ] -RRB- cord-310304-f28tjmi8 22 78 [ [ -LRB- cord-310304-f28tjmi8 22 79 6 6 CD cord-310304-f28tjmi8 22 80 ] ] -RRB- cord-310304-f28tjmi8 22 81 [ [ -LRB- cord-310304-f28tjmi8 22 82 7 7 CD cord-310304-f28tjmi8 22 83 ] ] -RRB- cord-310304-f28tjmi8 22 84 [ [ -LRB- cord-310304-f28tjmi8 22 85 8 8 CD cord-310304-f28tjmi8 22 86 ] ] -RRB- cord-310304-f28tjmi8 22 87 [ [ -LRB- cord-310304-f28tjmi8 22 88 9 9 CD cord-310304-f28tjmi8 22 89 ] ] -RRB- cord-310304-f28tjmi8 22 90 . . . cord-310304-f28tjmi8 23 1 The the DT cord-310304-f28tjmi8 23 2 World World NNP cord-310304-f28tjmi8 23 3 Health Health NNP cord-310304-f28tjmi8 23 4 Organization Organization NNP cord-310304-f28tjmi8 23 5 ( ( -LRB- cord-310304-f28tjmi8 23 6 WHO who WP cord-310304-f28tjmi8 23 7 ) ) -RRB- cord-310304-f28tjmi8 23 8 has have VBZ cord-310304-f28tjmi8 23 9 classified classify VBN cord-310304-f28tjmi8 23 10 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 23 11 as as IN cord-310304-f28tjmi8 23 12 a a DT cord-310304-f28tjmi8 23 13 β β NN cord-310304-f28tjmi8 23 14 - - HYPH cord-310304-f28tjmi8 23 15 CoV CoV NNP cord-310304-f28tjmi8 23 16 of of IN cord-310304-f28tjmi8 23 17 group group NNP cord-310304-f28tjmi8 23 18 2B 2b CD cord-310304-f28tjmi8 23 19 [ [ -LRB- cord-310304-f28tjmi8 23 20 10 10 CD cord-310304-f28tjmi8 23 21 ] ] -RRB- cord-310304-f28tjmi8 23 22 . . . cord-310304-f28tjmi8 24 1 CoVs CoVs NNP cord-310304-f28tjmi8 24 2 cause cause VBP cord-310304-f28tjmi8 24 3 respiratory respiratory JJ cord-310304-f28tjmi8 24 4 , , , cord-310304-f28tjmi8 24 5 enteric enteric JJ cord-310304-f28tjmi8 24 6 , , , cord-310304-f28tjmi8 24 7 hepatic hepatic JJ cord-310304-f28tjmi8 24 8 , , , cord-310304-f28tjmi8 24 9 and and CC cord-310304-f28tjmi8 24 10 neurological neurological JJ cord-310304-f28tjmi8 24 11 diseases disease NNS cord-310304-f28tjmi8 24 12 in in IN cord-310304-f28tjmi8 24 13 various various JJ cord-310304-f28tjmi8 24 14 animal animal NN cord-310304-f28tjmi8 24 15 species specie NNS cord-310304-f28tjmi8 24 16 , , , cord-310304-f28tjmi8 24 17 including include VBG cord-310304-f28tjmi8 24 18 camels camel NNS cord-310304-f28tjmi8 24 19 , , , cord-310304-f28tjmi8 24 20 cattle cattle NNS cord-310304-f28tjmi8 24 21 , , , cord-310304-f28tjmi8 24 22 cats cat NNS cord-310304-f28tjmi8 24 23 , , , cord-310304-f28tjmi8 24 24 and and CC cord-310304-f28tjmi8 24 25 bats bat NNS cord-310304-f28tjmi8 24 26 [ [ -LRB- cord-310304-f28tjmi8 24 27 11 11 CD cord-310304-f28tjmi8 24 28 , , , cord-310304-f28tjmi8 24 29 12 12 CD cord-310304-f28tjmi8 24 30 ] ] -RRB- cord-310304-f28tjmi8 24 31 . . . cord-310304-f28tjmi8 25 1 The the DT cord-310304-f28tjmi8 25 2 β β NN cord-310304-f28tjmi8 25 3 - - HYPH cord-310304-f28tjmi8 25 4 CoV cov NN cord-310304-f28tjmi8 25 5 lineages lineage NNS cord-310304-f28tjmi8 25 6 HCoV HCoV NNP cord-310304-f28tjmi8 25 7 - - HYPH cord-310304-f28tjmi8 25 8 OC43 OC43 NNP cord-310304-f28tjmi8 25 9 and and CC cord-310304-f28tjmi8 25 10 HCoV HCoV NNP cord-310304-f28tjmi8 25 11 - - HYPH cord-310304-f28tjmi8 25 12 HKU1 HKU1 NNP cord-310304-f28tjmi8 25 13 typically typically RB cord-310304-f28tjmi8 25 14 are be VBP cord-310304-f28tjmi8 25 15 associated associate VBN cord-310304-f28tjmi8 25 16 with with IN cord-310304-f28tjmi8 25 17 self self NN cord-310304-f28tjmi8 25 18 - - HYPH cord-310304-f28tjmi8 25 19 limiting limit VBG cord-310304-f28tjmi8 25 20 upper upper JJ cord-310304-f28tjmi8 25 21 respiratory respiratory JJ cord-310304-f28tjmi8 25 22 infections infection NNS cord-310304-f28tjmi8 25 23 in in IN cord-310304-f28tjmi8 25 24 immunocompetent immunocompetent JJ cord-310304-f28tjmi8 25 25 hosts host NNS cord-310304-f28tjmi8 25 26 and and CC cord-310304-f28tjmi8 25 27 occasionally occasionally RB cord-310304-f28tjmi8 25 28 lower low JJR cord-310304-f28tjmi8 25 29 respiratory respiratory JJ cord-310304-f28tjmi8 25 30 tract tract NN cord-310304-f28tjmi8 25 31 infections infection NNS cord-310304-f28tjmi8 25 32 in in IN cord-310304-f28tjmi8 25 33 immunocompromised immunocompromised JJ cord-310304-f28tjmi8 25 34 hosts host NNS cord-310304-f28tjmi8 25 35 and and CC cord-310304-f28tjmi8 25 36 the the DT cord-310304-f28tjmi8 25 37 elderly elderly JJ cord-310304-f28tjmi8 25 38 [ [ -LRB- cord-310304-f28tjmi8 25 39 13 13 CD cord-310304-f28tjmi8 25 40 , , , cord-310304-f28tjmi8 25 41 14 14 CD cord-310304-f28tjmi8 25 42 ] ] -RRB- cord-310304-f28tjmi8 25 43 . . . cord-310304-f28tjmi8 26 1 Examination examination NN cord-310304-f28tjmi8 26 2 of of IN cord-310304-f28tjmi8 26 3 the the DT cord-310304-f28tjmi8 26 4 viral viral JJ cord-310304-f28tjmi8 26 5 evolution evolution NN cord-310304-f28tjmi8 26 6 reveals reveal VBZ cord-310304-f28tjmi8 26 7 that that IN cord-310304-f28tjmi8 26 8 bats bat NNS cord-310304-f28tjmi8 26 9 and and CC cord-310304-f28tjmi8 26 10 rodents rodent NNS cord-310304-f28tjmi8 26 11 are be VBP cord-310304-f28tjmi8 26 12 gene gene NN cord-310304-f28tjmi8 26 13 sources source NNS cord-310304-f28tjmi8 26 14 for for IN cord-310304-f28tjmi8 26 15 most most JJS cord-310304-f28tjmi8 26 16 α α NN cord-310304-f28tjmi8 26 17 - - HYPH cord-310304-f28tjmi8 26 18 Covs Covs NNP cord-310304-f28tjmi8 26 19 and and CC cord-310304-f28tjmi8 26 20 β β NN cord-310304-f28tjmi8 26 21 - - HYPH cord-310304-f28tjmi8 26 22 CoVs CoVs NNP cord-310304-f28tjmi8 26 23 , , , cord-310304-f28tjmi8 26 24 whereas whereas IN cord-310304-f28tjmi8 26 25 avian avian JJ cord-310304-f28tjmi8 26 26 species specie NNS cord-310304-f28tjmi8 26 27 are be VBP cord-310304-f28tjmi8 26 28 the the DT cord-310304-f28tjmi8 26 29 proposed propose VBN cord-310304-f28tjmi8 26 30 gene gene NN cord-310304-f28tjmi8 26 31 sources source NNS cord-310304-f28tjmi8 26 32 of of IN cord-310304-f28tjmi8 26 33 most most JJS cord-310304-f28tjmi8 26 34 δ δ NN cord-310304-f28tjmi8 26 35 - - HYPH cord-310304-f28tjmi8 26 36 CoVs CoVs NNP cord-310304-f28tjmi8 26 37 and and CC cord-310304-f28tjmi8 26 38 γ γ NN cord-310304-f28tjmi8 26 39 - - HYPH cord-310304-f28tjmi8 26 40 CoVs CoVs NNP cord-310304-f28tjmi8 26 41 [ [ -LRB- cord-310304-f28tjmi8 26 42 15 15 CD cord-310304-f28tjmi8 26 43 ] ] -RRB- cord-310304-f28tjmi8 26 44 . . . cord-310304-f28tjmi8 27 1 CoVs CoVs NNP cord-310304-f28tjmi8 27 2 often often RB cord-310304-f28tjmi8 28 1 The the DT cord-310304-f28tjmi8 28 2 health health NN cord-310304-f28tjmi8 28 3 inequities inequity NNS cord-310304-f28tjmi8 28 4 in in IN cord-310304-f28tjmi8 28 5 the the DT cord-310304-f28tjmi8 28 6 US US NNP cord-310304-f28tjmi8 28 7 that that WDT cord-310304-f28tjmi8 28 8 impact impact NN cord-310304-f28tjmi8 28 9 minority minority NN cord-310304-f28tjmi8 28 10 communities community NNS cord-310304-f28tjmi8 28 11 were be VBD cord-310304-f28tjmi8 28 12 well well RB cord-310304-f28tjmi8 28 13 in in IN cord-310304-f28tjmi8 28 14 place place NN cord-310304-f28tjmi8 28 15 prior prior RB cord-310304-f28tjmi8 28 16 to to IN cord-310304-f28tjmi8 28 17 the the DT cord-310304-f28tjmi8 28 18 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 28 19 pandemic pandemic NN cord-310304-f28tjmi8 28 20 . . . cord-310304-f28tjmi8 29 1 These these DT cord-310304-f28tjmi8 29 2 inequities inequity NNS cord-310304-f28tjmi8 29 3 have have VBP cord-310304-f28tjmi8 29 4 become become VBN cord-310304-f28tjmi8 29 5 more more RBR cord-310304-f28tjmi8 29 6 evident evident JJ cord-310304-f28tjmi8 29 7 in in IN cord-310304-f28tjmi8 29 8 some some DT cord-310304-f28tjmi8 29 9 cities city NNS cord-310304-f28tjmi8 29 10 and and CC cord-310304-f28tjmi8 29 11 states state NNS cord-310304-f28tjmi8 29 12 . . . cord-310304-f28tjmi8 30 1 In in IN cord-310304-f28tjmi8 30 2 Chicago Chicago NNP cord-310304-f28tjmi8 30 3 , , , cord-310304-f28tjmi8 30 4 AAs aa NNS cord-310304-f28tjmi8 30 5 make make VBP cord-310304-f28tjmi8 30 6 up up RP cord-310304-f28tjmi8 30 7 30 30 CD cord-310304-f28tjmi8 30 8 % % NN cord-310304-f28tjmi8 30 9 of of IN cord-310304-f28tjmi8 30 10 the the DT cord-310304-f28tjmi8 30 11 population population NN cord-310304-f28tjmi8 30 12 ; ; : cord-310304-f28tjmi8 30 13 yet yet RB cord-310304-f28tjmi8 30 14 , , , cord-310304-f28tjmi8 30 15 they -PRON- PRP cord-310304-f28tjmi8 30 16 represent represent VBP cord-310304-f28tjmi8 30 17 50 50 CD cord-310304-f28tjmi8 30 18 % % NN cord-310304-f28tjmi8 30 19 of of IN cord-310304-f28tjmi8 30 20 COVID-19 covid-19 JJ cord-310304-f28tjmi8 30 21 cases case NNS cord-310304-f28tjmi8 30 22 and and CC cord-310304-f28tjmi8 30 23 approximately approximately RB cord-310304-f28tjmi8 30 24 70 70 CD cord-310304-f28tjmi8 30 25 % % NN cord-310304-f28tjmi8 30 26 of of IN cord-310304-f28tjmi8 30 27 COVID-19 covid-19 JJ cord-310304-f28tjmi8 30 28 deaths death NNS cord-310304-f28tjmi8 30 29 , , , cord-310304-f28tjmi8 30 30 most most JJS cord-310304-f28tjmi8 30 31 of of IN cord-310304-f28tjmi8 30 32 which which WDT cord-310304-f28tjmi8 30 33 are be VBP cord-310304-f28tjmi8 30 34 concentrated concentrate VBN cord-310304-f28tjmi8 30 35 in in IN cord-310304-f28tjmi8 30 36 small small JJ cord-310304-f28tjmi8 30 37 numbers number NNS cord-310304-f28tjmi8 30 38 of of IN cord-310304-f28tjmi8 30 39 the the DT cord-310304-f28tjmi8 30 40 most most RBS cord-310304-f28tjmi8 30 41 vulnerable vulnerable JJ cord-310304-f28tjmi8 30 42 communities community NNS cord-310304-f28tjmi8 30 43 [ [ -LRB- cord-310304-f28tjmi8 30 44 27 27 CD cord-310304-f28tjmi8 30 45 ] ] -RRB- cord-310304-f28tjmi8 30 46 . . . cord-310304-f28tjmi8 31 1 In in IN cord-310304-f28tjmi8 31 2 the the DT cord-310304-f28tjmi8 31 3 states state NNS cord-310304-f28tjmi8 31 4 of of IN cord-310304-f28tjmi8 31 5 Louisiana Louisiana NNP cord-310304-f28tjmi8 31 6 and and CC cord-310304-f28tjmi8 31 7 Michigan Michigan NNP cord-310304-f28tjmi8 31 8 , , , cord-310304-f28tjmi8 31 9 AAs aa NNS cord-310304-f28tjmi8 31 10 are be VBP cord-310304-f28tjmi8 31 11 impacted impact VBN cord-310304-f28tjmi8 31 12 disproportionately disproportionately RB cord-310304-f28tjmi8 31 13 by by IN cord-310304-f28tjmi8 31 14 COVID-19 covid-19 JJ cord-310304-f28tjmi8 31 15 deaths death NNS cord-310304-f28tjmi8 31 16 [ [ -LRB- cord-310304-f28tjmi8 31 17 28 28 CD cord-310304-f28tjmi8 31 18 ] ] -RRB- cord-310304-f28tjmi8 31 19 : : : cord-310304-f28tjmi8 31 20 Blacks black NNS cord-310304-f28tjmi8 31 21 represent represent VBP cord-310304-f28tjmi8 31 22 32.2 32.2 CD cord-310304-f28tjmi8 31 23 % % NN cord-310304-f28tjmi8 31 24 and and CC cord-310304-f28tjmi8 31 25 14 14 CD cord-310304-f28tjmi8 31 26 % % NN cord-310304-f28tjmi8 31 27 , , , cord-310304-f28tjmi8 31 28 respectively respectively RB cord-310304-f28tjmi8 31 29 , , , cord-310304-f28tjmi8 31 30 and and CC cord-310304-f28tjmi8 31 31 account account VBP cord-310304-f28tjmi8 31 32 for for IN cord-310304-f28tjmi8 31 33 70.5 70.5 CD cord-310304-f28tjmi8 31 34 % % NN cord-310304-f28tjmi8 31 35 and and CC cord-310304-f28tjmi8 31 36 40 40 CD cord-310304-f28tjmi8 31 37 % % NN cord-310304-f28tjmi8 31 38 of of IN cord-310304-f28tjmi8 31 39 COVID-19 covid-19 JJ cord-310304-f28tjmi8 31 40 deaths death NNS cord-310304-f28tjmi8 31 41 , , , cord-310304-f28tjmi8 31 42 respectively respectively RB cord-310304-f28tjmi8 31 43 [ [ -LRB- cord-310304-f28tjmi8 31 44 29 29 CD cord-310304-f28tjmi8 31 45 ] ] -RRB- cord-310304-f28tjmi8 31 46 . . . cord-310304-f28tjmi8 32 1 In in IN cord-310304-f28tjmi8 32 2 New New NNP cord-310304-f28tjmi8 32 3 York York NNP cord-310304-f28tjmi8 32 4 City City NNP cord-310304-f28tjmi8 32 5 , , , cord-310304-f28tjmi8 32 6 which which WDT cord-310304-f28tjmi8 32 7 had have VBD cord-310304-f28tjmi8 32 8 the the DT cord-310304-f28tjmi8 32 9 largest large JJS cord-310304-f28tjmi8 32 10 number number NN cord-310304-f28tjmi8 32 11 of of IN cord-310304-f28tjmi8 32 12 COVID-19 covid-19 JJ cord-310304-f28tjmi8 32 13 cases case NNS cord-310304-f28tjmi8 32 14 and and CC cord-310304-f28tjmi8 32 15 the the DT cord-310304-f28tjmi8 32 16 highest high JJS cord-310304-f28tjmi8 32 17 number number NN cord-310304-f28tjmi8 32 18 of of IN cord-310304-f28tjmi8 32 19 deaths death NNS cord-310304-f28tjmi8 32 20 due due JJ cord-310304-f28tjmi8 32 21 to to IN cord-310304-f28tjmi8 32 22 COVID-19 covid-19 VB cord-310304-f28tjmi8 32 23 in in IN cord-310304-f28tjmi8 32 24 the the DT cord-310304-f28tjmi8 32 25 US US NNP cord-310304-f28tjmi8 32 26 , , , cord-310304-f28tjmi8 32 27 minority minority NN cord-310304-f28tjmi8 32 28 communities community NNS cord-310304-f28tjmi8 32 29 disproportionately disproportionately RB cord-310304-f28tjmi8 32 30 are be VBP cord-310304-f28tjmi8 32 31 impacted impact VBN cord-310304-f28tjmi8 32 32 , , , cord-310304-f28tjmi8 32 33 as as IN cord-310304-f28tjmi8 32 34 AAs aas NN cord-310304-f28tjmi8 32 35 and and CC cord-310304-f28tjmi8 32 36 H H NNP cord-310304-f28tjmi8 32 37 / / SYM cord-310304-f28tjmi8 32 38 Ls Ls NNP cord-310304-f28tjmi8 32 39 account account VBP cord-310304-f28tjmi8 32 40 for for IN cord-310304-f28tjmi8 32 41 22 22 CD cord-310304-f28tjmi8 32 42 % % NN cord-310304-f28tjmi8 32 43 and and CC cord-310304-f28tjmi8 32 44 29 29 CD cord-310304-f28tjmi8 32 45 % % NN cord-310304-f28tjmi8 32 46 of of IN cord-310304-f28tjmi8 32 47 the the DT cord-310304-f28tjmi8 32 48 population population NN cord-310304-f28tjmi8 32 49 , , , cord-310304-f28tjmi8 32 50 respectively respectively RB cord-310304-f28tjmi8 32 51 , , , cord-310304-f28tjmi8 32 52 and and CC cord-310304-f28tjmi8 32 53 account account VBP cord-310304-f28tjmi8 32 54 for for IN cord-310304-f28tjmi8 32 55 28 28 CD cord-310304-f28tjmi8 32 56 % % NN cord-310304-f28tjmi8 32 57 and and CC cord-310304-f28tjmi8 32 58 34 34 CD cord-310304-f28tjmi8 32 59 % % NN cord-310304-f28tjmi8 32 60 of of IN cord-310304-f28tjmi8 32 61 deaths death NNS cord-310304-f28tjmi8 32 62 , , , cord-310304-f28tjmi8 32 63 respectively respectively RB cord-310304-f28tjmi8 32 64 [ [ -LRB- cord-310304-f28tjmi8 32 65 30 30 CD cord-310304-f28tjmi8 32 66 ] ] -RRB- cord-310304-f28tjmi8 32 67 . . . cord-310304-f28tjmi8 33 1 An an DT cord-310304-f28tjmi8 33 2 examination examination NN cord-310304-f28tjmi8 33 3 of of IN cord-310304-f28tjmi8 33 4 131 131 CD cord-310304-f28tjmi8 33 5 predominantly predominantly RB cord-310304-f28tjmi8 33 6 AA AA NNP cord-310304-f28tjmi8 33 7 counties county NNS cord-310304-f28tjmi8 33 8 shows show VBZ cord-310304-f28tjmi8 33 9 a a DT cord-310304-f28tjmi8 33 10 COVID-19 covid-19 CD cord-310304-f28tjmi8 33 11 infection infection NN cord-310304-f28tjmi8 33 12 rate rate NN cord-310304-f28tjmi8 33 13 of of IN cord-310304-f28tjmi8 33 14 137.5 137.5 CD cord-310304-f28tjmi8 33 15 per per IN cord-310304-f28tjmi8 33 16 100,000 100,000 CD cord-310304-f28tjmi8 33 17 and and CC cord-310304-f28tjmi8 33 18 a a DT cord-310304-f28tjmi8 33 19 death death NN cord-310304-f28tjmi8 33 20 rate rate NN cord-310304-f28tjmi8 33 21 of of IN cord-310304-f28tjmi8 33 22 6.3 6.3 CD cord-310304-f28tjmi8 33 23 per per IN cord-310304-f28tjmi8 33 24 100,000 100,000 CD cord-310304-f28tjmi8 33 25 , , , cord-310304-f28tjmi8 33 26 which which WDT cord-310304-f28tjmi8 33 27 is be VBZ cord-310304-f28tjmi8 33 28 three three CD cord-310304-f28tjmi8 33 29 times time NNS cord-310304-f28tjmi8 33 30 higher high JJR cord-310304-f28tjmi8 33 31 than than IN cord-310304-f28tjmi8 33 32 the the DT cord-310304-f28tjmi8 33 33 predominant predominant JJ cord-310304-f28tjmi8 33 34 NHW NHW NNP cord-310304-f28tjmi8 33 35 counties county NNS cord-310304-f28tjmi8 33 36 . . . cord-310304-f28tjmi8 34 1 Moreover moreover RB cord-310304-f28tjmi8 34 2 , , , cord-310304-f28tjmi8 34 3 the the DT cord-310304-f28tjmi8 34 4 death death NN cord-310304-f28tjmi8 34 5 rate rate NN cord-310304-f28tjmi8 34 6 for for IN cord-310304-f28tjmi8 34 7 the the DT cord-310304-f28tjmi8 34 8 AA AA NNP cord-310304-f28tjmi8 34 9 counties county NNS cord-310304-f28tjmi8 34 10 were be VBD cord-310304-f28tjmi8 34 11 found find VBN cord-310304-f28tjmi8 34 12 to to TO cord-310304-f28tjmi8 34 13 be be VB cord-310304-f28tjmi8 34 14 six six CD cord-310304-f28tjmi8 34 15 times time NNS cord-310304-f28tjmi8 34 16 higher high JJR cord-310304-f28tjmi8 34 17 than than IN cord-310304-f28tjmi8 34 18 the the DT cord-310304-f28tjmi8 34 19 rate rate NN cord-310304-f28tjmi8 34 20 observed observe VBN cord-310304-f28tjmi8 34 21 in in IN cord-310304-f28tjmi8 34 22 predominant predominant JJ cord-310304-f28tjmi8 34 23 white white JJ cord-310304-f28tjmi8 34 24 counties county NNS cord-310304-f28tjmi8 34 25 . . . cord-310304-f28tjmi8 35 1 Taken take VBN cord-310304-f28tjmi8 35 2 together together RB cord-310304-f28tjmi8 35 3 , , , cord-310304-f28tjmi8 35 4 a a DT cord-310304-f28tjmi8 35 5 disproportionate disproportionate JJ cord-310304-f28tjmi8 35 6 burden burden NN cord-310304-f28tjmi8 35 7 of of IN cord-310304-f28tjmi8 35 8 COVID-19 covid-19 JJ cord-310304-f28tjmi8 35 9 morbidity morbidity NN cord-310304-f28tjmi8 35 10 and and CC cord-310304-f28tjmi8 35 11 mortality mortality NN cord-310304-f28tjmi8 35 12 , , , cord-310304-f28tjmi8 35 13 which which WDT cord-310304-f28tjmi8 35 14 will will MD cord-310304-f28tjmi8 35 15 require require VB cord-310304-f28tjmi8 35 16 further further JJ cord-310304-f28tjmi8 35 17 investigation investigation NN cord-310304-f28tjmi8 35 18 , , , cord-310304-f28tjmi8 35 19 exists exist VBZ cord-310304-f28tjmi8 35 20 among among IN cord-310304-f28tjmi8 35 21 minority minority NN cord-310304-f28tjmi8 35 22 communities community NNS cord-310304-f28tjmi8 35 23 in in IN cord-310304-f28tjmi8 35 24 the the DT cord-310304-f28tjmi8 35 25 US US NNP cord-310304-f28tjmi8 35 26 . . . cord-310304-f28tjmi8 36 1 It -PRON- PRP cord-310304-f28tjmi8 36 2 is be VBZ cord-310304-f28tjmi8 36 3 evident evident JJ cord-310304-f28tjmi8 36 4 that that IN cord-310304-f28tjmi8 36 5 social social JJ cord-310304-f28tjmi8 36 6 determinants determinant NNS cord-310304-f28tjmi8 36 7 of of IN cord-310304-f28tjmi8 36 8 health health NN cord-310304-f28tjmi8 36 9 play play VBP cord-310304-f28tjmi8 36 10 a a DT cord-310304-f28tjmi8 36 11 critical critical JJ cord-310304-f28tjmi8 36 12 role role NN cord-310304-f28tjmi8 36 13 in in IN cord-310304-f28tjmi8 36 14 population population NN cord-310304-f28tjmi8 36 15 - - HYPH cord-310304-f28tjmi8 36 16 level level NN cord-310304-f28tjmi8 36 17 health health NN cord-310304-f28tjmi8 36 18 disparities disparity NNS cord-310304-f28tjmi8 36 19 beyond beyond IN cord-310304-f28tjmi8 36 20 the the DT cord-310304-f28tjmi8 36 21 comorbidities comorbiditie NNS cord-310304-f28tjmi8 36 22 associated associate VBN cord-310304-f28tjmi8 36 23 with with IN cord-310304-f28tjmi8 36 24 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 36 25 in in IN cord-310304-f28tjmi8 36 26 minority minority NN cord-310304-f28tjmi8 36 27 communities community NNS cord-310304-f28tjmi8 36 28 . . . cord-310304-f28tjmi8 37 1 In in IN cord-310304-f28tjmi8 37 2 the the DT cord-310304-f28tjmi8 37 3 early early JJ cord-310304-f28tjmi8 37 4 stages stage NNS cord-310304-f28tjmi8 37 5 of of IN cord-310304-f28tjmi8 37 6 the the DT cord-310304-f28tjmi8 37 7 pandemic pandemic NN cord-310304-f28tjmi8 37 8 in in IN cord-310304-f28tjmi8 37 9 the the DT cord-310304-f28tjmi8 37 10 US US NNP cord-310304-f28tjmi8 37 11 , , , cord-310304-f28tjmi8 37 12 dismissing dismiss VBG cord-310304-f28tjmi8 37 13 COVID-19 COVID-19 , cord-310304-f28tjmi8 37 14 as as IN cord-310304-f28tjmi8 37 15 not not RB cord-310304-f28tjmi8 37 16 infecting infect VBG cord-310304-f28tjmi8 37 17 AAs aa NNS cord-310304-f28tjmi8 37 18 may may MD cord-310304-f28tjmi8 37 19 have have VB cord-310304-f28tjmi8 37 20 created create VBN cord-310304-f28tjmi8 37 21 a a DT cord-310304-f28tjmi8 37 22 lack lack NN cord-310304-f28tjmi8 37 23 of of IN cord-310304-f28tjmi8 37 24 awareness awareness NN cord-310304-f28tjmi8 37 25 and and CC cord-310304-f28tjmi8 37 26 best good JJS cord-310304-f28tjmi8 37 27 practices practice NNS cord-310304-f28tjmi8 37 28 , , , cord-310304-f28tjmi8 37 29 including include VBG cord-310304-f28tjmi8 37 30 proper proper JJ cord-310304-f28tjmi8 37 31 hand hand NN cord-310304-f28tjmi8 37 32 hygiene hygiene NN cord-310304-f28tjmi8 37 33 , , , cord-310304-f28tjmi8 37 34 use use NN cord-310304-f28tjmi8 37 35 of of IN cord-310304-f28tjmi8 37 36 masks mask NNS cord-310304-f28tjmi8 37 37 in in IN cord-310304-f28tjmi8 37 38 public public JJ cord-310304-f28tjmi8 37 39 places place NNS cord-310304-f28tjmi8 37 40 , , , cord-310304-f28tjmi8 37 41 and and CC cord-310304-f28tjmi8 37 42 social social JJ cord-310304-f28tjmi8 37 43 distancing distancing NN cord-310304-f28tjmi8 37 44 and and CC cord-310304-f28tjmi8 37 45 physical physical JJ cord-310304-f28tjmi8 37 46 isolation isolation NN cord-310304-f28tjmi8 37 47 , , , cord-310304-f28tjmi8 37 48 likely likely RB cord-310304-f28tjmi8 37 49 contributing contribute VBG cord-310304-f28tjmi8 37 50 to to IN cord-310304-f28tjmi8 37 51 SARS SARS NNP cord-310304-f28tjmi8 37 52 - - HYPH cord-310304-f28tjmi8 37 53 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 37 54 transmission transmission NN cord-310304-f28tjmi8 37 55 in in IN cord-310304-f28tjmi8 37 56 these these DT cord-310304-f28tjmi8 37 57 communities community NNS cord-310304-f28tjmi8 37 58 [ [ -LRB- cord-310304-f28tjmi8 37 59 31 31 CD cord-310304-f28tjmi8 37 60 ] ] -RRB- cord-310304-f28tjmi8 37 61 . . . cord-310304-f28tjmi8 38 1 Even even RB cord-310304-f28tjmi8 38 2 were be VBD cord-310304-f28tjmi8 38 3 that that IN cord-310304-f28tjmi8 38 4 not not RB cord-310304-f28tjmi8 38 5 the the DT cord-310304-f28tjmi8 38 6 case case NN cord-310304-f28tjmi8 38 7 , , , cord-310304-f28tjmi8 38 8 among among IN cord-310304-f28tjmi8 38 9 vulnerable vulnerable JJ cord-310304-f28tjmi8 38 10 populations population NNS cord-310304-f28tjmi8 38 11 with with IN cord-310304-f28tjmi8 38 12 low low JJ cord-310304-f28tjmi8 38 13 socioeconomic socioeconomic JJ cord-310304-f28tjmi8 38 14 status status NN cord-310304-f28tjmi8 38 15 , , , cord-310304-f28tjmi8 38 16 these these DT cord-310304-f28tjmi8 38 17 transmission transmission NN cord-310304-f28tjmi8 38 18 - - HYPH cord-310304-f28tjmi8 38 19 mitigating mitigate VBG cord-310304-f28tjmi8 38 20 practices practice NNS cord-310304-f28tjmi8 38 21 are be VBP cord-310304-f28tjmi8 38 22 difficult difficult JJ cord-310304-f28tjmi8 38 23 to to TO cord-310304-f28tjmi8 38 24 maintain maintain VB cord-310304-f28tjmi8 38 25 over over IN cord-310304-f28tjmi8 38 26 time time NN cord-310304-f28tjmi8 38 27 . . . cord-310304-f28tjmi8 39 1 Racial racial JJ cord-310304-f28tjmi8 39 2 and and CC cord-310304-f28tjmi8 39 3 ethnic ethnic JJ cord-310304-f28tjmi8 39 4 disparities disparity NNS cord-310304-f28tjmi8 39 5 in in IN cord-310304-f28tjmi8 39 6 the the DT cord-310304-f28tjmi8 39 7 prevalence prevalence NN cord-310304-f28tjmi8 39 8 of of IN cord-310304-f28tjmi8 39 9 type type NN cord-310304-f28tjmi8 39 10 2 2 CD cord-310304-f28tjmi8 39 11 diabetes diabetes NN cord-310304-f28tjmi8 39 12 ( ( -LRB- cord-310304-f28tjmi8 39 13 T2D t2d LS cord-310304-f28tjmi8 39 14 ) ) -RRB- cord-310304-f28tjmi8 39 15 among among IN cord-310304-f28tjmi8 39 16 adult adult NN cord-310304-f28tjmi8 39 17 minority minority NN cord-310304-f28tjmi8 39 18 populations population NNS cord-310304-f28tjmi8 39 19 have have VBP cord-310304-f28tjmi8 39 20 been be VBN cord-310304-f28tjmi8 39 21 documented document VBN cord-310304-f28tjmi8 39 22 [ [ -LRB- cord-310304-f28tjmi8 39 23 32 32 CD cord-310304-f28tjmi8 39 24 , , , cord-310304-f28tjmi8 39 25 33 33 CD cord-310304-f28tjmi8 39 26 ] ] -RRB- cord-310304-f28tjmi8 39 27 . . . cord-310304-f28tjmi8 40 1 More more RBR cord-310304-f28tjmi8 40 2 recently recently RB cord-310304-f28tjmi8 40 3 , , , cord-310304-f28tjmi8 40 4 the the DT cord-310304-f28tjmi8 40 5 global global JJ cord-310304-f28tjmi8 40 6 epidemic epidemic NN cord-310304-f28tjmi8 40 7 of of IN cord-310304-f28tjmi8 40 8 childhood childhood NN cord-310304-f28tjmi8 40 9 obesity obesity NN cord-310304-f28tjmi8 40 10 has have VBZ cord-310304-f28tjmi8 40 11 contributed contribute VBN cord-310304-f28tjmi8 40 12 greatly greatly RB cord-310304-f28tjmi8 40 13 to to IN cord-310304-f28tjmi8 40 14 the the DT cord-310304-f28tjmi8 40 15 higher high JJR cord-310304-f28tjmi8 40 16 prevalence prevalence NN cord-310304-f28tjmi8 40 17 of of IN cord-310304-f28tjmi8 40 18 T2D t2d DT cord-310304-f28tjmi8 40 19 among among IN cord-310304-f28tjmi8 40 20 adolescents adolescent NNS cord-310304-f28tjmi8 40 21 who who WP cord-310304-f28tjmi8 40 22 have have VBP cord-310304-f28tjmi8 40 23 more more JJR cord-310304-f28tjmi8 40 24 progressive progressive JJ cord-310304-f28tjmi8 40 25 clinical clinical JJ cord-310304-f28tjmi8 40 26 presentations presentation NNS cord-310304-f28tjmi8 40 27 of of IN cord-310304-f28tjmi8 40 28 chronic chronic JJ cord-310304-f28tjmi8 40 29 kidney kidney NN cord-310304-f28tjmi8 40 30 disease disease NN cord-310304-f28tjmi8 40 31 ( ( -LRB- cord-310304-f28tjmi8 40 32 CKD CKD NNP cord-310304-f28tjmi8 40 33 ) ) -RRB- cord-310304-f28tjmi8 40 34 , , , cord-310304-f28tjmi8 40 35 CVD CVD NNP cord-310304-f28tjmi8 40 36 , , , cord-310304-f28tjmi8 40 37 diabetes diabetes NN cord-310304-f28tjmi8 40 38 - - HYPH cord-310304-f28tjmi8 40 39 related relate VBN cord-310304-f28tjmi8 40 40 eye eye NN cord-310304-f28tjmi8 40 41 disease disease NN cord-310304-f28tjmi8 40 42 , , , cord-310304-f28tjmi8 40 43 and and CC cord-310304-f28tjmi8 40 44 poor poor JJ cord-310304-f28tjmi8 40 45 glycemic glycemic NN cord-310304-f28tjmi8 40 46 control control NN cord-310304-f28tjmi8 40 47 over over IN cord-310304-f28tjmi8 40 48 time time NN cord-310304-f28tjmi8 40 49 [ [ -LRB- cord-310304-f28tjmi8 40 50 34 34 CD cord-310304-f28tjmi8 40 51 ] ] -RRB- cord-310304-f28tjmi8 40 52 . . . cord-310304-f28tjmi8 41 1 Higher high JJR cord-310304-f28tjmi8 41 2 rates rate NNS cord-310304-f28tjmi8 41 3 of of IN cord-310304-f28tjmi8 41 4 T2D t2d DT cord-310304-f28tjmi8 41 5 are be VBP cord-310304-f28tjmi8 41 6 seen see VBN cord-310304-f28tjmi8 41 7 among among IN cord-310304-f28tjmi8 41 8 minority minority NN cord-310304-f28tjmi8 41 9 youth youth NN cord-310304-f28tjmi8 41 10 when when WRB cord-310304-f28tjmi8 41 11 compared compare VBN cord-310304-f28tjmi8 41 12 with with IN cord-310304-f28tjmi8 41 13 NHW NHW NNP cord-310304-f28tjmi8 41 14 youth youth NN cord-310304-f28tjmi8 41 15 [ [ -LRB- cord-310304-f28tjmi8 41 16 35 35 CD cord-310304-f28tjmi8 41 17 ] ] -RRB- cord-310304-f28tjmi8 41 18 . . . cord-310304-f28tjmi8 42 1 Approximately approximately RB cord-310304-f28tjmi8 42 2 80 80 CD cord-310304-f28tjmi8 42 3 % % NN cord-310304-f28tjmi8 42 4 of of IN cord-310304-f28tjmi8 42 5 youth youth NN cord-310304-f28tjmi8 42 6 with with IN cord-310304-f28tjmi8 42 7 T2D t2d CD cord-310304-f28tjmi8 42 8 are be VBP cord-310304-f28tjmi8 42 9 from from IN cord-310304-f28tjmi8 42 10 minority minority NN cord-310304-f28tjmi8 42 11 backgrounds background NNS cord-310304-f28tjmi8 42 12 [ [ -LRB- cord-310304-f28tjmi8 42 13 36 36 CD cord-310304-f28tjmi8 42 14 ] ] -RRB- cord-310304-f28tjmi8 42 15 . . . cord-310304-f28tjmi8 43 1 In in IN cord-310304-f28tjmi8 43 2 addition addition NN cord-310304-f28tjmi8 43 3 , , , cord-310304-f28tjmi8 43 4 health health NN cord-310304-f28tjmi8 43 5 disparities disparity NNS cord-310304-f28tjmi8 43 6 for for IN cord-310304-f28tjmi8 43 7 T2D t2d DT cord-310304-f28tjmi8 43 8 are be VBP cord-310304-f28tjmi8 43 9 present present JJ cord-310304-f28tjmi8 43 10 in in IN cord-310304-f28tjmi8 43 11 adults adult NNS cord-310304-f28tjmi8 43 12 and and CC cord-310304-f28tjmi8 43 13 youth youth NN cord-310304-f28tjmi8 43 14 among among IN cord-310304-f28tjmi8 43 15 racial racial JJ cord-310304-f28tjmi8 43 16 and and CC cord-310304-f28tjmi8 43 17 ethnic ethnic JJ cord-310304-f28tjmi8 43 18 minorities minority NNS cord-310304-f28tjmi8 43 19 , , , cord-310304-f28tjmi8 43 20 and and CC cord-310304-f28tjmi8 43 21 this this DT cord-310304-f28tjmi8 43 22 likely likely RB cord-310304-f28tjmi8 43 23 will will MD cord-310304-f28tjmi8 43 24 impact impact VB cord-310304-f28tjmi8 43 25 their -PRON- PRP$ cord-310304-f28tjmi8 43 26 response response NN cord-310304-f28tjmi8 43 27 to to IN cord-310304-f28tjmi8 43 28 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 43 29 . . . cord-310304-f28tjmi8 44 1 COVID-19 covid-19 JJ cord-310304-f28tjmi8 44 2 patients patient NNS cord-310304-f28tjmi8 44 3 with with IN cord-310304-f28tjmi8 44 4 diabetes diabete NNS cord-310304-f28tjmi8 44 5 are be VBP cord-310304-f28tjmi8 44 6 at at IN cord-310304-f28tjmi8 44 7 increased increase VBN cord-310304-f28tjmi8 44 8 risk risk NN cord-310304-f28tjmi8 44 9 of of IN cord-310304-f28tjmi8 44 10 having have VBG cord-310304-f28tjmi8 44 11 adverse adverse JJ cord-310304-f28tjmi8 44 12 clinical clinical JJ cord-310304-f28tjmi8 44 13 complications complication NNS cord-310304-f28tjmi8 44 14 , , , cord-310304-f28tjmi8 44 15 including include VBG cord-310304-f28tjmi8 44 16 death death NN cord-310304-f28tjmi8 44 17 [ [ -LRB- cord-310304-f28tjmi8 44 18 37 37 CD cord-310304-f28tjmi8 44 19 , , , cord-310304-f28tjmi8 44 20 38 38 CD cord-310304-f28tjmi8 44 21 ] ] -RRB- cord-310304-f28tjmi8 44 22 . . . cord-310304-f28tjmi8 45 1 Maintaining maintain VBG cord-310304-f28tjmi8 45 2 glycemic glycemic JJ cord-310304-f28tjmi8 45 3 control control NN cord-310304-f28tjmi8 45 4 in in IN cord-310304-f28tjmi8 45 5 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 45 6 patients patient NNS cord-310304-f28tjmi8 45 7 is be VBZ cord-310304-f28tjmi8 45 8 essential essential JJ cord-310304-f28tjmi8 45 9 , , , cord-310304-f28tjmi8 45 10 as as IN cord-310304-f28tjmi8 45 11 hyperglycemia hyperglycemia NN cord-310304-f28tjmi8 45 12 could could MD cord-310304-f28tjmi8 45 13 affect affect VB cord-310304-f28tjmi8 45 14 pulmonary pulmonary JJ cord-310304-f28tjmi8 45 15 function function NN cord-310304-f28tjmi8 45 16 , , , cord-310304-f28tjmi8 45 17 the the DT cord-310304-f28tjmi8 45 18 immune immune JJ cord-310304-f28tjmi8 45 19 response response NN cord-310304-f28tjmi8 45 20 to to IN cord-310304-f28tjmi8 45 21 infection infection NN cord-310304-f28tjmi8 45 22 , , , cord-310304-f28tjmi8 45 23 and and CC cord-310304-f28tjmi8 45 24 the the DT cord-310304-f28tjmi8 45 25 development development NN cord-310304-f28tjmi8 45 26 of of IN cord-310304-f28tjmi8 45 27 the the DT cord-310304-f28tjmi8 45 28 pro pro JJ cord-310304-f28tjmi8 45 29 - - JJ cord-310304-f28tjmi8 45 30 inflammatory inflammatory JJ cord-310304-f28tjmi8 45 31 cytokine cytokine NN cord-310304-f28tjmi8 45 32 storm storm NN cord-310304-f28tjmi8 45 33 associated associate VBN cord-310304-f28tjmi8 45 34 with with IN cord-310304-f28tjmi8 45 35 more more RBR cord-310304-f28tjmi8 45 36 severe severe JJ cord-310304-f28tjmi8 45 37 clinical clinical JJ cord-310304-f28tjmi8 45 38 disease disease NN cord-310304-f28tjmi8 45 39 ( ( -LRB- cord-310304-f28tjmi8 45 40 Figure figure NN cord-310304-f28tjmi8 45 41 1 1 CD cord-310304-f28tjmi8 45 42 ) ) -RRB- cord-310304-f28tjmi8 45 43 . . . cord-310304-f28tjmi8 46 1 The the DT cord-310304-f28tjmi8 46 2 use use NN cord-310304-f28tjmi8 46 3 of of IN cord-310304-f28tjmi8 46 4 corticosteroid corticosteroid NN cord-310304-f28tjmi8 46 5 therapy therapy NN cord-310304-f28tjmi8 46 6 to to TO cord-310304-f28tjmi8 46 7 combat combat VB cord-310304-f28tjmi8 46 8 inflammation inflammation NN cord-310304-f28tjmi8 46 9 in in IN cord-310304-f28tjmi8 46 10 COVID-19 covid-19 JJ cord-310304-f28tjmi8 46 11 patients patient NNS cord-310304-f28tjmi8 46 12 also also RB cord-310304-f28tjmi8 46 13 may may MD cord-310304-f28tjmi8 46 14 increase increase VB cord-310304-f28tjmi8 46 15 glucose glucose NN cord-310304-f28tjmi8 46 16 levels level NNS cord-310304-f28tjmi8 46 17 in in IN cord-310304-f28tjmi8 46 18 80 80 CD cord-310304-f28tjmi8 46 19 % % NN cord-310304-f28tjmi8 46 20 of of IN cord-310304-f28tjmi8 46 21 patients patient NNS cord-310304-f28tjmi8 46 22 with with IN cord-310304-f28tjmi8 46 23 diabetes diabete NNS cord-310304-f28tjmi8 46 24 as as RB cord-310304-f28tjmi8 46 25 well well RB cord-310304-f28tjmi8 46 26 as as IN cord-310304-f28tjmi8 46 27 patients patient NNS cord-310304-f28tjmi8 46 28 without without IN cord-310304-f28tjmi8 46 29 diabetes diabete NNS cord-310304-f28tjmi8 46 30 [ [ -LRB- cord-310304-f28tjmi8 46 31 39 39 CD cord-310304-f28tjmi8 46 32 ] ] -RRB- cord-310304-f28tjmi8 46 33 ( ( -LRB- cord-310304-f28tjmi8 46 34 Figure figure NN cord-310304-f28tjmi8 46 35 1 1 CD cord-310304-f28tjmi8 46 36 ) ) -RRB- cord-310304-f28tjmi8 46 37 . . . cord-310304-f28tjmi8 46 38 . . . cord-310304-f28tjmi8 47 1 Hypothetical hypothetical JJ cord-310304-f28tjmi8 47 2 model model NN cord-310304-f28tjmi8 47 3 of of IN cord-310304-f28tjmi8 47 4 uncontrolled uncontrolled JJ cord-310304-f28tjmi8 47 5 glycemia glycemia NN cord-310304-f28tjmi8 47 6 in in IN cord-310304-f28tjmi8 47 7 diabetic diabetic JJ cord-310304-f28tjmi8 47 8 patients patient NNS cord-310304-f28tjmi8 47 9 and and CC cord-310304-f28tjmi8 47 10 increased increase VBN cord-310304-f28tjmi8 47 11 risk risk NN cord-310304-f28tjmi8 47 12 for for IN cord-310304-f28tjmi8 47 13 complications complication NNS cord-310304-f28tjmi8 47 14 due due JJ cord-310304-f28tjmi8 47 15 to to IN cord-310304-f28tjmi8 47 16 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 47 17 . . . cord-310304-f28tjmi8 48 1 Patients patient NNS cord-310304-f28tjmi8 48 2 who who WP cord-310304-f28tjmi8 48 3 clinically clinically RB cord-310304-f28tjmi8 48 4 present present JJ cord-310304-f28tjmi8 48 5 with with IN cord-310304-f28tjmi8 48 6 normal normal JJ cord-310304-f28tjmi8 48 7 or or CC cord-310304-f28tjmi8 48 8 high high JJ cord-310304-f28tjmi8 48 9 blood blood NN cord-310304-f28tjmi8 48 10 pressure pressure NN cord-310304-f28tjmi8 48 11 may may MD cord-310304-f28tjmi8 48 12 be be VB cord-310304-f28tjmi8 48 13 subject subject JJ cord-310304-f28tjmi8 48 14 to to IN cord-310304-f28tjmi8 48 15 undue undue JJ cord-310304-f28tjmi8 48 16 complications complication NNS cord-310304-f28tjmi8 48 17 related relate VBN cord-310304-f28tjmi8 48 18 to to IN cord-310304-f28tjmi8 48 19 severe severe JJ cord-310304-f28tjmi8 48 20 acute acute JJ cord-310304-f28tjmi8 48 21 respiratory respiratory JJ cord-310304-f28tjmi8 48 22 syndrome syndrome NN cord-310304-f28tjmi8 48 23 coronavirus coronavirus NN cord-310304-f28tjmi8 48 24 2 2 CD cord-310304-f28tjmi8 49 1 ( ( -LRB- cord-310304-f28tjmi8 49 2 SARS SARS NNP cord-310304-f28tjmi8 49 3 - - HYPH cord-310304-f28tjmi8 49 4 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 49 5 ) ) -RRB- cord-310304-f28tjmi8 49 6 infection infection NN cord-310304-f28tjmi8 49 7 . . . cord-310304-f28tjmi8 50 1 This this DT cord-310304-f28tjmi8 50 2 is be VBZ cord-310304-f28tjmi8 50 3 an an DT cord-310304-f28tjmi8 50 4 illustration illustration NN cord-310304-f28tjmi8 50 5 of of IN cord-310304-f28tjmi8 50 6 the the DT cord-310304-f28tjmi8 50 7 pancreas pancrea NNS cord-310304-f28tjmi8 50 8 , , , cord-310304-f28tjmi8 50 9 responsible responsible JJ cord-310304-f28tjmi8 50 10 for for IN cord-310304-f28tjmi8 50 11 insulin insulin NN cord-310304-f28tjmi8 50 12 production production NN cord-310304-f28tjmi8 50 13 and and CC cord-310304-f28tjmi8 50 14 regulation regulation NN cord-310304-f28tjmi8 50 15 and and CC cord-310304-f28tjmi8 50 16 the the DT cord-310304-f28tjmi8 50 17 immediate immediate JJ cord-310304-f28tjmi8 50 18 surrounding surround VBG cord-310304-f28tjmi8 50 19 tissue tissue NN cord-310304-f28tjmi8 50 20 and and CC cord-310304-f28tjmi8 50 21 organs organ NNS cord-310304-f28tjmi8 50 22 . . . cord-310304-f28tjmi8 51 1 Once once IN cord-310304-f28tjmi8 51 2 infected infect VBN cord-310304-f28tjmi8 51 3 with with IN cord-310304-f28tjmi8 51 4 SARS SARS NNP cord-310304-f28tjmi8 51 5 - - : cord-310304-f28tjmi8 51 6 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 51 7 some some DT cord-310304-f28tjmi8 51 8 patients patient NNS cord-310304-f28tjmi8 51 9 will will MD cord-310304-f28tjmi8 51 10 experience experience VB cord-310304-f28tjmi8 51 11 increased increase VBN cord-310304-f28tjmi8 51 12 inflammation inflammation NN cord-310304-f28tjmi8 51 13 in in IN cord-310304-f28tjmi8 51 14 the the DT cord-310304-f28tjmi8 51 15 form form NN cord-310304-f28tjmi8 51 16 of of IN cord-310304-f28tjmi8 51 17 a a DT cord-310304-f28tjmi8 51 18 cytokine cytokine NN cord-310304-f28tjmi8 51 19 storm storm NN cord-310304-f28tjmi8 51 20 . . . cord-310304-f28tjmi8 52 1 Corticosteroids corticosteroid NNS cord-310304-f28tjmi8 52 2 often often RB cord-310304-f28tjmi8 52 3 are be VBP cord-310304-f28tjmi8 52 4 Hypothetical hypothetical JJ cord-310304-f28tjmi8 52 5 model model NN cord-310304-f28tjmi8 52 6 of of IN cord-310304-f28tjmi8 52 7 uncontrolled uncontrolled JJ cord-310304-f28tjmi8 52 8 glycemia glycemia NN cord-310304-f28tjmi8 52 9 in in IN cord-310304-f28tjmi8 52 10 diabetic diabetic JJ cord-310304-f28tjmi8 52 11 patients patient NNS cord-310304-f28tjmi8 52 12 and and CC cord-310304-f28tjmi8 52 13 increased increase VBN cord-310304-f28tjmi8 52 14 risk risk NN cord-310304-f28tjmi8 52 15 for for IN cord-310304-f28tjmi8 52 16 complications complication NNS cord-310304-f28tjmi8 52 17 due due JJ cord-310304-f28tjmi8 52 18 to to IN cord-310304-f28tjmi8 52 19 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 52 20 . . . cord-310304-f28tjmi8 53 1 Patients patient NNS cord-310304-f28tjmi8 53 2 who who WP cord-310304-f28tjmi8 53 3 clinically clinically RB cord-310304-f28tjmi8 53 4 present present JJ cord-310304-f28tjmi8 53 5 with with IN cord-310304-f28tjmi8 53 6 normal normal JJ cord-310304-f28tjmi8 53 7 or or CC cord-310304-f28tjmi8 53 8 high high JJ cord-310304-f28tjmi8 53 9 blood blood NN cord-310304-f28tjmi8 53 10 pressure pressure NN cord-310304-f28tjmi8 53 11 may may MD cord-310304-f28tjmi8 53 12 be be VB cord-310304-f28tjmi8 53 13 subject subject JJ cord-310304-f28tjmi8 53 14 to to IN cord-310304-f28tjmi8 53 15 undue undue JJ cord-310304-f28tjmi8 53 16 complications complication NNS cord-310304-f28tjmi8 53 17 related relate VBN cord-310304-f28tjmi8 53 18 to to IN cord-310304-f28tjmi8 53 19 severe severe JJ cord-310304-f28tjmi8 53 20 acute acute JJ cord-310304-f28tjmi8 53 21 respiratory respiratory JJ cord-310304-f28tjmi8 53 22 syndrome syndrome NN cord-310304-f28tjmi8 53 23 coronavirus coronavirus NN cord-310304-f28tjmi8 53 24 2 2 CD cord-310304-f28tjmi8 54 1 ( ( -LRB- cord-310304-f28tjmi8 54 2 SARS SARS NNP cord-310304-f28tjmi8 54 3 - - HYPH cord-310304-f28tjmi8 54 4 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 54 5 ) ) -RRB- cord-310304-f28tjmi8 54 6 infection infection NN cord-310304-f28tjmi8 54 7 . . . cord-310304-f28tjmi8 55 1 This this DT cord-310304-f28tjmi8 55 2 is be VBZ cord-310304-f28tjmi8 55 3 an an DT cord-310304-f28tjmi8 55 4 illustration illustration NN cord-310304-f28tjmi8 55 5 of of IN cord-310304-f28tjmi8 55 6 the the DT cord-310304-f28tjmi8 55 7 pancreas pancrea NNS cord-310304-f28tjmi8 55 8 , , , cord-310304-f28tjmi8 55 9 responsible responsible JJ cord-310304-f28tjmi8 55 10 for for IN cord-310304-f28tjmi8 55 11 insulin insulin NN cord-310304-f28tjmi8 55 12 production production NN cord-310304-f28tjmi8 55 13 and and CC cord-310304-f28tjmi8 55 14 regulation regulation NN cord-310304-f28tjmi8 55 15 and and CC cord-310304-f28tjmi8 55 16 the the DT cord-310304-f28tjmi8 55 17 immediate immediate JJ cord-310304-f28tjmi8 55 18 surrounding surround VBG cord-310304-f28tjmi8 55 19 tissue tissue NN cord-310304-f28tjmi8 55 20 and and CC cord-310304-f28tjmi8 55 21 organs organ NNS cord-310304-f28tjmi8 55 22 . . . cord-310304-f28tjmi8 56 1 Once once IN cord-310304-f28tjmi8 56 2 infected infect VBN cord-310304-f28tjmi8 56 3 with with IN cord-310304-f28tjmi8 56 4 SARS SARS NNP cord-310304-f28tjmi8 56 5 - - : cord-310304-f28tjmi8 56 6 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 56 7 some some DT cord-310304-f28tjmi8 56 8 patients patient NNS cord-310304-f28tjmi8 56 9 will will MD cord-310304-f28tjmi8 56 10 experience experience VB cord-310304-f28tjmi8 56 11 increased increase VBN cord-310304-f28tjmi8 56 12 inflammation inflammation NN cord-310304-f28tjmi8 56 13 in in IN cord-310304-f28tjmi8 56 14 the the DT cord-310304-f28tjmi8 56 15 form form NN cord-310304-f28tjmi8 56 16 of of IN cord-310304-f28tjmi8 56 17 a a DT cord-310304-f28tjmi8 56 18 cytokine cytokine NN cord-310304-f28tjmi8 56 19 storm storm NN cord-310304-f28tjmi8 56 20 . . . cord-310304-f28tjmi8 57 1 Corticosteroids corticosteroid NNS cord-310304-f28tjmi8 57 2 often often RB cord-310304-f28tjmi8 57 3 are be VBP cord-310304-f28tjmi8 57 4 prescribed prescribe VBN cord-310304-f28tjmi8 57 5 to to TO cord-310304-f28tjmi8 57 6 suppress suppress VB cord-310304-f28tjmi8 57 7 inflammation inflammation NN cord-310304-f28tjmi8 57 8 but but CC cord-310304-f28tjmi8 57 9 also also RB cord-310304-f28tjmi8 57 10 are be VBP cord-310304-f28tjmi8 57 11 known know VBN cord-310304-f28tjmi8 57 12 to to TO cord-310304-f28tjmi8 57 13 induce induce VB cord-310304-f28tjmi8 57 14 high high JJ cord-310304-f28tjmi8 57 15 glucose glucose NN cord-310304-f28tjmi8 57 16 levels level NNS cord-310304-f28tjmi8 57 17 in in IN cord-310304-f28tjmi8 57 18 the the DT cord-310304-f28tjmi8 57 19 blood blood NN cord-310304-f28tjmi8 57 20 of of IN cord-310304-f28tjmi8 57 21 both both CC cord-310304-f28tjmi8 57 22 hypoglycemic hypoglycemic JJ cord-310304-f28tjmi8 57 23 and and CC cord-310304-f28tjmi8 57 24 hyperglycemic hyperglycemic JJ cord-310304-f28tjmi8 57 25 patients patient NNS cord-310304-f28tjmi8 57 26 . . . cord-310304-f28tjmi8 58 1 High high JJ cord-310304-f28tjmi8 58 2 blood blood NN cord-310304-f28tjmi8 58 3 glucose glucose NN cord-310304-f28tjmi8 58 4 levels level NNS cord-310304-f28tjmi8 58 5 have have VBP cord-310304-f28tjmi8 58 6 been be VBN cord-310304-f28tjmi8 58 7 implicated implicate VBN cord-310304-f28tjmi8 58 8 in in IN cord-310304-f28tjmi8 58 9 pulmonary pulmonary JJ cord-310304-f28tjmi8 58 10 injury injury NN cord-310304-f28tjmi8 58 11 and and CC cord-310304-f28tjmi8 58 12 may may MD cord-310304-f28tjmi8 58 13 affect affect VB cord-310304-f28tjmi8 58 14 the the DT cord-310304-f28tjmi8 58 15 immune immune JJ cord-310304-f28tjmi8 58 16 response response NN cord-310304-f28tjmi8 58 17 , , , cord-310304-f28tjmi8 58 18 resulting result VBG cord-310304-f28tjmi8 58 19 in in IN cord-310304-f28tjmi8 58 20 poor poor JJ cord-310304-f28tjmi8 58 21 or or CC cord-310304-f28tjmi8 58 22 delayed delay VBN cord-310304-f28tjmi8 58 23 viral viral JJ cord-310304-f28tjmi8 58 24 clearance clearance NN cord-310304-f28tjmi8 58 25 . . . cord-310304-f28tjmi8 59 1 The the DT cord-310304-f28tjmi8 59 2 degree degree NN cord-310304-f28tjmi8 59 3 of of IN cord-310304-f28tjmi8 59 4 lung lung NN cord-310304-f28tjmi8 59 5 injury injury NN cord-310304-f28tjmi8 59 6 will will MD cord-310304-f28tjmi8 59 7 include include VB cord-310304-f28tjmi8 59 8 Angiotensin Angiotensin NNP cord-310304-f28tjmi8 59 9 - - HYPH cord-310304-f28tjmi8 59 10 converting convert VBG cord-310304-f28tjmi8 59 11 enzyme enzyme NN cord-310304-f28tjmi8 59 12 2 2 CD cord-310304-f28tjmi8 59 13 ( ( -LRB- cord-310304-f28tjmi8 59 14 ACE2)-mediated ace2)-mediated CD cord-310304-f28tjmi8 59 15 infection infection NN cord-310304-f28tjmi8 59 16 by by IN cord-310304-f28tjmi8 59 17 SARS SARS NNP cord-310304-f28tjmi8 59 18 - - HYPH cord-310304-f28tjmi8 59 19 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 59 20 that that WDT cord-310304-f28tjmi8 59 21 leads lead VBZ cord-310304-f28tjmi8 59 22 to to IN cord-310304-f28tjmi8 59 23 hypoxia hypoxia NN cord-310304-f28tjmi8 59 24 , , , cord-310304-f28tjmi8 59 25 vascular vascular JJ cord-310304-f28tjmi8 59 26 leakage leakage NN cord-310304-f28tjmi8 59 27 , , , cord-310304-f28tjmi8 59 28 and and CC cord-310304-f28tjmi8 59 29 potentially potentially RB cord-310304-f28tjmi8 59 30 fatal fatal JJ cord-310304-f28tjmi8 59 31 pneumonia pneumonia NN cord-310304-f28tjmi8 59 32 . . . cord-310304-f28tjmi8 60 1 TCR TCR NNP cord-310304-f28tjmi8 60 2 ( ( -LRB- cord-310304-f28tjmi8 60 3 T t NN cord-310304-f28tjmi8 60 4 - - HYPH cord-310304-f28tjmi8 60 5 cell cell NN cord-310304-f28tjmi8 60 6 receptor receptor NN cord-310304-f28tjmi8 60 7 ) ) -RRB- cord-310304-f28tjmi8 60 8 , , , cord-310304-f28tjmi8 60 9 CD4 CD4 NNP cord-310304-f28tjmi8 60 10 ( ( -LRB- cord-310304-f28tjmi8 60 11 cluster cluster NN cord-310304-f28tjmi8 60 12 designation designation NN cord-310304-f28tjmi8 60 13 4 4 CD cord-310304-f28tjmi8 60 14 ) ) -RRB- cord-310304-f28tjmi8 60 15 , , , cord-310304-f28tjmi8 60 16 MHC MHC NNP cord-310304-f28tjmi8 60 17 ( ( -LRB- cord-310304-f28tjmi8 60 18 Major Major NNP cord-310304-f28tjmi8 60 19 Histocompatibility Histocompatibility NNP cord-310304-f28tjmi8 60 20 ) ) -RRB- cord-310304-f28tjmi8 60 21 . . . cord-310304-f28tjmi8 61 1 Adapted adapt VBN cord-310304-f28tjmi8 61 2 from from IN cord-310304-f28tjmi8 61 3 Fraussen Fraussen NNP cord-310304-f28tjmi8 61 4 J J NNP cord-310304-f28tjmi8 61 5 et et NNP cord-310304-f28tjmi8 61 6 al al NNP cord-310304-f28tjmi8 61 7 . . . cord-310304-f28tjmi8 62 1 [ [ -LRB- cord-310304-f28tjmi8 62 2 40 40 CD cord-310304-f28tjmi8 62 3 ] ] -RRB- cord-310304-f28tjmi8 62 4 . . . cord-310304-f28tjmi8 63 1 The the DT cord-310304-f28tjmi8 63 2 WHO who WP cord-310304-f28tjmi8 63 3 concludes conclude VBZ cord-310304-f28tjmi8 63 4 that that IN cord-310304-f28tjmi8 63 5 hypertension hypertension NN cord-310304-f28tjmi8 63 6 is be VBZ cord-310304-f28tjmi8 63 7 the the DT cord-310304-f28tjmi8 63 8 most most RBS cord-310304-f28tjmi8 63 9 important important JJ cord-310304-f28tjmi8 63 10 risk risk NN cord-310304-f28tjmi8 63 11 factor factor NN cord-310304-f28tjmi8 63 12 for for IN cord-310304-f28tjmi8 63 13 death death NN cord-310304-f28tjmi8 63 14 and and CC cord-310304-f28tjmi8 63 15 disability disability NN cord-310304-f28tjmi8 63 16 worldwide worldwide RB cord-310304-f28tjmi8 63 17 , , , cord-310304-f28tjmi8 63 18 affecting affect VBG cord-310304-f28tjmi8 63 19 more more JJR cord-310304-f28tjmi8 63 20 than than IN cord-310304-f28tjmi8 63 21 1 1 CD cord-310304-f28tjmi8 63 22 billion billion CD cord-310304-f28tjmi8 63 23 people people NNS cord-310304-f28tjmi8 63 24 and and CC cord-310304-f28tjmi8 63 25 causing cause VBG cord-310304-f28tjmi8 63 26 an an DT cord-310304-f28tjmi8 63 27 estimated estimate VBN cord-310304-f28tjmi8 63 28 9.4 9.4 CD cord-310304-f28tjmi8 63 29 million million CD cord-310304-f28tjmi8 63 30 deaths death NNS cord-310304-f28tjmi8 63 31 annually annually RB cord-310304-f28tjmi8 63 32 [ [ -LRB- cord-310304-f28tjmi8 63 33 41 41 CD cord-310304-f28tjmi8 63 34 ] ] -RRB- cord-310304-f28tjmi8 63 35 . . . cord-310304-f28tjmi8 64 1 AA AA NNP cord-310304-f28tjmi8 64 2 adults adult NNS cord-310304-f28tjmi8 64 3 have have VBP cord-310304-f28tjmi8 64 4 the the DT cord-310304-f28tjmi8 64 5 highest high JJS cord-310304-f28tjmi8 64 6 prevalence prevalence NN cord-310304-f28tjmi8 64 7 of of IN cord-310304-f28tjmi8 64 8 hypertension hypertension NN cord-310304-f28tjmi8 64 9 in in IN cord-310304-f28tjmi8 64 10 the the DT cord-310304-f28tjmi8 64 11 US US NNP cord-310304-f28tjmi8 64 12 , , , cord-310304-f28tjmi8 64 13 affecting affect VBG cord-310304-f28tjmi8 64 14 40.8 40.8 CD cord-310304-f28tjmi8 64 15 % % NN cord-310304-f28tjmi8 64 16 of of IN cord-310304-f28tjmi8 64 17 men man NNS cord-310304-f28tjmi8 64 18 and and CC cord-310304-f28tjmi8 64 19 41.5 41.5 CD cord-310304-f28tjmi8 64 20 % % NN cord-310304-f28tjmi8 64 21 of of IN cord-310304-f28tjmi8 64 22 women woman NNS cord-310304-f28tjmi8 64 23 , , , cord-310304-f28tjmi8 64 24 in in IN cord-310304-f28tjmi8 64 25 contrast contrast NN cord-310304-f28tjmi8 64 26 to to IN cord-310304-f28tjmi8 64 27 significantly significantly RB cord-310304-f28tjmi8 64 28 lower low JJR cord-310304-f28tjmi8 64 29 rates rate NNS cord-310304-f28tjmi8 64 30 in in IN cord-310304-f28tjmi8 64 31 NHW NHW NNP cord-310304-f28tjmi8 64 32 , , , cord-310304-f28tjmi8 64 33 non non JJ cord-310304-f28tjmi8 64 34 - - JJ cord-310304-f28tjmi8 64 35 Hispanic hispanic JJ cord-310304-f28tjmi8 64 36 Asian asian JJ cord-310304-f28tjmi8 64 37 ( ( -LRB- cord-310304-f28tjmi8 64 38 NHA NHA NNP cord-310304-f28tjmi8 64 39 ) ) -RRB- cord-310304-f28tjmi8 64 40 , , , cord-310304-f28tjmi8 64 41 and and CC cord-310304-f28tjmi8 64 42 H H NNP cord-310304-f28tjmi8 64 43 / / SYM cord-310304-f28tjmi8 64 44 L L NNP cord-310304-f28tjmi8 64 45 men man NNS cord-310304-f28tjmi8 64 46 and and CC cord-310304-f28tjmi8 64 47 women woman NNS cord-310304-f28tjmi8 64 48 [ [ -LRB- cord-310304-f28tjmi8 64 49 42 42 CD cord-310304-f28tjmi8 64 50 ] ] -RRB- cord-310304-f28tjmi8 64 51 . . . cord-310304-f28tjmi8 65 1 Hypertension hypertension NN cord-310304-f28tjmi8 65 2 is be VBZ cord-310304-f28tjmi8 65 3 the the DT cord-310304-f28tjmi8 65 4 most most RBS cord-310304-f28tjmi8 65 5 significant significant JJ cord-310304-f28tjmi8 65 6 factor factor NN cord-310304-f28tjmi8 65 7 that that WDT cord-310304-f28tjmi8 65 8 directly directly RB cord-310304-f28tjmi8 65 9 contributes contribute VBZ cord-310304-f28tjmi8 65 10 to to IN cord-310304-f28tjmi8 65 11 disparities disparity NNS cord-310304-f28tjmi8 65 12 in in IN cord-310304-f28tjmi8 65 13 CVD CVD NNP cord-310304-f28tjmi8 65 14 and and CC cord-310304-f28tjmi8 65 15 renal renal JJ cord-310304-f28tjmi8 65 16 disease disease NN cord-310304-f28tjmi8 65 17 among among IN cord-310304-f28tjmi8 65 18 AAs aas NN cord-310304-f28tjmi8 65 19 compared compare VBN cord-310304-f28tjmi8 65 20 with with IN cord-310304-f28tjmi8 65 21 NHWs nhws NN cord-310304-f28tjmi8 65 22 [ [ -LRB- cord-310304-f28tjmi8 65 23 42 42 CD cord-310304-f28tjmi8 65 24 ] ] -RRB- cord-310304-f28tjmi8 65 25 . . . cord-310304-f28tjmi8 66 1 In in IN cord-310304-f28tjmi8 66 2 a a DT cord-310304-f28tjmi8 66 3 study study NN cord-310304-f28tjmi8 66 4 by by IN cord-310304-f28tjmi8 66 5 Zhou Zhou NNP cord-310304-f28tjmi8 66 6 et et NNP cord-310304-f28tjmi8 66 7 al al NNP cord-310304-f28tjmi8 66 8 . . . cord-310304-f28tjmi8 67 1 , , , cord-310304-f28tjmi8 67 2 the the DT cord-310304-f28tjmi8 67 3 most most RBS cord-310304-f28tjmi8 67 4 common common JJ cord-310304-f28tjmi8 67 5 comorbidities comorbiditie NNS cord-310304-f28tjmi8 67 6 associated associate VBN cord-310304-f28tjmi8 67 7 with with IN cord-310304-f28tjmi8 67 8 adverse adverse JJ cord-310304-f28tjmi8 67 9 clinical clinical JJ cord-310304-f28tjmi8 67 10 outcomes outcome NNS cord-310304-f28tjmi8 67 11 in in IN cord-310304-f28tjmi8 67 12 COVID-19 covid-19 JJ cord-310304-f28tjmi8 67 13 patients patient NNS cord-310304-f28tjmi8 67 14 were be VBD cord-310304-f28tjmi8 67 15 hypertension hypertension NN cord-310304-f28tjmi8 67 16 ( ( -LRB- cord-310304-f28tjmi8 67 17 30 30 CD cord-310304-f28tjmi8 67 18 % % NN cord-310304-f28tjmi8 67 19 ) ) -RRB- cord-310304-f28tjmi8 67 20 , , , cord-310304-f28tjmi8 67 21 diabetes diabetes NN cord-310304-f28tjmi8 67 22 ( ( -LRB- cord-310304-f28tjmi8 67 23 19 19 CD cord-310304-f28tjmi8 67 24 % % NN cord-310304-f28tjmi8 67 25 ) ) -RRB- cord-310304-f28tjmi8 67 26 , , , cord-310304-f28tjmi8 67 27 and and CC cord-310304-f28tjmi8 67 28 coronary coronary JJ cord-310304-f28tjmi8 67 29 heart heart NN cord-310304-f28tjmi8 67 30 disease disease NN cord-310304-f28tjmi8 67 31 ( ( -LRB- cord-310304-f28tjmi8 67 32 8 8 CD cord-310304-f28tjmi8 67 33 % % NN cord-310304-f28tjmi8 67 34 ) ) -RRB- cord-310304-f28tjmi8 68 1 [ [ -LRB- cord-310304-f28tjmi8 68 2 43 43 CD cord-310304-f28tjmi8 68 3 ] ] -RRB- cord-310304-f28tjmi8 68 4 . . . cord-310304-f28tjmi8 69 1 In in IN cord-310304-f28tjmi8 69 2 a a DT cord-310304-f28tjmi8 69 3 separate separate JJ cord-310304-f28tjmi8 69 4 study study NN cord-310304-f28tjmi8 69 5 by by IN cord-310304-f28tjmi8 69 6 Wu Wu NNP cord-310304-f28tjmi8 69 7 , , , cord-310304-f28tjmi8 69 8 the the DT cord-310304-f28tjmi8 69 9 most most RBS cord-310304-f28tjmi8 69 10 common common JJ cord-310304-f28tjmi8 69 11 comorbidities comorbiditie NNS cord-310304-f28tjmi8 69 12 associated associate VBN cord-310304-f28tjmi8 69 13 with with IN cord-310304-f28tjmi8 69 14 COVID-19 covid-19 JJ cord-310304-f28tjmi8 69 15 patients patient NNS cord-310304-f28tjmi8 69 16 who who WP cord-310304-f28tjmi8 69 17 developed develop VBD cord-310304-f28tjmi8 69 18 acute acute JJ cord-310304-f28tjmi8 69 19 respiratory respiratory JJ cord-310304-f28tjmi8 69 20 distress distress NN cord-310304-f28tjmi8 69 21 syndrome syndrome NN cord-310304-f28tjmi8 69 22 were be VBD cord-310304-f28tjmi8 69 23 hypertension hypertension NN cord-310304-f28tjmi8 69 24 ( ( -LRB- cord-310304-f28tjmi8 69 25 27 27 CD cord-310304-f28tjmi8 69 26 % % NN cord-310304-f28tjmi8 69 27 ) ) -RRB- cord-310304-f28tjmi8 69 28 , , , cord-310304-f28tjmi8 69 29 diabetes diabetes NN cord-310304-f28tjmi8 69 30 ( ( -LRB- cord-310304-f28tjmi8 69 31 19 19 CD cord-310304-f28tjmi8 69 32 % % NN cord-310304-f28tjmi8 69 33 ) ) -RRB- cord-310304-f28tjmi8 69 34 , , , cord-310304-f28tjmi8 69 35 and and CC cord-310304-f28tjmi8 69 36 CVD CVD NNP cord-310304-f28tjmi8 69 37 ( ( -LRB- cord-310304-f28tjmi8 69 38 6 6 CD cord-310304-f28tjmi8 69 39 % % NN cord-310304-f28tjmi8 69 40 ) ) -RRB- cord-310304-f28tjmi8 69 41 [ [ -LRB- cord-310304-f28tjmi8 69 42 44 44 CD cord-310304-f28tjmi8 69 43 ] ] -RRB- cord-310304-f28tjmi8 69 44 . . . cord-310304-f28tjmi8 70 1 In in IN cord-310304-f28tjmi8 70 2 these these DT cord-310304-f28tjmi8 70 3 two two CD cord-310304-f28tjmi8 70 4 major major JJ cord-310304-f28tjmi8 70 5 studies study NNS cord-310304-f28tjmi8 70 6 , , , cord-310304-f28tjmi8 70 7 hypertension hypertension NN cord-310304-f28tjmi8 70 8 was be VBD cord-310304-f28tjmi8 70 9 found find VBN cord-310304-f28tjmi8 70 10 to to TO cord-310304-f28tjmi8 70 11 be be VB cord-310304-f28tjmi8 70 12 the the DT cord-310304-f28tjmi8 70 13 most most RBS cord-310304-f28tjmi8 70 14 significant significant JJ cord-310304-f28tjmi8 70 15 comorbidity comorbidity NN cord-310304-f28tjmi8 70 16 associated associate VBN cord-310304-f28tjmi8 70 17 with with IN cord-310304-f28tjmi8 70 18 the the DT cord-310304-f28tjmi8 70 19 most most RBS cord-310304-f28tjmi8 70 20 severe severe JJ cord-310304-f28tjmi8 70 21 complications complication NNS cord-310304-f28tjmi8 70 22 from from IN cord-310304-f28tjmi8 70 23 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 70 24 . . . cord-310304-f28tjmi8 71 1 Hypertension hypertension NN cord-310304-f28tjmi8 71 2 is be VBZ cord-310304-f28tjmi8 71 3 not not RB cord-310304-f28tjmi8 71 4 known know VBN cord-310304-f28tjmi8 71 5 to to TO cord-310304-f28tjmi8 71 6 be be VB cord-310304-f28tjmi8 71 7 causative causative JJ cord-310304-f28tjmi8 71 8 in in IN cord-310304-f28tjmi8 71 9 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 71 10 pathobiology pathobiology NN cord-310304-f28tjmi8 71 11 , , , cord-310304-f28tjmi8 71 12 and and CC cord-310304-f28tjmi8 71 13 elderly elderly JJ cord-310304-f28tjmi8 71 14 patients patient NNS cord-310304-f28tjmi8 71 15 are be VBP cord-310304-f28tjmi8 71 16 more more RBR cord-310304-f28tjmi8 71 17 likely likely JJ cord-310304-f28tjmi8 71 18 to to TO cord-310304-f28tjmi8 71 19 be be VB cord-310304-f28tjmi8 71 20 hypertensive hypertensive JJ cord-310304-f28tjmi8 71 21 and and CC cord-310304-f28tjmi8 71 22 are be VBP cord-310304-f28tjmi8 71 23 known know VBN cord-310304-f28tjmi8 71 24 to to TO cord-310304-f28tjmi8 71 25 be be VB cord-310304-f28tjmi8 71 26 at at IN cord-310304-f28tjmi8 71 27 greater great JJR cord-310304-f28tjmi8 71 28 risk risk NN cord-310304-f28tjmi8 71 29 of of IN cord-310304-f28tjmi8 71 30 severe severe JJ cord-310304-f28tjmi8 71 31 disease disease NN cord-310304-f28tjmi8 71 32 . . . cord-310304-f28tjmi8 72 1 It -PRON- PRP cord-310304-f28tjmi8 72 2 also also RB cord-310304-f28tjmi8 72 3 remains remain VBZ cord-310304-f28tjmi8 72 4 unclear unclear JJ cord-310304-f28tjmi8 72 5 whether whether IN cord-310304-f28tjmi8 72 6 medications medication NNS cord-310304-f28tjmi8 72 7 used use VBN cord-310304-f28tjmi8 72 8 to to TO cord-310304-f28tjmi8 72 9 treat treat VB cord-310304-f28tjmi8 72 10 hypertension hypertension NN cord-310304-f28tjmi8 72 11 , , , cord-310304-f28tjmi8 72 12 such such JJ cord-310304-f28tjmi8 72 13 Angiotensin Angiotensin NNP cord-310304-f28tjmi8 72 14 - - HYPH cord-310304-f28tjmi8 72 15 converting convert VBG cord-310304-f28tjmi8 72 16 enzyme enzyme NN cord-310304-f28tjmi8 72 17 inhibitors inhibitor NNS cord-310304-f28tjmi8 72 18 ( ( -LRB- cord-310304-f28tjmi8 72 19 ACEIs acei NNS cord-310304-f28tjmi8 72 20 ) ) -RRB- cord-310304-f28tjmi8 72 21 , , , cord-310304-f28tjmi8 72 22 have have VBP cord-310304-f28tjmi8 72 23 a a DT cord-310304-f28tjmi8 72 24 role role NN cord-310304-f28tjmi8 72 25 in in IN cord-310304-f28tjmi8 72 26 acquisition acquisition NN cord-310304-f28tjmi8 72 27 or or CC cord-310304-f28tjmi8 72 28 progressive progressive JJ cord-310304-f28tjmi8 72 29 development development NN cord-310304-f28tjmi8 72 30 of of IN cord-310304-f28tjmi8 72 31 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 72 32 in in IN cord-310304-f28tjmi8 72 33 patients patient NNS cord-310304-f28tjmi8 72 34 . . . cord-310304-f28tjmi8 73 1 In in IN cord-310304-f28tjmi8 73 2 humans human NNS cord-310304-f28tjmi8 73 3 , , , cord-310304-f28tjmi8 73 4 the the DT cord-310304-f28tjmi8 73 5 liver liver NN cord-310304-f28tjmi8 73 6 produces produce VBZ cord-310304-f28tjmi8 73 7 angiotensinogen angiotensinogen NNP cord-310304-f28tjmi8 73 8 , , , cord-310304-f28tjmi8 73 9 which which WDT cord-310304-f28tjmi8 73 10 is be VBZ cord-310304-f28tjmi8 73 11 converted convert VBN cord-310304-f28tjmi8 73 12 to to IN cord-310304-f28tjmi8 73 13 angiotensin angiotensin NN cord-310304-f28tjmi8 73 14 I -PRON- PRP cord-310304-f28tjmi8 73 15 by by IN cord-310304-f28tjmi8 73 16 renin renin NN cord-310304-f28tjmi8 73 17 from from IN cord-310304-f28tjmi8 73 18 the the DT cord-310304-f28tjmi8 73 19 kidneys kidney NNS cord-310304-f28tjmi8 73 20 , , , cord-310304-f28tjmi8 73 21 and and CC cord-310304-f28tjmi8 73 22 angiotensin angiotensin NN cord-310304-f28tjmi8 73 23 I -PRON- PRP cord-310304-f28tjmi8 73 24 is be VBZ cord-310304-f28tjmi8 73 25 converted convert VBN cord-310304-f28tjmi8 73 26 to to IN cord-310304-f28tjmi8 73 27 angiotensin angiotensin NN cord-310304-f28tjmi8 73 28 II II NNP cord-310304-f28tjmi8 73 29 by by IN cord-310304-f28tjmi8 73 30 the the DT cord-310304-f28tjmi8 73 31 action action NN cord-310304-f28tjmi8 73 32 of of IN cord-310304-f28tjmi8 73 33 ACE ACE NNP cord-310304-f28tjmi8 73 34 ( ( -LRB- cord-310304-f28tjmi8 73 35 Figure figure NN cord-310304-f28tjmi8 73 36 2 2 CD cord-310304-f28tjmi8 73 37 ) ) -RRB- cord-310304-f28tjmi8 73 38 . . . cord-310304-f28tjmi8 74 1 Normally normally RB cord-310304-f28tjmi8 74 2 , , , cord-310304-f28tjmi8 74 3 angiotensin angiotensin NN cord-310304-f28tjmi8 74 4 II II NNP cord-310304-f28tjmi8 74 5 is be VBZ cord-310304-f28tjmi8 74 6 converted convert VBN cord-310304-f28tjmi8 74 7 to to IN cord-310304-f28tjmi8 74 8 angiotensin-1 angiotensin-1 NNP cord-310304-f28tjmi8 74 9 - - HYPH cord-310304-f28tjmi8 74 10 7 7 CD cord-310304-f28tjmi8 74 11 by by IN cord-310304-f28tjmi8 74 12 the the DT cord-310304-f28tjmi8 74 13 monocarboxypetidase monocarboxypetidase NNP cord-310304-f28tjmi8 74 14 ACE2 ACE2 NNP cord-310304-f28tjmi8 74 15 ( ( -LRB- cord-310304-f28tjmi8 74 16 Figure figure NN cord-310304-f28tjmi8 74 17 2 2 CD cord-310304-f28tjmi8 74 18 ) ) -RRB- cord-310304-f28tjmi8 74 19 . . . cord-310304-f28tjmi8 75 1 However however RB cord-310304-f28tjmi8 75 2 , , , cord-310304-f28tjmi8 75 3 upon upon IN cord-310304-f28tjmi8 75 4 infection infection NN cord-310304-f28tjmi8 75 5 with with IN cord-310304-f28tjmi8 75 6 SARS SARS NNP cord-310304-f28tjmi8 75 7 - - HYPH cord-310304-f28tjmi8 75 8 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 75 9 , , , cord-310304-f28tjmi8 75 10 the the DT cord-310304-f28tjmi8 75 11 ACE2 ACE2 NNP cord-310304-f28tjmi8 75 12 protein protein NN cord-310304-f28tjmi8 75 13 serves serve VBZ cord-310304-f28tjmi8 75 14 as as IN cord-310304-f28tjmi8 75 15 an an DT cord-310304-f28tjmi8 75 16 entry entry NN cord-310304-f28tjmi8 75 17 receptor receptor NN cord-310304-f28tjmi8 75 18 for for IN cord-310304-f28tjmi8 75 19 the the DT cord-310304-f28tjmi8 75 20 virus virus NN cord-310304-f28tjmi8 75 21 and and CC cord-310304-f28tjmi8 75 22 is be VBZ cord-310304-f28tjmi8 75 23 internalized internalize VBN cord-310304-f28tjmi8 75 24 with with IN cord-310304-f28tjmi8 75 25 SARS SARS NNP cord-310304-f28tjmi8 75 26 - - HYPH cord-310304-f28tjmi8 75 27 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 75 28 during during IN cord-310304-f28tjmi8 75 29 membrane membrane NN cord-310304-f28tjmi8 75 30 fusion fusion NN cord-310304-f28tjmi8 75 31 and and CC cord-310304-f28tjmi8 75 32 uptake uptake NN cord-310304-f28tjmi8 75 33 by by IN cord-310304-f28tjmi8 75 34 infected infected JJ cord-310304-f28tjmi8 75 35 cells cell NNS cord-310304-f28tjmi8 75 36 ( ( -LRB- cord-310304-f28tjmi8 75 37 Figure figure NN cord-310304-f28tjmi8 75 38 2 2 CD cord-310304-f28tjmi8 75 39 ) ) -RRB- cord-310304-f28tjmi8 75 40 . . . cord-310304-f28tjmi8 76 1 This this DT cord-310304-f28tjmi8 76 2 leads lead VBZ cord-310304-f28tjmi8 76 3 to to IN cord-310304-f28tjmi8 76 4 a a DT cord-310304-f28tjmi8 76 5 significant significant JJ cord-310304-f28tjmi8 76 6 reduction reduction NN cord-310304-f28tjmi8 76 7 in in IN cord-310304-f28tjmi8 76 8 ACE2 ACE2 NNP cord-310304-f28tjmi8 76 9 surface surface NN cord-310304-f28tjmi8 76 10 expression expression NN cord-310304-f28tjmi8 76 11 and and CC cord-310304-f28tjmi8 76 12 a a DT cord-310304-f28tjmi8 76 13 concomitant concomitant JJ cord-310304-f28tjmi8 76 14 increase increase NN cord-310304-f28tjmi8 76 15 in in IN cord-310304-f28tjmi8 76 16 angiotensin angiotensin NN cord-310304-f28tjmi8 76 17 II II NNP cord-310304-f28tjmi8 76 18 , , , cord-310304-f28tjmi8 76 19 further further RB cord-310304-f28tjmi8 76 20 leading lead VBG cord-310304-f28tjmi8 76 21 to to IN cord-310304-f28tjmi8 76 22 vasoconstriction vasoconstriction NN cord-310304-f28tjmi8 76 23 that that WDT cord-310304-f28tjmi8 76 24 impacts impact VBZ cord-310304-f28tjmi8 76 25 blood blood NN cord-310304-f28tjmi8 76 26 pressure pressure NN cord-310304-f28tjmi8 76 27 and and CC cord-310304-f28tjmi8 76 28 causes cause VBZ cord-310304-f28tjmi8 76 29 inflammation inflammation NN cord-310304-f28tjmi8 76 30 , , , cord-310304-f28tjmi8 76 31 fibrosis fibrosis NN cord-310304-f28tjmi8 76 32 , , , cord-310304-f28tjmi8 76 33 and and CC cord-310304-f28tjmi8 76 34 oxidative oxidative JJ cord-310304-f28tjmi8 76 35 stress stress NN cord-310304-f28tjmi8 76 36 in in IN cord-310304-f28tjmi8 76 37 infected infected JJ cord-310304-f28tjmi8 76 38 tissues tissue NNS cord-310304-f28tjmi8 76 39 within within IN cord-310304-f28tjmi8 76 40 multiple multiple JJ cord-310304-f28tjmi8 76 41 organs organ NNS cord-310304-f28tjmi8 76 42 ( ( -LRB- cord-310304-f28tjmi8 76 43 Figure figure NN cord-310304-f28tjmi8 76 44 2 2 CD cord-310304-f28tjmi8 76 45 ) ) -RRB- cord-310304-f28tjmi8 76 46 . . . cord-310304-f28tjmi8 77 1 Thus thus RB cord-310304-f28tjmi8 77 2 , , , cord-310304-f28tjmi8 77 3 the the DT cord-310304-f28tjmi8 77 4 downregulation downregulation NN cord-310304-f28tjmi8 77 5 of of IN cord-310304-f28tjmi8 77 6 ACE2 ACE2 NNP cord-310304-f28tjmi8 77 7 leads lead VBZ cord-310304-f28tjmi8 77 8 to to IN cord-310304-f28tjmi8 77 9 the the DT cord-310304-f28tjmi8 77 10 upregulation upregulation NN cord-310304-f28tjmi8 77 11 of of IN cord-310304-f28tjmi8 77 12 aldosterone aldosterone NN cord-310304-f28tjmi8 77 13 , , , cord-310304-f28tjmi8 77 14 which which WDT cord-310304-f28tjmi8 77 15 increases increase VBZ cord-310304-f28tjmi8 77 16 the the DT cord-310304-f28tjmi8 77 17 activity activity NN cord-310304-f28tjmi8 77 18 of of IN cord-310304-f28tjmi8 77 19 ACE1 ACE1 NNP cord-310304-f28tjmi8 77 20 , , , cord-310304-f28tjmi8 77 21 which which WDT cord-310304-f28tjmi8 77 22 again again RB cord-310304-f28tjmi8 77 23 leads lead VBZ cord-310304-f28tjmi8 77 24 to to IN cord-310304-f28tjmi8 77 25 higher high JJR cord-310304-f28tjmi8 77 26 levels level NNS cord-310304-f28tjmi8 77 27 of of IN cord-310304-f28tjmi8 77 28 angiotensin angiotensin NN cord-310304-f28tjmi8 77 29 II II NNP cord-310304-f28tjmi8 77 30 and and CC cord-310304-f28tjmi8 77 31 an an DT cord-310304-f28tjmi8 77 32 overall overall JJ cord-310304-f28tjmi8 77 33 suppression suppression NN cord-310304-f28tjmi8 77 34 of of IN cord-310304-f28tjmi8 77 35 angiotensin-1 angiotensin-1 NNP cord-310304-f28tjmi8 77 36 - - HYPH cord-310304-f28tjmi8 77 37 7 7 CD cord-310304-f28tjmi8 77 38 , , , cord-310304-f28tjmi8 77 39 designed design VBN cord-310304-f28tjmi8 77 40 to to TO cord-310304-f28tjmi8 77 41 mitigate mitigate VB cord-310304-f28tjmi8 77 42 the the DT cord-310304-f28tjmi8 77 43 effects effect NNS cord-310304-f28tjmi8 77 44 of of IN cord-310304-f28tjmi8 77 45 angiotensin angiotensin NN cord-310304-f28tjmi8 77 46 II II NNP cord-310304-f28tjmi8 77 47 via via IN cord-310304-f28tjmi8 77 48 vasodilation vasodilation NN cord-310304-f28tjmi8 77 49 , , , cord-310304-f28tjmi8 77 50 anti anti JJ cord-310304-f28tjmi8 77 51 - - JJ cord-310304-f28tjmi8 77 52 inflammatory inflammatory JJ cord-310304-f28tjmi8 77 53 effects effect NNS cord-310304-f28tjmi8 77 54 , , , cord-310304-f28tjmi8 77 55 and and CC cord-310304-f28tjmi8 77 56 anti anti JJ cord-310304-f28tjmi8 77 57 - - JJ cord-310304-f28tjmi8 77 58 oxidation oxidation JJ cord-310304-f28tjmi8 77 59 ( ( -LRB- cord-310304-f28tjmi8 77 60 Figure figure NN cord-310304-f28tjmi8 77 61 2 2 CD cord-310304-f28tjmi8 77 62 ) ) -RRB- cord-310304-f28tjmi8 77 63 . . . cord-310304-f28tjmi8 78 1 Taken take VBN cord-310304-f28tjmi8 78 2 together together RB cord-310304-f28tjmi8 78 3 , , , cord-310304-f28tjmi8 78 4 this this DT cord-310304-f28tjmi8 78 5 may may MD cord-310304-f28tjmi8 78 6 result result VB cord-310304-f28tjmi8 78 7 in in IN cord-310304-f28tjmi8 78 8 multi multi JJ cord-310304-f28tjmi8 78 9 - - JJ cord-310304-f28tjmi8 78 10 organ organ JJ cord-310304-f28tjmi8 78 11 dysfunction dysfunction NN cord-310304-f28tjmi8 78 12 ( ( -LRB- cord-310304-f28tjmi8 78 13 MOD MOD NNP cord-310304-f28tjmi8 78 14 ) ) -RRB- cord-310304-f28tjmi8 78 15 or or CC cord-310304-f28tjmi8 78 16 failure failure NN cord-310304-f28tjmi8 78 17 . . . cord-310304-f28tjmi8 79 1 However however RB cord-310304-f28tjmi8 79 2 , , , cord-310304-f28tjmi8 79 3 it -PRON- PRP cord-310304-f28tjmi8 79 4 is be VBZ cord-310304-f28tjmi8 79 5 known know VBN cord-310304-f28tjmi8 79 6 that that IN cord-310304-f28tjmi8 79 7 SARS SARS NNP cord-310304-f28tjmi8 79 8 - - HYPH cord-310304-f28tjmi8 79 9 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 79 10 binds bind VBZ cord-310304-f28tjmi8 79 11 to to IN cord-310304-f28tjmi8 79 12 the the DT cord-310304-f28tjmi8 79 13 ACE2 ACE2 NNP cord-310304-f28tjmi8 79 14 receptor receptor NN cord-310304-f28tjmi8 79 15 , , , cord-310304-f28tjmi8 79 16 mainly mainly RB cord-310304-f28tjmi8 79 17 in in IN cord-310304-f28tjmi8 79 18 the the DT cord-310304-f28tjmi8 79 19 lung lung NN cord-310304-f28tjmi8 79 20 , , , cord-310304-f28tjmi8 79 21 to to TO cord-310304-f28tjmi8 79 22 enter enter VB cord-310304-f28tjmi8 79 23 cells cell NNS cord-310304-f28tjmi8 79 24 [ [ -LRB- cord-310304-f28tjmi8 79 25 45 45 CD cord-310304-f28tjmi8 79 26 , , , cord-310304-f28tjmi8 79 27 46 46 CD cord-310304-f28tjmi8 79 28 ] ] -RRB- cord-310304-f28tjmi8 79 29 . . . cord-310304-f28tjmi8 80 1 Therefore therefore RB cord-310304-f28tjmi8 80 2 , , , cord-310304-f28tjmi8 80 3 it -PRON- PRP cord-310304-f28tjmi8 80 4 remains remain VBZ cord-310304-f28tjmi8 80 5 controversial controversial JJ cord-310304-f28tjmi8 80 6 whether whether IN cord-310304-f28tjmi8 80 7 treatment treatment NN cord-310304-f28tjmi8 80 8 of of IN cord-310304-f28tjmi8 80 9 hypertension hypertension NN cord-310304-f28tjmi8 80 10 with with IN cord-310304-f28tjmi8 80 11 ACEIs acei NNS cord-310304-f28tjmi8 80 12 is be VBZ cord-310304-f28tjmi8 80 13 beneficial beneficial JJ cord-310304-f28tjmi8 80 14 or or CC cord-310304-f28tjmi8 80 15 counter counter JJ cord-310304-f28tjmi8 80 16 - - JJ cord-310304-f28tjmi8 80 17 productive productive JJ cord-310304-f28tjmi8 80 18 in in IN cord-310304-f28tjmi8 80 19 COVID-19 covid-19 JJ cord-310304-f28tjmi8 80 20 patients patient NNS cord-310304-f28tjmi8 80 21 . . . cord-310304-f28tjmi8 81 1 Studies study NNS cord-310304-f28tjmi8 81 2 have have VBP cord-310304-f28tjmi8 81 3 shown show VBN cord-310304-f28tjmi8 81 4 the the DT cord-310304-f28tjmi8 81 5 ACEIs acei NNS cord-310304-f28tjmi8 81 6 have have VB cord-310304-f28tjmi8 81 7 a a DT cord-310304-f28tjmi8 81 8 protective protective JJ cord-310304-f28tjmi8 81 9 anti anti JJ cord-310304-f28tjmi8 81 10 - - JJ cord-310304-f28tjmi8 81 11 inflammatory inflammatory JJ cord-310304-f28tjmi8 81 12 effect effect NN cord-310304-f28tjmi8 81 13 in in IN cord-310304-f28tjmi8 81 14 the the DT cord-310304-f28tjmi8 81 15 lung lung NN cord-310304-f28tjmi8 81 16 , , , cord-310304-f28tjmi8 81 17 and and CC cord-310304-f28tjmi8 81 18 soluble soluble JJ cord-310304-f28tjmi8 81 19 ACEIs acei NNS cord-310304-f28tjmi8 81 20 could could MD cord-310304-f28tjmi8 81 21 bind bind VB cord-310304-f28tjmi8 81 22 free free JJ cord-310304-f28tjmi8 81 23 virus virus NN cord-310304-f28tjmi8 81 24 and and CC cord-310304-f28tjmi8 81 25 serve serve VB cord-310304-f28tjmi8 81 26 as as IN cord-310304-f28tjmi8 81 27 therapeutics therapeutic NNS cord-310304-f28tjmi8 81 28 to to TO cord-310304-f28tjmi8 81 29 reduce reduce VB cord-310304-f28tjmi8 81 30 virus virus NN cord-310304-f28tjmi8 81 31 load load NN cord-310304-f28tjmi8 81 32 [ [ -LRB- cord-310304-f28tjmi8 81 33 47 47 CD cord-310304-f28tjmi8 81 34 ] ] -RRB- cord-310304-f28tjmi8 81 35 [ [ -LRB- cord-310304-f28tjmi8 81 36 48 48 CD cord-310304-f28tjmi8 81 37 ] ] -RRB- cord-310304-f28tjmi8 81 38 [ [ -LRB- cord-310304-f28tjmi8 81 39 49 49 CD cord-310304-f28tjmi8 81 40 ] ] -RRB- cord-310304-f28tjmi8 81 41 . . . cord-310304-f28tjmi8 82 1 If if IN cord-310304-f28tjmi8 82 2 corticosteroid corticosteroid NN cord-310304-f28tjmi8 82 3 therapy therapy NN cord-310304-f28tjmi8 82 4 is be VBZ cord-310304-f28tjmi8 82 5 recommended recommend VBN cord-310304-f28tjmi8 82 6 for for IN cord-310304-f28tjmi8 82 7 COVID-19 covid-19 JJ cord-310304-f28tjmi8 82 8 patients patient NNS cord-310304-f28tjmi8 82 9 , , , cord-310304-f28tjmi8 82 10 glucose glucose NN cord-310304-f28tjmi8 82 11 levels level NNS cord-310304-f28tjmi8 82 12 should should MD cord-310304-f28tjmi8 82 13 be be VB cord-310304-f28tjmi8 82 14 monitored monitor VBN cord-310304-f28tjmi8 82 15 carefully carefully RB cord-310304-f28tjmi8 82 16 to to TO cord-310304-f28tjmi8 82 17 avoid avoid VB cord-310304-f28tjmi8 82 18 pulmonary pulmonary JJ cord-310304-f28tjmi8 82 19 and and CC cord-310304-f28tjmi8 82 20 immune immune JJ cord-310304-f28tjmi8 82 21 dysfunction dysfunction NN cord-310304-f28tjmi8 82 22 [ [ -LRB- cord-310304-f28tjmi8 82 23 50 50 CD cord-310304-f28tjmi8 82 24 , , , cord-310304-f28tjmi8 82 25 51 51 CD cord-310304-f28tjmi8 82 26 ] ] -RRB- cord-310304-f28tjmi8 83 1 ( ( -LRB- cord-310304-f28tjmi8 83 2 Figure figure NN cord-310304-f28tjmi8 83 3 1 1 CD cord-310304-f28tjmi8 83 4 ) ) -RRB- cord-310304-f28tjmi8 83 5 . . . cord-310304-f28tjmi8 84 1 Controversy controversy NN cord-310304-f28tjmi8 84 2 surrounds surround VBZ cord-310304-f28tjmi8 84 3 the the DT cord-310304-f28tjmi8 84 4 discontinuation discontinuation NN cord-310304-f28tjmi8 84 5 of of IN cord-310304-f28tjmi8 84 6 angiotensin angiotensin NN cord-310304-f28tjmi8 84 7 receptor receptor NN cord-310304-f28tjmi8 84 8 blockers blocker NNS cord-310304-f28tjmi8 84 9 ( ( -LRB- cord-310304-f28tjmi8 84 10 ARBS ARBS NNP cord-310304-f28tjmi8 84 11 ) ) -RRB- cord-310304-f28tjmi8 84 12 and and CC cord-310304-f28tjmi8 84 13 ACEIs acei NNS cord-310304-f28tjmi8 84 14 for for IN cord-310304-f28tjmi8 84 15 diabetes diabetes NN cord-310304-f28tjmi8 84 16 and and CC cord-310304-f28tjmi8 84 17 hypertension hypertension NN cord-310304-f28tjmi8 84 18 treatment treatment NN cord-310304-f28tjmi8 84 19 in in IN cord-310304-f28tjmi8 84 20 COVID-19 covid-19 JJ cord-310304-f28tjmi8 84 21 patients patient NNS cord-310304-f28tjmi8 84 22 [ [ -LRB- cord-310304-f28tjmi8 84 23 52 52 CD cord-310304-f28tjmi8 84 24 ] ] -RRB- cord-310304-f28tjmi8 84 25 . . . cord-310304-f28tjmi8 85 1 However however RB cord-310304-f28tjmi8 85 2 , , , cord-310304-f28tjmi8 85 3 in in IN cord-310304-f28tjmi8 85 4 a a DT cord-310304-f28tjmi8 85 5 recent recent JJ cord-310304-f28tjmi8 85 6 study study NN cord-310304-f28tjmi8 85 7 involving involve VBG cord-310304-f28tjmi8 85 8 Renin renin NN cord-310304-f28tjmi8 85 9 - - HYPH cord-310304-f28tjmi8 85 10 angiotensin angiotensin NN cord-310304-f28tjmi8 85 11 - - HYPH cord-310304-f28tjmi8 85 12 aldosterone aldosterone NN cord-310304-f28tjmi8 85 13 system system NN cord-310304-f28tjmi8 85 14 inhibitors inhibitor NNS cord-310304-f28tjmi8 85 15 , , , cord-310304-f28tjmi8 85 16 it -PRON- PRP cord-310304-f28tjmi8 85 17 is be VBZ cord-310304-f28tjmi8 85 18 recommended recommend VBN cord-310304-f28tjmi8 85 19 that that IN cord-310304-f28tjmi8 85 20 these these DT cord-310304-f28tjmi8 85 21 drugs drug NNS cord-310304-f28tjmi8 85 22 be be VB cord-310304-f28tjmi8 85 23 continued continue VBN cord-310304-f28tjmi8 85 24 in in IN cord-310304-f28tjmi8 85 25 patients patient NNS cord-310304-f28tjmi8 85 26 evaluated evaluate VBN cord-310304-f28tjmi8 85 27 for for IN cord-310304-f28tjmi8 85 28 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 85 29 to to TO cord-310304-f28tjmi8 85 30 avoid avoid VB cord-310304-f28tjmi8 85 31 excess excess JJ cord-310304-f28tjmi8 85 32 cardiovascular cardiovascular JJ cord-310304-f28tjmi8 85 33 risk risk NN cord-310304-f28tjmi8 85 34 [ [ -LRB- cord-310304-f28tjmi8 85 35 53 53 CD cord-310304-f28tjmi8 85 36 ] ] -RRB- cord-310304-f28tjmi8 85 37 . . . cord-310304-f28tjmi8 86 1 Optimal optimal JJ cord-310304-f28tjmi8 86 2 care care NN cord-310304-f28tjmi8 86 3 of of IN cord-310304-f28tjmi8 86 4 diabetes diabetes NN cord-310304-f28tjmi8 86 5 patients patient NNS cord-310304-f28tjmi8 86 6 with with IN cord-310304-f28tjmi8 86 7 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 86 8 should should MD cord-310304-f28tjmi8 86 9 involve involve VB cord-310304-f28tjmi8 86 10 careful careful JJ cord-310304-f28tjmi8 86 11 monitoring monitoring NN cord-310304-f28tjmi8 86 12 of of IN cord-310304-f28tjmi8 86 13 corticosteroid corticosteroid NN cord-310304-f28tjmi8 86 14 therapy therapy NN cord-310304-f28tjmi8 86 15 when when WRB cord-310304-f28tjmi8 86 16 warranted warrant VBN cord-310304-f28tjmi8 86 17 , , , cord-310304-f28tjmi8 86 18 monitoring monitoring NN cord-310304-f28tjmi8 86 19 of of IN cord-310304-f28tjmi8 86 20 regular regular JJ cord-310304-f28tjmi8 86 21 blood blood NN cord-310304-f28tjmi8 86 22 glucose glucose NN cord-310304-f28tjmi8 86 23 , , , cord-310304-f28tjmi8 86 24 and and CC cord-310304-f28tjmi8 86 25 avoiding avoid VBG cord-310304-f28tjmi8 86 26 inappropriate inappropriate JJ cord-310304-f28tjmi8 86 27 discontinuation discontinuation NN cord-310304-f28tjmi8 86 28 of of IN cord-310304-f28tjmi8 86 29 ARBS arb NNS cord-310304-f28tjmi8 86 30 and and CC cord-310304-f28tjmi8 86 31 ACEIs acei NNS cord-310304-f28tjmi8 86 32 that that WDT cord-310304-f28tjmi8 86 33 may may MD cord-310304-f28tjmi8 86 34 increase increase VB cord-310304-f28tjmi8 86 35 morbidity morbidity NN cord-310304-f28tjmi8 86 36 in in IN cord-310304-f28tjmi8 86 37 COVID-19 covid-19 JJ cord-310304-f28tjmi8 86 38 patients patient NNS cord-310304-f28tjmi8 86 39 . . . cord-310304-f28tjmi8 87 1 ACE2 ACE2 NNP cord-310304-f28tjmi8 87 2 also also RB cord-310304-f28tjmi8 87 3 is be VBZ cord-310304-f28tjmi8 87 4 expressed express VBN cord-310304-f28tjmi8 87 5 in in IN cord-310304-f28tjmi8 87 6 heart heart NN cord-310304-f28tjmi8 87 7 , , , cord-310304-f28tjmi8 87 8 kidneys kidney NNS cord-310304-f28tjmi8 87 9 , , , cord-310304-f28tjmi8 87 10 vascular vascular JJ cord-310304-f28tjmi8 87 11 endothelium endothelium NN cord-310304-f28tjmi8 87 12 , , , cord-310304-f28tjmi8 87 13 and and CC cord-310304-f28tjmi8 87 14 intestinal intestinal JJ cord-310304-f28tjmi8 87 15 epithelium epithelium NN cord-310304-f28tjmi8 87 16 , , , cord-310304-f28tjmi8 87 17 supporting support VBG cord-310304-f28tjmi8 87 18 the the DT cord-310304-f28tjmi8 87 19 notion notion NN cord-310304-f28tjmi8 87 20 that that IN cord-310304-f28tjmi8 87 21 virus virus NN cord-310304-f28tjmi8 87 22 interaction interaction NN cord-310304-f28tjmi8 87 23 with with IN cord-310304-f28tjmi8 87 24 several several JJ cord-310304-f28tjmi8 87 25 organ organ NN cord-310304-f28tjmi8 87 26 systems system NNS cord-310304-f28tjmi8 87 27 could could MD cord-310304-f28tjmi8 87 28 lead lead VB cord-310304-f28tjmi8 87 29 to to IN cord-310304-f28tjmi8 87 30 MOD mod NN cord-310304-f28tjmi8 87 31 , , , cord-310304-f28tjmi8 87 32 which which WDT cord-310304-f28tjmi8 87 33 may may MD cord-310304-f28tjmi8 87 34 be be VB cord-310304-f28tjmi8 87 35 observed observe VBN cord-310304-f28tjmi8 87 36 in in IN cord-310304-f28tjmi8 88 1 COVID-19 covid-19 JJ cord-310304-f28tjmi8 88 2 patients patient NNS cord-310304-f28tjmi8 88 3 [ [ -LRB- cord-310304-f28tjmi8 88 4 54 54 CD cord-310304-f28tjmi8 88 5 , , , cord-310304-f28tjmi8 88 6 55 55 CD cord-310304-f28tjmi8 88 7 ] ] -RRB- cord-310304-f28tjmi8 88 8 . . . cord-310304-f28tjmi8 89 1 treatment treatment NN cord-310304-f28tjmi8 89 2 of of IN cord-310304-f28tjmi8 89 3 hypertension hypertension NN cord-310304-f28tjmi8 89 4 with with IN cord-310304-f28tjmi8 89 5 ACEIs acei NNS cord-310304-f28tjmi8 89 6 is be VBZ cord-310304-f28tjmi8 89 7 beneficial beneficial JJ cord-310304-f28tjmi8 89 8 or or CC cord-310304-f28tjmi8 89 9 counter counter JJ cord-310304-f28tjmi8 89 10 - - JJ cord-310304-f28tjmi8 89 11 productive productive JJ cord-310304-f28tjmi8 89 12 in in IN cord-310304-f28tjmi8 89 13 COVID-19 covid-19 JJ cord-310304-f28tjmi8 89 14 patients patient NNS cord-310304-f28tjmi8 89 15 . . . cord-310304-f28tjmi8 90 1 Studies study NNS cord-310304-f28tjmi8 90 2 have have VBP cord-310304-f28tjmi8 90 3 shown show VBN cord-310304-f28tjmi8 90 4 the the DT cord-310304-f28tjmi8 90 5 ACEIs acei NNS cord-310304-f28tjmi8 90 6 have have VB cord-310304-f28tjmi8 90 7 a a DT cord-310304-f28tjmi8 90 8 protective protective JJ cord-310304-f28tjmi8 90 9 anti anti JJ cord-310304-f28tjmi8 90 10 - - JJ cord-310304-f28tjmi8 90 11 inflammatory inflammatory JJ cord-310304-f28tjmi8 90 12 effect effect NN cord-310304-f28tjmi8 90 13 in in IN cord-310304-f28tjmi8 90 14 the the DT cord-310304-f28tjmi8 90 15 lung lung NN cord-310304-f28tjmi8 90 16 , , , cord-310304-f28tjmi8 90 17 and and CC cord-310304-f28tjmi8 90 18 soluble soluble JJ cord-310304-f28tjmi8 90 19 ACEIs acei NNS cord-310304-f28tjmi8 90 20 could could MD cord-310304-f28tjmi8 90 21 bind bind VB cord-310304-f28tjmi8 90 22 free free JJ cord-310304-f28tjmi8 90 23 virus virus NN cord-310304-f28tjmi8 90 24 and and CC cord-310304-f28tjmi8 90 25 serve serve VB cord-310304-f28tjmi8 90 26 as as IN cord-310304-f28tjmi8 90 27 therapeutics therapeutic NNS cord-310304-f28tjmi8 90 28 to to TO cord-310304-f28tjmi8 90 29 reduce reduce VB cord-310304-f28tjmi8 90 30 virus virus NN cord-310304-f28tjmi8 90 31 load load NN cord-310304-f28tjmi8 90 32 [ [ -LRB- cord-310304-f28tjmi8 90 33 47 47 CD cord-310304-f28tjmi8 90 34 ] ] -RRB- cord-310304-f28tjmi8 90 35 [ [ -LRB- cord-310304-f28tjmi8 90 36 48 48 CD cord-310304-f28tjmi8 90 37 ] ] -RRB- cord-310304-f28tjmi8 90 38 [ [ -LRB- cord-310304-f28tjmi8 90 39 49 49 CD cord-310304-f28tjmi8 90 40 ] ] -RRB- cord-310304-f28tjmi8 90 41 . . . cord-310304-f28tjmi8 91 1 If if IN cord-310304-f28tjmi8 91 2 corticosteroid corticosteroid NN cord-310304-f28tjmi8 91 3 therapy therapy NN cord-310304-f28tjmi8 91 4 is be VBZ cord-310304-f28tjmi8 91 5 recommended recommend VBN cord-310304-f28tjmi8 91 6 for for IN cord-310304-f28tjmi8 91 7 COVID-19 covid-19 JJ cord-310304-f28tjmi8 91 8 patients patient NNS cord-310304-f28tjmi8 91 9 , , , cord-310304-f28tjmi8 91 10 glucose glucose NN cord-310304-f28tjmi8 91 11 levels level NNS cord-310304-f28tjmi8 91 12 should should MD cord-310304-f28tjmi8 91 13 be be VB cord-310304-f28tjmi8 91 14 monitored monitor VBN cord-310304-f28tjmi8 91 15 carefully carefully RB cord-310304-f28tjmi8 91 16 to to TO cord-310304-f28tjmi8 91 17 avoid avoid VB cord-310304-f28tjmi8 91 18 pulmonary pulmonary JJ cord-310304-f28tjmi8 91 19 and and CC cord-310304-f28tjmi8 91 20 immune immune JJ cord-310304-f28tjmi8 91 21 dysfunction dysfunction NN cord-310304-f28tjmi8 91 22 [ [ -LRB- cord-310304-f28tjmi8 91 23 50 50 CD cord-310304-f28tjmi8 91 24 , , , cord-310304-f28tjmi8 91 25 51 51 CD cord-310304-f28tjmi8 91 26 ] ] -RRB- cord-310304-f28tjmi8 92 1 ( ( -LRB- cord-310304-f28tjmi8 92 2 Figure figure NN cord-310304-f28tjmi8 92 3 1 1 CD cord-310304-f28tjmi8 92 4 ) ) -RRB- cord-310304-f28tjmi8 92 5 . . . cord-310304-f28tjmi8 93 1 Controversy controversy NN cord-310304-f28tjmi8 93 2 surrounds surround VBZ cord-310304-f28tjmi8 93 3 the the DT cord-310304-f28tjmi8 93 4 discontinuation discontinuation NN cord-310304-f28tjmi8 93 5 of of IN cord-310304-f28tjmi8 93 6 angiotensin angiotensin NN cord-310304-f28tjmi8 93 7 receptor receptor NN cord-310304-f28tjmi8 93 8 blockers blocker NNS cord-310304-f28tjmi8 93 9 ( ( -LRB- cord-310304-f28tjmi8 93 10 ARBS ARBS NNP cord-310304-f28tjmi8 93 11 ) ) -RRB- cord-310304-f28tjmi8 93 12 and and CC cord-310304-f28tjmi8 93 13 ACEIs acei NNS cord-310304-f28tjmi8 93 14 for for IN cord-310304-f28tjmi8 93 15 diabetes diabetes NN cord-310304-f28tjmi8 93 16 and and CC cord-310304-f28tjmi8 93 17 hypertension hypertension NN cord-310304-f28tjmi8 93 18 treatment treatment NN cord-310304-f28tjmi8 93 19 in in IN cord-310304-f28tjmi8 93 20 COVID-19 covid-19 JJ cord-310304-f28tjmi8 93 21 patients patient NNS cord-310304-f28tjmi8 93 22 [ [ -LRB- cord-310304-f28tjmi8 93 23 52 52 CD cord-310304-f28tjmi8 93 24 ] ] -RRB- cord-310304-f28tjmi8 93 25 . . . cord-310304-f28tjmi8 94 1 However however RB cord-310304-f28tjmi8 94 2 , , , cord-310304-f28tjmi8 94 3 in in IN cord-310304-f28tjmi8 94 4 a a DT cord-310304-f28tjmi8 94 5 recent recent JJ cord-310304-f28tjmi8 94 6 study study NN cord-310304-f28tjmi8 94 7 involving involve VBG cord-310304-f28tjmi8 94 8 Renin renin NN cord-310304-f28tjmi8 94 9 - - HYPH cord-310304-f28tjmi8 94 10 angiotensinaldosterone angiotensinaldosterone NN cord-310304-f28tjmi8 94 11 system system NN cord-310304-f28tjmi8 94 12 inhibitors inhibitor NNS cord-310304-f28tjmi8 94 13 , , , cord-310304-f28tjmi8 94 14 it -PRON- PRP cord-310304-f28tjmi8 94 15 is be VBZ cord-310304-f28tjmi8 94 16 recommended recommend VBN cord-310304-f28tjmi8 94 17 that that IN cord-310304-f28tjmi8 94 18 these these DT cord-310304-f28tjmi8 94 19 drugs drug NNS cord-310304-f28tjmi8 94 20 be be VB cord-310304-f28tjmi8 94 21 continued continue VBN cord-310304-f28tjmi8 94 22 in in IN cord-310304-f28tjmi8 94 23 patients patient NNS cord-310304-f28tjmi8 94 24 evaluated evaluate VBN cord-310304-f28tjmi8 94 25 for for IN cord-310304-f28tjmi8 94 26 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 94 27 to to TO cord-310304-f28tjmi8 94 28 avoid avoid VB cord-310304-f28tjmi8 94 29 excess excess JJ cord-310304-f28tjmi8 94 30 cardiovascular cardiovascular JJ cord-310304-f28tjmi8 94 31 risk risk NN cord-310304-f28tjmi8 94 32 [ [ -LRB- cord-310304-f28tjmi8 94 33 53 53 CD cord-310304-f28tjmi8 94 34 ] ] -RRB- cord-310304-f28tjmi8 94 35 . . . cord-310304-f28tjmi8 95 1 Optimal optimal JJ cord-310304-f28tjmi8 95 2 care care NN cord-310304-f28tjmi8 95 3 of of IN cord-310304-f28tjmi8 95 4 diabetes diabetes NN cord-310304-f28tjmi8 95 5 patients patient NNS cord-310304-f28tjmi8 95 6 with with IN cord-310304-f28tjmi8 95 7 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 95 8 should should MD cord-310304-f28tjmi8 95 9 involve involve VB cord-310304-f28tjmi8 95 10 careful careful JJ cord-310304-f28tjmi8 95 11 monitoring monitoring NN cord-310304-f28tjmi8 95 12 of of IN cord-310304-f28tjmi8 95 13 corticosteroid corticosteroid NN cord-310304-f28tjmi8 95 14 therapy therapy NN cord-310304-f28tjmi8 95 15 when when WRB cord-310304-f28tjmi8 95 16 warranted warrant VBN cord-310304-f28tjmi8 95 17 , , , cord-310304-f28tjmi8 95 18 monitoring monitoring NN cord-310304-f28tjmi8 95 19 of of IN cord-310304-f28tjmi8 95 20 regular regular JJ cord-310304-f28tjmi8 95 21 blood blood NN cord-310304-f28tjmi8 95 22 glucose glucose NN cord-310304-f28tjmi8 95 23 , , , cord-310304-f28tjmi8 95 24 and and CC cord-310304-f28tjmi8 95 25 avoiding avoid VBG cord-310304-f28tjmi8 95 26 inappropriate inappropriate JJ cord-310304-f28tjmi8 95 27 discontinuation discontinuation NN cord-310304-f28tjmi8 95 28 of of IN cord-310304-f28tjmi8 95 29 ARBS arb NNS cord-310304-f28tjmi8 95 30 and and CC cord-310304-f28tjmi8 95 31 ACEIs acei NNS cord-310304-f28tjmi8 95 32 that that WDT cord-310304-f28tjmi8 95 33 may may MD cord-310304-f28tjmi8 95 34 increase increase VB cord-310304-f28tjmi8 95 35 morbidity morbidity NN cord-310304-f28tjmi8 95 36 in in IN cord-310304-f28tjmi8 95 37 COVID-19 covid-19 JJ cord-310304-f28tjmi8 95 38 patients patient NNS cord-310304-f28tjmi8 95 39 . . . cord-310304-f28tjmi8 96 1 ACE2 ACE2 NNP cord-310304-f28tjmi8 96 2 also also RB cord-310304-f28tjmi8 96 3 is be VBZ cord-310304-f28tjmi8 96 4 expressed express VBN cord-310304-f28tjmi8 96 5 in in IN cord-310304-f28tjmi8 96 6 heart heart NN cord-310304-f28tjmi8 96 7 , , , cord-310304-f28tjmi8 96 8 kidneys kidney NNS cord-310304-f28tjmi8 96 9 , , , cord-310304-f28tjmi8 96 10 vascular vascular JJ cord-310304-f28tjmi8 96 11 endothelium endothelium NN cord-310304-f28tjmi8 96 12 , , , cord-310304-f28tjmi8 96 13 and and CC cord-310304-f28tjmi8 96 14 intestinal intestinal JJ cord-310304-f28tjmi8 96 15 epithelium epithelium NN cord-310304-f28tjmi8 96 16 , , , cord-310304-f28tjmi8 96 17 supporting support VBG cord-310304-f28tjmi8 96 18 the the DT cord-310304-f28tjmi8 96 19 notion notion NN cord-310304-f28tjmi8 96 20 that that IN cord-310304-f28tjmi8 96 21 virus virus NN cord-310304-f28tjmi8 96 22 interaction interaction NN cord-310304-f28tjmi8 96 23 with with IN cord-310304-f28tjmi8 96 24 several several JJ cord-310304-f28tjmi8 96 25 organ organ NN cord-310304-f28tjmi8 96 26 systems system NNS cord-310304-f28tjmi8 96 27 could could MD cord-310304-f28tjmi8 96 28 lead lead VB cord-310304-f28tjmi8 96 29 to to IN cord-310304-f28tjmi8 96 30 MOD mod NN cord-310304-f28tjmi8 96 31 , , , cord-310304-f28tjmi8 96 32 which which WDT cord-310304-f28tjmi8 96 33 may may MD cord-310304-f28tjmi8 96 34 be be VB cord-310304-f28tjmi8 96 35 observed observe VBN cord-310304-f28tjmi8 96 36 in in IN cord-310304-f28tjmi8 97 1 COVID-19 covid-19 JJ cord-310304-f28tjmi8 97 2 patients patient NNS cord-310304-f28tjmi8 97 3 [ [ -LRB- cord-310304-f28tjmi8 97 4 54 54 CD cord-310304-f28tjmi8 97 5 , , , cord-310304-f28tjmi8 97 6 55 55 CD cord-310304-f28tjmi8 97 7 ] ] -RRB- cord-310304-f28tjmi8 97 8 . . . cord-310304-f28tjmi8 98 1 Hypothetical hypothetical JJ cord-310304-f28tjmi8 98 2 model model NN cord-310304-f28tjmi8 98 3 of of IN cord-310304-f28tjmi8 98 4 uncontrolled uncontrolled JJ cord-310304-f28tjmi8 98 5 blood blood NN cord-310304-f28tjmi8 98 6 pressure pressure NN cord-310304-f28tjmi8 98 7 in in IN cord-310304-f28tjmi8 98 8 patients patient NNS cord-310304-f28tjmi8 98 9 with with IN cord-310304-f28tjmi8 98 10 hypertension hypertension NN cord-310304-f28tjmi8 98 11 and and CC cord-310304-f28tjmi8 98 12 increased increase VBN cord-310304-f28tjmi8 98 13 risk risk NN cord-310304-f28tjmi8 98 14 for for IN cord-310304-f28tjmi8 98 15 complications complication NNS cord-310304-f28tjmi8 98 16 due due JJ cord-310304-f28tjmi8 98 17 to to IN cord-310304-f28tjmi8 98 18 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 98 19 . . . cord-310304-f28tjmi8 99 1 The the DT cord-310304-f28tjmi8 99 2 liver liver NN cord-310304-f28tjmi8 99 3 produces produce VBZ cord-310304-f28tjmi8 99 4 angiotensinogen angiotensinogen NNP cord-310304-f28tjmi8 99 5 , , , cord-310304-f28tjmi8 99 6 a a DT cord-310304-f28tjmi8 99 7 peptide peptide JJ cord-310304-f28tjmi8 99 8 hormone hormone NN cord-310304-f28tjmi8 99 9 that that WDT cord-310304-f28tjmi8 99 10 causes cause VBZ cord-310304-f28tjmi8 99 11 vasoconstriction vasoconstriction NN cord-310304-f28tjmi8 99 12 that that WDT cord-310304-f28tjmi8 99 13 increases increase VBZ cord-310304-f28tjmi8 99 14 blood blood NN cord-310304-f28tjmi8 99 15 pressure pressure NN cord-310304-f28tjmi8 99 16 . . . cord-310304-f28tjmi8 100 1 Angiotensinogen Angiotensinogen NNP cord-310304-f28tjmi8 100 2 is be VBZ cord-310304-f28tjmi8 100 3 converted convert VBN cord-310304-f28tjmi8 100 4 to to IN cord-310304-f28tjmi8 100 5 angiotensin angiotensin NN cord-310304-f28tjmi8 100 6 I -PRON- PRP cord-310304-f28tjmi8 100 7 by by IN cord-310304-f28tjmi8 100 8 renin renin NN cord-310304-f28tjmi8 100 9 from from IN cord-310304-f28tjmi8 100 10 the the DT cord-310304-f28tjmi8 100 11 kidneys kidney NNS cord-310304-f28tjmi8 100 12 then then RB cord-310304-f28tjmi8 100 13 is be VBZ cord-310304-f28tjmi8 100 14 converted convert VBN cord-310304-f28tjmi8 100 15 to to IN cord-310304-f28tjmi8 100 16 angiotensin angiotensin NN cord-310304-f28tjmi8 100 17 II II NNP cord-310304-f28tjmi8 100 18 by by IN cord-310304-f28tjmi8 100 19 the the DT cord-310304-f28tjmi8 100 20 action action NN cord-310304-f28tjmi8 100 21 of of IN cord-310304-f28tjmi8 100 22 ACE ACE NNP cord-310304-f28tjmi8 100 23 ( ( -LRB- cord-310304-f28tjmi8 100 24 ACE ace NN cord-310304-f28tjmi8 100 25 - - HYPH cord-310304-f28tjmi8 100 26 I I NNP cord-310304-f28tjmi8 100 27 ) ) -RRB- cord-310304-f28tjmi8 100 28 . . . cord-310304-f28tjmi8 101 1 Normally normally RB cord-310304-f28tjmi8 101 2 angiotensin angiotensin NN cord-310304-f28tjmi8 101 3 II II NNP cord-310304-f28tjmi8 101 4 ( ( -LRB- cord-310304-f28tjmi8 101 5 Ang Ang NNP cord-310304-f28tjmi8 101 6 . . . cord-310304-f28tjmi8 101 7 II II NNP cord-310304-f28tjmi8 101 8 ) ) -RRB- cord-310304-f28tjmi8 101 9 is be VBZ cord-310304-f28tjmi8 101 10 converted convert VBN cord-310304-f28tjmi8 101 11 to to IN cord-310304-f28tjmi8 101 12 angiotensin-1 angiotensin-1 NNP cord-310304-f28tjmi8 101 13 - - HYPH cord-310304-f28tjmi8 101 14 7 7 CD cord-310304-f28tjmi8 101 15 by by IN cord-310304-f28tjmi8 101 16 the the DT cord-310304-f28tjmi8 101 17 monocarboxypetidase monocarboxypetidase NNP cord-310304-f28tjmi8 101 18 ACEI ACEI NNP cord-310304-f28tjmi8 101 19 homology homology NN cord-310304-f28tjmi8 101 20 ACE2 ACE2 NNP cord-310304-f28tjmi8 101 21 . . . cord-310304-f28tjmi8 102 1 However however RB cord-310304-f28tjmi8 102 2 , , , cord-310304-f28tjmi8 102 3 upon upon IN cord-310304-f28tjmi8 102 4 infection infection NN cord-310304-f28tjmi8 102 5 with with IN cord-310304-f28tjmi8 102 6 SARS SARS NNP cord-310304-f28tjmi8 102 7 - - HYPH cord-310304-f28tjmi8 102 8 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 102 9 the the DT cord-310304-f28tjmi8 102 10 ACE2 ACE2 NNP cord-310304-f28tjmi8 102 11 protein protein NN cord-310304-f28tjmi8 102 12 serves serve VBZ cord-310304-f28tjmi8 102 13 as as IN cord-310304-f28tjmi8 102 14 the the DT cord-310304-f28tjmi8 102 15 entry entry NN cord-310304-f28tjmi8 102 16 receptor receptor NN cord-310304-f28tjmi8 102 17 for for IN cord-310304-f28tjmi8 102 18 the the DT cord-310304-f28tjmi8 102 19 virus virus NN cord-310304-f28tjmi8 102 20 and and CC cord-310304-f28tjmi8 102 21 is be VBZ cord-310304-f28tjmi8 102 22 internalized internalize VBN cord-310304-f28tjmi8 102 23 in in IN cord-310304-f28tjmi8 102 24 the the DT cord-310304-f28tjmi8 102 25 endosome endosome NN cord-310304-f28tjmi8 102 26 with with IN cord-310304-f28tjmi8 102 27 SARS SARS NNP cord-310304-f28tjmi8 102 28 - - HYPH cord-310304-f28tjmi8 102 29 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 102 30 during during IN cord-310304-f28tjmi8 102 31 membrane membrane NN cord-310304-f28tjmi8 102 32 fusion fusion NN cord-310304-f28tjmi8 102 33 and and CC cord-310304-f28tjmi8 102 34 uptake uptake NN cord-310304-f28tjmi8 102 35 by by IN cord-310304-f28tjmi8 102 36 Hypothetical hypothetical JJ cord-310304-f28tjmi8 102 37 model model NN cord-310304-f28tjmi8 102 38 of of IN cord-310304-f28tjmi8 102 39 uncontrolled uncontrolled JJ cord-310304-f28tjmi8 102 40 blood blood NN cord-310304-f28tjmi8 102 41 pressure pressure NN cord-310304-f28tjmi8 102 42 in in IN cord-310304-f28tjmi8 102 43 patients patient NNS cord-310304-f28tjmi8 102 44 with with IN cord-310304-f28tjmi8 102 45 hypertension hypertension NN cord-310304-f28tjmi8 102 46 and and CC cord-310304-f28tjmi8 102 47 increased increase VBN cord-310304-f28tjmi8 102 48 risk risk NN cord-310304-f28tjmi8 102 49 for for IN cord-310304-f28tjmi8 102 50 complications complication NNS cord-310304-f28tjmi8 102 51 due due JJ cord-310304-f28tjmi8 102 52 to to IN cord-310304-f28tjmi8 102 53 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 102 54 . . . cord-310304-f28tjmi8 103 1 The the DT cord-310304-f28tjmi8 103 2 liver liver NN cord-310304-f28tjmi8 103 3 produces produce VBZ cord-310304-f28tjmi8 103 4 angiotensinogen angiotensinogen NNP cord-310304-f28tjmi8 103 5 , , , cord-310304-f28tjmi8 103 6 a a DT cord-310304-f28tjmi8 103 7 peptide peptide JJ cord-310304-f28tjmi8 103 8 hormone hormone NN cord-310304-f28tjmi8 103 9 that that WDT cord-310304-f28tjmi8 103 10 causes cause VBZ cord-310304-f28tjmi8 103 11 vasoconstriction vasoconstriction NN cord-310304-f28tjmi8 103 12 that that WDT cord-310304-f28tjmi8 103 13 increases increase VBZ cord-310304-f28tjmi8 103 14 blood blood NN cord-310304-f28tjmi8 103 15 pressure pressure NN cord-310304-f28tjmi8 103 16 . . . cord-310304-f28tjmi8 104 1 Angiotensinogen Angiotensinogen NNP cord-310304-f28tjmi8 104 2 is be VBZ cord-310304-f28tjmi8 104 3 converted convert VBN cord-310304-f28tjmi8 104 4 to to IN cord-310304-f28tjmi8 104 5 angiotensin angiotensin NN cord-310304-f28tjmi8 104 6 I -PRON- PRP cord-310304-f28tjmi8 104 7 by by IN cord-310304-f28tjmi8 104 8 renin renin NN cord-310304-f28tjmi8 104 9 from from IN cord-310304-f28tjmi8 104 10 the the DT cord-310304-f28tjmi8 104 11 kidneys kidney NNS cord-310304-f28tjmi8 104 12 then then RB cord-310304-f28tjmi8 104 13 is be VBZ cord-310304-f28tjmi8 104 14 converted convert VBN cord-310304-f28tjmi8 104 15 to to IN cord-310304-f28tjmi8 104 16 angiotensin angiotensin NN cord-310304-f28tjmi8 104 17 II II NNP cord-310304-f28tjmi8 104 18 by by IN cord-310304-f28tjmi8 104 19 the the DT cord-310304-f28tjmi8 104 20 action action NN cord-310304-f28tjmi8 104 21 of of IN cord-310304-f28tjmi8 104 22 ACE ACE NNP cord-310304-f28tjmi8 104 23 ( ( -LRB- cord-310304-f28tjmi8 104 24 ACE ace NN cord-310304-f28tjmi8 104 25 - - HYPH cord-310304-f28tjmi8 104 26 I I NNP cord-310304-f28tjmi8 104 27 ) ) -RRB- cord-310304-f28tjmi8 104 28 . . . cord-310304-f28tjmi8 105 1 Normally normally RB cord-310304-f28tjmi8 105 2 angiotensin angiotensin NN cord-310304-f28tjmi8 105 3 II II NNP cord-310304-f28tjmi8 105 4 ( ( -LRB- cord-310304-f28tjmi8 105 5 Ang Ang NNP cord-310304-f28tjmi8 105 6 . . . cord-310304-f28tjmi8 105 7 II II NNP cord-310304-f28tjmi8 105 8 ) ) -RRB- cord-310304-f28tjmi8 105 9 is be VBZ cord-310304-f28tjmi8 105 10 converted convert VBN cord-310304-f28tjmi8 105 11 to to IN cord-310304-f28tjmi8 105 12 angiotensin-1 angiotensin-1 NNP cord-310304-f28tjmi8 105 13 - - HYPH cord-310304-f28tjmi8 105 14 7 7 CD cord-310304-f28tjmi8 105 15 by by IN cord-310304-f28tjmi8 105 16 the the DT cord-310304-f28tjmi8 105 17 monocarboxypetidase monocarboxypetidase NNP cord-310304-f28tjmi8 105 18 ACEI ACEI NNP cord-310304-f28tjmi8 105 19 homology homology NN cord-310304-f28tjmi8 105 20 ACE2 ACE2 NNP cord-310304-f28tjmi8 105 21 . . . cord-310304-f28tjmi8 106 1 However however RB cord-310304-f28tjmi8 106 2 , , , cord-310304-f28tjmi8 106 3 upon upon IN cord-310304-f28tjmi8 106 4 infection infection NN cord-310304-f28tjmi8 106 5 with with IN cord-310304-f28tjmi8 106 6 SARS SARS NNP cord-310304-f28tjmi8 106 7 - - HYPH cord-310304-f28tjmi8 106 8 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 106 9 the the DT cord-310304-f28tjmi8 106 10 ACE2 ACE2 NNP cord-310304-f28tjmi8 106 11 protein protein NN cord-310304-f28tjmi8 106 12 serves serve VBZ cord-310304-f28tjmi8 106 13 as as IN cord-310304-f28tjmi8 106 14 the the DT cord-310304-f28tjmi8 106 15 entry entry NN cord-310304-f28tjmi8 106 16 receptor receptor NN cord-310304-f28tjmi8 106 17 for for IN cord-310304-f28tjmi8 106 18 the the DT cord-310304-f28tjmi8 106 19 virus virus NN cord-310304-f28tjmi8 106 20 and and CC cord-310304-f28tjmi8 106 21 is be VBZ cord-310304-f28tjmi8 106 22 internalized internalize VBN cord-310304-f28tjmi8 106 23 in in IN cord-310304-f28tjmi8 106 24 the the DT cord-310304-f28tjmi8 106 25 endosome endosome NN cord-310304-f28tjmi8 106 26 with with IN cord-310304-f28tjmi8 106 27 SARS SARS NNP cord-310304-f28tjmi8 106 28 - - HYPH cord-310304-f28tjmi8 106 29 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 106 30 during during IN cord-310304-f28tjmi8 106 31 membrane membrane NN cord-310304-f28tjmi8 106 32 fusion fusion NN cord-310304-f28tjmi8 106 33 and and CC cord-310304-f28tjmi8 106 34 uptake uptake NN cord-310304-f28tjmi8 106 35 by by IN cord-310304-f28tjmi8 106 36 infected infected JJ cord-310304-f28tjmi8 106 37 cells cell NNS cord-310304-f28tjmi8 106 38 . . . cord-310304-f28tjmi8 107 1 This this DT cord-310304-f28tjmi8 107 2 leads lead VBZ cord-310304-f28tjmi8 107 3 to to IN cord-310304-f28tjmi8 107 4 significant significant JJ cord-310304-f28tjmi8 107 5 reduction reduction NN cord-310304-f28tjmi8 107 6 in in IN cord-310304-f28tjmi8 107 7 ACE2 ACE2 NNP cord-310304-f28tjmi8 107 8 surface surface NN cord-310304-f28tjmi8 107 9 expression expression NN cord-310304-f28tjmi8 107 10 and and CC cord-310304-f28tjmi8 107 11 concomitant concomitant JJ cord-310304-f28tjmi8 107 12 increase increase NN cord-310304-f28tjmi8 107 13 in in IN cord-310304-f28tjmi8 107 14 angiotensin angiotensin NN cord-310304-f28tjmi8 107 15 II II NNP cord-310304-f28tjmi8 107 16 , , , cord-310304-f28tjmi8 107 17 further further RB cord-310304-f28tjmi8 107 18 leading lead VBG cord-310304-f28tjmi8 107 19 to to IN cord-310304-f28tjmi8 107 20 vasoconstriction vasoconstriction NN cord-310304-f28tjmi8 107 21 that that WDT cord-310304-f28tjmi8 107 22 impacts impact VBZ cord-310304-f28tjmi8 107 23 blood blood NN cord-310304-f28tjmi8 107 24 pressure pressure NN cord-310304-f28tjmi8 107 25 , , , cord-310304-f28tjmi8 107 26 inflammation inflammation NN cord-310304-f28tjmi8 107 27 , , , cord-310304-f28tjmi8 107 28 fibrosis fibrosis NN cord-310304-f28tjmi8 107 29 , , , cord-310304-f28tjmi8 107 30 and and CC cord-310304-f28tjmi8 107 31 oxidative oxidative JJ cord-310304-f28tjmi8 107 32 stress stress NN cord-310304-f28tjmi8 107 33 in in IN cord-310304-f28tjmi8 107 34 infected infected JJ cord-310304-f28tjmi8 107 35 cells cell NNS cord-310304-f28tjmi8 107 36 and and CC cord-310304-f28tjmi8 107 37 tissues tissue NNS cord-310304-f28tjmi8 107 38 in in IN cord-310304-f28tjmi8 107 39 multiple multiple JJ cord-310304-f28tjmi8 107 40 organs organ NNS cord-310304-f28tjmi8 107 41 . . . cord-310304-f28tjmi8 108 1 Even even RB cord-310304-f28tjmi8 108 2 more more RBR cord-310304-f28tjmi8 108 3 , , , cord-310304-f28tjmi8 108 4 the the DT cord-310304-f28tjmi8 108 5 downregulation downregulation NN cord-310304-f28tjmi8 108 6 of of IN cord-310304-f28tjmi8 108 7 ACE2 ACE2 NNP cord-310304-f28tjmi8 108 8 leads lead VBZ cord-310304-f28tjmi8 108 9 to to IN cord-310304-f28tjmi8 108 10 the the DT cord-310304-f28tjmi8 108 11 upregulation upregulation NN cord-310304-f28tjmi8 108 12 of of IN cord-310304-f28tjmi8 108 13 aldosterone aldosterone NN cord-310304-f28tjmi8 108 14 , , , cord-310304-f28tjmi8 108 15 a a DT cord-310304-f28tjmi8 108 16 steroid steroid NN cord-310304-f28tjmi8 108 17 hormone hormone NN cord-310304-f28tjmi8 108 18 produced produce VBN cord-310304-f28tjmi8 108 19 by by IN cord-310304-f28tjmi8 108 20 the the DT cord-310304-f28tjmi8 108 21 zona zona NNP cord-310304-f28tjmi8 108 22 glomerulosa glomerulosa NNP cord-310304-f28tjmi8 108 23 of of IN cord-310304-f28tjmi8 108 24 the the DT cord-310304-f28tjmi8 108 25 adrenal adrenal JJ cord-310304-f28tjmi8 108 26 cortex cortex NN cord-310304-f28tjmi8 108 27 , , , cord-310304-f28tjmi8 108 28 which which WDT cord-310304-f28tjmi8 108 29 increases increase VBZ cord-310304-f28tjmi8 108 30 the the DT cord-310304-f28tjmi8 108 31 activity activity NN cord-310304-f28tjmi8 108 32 of of IN cord-310304-f28tjmi8 108 33 ACE1 ace1 CD cord-310304-f28tjmi8 108 34 . . . cord-310304-f28tjmi8 109 1 This this DT cord-310304-f28tjmi8 109 2 action action NN cord-310304-f28tjmi8 109 3 leads lead VBZ cord-310304-f28tjmi8 109 4 to to IN cord-310304-f28tjmi8 109 5 higher high JJR cord-310304-f28tjmi8 109 6 levels level NNS cord-310304-f28tjmi8 109 7 of of IN cord-310304-f28tjmi8 109 8 angiotensin angiotensin NN cord-310304-f28tjmi8 109 9 II II NNP cord-310304-f28tjmi8 109 10 and and CC cord-310304-f28tjmi8 109 11 an an DT cord-310304-f28tjmi8 109 12 overall overall JJ cord-310304-f28tjmi8 109 13 suppression suppression NN cord-310304-f28tjmi8 109 14 of of IN cord-310304-f28tjmi8 109 15 angiotensin-1 angiotensin-1 NNP cord-310304-f28tjmi8 109 16 - - HYPH cord-310304-f28tjmi8 109 17 7 7 CD cord-310304-f28tjmi8 109 18 , , , cord-310304-f28tjmi8 109 19 which which WDT cord-310304-f28tjmi8 109 20 is be VBZ cord-310304-f28tjmi8 109 21 designed design VBN cord-310304-f28tjmi8 109 22 to to TO cord-310304-f28tjmi8 109 23 mitigate mitigate VB cord-310304-f28tjmi8 109 24 the the DT cord-310304-f28tjmi8 109 25 effects effect NNS cord-310304-f28tjmi8 109 26 of of IN cord-310304-f28tjmi8 109 27 angiotensin angiotensin NN cord-310304-f28tjmi8 109 28 II II NNP cord-310304-f28tjmi8 109 29 via via IN cord-310304-f28tjmi8 109 30 vasodilation vasodilation NN cord-310304-f28tjmi8 109 31 , , , cord-310304-f28tjmi8 109 32 anti anti JJ cord-310304-f28tjmi8 109 33 - - JJ cord-310304-f28tjmi8 109 34 inflammatory inflammatory JJ cord-310304-f28tjmi8 109 35 effects effect NNS cord-310304-f28tjmi8 109 36 , , , cord-310304-f28tjmi8 109 37 and and CC cord-310304-f28tjmi8 109 38 anti anti JJ cord-310304-f28tjmi8 109 39 - - JJ cord-310304-f28tjmi8 109 40 oxidation oxidation JJ cord-310304-f28tjmi8 109 41 . . . cord-310304-f28tjmi8 110 1 These these DT cord-310304-f28tjmi8 110 2 levels level NNS cord-310304-f28tjmi8 110 3 of of IN cord-310304-f28tjmi8 110 4 angiotensin angiotensin NN cord-310304-f28tjmi8 110 5 II II NNP cord-310304-f28tjmi8 110 6 may may MD cord-310304-f28tjmi8 110 7 result result VB cord-310304-f28tjmi8 110 8 in in IN cord-310304-f28tjmi8 110 9 MOD mod NN cord-310304-f28tjmi8 110 10 or or CC cord-310304-f28tjmi8 110 11 failure failure NN cord-310304-f28tjmi8 110 12 . . . cord-310304-f28tjmi8 111 1 RAASA RAASA NNP cord-310304-f28tjmi8 111 2 ( ( -LRB- cord-310304-f28tjmi8 111 3 renin renin NN cord-310304-f28tjmi8 111 4 - - HYPH cord-310304-f28tjmi8 111 5 angiotensin angiotensin NN cord-310304-f28tjmi8 111 6 - - HYPH cord-310304-f28tjmi8 111 7 aldosterone aldosterone NN cord-310304-f28tjmi8 111 8 system system NN cord-310304-f28tjmi8 111 9 antagonist antagonist NN cord-310304-f28tjmi8 111 10 ) ) -RRB- cord-310304-f28tjmi8 111 11 . . . cord-310304-f28tjmi8 112 1 ACE ace NN cord-310304-f28tjmi8 112 2 I -PRON- PRP cord-310304-f28tjmi8 113 1 ( ( -LRB- cord-310304-f28tjmi8 113 2 Angiotensin angiotensin NN cord-310304-f28tjmi8 113 3 - - HYPH cord-310304-f28tjmi8 113 4 converting convert VBG cord-310304-f28tjmi8 113 5 enzyme enzyme NN cord-310304-f28tjmi8 113 6 1 1 CD cord-310304-f28tjmi8 113 7 ) ) -RRB- cord-310304-f28tjmi8 113 8 . . . cord-310304-f28tjmi8 114 1 African African NNP cord-310304-f28tjmi8 114 2 Americans Americans NNPS cord-310304-f28tjmi8 114 3 are be VBP cord-310304-f28tjmi8 114 4 two two CD cord-310304-f28tjmi8 114 5 to to TO cord-310304-f28tjmi8 114 6 three three CD cord-310304-f28tjmi8 114 7 times time NNS cord-310304-f28tjmi8 114 8 more more RBR cord-310304-f28tjmi8 114 9 likely likely JJ cord-310304-f28tjmi8 114 10 than than IN cord-310304-f28tjmi8 114 11 NHWs nhw NNS cord-310304-f28tjmi8 114 12 to to TO cord-310304-f28tjmi8 114 13 die die VB cord-310304-f28tjmi8 114 14 of of IN cord-310304-f28tjmi8 114 15 preventable preventable JJ cord-310304-f28tjmi8 114 16 CVD CVD NNP cord-310304-f28tjmi8 114 17 and and CC cord-310304-f28tjmi8 114 18 stroke stroke VB cord-310304-f28tjmi8 114 19 even even RB cord-310304-f28tjmi8 114 20 when when WRB cord-310304-f28tjmi8 114 21 accounting account VBG cord-310304-f28tjmi8 114 22 for for IN cord-310304-f28tjmi8 114 23 the the DT cord-310304-f28tjmi8 114 24 general general JJ cord-310304-f28tjmi8 114 25 decline decline NN cord-310304-f28tjmi8 114 26 in in IN cord-310304-f28tjmi8 114 27 CVD CVD NNP cord-310304-f28tjmi8 114 28 mortality mortality NN cord-310304-f28tjmi8 114 29 [ [ -LRB- cord-310304-f28tjmi8 114 30 56 56 CD cord-310304-f28tjmi8 114 31 ] ] -RRB- cord-310304-f28tjmi8 114 32 . . . cord-310304-f28tjmi8 115 1 From from IN cord-310304-f28tjmi8 115 2 2011 2011 CD cord-310304-f28tjmi8 115 3 - - SYM cord-310304-f28tjmi8 115 4 2014 2014 CD cord-310304-f28tjmi8 115 5 , , , cord-310304-f28tjmi8 115 6 a a DT cord-310304-f28tjmi8 115 7 study study NN cord-310304-f28tjmi8 115 8 found find VBD cord-310304-f28tjmi8 115 9 that that IN cord-310304-f28tjmi8 115 10 the the DT cord-310304-f28tjmi8 115 11 prevalence prevalence NN cord-310304-f28tjmi8 115 12 of of IN cord-310304-f28tjmi8 115 13 hypertension hypertension NN cord-310304-f28tjmi8 115 14 among among IN cord-310304-f28tjmi8 115 15 AA AA NNP cord-310304-f28tjmi8 115 16 adults adult NNS cord-310304-f28tjmi8 115 17 ( ( -LRB- cord-310304-f28tjmi8 115 18 41.2 41.2 CD cord-310304-f28tjmi8 115 19 % % NN cord-310304-f28tjmi8 115 20 ) ) -RRB- cord-310304-f28tjmi8 115 21 was be VBD cord-310304-f28tjmi8 115 22 higher high JJR cord-310304-f28tjmi8 115 23 than than IN cord-310304-f28tjmi8 115 24 among among IN cord-310304-f28tjmi8 115 25 NHW NHW NNP cord-310304-f28tjmi8 115 26 ( ( -LRB- cord-310304-f28tjmi8 115 27 28.0 28.0 CD cord-310304-f28tjmi8 115 28 % % NN cord-310304-f28tjmi8 115 29 ) ) -RRB- cord-310304-f28tjmi8 115 30 , , , cord-310304-f28tjmi8 115 31 NHW NHW NNP cord-310304-f28tjmi8 115 32 ( ( -LRB- cord-310304-f28tjmi8 115 33 24.9 24.9 CD cord-310304-f28tjmi8 115 34 % % NN cord-310304-f28tjmi8 115 35 ) ) -RRB- cord-310304-f28tjmi8 115 36 , , , cord-310304-f28tjmi8 115 37 and and CC cord-310304-f28tjmi8 115 38 Hispanic hispanic JJ cord-310304-f28tjmi8 115 39 ( ( -LRB- cord-310304-f28tjmi8 115 40 25.9 25.9 CD cord-310304-f28tjmi8 115 41 % % NN cord-310304-f28tjmi8 115 42 ) ) -RRB- cord-310304-f28tjmi8 115 43 adults adult NNS cord-310304-f28tjmi8 115 44 [ [ -LRB- cord-310304-f28tjmi8 115 45 57 57 CD cord-310304-f28tjmi8 115 46 ] ] -RRB- cord-310304-f28tjmi8 115 47 . . . cord-310304-f28tjmi8 116 1 Medication medication NN cord-310304-f28tjmi8 116 2 non non JJ cord-310304-f28tjmi8 116 3 - - JJ cord-310304-f28tjmi8 116 4 adherence adherence NN cord-310304-f28tjmi8 116 5 is be VBZ cord-310304-f28tjmi8 116 6 one one CD cord-310304-f28tjmi8 116 7 of of IN cord-310304-f28tjmi8 116 8 the the DT cord-310304-f28tjmi8 116 9 greatest great JJS cord-310304-f28tjmi8 116 10 challenges challenge NNS cord-310304-f28tjmi8 116 11 to to IN cord-310304-f28tjmi8 116 12 reducing reduce VBG cord-310304-f28tjmi8 116 13 health health NN cord-310304-f28tjmi8 116 14 disparities disparity NNS cord-310304-f28tjmi8 116 15 associated associate VBN cord-310304-f28tjmi8 116 16 with with IN cord-310304-f28tjmi8 116 17 CVD CVD NNP cord-310304-f28tjmi8 116 18 morbidity morbidity NN cord-310304-f28tjmi8 116 19 and and CC cord-310304-f28tjmi8 116 20 mortality mortality NN cord-310304-f28tjmi8 116 21 [ [ -LRB- cord-310304-f28tjmi8 116 22 58 58 CD cord-310304-f28tjmi8 116 23 ] ] -RRB- cord-310304-f28tjmi8 116 24 . . . cord-310304-f28tjmi8 117 1 Poor poor JJ cord-310304-f28tjmi8 117 2 management management NN cord-310304-f28tjmi8 117 3 of of IN cord-310304-f28tjmi8 117 4 hypertension hypertension NN cord-310304-f28tjmi8 117 5 is be VBZ cord-310304-f28tjmi8 117 6 linked link VBN cord-310304-f28tjmi8 117 7 to to IN cord-310304-f28tjmi8 117 8 increased increase VBN cord-310304-f28tjmi8 117 9 risk risk NN cord-310304-f28tjmi8 117 10 of of IN cord-310304-f28tjmi8 117 11 CVD CVD NNP cord-310304-f28tjmi8 117 12 , , , cord-310304-f28tjmi8 117 13 stroke stroke NN cord-310304-f28tjmi8 117 14 , , , cord-310304-f28tjmi8 117 15 and and CC cord-310304-f28tjmi8 117 16 CKD CKD NNP cord-310304-f28tjmi8 117 17 ; ; : cord-310304-f28tjmi8 117 18 hypertension hypertension NN cord-310304-f28tjmi8 117 19 management management NN cord-310304-f28tjmi8 117 20 among among IN cord-310304-f28tjmi8 117 21 AAs AAs NNP cord-310304-f28tjmi8 117 22 has have VBZ cord-310304-f28tjmi8 117 23 been be VBN cord-310304-f28tjmi8 117 24 shown show VBN cord-310304-f28tjmi8 117 25 to to TO cord-310304-f28tjmi8 117 26 be be VB cord-310304-f28tjmi8 117 27 lower low JJR cord-310304-f28tjmi8 117 28 when when WRB cord-310304-f28tjmi8 117 29 compared compare VBN cord-310304-f28tjmi8 117 30 with with IN cord-310304-f28tjmi8 117 31 NHWs nhws NN cord-310304-f28tjmi8 117 32 [ [ -LRB- cord-310304-f28tjmi8 117 33 59 59 CD cord-310304-f28tjmi8 117 34 ] ] -RRB- cord-310304-f28tjmi8 117 35 . . . cord-310304-f28tjmi8 118 1 CVD CVD NNP cord-310304-f28tjmi8 118 2 is be VBZ cord-310304-f28tjmi8 118 3 a a DT cord-310304-f28tjmi8 118 4 common common JJ cord-310304-f28tjmi8 118 5 comorbidity comorbidity NN cord-310304-f28tjmi8 118 6 in in IN cord-310304-f28tjmi8 118 7 patients patient NNS cord-310304-f28tjmi8 118 8 with with IN cord-310304-f28tjmi8 118 9 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 118 10 and and CC cord-310304-f28tjmi8 118 11 is be VBZ cord-310304-f28tjmi8 118 12 associated associate VBN cord-310304-f28tjmi8 118 13 with with IN cord-310304-f28tjmi8 118 14 patients patient NNS cord-310304-f28tjmi8 118 15 who who WP cord-310304-f28tjmi8 118 16 have have VBP cord-310304-f28tjmi8 118 17 the the DT cord-310304-f28tjmi8 118 18 most most RBS cord-310304-f28tjmi8 118 19 severe severe JJ cord-310304-f28tjmi8 118 20 disease disease NN cord-310304-f28tjmi8 118 21 [ [ -LRB- cord-310304-f28tjmi8 118 22 60 60 CD cord-310304-f28tjmi8 118 23 ] ] -RRB- cord-310304-f28tjmi8 118 24 . . . cord-310304-f28tjmi8 119 1 A a DT cord-310304-f28tjmi8 119 2 recent recent JJ cord-310304-f28tjmi8 119 3 meta meta JJ cord-310304-f28tjmi8 119 4 - - HYPH cord-310304-f28tjmi8 119 5 analysis analysis NN cord-310304-f28tjmi8 119 6 of of IN cord-310304-f28tjmi8 119 7 eight eight CD cord-310304-f28tjmi8 119 8 studies study NNS cord-310304-f28tjmi8 119 9 from from IN cord-310304-f28tjmi8 119 10 China China NNP cord-310304-f28tjmi8 119 11 that that WDT cord-310304-f28tjmi8 119 12 included include VBD cord-310304-f28tjmi8 119 13 46,248 46,248 CD cord-310304-f28tjmi8 119 14 COVID-19-infected covid-19-infecte VBN cord-310304-f28tjmi8 119 15 patients patient NNS cord-310304-f28tjmi8 119 16 showed show VBD cord-310304-f28tjmi8 119 17 the the DT cord-310304-f28tjmi8 119 18 most most RBS cord-310304-f28tjmi8 119 19 prevalent prevalent JJ cord-310304-f28tjmi8 119 20 comorbidities comorbiditie NNS cord-310304-f28tjmi8 119 21 were be VBD cord-310304-f28tjmi8 119 22 hypertension hypertension NN cord-310304-f28tjmi8 119 23 ( ( -LRB- cord-310304-f28tjmi8 119 24 17 17 CD cord-310304-f28tjmi8 119 25 ± ± CD cord-310304-f28tjmi8 119 26 7 7 CD cord-310304-f28tjmi8 119 27 % % NN cord-310304-f28tjmi8 119 28 , , , cord-310304-f28tjmi8 119 29 95 95 CD cord-310304-f28tjmi8 119 30 % % NN cord-310304-f28tjmi8 119 31 confidence confidence NN cord-310304-f28tjmi8 119 32 interval interval NN cord-310304-f28tjmi8 119 33 ( ( -LRB- cord-310304-f28tjmi8 119 34 CI CI NNP cord-310304-f28tjmi8 119 35 ) ) -RRB- cord-310304-f28tjmi8 119 36 14 14 CD cord-310304-f28tjmi8 119 37 - - SYM cord-310304-f28tjmi8 119 38 22 22 CD cord-310304-f28tjmi8 119 39 % % NN cord-310304-f28tjmi8 119 40 ) ) -RRB- cord-310304-f28tjmi8 119 41 and and CC cord-310304-f28tjmi8 119 42 diabetes diabetes NN cord-310304-f28tjmi8 119 43 ( ( -LRB- cord-310304-f28tjmi8 119 44 8 8 CD cord-310304-f28tjmi8 119 45 ± ± CD cord-310304-f28tjmi8 119 46 6 6 CD cord-310304-f28tjmi8 119 47 % % NN cord-310304-f28tjmi8 119 48 , , , cord-310304-f28tjmi8 119 49 95 95 CD cord-310304-f28tjmi8 119 50 % % NN cord-310304-f28tjmi8 119 51 CI CI NNP cord-310304-f28tjmi8 119 52 6 6 CD cord-310304-f28tjmi8 119 53 - - SYM cord-310304-f28tjmi8 119 54 11 11 CD cord-310304-f28tjmi8 119 55 % % NN cord-310304-f28tjmi8 119 56 ) ) -RRB- cord-310304-f28tjmi8 119 57 , , , cord-310304-f28tjmi8 119 58 followed follow VBN cord-310304-f28tjmi8 119 59 by by IN cord-310304-f28tjmi8 119 60 CVDs cvd NNS cord-310304-f28tjmi8 119 61 ( ( -LRB- cord-310304-f28tjmi8 119 62 5 5 CD cord-310304-f28tjmi8 119 63 ± ± CD cord-310304-f28tjmi8 119 64 4 4 CD cord-310304-f28tjmi8 119 65 % % NN cord-310304-f28tjmi8 119 66 , , , cord-310304-f28tjmi8 119 67 95 95 CD cord-310304-f28tjmi8 119 68 % % NN cord-310304-f28tjmi8 119 69 CI CI NNP cord-310304-f28tjmi8 119 70 4 4 CD cord-310304-f28tjmi8 119 71 - - SYM cord-310304-f28tjmi8 119 72 7 7 CD cord-310304-f28tjmi8 119 73 % % NN cord-310304-f28tjmi8 119 74 ) ) -RRB- cord-310304-f28tjmi8 119 75 [ [ -LRB- cord-310304-f28tjmi8 119 76 61 61 CD cord-310304-f28tjmi8 119 77 ] ] -RRB- cord-310304-f28tjmi8 119 78 . . . cord-310304-f28tjmi8 120 1 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 120 2 interacts interact VBZ cord-310304-f28tjmi8 120 3 with with IN cord-310304-f28tjmi8 120 4 the the DT cord-310304-f28tjmi8 120 5 cardiovascular cardiovascular JJ cord-310304-f28tjmi8 120 6 system system NN cord-310304-f28tjmi8 120 7 , , , cord-310304-f28tjmi8 120 8 inducing induce VBG cord-310304-f28tjmi8 120 9 myocardial myocardial JJ cord-310304-f28tjmi8 120 10 injury injury NN cord-310304-f28tjmi8 120 11 . . . cord-310304-f28tjmi8 121 1 Patients patient NNS cord-310304-f28tjmi8 121 2 with with IN cord-310304-f28tjmi8 121 3 advanced advanced JJ cord-310304-f28tjmi8 121 4 age age NN cord-310304-f28tjmi8 121 5 and and CC cord-310304-f28tjmi8 121 6 elevated elevated JJ cord-310304-f28tjmi8 121 7 troponin troponin NN cord-310304-f28tjmi8 121 8 I -PRON- PRP cord-310304-f28tjmi8 121 9 levels level NNS cord-310304-f28tjmi8 121 10 have have VBP cord-310304-f28tjmi8 121 11 abnormal abnormal JJ cord-310304-f28tjmi8 121 12 echocardiograms echocardiogram NNS cord-310304-f28tjmi8 121 13 and and CC cord-310304-f28tjmi8 121 14 are be VBP cord-310304-f28tjmi8 121 15 at at IN cord-310304-f28tjmi8 121 16 the the DT cord-310304-f28tjmi8 121 17 greatest great JJS cord-310304-f28tjmi8 121 18 risk risk NN cord-310304-f28tjmi8 121 19 for for IN cord-310304-f28tjmi8 121 20 developing develop VBG cord-310304-f28tjmi8 121 21 more more RBR cord-310304-f28tjmi8 121 22 severe severe JJ cord-310304-f28tjmi8 121 23 COVID-19 covid-19 JJ cord-310304-f28tjmi8 121 24 disease disease NN cord-310304-f28tjmi8 121 25 ( ( -LRB- cord-310304-f28tjmi8 121 26 Figure figure NN cord-310304-f28tjmi8 121 27 3 3 CD cord-310304-f28tjmi8 121 28 ) ) -RRB- cord-310304-f28tjmi8 121 29 . . . cord-310304-f28tjmi8 122 1 These these DT cord-310304-f28tjmi8 122 2 patients patient NNS cord-310304-f28tjmi8 122 3 have have VBP cord-310304-f28tjmi8 122 4 been be VBN cord-310304-f28tjmi8 122 5 shown show VBN cord-310304-f28tjmi8 122 6 to to TO cord-310304-f28tjmi8 122 7 have have VB cord-310304-f28tjmi8 122 8 increased increase VBN cord-310304-f28tjmi8 122 9 blood blood NN cord-310304-f28tjmi8 122 10 levels level NNS cord-310304-f28tjmi8 122 11 of of IN cord-310304-f28tjmi8 122 12 interleukin-6 interleukin-6 NNP cord-310304-f28tjmi8 122 13 ( ( -LRB- cord-310304-f28tjmi8 122 14 IL-6 IL-6 NNP cord-310304-f28tjmi8 122 15 ) ) -RRB- cord-310304-f28tjmi8 122 16 , , , cord-310304-f28tjmi8 122 17 ferritin ferritin NN cord-310304-f28tjmi8 122 18 , , , cord-310304-f28tjmi8 122 19 Lactic lactic JJ cord-310304-f28tjmi8 122 20 Acid acid NN cord-310304-f28tjmi8 122 21 Dehydrogenase Dehydrogenase NNP cord-310304-f28tjmi8 122 22 ( ( -LRB- cord-310304-f28tjmi8 122 23 LDH LDH NNP cord-310304-f28tjmi8 122 24 ) ) -RRB- cord-310304-f28tjmi8 122 25 , , , cord-310304-f28tjmi8 122 26 and and CC cord-310304-f28tjmi8 122 27 fibrin fibrin NN cord-310304-f28tjmi8 122 28 degradation degradation NN cord-310304-f28tjmi8 122 29 product product NN cord-310304-f28tjmi8 122 30 ( ( -LRB- cord-310304-f28tjmi8 122 31 D d NN cord-310304-f28tjmi8 122 32 - - HYPH cord-310304-f28tjmi8 122 33 dimer dimer NN cord-310304-f28tjmi8 122 34 ) ) -RRB- cord-310304-f28tjmi8 122 35 , , , cord-310304-f28tjmi8 122 36 which which WDT cord-310304-f28tjmi8 122 37 are be VBP cord-310304-f28tjmi8 122 38 associated associate VBN cord-310304-f28tjmi8 122 39 with with IN cord-310304-f28tjmi8 122 40 the the DT cord-310304-f28tjmi8 122 41 cytokine cytokine NN cord-310304-f28tjmi8 122 42 storm storm NN cord-310304-f28tjmi8 122 43 that that WDT cord-310304-f28tjmi8 122 44 likely likely RB cord-310304-f28tjmi8 122 45 would would MD cord-310304-f28tjmi8 122 46 contribute contribute VB cord-310304-f28tjmi8 122 47 to to IN cord-310304-f28tjmi8 122 48 cardiac cardiac JJ cord-310304-f28tjmi8 122 49 injury injury NN cord-310304-f28tjmi8 122 50 ( ( -LRB- cord-310304-f28tjmi8 122 51 Figure figure NN cord-310304-f28tjmi8 122 52 3 3 CD cord-310304-f28tjmi8 122 53 ) ) -RRB- cord-310304-f28tjmi8 122 54 . . . cord-310304-f28tjmi8 123 1 For for IN cord-310304-f28tjmi8 123 2 patients patient NNS cord-310304-f28tjmi8 123 3 with with IN cord-310304-f28tjmi8 123 4 cardiac cardiac JJ cord-310304-f28tjmi8 123 5 insufficiency insufficiency NN cord-310304-f28tjmi8 123 6 who who WP cord-310304-f28tjmi8 123 7 have have VBP cord-310304-f28tjmi8 123 8 underlying underlying JJ cord-310304-f28tjmi8 123 9 heart heart NN cord-310304-f28tjmi8 123 10 disease disease NN cord-310304-f28tjmi8 123 11 , , , cord-310304-f28tjmi8 123 12 SARS SARS NNP cord-310304-f28tjmi8 123 13 - - HYPH cord-310304-f28tjmi8 123 14 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 123 15 infection infection NN cord-310304-f28tjmi8 123 16 may may MD cord-310304-f28tjmi8 123 17 lead lead VB cord-310304-f28tjmi8 123 18 to to IN cord-310304-f28tjmi8 123 19 adverse adverse JJ cord-310304-f28tjmi8 123 20 clinical clinical JJ cord-310304-f28tjmi8 123 21 disease disease NN cord-310304-f28tjmi8 123 22 and and CC cord-310304-f28tjmi8 123 23 death death NN cord-310304-f28tjmi8 123 24 . . . cord-310304-f28tjmi8 124 1 Aging age VBG cord-310304-f28tjmi8 124 2 , , , cord-310304-f28tjmi8 124 3 ACE2 ACE2 NNP cord-310304-f28tjmi8 124 4 levels level NNS cord-310304-f28tjmi8 124 5 , , , cord-310304-f28tjmi8 124 6 waning wane VBG cord-310304-f28tjmi8 124 7 of of IN cord-310304-f28tjmi8 124 8 the the DT cord-310304-f28tjmi8 124 9 immune immune JJ cord-310304-f28tjmi8 124 10 response response NN cord-310304-f28tjmi8 124 11 , , , cord-310304-f28tjmi8 124 12 and and CC cord-310304-f28tjmi8 124 13 host host NN cord-310304-f28tjmi8 124 14 factors factor NNS cord-310304-f28tjmi8 124 15 that that WDT cord-310304-f28tjmi8 124 16 become become VBP cord-310304-f28tjmi8 124 17 pronounced pronounced JJ cord-310304-f28tjmi8 124 18 in in IN cord-310304-f28tjmi8 124 19 patients patient NNS cord-310304-f28tjmi8 124 20 with with IN cord-310304-f28tjmi8 124 21 CVD CVD NNP cord-310304-f28tjmi8 124 22 have have VBP cord-310304-f28tjmi8 124 23 been be VBN cord-310304-f28tjmi8 124 24 considered consider VBN cord-310304-f28tjmi8 124 25 as as IN cord-310304-f28tjmi8 124 26 possible possible JJ cord-310304-f28tjmi8 124 27 explanations explanation NNS cord-310304-f28tjmi8 124 28 for for IN cord-310304-f28tjmi8 124 29 the the DT cord-310304-f28tjmi8 124 30 severe severe JJ cord-310304-f28tjmi8 124 31 disease disease NN cord-310304-f28tjmi8 124 32 course course NN cord-310304-f28tjmi8 124 33 observed observe VBD cord-310304-f28tjmi8 124 34 in in IN cord-310304-f28tjmi8 124 35 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 124 36 patients patient NNS cord-310304-f28tjmi8 124 37 . . . cord-310304-f28tjmi8 125 1 In in IN cord-310304-f28tjmi8 125 2 a a DT cord-310304-f28tjmi8 125 3 study study NN cord-310304-f28tjmi8 125 4 in in IN cord-310304-f28tjmi8 125 5 Wuhan Wuhan NNP cord-310304-f28tjmi8 125 6 , , , cord-310304-f28tjmi8 125 7 China China NNP cord-310304-f28tjmi8 125 8 , , , cord-310304-f28tjmi8 125 9 which which WDT cord-310304-f28tjmi8 125 10 included include VBD cord-310304-f28tjmi8 125 11 138 138 CD cord-310304-f28tjmi8 125 12 COVID-19 covid-19 CD cord-310304-f28tjmi8 125 13 patients patient NNS cord-310304-f28tjmi8 125 14 , , , cord-310304-f28tjmi8 125 15 researchers researcher NNS cord-310304-f28tjmi8 125 16 observed observe VBD cord-310304-f28tjmi8 125 17 laboratory laboratory NN cord-310304-f28tjmi8 125 18 evidence evidence NN cord-310304-f28tjmi8 125 19 of of IN cord-310304-f28tjmi8 125 20 cardiac cardiac JJ cord-310304-f28tjmi8 125 21 injury injury NN cord-310304-f28tjmi8 125 22 indicated indicate VBN cord-310304-f28tjmi8 125 23 by by IN cord-310304-f28tjmi8 125 24 elevated elevated JJ cord-310304-f28tjmi8 125 25 troponin troponin NN cord-310304-f28tjmi8 125 26 I -PRON- PRP cord-310304-f28tjmi8 125 27 levels level NNS cord-310304-f28tjmi8 125 28 , , , cord-310304-f28tjmi8 125 29 as as RB cord-310304-f28tjmi8 125 30 well well RB cord-310304-f28tjmi8 125 31 as as IN cord-310304-f28tjmi8 125 32 abnormal abnormal JJ cord-310304-f28tjmi8 125 33 echocardiograms echocardiogram NNS cord-310304-f28tjmi8 125 34 in in IN cord-310304-f28tjmi8 125 35 7.2 7.2 CD cord-310304-f28tjmi8 125 36 % % NN cord-310304-f28tjmi8 125 37 of of IN cord-310304-f28tjmi8 125 38 patients patient NNS cord-310304-f28tjmi8 125 39 ( ( -LRB- cord-310304-f28tjmi8 125 40 10 10 CD cord-310304-f28tjmi8 125 41 ) ) -RRB- cord-310304-f28tjmi8 125 42 overall overall NN cord-310304-f28tjmi8 125 43 , , , cord-310304-f28tjmi8 125 44 and and CC cord-310304-f28tjmi8 125 45 22 22 CD cord-310304-f28tjmi8 125 46 % % NN cord-310304-f28tjmi8 125 47 ( ( -LRB- cord-310304-f28tjmi8 125 48 30 30 CD cord-310304-f28tjmi8 125 49 ) ) -RRB- cord-310304-f28tjmi8 125 50 who who WP cord-310304-f28tjmi8 125 51 required require VBD cord-310304-f28tjmi8 125 52 intensive intensive JJ cord-310304-f28tjmi8 125 53 care care NN cord-310304-f28tjmi8 125 54 unit unit NN cord-310304-f28tjmi8 125 55 ( ( -LRB- cord-310304-f28tjmi8 125 56 ICU ICU NNP cord-310304-f28tjmi8 125 57 ) ) -RRB- cord-310304-f28tjmi8 125 58 attention attention NN cord-310304-f28tjmi8 125 59 [ [ -LRB- cord-310304-f28tjmi8 125 60 62 62 CD cord-310304-f28tjmi8 125 61 ] ] -RRB- cord-310304-f28tjmi8 125 62 . . . cord-310304-f28tjmi8 126 1 Zheng Zheng NNP cord-310304-f28tjmi8 126 2 et et NNP cord-310304-f28tjmi8 126 3 al al NNP cord-310304-f28tjmi8 126 4 . . NNP cord-310304-f28tjmi8 126 5 , , , cord-310304-f28tjmi8 126 6 reported report VBD cord-310304-f28tjmi8 126 7 that that IN cord-310304-f28tjmi8 126 8 12 12 CD cord-310304-f28tjmi8 126 9 % % NN cord-310304-f28tjmi8 126 10 of of IN cord-310304-f28tjmi8 126 11 COVID-19 covid-19 JJ cord-310304-f28tjmi8 126 12 patients patient NNS cord-310304-f28tjmi8 126 13 who who WP cord-310304-f28tjmi8 126 14 died die VBD cord-310304-f28tjmi8 126 15 without without IN cord-310304-f28tjmi8 126 16 known know VBN cord-310304-f28tjmi8 126 17 CVD CVD NNP cord-310304-f28tjmi8 126 18 risk risk NN cord-310304-f28tjmi8 126 19 clinically clinically RB cord-310304-f28tjmi8 126 20 presented present VBN cord-310304-f28tjmi8 126 21 with with IN cord-310304-f28tjmi8 126 22 elevated elevated JJ cord-310304-f28tjmi8 126 23 levels level NNS cord-310304-f28tjmi8 126 24 of of IN cord-310304-f28tjmi8 126 25 troponin troponin NN cord-310304-f28tjmi8 126 26 I -PRON- PRP cord-310304-f28tjmi8 126 27 or or CC cord-310304-f28tjmi8 126 28 cardiac cardiac JJ cord-310304-f28tjmi8 126 29 arrest arrest NN cord-310304-f28tjmi8 126 30 during during IN cord-310304-f28tjmi8 126 31 their -PRON- PRP$ cord-310304-f28tjmi8 126 32 hospitalization hospitalization NN cord-310304-f28tjmi8 126 33 [ [ -LRB- cord-310304-f28tjmi8 126 34 63 63 CD cord-310304-f28tjmi8 126 35 ] ] -RRB- cord-310304-f28tjmi8 126 36 . . . cord-310304-f28tjmi8 127 1 The the DT cord-310304-f28tjmi8 127 2 connection connection NN cord-310304-f28tjmi8 127 3 between between IN cord-310304-f28tjmi8 127 4 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 127 5 and and CC cord-310304-f28tjmi8 127 6 CVD CVD NNP cord-310304-f28tjmi8 127 7 remains remain VBZ cord-310304-f28tjmi8 127 8 unclear unclear JJ cord-310304-f28tjmi8 127 9 ; ; : cord-310304-f28tjmi8 127 10 however however RB cord-310304-f28tjmi8 127 11 , , , cord-310304-f28tjmi8 127 12 it -PRON- PRP cord-310304-f28tjmi8 127 13 has have VBZ cord-310304-f28tjmi8 127 14 been be VBN cord-310304-f28tjmi8 127 15 suggested suggest VBN cord-310304-f28tjmi8 127 16 that that IN cord-310304-f28tjmi8 127 17 direct direct JJ cord-310304-f28tjmi8 127 18 infection infection NN cord-310304-f28tjmi8 127 19 of of IN cord-310304-f28tjmi8 127 20 the the DT cord-310304-f28tjmi8 127 21 heart heart NN cord-310304-f28tjmi8 127 22 occurs occur VBZ cord-310304-f28tjmi8 127 23 via via IN cord-310304-f28tjmi8 127 24 ACE2 ACE2 NNP cord-310304-f28tjmi8 127 25 expression expression NN cord-310304-f28tjmi8 127 26 on on IN cord-310304-f28tjmi8 127 27 myocardial myocardial JJ cord-310304-f28tjmi8 127 28 tissue tissue NN cord-310304-f28tjmi8 127 29 , , , cord-310304-f28tjmi8 127 30 with with IN cord-310304-f28tjmi8 127 31 supporting support VBG cord-310304-f28tjmi8 127 32 evidence evidence NN cord-310304-f28tjmi8 127 33 in in IN cord-310304-f28tjmi8 127 34 a a DT cord-310304-f28tjmi8 127 35 murine murine JJ cord-310304-f28tjmi8 127 36 model model NN cord-310304-f28tjmi8 127 37 demonstrating demonstrate VBG cord-310304-f28tjmi8 127 38 ACE2-dependent ace2-dependent NN cord-310304-f28tjmi8 127 39 myocardial myocardial JJ cord-310304-f28tjmi8 127 40 infection infection NN cord-310304-f28tjmi8 127 41 of of IN cord-310304-f28tjmi8 127 42 SARS SARS NNP cord-310304-f28tjmi8 127 43 - - HYPH cord-310304-f28tjmi8 127 44 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 127 45 [ [ -LRB- cord-310304-f28tjmi8 127 46 64 64 CD cord-310304-f28tjmi8 127 47 ] ] -RRB- cord-310304-f28tjmi8 127 48 ( ( -LRB- cord-310304-f28tjmi8 127 49 Figure figure NN cord-310304-f28tjmi8 127 50 3 3 CD cord-310304-f28tjmi8 127 51 ) ) -RRB- cord-310304-f28tjmi8 127 52 . . . cord-310304-f28tjmi8 128 1 In in IN cord-310304-f28tjmi8 128 2 addition addition NN cord-310304-f28tjmi8 128 3 , , , cord-310304-f28tjmi8 128 4 SARS SARS NNP cord-310304-f28tjmi8 128 5 - - HYPH cord-310304-f28tjmi8 128 6 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 128 7 RNA RNA NNP cord-310304-f28tjmi8 128 8 was be VBD cord-310304-f28tjmi8 128 9 detected detect VBN cord-310304-f28tjmi8 128 10 in in IN cord-310304-f28tjmi8 128 11 heart heart NN cord-310304-f28tjmi8 128 12 tissue tissue NN cord-310304-f28tjmi8 128 13 from from IN cord-310304-f28tjmi8 128 14 35 35 CD cord-310304-f28tjmi8 128 15 % % NN cord-310304-f28tjmi8 128 16 of of IN cord-310304-f28tjmi8 128 17 patients patient NNS cord-310304-f28tjmi8 128 18 who who WP cord-310304-f28tjmi8 128 19 died die VBD cord-310304-f28tjmi8 128 20 during during IN cord-310304-f28tjmi8 128 21 the the DT cord-310304-f28tjmi8 128 22 SARS SARS NNP cord-310304-f28tjmi8 128 23 - - HYPH cord-310304-f28tjmi8 128 24 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 128 25 outbreak outbreak NN cord-310304-f28tjmi8 128 26 in in IN cord-310304-f28tjmi8 128 27 Toronto Toronto NNP cord-310304-f28tjmi8 128 28 [ [ -LRB- cord-310304-f28tjmi8 128 29 65 65 CD cord-310304-f28tjmi8 128 30 ] ] -RRB- cord-310304-f28tjmi8 128 31 . . . cord-310304-f28tjmi8 129 1 A a DT cord-310304-f28tjmi8 129 2 cytokine cytokine NN cord-310304-f28tjmi8 129 3 storm storm NN cord-310304-f28tjmi8 129 4 and and CC cord-310304-f28tjmi8 129 5 calcium calcium NN cord-310304-f28tjmi8 129 6 - - HYPH cord-310304-f28tjmi8 129 7 dependent dependent JJ cord-310304-f28tjmi8 129 8 apoptosis apoptosis NN cord-310304-f28tjmi8 129 9 of of IN cord-310304-f28tjmi8 129 10 cardiomyocytes cardiomyocyte NNS cord-310304-f28tjmi8 129 11 are be VBP cord-310304-f28tjmi8 129 12 among among IN cord-310304-f28tjmi8 129 13 other other JJ cord-310304-f28tjmi8 129 14 mechanism mechanism NN cord-310304-f28tjmi8 129 15 that that WDT cord-310304-f28tjmi8 129 16 could could MD cord-310304-f28tjmi8 129 17 link link VB cord-310304-f28tjmi8 129 18 CVD CVD NNP cord-310304-f28tjmi8 129 19 and and CC cord-310304-f28tjmi8 129 20 COVID-19 covid-19 VB cord-310304-f28tjmi8 129 21 [ [ -LRB- cord-310304-f28tjmi8 129 22 66 66 CD cord-310304-f28tjmi8 129 23 ] ] -RRB- cord-310304-f28tjmi8 130 1 ( ( -LRB- cord-310304-f28tjmi8 130 2 Figure figure NN cord-310304-f28tjmi8 130 3 3 3 CD cord-310304-f28tjmi8 130 4 ) ) -RRB- cord-310304-f28tjmi8 130 5 . . . cord-310304-f28tjmi8 131 1 ACE2-related ACE2-related NNP cord-310304-f28tjmi8 131 2 signaling signal VBG cord-310304-f28tjmi8 131 3 pathways pathway NNS cord-310304-f28tjmi8 131 4 also also RB cord-310304-f28tjmi8 131 5 may may MD cord-310304-f28tjmi8 131 6 have have VB cord-310304-f28tjmi8 131 7 a a DT cord-310304-f28tjmi8 131 8 role role NN cord-310304-f28tjmi8 131 9 in in IN cord-310304-f28tjmi8 131 10 heart heart NN cord-310304-f28tjmi8 131 11 injury injury NN cord-310304-f28tjmi8 131 12 . . . cord-310304-f28tjmi8 132 1 Heart heart NN cord-310304-f28tjmi8 132 2 transplant transplant NN cord-310304-f28tjmi8 132 3 patients patient NNS cord-310304-f28tjmi8 132 4 are be VBP cord-310304-f28tjmi8 132 5 expected expect VBN cord-310304-f28tjmi8 132 6 to to TO cord-310304-f28tjmi8 132 7 be be VB cord-310304-f28tjmi8 132 8 especially especially RB cord-310304-f28tjmi8 132 9 vulnerable vulnerable JJ cord-310304-f28tjmi8 132 10 to to IN cord-310304-f28tjmi8 132 11 SARS SARS NNP cord-310304-f28tjmi8 132 12 - - HYPH cord-310304-f28tjmi8 132 13 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 132 14 infection infection NN cord-310304-f28tjmi8 132 15 due due IN cord-310304-f28tjmi8 132 16 to to IN cord-310304-f28tjmi8 132 17 immunosuppression immunosuppression NN cord-310304-f28tjmi8 132 18 ; ; : cord-310304-f28tjmi8 132 19 however however RB cord-310304-f28tjmi8 132 20 , , , cord-310304-f28tjmi8 132 21 in in IN cord-310304-f28tjmi8 132 22 a a DT cord-310304-f28tjmi8 132 23 small small JJ cord-310304-f28tjmi8 132 24 study study NN cord-310304-f28tjmi8 132 25 performed perform VBN cord-310304-f28tjmi8 132 26 with with IN cord-310304-f28tjmi8 132 27 87 87 CD cord-310304-f28tjmi8 132 28 heart heart NN cord-310304-f28tjmi8 132 29 transplant transplant NN cord-310304-f28tjmi8 132 30 recipients recipient NNS cord-310304-f28tjmi8 132 31 in in IN cord-310304-f28tjmi8 132 32 Wuhan Wuhan NNP cord-310304-f28tjmi8 132 33 , , , cord-310304-f28tjmi8 132 34 China China NNP cord-310304-f28tjmi8 132 35 , , , cord-310304-f28tjmi8 132 36 no no DT cord-310304-f28tjmi8 132 37 evidence evidence NN cord-310304-f28tjmi8 132 38 of of IN cord-310304-f28tjmi8 132 39 a a DT cord-310304-f28tjmi8 132 40 higher high JJR cord-310304-f28tjmi8 132 41 risk risk NN cord-310304-f28tjmi8 132 42 of of IN cord-310304-f28tjmi8 132 43 infection infection NN cord-310304-f28tjmi8 132 44 with with IN cord-310304-f28tjmi8 132 45 SARS SARS NNP cord-310304-f28tjmi8 132 46 - - HYPH cord-310304-f28tjmi8 132 47 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 132 48 was be VBD cord-310304-f28tjmi8 132 49 found find VBN cord-310304-f28tjmi8 132 50 when when WRB cord-310304-f28tjmi8 132 51 precautionary precautionary JJ cord-310304-f28tjmi8 132 52 measures measure NNS cord-310304-f28tjmi8 132 53 were be VBD cord-310304-f28tjmi8 132 54 taken take VBN cord-310304-f28tjmi8 132 55 [ [ -LRB- cord-310304-f28tjmi8 132 56 67 67 CD cord-310304-f28tjmi8 132 57 ] ] -RRB- cord-310304-f28tjmi8 132 58 . . . cord-310304-f28tjmi8 133 1 Recommended recommend VBN cord-310304-f28tjmi8 133 2 guidelines guideline NNS cord-310304-f28tjmi8 133 3 reported report VBN cord-310304-f28tjmi8 133 4 as as IN cord-310304-f28tjmi8 133 5 Guidance Guidance NNP cord-310304-f28tjmi8 133 6 for for IN cord-310304-f28tjmi8 133 7 Cardiothoracic Cardiothoracic NNP cord-310304-f28tjmi8 133 8 Transplant Transplant NNP cord-310304-f28tjmi8 133 9 and and CC cord-310304-f28tjmi8 133 10 Mechanical Mechanical NNP cord-310304-f28tjmi8 133 11 Circulatory Circulatory NNP cord-310304-f28tjmi8 133 12 Support Support NNP cord-310304-f28tjmi8 133 13 Centers Centers NNPS cord-310304-f28tjmi8 133 14 regarding regard VBG cord-310304-f28tjmi8 133 15 SARS SARS NNP cord-310304-f28tjmi8 133 16 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 133 17 infection infection NN cord-310304-f28tjmi8 133 18 and and CC cord-310304-f28tjmi8 133 19 COVID-19 covid-19 NN cord-310304-f28tjmi8 133 20 have have VBP cord-310304-f28tjmi8 133 21 been be VBN cord-310304-f28tjmi8 133 22 established establish VBN cord-310304-f28tjmi8 133 23 and and CC cord-310304-f28tjmi8 133 24 must must MD cord-310304-f28tjmi8 133 25 be be VB cord-310304-f28tjmi8 133 26 followed follow VBN cord-310304-f28tjmi8 133 27 when when WRB cord-310304-f28tjmi8 133 28 performing perform VBG cord-310304-f28tjmi8 133 29 heart heart NN cord-310304-f28tjmi8 133 30 transplantation transplantation NN cord-310304-f28tjmi8 133 31 [ [ -LRB- cord-310304-f28tjmi8 133 32 68 68 CD cord-310304-f28tjmi8 133 33 ] ] -RRB- cord-310304-f28tjmi8 133 34 . . . cord-310304-f28tjmi8 134 1 It -PRON- PRP cord-310304-f28tjmi8 134 2 is be VBZ cord-310304-f28tjmi8 134 3 recommended recommend VBN cord-310304-f28tjmi8 134 4 that that IN cord-310304-f28tjmi8 134 5 patients patient NNS cord-310304-f28tjmi8 134 6 continue continue VBP cord-310304-f28tjmi8 134 7 heart heart NN cord-310304-f28tjmi8 134 8 transplantation transplantation NN cord-310304-f28tjmi8 134 9 without without IN cord-310304-f28tjmi8 134 10 changes change NNS cord-310304-f28tjmi8 134 11 in in IN cord-310304-f28tjmi8 134 12 immunosuppression immunosuppression NN cord-310304-f28tjmi8 134 13 , , , cord-310304-f28tjmi8 134 14 provided provide VBD cord-310304-f28tjmi8 134 15 the the DT cord-310304-f28tjmi8 134 16 recipient recipient NN cord-310304-f28tjmi8 134 17 has have VBZ cord-310304-f28tjmi8 134 18 not not RB cord-310304-f28tjmi8 134 19 tested test VBN cord-310304-f28tjmi8 134 20 positive positive JJ cord-310304-f28tjmi8 134 21 for for IN cord-310304-f28tjmi8 134 22 SARS SARS NNP cord-310304-f28tjmi8 134 23 - - HYPH cord-310304-f28tjmi8 134 24 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 134 25 and and CC cord-310304-f28tjmi8 134 26 has have VBZ cord-310304-f28tjmi8 134 27 not not RB cord-310304-f28tjmi8 134 28 had have VBN cord-310304-f28tjmi8 134 29 exposure exposure NN cord-310304-f28tjmi8 134 30 to to IN cord-310304-f28tjmi8 134 31 or or CC cord-310304-f28tjmi8 134 32 symptoms symptom NNS cord-310304-f28tjmi8 134 33 of of IN cord-310304-f28tjmi8 134 34 COVID-19 covid-19 CD cord-310304-f28tjmi8 134 35 in in IN cord-310304-f28tjmi8 134 36 the the DT cord-310304-f28tjmi8 134 37 prior prior JJ cord-310304-f28tjmi8 134 38 two two CD cord-310304-f28tjmi8 134 39 to to TO cord-310304-f28tjmi8 134 40 four four CD cord-310304-f28tjmi8 134 41 weeks week NNS cord-310304-f28tjmi8 134 42 [ [ -LRB- cord-310304-f28tjmi8 134 43 69 69 CD cord-310304-f28tjmi8 134 44 ] ] -RRB- cord-310304-f28tjmi8 135 1 It -PRON- PRP cord-310304-f28tjmi8 135 2 is be VBZ cord-310304-f28tjmi8 135 3 also also RB cord-310304-f28tjmi8 135 4 recommended recommend VBN cord-310304-f28tjmi8 135 5 to to TO cord-310304-f28tjmi8 135 6 avoid avoid VB cord-310304-f28tjmi8 135 7 donors donor NNS cord-310304-f28tjmi8 135 8 with with IN cord-310304-f28tjmi8 135 9 known know VBN cord-310304-f28tjmi8 135 10 or or CC cord-310304-f28tjmi8 135 11 suspected suspect VBN cord-310304-f28tjmi8 135 12 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 135 13 , , , cord-310304-f28tjmi8 135 14 and and CC cord-310304-f28tjmi8 135 15 if if IN cord-310304-f28tjmi8 135 16 donors donor NNS cord-310304-f28tjmi8 135 17 had have VBD cord-310304-f28tjmi8 135 18 COVID-19 COVID-19 VBN cord-310304-f28tjmi8 135 19 , , , cord-310304-f28tjmi8 135 20 they -PRON- PRP cord-310304-f28tjmi8 135 21 should should MD cord-310304-f28tjmi8 135 22 be be VB cord-310304-f28tjmi8 135 23 COVID-19-free COVID-19-free NNP cord-310304-f28tjmi8 135 24 ( ( -LRB- cord-310304-f28tjmi8 135 25 as as IN cord-310304-f28tjmi8 135 26 indicated indicate VBN cord-310304-f28tjmi8 135 27 by by IN cord-310304-f28tjmi8 135 28 polymerase polymerase NN cord-310304-f28tjmi8 135 29 chain chain NN cord-310304-f28tjmi8 135 30 reaction reaction NN cord-310304-f28tjmi8 135 31 ) ) -RRB- cord-310304-f28tjmi8 135 32 for for IN cord-310304-f28tjmi8 135 33 at at RB cord-310304-f28tjmi8 135 34 least least RBS cord-310304-f28tjmi8 135 35 14 14 CD cord-310304-f28tjmi8 135 36 days day NNS cord-310304-f28tjmi8 135 37 , , , cord-310304-f28tjmi8 135 38 owing owe VBG cord-310304-f28tjmi8 135 39 to to IN cord-310304-f28tjmi8 135 40 the the DT cord-310304-f28tjmi8 135 41 incubation incubation NN cord-310304-f28tjmi8 135 42 period period NN cord-310304-f28tjmi8 135 43 of~5 of~5 NN cord-310304-f28tjmi8 135 44 days day NNS cord-310304-f28tjmi8 135 45 and and CC cord-310304-f28tjmi8 135 46 onset onset NN cord-310304-f28tjmi8 135 47 of of IN cord-310304-f28tjmi8 135 48 symptoms symptom NNS cord-310304-f28tjmi8 135 49 in~11.5 in~11.5 NNS cord-310304-f28tjmi8 136 1 days day NNS cord-310304-f28tjmi8 136 2 [ [ -LRB- cord-310304-f28tjmi8 136 3 70 70 CD cord-310304-f28tjmi8 136 4 ] ] -RRB- cord-310304-f28tjmi8 136 5 . . . cord-310304-f28tjmi8 137 1 Hypothetical hypothetical JJ cord-310304-f28tjmi8 137 2 model model NN cord-310304-f28tjmi8 137 3 of of IN cord-310304-f28tjmi8 137 4 patients patient NNS cord-310304-f28tjmi8 137 5 with with IN cord-310304-f28tjmi8 137 6 CVD CVD NNP cord-310304-f28tjmi8 137 7 and and CC cord-310304-f28tjmi8 137 8 increased increase VBN cord-310304-f28tjmi8 137 9 risk risk NN cord-310304-f28tjmi8 137 10 for for IN cord-310304-f28tjmi8 137 11 complications complication NNS cord-310304-f28tjmi8 137 12 due due JJ cord-310304-f28tjmi8 137 13 to to IN cord-310304-f28tjmi8 137 14 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 137 15 . . . cord-310304-f28tjmi8 137 16 CVD cvd NN cord-310304-f28tjmi8 137 17 patients patient NNS cord-310304-f28tjmi8 137 18 with with IN cord-310304-f28tjmi8 137 19 advanced advanced JJ cord-310304-f28tjmi8 137 20 age age NN cord-310304-f28tjmi8 137 21 and and CC cord-310304-f28tjmi8 137 22 elevated elevated JJ cord-310304-f28tjmi8 137 23 troponin troponin NN cord-310304-f28tjmi8 137 24 I -PRON- PRP cord-310304-f28tjmi8 137 25 levels level NNS cord-310304-f28tjmi8 137 26 , , , cord-310304-f28tjmi8 137 27 and and CC cord-310304-f28tjmi8 137 28 who who WP cord-310304-f28tjmi8 137 29 have have VBP cord-310304-f28tjmi8 137 30 abnormal abnormal JJ cord-310304-f28tjmi8 137 31 echocardiograms echocardiogram NNS cord-310304-f28tjmi8 137 32 , , , cord-310304-f28tjmi8 137 33 are be VBP cord-310304-f28tjmi8 137 34 at at IN cord-310304-f28tjmi8 137 35 high high JJ cord-310304-f28tjmi8 137 36 risk risk NN cord-310304-f28tjmi8 137 37 for for IN cord-310304-f28tjmi8 137 38 developing develop VBG cord-310304-f28tjmi8 137 39 more more RBR cord-310304-f28tjmi8 137 40 severe severe JJ cord-310304-f28tjmi8 137 41 COVID-19 covid-19 JJ cord-310304-f28tjmi8 137 42 disease disease NN cord-310304-f28tjmi8 137 43 . . . cord-310304-f28tjmi8 138 1 These these DT cord-310304-f28tjmi8 138 2 patients patient NNS cord-310304-f28tjmi8 138 3 have have VBP cord-310304-f28tjmi8 138 4 been be VBN cord-310304-f28tjmi8 138 5 shown show VBN cord-310304-f28tjmi8 138 6 to to TO cord-310304-f28tjmi8 138 7 have have VB cord-310304-f28tjmi8 138 8 increased increase VBN cord-310304-f28tjmi8 138 9 blood blood NN cord-310304-f28tjmi8 138 10 levels level NNS cord-310304-f28tjmi8 138 11 of of IN cord-310304-f28tjmi8 138 12 IL-6 IL-6 NNP cord-310304-f28tjmi8 138 13 , , , cord-310304-f28tjmi8 138 14 ferritin ferritin NN cord-310304-f28tjmi8 138 15 , , , cord-310304-f28tjmi8 138 16 LDH LDH NNP cord-310304-f28tjmi8 138 17 , , , cord-310304-f28tjmi8 138 18 and and CC cord-310304-f28tjmi8 138 19 D d NN cord-310304-f28tjmi8 138 20 - - HYPH cord-310304-f28tjmi8 138 21 dimer dimer NN cord-310304-f28tjmi8 138 22 , , , cord-310304-f28tjmi8 138 23 which which WDT cord-310304-f28tjmi8 138 24 are be VBP cord-310304-f28tjmi8 138 25 associated associate VBN cord-310304-f28tjmi8 138 26 with with IN cord-310304-f28tjmi8 138 27 the the DT cord-310304-f28tjmi8 138 28 cytokine cytokine NN cord-310304-f28tjmi8 138 29 storm storm NN cord-310304-f28tjmi8 138 30 that that WDT cord-310304-f28tjmi8 138 31 likely likely RB cord-310304-f28tjmi8 138 32 would would MD cord-310304-f28tjmi8 138 33 contribute contribute VB cord-310304-f28tjmi8 138 34 to to IN cord-310304-f28tjmi8 138 35 cardiac cardiac JJ cord-310304-f28tjmi8 138 36 injury injury NN cord-310304-f28tjmi8 138 37 . . . cord-310304-f28tjmi8 139 1 High high JJ cord-310304-f28tjmi8 139 2 levels level NNS cord-310304-f28tjmi8 139 3 of of IN cord-310304-f28tjmi8 139 4 ACE2 ACE2 NNP cord-310304-f28tjmi8 139 5 are be VBP cord-310304-f28tjmi8 139 6 known know VBN cord-310304-f28tjmi8 139 7 to to TO cord-310304-f28tjmi8 139 8 be be VB cord-310304-f28tjmi8 139 9 expressed express VBN cord-310304-f28tjmi8 139 10 on on IN cord-310304-f28tjmi8 139 11 cardiomyocytes cardiomyocyte NNS cord-310304-f28tjmi8 139 12 that that WDT cord-310304-f28tjmi8 139 13 could could MD cord-310304-f28tjmi8 139 14 result result VB cord-310304-f28tjmi8 139 15 in in IN cord-310304-f28tjmi8 139 16 direct direct JJ cord-310304-f28tjmi8 139 17 infection infection NN cord-310304-f28tjmi8 139 18 of of IN cord-310304-f28tjmi8 139 19 heart heart NN cord-310304-f28tjmi8 139 20 tissue tissue NN cord-310304-f28tjmi8 139 21 by by IN cord-310304-f28tjmi8 139 22 SARS SARS NNP cord-310304-f28tjmi8 139 23 - - HYPH cord-310304-f28tjmi8 139 24 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 139 25 , , , cord-310304-f28tjmi8 139 26 which which WDT cord-310304-f28tjmi8 139 27 is be VBZ cord-310304-f28tjmi8 139 28 thought think VBN cord-310304-f28tjmi8 139 29 to to TO cord-310304-f28tjmi8 139 30 induce induce VB cord-310304-f28tjmi8 139 31 hypoxia hypoxia NN cord-310304-f28tjmi8 139 32 leading lead VBG cord-310304-f28tjmi8 139 33 to to TO cord-310304-f28tjmi8 139 34 increase increase VB cord-310304-f28tjmi8 139 35 calcium calcium NN cord-310304-f28tjmi8 139 36 levels level NNS cord-310304-f28tjmi8 139 37 resulting result VBG cord-310304-f28tjmi8 139 38 in in IN cord-310304-f28tjmi8 139 39 apoptosis apoptosis NN cord-310304-f28tjmi8 139 40 and and CC cord-310304-f28tjmi8 139 41 death death NN cord-310304-f28tjmi8 139 42 of of IN cord-310304-f28tjmi8 139 43 cardiomyocytes cardiomyocyte NNS cord-310304-f28tjmi8 139 44 ; ; : cord-310304-f28tjmi8 139 45 this this DT cord-310304-f28tjmi8 139 46 likely likely RB cord-310304-f28tjmi8 139 47 would would MD cord-310304-f28tjmi8 139 48 contribute contribute VB cord-310304-f28tjmi8 139 49 to to IN cord-310304-f28tjmi8 139 50 myocardial myocardial JJ cord-310304-f28tjmi8 139 51 injury injury NN cord-310304-f28tjmi8 139 52 . . . cord-310304-f28tjmi8 140 1 Heart heart NN cord-310304-f28tjmi8 140 2 transplant transplant NN cord-310304-f28tjmi8 140 3 patients patient NNS cord-310304-f28tjmi8 140 4 are be VBP cord-310304-f28tjmi8 140 5 expected expect VBN cord-310304-f28tjmi8 140 6 to to TO cord-310304-f28tjmi8 140 7 be be VB cord-310304-f28tjmi8 140 8 especially especially RB cord-310304-f28tjmi8 140 9 vulnerable vulnerable JJ cord-310304-f28tjmi8 140 10 to to IN cord-310304-f28tjmi8 140 11 SARS SARS NNP cord-310304-f28tjmi8 140 12 - - HYPH cord-310304-f28tjmi8 140 13 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 140 14 infection infection NN cord-310304-f28tjmi8 140 15 due due IN cord-310304-f28tjmi8 140 16 to to IN cord-310304-f28tjmi8 140 17 immunosuppression immunosuppression NN cord-310304-f28tjmi8 140 18 ; ; : cord-310304-f28tjmi8 140 19 however however RB cord-310304-f28tjmi8 140 20 , , , cord-310304-f28tjmi8 140 21 in in IN cord-310304-f28tjmi8 140 22 a a DT cord-310304-f28tjmi8 140 23 small small JJ cord-310304-f28tjmi8 140 24 study study NN cord-310304-f28tjmi8 140 25 performed perform VBN cord-310304-f28tjmi8 140 26 with with IN cord-310304-f28tjmi8 140 27 87 87 CD cord-310304-f28tjmi8 140 28 heart heart NN cord-310304-f28tjmi8 140 29 transplant transplant NN cord-310304-f28tjmi8 140 30 recipients recipient NNS cord-310304-f28tjmi8 140 31 in in IN cord-310304-f28tjmi8 140 32 Wuhan Wuhan NNP cord-310304-f28tjmi8 140 33 , , , cord-310304-f28tjmi8 140 34 China China NNP cord-310304-f28tjmi8 140 35 , , , cord-310304-f28tjmi8 140 36 no no DT cord-310304-f28tjmi8 140 37 evidence evidence NN cord-310304-f28tjmi8 140 38 of of IN cord-310304-f28tjmi8 140 39 a a DT cord-310304-f28tjmi8 140 40 higher high JJR cord-310304-f28tjmi8 140 41 risk risk NN cord-310304-f28tjmi8 140 42 of of IN cord-310304-f28tjmi8 140 43 infection infection NN cord-310304-f28tjmi8 140 44 with with IN cord-310304-f28tjmi8 140 45 SARS SARS NNP cord-310304-f28tjmi8 140 46 - - HYPH cord-310304-f28tjmi8 140 47 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 140 48 was be VBD cord-310304-f28tjmi8 140 49 found find VBN cord-310304-f28tjmi8 140 50 when when WRB cord-310304-f28tjmi8 140 51 precautionary precautionary JJ cord-310304-f28tjmi8 140 52 measures measure NNS cord-310304-f28tjmi8 140 53 were be VBD cord-310304-f28tjmi8 140 54 taken take VBN cord-310304-f28tjmi8 140 55 [ [ -LRB- cord-310304-f28tjmi8 140 56 67 67 CD cord-310304-f28tjmi8 140 57 ] ] -RRB- cord-310304-f28tjmi8 140 58 . . . cord-310304-f28tjmi8 141 1 Recommended recommend VBN cord-310304-f28tjmi8 141 2 guidelines guideline NNS cord-310304-f28tjmi8 141 3 reported report VBN cord-310304-f28tjmi8 141 4 as as IN cord-310304-f28tjmi8 141 5 Guidance Guidance NNP cord-310304-f28tjmi8 141 6 for for IN cord-310304-f28tjmi8 141 7 Cardiothoracic Cardiothoracic NNP cord-310304-f28tjmi8 141 8 Transplant Transplant NNP cord-310304-f28tjmi8 141 9 and and CC cord-310304-f28tjmi8 141 10 Mechanical Mechanical NNP cord-310304-f28tjmi8 141 11 Circulatory Circulatory NNP cord-310304-f28tjmi8 141 12 Support Support NNP cord-310304-f28tjmi8 141 13 Centers Centers NNPS cord-310304-f28tjmi8 141 14 regarding regard VBG cord-310304-f28tjmi8 141 15 SARS SARS NNP cord-310304-f28tjmi8 141 16 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 141 17 infection infection NN cord-310304-f28tjmi8 141 18 and and CC cord-310304-f28tjmi8 141 19 COVID-19 covid-19 NN cord-310304-f28tjmi8 141 20 have have VBP cord-310304-f28tjmi8 141 21 been be VBN cord-310304-f28tjmi8 141 22 established establish VBN cord-310304-f28tjmi8 141 23 and and CC cord-310304-f28tjmi8 141 24 must must MD cord-310304-f28tjmi8 141 25 be be VB cord-310304-f28tjmi8 141 26 followed follow VBN cord-310304-f28tjmi8 141 27 when when WRB cord-310304-f28tjmi8 141 28 performing perform VBG cord-310304-f28tjmi8 141 29 heart heart NN cord-310304-f28tjmi8 141 30 transplantation transplantation NN cord-310304-f28tjmi8 141 31 [ [ -LRB- cord-310304-f28tjmi8 141 32 68 68 CD cord-310304-f28tjmi8 141 33 ] ] -RRB- cord-310304-f28tjmi8 141 34 . . . cord-310304-f28tjmi8 142 1 It -PRON- PRP cord-310304-f28tjmi8 142 2 is be VBZ cord-310304-f28tjmi8 142 3 recommended recommend VBN cord-310304-f28tjmi8 142 4 that that IN cord-310304-f28tjmi8 142 5 patients patient NNS cord-310304-f28tjmi8 142 6 continue continue VBP cord-310304-f28tjmi8 142 7 heart heart NN cord-310304-f28tjmi8 142 8 transplantation transplantation NN cord-310304-f28tjmi8 142 9 without without IN cord-310304-f28tjmi8 142 10 changes change NNS cord-310304-f28tjmi8 142 11 in in IN cord-310304-f28tjmi8 142 12 immunosuppression immunosuppression NN cord-310304-f28tjmi8 142 13 , , , cord-310304-f28tjmi8 142 14 provided provide VBD cord-310304-f28tjmi8 142 15 the the DT cord-310304-f28tjmi8 142 16 recipient recipient NN cord-310304-f28tjmi8 142 17 has have VBZ cord-310304-f28tjmi8 142 18 not not RB cord-310304-f28tjmi8 142 19 tested test VBN cord-310304-f28tjmi8 142 20 positive positive JJ cord-310304-f28tjmi8 142 21 for for IN cord-310304-f28tjmi8 142 22 SARS SARS NNP cord-310304-f28tjmi8 142 23 - - HYPH cord-310304-f28tjmi8 142 24 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 142 25 and and CC cord-310304-f28tjmi8 142 26 has have VBZ cord-310304-f28tjmi8 142 27 not not RB cord-310304-f28tjmi8 142 28 had have VBN cord-310304-f28tjmi8 142 29 exposure exposure NN cord-310304-f28tjmi8 142 30 to to IN cord-310304-f28tjmi8 142 31 or or CC cord-310304-f28tjmi8 142 32 symptoms symptom NNS cord-310304-f28tjmi8 142 33 of of IN cord-310304-f28tjmi8 142 34 COVID-19 covid-19 CD cord-310304-f28tjmi8 142 35 in in IN cord-310304-f28tjmi8 142 36 the the DT cord-310304-f28tjmi8 142 37 prior prior JJ cord-310304-f28tjmi8 142 38 two two CD cord-310304-f28tjmi8 142 39 to to TO cord-310304-f28tjmi8 142 40 four four CD cord-310304-f28tjmi8 142 41 weeks week NNS cord-310304-f28tjmi8 142 42 [ [ -LRB- cord-310304-f28tjmi8 142 43 69 69 CD cord-310304-f28tjmi8 142 44 ] ] -RRB- cord-310304-f28tjmi8 143 1 It -PRON- PRP cord-310304-f28tjmi8 143 2 is be VBZ cord-310304-f28tjmi8 143 3 also also RB cord-310304-f28tjmi8 143 4 recommended recommend VBN cord-310304-f28tjmi8 143 5 to to TO cord-310304-f28tjmi8 143 6 avoid avoid VB cord-310304-f28tjmi8 143 7 donors donor NNS cord-310304-f28tjmi8 143 8 with with IN cord-310304-f28tjmi8 143 9 known know VBN cord-310304-f28tjmi8 143 10 or or CC cord-310304-f28tjmi8 143 11 suspected suspect VBN cord-310304-f28tjmi8 143 12 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 143 13 , , , cord-310304-f28tjmi8 143 14 and and CC cord-310304-f28tjmi8 143 15 if if IN cord-310304-f28tjmi8 143 16 donors donor NNS cord-310304-f28tjmi8 143 17 had have VBD cord-310304-f28tjmi8 143 18 COVID-19 COVID-19 VBN cord-310304-f28tjmi8 143 19 , , , cord-310304-f28tjmi8 143 20 they -PRON- PRP cord-310304-f28tjmi8 143 21 should should MD cord-310304-f28tjmi8 143 22 be be VB cord-310304-f28tjmi8 143 23 COVID-19-free COVID-19-free NNP cord-310304-f28tjmi8 143 24 ( ( -LRB- cord-310304-f28tjmi8 143 25 as as IN cord-310304-f28tjmi8 143 26 indicated indicate VBN cord-310304-f28tjmi8 143 27 by by IN cord-310304-f28tjmi8 143 28 polymerase polymerase NN cord-310304-f28tjmi8 143 29 chain chain NN cord-310304-f28tjmi8 143 30 reaction reaction NN cord-310304-f28tjmi8 143 31 ) ) -RRB- cord-310304-f28tjmi8 143 32 for for IN cord-310304-f28tjmi8 143 33 at at RB cord-310304-f28tjmi8 143 34 least least RBS cord-310304-f28tjmi8 143 35 14 14 CD cord-310304-f28tjmi8 143 36 days day NNS cord-310304-f28tjmi8 143 37 , , , cord-310304-f28tjmi8 143 38 owing owe VBG cord-310304-f28tjmi8 143 39 to to IN cord-310304-f28tjmi8 143 40 the the DT cord-310304-f28tjmi8 143 41 incubation incubation NN cord-310304-f28tjmi8 143 42 period period NN cord-310304-f28tjmi8 143 43 of of IN cord-310304-f28tjmi8 143 44 ~5 ~5 CD cord-310304-f28tjmi8 143 45 days day NNS cord-310304-f28tjmi8 143 46 and and CC cord-310304-f28tjmi8 143 47 onset onset NN cord-310304-f28tjmi8 143 48 of of IN cord-310304-f28tjmi8 143 49 symptoms symptom NNS cord-310304-f28tjmi8 143 50 in in IN cord-310304-f28tjmi8 143 51 ~11.5 ~11.5 CD cord-310304-f28tjmi8 143 52 days day NNS cord-310304-f28tjmi8 143 53 [ [ -LRB- cord-310304-f28tjmi8 143 54 70 70 CD cord-310304-f28tjmi8 143 55 ] ] -RRB- cord-310304-f28tjmi8 143 56 . . . cord-310304-f28tjmi8 144 1 The the DT cord-310304-f28tjmi8 144 2 2013 2013 CD cord-310304-f28tjmi8 144 3 American American NNP cord-310304-f28tjmi8 144 4 Thoracic Thoracic NNP cord-310304-f28tjmi8 144 5 Society Society NNP cord-310304-f28tjmi8 144 6 / / SYM cord-310304-f28tjmi8 144 7 European European NNP cord-310304-f28tjmi8 144 8 Respiratory Respiratory NNP cord-310304-f28tjmi8 144 9 Society Society NNP cord-310304-f28tjmi8 144 10 Committee Committee NNP cord-310304-f28tjmi8 144 11 , , , cord-310304-f28tjmi8 144 12 and and CC cord-310304-f28tjmi8 144 13 similarly similarly RB cord-310304-f28tjmi8 144 14 Healthy healthy JJ cord-310304-f28tjmi8 144 15 People People NNS cord-310304-f28tjmi8 144 16 2020 2020 CD cord-310304-f28tjmi8 144 17 , , , cord-310304-f28tjmi8 144 18 published publish VBD cord-310304-f28tjmi8 144 19 a a DT cord-310304-f28tjmi8 144 20 policy policy NN cord-310304-f28tjmi8 144 21 statement statement NN cord-310304-f28tjmi8 144 22 defining define VBG cord-310304-f28tjmi8 144 23 disparities disparity NNS cord-310304-f28tjmi8 144 24 in in IN cord-310304-f28tjmi8 144 25 respiratory respiratory JJ cord-310304-f28tjmi8 144 26 health health NN cord-310304-f28tjmi8 144 27 as as IN cord-310304-f28tjmi8 144 28 closely closely RB cord-310304-f28tjmi8 144 29 linked link VBN cord-310304-f28tjmi8 144 30 to to IN cord-310304-f28tjmi8 144 31 racial racial JJ cord-310304-f28tjmi8 144 32 ancestry ancestry NN cord-310304-f28tjmi8 144 33 , , , cord-310304-f28tjmi8 144 34 social social JJ cord-310304-f28tjmi8 144 35 , , , cord-310304-f28tjmi8 144 36 economic economic JJ cord-310304-f28tjmi8 144 37 , , , cord-310304-f28tjmi8 144 38 and/or and/or CC cord-310304-f28tjmi8 144 39 environmental environmental JJ cord-310304-f28tjmi8 144 40 differences difference NNS cord-310304-f28tjmi8 144 41 [ [ -LRB- cord-310304-f28tjmi8 144 42 71 71 CD cord-310304-f28tjmi8 144 43 ] ] -RRB- cord-310304-f28tjmi8 144 44 . . . cord-310304-f28tjmi8 145 1 Health health NN cord-310304-f28tjmi8 145 2 disparities disparity NNS cord-310304-f28tjmi8 145 3 in in IN cord-310304-f28tjmi8 145 4 respiratory respiratory JJ cord-310304-f28tjmi8 145 5 diseases disease NNS cord-310304-f28tjmi8 145 6 are be VBP cord-310304-f28tjmi8 145 7 14 14 CD cord-310304-f28tjmi8 145 8 times time NNS cord-310304-f28tjmi8 145 9 higher high JJR cord-310304-f28tjmi8 145 10 in in IN cord-310304-f28tjmi8 145 11 minority minority NN cord-310304-f28tjmi8 145 12 populations population NNS cord-310304-f28tjmi8 145 13 with with IN cord-310304-f28tjmi8 145 14 the the DT cord-310304-f28tjmi8 145 15 lowest low JJS cord-310304-f28tjmi8 145 16 socioeconomic socioeconomic JJ cord-310304-f28tjmi8 145 17 status status NN cord-310304-f28tjmi8 145 18 when when WRB cord-310304-f28tjmi8 145 19 compared compare VBN cord-310304-f28tjmi8 145 20 with with IN cord-310304-f28tjmi8 145 21 populations population NNS cord-310304-f28tjmi8 145 22 with with IN cord-310304-f28tjmi8 145 23 the the DT cord-310304-f28tjmi8 145 24 highest high JJS cord-310304-f28tjmi8 145 25 socioeconomic socioeconomic JJ cord-310304-f28tjmi8 145 26 status status NN cord-310304-f28tjmi8 145 27 [ [ -LRB- cord-310304-f28tjmi8 145 28 71 71 CD cord-310304-f28tjmi8 145 29 ] ] -RRB- cord-310304-f28tjmi8 145 30 . . . cord-310304-f28tjmi8 146 1 Globally globally RB cord-310304-f28tjmi8 146 2 , , , cord-310304-f28tjmi8 146 3 a a DT cord-310304-f28tjmi8 146 4 disproportionate disproportionate JJ cord-310304-f28tjmi8 146 5 burden burden NN cord-310304-f28tjmi8 146 6 of of IN cord-310304-f28tjmi8 146 7 Chronic chronic JJ cord-310304-f28tjmi8 146 8 obstructive obstructive JJ cord-310304-f28tjmi8 146 9 pulmonary pulmonary JJ cord-310304-f28tjmi8 146 10 disease disease NN cord-310304-f28tjmi8 146 11 ( ( -LRB- cord-310304-f28tjmi8 146 12 COPD COPD NNP cord-310304-f28tjmi8 146 13 ) ) -RRB- cord-310304-f28tjmi8 146 14 is be VBZ cord-310304-f28tjmi8 146 15 present present JJ cord-310304-f28tjmi8 146 16 among among IN cord-310304-f28tjmi8 146 17 minority minority NN cord-310304-f28tjmi8 146 18 communities community NNS cord-310304-f28tjmi8 146 19 due due JJ cord-310304-f28tjmi8 146 20 to to IN cord-310304-f28tjmi8 146 21 low low JJ cord-310304-f28tjmi8 146 22 socioeconomic socioeconomic JJ cord-310304-f28tjmi8 146 23 status status NN cord-310304-f28tjmi8 146 24 , , , cord-310304-f28tjmi8 146 25 differences difference NNS cord-310304-f28tjmi8 146 26 in in IN cord-310304-f28tjmi8 146 27 health health NN cord-310304-f28tjmi8 146 28 behaviors behavior NNS cord-310304-f28tjmi8 146 29 , , , cord-310304-f28tjmi8 146 30 occupational occupational JJ cord-310304-f28tjmi8 146 31 and and CC cord-310304-f28tjmi8 146 32 social social JJ cord-310304-f28tjmi8 146 33 environmental environmental JJ cord-310304-f28tjmi8 146 34 exposures exposure NNS cord-310304-f28tjmi8 146 35 , , , cord-310304-f28tjmi8 146 36 prenatal prenatal JJ cord-310304-f28tjmi8 146 37 and and CC cord-310304-f28tjmi8 146 38 childhood childhood NN cord-310304-f28tjmi8 146 39 exposures exposure NNS cord-310304-f28tjmi8 146 40 , , , cord-310304-f28tjmi8 146 41 respiratory respiratory JJ cord-310304-f28tjmi8 146 42 tract tract NN cord-310304-f28tjmi8 146 43 infections infection NNS cord-310304-f28tjmi8 146 44 , , , cord-310304-f28tjmi8 146 45 Hypothetical hypothetical JJ cord-310304-f28tjmi8 146 46 model model NN cord-310304-f28tjmi8 146 47 of of IN cord-310304-f28tjmi8 146 48 patients patient NNS cord-310304-f28tjmi8 146 49 with with IN cord-310304-f28tjmi8 146 50 CVD CVD NNP cord-310304-f28tjmi8 146 51 and and CC cord-310304-f28tjmi8 146 52 increased increase VBN cord-310304-f28tjmi8 146 53 risk risk NN cord-310304-f28tjmi8 146 54 for for IN cord-310304-f28tjmi8 146 55 complications complication NNS cord-310304-f28tjmi8 146 56 due due JJ cord-310304-f28tjmi8 146 57 to to IN cord-310304-f28tjmi8 146 58 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 146 59 . . . cord-310304-f28tjmi8 147 1 CVD CVD NNP cord-310304-f28tjmi8 147 2 patients patient NNS cord-310304-f28tjmi8 147 3 with with IN cord-310304-f28tjmi8 147 4 advanced advanced JJ cord-310304-f28tjmi8 147 5 age age NN cord-310304-f28tjmi8 147 6 and and CC cord-310304-f28tjmi8 147 7 elevated elevated JJ cord-310304-f28tjmi8 147 8 troponin troponin NN cord-310304-f28tjmi8 147 9 I -PRON- PRP cord-310304-f28tjmi8 147 10 levels level NNS cord-310304-f28tjmi8 147 11 , , , cord-310304-f28tjmi8 147 12 and and CC cord-310304-f28tjmi8 147 13 who who WP cord-310304-f28tjmi8 147 14 have have VBP cord-310304-f28tjmi8 147 15 abnormal abnormal JJ cord-310304-f28tjmi8 147 16 echocardiograms echocardiogram NNS cord-310304-f28tjmi8 147 17 , , , cord-310304-f28tjmi8 147 18 are be VBP cord-310304-f28tjmi8 147 19 at at IN cord-310304-f28tjmi8 147 20 high high JJ cord-310304-f28tjmi8 147 21 risk risk NN cord-310304-f28tjmi8 147 22 for for IN cord-310304-f28tjmi8 147 23 developing develop VBG cord-310304-f28tjmi8 147 24 more more RBR cord-310304-f28tjmi8 147 25 severe severe JJ cord-310304-f28tjmi8 147 26 COVID-19 covid-19 JJ cord-310304-f28tjmi8 147 27 disease disease NN cord-310304-f28tjmi8 147 28 . . . cord-310304-f28tjmi8 148 1 These these DT cord-310304-f28tjmi8 148 2 patients patient NNS cord-310304-f28tjmi8 148 3 have have VBP cord-310304-f28tjmi8 148 4 been be VBN cord-310304-f28tjmi8 148 5 shown show VBN cord-310304-f28tjmi8 148 6 to to TO cord-310304-f28tjmi8 148 7 have have VB cord-310304-f28tjmi8 148 8 increased increase VBN cord-310304-f28tjmi8 148 9 blood blood NN cord-310304-f28tjmi8 148 10 levels level NNS cord-310304-f28tjmi8 148 11 of of IN cord-310304-f28tjmi8 148 12 IL-6 IL-6 NNP cord-310304-f28tjmi8 148 13 , , , cord-310304-f28tjmi8 148 14 ferritin ferritin NN cord-310304-f28tjmi8 148 15 , , , cord-310304-f28tjmi8 148 16 LDH LDH NNP cord-310304-f28tjmi8 148 17 , , , cord-310304-f28tjmi8 148 18 and and CC cord-310304-f28tjmi8 148 19 D d NN cord-310304-f28tjmi8 148 20 - - HYPH cord-310304-f28tjmi8 148 21 dimer dimer NN cord-310304-f28tjmi8 148 22 , , , cord-310304-f28tjmi8 148 23 which which WDT cord-310304-f28tjmi8 148 24 are be VBP cord-310304-f28tjmi8 148 25 associated associate VBN cord-310304-f28tjmi8 148 26 with with IN cord-310304-f28tjmi8 148 27 the the DT cord-310304-f28tjmi8 148 28 cytokine cytokine NN cord-310304-f28tjmi8 148 29 storm storm NN cord-310304-f28tjmi8 148 30 that that WDT cord-310304-f28tjmi8 148 31 likely likely RB cord-310304-f28tjmi8 148 32 would would MD cord-310304-f28tjmi8 148 33 contribute contribute VB cord-310304-f28tjmi8 148 34 to to IN cord-310304-f28tjmi8 148 35 cardiac cardiac JJ cord-310304-f28tjmi8 148 36 injury injury NN cord-310304-f28tjmi8 148 37 . . . cord-310304-f28tjmi8 149 1 High high JJ cord-310304-f28tjmi8 149 2 levels level NNS cord-310304-f28tjmi8 149 3 of of IN cord-310304-f28tjmi8 149 4 ACE2 ACE2 NNP cord-310304-f28tjmi8 149 5 are be VBP cord-310304-f28tjmi8 149 6 known know VBN cord-310304-f28tjmi8 149 7 to to TO cord-310304-f28tjmi8 149 8 be be VB cord-310304-f28tjmi8 149 9 expressed express VBN cord-310304-f28tjmi8 149 10 on on IN cord-310304-f28tjmi8 149 11 cardiomyocytes cardiomyocyte NNS cord-310304-f28tjmi8 149 12 that that WDT cord-310304-f28tjmi8 149 13 could could MD cord-310304-f28tjmi8 149 14 result result VB cord-310304-f28tjmi8 149 15 in in IN cord-310304-f28tjmi8 149 16 direct direct JJ cord-310304-f28tjmi8 149 17 infection infection NN cord-310304-f28tjmi8 149 18 of of IN cord-310304-f28tjmi8 149 19 heart heart NN cord-310304-f28tjmi8 149 20 tissue tissue NN cord-310304-f28tjmi8 149 21 by by IN cord-310304-f28tjmi8 149 22 SARS SARS NNP cord-310304-f28tjmi8 149 23 - - HYPH cord-310304-f28tjmi8 149 24 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 149 25 , , , cord-310304-f28tjmi8 149 26 which which WDT cord-310304-f28tjmi8 149 27 is be VBZ cord-310304-f28tjmi8 149 28 thought think VBN cord-310304-f28tjmi8 149 29 to to TO cord-310304-f28tjmi8 149 30 induce induce VB cord-310304-f28tjmi8 149 31 hypoxia hypoxia NN cord-310304-f28tjmi8 149 32 leading lead VBG cord-310304-f28tjmi8 149 33 to to TO cord-310304-f28tjmi8 149 34 increase increase VB cord-310304-f28tjmi8 149 35 calcium calcium NN cord-310304-f28tjmi8 149 36 levels level NNS cord-310304-f28tjmi8 149 37 resulting result VBG cord-310304-f28tjmi8 149 38 in in IN cord-310304-f28tjmi8 149 39 apoptosis apoptosis NN cord-310304-f28tjmi8 149 40 and and CC cord-310304-f28tjmi8 149 41 death death NN cord-310304-f28tjmi8 149 42 of of IN cord-310304-f28tjmi8 149 43 cardiomyocytes cardiomyocyte NNS cord-310304-f28tjmi8 149 44 ; ; : cord-310304-f28tjmi8 149 45 this this DT cord-310304-f28tjmi8 149 46 likely likely RB cord-310304-f28tjmi8 149 47 would would MD cord-310304-f28tjmi8 149 48 contribute contribute VB cord-310304-f28tjmi8 149 49 to to IN cord-310304-f28tjmi8 149 50 myocardial myocardial JJ cord-310304-f28tjmi8 149 51 injury injury NN cord-310304-f28tjmi8 149 52 . . . cord-310304-f28tjmi8 150 1 The the DT cord-310304-f28tjmi8 150 2 2013 2013 CD cord-310304-f28tjmi8 150 3 American American NNP cord-310304-f28tjmi8 150 4 Thoracic Thoracic NNP cord-310304-f28tjmi8 150 5 Society Society NNP cord-310304-f28tjmi8 150 6 / / SYM cord-310304-f28tjmi8 150 7 European European NNP cord-310304-f28tjmi8 150 8 Respiratory Respiratory NNP cord-310304-f28tjmi8 150 9 Society Society NNP cord-310304-f28tjmi8 150 10 Committee Committee NNP cord-310304-f28tjmi8 150 11 , , , cord-310304-f28tjmi8 150 12 and and CC cord-310304-f28tjmi8 150 13 similarly similarly RB cord-310304-f28tjmi8 150 14 Healthy healthy JJ cord-310304-f28tjmi8 150 15 People People NNS cord-310304-f28tjmi8 150 16 2020 2020 CD cord-310304-f28tjmi8 150 17 , , , cord-310304-f28tjmi8 150 18 published publish VBD cord-310304-f28tjmi8 150 19 a a DT cord-310304-f28tjmi8 150 20 policy policy NN cord-310304-f28tjmi8 150 21 statement statement NN cord-310304-f28tjmi8 150 22 defining define VBG cord-310304-f28tjmi8 150 23 disparities disparity NNS cord-310304-f28tjmi8 150 24 in in IN cord-310304-f28tjmi8 150 25 respiratory respiratory JJ cord-310304-f28tjmi8 150 26 health health NN cord-310304-f28tjmi8 150 27 as as IN cord-310304-f28tjmi8 150 28 closely closely RB cord-310304-f28tjmi8 150 29 linked link VBN cord-310304-f28tjmi8 150 30 to to IN cord-310304-f28tjmi8 150 31 racial racial JJ cord-310304-f28tjmi8 150 32 ancestry ancestry NN cord-310304-f28tjmi8 150 33 , , , cord-310304-f28tjmi8 150 34 social social JJ cord-310304-f28tjmi8 150 35 , , , cord-310304-f28tjmi8 150 36 economic economic JJ cord-310304-f28tjmi8 150 37 , , , cord-310304-f28tjmi8 150 38 and/or and/or CC cord-310304-f28tjmi8 150 39 environmental environmental JJ cord-310304-f28tjmi8 150 40 differences difference NNS cord-310304-f28tjmi8 150 41 [ [ -LRB- cord-310304-f28tjmi8 150 42 71 71 CD cord-310304-f28tjmi8 150 43 ] ] -RRB- cord-310304-f28tjmi8 150 44 . . . cord-310304-f28tjmi8 151 1 Health health NN cord-310304-f28tjmi8 151 2 disparities disparity NNS cord-310304-f28tjmi8 151 3 in in IN cord-310304-f28tjmi8 151 4 respiratory respiratory JJ cord-310304-f28tjmi8 151 5 diseases disease NNS cord-310304-f28tjmi8 151 6 are be VBP cord-310304-f28tjmi8 151 7 14 14 CD cord-310304-f28tjmi8 151 8 times time NNS cord-310304-f28tjmi8 151 9 higher high JJR cord-310304-f28tjmi8 151 10 in in IN cord-310304-f28tjmi8 151 11 minority minority NN cord-310304-f28tjmi8 151 12 populations population NNS cord-310304-f28tjmi8 151 13 with with IN cord-310304-f28tjmi8 151 14 the the DT cord-310304-f28tjmi8 151 15 lowest low JJS cord-310304-f28tjmi8 151 16 socioeconomic socioeconomic JJ cord-310304-f28tjmi8 151 17 status status NN cord-310304-f28tjmi8 151 18 when when WRB cord-310304-f28tjmi8 151 19 compared compare VBN cord-310304-f28tjmi8 151 20 with with IN cord-310304-f28tjmi8 151 21 populations population NNS cord-310304-f28tjmi8 151 22 with with IN cord-310304-f28tjmi8 151 23 the the DT cord-310304-f28tjmi8 151 24 highest high JJS cord-310304-f28tjmi8 151 25 socioeconomic socioeconomic JJ cord-310304-f28tjmi8 151 26 status status NN cord-310304-f28tjmi8 151 27 [ [ -LRB- cord-310304-f28tjmi8 151 28 71 71 CD cord-310304-f28tjmi8 151 29 ] ] -RRB- cord-310304-f28tjmi8 151 30 . . . cord-310304-f28tjmi8 152 1 Globally globally RB cord-310304-f28tjmi8 152 2 , , , cord-310304-f28tjmi8 152 3 a a DT cord-310304-f28tjmi8 152 4 disproportionate disproportionate JJ cord-310304-f28tjmi8 152 5 burden burden NN cord-310304-f28tjmi8 152 6 of of IN cord-310304-f28tjmi8 152 7 Chronic chronic JJ cord-310304-f28tjmi8 152 8 obstructive obstructive JJ cord-310304-f28tjmi8 152 9 pulmonary pulmonary JJ cord-310304-f28tjmi8 152 10 disease disease NN cord-310304-f28tjmi8 152 11 ( ( -LRB- cord-310304-f28tjmi8 152 12 COPD COPD NNP cord-310304-f28tjmi8 152 13 ) ) -RRB- cord-310304-f28tjmi8 152 14 is be VBZ cord-310304-f28tjmi8 152 15 present present JJ cord-310304-f28tjmi8 152 16 among among IN cord-310304-f28tjmi8 152 17 minority minority NN cord-310304-f28tjmi8 152 18 communities community NNS cord-310304-f28tjmi8 152 19 due due JJ cord-310304-f28tjmi8 152 20 to to IN cord-310304-f28tjmi8 152 21 low low JJ cord-310304-f28tjmi8 152 22 socioeconomic socioeconomic JJ cord-310304-f28tjmi8 152 23 status status NN cord-310304-f28tjmi8 152 24 , , , cord-310304-f28tjmi8 152 25 differences difference NNS cord-310304-f28tjmi8 152 26 in in IN cord-310304-f28tjmi8 152 27 health health NN cord-310304-f28tjmi8 152 28 behaviors behavior NNS cord-310304-f28tjmi8 152 29 , , , cord-310304-f28tjmi8 152 30 occupational occupational JJ cord-310304-f28tjmi8 152 31 and and CC cord-310304-f28tjmi8 152 32 social social JJ cord-310304-f28tjmi8 152 33 environmental environmental JJ cord-310304-f28tjmi8 152 34 exposures exposure NNS cord-310304-f28tjmi8 152 35 , , , cord-310304-f28tjmi8 152 36 prenatal prenatal JJ cord-310304-f28tjmi8 152 37 and and CC cord-310304-f28tjmi8 152 38 childhood childhood NN cord-310304-f28tjmi8 152 39 exposures exposure NNS cord-310304-f28tjmi8 152 40 , , , cord-310304-f28tjmi8 152 41 respiratory respiratory JJ cord-310304-f28tjmi8 152 42 tract tract NN cord-310304-f28tjmi8 152 43 infections infection NNS cord-310304-f28tjmi8 152 44 , , , cord-310304-f28tjmi8 152 45 and and CC cord-310304-f28tjmi8 152 46 tobacco tobacco NN cord-310304-f28tjmi8 152 47 use use NN cord-310304-f28tjmi8 152 48 . . . cord-310304-f28tjmi8 153 1 These these DT cord-310304-f28tjmi8 153 2 factors factor NNS cord-310304-f28tjmi8 153 3 are be VBP cord-310304-f28tjmi8 153 4 associated associate VBN cord-310304-f28tjmi8 153 5 with with IN cord-310304-f28tjmi8 153 6 the the DT cord-310304-f28tjmi8 153 7 risk risk NN cord-310304-f28tjmi8 153 8 of of IN cord-310304-f28tjmi8 153 9 developing develop VBG cord-310304-f28tjmi8 153 10 COPD COPD NNP cord-310304-f28tjmi8 153 11 and and CC cord-310304-f28tjmi8 153 12 are be VBP cord-310304-f28tjmi8 153 13 associated associate VBN cord-310304-f28tjmi8 153 14 with with IN cord-310304-f28tjmi8 153 15 poor poor JJ cord-310304-f28tjmi8 153 16 clinical clinical JJ cord-310304-f28tjmi8 153 17 outcomes outcome NNS cord-310304-f28tjmi8 153 18 related relate VBN cord-310304-f28tjmi8 153 19 to to IN cord-310304-f28tjmi8 153 20 COPD COPD NNP cord-310304-f28tjmi8 153 21 clinical clinical JJ cord-310304-f28tjmi8 153 22 presentations presentation NNS cord-310304-f28tjmi8 153 23 [ [ -LRB- cord-310304-f28tjmi8 153 24 72 72 CD cord-310304-f28tjmi8 153 25 ] ] -RRB- cord-310304-f28tjmi8 153 26 . . . cord-310304-f28tjmi8 154 1 According accord VBG cord-310304-f28tjmi8 154 2 to to IN cord-310304-f28tjmi8 154 3 the the DT cord-310304-f28tjmi8 154 4 WHO WHO NNP cord-310304-f28tjmi8 154 5 , , , cord-310304-f28tjmi8 154 6 > > XX cord-310304-f28tjmi8 154 7 90 90 CD cord-310304-f28tjmi8 154 8 % % NN cord-310304-f28tjmi8 154 9 of of IN cord-310304-f28tjmi8 154 10 COPD COPD NNP cord-310304-f28tjmi8 154 11 deaths death NNS cord-310304-f28tjmi8 154 12 occur occur VBP cord-310304-f28tjmi8 154 13 in in IN cord-310304-f28tjmi8 154 14 low low JJ cord-310304-f28tjmi8 154 15 - - HYPH cord-310304-f28tjmi8 154 16 income income NN cord-310304-f28tjmi8 154 17 and and CC cord-310304-f28tjmi8 154 18 middle middle JJ cord-310304-f28tjmi8 154 19 - - HYPH cord-310304-f28tjmi8 154 20 income income NN cord-310304-f28tjmi8 154 21 countries country NNS cord-310304-f28tjmi8 154 22 [ [ -LRB- cord-310304-f28tjmi8 154 23 73 73 CD cord-310304-f28tjmi8 154 24 ] ] -RRB- cord-310304-f28tjmi8 154 25 . . . cord-310304-f28tjmi8 155 1 Social social JJ cord-310304-f28tjmi8 155 2 determinants determinant NNS cord-310304-f28tjmi8 155 3 of of IN cord-310304-f28tjmi8 155 4 health health NN cord-310304-f28tjmi8 155 5 , , , cord-310304-f28tjmi8 155 6 including include VBG cord-310304-f28tjmi8 155 7 economic economic JJ cord-310304-f28tjmi8 155 8 stability stability NN cord-310304-f28tjmi8 155 9 , , , cord-310304-f28tjmi8 155 10 education education NN cord-310304-f28tjmi8 155 11 , , , cord-310304-f28tjmi8 155 12 access access NN cord-310304-f28tjmi8 155 13 to to IN cord-310304-f28tjmi8 155 14 health health NN cord-310304-f28tjmi8 155 15 care care NN cord-310304-f28tjmi8 155 16 , , , cord-310304-f28tjmi8 155 17 and and CC cord-310304-f28tjmi8 155 18 environment environment NN cord-310304-f28tjmi8 155 19 , , , cord-310304-f28tjmi8 155 20 play play VB cord-310304-f28tjmi8 155 21 a a DT cord-310304-f28tjmi8 155 22 critical critical JJ cord-310304-f28tjmi8 155 23 role role NN cord-310304-f28tjmi8 155 24 in in IN cord-310304-f28tjmi8 155 25 establishing establish VBG cord-310304-f28tjmi8 155 26 health health NN cord-310304-f28tjmi8 155 27 equity equity NN cord-310304-f28tjmi8 155 28 that that WDT cord-310304-f28tjmi8 155 29 will will MD cord-310304-f28tjmi8 155 30 reduce reduce VB cord-310304-f28tjmi8 155 31 disparity disparity NN cord-310304-f28tjmi8 155 32 - - HYPH cord-310304-f28tjmi8 155 33 related relate VBN cord-310304-f28tjmi8 155 34 respiratory respiratory JJ cord-310304-f28tjmi8 155 35 diseases disease NNS cord-310304-f28tjmi8 155 36 , , , cord-310304-f28tjmi8 155 37 such such JJ cord-310304-f28tjmi8 155 38 as as IN cord-310304-f28tjmi8 155 39 COPD COPD NNP cord-310304-f28tjmi8 155 40 , , , cord-310304-f28tjmi8 155 41 during during IN cord-310304-f28tjmi8 155 42 a a DT cord-310304-f28tjmi8 155 43 lifespan lifespan NN cord-310304-f28tjmi8 155 44 [ [ -LRB- cord-310304-f28tjmi8 155 45 74 74 CD cord-310304-f28tjmi8 155 46 , , , cord-310304-f28tjmi8 155 47 75 75 CD cord-310304-f28tjmi8 155 48 ] ] -RRB- cord-310304-f28tjmi8 155 49 . . . cord-310304-f28tjmi8 156 1 COPD COPD NNP cord-310304-f28tjmi8 156 2 is be VBZ cord-310304-f28tjmi8 156 3 a a DT cord-310304-f28tjmi8 156 4 condition condition NN cord-310304-f28tjmi8 156 5 that that WDT cord-310304-f28tjmi8 156 6 predisposes predispose VBZ cord-310304-f28tjmi8 156 7 COVID-19 covid-19 CD cord-310304-f28tjmi8 156 8 patients patient NNS cord-310304-f28tjmi8 156 9 to to IN cord-310304-f28tjmi8 156 10 worse bad JJR cord-310304-f28tjmi8 156 11 clinical clinical JJ cord-310304-f28tjmi8 156 12 outcomes outcome NNS cord-310304-f28tjmi8 156 13 [ [ -LRB- cord-310304-f28tjmi8 156 14 76 76 CD cord-310304-f28tjmi8 156 15 ] ] -RRB- cord-310304-f28tjmi8 156 16 . . . cord-310304-f28tjmi8 157 1 Smokers smoker NNS cord-310304-f28tjmi8 157 2 and and CC cord-310304-f28tjmi8 157 3 individuals individual NNS cord-310304-f28tjmi8 157 4 with with IN cord-310304-f28tjmi8 157 5 COPD COPD NNP cord-310304-f28tjmi8 157 6 have have VBP cord-310304-f28tjmi8 157 7 increased increase VBN cord-310304-f28tjmi8 157 8 airway airway NN cord-310304-f28tjmi8 157 9 expression expression NN cord-310304-f28tjmi8 157 10 of of IN cord-310304-f28tjmi8 157 11 the the DT cord-310304-f28tjmi8 157 12 ACE2 ACE2 NNP cord-310304-f28tjmi8 157 13 receptor receptor NN cord-310304-f28tjmi8 157 14 for for IN cord-310304-f28tjmi8 157 15 SAR SAR NNP cord-310304-f28tjmi8 157 16 - - HYPH cord-310304-f28tjmi8 157 17 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 157 18 [ [ -LRB- cord-310304-f28tjmi8 157 19 77 77 CD cord-310304-f28tjmi8 157 20 ] ] -RRB- cord-310304-f28tjmi8 157 21 . . . cord-310304-f28tjmi8 158 1 COVID-19 covid-19 JJ cord-310304-f28tjmi8 158 2 patients patient NNS cord-310304-f28tjmi8 158 3 with with IN cord-310304-f28tjmi8 158 4 COPD COPD NNP cord-310304-f28tjmi8 158 5 who who WP cord-310304-f28tjmi8 158 6 are be VBP cord-310304-f28tjmi8 158 7 current current JJ cord-310304-f28tjmi8 158 8 smokers smoker NNS cord-310304-f28tjmi8 158 9 and and CC cord-310304-f28tjmi8 158 10 have have VBP cord-310304-f28tjmi8 158 11 other other JJ cord-310304-f28tjmi8 158 12 types type NNS cord-310304-f28tjmi8 158 13 of of IN cord-310304-f28tjmi8 158 14 lung lung NN cord-310304-f28tjmi8 158 15 disease disease NN cord-310304-f28tjmi8 158 16 , , , cord-310304-f28tjmi8 158 17 including include VBG cord-310304-f28tjmi8 158 18 asthma asthma NN cord-310304-f28tjmi8 158 19 , , , cord-310304-f28tjmi8 158 20 have have VBP cord-310304-f28tjmi8 158 21 poor poor JJ cord-310304-f28tjmi8 158 22 clinical clinical JJ cord-310304-f28tjmi8 158 23 outcomes outcome NNS cord-310304-f28tjmi8 158 24 ( ( -LRB- cord-310304-f28tjmi8 158 25 Figure figure NN cord-310304-f28tjmi8 158 26 4 4 CD cord-310304-f28tjmi8 158 27 ) ) -RRB- cord-310304-f28tjmi8 158 28 . . . cord-310304-f28tjmi8 159 1 SARS SARS NNP cord-310304-f28tjmi8 159 2 - - HYPH cord-310304-f28tjmi8 159 3 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 159 4 infection infection NN cord-310304-f28tjmi8 159 5 via via IN cord-310304-f28tjmi8 159 6 ACE2 ACE2 NNP cord-310304-f28tjmi8 159 7 entry entry NN cord-310304-f28tjmi8 159 8 into into IN cord-310304-f28tjmi8 159 9 the the DT cord-310304-f28tjmi8 159 10 alveolar alveolar JJ cord-310304-f28tjmi8 159 11 epithelial epithelial JJ cord-310304-f28tjmi8 159 12 cells cell NNS cord-310304-f28tjmi8 159 13 of of IN cord-310304-f28tjmi8 159 14 COPD COPD NNP cord-310304-f28tjmi8 159 15 patients patient NNS cord-310304-f28tjmi8 159 16 who who WP cord-310304-f28tjmi8 159 17 smoke smoke VBP cord-310304-f28tjmi8 159 18 may may MD cord-310304-f28tjmi8 159 19 lead lead VB cord-310304-f28tjmi8 159 20 to to IN cord-310304-f28tjmi8 159 21 increased increase VBN cord-310304-f28tjmi8 159 22 surface surface NN cord-310304-f28tjmi8 159 23 - - HYPH cord-310304-f28tjmi8 159 24 expression expression NN cord-310304-f28tjmi8 159 25 ACE2 ACE2 NNP cord-310304-f28tjmi8 159 26 on on IN cord-310304-f28tjmi8 159 27 lung lung NN cord-310304-f28tjmi8 159 28 epithelium epithelium NN cord-310304-f28tjmi8 159 29 , , , cord-310304-f28tjmi8 159 30 which which WDT cord-310304-f28tjmi8 159 31 may may MD cord-310304-f28tjmi8 159 32 increase increase VB cord-310304-f28tjmi8 159 33 the the DT cord-310304-f28tjmi8 159 34 rate rate NN cord-310304-f28tjmi8 159 35 of of IN cord-310304-f28tjmi8 159 36 infection infection NN cord-310304-f28tjmi8 159 37 in in IN cord-310304-f28tjmi8 159 38 the the DT cord-310304-f28tjmi8 159 39 lung lung NN cord-310304-f28tjmi8 159 40 and and CC cord-310304-f28tjmi8 159 41 contribute contribute VB cord-310304-f28tjmi8 159 42 to to IN cord-310304-f28tjmi8 159 43 higher high JJR cord-310304-f28tjmi8 159 44 viral viral JJ cord-310304-f28tjmi8 159 45 loads load NNS cord-310304-f28tjmi8 159 46 ( ( -LRB- cord-310304-f28tjmi8 159 47 Figure figure NN cord-310304-f28tjmi8 159 48 4 4 CD cord-310304-f28tjmi8 159 49 ) ) -RRB- cord-310304-f28tjmi8 159 50 . . . cord-310304-f28tjmi8 160 1 Alveolar alveolar NN cord-310304-f28tjmi8 160 2 cells cell NNS cord-310304-f28tjmi8 160 3 pneumocytes pneumocyte NNS cord-310304-f28tjmi8 160 4 type type NN cord-310304-f28tjmi8 160 5 II II NNP cord-310304-f28tjmi8 160 6 are be VBP cord-310304-f28tjmi8 160 7 highly highly RB cord-310304-f28tjmi8 160 8 permissive permissive JJ cord-310304-f28tjmi8 160 9 for for IN cord-310304-f28tjmi8 160 10 SARS SARS NNP cord-310304-f28tjmi8 160 11 - - HYPH cord-310304-f28tjmi8 160 12 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 160 13 infection infection NN cord-310304-f28tjmi8 160 14 resulting result VBG cord-310304-f28tjmi8 160 15 in in IN cord-310304-f28tjmi8 160 16 alveolar alveolar JJ cord-310304-f28tjmi8 160 17 dysfunction dysfunction NN cord-310304-f28tjmi8 160 18 , , , cord-310304-f28tjmi8 160 19 inflammation inflammation NN cord-310304-f28tjmi8 160 20 , , , cord-310304-f28tjmi8 160 21 vascular vascular JJ cord-310304-f28tjmi8 160 22 leakage leakage NN cord-310304-f28tjmi8 160 23 , , , cord-310304-f28tjmi8 160 24 development development NN cord-310304-f28tjmi8 160 25 of of IN cord-310304-f28tjmi8 160 26 pulmonary pulmonary JJ cord-310304-f28tjmi8 160 27 emboli embolus NNS cord-310304-f28tjmi8 160 28 , , , cord-310304-f28tjmi8 160 29 and and CC cord-310304-f28tjmi8 160 30 acute acute JJ cord-310304-f28tjmi8 160 31 respiratory respiratory JJ cord-310304-f28tjmi8 160 32 distress distress NN cord-310304-f28tjmi8 160 33 from from IN cord-310304-f28tjmi8 160 34 poor poor JJ cord-310304-f28tjmi8 160 35 gas gas NN cord-310304-f28tjmi8 160 36 exchange exchange NN cord-310304-f28tjmi8 160 37 ( ( -LRB- cord-310304-f28tjmi8 160 38 Figure Figure NNP cord-310304-f28tjmi8 160 39 4 4 CD cord-310304-f28tjmi8 160 40 ) ) -RRB- cord-310304-f28tjmi8 160 41 . . . cord-310304-f28tjmi8 161 1 Progressive progressive JJ cord-310304-f28tjmi8 161 2 viral viral JJ cord-310304-f28tjmi8 161 3 infection infection NN cord-310304-f28tjmi8 161 4 and and CC cord-310304-f28tjmi8 161 5 the the DT cord-310304-f28tjmi8 161 6 pro pro JJ cord-310304-f28tjmi8 161 7 - - JJ cord-310304-f28tjmi8 161 8 inflammatory inflammatory JJ cord-310304-f28tjmi8 161 9 conditions condition NNS cord-310304-f28tjmi8 161 10 lead lead VBP cord-310304-f28tjmi8 161 11 to to IN cord-310304-f28tjmi8 161 12 pulmonary pulmonary JJ cord-310304-f28tjmi8 161 13 vascular vascular JJ cord-310304-f28tjmi8 161 14 leakage leakage NN cord-310304-f28tjmi8 161 15 , , , cord-310304-f28tjmi8 161 16 alveolar alveolar JJ cord-310304-f28tjmi8 161 17 edema edema NN cord-310304-f28tjmi8 161 18 , , , cord-310304-f28tjmi8 161 19 monocyte monocyte JJ cord-310304-f28tjmi8 161 20 infiltration infiltration NN cord-310304-f28tjmi8 161 21 , , , cord-310304-f28tjmi8 161 22 and and CC cord-310304-f28tjmi8 161 23 pneumonia pneumonia NN cord-310304-f28tjmi8 161 24 ( ( -LRB- cord-310304-f28tjmi8 161 25 Figure figure NN cord-310304-f28tjmi8 161 26 4 4 CD cord-310304-f28tjmi8 161 27 ) ) -RRB- cord-310304-f28tjmi8 161 28 . . . cord-310304-f28tjmi8 162 1 Patients patient NNS cord-310304-f28tjmi8 162 2 often often RB cord-310304-f28tjmi8 162 3 require require VBP cord-310304-f28tjmi8 162 4 mechanical mechanical JJ cord-310304-f28tjmi8 162 5 ventilation ventilation NN cord-310304-f28tjmi8 162 6 resulting result VBG cord-310304-f28tjmi8 162 7 in in IN cord-310304-f28tjmi8 162 8 delayed delay VBN cord-310304-f28tjmi8 162 9 recovery recovery NN cord-310304-f28tjmi8 162 10 , , , cord-310304-f28tjmi8 162 11 respiratory respiratory JJ cord-310304-f28tjmi8 162 12 failure failure NN cord-310304-f28tjmi8 162 13 , , , cord-310304-f28tjmi8 162 14 septic septic JJ cord-310304-f28tjmi8 162 15 shock shock NN cord-310304-f28tjmi8 162 16 , , , cord-310304-f28tjmi8 162 17 or or CC cord-310304-f28tjmi8 162 18 MOD mod NN cord-310304-f28tjmi8 162 19 or or CC cord-310304-f28tjmi8 162 20 failure failure NN cord-310304-f28tjmi8 162 21 ( ( -LRB- cord-310304-f28tjmi8 162 22 Figure figure NN cord-310304-f28tjmi8 162 23 4 4 CD cord-310304-f28tjmi8 162 24 ) ) -RRB- cord-310304-f28tjmi8 162 25 . . . cord-310304-f28tjmi8 163 1 Smokers smoker NNS cord-310304-f28tjmi8 163 2 and and CC cord-310304-f28tjmi8 163 3 individuals individual NNS cord-310304-f28tjmi8 163 4 with with IN cord-310304-f28tjmi8 163 5 COPD COPD NNP cord-310304-f28tjmi8 163 6 have have VBP cord-310304-f28tjmi8 163 7 increased increase VBN cord-310304-f28tjmi8 163 8 airway airway NN cord-310304-f28tjmi8 163 9 expression expression NN cord-310304-f28tjmi8 163 10 of of IN cord-310304-f28tjmi8 163 11 the the DT cord-310304-f28tjmi8 163 12 ACE2 ACE2 NNP cord-310304-f28tjmi8 163 13 receptor receptor NN cord-310304-f28tjmi8 163 14 for for IN cord-310304-f28tjmi8 163 15 SAR SAR NNP cord-310304-f28tjmi8 163 16 - - HYPH cord-310304-f28tjmi8 163 17 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 163 18 [ [ -LRB- cord-310304-f28tjmi8 163 19 77 77 CD cord-310304-f28tjmi8 163 20 ] ] -RRB- cord-310304-f28tjmi8 163 21 . . . cord-310304-f28tjmi8 164 1 COVID-19 covid-19 JJ cord-310304-f28tjmi8 164 2 patients patient NNS cord-310304-f28tjmi8 164 3 with with IN cord-310304-f28tjmi8 164 4 COPD COPD NNP cord-310304-f28tjmi8 164 5 who who WP cord-310304-f28tjmi8 164 6 are be VBP cord-310304-f28tjmi8 164 7 current current JJ cord-310304-f28tjmi8 164 8 smokers smoker NNS cord-310304-f28tjmi8 164 9 and and CC cord-310304-f28tjmi8 164 10 have have VBP cord-310304-f28tjmi8 164 11 other other JJ cord-310304-f28tjmi8 164 12 types type NNS cord-310304-f28tjmi8 164 13 of of IN cord-310304-f28tjmi8 164 14 lung lung NN cord-310304-f28tjmi8 164 15 disease disease NN cord-310304-f28tjmi8 164 16 , , , cord-310304-f28tjmi8 164 17 including include VBG cord-310304-f28tjmi8 164 18 asthma asthma NN cord-310304-f28tjmi8 164 19 , , , cord-310304-f28tjmi8 164 20 have have VBP cord-310304-f28tjmi8 164 21 poor poor JJ cord-310304-f28tjmi8 164 22 clinical clinical JJ cord-310304-f28tjmi8 164 23 outcomes outcome NNS cord-310304-f28tjmi8 164 24 ( ( -LRB- cord-310304-f28tjmi8 164 25 Figure figure NN cord-310304-f28tjmi8 164 26 4 4 CD cord-310304-f28tjmi8 164 27 ) ) -RRB- cord-310304-f28tjmi8 164 28 . . . cord-310304-f28tjmi8 165 1 SARS SARS NNP cord-310304-f28tjmi8 165 2 - - HYPH cord-310304-f28tjmi8 165 3 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 165 4 infection infection NN cord-310304-f28tjmi8 165 5 via via IN cord-310304-f28tjmi8 165 6 ACE2 ACE2 NNP cord-310304-f28tjmi8 165 7 entry entry NN cord-310304-f28tjmi8 165 8 into into IN cord-310304-f28tjmi8 165 9 the the DT cord-310304-f28tjmi8 165 10 alveolar alveolar JJ cord-310304-f28tjmi8 165 11 epithelial epithelial JJ cord-310304-f28tjmi8 165 12 cells cell NNS cord-310304-f28tjmi8 165 13 of of IN cord-310304-f28tjmi8 165 14 COPD COPD NNP cord-310304-f28tjmi8 165 15 patients patient NNS cord-310304-f28tjmi8 165 16 who who WP cord-310304-f28tjmi8 165 17 smoke smoke VBP cord-310304-f28tjmi8 165 18 may may MD cord-310304-f28tjmi8 165 19 lead lead VB cord-310304-f28tjmi8 165 20 to to IN cord-310304-f28tjmi8 165 21 increased increase VBN cord-310304-f28tjmi8 165 22 surface surface NN cord-310304-f28tjmi8 165 23 - - HYPH cord-310304-f28tjmi8 165 24 expression expression NN cord-310304-f28tjmi8 165 25 ACE2 ACE2 NNP cord-310304-f28tjmi8 165 26 on on IN cord-310304-f28tjmi8 165 27 lung lung NN cord-310304-f28tjmi8 165 28 epithelium epithelium NN cord-310304-f28tjmi8 165 29 , , , cord-310304-f28tjmi8 165 30 which which WDT cord-310304-f28tjmi8 165 31 may may MD cord-310304-f28tjmi8 165 32 increase increase VB cord-310304-f28tjmi8 165 33 the the DT cord-310304-f28tjmi8 165 34 rate rate NN cord-310304-f28tjmi8 165 35 of of IN cord-310304-f28tjmi8 165 36 infection infection NN cord-310304-f28tjmi8 165 37 in in IN cord-310304-f28tjmi8 165 38 the the DT cord-310304-f28tjmi8 165 39 lung lung NN cord-310304-f28tjmi8 165 40 and and CC cord-310304-f28tjmi8 165 41 contribute contribute VB cord-310304-f28tjmi8 165 42 to to IN cord-310304-f28tjmi8 165 43 higher high JJR cord-310304-f28tjmi8 165 44 viral viral JJ cord-310304-f28tjmi8 165 45 loads load NNS cord-310304-f28tjmi8 165 46 ( ( -LRB- cord-310304-f28tjmi8 165 47 Figure figure NN cord-310304-f28tjmi8 165 48 4 4 CD cord-310304-f28tjmi8 165 49 ) ) -RRB- cord-310304-f28tjmi8 165 50 . . . cord-310304-f28tjmi8 166 1 Alveolar alveolar NN cord-310304-f28tjmi8 166 2 cells cell NNS cord-310304-f28tjmi8 166 3 pneumocytes pneumocyte NNS cord-310304-f28tjmi8 166 4 type type NN cord-310304-f28tjmi8 166 5 II II NNP cord-310304-f28tjmi8 166 6 are be VBP cord-310304-f28tjmi8 166 7 highly highly RB cord-310304-f28tjmi8 166 8 permissive permissive JJ cord-310304-f28tjmi8 166 9 for for IN cord-310304-f28tjmi8 166 10 SARS SARS NNP cord-310304-f28tjmi8 166 11 - - HYPH cord-310304-f28tjmi8 166 12 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 166 13 infection infection NN cord-310304-f28tjmi8 166 14 resulting result VBG cord-310304-f28tjmi8 166 15 in in IN cord-310304-f28tjmi8 166 16 alveolar alveolar JJ cord-310304-f28tjmi8 166 17 dysfunction dysfunction NN cord-310304-f28tjmi8 166 18 , , , cord-310304-f28tjmi8 166 19 inflammation inflammation NN cord-310304-f28tjmi8 166 20 , , , cord-310304-f28tjmi8 166 21 vascular vascular JJ cord-310304-f28tjmi8 166 22 leakage leakage NN cord-310304-f28tjmi8 166 23 , , , cord-310304-f28tjmi8 166 24 development development NN cord-310304-f28tjmi8 166 25 of of IN cord-310304-f28tjmi8 166 26 pulmonary pulmonary JJ cord-310304-f28tjmi8 166 27 emboli embolus NNS cord-310304-f28tjmi8 166 28 , , , cord-310304-f28tjmi8 166 29 and and CC cord-310304-f28tjmi8 166 30 acute acute JJ cord-310304-f28tjmi8 166 31 respiratory respiratory JJ cord-310304-f28tjmi8 166 32 distress distress NN cord-310304-f28tjmi8 166 33 from from IN cord-310304-f28tjmi8 166 34 poor poor JJ cord-310304-f28tjmi8 166 35 gas gas NN cord-310304-f28tjmi8 166 36 exchange exchange NN cord-310304-f28tjmi8 166 37 ( ( -LRB- cord-310304-f28tjmi8 166 38 Figure Figure NNP cord-310304-f28tjmi8 166 39 4 4 CD cord-310304-f28tjmi8 166 40 ) ) -RRB- cord-310304-f28tjmi8 166 41 . . . cord-310304-f28tjmi8 167 1 Progressive progressive JJ cord-310304-f28tjmi8 167 2 viral viral JJ cord-310304-f28tjmi8 167 3 infection infection NN cord-310304-f28tjmi8 167 4 and and CC cord-310304-f28tjmi8 167 5 the the DT cord-310304-f28tjmi8 167 6 pro pro JJ cord-310304-f28tjmi8 167 7 - - JJ cord-310304-f28tjmi8 167 8 inflammatory inflammatory JJ cord-310304-f28tjmi8 167 9 conditions condition NNS cord-310304-f28tjmi8 167 10 lead lead VBP cord-310304-f28tjmi8 167 11 to to IN cord-310304-f28tjmi8 167 12 pulmonary pulmonary JJ cord-310304-f28tjmi8 167 13 vascular vascular JJ cord-310304-f28tjmi8 167 14 leakage leakage NN cord-310304-f28tjmi8 167 15 , , , cord-310304-f28tjmi8 167 16 alveolar alveolar JJ cord-310304-f28tjmi8 167 17 edema edema NN cord-310304-f28tjmi8 167 18 , , , cord-310304-f28tjmi8 167 19 monocyte monocyte JJ cord-310304-f28tjmi8 167 20 infiltration infiltration NN cord-310304-f28tjmi8 167 21 , , , cord-310304-f28tjmi8 167 22 and and CC cord-310304-f28tjmi8 167 23 pneumonia pneumonia NN cord-310304-f28tjmi8 167 24 ( ( -LRB- cord-310304-f28tjmi8 167 25 Figure figure NN cord-310304-f28tjmi8 167 26 4 4 CD cord-310304-f28tjmi8 167 27 ) ) -RRB- cord-310304-f28tjmi8 167 28 . . . cord-310304-f28tjmi8 168 1 Patients patient NNS cord-310304-f28tjmi8 168 2 often often RB cord-310304-f28tjmi8 168 3 require require VBP cord-310304-f28tjmi8 168 4 mechanical mechanical JJ cord-310304-f28tjmi8 168 5 ventilation ventilation NN cord-310304-f28tjmi8 168 6 resulting result VBG cord-310304-f28tjmi8 168 7 in in IN cord-310304-f28tjmi8 168 8 delayed delay VBN cord-310304-f28tjmi8 168 9 recovery recovery NN cord-310304-f28tjmi8 168 10 , , , cord-310304-f28tjmi8 168 11 respiratory respiratory JJ cord-310304-f28tjmi8 168 12 failure failure NN cord-310304-f28tjmi8 168 13 , , , cord-310304-f28tjmi8 168 14 septic septic JJ cord-310304-f28tjmi8 168 15 shock shock NN cord-310304-f28tjmi8 168 16 , , , cord-310304-f28tjmi8 168 17 or or CC cord-310304-f28tjmi8 168 18 MOD mod NN cord-310304-f28tjmi8 168 19 or or CC cord-310304-f28tjmi8 168 20 failure failure NN cord-310304-f28tjmi8 168 21 ( ( -LRB- cord-310304-f28tjmi8 168 22 Figure figure NN cord-310304-f28tjmi8 168 23 4 4 CD cord-310304-f28tjmi8 168 24 ) ) -RRB- cord-310304-f28tjmi8 168 25 . . . cord-310304-f28tjmi8 169 1 Hypothetical hypothetical JJ cord-310304-f28tjmi8 169 2 model model NN cord-310304-f28tjmi8 169 3 of of IN cord-310304-f28tjmi8 169 4 patients patient NNS cord-310304-f28tjmi8 169 5 with with IN cord-310304-f28tjmi8 169 6 pulmonary pulmonary JJ cord-310304-f28tjmi8 169 7 disease disease NN cord-310304-f28tjmi8 169 8 and and CC cord-310304-f28tjmi8 169 9 increased increase VBN cord-310304-f28tjmi8 169 10 risk risk NN cord-310304-f28tjmi8 169 11 for for IN cord-310304-f28tjmi8 169 12 complications complication NNS cord-310304-f28tjmi8 169 13 due due JJ cord-310304-f28tjmi8 169 14 to to IN cord-310304-f28tjmi8 169 15 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 169 16 . . . cord-310304-f28tjmi8 170 1 SARS SARS NNP cord-310304-f28tjmi8 170 2 - - HYPH cord-310304-f28tjmi8 170 3 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 170 4 infection infection NN cord-310304-f28tjmi8 170 5 via via IN cord-310304-f28tjmi8 170 6 ACE2 ACE2 NNP cord-310304-f28tjmi8 170 7 entry entry NN cord-310304-f28tjmi8 170 8 into into IN cord-310304-f28tjmi8 170 9 alveolar alveolar JJ cord-310304-f28tjmi8 170 10 epithelial epithelial JJ cord-310304-f28tjmi8 170 11 cells cell NNS cord-310304-f28tjmi8 170 12 in in IN cord-310304-f28tjmi8 170 13 patients patient NNS cord-310304-f28tjmi8 170 14 with with IN cord-310304-f28tjmi8 170 15 COPD COPD NNP cord-310304-f28tjmi8 170 16 who who WP cord-310304-f28tjmi8 170 17 smoke smoke VBP cord-310304-f28tjmi8 170 18 may may MD cord-310304-f28tjmi8 170 19 lead lead VB cord-310304-f28tjmi8 170 20 to to IN cord-310304-f28tjmi8 170 21 increased increase VBN cord-310304-f28tjmi8 170 22 surface surface NN cord-310304-f28tjmi8 170 23 - - HYPH cord-310304-f28tjmi8 170 24 expression expression NN cord-310304-f28tjmi8 170 25 ACE2 ACE2 NNP cord-310304-f28tjmi8 170 26 on on IN cord-310304-f28tjmi8 170 27 lung lung NN cord-310304-f28tjmi8 170 28 epithelium epithelium NN cord-310304-f28tjmi8 170 29 that that WDT cord-310304-f28tjmi8 170 30 may may MD cord-310304-f28tjmi8 170 31 increase increase VB cord-310304-f28tjmi8 170 32 the the DT cord-310304-f28tjmi8 170 33 rate rate NN cord-310304-f28tjmi8 170 34 of of IN cord-310304-f28tjmi8 170 35 infection infection NN cord-310304-f28tjmi8 170 36 in in IN cord-310304-f28tjmi8 170 37 the the DT cord-310304-f28tjmi8 170 38 lung lung NN cord-310304-f28tjmi8 170 39 and and CC cord-310304-f28tjmi8 170 40 contribute contribute VB cord-310304-f28tjmi8 170 41 to to IN cord-310304-f28tjmi8 170 42 higher high JJR cord-310304-f28tjmi8 170 43 viral viral JJ cord-310304-f28tjmi8 170 44 loads load NNS cord-310304-f28tjmi8 170 45 . . . cord-310304-f28tjmi8 171 1 Shown show VBN cord-310304-f28tjmi8 171 2 is be VBZ cord-310304-f28tjmi8 171 3 the the DT cord-310304-f28tjmi8 171 4 alveolar alveolar JJ cord-310304-f28tjmi8 171 5 organization organization NN cord-310304-f28tjmi8 171 6 and and CC cord-310304-f28tjmi8 171 7 resident resident NN cord-310304-f28tjmi8 171 8 cells cell NNS cord-310304-f28tjmi8 171 9 that that WDT cord-310304-f28tjmi8 171 10 include include VBP cord-310304-f28tjmi8 171 11 pneumocytes pneumocyte NNS cord-310304-f28tjmi8 171 12 Type Type NNP cord-310304-f28tjmi8 171 13 I I NNP cord-310304-f28tjmi8 171 14 , , , cord-310304-f28tjmi8 171 15 pneumocytes pneumocytes NNPS cord-310304-f28tjmi8 171 16 Type Type NNP cord-310304-f28tjmi8 171 17 II II NNP cord-310304-f28tjmi8 171 18 and and CC cord-310304-f28tjmi8 171 19 alveolar alveolar NN cord-310304-f28tjmi8 171 20 macrophages macrophage NNS cord-310304-f28tjmi8 171 21 . . . cord-310304-f28tjmi8 172 1 Elastic elastic JJ cord-310304-f28tjmi8 172 2 fibers fiber NNS cord-310304-f28tjmi8 172 3 are be VBP cord-310304-f28tjmi8 172 4 also also RB cord-310304-f28tjmi8 172 5 shown show VBN cord-310304-f28tjmi8 172 6 and and CC cord-310304-f28tjmi8 172 7 SARS SARS NNP cord-310304-f28tjmi8 172 8 - - HYPH cord-310304-f28tjmi8 172 9 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 172 10 particles particle NNS cord-310304-f28tjmi8 172 11 are be VBP cord-310304-f28tjmi8 172 12 shown show VBN cord-310304-f28tjmi8 172 13 as as IN cord-310304-f28tjmi8 172 14 blue blue JJ cord-310304-f28tjmi8 172 15 ovals oval NNS cord-310304-f28tjmi8 172 16 . . . cord-310304-f28tjmi8 173 1 Alveolar alveolar NN cord-310304-f28tjmi8 173 2 cells cell NNS cord-310304-f28tjmi8 173 3 pneumocytes pneumocyte NNS cord-310304-f28tjmi8 173 4 type type NN cord-310304-f28tjmi8 173 5 II II NNP cord-310304-f28tjmi8 173 6 are be VBP cord-310304-f28tjmi8 173 7 highly highly RB cord-310304-f28tjmi8 173 8 permissive permissive JJ cord-310304-f28tjmi8 173 9 for for IN cord-310304-f28tjmi8 173 10 SARS SARS NNP cord-310304-f28tjmi8 173 11 - - HYPH cord-310304-f28tjmi8 173 12 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 173 13 infection infection NN cord-310304-f28tjmi8 173 14 resulting result VBG cord-310304-f28tjmi8 173 15 in in IN cord-310304-f28tjmi8 173 16 alveolar alveolar JJ cord-310304-f28tjmi8 173 17 dysfunction dysfunction NN cord-310304-f28tjmi8 173 18 , , , cord-310304-f28tjmi8 173 19 inflammation inflammation NN cord-310304-f28tjmi8 173 20 , , , cord-310304-f28tjmi8 173 21 vascular vascular JJ cord-310304-f28tjmi8 173 22 leakage leakage NN cord-310304-f28tjmi8 173 23 , , , cord-310304-f28tjmi8 173 24 development development NN cord-310304-f28tjmi8 173 25 of of IN cord-310304-f28tjmi8 173 26 pulmonary pulmonary JJ cord-310304-f28tjmi8 173 27 emboli embolus NNS cord-310304-f28tjmi8 173 28 , , , cord-310304-f28tjmi8 173 29 and and CC cord-310304-f28tjmi8 173 30 acute acute JJ cord-310304-f28tjmi8 173 31 respiratory respiratory JJ cord-310304-f28tjmi8 173 32 distress distress NN cord-310304-f28tjmi8 173 33 from from IN cord-310304-f28tjmi8 173 34 poor poor JJ cord-310304-f28tjmi8 173 35 gas gas NN cord-310304-f28tjmi8 173 36 exchange exchange NN cord-310304-f28tjmi8 173 37 . . . cord-310304-f28tjmi8 174 1 Progressive progressive JJ cord-310304-f28tjmi8 174 2 viral viral JJ cord-310304-f28tjmi8 174 3 infection infection NN cord-310304-f28tjmi8 174 4 and and CC cord-310304-f28tjmi8 174 5 potential potential JJ cord-310304-f28tjmi8 174 6 cytokine cytokine NN cord-310304-f28tjmi8 174 7 storm storm NN cord-310304-f28tjmi8 174 8 leads lead VBZ cord-310304-f28tjmi8 174 9 to to IN cord-310304-f28tjmi8 174 10 pulmonary pulmonary JJ cord-310304-f28tjmi8 174 11 vascular vascular JJ cord-310304-f28tjmi8 174 12 leakage leakage NN cord-310304-f28tjmi8 174 13 , , , cord-310304-f28tjmi8 174 14 alveolar alveolar JJ cord-310304-f28tjmi8 174 15 edema edema NN cord-310304-f28tjmi8 174 16 , , , cord-310304-f28tjmi8 174 17 and and CC cord-310304-f28tjmi8 174 18 monocyte monocyte JJ cord-310304-f28tjmi8 174 19 infiltration infiltration NN cord-310304-f28tjmi8 174 20 at at IN cord-310304-f28tjmi8 174 21 sites site NNS cord-310304-f28tjmi8 174 22 of of IN cord-310304-f28tjmi8 174 23 infection infection NN cord-310304-f28tjmi8 174 24 , , , cord-310304-f28tjmi8 174 25 resulting result VBG cord-310304-f28tjmi8 174 26 in in IN cord-310304-f28tjmi8 174 27 reduced reduce VBN cord-310304-f28tjmi8 174 28 lung lung NN cord-310304-f28tjmi8 174 29 function function NN cord-310304-f28tjmi8 174 30 . . . cord-310304-f28tjmi8 175 1 Patients patient NNS cord-310304-f28tjmi8 175 2 often often RB cord-310304-f28tjmi8 175 3 require require VBP cord-310304-f28tjmi8 175 4 mechanical mechanical JJ cord-310304-f28tjmi8 175 5 ventilation ventilation NN cord-310304-f28tjmi8 175 6 increasing increase VBG cord-310304-f28tjmi8 175 7 the the DT cord-310304-f28tjmi8 175 8 risk risk NN cord-310304-f28tjmi8 175 9 of of IN cord-310304-f28tjmi8 175 10 delayed delay VBN cord-310304-f28tjmi8 175 11 recovery recovery NN cord-310304-f28tjmi8 175 12 , , , cord-310304-f28tjmi8 175 13 respiratory respiratory JJ cord-310304-f28tjmi8 175 14 failure failure NN cord-310304-f28tjmi8 175 15 , , , cord-310304-f28tjmi8 175 16 septic septic JJ cord-310304-f28tjmi8 175 17 shock shock NN cord-310304-f28tjmi8 175 18 , , , cord-310304-f28tjmi8 175 19 and and CC cord-310304-f28tjmi8 175 20 MOD mod NN cord-310304-f28tjmi8 175 21 or or CC cord-310304-f28tjmi8 175 22 failure failure NN cord-310304-f28tjmi8 175 23 . . . cord-310304-f28tjmi8 176 1 ARDS ARDS NNP cord-310304-f28tjmi8 176 2 ( ( -LRB- cord-310304-f28tjmi8 176 3 Acute acute JJ cord-310304-f28tjmi8 176 4 respiratory respiratory JJ cord-310304-f28tjmi8 176 5 distress distress NN cord-310304-f28tjmi8 176 6 syndrome syndrome NN cord-310304-f28tjmi8 176 7 ) ) -RRB- cord-310304-f28tjmi8 176 8 . . . cord-310304-f28tjmi8 177 1 infection infection NN cord-310304-f28tjmi8 177 2 via via IN cord-310304-f28tjmi8 177 3 ACE2 ACE2 NNP cord-310304-f28tjmi8 177 4 entry entry NN cord-310304-f28tjmi8 177 5 into into IN cord-310304-f28tjmi8 177 6 alveolar alveolar JJ cord-310304-f28tjmi8 177 7 epithelial epithelial JJ cord-310304-f28tjmi8 177 8 cells cell NNS cord-310304-f28tjmi8 177 9 in in IN cord-310304-f28tjmi8 177 10 patients patient NNS cord-310304-f28tjmi8 177 11 with with IN cord-310304-f28tjmi8 177 12 COPD COPD NNP cord-310304-f28tjmi8 177 13 who who WP cord-310304-f28tjmi8 177 14 smoke smoke VBP cord-310304-f28tjmi8 177 15 may may MD cord-310304-f28tjmi8 177 16 lead lead VB cord-310304-f28tjmi8 177 17 to to IN cord-310304-f28tjmi8 177 18 increased increase VBN cord-310304-f28tjmi8 177 19 surface surface NN cord-310304-f28tjmi8 177 20 - - HYPH cord-310304-f28tjmi8 177 21 expression expression NN cord-310304-f28tjmi8 177 22 ACE2 ACE2 NNP cord-310304-f28tjmi8 177 23 on on IN cord-310304-f28tjmi8 177 24 lung lung NN cord-310304-f28tjmi8 177 25 epithelium epithelium NN cord-310304-f28tjmi8 177 26 that that WDT cord-310304-f28tjmi8 177 27 may may MD cord-310304-f28tjmi8 177 28 increase increase VB cord-310304-f28tjmi8 177 29 the the DT cord-310304-f28tjmi8 177 30 rate rate NN cord-310304-f28tjmi8 177 31 of of IN cord-310304-f28tjmi8 177 32 infection infection NN cord-310304-f28tjmi8 177 33 in in IN cord-310304-f28tjmi8 177 34 the the DT cord-310304-f28tjmi8 177 35 lung lung NN cord-310304-f28tjmi8 177 36 and and CC cord-310304-f28tjmi8 177 37 contribute contribute VB cord-310304-f28tjmi8 177 38 to to IN cord-310304-f28tjmi8 177 39 higher high JJR cord-310304-f28tjmi8 177 40 viral viral JJ cord-310304-f28tjmi8 177 41 loads load NNS cord-310304-f28tjmi8 177 42 . . . cord-310304-f28tjmi8 178 1 Shown show VBN cord-310304-f28tjmi8 178 2 is be VBZ cord-310304-f28tjmi8 178 3 the the DT cord-310304-f28tjmi8 178 4 alveolar alveolar JJ cord-310304-f28tjmi8 178 5 organization organization NN cord-310304-f28tjmi8 178 6 and and CC cord-310304-f28tjmi8 178 7 resident resident NN cord-310304-f28tjmi8 178 8 cells cell NNS cord-310304-f28tjmi8 178 9 that that WDT cord-310304-f28tjmi8 178 10 include include VBP cord-310304-f28tjmi8 178 11 pneumocytes pneumocyte NNS cord-310304-f28tjmi8 178 12 Type Type NNP cord-310304-f28tjmi8 178 13 I I NNP cord-310304-f28tjmi8 178 14 , , , cord-310304-f28tjmi8 178 15 pneumocytes pneumocytes NNPS cord-310304-f28tjmi8 178 16 Type Type NNP cord-310304-f28tjmi8 178 17 II II NNP cord-310304-f28tjmi8 178 18 and and CC cord-310304-f28tjmi8 178 19 alveolar alveolar NN cord-310304-f28tjmi8 178 20 macrophages macrophage NNS cord-310304-f28tjmi8 178 21 . . . cord-310304-f28tjmi8 179 1 Elastic elastic JJ cord-310304-f28tjmi8 179 2 fibers fiber NNS cord-310304-f28tjmi8 179 3 are be VBP cord-310304-f28tjmi8 179 4 also also RB cord-310304-f28tjmi8 179 5 shown show VBN cord-310304-f28tjmi8 179 6 and and CC cord-310304-f28tjmi8 179 7 SARS SARS NNP cord-310304-f28tjmi8 179 8 - - HYPH cord-310304-f28tjmi8 179 9 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 179 10 particles particle NNS cord-310304-f28tjmi8 179 11 are be VBP cord-310304-f28tjmi8 179 12 shown show VBN cord-310304-f28tjmi8 179 13 as as IN cord-310304-f28tjmi8 179 14 blue blue JJ cord-310304-f28tjmi8 179 15 ovals oval NNS cord-310304-f28tjmi8 179 16 . . . cord-310304-f28tjmi8 180 1 Alveolar alveolar NN cord-310304-f28tjmi8 180 2 cells cell NNS cord-310304-f28tjmi8 180 3 pneumocytes pneumocyte NNS cord-310304-f28tjmi8 180 4 type type NN cord-310304-f28tjmi8 180 5 II II NNP cord-310304-f28tjmi8 180 6 are be VBP cord-310304-f28tjmi8 180 7 highly highly RB cord-310304-f28tjmi8 180 8 permissive permissive JJ cord-310304-f28tjmi8 180 9 for for IN cord-310304-f28tjmi8 180 10 SARS SARS NNP cord-310304-f28tjmi8 180 11 - - HYPH cord-310304-f28tjmi8 180 12 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 180 13 infection infection NN cord-310304-f28tjmi8 180 14 resulting result VBG cord-310304-f28tjmi8 180 15 in in IN cord-310304-f28tjmi8 180 16 alveolar alveolar JJ cord-310304-f28tjmi8 180 17 dysfunction dysfunction NN cord-310304-f28tjmi8 180 18 , , , cord-310304-f28tjmi8 180 19 inflammation inflammation NN cord-310304-f28tjmi8 180 20 , , , cord-310304-f28tjmi8 180 21 vascular vascular JJ cord-310304-f28tjmi8 180 22 leakage leakage NN cord-310304-f28tjmi8 180 23 , , , cord-310304-f28tjmi8 180 24 development development NN cord-310304-f28tjmi8 180 25 of of IN cord-310304-f28tjmi8 180 26 pulmonary pulmonary JJ cord-310304-f28tjmi8 180 27 emboli embolus NNS cord-310304-f28tjmi8 180 28 , , , cord-310304-f28tjmi8 180 29 and and CC cord-310304-f28tjmi8 180 30 acute acute JJ cord-310304-f28tjmi8 180 31 respiratory respiratory JJ cord-310304-f28tjmi8 180 32 distress distress NN cord-310304-f28tjmi8 180 33 from from IN cord-310304-f28tjmi8 180 34 poor poor JJ cord-310304-f28tjmi8 180 35 gas gas NN cord-310304-f28tjmi8 180 36 exchange exchange NN cord-310304-f28tjmi8 180 37 . . . cord-310304-f28tjmi8 181 1 Progressive progressive JJ cord-310304-f28tjmi8 181 2 viral viral JJ cord-310304-f28tjmi8 181 3 infection infection NN cord-310304-f28tjmi8 181 4 and and CC cord-310304-f28tjmi8 181 5 potential potential JJ cord-310304-f28tjmi8 181 6 cytokine cytokine NN cord-310304-f28tjmi8 181 7 storm storm NN cord-310304-f28tjmi8 181 8 leads lead VBZ cord-310304-f28tjmi8 181 9 to to IN cord-310304-f28tjmi8 181 10 pulmonary pulmonary JJ cord-310304-f28tjmi8 181 11 vascular vascular JJ cord-310304-f28tjmi8 181 12 leakage leakage NN cord-310304-f28tjmi8 181 13 , , , cord-310304-f28tjmi8 181 14 alveolar alveolar JJ cord-310304-f28tjmi8 181 15 edema edema NN cord-310304-f28tjmi8 181 16 , , , cord-310304-f28tjmi8 181 17 and and CC cord-310304-f28tjmi8 181 18 monocyte monocyte JJ cord-310304-f28tjmi8 181 19 infiltration infiltration NN cord-310304-f28tjmi8 181 20 at at IN cord-310304-f28tjmi8 181 21 sites site NNS cord-310304-f28tjmi8 181 22 of of IN cord-310304-f28tjmi8 181 23 infection infection NN cord-310304-f28tjmi8 181 24 , , , cord-310304-f28tjmi8 181 25 resulting result VBG cord-310304-f28tjmi8 181 26 in in IN cord-310304-f28tjmi8 181 27 reduced reduce VBN cord-310304-f28tjmi8 181 28 lung lung NN cord-310304-f28tjmi8 181 29 function function NN cord-310304-f28tjmi8 181 30 . . . cord-310304-f28tjmi8 182 1 Patients patient NNS cord-310304-f28tjmi8 182 2 often often RB cord-310304-f28tjmi8 182 3 require require VBP cord-310304-f28tjmi8 182 4 mechanical mechanical JJ cord-310304-f28tjmi8 182 5 ventilation ventilation NN cord-310304-f28tjmi8 182 6 increasing increase VBG cord-310304-f28tjmi8 182 7 the the DT cord-310304-f28tjmi8 182 8 risk risk NN cord-310304-f28tjmi8 182 9 of of IN cord-310304-f28tjmi8 182 10 delayed delay VBN cord-310304-f28tjmi8 182 11 recovery recovery NN cord-310304-f28tjmi8 182 12 , , , cord-310304-f28tjmi8 182 13 respiratory respiratory JJ cord-310304-f28tjmi8 182 14 failure failure NN cord-310304-f28tjmi8 182 15 , , , cord-310304-f28tjmi8 182 16 septic septic JJ cord-310304-f28tjmi8 182 17 shock shock NN cord-310304-f28tjmi8 182 18 , , , cord-310304-f28tjmi8 182 19 and and CC cord-310304-f28tjmi8 182 20 MOD mod NN cord-310304-f28tjmi8 182 21 or or CC cord-310304-f28tjmi8 182 22 failure failure NN cord-310304-f28tjmi8 182 23 . . . cord-310304-f28tjmi8 183 1 ARDS ARDS NNP cord-310304-f28tjmi8 183 2 ( ( -LRB- cord-310304-f28tjmi8 183 3 Acute acute JJ cord-310304-f28tjmi8 183 4 respiratory respiratory JJ cord-310304-f28tjmi8 183 5 distress distress NN cord-310304-f28tjmi8 183 6 syndrome syndrome NN cord-310304-f28tjmi8 183 7 ) ) -RRB- cord-310304-f28tjmi8 183 8 . . . cord-310304-f28tjmi8 184 1 Differential differential JJ cord-310304-f28tjmi8 184 2 expression expression NN cord-310304-f28tjmi8 184 3 of of IN cord-310304-f28tjmi8 184 4 ACE2 ACE2 NNP cord-310304-f28tjmi8 184 5 may may MD cord-310304-f28tjmi8 184 6 help help VB cord-310304-f28tjmi8 184 7 to to TO cord-310304-f28tjmi8 184 8 explain explain VB cord-310304-f28tjmi8 184 9 the the DT cord-310304-f28tjmi8 184 10 discrepancy discrepancy NN cord-310304-f28tjmi8 184 11 in in IN cord-310304-f28tjmi8 184 12 viral viral JJ cord-310304-f28tjmi8 184 13 pathology pathology NN cord-310304-f28tjmi8 184 14 associated associate VBN cord-310304-f28tjmi8 184 15 with with IN cord-310304-f28tjmi8 184 16 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 184 17 . . . cord-310304-f28tjmi8 185 1 The the DT cord-310304-f28tjmi8 185 2 production production NN cord-310304-f28tjmi8 185 3 of of IN cord-310304-f28tjmi8 185 4 ACE2 ACE2 NNP cord-310304-f28tjmi8 185 5 among among IN cord-310304-f28tjmi8 185 6 minority minority NN cord-310304-f28tjmi8 185 7 populations population NNS cord-310304-f28tjmi8 185 8 who who WP cord-310304-f28tjmi8 185 9 smoke smoke VBP cord-310304-f28tjmi8 185 10 or or CC cord-310304-f28tjmi8 185 11 have have VB cord-310304-f28tjmi8 185 12 COPD COPD NNP cord-310304-f28tjmi8 185 13 may may MD cord-310304-f28tjmi8 185 14 partially partially RB cord-310304-f28tjmi8 185 15 explain explain VB cord-310304-f28tjmi8 185 16 the the DT cord-310304-f28tjmi8 185 17 differences difference NNS cord-310304-f28tjmi8 185 18 in in IN cord-310304-f28tjmi8 185 19 COVID-19 covid-19 JJ cord-310304-f28tjmi8 185 20 rates rate NNS cord-310304-f28tjmi8 185 21 of of IN cord-310304-f28tjmi8 185 22 morbidity morbidity NN cord-310304-f28tjmi8 185 23 and and CC cord-310304-f28tjmi8 185 24 mortality mortality NN cord-310304-f28tjmi8 185 25 among among IN cord-310304-f28tjmi8 185 26 AAs aas NN cord-310304-f28tjmi8 185 27 compared compare VBN cord-310304-f28tjmi8 185 28 with with IN cord-310304-f28tjmi8 185 29 NHWs nhws NN cord-310304-f28tjmi8 185 30 . . . cord-310304-f28tjmi8 186 1 Leung Leung NNP cord-310304-f28tjmi8 186 2 et et NNP cord-310304-f28tjmi8 186 3 al al NNP cord-310304-f28tjmi8 186 4 . . . cord-310304-f28tjmi8 187 1 examined examine VBN cord-310304-f28tjmi8 187 2 gene gene NN cord-310304-f28tjmi8 187 3 expression expression NN cord-310304-f28tjmi8 187 4 levels level NNS cord-310304-f28tjmi8 187 5 of of IN cord-310304-f28tjmi8 187 6 ACE2 ACE2 NNP cord-310304-f28tjmi8 187 7 in in IN cord-310304-f28tjmi8 187 8 the the DT cord-310304-f28tjmi8 187 9 airways airway NNS cord-310304-f28tjmi8 187 10 of of IN cord-310304-f28tjmi8 187 11 individuals individual NNS cord-310304-f28tjmi8 187 12 with with IN cord-310304-f28tjmi8 187 13 and and CC cord-310304-f28tjmi8 187 14 without without IN cord-310304-f28tjmi8 187 15 COPD COPD NNP cord-310304-f28tjmi8 187 16 and and CC cord-310304-f28tjmi8 187 17 found find VBD cord-310304-f28tjmi8 187 18 that that IN cord-310304-f28tjmi8 187 19 active active JJ cord-310304-f28tjmi8 187 20 cigarette cigarette NN cord-310304-f28tjmi8 187 21 smoking smoking NN cord-310304-f28tjmi8 187 22 and and CC cord-310304-f28tjmi8 187 23 COPD COPD NNP cord-310304-f28tjmi8 187 24 upregulate upregulate VBD cord-310304-f28tjmi8 187 25 ACE2 ACE2 NNP cord-310304-f28tjmi8 187 26 expression expression NN cord-310304-f28tjmi8 187 27 in in IN cord-310304-f28tjmi8 187 28 lower low JJR cord-310304-f28tjmi8 187 29 airways airway NNS cord-310304-f28tjmi8 187 30 and and CC cord-310304-f28tjmi8 187 31 could could MD cord-310304-f28tjmi8 187 32 contribute contribute VB cord-310304-f28tjmi8 187 33 to to IN cord-310304-f28tjmi8 187 34 the the DT cord-310304-f28tjmi8 187 35 difference difference NN cord-310304-f28tjmi8 187 36 in in IN cord-310304-f28tjmi8 187 37 disease disease NN cord-310304-f28tjmi8 187 38 burden burden NN cord-310304-f28tjmi8 187 39 observed observe VBN cord-310304-f28tjmi8 187 40 among among IN cord-310304-f28tjmi8 187 41 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 187 42 patients patient NNS cord-310304-f28tjmi8 187 43 [ [ -LRB- cord-310304-f28tjmi8 187 44 77 77 CD cord-310304-f28tjmi8 187 45 ] ] -RRB- cord-310304-f28tjmi8 187 46 . . . cord-310304-f28tjmi8 188 1 These these DT cord-310304-f28tjmi8 188 2 findings finding NNS cord-310304-f28tjmi8 188 3 were be VBD cord-310304-f28tjmi8 188 4 supported support VBN cord-310304-f28tjmi8 188 5 in in IN cord-310304-f28tjmi8 188 6 a a DT cord-310304-f28tjmi8 188 7 rat rat NN cord-310304-f28tjmi8 188 8 model model NN cord-310304-f28tjmi8 188 9 that that WDT cord-310304-f28tjmi8 188 10 showed show VBD cord-310304-f28tjmi8 188 11 smoke smoke NN cord-310304-f28tjmi8 188 12 exposure exposure NN cord-310304-f28tjmi8 188 13 resulted result VBD cord-310304-f28tjmi8 188 14 in in IN cord-310304-f28tjmi8 188 15 increased increase VBN cord-310304-f28tjmi8 188 16 expression expression NN cord-310304-f28tjmi8 188 17 and and CC cord-310304-f28tjmi8 188 18 activity activity NN cord-310304-f28tjmi8 188 19 of of IN cord-310304-f28tjmi8 188 20 ACE2 ACE2 NNP cord-310304-f28tjmi8 188 21 in in IN cord-310304-f28tjmi8 188 22 the the DT cord-310304-f28tjmi8 188 23 airways airway NNS cord-310304-f28tjmi8 188 24 [ [ -LRB- cord-310304-f28tjmi8 188 25 78 78 CD cord-310304-f28tjmi8 188 26 ] ] -RRB- cord-310304-f28tjmi8 188 27 . . . cord-310304-f28tjmi8 189 1 Individuals individual NNS cord-310304-f28tjmi8 189 2 with with IN cord-310304-f28tjmi8 189 3 uncontrolled uncontrolled JJ cord-310304-f28tjmi8 189 4 asthma asthma NN cord-310304-f28tjmi8 189 5 also also RB cord-310304-f28tjmi8 189 6 appear appear VBP cord-310304-f28tjmi8 189 7 to to TO cord-310304-f28tjmi8 189 8 be be VB cord-310304-f28tjmi8 189 9 at at IN cord-310304-f28tjmi8 189 10 increased increase VBN cord-310304-f28tjmi8 189 11 risk risk NN cord-310304-f28tjmi8 189 12 of of IN cord-310304-f28tjmi8 189 13 a a DT cord-310304-f28tjmi8 189 14 more more RBR cord-310304-f28tjmi8 189 15 severe severe JJ cord-310304-f28tjmi8 189 16 course course NN cord-310304-f28tjmi8 189 17 of of IN cord-310304-f28tjmi8 189 18 COVID-19 covid-19 JJ cord-310304-f28tjmi8 189 19 infection infection NN cord-310304-f28tjmi8 189 20 [ [ -LRB- cord-310304-f28tjmi8 189 21 79 79 CD cord-310304-f28tjmi8 189 22 ] ] -RRB- cord-310304-f28tjmi8 189 23 . . . cord-310304-f28tjmi8 190 1 Lung lung NN cord-310304-f28tjmi8 190 2 function function NN cord-310304-f28tjmi8 190 3 tests test NNS cord-310304-f28tjmi8 190 4 and and CC cord-310304-f28tjmi8 190 5 the the DT cord-310304-f28tjmi8 190 6 use use NN cord-310304-f28tjmi8 190 7 of of IN cord-310304-f28tjmi8 190 8 nebulizers nebulizer NNS cord-310304-f28tjmi8 190 9 as as IN cord-310304-f28tjmi8 190 10 part part NN cord-310304-f28tjmi8 190 11 of of IN cord-310304-f28tjmi8 190 12 COPD COPD NNP cord-310304-f28tjmi8 190 13 and and CC cord-310304-f28tjmi8 190 14 asthma asthma NN cord-310304-f28tjmi8 190 15 management management NN cord-310304-f28tjmi8 190 16 should should MD cord-310304-f28tjmi8 190 17 be be VB cord-310304-f28tjmi8 190 18 performed perform VBN cord-310304-f28tjmi8 190 19 with with IN cord-310304-f28tjmi8 190 20 caution caution NN cord-310304-f28tjmi8 190 21 due due IN cord-310304-f28tjmi8 190 22 to to IN cord-310304-f28tjmi8 190 23 the the DT cord-310304-f28tjmi8 190 24 risk risk NN cord-310304-f28tjmi8 190 25 of of IN cord-310304-f28tjmi8 190 26 virus virus NN cord-310304-f28tjmi8 190 27 aerosolization aerosolization NN cord-310304-f28tjmi8 190 28 and and CC cord-310304-f28tjmi8 190 29 potential potential JJ cord-310304-f28tjmi8 190 30 transmission transmission NN cord-310304-f28tjmi8 190 31 during during IN cord-310304-f28tjmi8 190 32 these these DT cord-310304-f28tjmi8 190 33 procedures procedure NNS cord-310304-f28tjmi8 190 34 [ [ -LRB- cord-310304-f28tjmi8 190 35 79 79 CD cord-310304-f28tjmi8 190 36 ] ] -RRB- cord-310304-f28tjmi8 190 37 . . . cord-310304-f28tjmi8 191 1 Disparities disparity NNS cord-310304-f28tjmi8 191 2 in in IN cord-310304-f28tjmi8 191 3 T2D t2d CD cord-310304-f28tjmi8 191 4 among among IN cord-310304-f28tjmi8 191 5 minority minority NN cord-310304-f28tjmi8 191 6 adults adult NNS cord-310304-f28tjmi8 191 7 have have VBP cord-310304-f28tjmi8 191 8 been be VBN cord-310304-f28tjmi8 191 9 pervasive pervasive JJ cord-310304-f28tjmi8 191 10 in in IN cord-310304-f28tjmi8 191 11 diabetes diabetes NN cord-310304-f28tjmi8 191 12 complications complication NNS cord-310304-f28tjmi8 191 13 , , , cord-310304-f28tjmi8 191 14 glycemic glycemic NN cord-310304-f28tjmi8 191 15 control control NN cord-310304-f28tjmi8 191 16 , , , cord-310304-f28tjmi8 191 17 and and CC cord-310304-f28tjmi8 191 18 diabetes diabetes NN cord-310304-f28tjmi8 191 19 care care VBP cord-310304-f28tjmi8 191 20 [ [ -LRB- cord-310304-f28tjmi8 191 21 80 80 CD cord-310304-f28tjmi8 191 22 ] ] -RRB- cord-310304-f28tjmi8 191 23 . . . cord-310304-f28tjmi8 192 1 Glycemic glycemic NN cord-310304-f28tjmi8 192 2 control control NN cord-310304-f28tjmi8 192 3 in in IN cord-310304-f28tjmi8 192 4 all all DT cord-310304-f28tjmi8 192 5 patients patient NNS cord-310304-f28tjmi8 192 6 with with IN cord-310304-f28tjmi8 192 7 diabetes diabetes NN cord-310304-f28tjmi8 192 8 is be VBZ cord-310304-f28tjmi8 192 9 critical critical JJ cord-310304-f28tjmi8 192 10 for for IN cord-310304-f28tjmi8 192 11 avoiding avoid VBG cord-310304-f28tjmi8 192 12 complications complication NNS cord-310304-f28tjmi8 192 13 such such JJ cord-310304-f28tjmi8 192 14 as as IN cord-310304-f28tjmi8 192 15 CKD CKD NNP cord-310304-f28tjmi8 192 16 , , , cord-310304-f28tjmi8 192 17 CVD CVD NNP cord-310304-f28tjmi8 192 18 , , , cord-310304-f28tjmi8 192 19 and and CC cord-310304-f28tjmi8 192 20 diabetes diabetes NN cord-310304-f28tjmi8 192 21 - - HYPH cord-310304-f28tjmi8 192 22 related relate VBN cord-310304-f28tjmi8 192 23 eye eye NN cord-310304-f28tjmi8 192 24 disease disease NN cord-310304-f28tjmi8 192 25 . . . cord-310304-f28tjmi8 193 1 It -PRON- PRP cord-310304-f28tjmi8 193 2 is be VBZ cord-310304-f28tjmi8 193 3 projected project VBN cord-310304-f28tjmi8 193 4 that that IN cord-310304-f28tjmi8 193 5 racial racial JJ cord-310304-f28tjmi8 193 6 and and CC cord-310304-f28tjmi8 193 7 ethnic ethnic JJ cord-310304-f28tjmi8 193 8 disparities disparity NNS cord-310304-f28tjmi8 193 9 in in IN cord-310304-f28tjmi8 193 10 T2D t2d DT cord-310304-f28tjmi8 193 11 prevalence prevalence NN cord-310304-f28tjmi8 193 12 will will MD cord-310304-f28tjmi8 193 13 persist persist VB cord-310304-f28tjmi8 193 14 until until IN cord-310304-f28tjmi8 193 15 2050 2050 CD cord-310304-f28tjmi8 193 16 [ [ -LRB- cord-310304-f28tjmi8 193 17 81 81 CD cord-310304-f28tjmi8 193 18 ] ] -RRB- cord-310304-f28tjmi8 193 19 . . . cord-310304-f28tjmi8 194 1 One one CD cord-310304-f28tjmi8 194 2 of of IN cord-310304-f28tjmi8 194 3 the the DT cord-310304-f28tjmi8 194 4 most most RBS cord-310304-f28tjmi8 194 5 significant significant JJ cord-310304-f28tjmi8 194 6 challenges challenge NNS cord-310304-f28tjmi8 194 7 in in IN cord-310304-f28tjmi8 194 8 mitigating mitigate VBG cord-310304-f28tjmi8 194 9 the the DT cord-310304-f28tjmi8 194 10 effects effect NNS cord-310304-f28tjmi8 194 11 of of IN cord-310304-f28tjmi8 194 12 diabetes diabete NNS cord-310304-f28tjmi8 194 13 on on IN cord-310304-f28tjmi8 194 14 the the DT cord-310304-f28tjmi8 194 15 health health NN cord-310304-f28tjmi8 194 16 and and CC cord-310304-f28tjmi8 194 17 wellness wellness NN cord-310304-f28tjmi8 194 18 of of IN cord-310304-f28tjmi8 194 19 minority minority NN cord-310304-f28tjmi8 194 20 populations population NNS cord-310304-f28tjmi8 194 21 in in IN cord-310304-f28tjmi8 194 22 the the DT cord-310304-f28tjmi8 194 23 US US NNP cord-310304-f28tjmi8 194 24 is be VBZ cord-310304-f28tjmi8 194 25 improving improve VBG cord-310304-f28tjmi8 194 26 basic basic JJ cord-310304-f28tjmi8 194 27 social social JJ cord-310304-f28tjmi8 194 28 determinants determinant NNS cord-310304-f28tjmi8 194 29 of of IN cord-310304-f28tjmi8 194 30 health health NN cord-310304-f28tjmi8 194 31 , , , cord-310304-f28tjmi8 194 32 including include VBG cord-310304-f28tjmi8 194 33 low low JJ cord-310304-f28tjmi8 194 34 socioeconomic socioeconomic JJ cord-310304-f28tjmi8 194 35 status status NN cord-310304-f28tjmi8 194 36 , , , cord-310304-f28tjmi8 194 37 poor poor JJ cord-310304-f28tjmi8 194 38 access access NN cord-310304-f28tjmi8 194 39 to to IN cord-310304-f28tjmi8 194 40 educational educational JJ cord-310304-f28tjmi8 194 41 opportunities opportunity NNS cord-310304-f28tjmi8 194 42 , , , cord-310304-f28tjmi8 194 43 conditions condition NNS cord-310304-f28tjmi8 194 44 of of IN cord-310304-f28tjmi8 194 45 poverty poverty NN cord-310304-f28tjmi8 194 46 , , , cord-310304-f28tjmi8 194 47 excess excess JJ cord-310304-f28tjmi8 194 48 life life NN cord-310304-f28tjmi8 194 49 stressors stressor NNS cord-310304-f28tjmi8 194 50 , , , cord-310304-f28tjmi8 194 51 poor poor JJ cord-310304-f28tjmi8 194 52 health health NN cord-310304-f28tjmi8 194 53 knowledge knowledge NN cord-310304-f28tjmi8 194 54 , , , cord-310304-f28tjmi8 194 55 and and CC cord-310304-f28tjmi8 194 56 limited limited JJ cord-310304-f28tjmi8 194 57 access access NN cord-310304-f28tjmi8 194 58 to to IN cord-310304-f28tjmi8 194 59 quality quality NN cord-310304-f28tjmi8 194 60 and and CC cord-310304-f28tjmi8 194 61 affordable affordable JJ cord-310304-f28tjmi8 194 62 health health NN cord-310304-f28tjmi8 194 63 care care NN cord-310304-f28tjmi8 194 64 . . . cord-310304-f28tjmi8 195 1 Strategies strategy NNS cord-310304-f28tjmi8 195 2 to to TO cord-310304-f28tjmi8 195 3 mitigate mitigate VB cord-310304-f28tjmi8 195 4 diabetes diabetes NN cord-310304-f28tjmi8 195 5 among among IN cord-310304-f28tjmi8 195 6 minority minority NN cord-310304-f28tjmi8 195 7 populations population NNS cord-310304-f28tjmi8 195 8 at at IN cord-310304-f28tjmi8 195 9 greater great JJR cord-310304-f28tjmi8 195 10 risk risk NN cord-310304-f28tjmi8 195 11 for for IN cord-310304-f28tjmi8 195 12 severe severe JJ cord-310304-f28tjmi8 195 13 COVID-19 covid-19 JJ cord-310304-f28tjmi8 195 14 disease disease NN cord-310304-f28tjmi8 195 15 would would MD cord-310304-f28tjmi8 195 16 involve involve VB cord-310304-f28tjmi8 195 17 improving improve VBG cord-310304-f28tjmi8 195 18 glycemic glycemic JJ cord-310304-f28tjmi8 195 19 control control NN cord-310304-f28tjmi8 195 20 among among IN cord-310304-f28tjmi8 195 21 AAs AAs NNP cord-310304-f28tjmi8 195 22 and and CC cord-310304-f28tjmi8 195 23 H H NNP cord-310304-f28tjmi8 195 24 / / SYM cord-310304-f28tjmi8 195 25 Ls Ls NNP cord-310304-f28tjmi8 195 26 , , , cord-310304-f28tjmi8 195 27 which which WDT cord-310304-f28tjmi8 195 28 is be VBZ cord-310304-f28tjmi8 195 29 a a DT cord-310304-f28tjmi8 195 30 major major JJ cord-310304-f28tjmi8 195 31 problem problem NN cord-310304-f28tjmi8 195 32 [ [ -LRB- cord-310304-f28tjmi8 195 33 82 82 CD cord-310304-f28tjmi8 195 34 ] ] -RRB- cord-310304-f28tjmi8 195 35 . . . cord-310304-f28tjmi8 196 1 Management management NN cord-310304-f28tjmi8 196 2 of of IN cord-310304-f28tjmi8 196 3 hypertension hypertension NN cord-310304-f28tjmi8 196 4 has have VBZ cord-310304-f28tjmi8 196 5 been be VBN cord-310304-f28tjmi8 196 6 problematic problematic JJ cord-310304-f28tjmi8 196 7 among among IN cord-310304-f28tjmi8 196 8 minority minority NN cord-310304-f28tjmi8 196 9 populations population NNS cord-310304-f28tjmi8 196 10 with with IN cord-310304-f28tjmi8 196 11 diabetes diabete NNS cord-310304-f28tjmi8 196 12 . . . cord-310304-f28tjmi8 197 1 It -PRON- PRP cord-310304-f28tjmi8 197 2 has have VBZ cord-310304-f28tjmi8 197 3 been be VBN cord-310304-f28tjmi8 197 4 reported report VBN cord-310304-f28tjmi8 197 5 that that IN cord-310304-f28tjmi8 197 6 71 71 CD cord-310304-f28tjmi8 197 7 % % NN cord-310304-f28tjmi8 197 8 of of IN cord-310304-f28tjmi8 197 9 adults adult NNS cord-310304-f28tjmi8 197 10 with with IN cord-310304-f28tjmi8 197 11 diabetes diabete NNS cord-310304-f28tjmi8 197 12 have have VBP cord-310304-f28tjmi8 197 13 high high JJ cord-310304-f28tjmi8 197 14 blood blood NN cord-310304-f28tjmi8 197 15 pressure pressure NN cord-310304-f28tjmi8 197 16 , , , cord-310304-f28tjmi8 197 17 and and CC cord-310304-f28tjmi8 197 18 blood blood NN cord-310304-f28tjmi8 197 19 pressure pressure NN cord-310304-f28tjmi8 197 20 control control NN cord-310304-f28tjmi8 197 21 among among IN cord-310304-f28tjmi8 197 22 diabetics diabetic NNS cord-310304-f28tjmi8 197 23 is be VBZ cord-310304-f28tjmi8 197 24 essential essential JJ cord-310304-f28tjmi8 197 25 to to TO cord-310304-f28tjmi8 197 26 reduce reduce VB cord-310304-f28tjmi8 197 27 the the DT cord-310304-f28tjmi8 197 28 risk risk NN cord-310304-f28tjmi8 197 29 of of IN cord-310304-f28tjmi8 197 30 developing develop VBG cord-310304-f28tjmi8 197 31 retinopathy retinopathy NN cord-310304-f28tjmi8 197 32 and and CC cord-310304-f28tjmi8 197 33 neuropathy neuropathy NN cord-310304-f28tjmi8 197 34 associated associate VBN cord-310304-f28tjmi8 197 35 with with IN cord-310304-f28tjmi8 197 36 diabetes diabete NNS cord-310304-f28tjmi8 197 37 [ [ -LRB- cord-310304-f28tjmi8 197 38 83 83 CD cord-310304-f28tjmi8 197 39 ] ] -RRB- cord-310304-f28tjmi8 197 40 . . . cord-310304-f28tjmi8 198 1 AAs aa NNS cord-310304-f28tjmi8 198 2 are be VBP cord-310304-f28tjmi8 198 3 more more RBR cord-310304-f28tjmi8 198 4 likely likely JJ cord-310304-f28tjmi8 198 5 to to TO cord-310304-f28tjmi8 198 6 have have VB cord-310304-f28tjmi8 198 7 significantly significantly RB cord-310304-f28tjmi8 198 8 higher high JJR cord-310304-f28tjmi8 198 9 , , , cord-310304-f28tjmi8 198 10 uncontrolled uncontrolled JJ cord-310304-f28tjmi8 198 11 blood blood NN cord-310304-f28tjmi8 198 12 pressure pressure NN cord-310304-f28tjmi8 198 13 than than IN cord-310304-f28tjmi8 198 14 NHWs NHWs NNP cord-310304-f28tjmi8 198 15 [ [ -LRB- cord-310304-f28tjmi8 198 16 83 83 CD cord-310304-f28tjmi8 198 17 ] ] -RRB- cord-310304-f28tjmi8 198 18 . . . cord-310304-f28tjmi8 199 1 Obesity obesity NN cord-310304-f28tjmi8 199 2 and and CC cord-310304-f28tjmi8 199 3 a a DT cord-310304-f28tjmi8 199 4 sedentary sedentary JJ cord-310304-f28tjmi8 199 5 lifestyle lifestyle NN cord-310304-f28tjmi8 199 6 should should MD cord-310304-f28tjmi8 199 7 be be VB cord-310304-f28tjmi8 199 8 avoided avoid VBN cord-310304-f28tjmi8 199 9 among among IN cord-310304-f28tjmi8 199 10 diabetics diabetic NNS cord-310304-f28tjmi8 199 11 [ [ -LRB- cord-310304-f28tjmi8 199 12 83 83 CD cord-310304-f28tjmi8 199 13 ] ] -RRB- cord-310304-f28tjmi8 199 14 . . . cord-310304-f28tjmi8 200 1 The the DT cord-310304-f28tjmi8 200 2 increased increase VBN cord-310304-f28tjmi8 200 3 burden burden NN cord-310304-f28tjmi8 200 4 of of IN cord-310304-f28tjmi8 200 5 diabetes diabetes NN cord-310304-f28tjmi8 200 6 among among IN cord-310304-f28tjmi8 200 7 racial racial JJ cord-310304-f28tjmi8 200 8 and and CC cord-310304-f28tjmi8 200 9 ethnic ethnic JJ cord-310304-f28tjmi8 200 10 minorities minority NNS cord-310304-f28tjmi8 200 11 . . . cord-310304-f28tjmi8 201 1 Diabetes diabetes NN cord-310304-f28tjmi8 201 2 is be VBZ cord-310304-f28tjmi8 201 3 higher high JJR cord-310304-f28tjmi8 201 4 among among IN cord-310304-f28tjmi8 201 5 Black black JJ cord-310304-f28tjmi8 201 6 or or CC cord-310304-f28tjmi8 201 7 African african JJ cord-310304-f28tjmi8 201 8 American American NNP cord-310304-f28tjmi8 201 9 , , , cord-310304-f28tjmi8 201 10 H H NNP cord-310304-f28tjmi8 201 11 / / SYM cord-310304-f28tjmi8 201 12 Ls Ls NNP cord-310304-f28tjmi8 201 13 , , , cord-310304-f28tjmi8 201 14 and and CC cord-310304-f28tjmi8 201 15 American american JJ cord-310304-f28tjmi8 201 16 Indian indian JJ cord-310304-f28tjmi8 201 17 individuals individual NNS cord-310304-f28tjmi8 201 18 as as IN cord-310304-f28tjmi8 201 19 compared compare VBN cord-310304-f28tjmi8 201 20 to to IN cord-310304-f28tjmi8 201 21 NHW NHW NNP cord-310304-f28tjmi8 201 22 [ [ -LRB- cord-310304-f28tjmi8 201 23 84 84 CD cord-310304-f28tjmi8 201 24 ] ] -RRB- cord-310304-f28tjmi8 201 25 . . . cord-310304-f28tjmi8 202 1 AAs aas JJ cord-310304-f28tjmi8 202 2 experiencing experience VBG cord-310304-f28tjmi8 202 3 household household NN cord-310304-f28tjmi8 202 4 or or CC cord-310304-f28tjmi8 202 5 neighborhood neighborhood NN cord-310304-f28tjmi8 202 6 - - HYPH cord-310304-f28tjmi8 202 7 level level NN cord-310304-f28tjmi8 202 8 poverty poverty NN cord-310304-f28tjmi8 202 9 are be VBP cord-310304-f28tjmi8 202 10 at at IN cord-310304-f28tjmi8 202 11 a a DT cord-310304-f28tjmi8 202 12 higher high JJR cord-310304-f28tjmi8 202 13 risk risk NN cord-310304-f28tjmi8 202 14 of of IN cord-310304-f28tjmi8 202 15 developing develop VBG cord-310304-f28tjmi8 202 16 diabetes diabete NNS cord-310304-f28tjmi8 202 17 [ [ -LRB- cord-310304-f28tjmi8 202 18 84 84 CD cord-310304-f28tjmi8 202 19 ] ] -RRB- cord-310304-f28tjmi8 202 20 . . . cord-310304-f28tjmi8 203 1 The the DT cord-310304-f28tjmi8 203 2 rates rate NNS cord-310304-f28tjmi8 203 3 of of IN cord-310304-f28tjmi8 203 4 diabetes diabete NNS cord-310304-f28tjmi8 203 5 in in IN cord-310304-f28tjmi8 203 6 the the DT cord-310304-f28tjmi8 203 7 Southern Southern NNP cord-310304-f28tjmi8 203 8 U.S. U.S. NNP cord-310304-f28tjmi8 203 9 is be VBZ cord-310304-f28tjmi8 203 10 higher high JJR cord-310304-f28tjmi8 203 11 than than IN cord-310304-f28tjmi8 203 12 the the DT cord-310304-f28tjmi8 203 13 national national JJ cord-310304-f28tjmi8 203 14 average average NN cord-310304-f28tjmi8 203 15 [ [ -LRB- cord-310304-f28tjmi8 203 16 85 85 CD cord-310304-f28tjmi8 203 17 ] ] -RRB- cord-310304-f28tjmi8 203 18 . . . cord-310304-f28tjmi8 204 1 This this DT cord-310304-f28tjmi8 204 2 will will MD cord-310304-f28tjmi8 204 3 require require VB cord-310304-f28tjmi8 204 4 overall overall JJ cord-310304-f28tjmi8 204 5 improvements improvement NNS cord-310304-f28tjmi8 204 6 in in IN cord-310304-f28tjmi8 204 7 social social JJ cord-310304-f28tjmi8 204 8 determinants determinant NNS cord-310304-f28tjmi8 204 9 of of IN cord-310304-f28tjmi8 204 10 health health NN cord-310304-f28tjmi8 204 11 that that WDT cord-310304-f28tjmi8 204 12 tend tend VBP cord-310304-f28tjmi8 204 13 to to TO cord-310304-f28tjmi8 204 14 predispose predispose VB cord-310304-f28tjmi8 204 15 these these DT cord-310304-f28tjmi8 204 16 populations population NNS cord-310304-f28tjmi8 204 17 to to IN cord-310304-f28tjmi8 204 18 the the DT cord-310304-f28tjmi8 204 19 worst bad JJS cord-310304-f28tjmi8 204 20 diabetes diabetes NN cord-310304-f28tjmi8 204 21 outcomes outcome NNS cord-310304-f28tjmi8 204 22 often often RB cord-310304-f28tjmi8 204 23 superimposed superimpose VBN cord-310304-f28tjmi8 204 24 on on IN cord-310304-f28tjmi8 204 25 the the DT cord-310304-f28tjmi8 204 26 pathogenesis pathogenesis NN cord-310304-f28tjmi8 204 27 of of IN cord-310304-f28tjmi8 204 28 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 204 29 disease disease NN cord-310304-f28tjmi8 204 30 burden burden NN cord-310304-f28tjmi8 204 31 . . . cord-310304-f28tjmi8 205 1 Among among IN cord-310304-f28tjmi8 205 2 racial racial JJ cord-310304-f28tjmi8 205 3 and and CC cord-310304-f28tjmi8 205 4 ethnic ethnic JJ cord-310304-f28tjmi8 205 5 minorities minority NNS cord-310304-f28tjmi8 205 6 , , , cord-310304-f28tjmi8 205 7 hypertension hypertension NN cord-310304-f28tjmi8 205 8 prevalence prevalence NN cord-310304-f28tjmi8 205 9 in in IN cord-310304-f28tjmi8 205 10 the the DT cord-310304-f28tjmi8 205 11 US US NNP cord-310304-f28tjmi8 205 12 is be VBZ cord-310304-f28tjmi8 205 13 highest high JJS cord-310304-f28tjmi8 205 14 among among IN cord-310304-f28tjmi8 205 15 AAs AAs NNP cord-310304-f28tjmi8 205 16 , , , cord-310304-f28tjmi8 205 17 who who WP cord-310304-f28tjmi8 205 18 have have VBP cord-310304-f28tjmi8 205 19 been be VBN cord-310304-f28tjmi8 205 20 shown show VBN cord-310304-f28tjmi8 205 21 to to TO cord-310304-f28tjmi8 205 22 have have VB cord-310304-f28tjmi8 205 23 less less JJR cord-310304-f28tjmi8 205 24 control control NN cord-310304-f28tjmi8 205 25 of of IN cord-310304-f28tjmi8 205 26 the the DT cord-310304-f28tjmi8 205 27 disease disease NN cord-310304-f28tjmi8 205 28 when when WRB cord-310304-f28tjmi8 205 29 compared compare VBN cord-310304-f28tjmi8 205 30 with with IN cord-310304-f28tjmi8 205 31 NHWs nhws NN cord-310304-f28tjmi8 205 32 [ [ -LRB- cord-310304-f28tjmi8 205 33 86 86 CD cord-310304-f28tjmi8 205 34 ] ] -RRB- cord-310304-f28tjmi8 205 35 [ [ -LRB- cord-310304-f28tjmi8 205 36 87 87 CD cord-310304-f28tjmi8 205 37 ] ] -RRB- cord-310304-f28tjmi8 205 38 [ [ -LRB- cord-310304-f28tjmi8 205 39 88 88 CD cord-310304-f28tjmi8 205 40 ] ] -RRB- cord-310304-f28tjmi8 205 41 [ [ -LRB- cord-310304-f28tjmi8 205 42 89 89 CD cord-310304-f28tjmi8 205 43 ] ] -RRB- cord-310304-f28tjmi8 205 44 . . . cord-310304-f28tjmi8 206 1 Pharmacotherapy pharmacotherapy NN cord-310304-f28tjmi8 206 2 in in IN cord-310304-f28tjmi8 206 3 the the DT cord-310304-f28tjmi8 206 4 form form NN cord-310304-f28tjmi8 206 5 of of IN cord-310304-f28tjmi8 206 6 thiazide thiazide NN cord-310304-f28tjmi8 206 7 - - HYPH cord-310304-f28tjmi8 206 8 type type NN cord-310304-f28tjmi8 206 9 diuretics diuretic NNS cord-310304-f28tjmi8 206 10 , , , cord-310304-f28tjmi8 206 11 calcium calcium NN cord-310304-f28tjmi8 206 12 channel channel NN cord-310304-f28tjmi8 206 13 blockers blocker NNS cord-310304-f28tjmi8 206 14 , , , cord-310304-f28tjmi8 206 15 ACEIs acei NNS cord-310304-f28tjmi8 206 16 or or CC cord-310304-f28tjmi8 206 17 Angiotensin Angiotensin NNP cord-310304-f28tjmi8 206 18 II II NNP cord-310304-f28tjmi8 206 19 receptor receptor NN cord-310304-f28tjmi8 206 20 blockers blocker NNS cord-310304-f28tjmi8 206 21 ( ( -LRB- cord-310304-f28tjmi8 206 22 ARBs arb NNS cord-310304-f28tjmi8 206 23 ) ) -RRB- cord-310304-f28tjmi8 206 24 , , , cord-310304-f28tjmi8 206 25 and and CC cord-310304-f28tjmi8 206 26 lifestyle lifestyle NN cord-310304-f28tjmi8 206 27 changes change NNS cord-310304-f28tjmi8 206 28 are be VBP cord-310304-f28tjmi8 206 29 essential essential JJ cord-310304-f28tjmi8 206 30 for for IN cord-310304-f28tjmi8 206 31 hypertension hypertension NN cord-310304-f28tjmi8 206 32 control control NN cord-310304-f28tjmi8 206 33 [ [ -LRB- cord-310304-f28tjmi8 206 34 61 61 CD cord-310304-f28tjmi8 206 35 ] ] -RRB- cord-310304-f28tjmi8 206 36 . . . cord-310304-f28tjmi8 207 1 Medication medication NN cord-310304-f28tjmi8 207 2 adherence adherence NN cord-310304-f28tjmi8 207 3 plays play VBZ cord-310304-f28tjmi8 207 4 a a DT cord-310304-f28tjmi8 207 5 critical critical JJ cord-310304-f28tjmi8 207 6 role role NN cord-310304-f28tjmi8 207 7 in in IN cord-310304-f28tjmi8 207 8 the the DT cord-310304-f28tjmi8 207 9 long long JJ cord-310304-f28tjmi8 207 10 - - HYPH cord-310304-f28tjmi8 207 11 term term NN cord-310304-f28tjmi8 207 12 management management NN cord-310304-f28tjmi8 207 13 of of IN cord-310304-f28tjmi8 207 14 hypertension hypertension NN cord-310304-f28tjmi8 207 15 , , , cord-310304-f28tjmi8 207 16 especially especially RB cord-310304-f28tjmi8 207 17 in in IN cord-310304-f28tjmi8 207 18 minority minority NN cord-310304-f28tjmi8 207 19 communities community NNS cord-310304-f28tjmi8 207 20 , , , cord-310304-f28tjmi8 207 21 and and CC cord-310304-f28tjmi8 207 22 is be VBZ cord-310304-f28tjmi8 207 23 directly directly RB cord-310304-f28tjmi8 207 24 related relate VBN cord-310304-f28tjmi8 207 25 to to IN cord-310304-f28tjmi8 207 26 racial racial JJ cord-310304-f28tjmi8 207 27 and and CC cord-310304-f28tjmi8 207 28 ethnic ethnic JJ cord-310304-f28tjmi8 207 29 disparities disparity NNS cord-310304-f28tjmi8 207 30 in in IN cord-310304-f28tjmi8 207 31 CVD CVD NNP cord-310304-f28tjmi8 207 32 , , , cord-310304-f28tjmi8 207 33 stroke stroke NN cord-310304-f28tjmi8 207 34 , , , cord-310304-f28tjmi8 207 35 and and CC cord-310304-f28tjmi8 207 36 chronic chronic JJ cord-310304-f28tjmi8 207 37 kidney kidney NN cord-310304-f28tjmi8 207 38 disease disease NN cord-310304-f28tjmi8 207 39 ( ( -LRB- cord-310304-f28tjmi8 207 40 CKD CKD NNP cord-310304-f28tjmi8 207 41 ) ) -RRB- cord-310304-f28tjmi8 207 42 . . . cord-310304-f28tjmi8 208 1 Ferdinand Ferdinand NNP cord-310304-f28tjmi8 208 2 et et NNP cord-310304-f28tjmi8 208 3 al al NNP cord-310304-f28tjmi8 208 4 . . . cord-310304-f28tjmi8 209 1 report report VB cord-310304-f28tjmi8 209 2 that that IN cord-310304-f28tjmi8 209 3 strategies strategy NNS cord-310304-f28tjmi8 209 4 such such JJ cord-310304-f28tjmi8 209 5 as as IN cord-310304-f28tjmi8 209 6 direct direct JJ cord-310304-f28tjmi8 209 7 patient patient NN cord-310304-f28tjmi8 209 8 engagement engagement NN cord-310304-f28tjmi8 209 9 , , , cord-310304-f28tjmi8 209 10 consumer consumer NN cord-310304-f28tjmi8 209 11 - - HYPH cord-310304-f28tjmi8 209 12 directed direct VBN cord-310304-f28tjmi8 209 13 health health NN cord-310304-f28tjmi8 209 14 care care NN cord-310304-f28tjmi8 209 15 , , , cord-310304-f28tjmi8 209 16 utilization utilization NN cord-310304-f28tjmi8 209 17 of of IN cord-310304-f28tjmi8 209 18 patient patient JJ cord-310304-f28tjmi8 209 19 portals portal NNS cord-310304-f28tjmi8 209 20 , , , cord-310304-f28tjmi8 209 21 smart smart JJ cord-310304-f28tjmi8 209 22 apps app NNS cord-310304-f28tjmi8 209 23 and and CC cord-310304-f28tjmi8 209 24 text text NN cord-310304-f28tjmi8 209 25 messages message NNS cord-310304-f28tjmi8 209 26 , , , cord-310304-f28tjmi8 209 27 digital digital JJ cord-310304-f28tjmi8 209 28 pillboxes pillbox NNS cord-310304-f28tjmi8 209 29 , , , cord-310304-f28tjmi8 209 30 pharmacist pharmacist NN cord-310304-f28tjmi8 209 31 - - HYPH cord-310304-f28tjmi8 209 32 led lead VBN cord-310304-f28tjmi8 209 33 engagement engagement NN cord-310304-f28tjmi8 209 34 , , , cord-310304-f28tjmi8 209 35 and and CC cord-310304-f28tjmi8 209 36 cognitive cognitive NN cord-310304-f28tjmi8 209 37 - - HYPH cord-310304-f28tjmi8 209 38 based base VBN cord-310304-f28tjmi8 209 39 behavior behavior NN cord-310304-f28tjmi8 209 40 , , , cord-310304-f28tjmi8 209 41 could could MD cord-310304-f28tjmi8 209 42 be be VB cord-310304-f28tjmi8 209 43 important important JJ cord-310304-f28tjmi8 209 44 for for IN cord-310304-f28tjmi8 209 45 improving improve VBG cord-310304-f28tjmi8 209 46 medical medical JJ cord-310304-f28tjmi8 209 47 adherence adherence NN cord-310304-f28tjmi8 209 48 and and CC cord-310304-f28tjmi8 209 49 reducing reduce VBG cord-310304-f28tjmi8 209 50 disparities disparity NNS cord-310304-f28tjmi8 209 51 in in IN cord-310304-f28tjmi8 209 52 hypertension hypertension NN cord-310304-f28tjmi8 209 53 and and CC cord-310304-f28tjmi8 209 54 its -PRON- PRP$ cord-310304-f28tjmi8 209 55 related related JJ cord-310304-f28tjmi8 209 56 complications complication NNS cord-310304-f28tjmi8 209 57 [ [ -LRB- cord-310304-f28tjmi8 209 58 90 90 CD cord-310304-f28tjmi8 209 59 ] ] -RRB- cord-310304-f28tjmi8 209 60 . . . cord-310304-f28tjmi8 210 1 The the DT cord-310304-f28tjmi8 210 2 Centers Centers NNPS cord-310304-f28tjmi8 210 3 for for IN cord-310304-f28tjmi8 210 4 Disease Disease NNP cord-310304-f28tjmi8 210 5 Control Control NNP cord-310304-f28tjmi8 210 6 and and CC cord-310304-f28tjmi8 210 7 Prevention Prevention NNP cord-310304-f28tjmi8 210 8 ( ( -LRB- cord-310304-f28tjmi8 210 9 CDC CDC NNP cord-310304-f28tjmi8 210 10 ) ) -RRB- cord-310304-f28tjmi8 210 11 reports report VBZ cord-310304-f28tjmi8 210 12 that that DT cord-310304-f28tjmi8 211 1 75 75 CD cord-310304-f28tjmi8 211 2 % % NN cord-310304-f28tjmi8 211 3 of of IN cord-310304-f28tjmi8 211 4 individuals individual NNS cord-310304-f28tjmi8 211 5 who who WP cord-310304-f28tjmi8 211 6 died die VBD cord-310304-f28tjmi8 211 7 of of IN cord-310304-f28tjmi8 211 8 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 211 9 disease disease NN cord-310304-f28tjmi8 211 10 were be VBD cord-310304-f28tjmi8 211 11 older old JJR cord-310304-f28tjmi8 211 12 than than IN cord-310304-f28tjmi8 211 13 65 65 CD cord-310304-f28tjmi8 211 14 years year NNS cord-310304-f28tjmi8 211 15 of of IN cord-310304-f28tjmi8 211 16 age age NN cord-310304-f28tjmi8 211 17 . . . cord-310304-f28tjmi8 212 1 Age age NN cord-310304-f28tjmi8 212 2 - - HYPH cord-310304-f28tjmi8 212 3 related relate VBN cord-310304-f28tjmi8 212 4 increase increase NN cord-310304-f28tjmi8 212 5 in in IN cord-310304-f28tjmi8 212 6 systolic systolic JJ cord-310304-f28tjmi8 212 7 blood blood NN cord-310304-f28tjmi8 212 8 pressure pressure NN cord-310304-f28tjmi8 212 9 suggests suggest VBZ cord-310304-f28tjmi8 212 10 that that IN cord-310304-f28tjmi8 212 11 90 90 CD cord-310304-f28tjmi8 212 12 % % NN cord-310304-f28tjmi8 212 13 of of IN cord-310304-f28tjmi8 212 14 adults adult NNS cord-310304-f28tjmi8 212 15 in in IN cord-310304-f28tjmi8 212 16 the the DT cord-310304-f28tjmi8 212 17 US US NNP cord-310304-f28tjmi8 212 18 will will MD cord-310304-f28tjmi8 212 19 develop develop VB cord-310304-f28tjmi8 212 20 hypertension hypertension NN cord-310304-f28tjmi8 212 21 in in IN cord-310304-f28tjmi8 212 22 their -PRON- PRP$ cord-310304-f28tjmi8 212 23 lifetime lifetime NN cord-310304-f28tjmi8 212 24 . . . cord-310304-f28tjmi8 213 1 This this DT cord-310304-f28tjmi8 213 2 age age NN cord-310304-f28tjmi8 213 3 - - HYPH cord-310304-f28tjmi8 213 4 related relate VBN cord-310304-f28tjmi8 213 5 increase increase NN cord-310304-f28tjmi8 213 6 in in IN cord-310304-f28tjmi8 213 7 blood blood NN cord-310304-f28tjmi8 213 8 pressure pressure NN cord-310304-f28tjmi8 213 9 likely likely RB cord-310304-f28tjmi8 213 10 contributes contribute VBZ cord-310304-f28tjmi8 213 11 to to IN cord-310304-f28tjmi8 213 12 increased increase VBN cord-310304-f28tjmi8 213 13 age age NN cord-310304-f28tjmi8 213 14 - - HYPH cord-310304-f28tjmi8 213 15 related relate VBN cord-310304-f28tjmi8 213 16 mortality mortality NN cord-310304-f28tjmi8 213 17 among among IN cord-310304-f28tjmi8 213 18 the the DT cord-310304-f28tjmi8 213 19 elderly elderly JJ cord-310304-f28tjmi8 213 20 with with IN cord-310304-f28tjmi8 213 21 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 213 22 . . . cord-310304-f28tjmi8 214 1 It -PRON- PRP cord-310304-f28tjmi8 214 2 has have VBZ cord-310304-f28tjmi8 214 3 been be VBN cord-310304-f28tjmi8 214 4 proposed propose VBN cord-310304-f28tjmi8 214 5 that that IN cord-310304-f28tjmi8 214 6 CVD CVD NNP cord-310304-f28tjmi8 214 7 is be VBZ cord-310304-f28tjmi8 214 8 more more RBR cord-310304-f28tjmi8 214 9 prevalent prevalent JJ cord-310304-f28tjmi8 214 10 in in IN cord-310304-f28tjmi8 214 11 older old JJR cord-310304-f28tjmi8 214 12 patients patient NNS cord-310304-f28tjmi8 214 13 , , , cord-310304-f28tjmi8 214 14 as as IN cord-310304-f28tjmi8 214 15 these these DT cord-310304-f28tjmi8 214 16 patients patient NNS cord-310304-f28tjmi8 214 17 are be VBP cord-310304-f28tjmi8 214 18 more more RBR cord-310304-f28tjmi8 214 19 likely likely JJ cord-310304-f28tjmi8 214 20 to to TO cord-310304-f28tjmi8 214 21 have have VB cord-310304-f28tjmi8 214 22 impaired impair VBN cord-310304-f28tjmi8 214 23 immune immune JJ cord-310304-f28tjmi8 214 24 systems system NNS cord-310304-f28tjmi8 214 25 that that WDT cord-310304-f28tjmi8 214 26 loses lose VBZ cord-310304-f28tjmi8 214 27 the the DT cord-310304-f28tjmi8 214 28 ability ability NN cord-310304-f28tjmi8 214 29 to to TO cord-310304-f28tjmi8 214 30 responds respond VBZ cord-310304-f28tjmi8 214 31 effectively effectively RB cord-310304-f28tjmi8 214 32 to to IN cord-310304-f28tjmi8 214 33 infections infection NNS cord-310304-f28tjmi8 214 34 and and CC cord-310304-f28tjmi8 214 35 the the DT cord-310304-f28tjmi8 214 36 reduced reduced JJ cord-310304-f28tjmi8 214 37 levels level NNS cord-310304-f28tjmi8 214 38 of of IN cord-310304-f28tjmi8 214 39 ACE2 ACE2 NNP cord-310304-f28tjmi8 214 40 observed observe VBD cord-310304-f28tjmi8 214 41 among among IN cord-310304-f28tjmi8 214 42 the the DT cord-310304-f28tjmi8 214 43 elderly elderly JJ cord-310304-f28tjmi8 214 44 may may MD cord-310304-f28tjmi8 214 45 predispose predispose VB cord-310304-f28tjmi8 214 46 older old JJR cord-310304-f28tjmi8 214 47 patients patient NNS cord-310304-f28tjmi8 214 48 to to IN cord-310304-f28tjmi8 214 49 more more RBR cord-310304-f28tjmi8 214 50 severe severe JJ cord-310304-f28tjmi8 214 51 complications complication NNS cord-310304-f28tjmi8 214 52 of of IN cord-310304-f28tjmi8 214 53 COVID-19 covid-19 NN cord-310304-f28tjmi8 214 54 due due IN cord-310304-f28tjmi8 214 55 to to IN cord-310304-f28tjmi8 214 56 loss loss NN cord-310304-f28tjmi8 214 57 of of IN cord-310304-f28tjmi8 214 58 the the DT cord-310304-f28tjmi8 214 59 protective protective JJ cord-310304-f28tjmi8 214 60 effects effect NNS cord-310304-f28tjmi8 214 61 of of IN cord-310304-f28tjmi8 214 62 ACE2 ACE2 NNP cord-310304-f28tjmi8 214 63 to to TO cord-310304-f28tjmi8 214 64 regulate regulate VB cord-310304-f28tjmi8 214 65 and and CC cord-310304-f28tjmi8 214 66 control control VB cord-310304-f28tjmi8 214 67 inflammation inflammation NN cord-310304-f28tjmi8 214 68 . . . cord-310304-f28tjmi8 215 1 Therefore therefore RB cord-310304-f28tjmi8 215 2 , , , cord-310304-f28tjmi8 215 3 patients patient NNS cord-310304-f28tjmi8 215 4 with with IN cord-310304-f28tjmi8 215 5 CVD CVD NNP cord-310304-f28tjmi8 215 6 should should MD cord-310304-f28tjmi8 215 7 be be VB cord-310304-f28tjmi8 215 8 subjected subject VBN cord-310304-f28tjmi8 215 9 first first RB cord-310304-f28tjmi8 215 10 to to IN cord-310304-f28tjmi8 215 11 preventive preventive JJ cord-310304-f28tjmi8 215 12 measures measure NNS cord-310304-f28tjmi8 215 13 , , , cord-310304-f28tjmi8 215 14 such such JJ cord-310304-f28tjmi8 215 15 as as IN cord-310304-f28tjmi8 215 16 monitoring monitor VBG cord-310304-f28tjmi8 215 17 for for IN cord-310304-f28tjmi8 215 18 elevated elevated JJ cord-310304-f28tjmi8 215 19 cardiac cardiac JJ cord-310304-f28tjmi8 215 20 biomarkers biomarker NNS cord-310304-f28tjmi8 215 21 , , , cord-310304-f28tjmi8 215 22 and and CC cord-310304-f28tjmi8 215 23 if if IN cord-310304-f28tjmi8 215 24 necessary necessary JJ cord-310304-f28tjmi8 215 25 , , , cord-310304-f28tjmi8 215 26 should should MD cord-310304-f28tjmi8 215 27 be be VB cord-310304-f28tjmi8 215 28 isolated isolate VBN cord-310304-f28tjmi8 215 29 from from IN cord-310304-f28tjmi8 215 30 other other JJ cord-310304-f28tjmi8 215 31 patient patient JJ cord-310304-f28tjmi8 215 32 populations population NNS cord-310304-f28tjmi8 215 33 that that WDT cord-310304-f28tjmi8 215 34 would would MD cord-310304-f28tjmi8 215 35 place place VB cord-310304-f28tjmi8 215 36 them -PRON- PRP cord-310304-f28tjmi8 215 37 at at IN cord-310304-f28tjmi8 215 38 higher high JJR cord-310304-f28tjmi8 215 39 risk risk NN cord-310304-f28tjmi8 215 40 . . . cord-310304-f28tjmi8 216 1 In in IN cord-310304-f28tjmi8 216 2 addition addition NN cord-310304-f28tjmi8 216 3 , , , cord-310304-f28tjmi8 216 4 a a DT cord-310304-f28tjmi8 216 5 report report NN cord-310304-f28tjmi8 216 6 from from IN cord-310304-f28tjmi8 216 7 the the DT cord-310304-f28tjmi8 216 8 National National NNP cord-310304-f28tjmi8 216 9 Health Health NNP cord-310304-f28tjmi8 216 10 Commission Commission NNP cord-310304-f28tjmi8 216 11 of of IN cord-310304-f28tjmi8 216 12 China China NNP cord-310304-f28tjmi8 216 13 revealed reveal VBD cord-310304-f28tjmi8 216 14 that that IN cord-310304-f28tjmi8 216 15 almost almost RB cord-310304-f28tjmi8 216 16 12 12 CD cord-310304-f28tjmi8 216 17 % % NN cord-310304-f28tjmi8 216 18 of of IN cord-310304-f28tjmi8 216 19 COVID-19 covid-19 JJ cord-310304-f28tjmi8 216 20 patients patient NNS cord-310304-f28tjmi8 216 21 without without IN cord-310304-f28tjmi8 216 22 known know VBN cord-310304-f28tjmi8 216 23 CVD CVD NNP cord-310304-f28tjmi8 216 24 risk risk NN cord-310304-f28tjmi8 216 25 had have VBD cord-310304-f28tjmi8 216 26 elevated elevate VBN cord-310304-f28tjmi8 216 27 troponin troponin JJ cord-310304-f28tjmi8 216 28 levels level NNS cord-310304-f28tjmi8 216 29 or or CC cord-310304-f28tjmi8 216 30 cardiac cardiac JJ cord-310304-f28tjmi8 216 31 arrest arrest NN cord-310304-f28tjmi8 216 32 during during IN cord-310304-f28tjmi8 216 33 hospitalization hospitalization NN cord-310304-f28tjmi8 216 34 [ [ -LRB- cord-310304-f28tjmi8 216 35 91 91 CD cord-310304-f28tjmi8 216 36 ] ] -RRB- cord-310304-f28tjmi8 216 37 . . . cord-310304-f28tjmi8 217 1 This this DT cord-310304-f28tjmi8 217 2 would would MD cord-310304-f28tjmi8 217 3 suggest suggest VB cord-310304-f28tjmi8 217 4 that that IN cord-310304-f28tjmi8 217 5 SARS SARS NNP cord-310304-f28tjmi8 217 6 - - HYPH cord-310304-f28tjmi8 217 7 CoV-2-mediated cov-2-mediate VBN cord-310304-f28tjmi8 217 8 infection infection NN cord-310304-f28tjmi8 217 9 may may MD cord-310304-f28tjmi8 217 10 lead lead VB cord-310304-f28tjmi8 217 11 directly directly RB cord-310304-f28tjmi8 217 12 to to IN cord-310304-f28tjmi8 217 13 myocardial myocardial JJ cord-310304-f28tjmi8 217 14 dysfunction dysfunction NN cord-310304-f28tjmi8 217 15 . . . cord-310304-f28tjmi8 218 1 Potential potential JJ cord-310304-f28tjmi8 218 2 benefit benefit NN cord-310304-f28tjmi8 218 3 or or CC cord-310304-f28tjmi8 218 4 harm harm NN cord-310304-f28tjmi8 218 5 from from IN cord-310304-f28tjmi8 218 6 ACEIs acei NNS cord-310304-f28tjmi8 218 7 and and CC cord-310304-f28tjmi8 218 8 ARBs arb NNS cord-310304-f28tjmi8 218 9 , , , cord-310304-f28tjmi8 218 10 commonly commonly RB cord-310304-f28tjmi8 218 11 prescribed prescribe VBN cord-310304-f28tjmi8 218 12 for for IN cord-310304-f28tjmi8 218 13 cardiovascular cardiovascular JJ cord-310304-f28tjmi8 218 14 disorders disorder NNS cord-310304-f28tjmi8 218 15 , , , cord-310304-f28tjmi8 218 16 is be VBZ cord-310304-f28tjmi8 218 17 still still RB cord-310304-f28tjmi8 218 18 under under IN cord-310304-f28tjmi8 218 19 investigation investigation NN cord-310304-f28tjmi8 218 20 due due JJ cord-310304-f28tjmi8 218 21 to to IN cord-310304-f28tjmi8 218 22 lack lack NN cord-310304-f28tjmi8 218 23 of of IN cord-310304-f28tjmi8 218 24 available available JJ cord-310304-f28tjmi8 218 25 evidence evidence NN cord-310304-f28tjmi8 218 26 . . . cord-310304-f28tjmi8 219 1 Individuals individual NNS cord-310304-f28tjmi8 219 2 with with IN cord-310304-f28tjmi8 219 3 COPD COPD NNP cord-310304-f28tjmi8 219 4 and and CC cord-310304-f28tjmi8 219 5 confirmed confirm VBD cord-310304-f28tjmi8 219 6 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 219 7 are be VBP cord-310304-f28tjmi8 219 8 at at IN cord-310304-f28tjmi8 219 9 greater great JJR cord-310304-f28tjmi8 219 10 risk risk NN cord-310304-f28tjmi8 219 11 of of IN cord-310304-f28tjmi8 219 12 severe severe JJ cord-310304-f28tjmi8 219 13 complications complication NNS cord-310304-f28tjmi8 219 14 and and CC cord-310304-f28tjmi8 219 15 death death NN cord-310304-f28tjmi8 219 16 than than IN cord-310304-f28tjmi8 219 17 individuals individual NNS cord-310304-f28tjmi8 219 18 without without IN cord-310304-f28tjmi8 219 19 COPD COPD NNP cord-310304-f28tjmi8 219 20 . . . cord-310304-f28tjmi8 220 1 Optimal optimal JJ cord-310304-f28tjmi8 220 2 testing testing NN cord-310304-f28tjmi8 220 3 and and CC cord-310304-f28tjmi8 220 4 diagnostics diagnostic NNS cord-310304-f28tjmi8 220 5 , , , cord-310304-f28tjmi8 220 6 as as RB cord-310304-f28tjmi8 220 7 well well RB cord-310304-f28tjmi8 220 8 as as IN cord-310304-f28tjmi8 220 9 management management NN cord-310304-f28tjmi8 220 10 of of IN cord-310304-f28tjmi8 220 11 individuals individual NNS cord-310304-f28tjmi8 220 12 with with IN cord-310304-f28tjmi8 220 13 COPD COPD NNP cord-310304-f28tjmi8 220 14 in in IN cord-310304-f28tjmi8 220 15 underserved underserved JJ cord-310304-f28tjmi8 220 16 communities community NNS cord-310304-f28tjmi8 220 17 , , , cord-310304-f28tjmi8 220 18 should should MD cord-310304-f28tjmi8 220 19 be be VB cord-310304-f28tjmi8 220 20 made make VBN cord-310304-f28tjmi8 220 21 available available JJ cord-310304-f28tjmi8 220 22 for for IN cord-310304-f28tjmi8 220 23 early early JJ cord-310304-f28tjmi8 220 24 intervention intervention NN cord-310304-f28tjmi8 220 25 and and CC cord-310304-f28tjmi8 220 26 treatment treatment NN cord-310304-f28tjmi8 220 27 . . . cord-310304-f28tjmi8 221 1 These these DT cord-310304-f28tjmi8 221 2 individuals individual NNS cord-310304-f28tjmi8 221 3 should should MD cord-310304-f28tjmi8 221 4 be be VB cord-310304-f28tjmi8 221 5 screened screen VBN cord-310304-f28tjmi8 221 6 for for IN cord-310304-f28tjmi8 221 7 other other JJ cord-310304-f28tjmi8 221 8 comorbidities comorbiditie NNS cord-310304-f28tjmi8 221 9 that that WDT cord-310304-f28tjmi8 221 10 are be VBP cord-310304-f28tjmi8 221 11 associated associate VBN cord-310304-f28tjmi8 221 12 with with IN cord-310304-f28tjmi8 221 13 the the DT cord-310304-f28tjmi8 221 14 development development NN cord-310304-f28tjmi8 221 15 of of IN cord-310304-f28tjmi8 221 16 COPD COPD NNP cord-310304-f28tjmi8 221 17 , , , cord-310304-f28tjmi8 221 18 such such JJ cord-310304-f28tjmi8 221 19 as as IN cord-310304-f28tjmi8 221 20 asthma asthma NN cord-310304-f28tjmi8 221 21 , , , cord-310304-f28tjmi8 221 22 lung lung NN cord-310304-f28tjmi8 221 23 infections infection NNS cord-310304-f28tjmi8 221 24 , , , cord-310304-f28tjmi8 221 25 and and CC cord-310304-f28tjmi8 221 26 other other JJ cord-310304-f28tjmi8 221 27 related related JJ cord-310304-f28tjmi8 221 28 respiratory respiratory JJ cord-310304-f28tjmi8 221 29 diseases disease NNS cord-310304-f28tjmi8 221 30 . . . cord-310304-f28tjmi8 222 1 Affordability affordability NN cord-310304-f28tjmi8 222 2 and and CC cord-310304-f28tjmi8 222 3 access access NN cord-310304-f28tjmi8 222 4 to to IN cord-310304-f28tjmi8 222 5 treatments treatment NNS cord-310304-f28tjmi8 222 6 and and CC cord-310304-f28tjmi8 222 7 palliative palliative JJ cord-310304-f28tjmi8 222 8 care care NN cord-310304-f28tjmi8 222 9 should should MD cord-310304-f28tjmi8 222 10 be be VB cord-310304-f28tjmi8 222 11 made make VBN cord-310304-f28tjmi8 222 12 available available JJ cord-310304-f28tjmi8 222 13 to to IN cord-310304-f28tjmi8 222 14 low low JJ cord-310304-f28tjmi8 222 15 - - HYPH cord-310304-f28tjmi8 222 16 income income NN cord-310304-f28tjmi8 222 17 COPD COPD NNP cord-310304-f28tjmi8 222 18 patients patient NNS cord-310304-f28tjmi8 222 19 . . . cord-310304-f28tjmi8 223 1 Furthermore furthermore RB cord-310304-f28tjmi8 223 2 , , , cord-310304-f28tjmi8 223 3 COPD COPD NNP cord-310304-f28tjmi8 223 4 patients patient NNS cord-310304-f28tjmi8 223 5 should should MD cord-310304-f28tjmi8 223 6 be be VB cord-310304-f28tjmi8 223 7 allowed allow VBN cord-310304-f28tjmi8 223 8 access access NN cord-310304-f28tjmi8 223 9 to to IN cord-310304-f28tjmi8 223 10 optimal optimal JJ cord-310304-f28tjmi8 223 11 life life NN cord-310304-f28tjmi8 223 12 - - HYPH cord-310304-f28tjmi8 223 13 extending extend VBG cord-310304-f28tjmi8 223 14 treatments treatment NNS cord-310304-f28tjmi8 223 15 for for IN cord-310304-f28tjmi8 223 16 their -PRON- PRP$ cord-310304-f28tjmi8 223 17 disease disease NN cord-310304-f28tjmi8 223 18 , , , cord-310304-f28tjmi8 223 19 including include VBG cord-310304-f28tjmi8 223 20 medical medical JJ cord-310304-f28tjmi8 223 21 specialists specialist NNS cord-310304-f28tjmi8 223 22 , , , cord-310304-f28tjmi8 223 23 more more JJR cord-310304-f28tjmi8 223 24 effective effective JJ cord-310304-f28tjmi8 223 25 drug drug NN cord-310304-f28tjmi8 223 26 treatments treatment NNS cord-310304-f28tjmi8 223 27 , , , cord-310304-f28tjmi8 223 28 smoking smoke VBG cord-310304-f28tjmi8 223 29 cessation cessation NN cord-310304-f28tjmi8 223 30 counseling counseling NN cord-310304-f28tjmi8 223 31 , , , cord-310304-f28tjmi8 223 32 supplemental supplemental JJ cord-310304-f28tjmi8 223 33 oxygen oxygen NN cord-310304-f28tjmi8 223 34 , , , cord-310304-f28tjmi8 223 35 and and CC cord-310304-f28tjmi8 223 36 non non JJ cord-310304-f28tjmi8 223 37 - - JJ cord-310304-f28tjmi8 223 38 invasive invasive JJ cord-310304-f28tjmi8 223 39 ventilation ventilation NN cord-310304-f28tjmi8 223 40 that that WDT cord-310304-f28tjmi8 223 41 often often RB cord-310304-f28tjmi8 223 42 are be VBP cord-310304-f28tjmi8 223 43 unaffordable unaffordable JJ cord-310304-f28tjmi8 223 44 for for IN cord-310304-f28tjmi8 223 45 these these DT cord-310304-f28tjmi8 223 46 vulnerable vulnerable JJ cord-310304-f28tjmi8 223 47 populations population NNS cord-310304-f28tjmi8 223 48 [ [ -LRB- cord-310304-f28tjmi8 223 49 92 92 CD cord-310304-f28tjmi8 223 50 ] ] -RRB- cord-310304-f28tjmi8 223 51 . . . cord-310304-f28tjmi8 224 1 Having have VBG cord-310304-f28tjmi8 224 2 COPD COPD NNP cord-310304-f28tjmi8 224 3 and and CC cord-310304-f28tjmi8 224 4 being be VBG cord-310304-f28tjmi8 224 5 a a DT cord-310304-f28tjmi8 224 6 current current JJ cord-310304-f28tjmi8 224 7 smoker smoker NN cord-310304-f28tjmi8 224 8 may may MD cord-310304-f28tjmi8 224 9 greatly greatly RB cord-310304-f28tjmi8 224 10 increase increase VB cord-310304-f28tjmi8 224 11 the the DT cord-310304-f28tjmi8 224 12 risk risk NN cord-310304-f28tjmi8 224 13 of of IN cord-310304-f28tjmi8 224 14 complications complication NNS cord-310304-f28tjmi8 224 15 mortality mortality NN cord-310304-f28tjmi8 224 16 from from IN cord-310304-f28tjmi8 224 17 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 224 18 . . . cord-310304-f28tjmi8 225 1 Interventions intervention NNS cord-310304-f28tjmi8 225 2 in in IN cord-310304-f28tjmi8 225 3 COPD COPD NNP cord-310304-f28tjmi8 225 4 patients patient NNS cord-310304-f28tjmi8 225 5 who who WP cord-310304-f28tjmi8 225 6 smoke smoke VBP cord-310304-f28tjmi8 225 7 should should MD cord-310304-f28tjmi8 225 8 include include VB cord-310304-f28tjmi8 225 9 smoking smoking NN cord-310304-f28tjmi8 225 10 cessation cessation NN cord-310304-f28tjmi8 225 11 , , , cord-310304-f28tjmi8 225 12 as as IN cord-310304-f28tjmi8 225 13 it -PRON- PRP cord-310304-f28tjmi8 225 14 has have VBZ cord-310304-f28tjmi8 225 15 been be VBN cord-310304-f28tjmi8 225 16 demonstrated demonstrate VBN cord-310304-f28tjmi8 225 17 to to TO cord-310304-f28tjmi8 225 18 improve improve VB cord-310304-f28tjmi8 225 19 pulmonary pulmonary JJ cord-310304-f28tjmi8 225 20 function function NN cord-310304-f28tjmi8 225 21 in in IN cord-310304-f28tjmi8 225 22 younger young JJR cord-310304-f28tjmi8 225 23 smokers smoker NNS cord-310304-f28tjmi8 225 24 compared compare VBN cord-310304-f28tjmi8 225 25 with with IN cord-310304-f28tjmi8 225 26 older old JJR cord-310304-f28tjmi8 225 27 smokers smoker NNS cord-310304-f28tjmi8 225 28 who who WP cord-310304-f28tjmi8 225 29 have have VBP cord-310304-f28tjmi8 225 30 sustained sustain VBN cord-310304-f28tjmi8 225 31 cumulative cumulative JJ cord-310304-f28tjmi8 225 32 lung lung NN cord-310304-f28tjmi8 225 33 damage damage NN cord-310304-f28tjmi8 225 34 over over IN cord-310304-f28tjmi8 225 35 time time NN cord-310304-f28tjmi8 225 36 [ [ -LRB- cord-310304-f28tjmi8 225 37 92 92 CD cord-310304-f28tjmi8 225 38 ] ] -RRB- cord-310304-f28tjmi8 225 39 . . . cord-310304-f28tjmi8 226 1 Essential essential JJ cord-310304-f28tjmi8 226 2 workers worker NNS cord-310304-f28tjmi8 226 3 , , , cord-310304-f28tjmi8 226 4 who who WP cord-310304-f28tjmi8 226 5 often often RB cord-310304-f28tjmi8 226 6 are be VBP cord-310304-f28tjmi8 226 7 from from IN cord-310304-f28tjmi8 226 8 minority minority NN cord-310304-f28tjmi8 226 9 communities community NNS cord-310304-f28tjmi8 226 10 and and CC cord-310304-f28tjmi8 226 11 face face VB cord-310304-f28tjmi8 226 12 occupational occupational JJ cord-310304-f28tjmi8 226 13 hazards hazard NNS cord-310304-f28tjmi8 226 14 , , , cord-310304-f28tjmi8 226 15 are be VBP cord-310304-f28tjmi8 226 16 at at IN cord-310304-f28tjmi8 226 17 greater great JJR cord-310304-f28tjmi8 226 18 risk risk NN cord-310304-f28tjmi8 226 19 for for IN cord-310304-f28tjmi8 226 20 developing develop VBG cord-310304-f28tjmi8 226 21 occupation occupation NN cord-310304-f28tjmi8 226 22 - - HYPH cord-310304-f28tjmi8 226 23 related relate VBN cord-310304-f28tjmi8 226 24 COPD COPD NNP cord-310304-f28tjmi8 226 25 . . . cord-310304-f28tjmi8 227 1 Understanding understand VBG cord-310304-f28tjmi8 227 2 clinical clinical JJ cord-310304-f28tjmi8 227 3 risk risk NN cord-310304-f28tjmi8 227 4 factors factor NNS cord-310304-f28tjmi8 227 5 and and CC cord-310304-f28tjmi8 227 6 their -PRON- PRP$ cord-310304-f28tjmi8 227 7 mechanisms mechanism NNS cord-310304-f28tjmi8 227 8 can can MD cord-310304-f28tjmi8 227 9 benefit benefit VB cord-310304-f28tjmi8 227 10 disparity disparity NN cord-310304-f28tjmi8 227 11 populations population NNS cord-310304-f28tjmi8 227 12 by by IN cord-310304-f28tjmi8 227 13 identifying identify VBG cord-310304-f28tjmi8 227 14 at at IN cord-310304-f28tjmi8 227 15 risk risk NN cord-310304-f28tjmi8 227 16 individuals individual NNS cord-310304-f28tjmi8 227 17 early early RB cord-310304-f28tjmi8 227 18 and and CC cord-310304-f28tjmi8 227 19 developing develop VBG cord-310304-f28tjmi8 227 20 early early JJ cord-310304-f28tjmi8 227 21 intervention intervention NN cord-310304-f28tjmi8 227 22 strategies strategy NNS cord-310304-f28tjmi8 227 23 that that WDT cord-310304-f28tjmi8 227 24 are be VBP cord-310304-f28tjmi8 227 25 designed design VBN cord-310304-f28tjmi8 227 26 to to TO cord-310304-f28tjmi8 227 27 manage manage VB cord-310304-f28tjmi8 227 28 these these DT cord-310304-f28tjmi8 227 29 risk risk NN cord-310304-f28tjmi8 227 30 factors factor NNS cord-310304-f28tjmi8 227 31 in in IN cord-310304-f28tjmi8 227 32 the the DT cord-310304-f28tjmi8 227 33 context context NN cord-310304-f28tjmi8 227 34 of of IN cord-310304-f28tjmi8 227 35 clinical clinical JJ cord-310304-f28tjmi8 227 36 trials trial NNS cord-310304-f28tjmi8 227 37 where where WRB cord-310304-f28tjmi8 227 38 access access NN cord-310304-f28tjmi8 227 39 to to IN cord-310304-f28tjmi8 227 40 care care NN cord-310304-f28tjmi8 227 41 and and CC cord-310304-f28tjmi8 227 42 drug drug NN cord-310304-f28tjmi8 227 43 compliance compliance NN cord-310304-f28tjmi8 227 44 can can MD cord-310304-f28tjmi8 227 45 be be VB cord-310304-f28tjmi8 227 46 controlled control VBN cord-310304-f28tjmi8 227 47 . . . cord-310304-f28tjmi8 228 1 The the DT cord-310304-f28tjmi8 228 2 benefits benefit NNS cord-310304-f28tjmi8 228 3 of of IN cord-310304-f28tjmi8 228 4 understanding understand VBG cord-310304-f28tjmi8 228 5 these these DT cord-310304-f28tjmi8 228 6 mechanisms mechanism NNS cord-310304-f28tjmi8 228 7 could could MD cord-310304-f28tjmi8 228 8 also also RB cord-310304-f28tjmi8 228 9 provide provide VB cord-310304-f28tjmi8 228 10 information information NN cord-310304-f28tjmi8 228 11 that that WDT cord-310304-f28tjmi8 228 12 contributes contribute VBZ cord-310304-f28tjmi8 228 13 to to IN cord-310304-f28tjmi8 228 14 innovative innovative JJ cord-310304-f28tjmi8 228 15 therapies therapy NNS cord-310304-f28tjmi8 228 16 that that WDT cord-310304-f28tjmi8 228 17 identify identify VBP cord-310304-f28tjmi8 228 18 selective selective JJ cord-310304-f28tjmi8 228 19 targets target NNS cord-310304-f28tjmi8 228 20 within within IN cord-310304-f28tjmi8 228 21 these these DT cord-310304-f28tjmi8 228 22 pathways pathway NNS cord-310304-f28tjmi8 228 23 among among IN cord-310304-f28tjmi8 228 24 disparity disparity NN cord-310304-f28tjmi8 228 25 populations population NNS cord-310304-f28tjmi8 228 26 based base VBN cord-310304-f28tjmi8 228 27 on on IN cord-310304-f28tjmi8 228 28 unique unique JJ cord-310304-f28tjmi8 228 29 genetic genetic JJ cord-310304-f28tjmi8 228 30 profiles profile NNS cord-310304-f28tjmi8 228 31 . . . cord-310304-f28tjmi8 229 1 Finally finally RB cord-310304-f28tjmi8 229 2 , , , cord-310304-f28tjmi8 229 3 an an DT cord-310304-f28tjmi8 229 4 understanding understanding NN cord-310304-f28tjmi8 229 5 of of IN cord-310304-f28tjmi8 229 6 these these DT cord-310304-f28tjmi8 229 7 mechanisms mechanism NNS cord-310304-f28tjmi8 229 8 could could MD cord-310304-f28tjmi8 229 9 lead lead VB cord-310304-f28tjmi8 229 10 to to IN cord-310304-f28tjmi8 229 11 changes change NNS cord-310304-f28tjmi8 229 12 among among IN cord-310304-f28tjmi8 229 13 health health NN cord-310304-f28tjmi8 229 14 providers provider NNS cord-310304-f28tjmi8 229 15 to to TO cord-310304-f28tjmi8 229 16 be be VB cord-310304-f28tjmi8 229 17 more more RBR cord-310304-f28tjmi8 229 18 aggressive aggressive JJ cord-310304-f28tjmi8 229 19 in in IN cord-310304-f28tjmi8 229 20 their -PRON- PRP$ cord-310304-f28tjmi8 229 21 care care NN cord-310304-f28tjmi8 229 22 for for IN cord-310304-f28tjmi8 229 23 these these DT cord-310304-f28tjmi8 229 24 patients patient NNS cord-310304-f28tjmi8 229 25 as as IN cord-310304-f28tjmi8 229 26 clinical clinical JJ cord-310304-f28tjmi8 229 27 trial trial NN cord-310304-f28tjmi8 229 28 data datum NNS cord-310304-f28tjmi8 229 29 become become VBP cord-310304-f28tjmi8 229 30 available available JJ cord-310304-f28tjmi8 229 31 , , , cord-310304-f28tjmi8 229 32 leading lead VBG cord-310304-f28tjmi8 229 33 changes change NNS cord-310304-f28tjmi8 229 34 in in IN cord-310304-f28tjmi8 229 35 health health NN cord-310304-f28tjmi8 229 36 policy policy NN cord-310304-f28tjmi8 229 37 for for IN cord-310304-f28tjmi8 229 38 underserved underserved JJ cord-310304-f28tjmi8 229 39 populations population NNS cord-310304-f28tjmi8 229 40 . . . cord-310304-f28tjmi8 230 1 Changes change NNS cord-310304-f28tjmi8 230 2 in in IN cord-310304-f28tjmi8 230 3 public public JJ cord-310304-f28tjmi8 230 4 policy policy NN cord-310304-f28tjmi8 230 5 are be VBP cord-310304-f28tjmi8 230 6 essential essential JJ cord-310304-f28tjmi8 230 7 to to TO cord-310304-f28tjmi8 230 8 combat combat VB cord-310304-f28tjmi8 230 9 the the DT cord-310304-f28tjmi8 230 10 long long RB cord-310304-f28tjmi8 230 11 - - HYPH cord-310304-f28tjmi8 230 12 standing stand VBG cord-310304-f28tjmi8 230 13 problems problem NNS cord-310304-f28tjmi8 230 14 associated associate VBN cord-310304-f28tjmi8 230 15 with with IN cord-310304-f28tjmi8 230 16 health health NN cord-310304-f28tjmi8 230 17 inequities inequity NNS cord-310304-f28tjmi8 230 18 in in IN cord-310304-f28tjmi8 230 19 our -PRON- PRP$ cord-310304-f28tjmi8 230 20 health health NN cord-310304-f28tjmi8 230 21 care care NN cord-310304-f28tjmi8 230 22 system system NN cord-310304-f28tjmi8 230 23 . . . cord-310304-f28tjmi8 231 1 These these DT cord-310304-f28tjmi8 231 2 inequalities inequality NNS cord-310304-f28tjmi8 231 3 are be VBP cord-310304-f28tjmi8 231 4 more more RBR cord-310304-f28tjmi8 231 5 pronounced pronounced JJ cord-310304-f28tjmi8 231 6 during during IN cord-310304-f28tjmi8 231 7 a a DT cord-310304-f28tjmi8 231 8 health health NN cord-310304-f28tjmi8 231 9 care care NN cord-310304-f28tjmi8 231 10 crisis crisis NN cord-310304-f28tjmi8 231 11 , , , cord-310304-f28tjmi8 231 12 such such JJ cord-310304-f28tjmi8 231 13 as as IN cord-310304-f28tjmi8 231 14 the the DT cord-310304-f28tjmi8 231 15 current current JJ cord-310304-f28tjmi8 231 16 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 231 17 pandemic pandemic NN cord-310304-f28tjmi8 231 18 . . . cord-310304-f28tjmi8 232 1 Addressing address VBG cord-310304-f28tjmi8 232 2 these these DT cord-310304-f28tjmi8 232 3 inequities inequity NNS cord-310304-f28tjmi8 232 4 would would MD cord-310304-f28tjmi8 232 5 require require VB cord-310304-f28tjmi8 232 6 a a DT cord-310304-f28tjmi8 232 7 government government NN cord-310304-f28tjmi8 232 8 - - HYPH cord-310304-f28tjmi8 232 9 appointed appoint VBN cord-310304-f28tjmi8 232 10 race race NN cord-310304-f28tjmi8 232 11 / / SYM cord-310304-f28tjmi8 232 12 inequity inequity NN cord-310304-f28tjmi8 232 13 task task NN cord-310304-f28tjmi8 232 14 force force NN cord-310304-f28tjmi8 232 15 that that WDT cord-310304-f28tjmi8 232 16 is be VBZ cord-310304-f28tjmi8 232 17 designed design VBN cord-310304-f28tjmi8 232 18 to to TO cord-310304-f28tjmi8 232 19 implement implement VB cord-310304-f28tjmi8 232 20 pre pre JJ cord-310304-f28tjmi8 232 21 - - JJ cord-310304-f28tjmi8 232 22 determined determined JJ cord-310304-f28tjmi8 232 23 standards standard NNS cord-310304-f28tjmi8 232 24 of of IN cord-310304-f28tjmi8 232 25 care care NN cord-310304-f28tjmi8 232 26 in in IN cord-310304-f28tjmi8 232 27 minority minority NN cord-310304-f28tjmi8 232 28 communities community NNS cord-310304-f28tjmi8 232 29 at at IN cord-310304-f28tjmi8 232 30 an an DT cord-310304-f28tjmi8 232 31 early early JJ cord-310304-f28tjmi8 232 32 stage stage NN cord-310304-f28tjmi8 232 33 in in IN cord-310304-f28tjmi8 232 34 a a DT cord-310304-f28tjmi8 232 35 medical medical JJ cord-310304-f28tjmi8 232 36 crisis crisis NN cord-310304-f28tjmi8 232 37 . . . cord-310304-f28tjmi8 233 1 In in IN cord-310304-f28tjmi8 233 2 addition addition NN cord-310304-f28tjmi8 233 3 , , , cord-310304-f28tjmi8 233 4 special special JJ cord-310304-f28tjmi8 233 5 provisions provision NNS cord-310304-f28tjmi8 233 6 should should MD cord-310304-f28tjmi8 233 7 be be VB cord-310304-f28tjmi8 233 8 made make VBN cord-310304-f28tjmi8 233 9 for for IN cord-310304-f28tjmi8 233 10 essential essential JJ cord-310304-f28tjmi8 233 11 workers worker NNS cord-310304-f28tjmi8 233 12 , , , cord-310304-f28tjmi8 233 13 many many DT cord-310304-f28tjmi8 233 14 of of IN cord-310304-f28tjmi8 233 15 whom whom WP cord-310304-f28tjmi8 233 16 are be VBP cord-310304-f28tjmi8 233 17 underserved underserved JJ cord-310304-f28tjmi8 233 18 , , , cord-310304-f28tjmi8 233 19 to to TO cord-310304-f28tjmi8 233 20 be be VB cord-310304-f28tjmi8 233 21 adequately adequately RB cord-310304-f28tjmi8 233 22 equipped equip VBN cord-310304-f28tjmi8 233 23 and and CC cord-310304-f28tjmi8 233 24 compensated compensate VBN cord-310304-f28tjmi8 233 25 for for IN cord-310304-f28tjmi8 233 26 vital vital JJ cord-310304-f28tjmi8 233 27 services service NNS cord-310304-f28tjmi8 233 28 performed perform VBN cord-310304-f28tjmi8 233 29 to to TO cord-310304-f28tjmi8 233 30 maintain maintain VB cord-310304-f28tjmi8 233 31 public public JJ cord-310304-f28tjmi8 233 32 health health NN cord-310304-f28tjmi8 233 33 standards standard NNS cord-310304-f28tjmi8 233 34 . . . cord-310304-f28tjmi8 234 1 Adequate adequate JJ cord-310304-f28tjmi8 234 2 funding funding NN cord-310304-f28tjmi8 234 3 should should MD cord-310304-f28tjmi8 234 4 be be VB cord-310304-f28tjmi8 234 5 established establish VBN cord-310304-f28tjmi8 234 6 to to TO cord-310304-f28tjmi8 234 7 support support VB cord-310304-f28tjmi8 234 8 these these DT cord-310304-f28tjmi8 234 9 initiatives initiative NNS cord-310304-f28tjmi8 234 10 from from IN cord-310304-f28tjmi8 234 11 both both CC cord-310304-f28tjmi8 234 12 the the DT cord-310304-f28tjmi8 234 13 public public JJ cord-310304-f28tjmi8 234 14 and and CC cord-310304-f28tjmi8 234 15 private private JJ cord-310304-f28tjmi8 234 16 sectors sector NNS cord-310304-f28tjmi8 234 17 to to TO cord-310304-f28tjmi8 234 18 avoid avoid VB cord-310304-f28tjmi8 234 19 disruptions disruption NNS cord-310304-f28tjmi8 234 20 in in IN cord-310304-f28tjmi8 234 21 the the DT cord-310304-f28tjmi8 234 22 readiness readiness NN cord-310304-f28tjmi8 234 23 of of IN cord-310304-f28tjmi8 234 24 our -PRON- PRP$ cord-310304-f28tjmi8 234 25 workforce workforce NN cord-310304-f28tjmi8 234 26 , , , cord-310304-f28tjmi8 234 27 supply supply NN cord-310304-f28tjmi8 234 28 chains chain NNS cord-310304-f28tjmi8 234 29 , , , cord-310304-f28tjmi8 234 30 and and CC cord-310304-f28tjmi8 234 31 health health NN cord-310304-f28tjmi8 234 32 care care NN cord-310304-f28tjmi8 234 33 system system NN cord-310304-f28tjmi8 234 34 to to TO cord-310304-f28tjmi8 234 35 prevent prevent VB cord-310304-f28tjmi8 234 36 unforeseen unforeseen JJ cord-310304-f28tjmi8 234 37 economic economic JJ cord-310304-f28tjmi8 234 38 crisis crisis NN cord-310304-f28tjmi8 234 39 . . . cord-310304-f28tjmi8 235 1 New new JJ cord-310304-f28tjmi8 235 2 policies policy NNS cord-310304-f28tjmi8 235 3 must must MD cord-310304-f28tjmi8 235 4 be be VB cord-310304-f28tjmi8 235 5 flexible flexible JJ cord-310304-f28tjmi8 235 6 enough enough RB cord-310304-f28tjmi8 235 7 to to TO cord-310304-f28tjmi8 235 8 accommodate accommodate VB cord-310304-f28tjmi8 235 9 changes change NNS cord-310304-f28tjmi8 235 10 in in IN cord-310304-f28tjmi8 235 11 our -PRON- PRP$ cord-310304-f28tjmi8 235 12 scientific scientific JJ cord-310304-f28tjmi8 235 13 understanding understanding NN cord-310304-f28tjmi8 235 14 of of IN cord-310304-f28tjmi8 235 15 these these DT cord-310304-f28tjmi8 235 16 emerging emerge VBG cord-310304-f28tjmi8 235 17 pathogens pathogen NNS cord-310304-f28tjmi8 235 18 and and CC cord-310304-f28tjmi8 235 19 the the DT cord-310304-f28tjmi8 235 20 development development NN cord-310304-f28tjmi8 235 21 of of IN cord-310304-f28tjmi8 235 22 efficacious efficacious JJ cord-310304-f28tjmi8 235 23 interventions intervention NNS cord-310304-f28tjmi8 235 24 to to TO cord-310304-f28tjmi8 235 25 protect protect VB cord-310304-f28tjmi8 235 26 the the DT cord-310304-f28tjmi8 235 27 public public NN cord-310304-f28tjmi8 235 28 , , , cord-310304-f28tjmi8 235 29 including include VBG cord-310304-f28tjmi8 235 30 our -PRON- PRP$ cord-310304-f28tjmi8 235 31 most most RBS cord-310304-f28tjmi8 235 32 vulnerable vulnerable JJ cord-310304-f28tjmi8 235 33 populations population NNS cord-310304-f28tjmi8 235 34 . . . cord-310304-f28tjmi8 236 1 These these DT cord-310304-f28tjmi8 236 2 policies policy NNS cord-310304-f28tjmi8 236 3 would would MD cord-310304-f28tjmi8 236 4 require require VB cord-310304-f28tjmi8 236 5 a a DT cord-310304-f28tjmi8 236 6 bipartisan bipartisan JJ cord-310304-f28tjmi8 236 7 commitment commitment NN cord-310304-f28tjmi8 236 8 from from IN cord-310304-f28tjmi8 236 9 government government NN cord-310304-f28tjmi8 236 10 officials official NNS cord-310304-f28tjmi8 236 11 , , , cord-310304-f28tjmi8 236 12 ending end VBG cord-310304-f28tjmi8 236 13 a a DT cord-310304-f28tjmi8 236 14 " " `` cord-310304-f28tjmi8 236 15 wait wait VB cord-310304-f28tjmi8 236 16 and and CC cord-310304-f28tjmi8 236 17 see see VB cord-310304-f28tjmi8 236 18 if if IN cord-310304-f28tjmi8 236 19 it -PRON- PRP cord-310304-f28tjmi8 236 20 goes go VBZ cord-310304-f28tjmi8 236 21 away away RB cord-310304-f28tjmi8 236 22 " " '' cord-310304-f28tjmi8 236 23 strategy strategy NN cord-310304-f28tjmi8 236 24 by by IN cord-310304-f28tjmi8 236 25 replacing replace VBG cord-310304-f28tjmi8 236 26 previous previous JJ cord-310304-f28tjmi8 236 27 tactics tactic NNS cord-310304-f28tjmi8 236 28 with with IN cord-310304-f28tjmi8 236 29 a a DT cord-310304-f28tjmi8 236 30 standard standard JJ cord-310304-f28tjmi8 236 31 plan plan NN cord-310304-f28tjmi8 236 32 of of IN cord-310304-f28tjmi8 236 33 action action NN cord-310304-f28tjmi8 236 34 , , , cord-310304-f28tjmi8 236 35 which which WDT cord-310304-f28tjmi8 236 36 would would MD cord-310304-f28tjmi8 236 37 save save VB cord-310304-f28tjmi8 236 38 lives life NNS cord-310304-f28tjmi8 236 39 and and CC cord-310304-f28tjmi8 236 40 reduce reduce VB cord-310304-f28tjmi8 236 41 the the DT cord-310304-f28tjmi8 236 42 overall overall JJ cord-310304-f28tjmi8 236 43 burden burden NN cord-310304-f28tjmi8 236 44 on on IN cord-310304-f28tjmi8 236 45 our -PRON- PRP$ cord-310304-f28tjmi8 236 46 economy economy NN cord-310304-f28tjmi8 236 47 . . . cord-310304-f28tjmi8 237 1 Policy policy NN cord-310304-f28tjmi8 237 2 changes change NNS cord-310304-f28tjmi8 237 3 would would MD cord-310304-f28tjmi8 237 4 include include VB cord-310304-f28tjmi8 237 5 the the DT cord-310304-f28tjmi8 237 6 elimination elimination NN cord-310304-f28tjmi8 237 7 of of IN cord-310304-f28tjmi8 237 8 inequitable inequitable JJ cord-310304-f28tjmi8 237 9 treatment treatment NN cord-310304-f28tjmi8 237 10 within within IN cord-310304-f28tjmi8 237 11 our -PRON- PRP$ cord-310304-f28tjmi8 237 12 health health NN cord-310304-f28tjmi8 237 13 care care NN cord-310304-f28tjmi8 237 14 system system NN cord-310304-f28tjmi8 237 15 . . . cord-310304-f28tjmi8 238 1 Doctor doctor NN cord-310304-f28tjmi8 238 2 - - HYPH cord-310304-f28tjmi8 238 3 patient patient JJ cord-310304-f28tjmi8 238 4 relationships relationship NNS cord-310304-f28tjmi8 238 5 that that WDT cord-310304-f28tjmi8 238 6 include include VBP cord-310304-f28tjmi8 238 7 individuals individual NNS cord-310304-f28tjmi8 238 8 from from IN cord-310304-f28tjmi8 238 9 underserved underserved JJ cord-310304-f28tjmi8 238 10 communities community NNS cord-310304-f28tjmi8 238 11 in in IN cord-310304-f28tjmi8 238 12 the the DT cord-310304-f28tjmi8 238 13 US US NNP cord-310304-f28tjmi8 238 14 can can MD cord-310304-f28tjmi8 238 15 be be VB cord-310304-f28tjmi8 238 16 difficult difficult JJ cord-310304-f28tjmi8 238 17 due due IN cord-310304-f28tjmi8 238 18 to to IN cord-310304-f28tjmi8 238 19 systemic systemic JJ cord-310304-f28tjmi8 238 20 racism racism NN cord-310304-f28tjmi8 238 21 and and CC cord-310304-f28tjmi8 238 22 implicit implicit JJ cord-310304-f28tjmi8 238 23 racial racial JJ cord-310304-f28tjmi8 238 24 bias bias NN cord-310304-f28tjmi8 238 25 that that WDT cord-310304-f28tjmi8 238 26 has have VBZ cord-310304-f28tjmi8 238 27 contributed contribute VBN cord-310304-f28tjmi8 238 28 to to IN cord-310304-f28tjmi8 238 29 historic historic JJ cord-310304-f28tjmi8 238 30 distrust distrust NN cord-310304-f28tjmi8 238 31 in in IN cord-310304-f28tjmi8 238 32 minority minority NN cord-310304-f28tjmi8 238 33 communities community NNS cord-310304-f28tjmi8 238 34 for for IN cord-310304-f28tjmi8 238 35 health health NN cord-310304-f28tjmi8 238 36 care care NN cord-310304-f28tjmi8 238 37 providers provider NNS cord-310304-f28tjmi8 238 38 . . . cord-310304-f28tjmi8 239 1 Physicians physician NNS cord-310304-f28tjmi8 239 2 could could MD cord-310304-f28tjmi8 239 3 engage engage VB cord-310304-f28tjmi8 239 4 minority minority NN cord-310304-f28tjmi8 239 5 patients patient NNS cord-310304-f28tjmi8 239 6 in in IN cord-310304-f28tjmi8 239 7 ways way NNS cord-310304-f28tjmi8 239 8 that that WDT cord-310304-f28tjmi8 239 9 will will MD cord-310304-f28tjmi8 239 10 help help VB cord-310304-f28tjmi8 239 11 to to TO cord-310304-f28tjmi8 239 12 assure assure VB cord-310304-f28tjmi8 239 13 them -PRON- PRP cord-310304-f28tjmi8 239 14 that that IN cord-310304-f28tjmi8 239 15 they -PRON- PRP cord-310304-f28tjmi8 239 16 will will MD cord-310304-f28tjmi8 239 17 receive receive VB cord-310304-f28tjmi8 239 18 the the DT cord-310304-f28tjmi8 239 19 best good JJS cord-310304-f28tjmi8 239 20 possible possible JJ cord-310304-f28tjmi8 239 21 care care NN cord-310304-f28tjmi8 239 22 . . . cord-310304-f28tjmi8 240 1 For for IN cord-310304-f28tjmi8 240 2 those those DT cord-310304-f28tjmi8 240 3 minority minority NN cord-310304-f28tjmi8 240 4 populations population NNS cord-310304-f28tjmi8 240 5 who who WP cord-310304-f28tjmi8 240 6 are be VBP cord-310304-f28tjmi8 240 7 essential essential JJ cord-310304-f28tjmi8 240 8 workers worker NNS cord-310304-f28tjmi8 240 9 that that WDT cord-310304-f28tjmi8 240 10 are be VBP cord-310304-f28tjmi8 240 11 at at IN cord-310304-f28tjmi8 240 12 higher high JJR cord-310304-f28tjmi8 240 13 risk risk NN cord-310304-f28tjmi8 240 14 for for IN cord-310304-f28tjmi8 240 15 Covid-19 covid-19 NN cord-310304-f28tjmi8 240 16 because because IN cord-310304-f28tjmi8 240 17 of of IN cord-310304-f28tjmi8 240 18 pre pre JJ cord-310304-f28tjmi8 240 19 - - JJ cord-310304-f28tjmi8 240 20 existing existing JJ cord-310304-f28tjmi8 240 21 health health NN cord-310304-f28tjmi8 240 22 conditions condition NNS cord-310304-f28tjmi8 240 23 , , , cord-310304-f28tjmi8 240 24 physicians physician NNS cord-310304-f28tjmi8 240 25 should should MD cord-310304-f28tjmi8 240 26 aggressively aggressively RB cord-310304-f28tjmi8 240 27 make make VB cord-310304-f28tjmi8 240 28 them -PRON- PRP cord-310304-f28tjmi8 240 29 aware aware JJ cord-310304-f28tjmi8 240 30 of of IN cord-310304-f28tjmi8 240 31 the the DT cord-310304-f28tjmi8 240 32 risks risk NNS cord-310304-f28tjmi8 240 33 as as RB cord-310304-f28tjmi8 240 34 well well RB cord-310304-f28tjmi8 240 35 as as IN cord-310304-f28tjmi8 240 36 precautionary precautionary JJ cord-310304-f28tjmi8 240 37 measures measure NNS cord-310304-f28tjmi8 240 38 they -PRON- PRP cord-310304-f28tjmi8 240 39 must must MD cord-310304-f28tjmi8 240 40 take take VB cord-310304-f28tjmi8 240 41 to to TO cord-310304-f28tjmi8 240 42 avoid avoid VB cord-310304-f28tjmi8 240 43 infection infection NN cord-310304-f28tjmi8 240 44 . . . cord-310304-f28tjmi8 241 1 Aggressive aggressive JJ cord-310304-f28tjmi8 241 2 strategies strategy NNS cord-310304-f28tjmi8 241 3 to to TO cord-310304-f28tjmi8 241 4 help help VB cord-310304-f28tjmi8 241 5 minority minority NN cord-310304-f28tjmi8 241 6 patients patient NNS cord-310304-f28tjmi8 241 7 at at IN cord-310304-f28tjmi8 241 8 higher high JJR cord-310304-f28tjmi8 241 9 risk risk NN cord-310304-f28tjmi8 241 10 understand understand VBP cord-310304-f28tjmi8 241 11 the the DT cord-310304-f28tjmi8 241 12 seriousness seriousness NN cord-310304-f28tjmi8 241 13 of of IN cord-310304-f28tjmi8 241 14 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 241 15 disease disease NN cord-310304-f28tjmi8 241 16 could could MD cord-310304-f28tjmi8 241 17 include include VB cord-310304-f28tjmi8 241 18 direct direct JJ cord-310304-f28tjmi8 241 19 mailings mailing NNS cord-310304-f28tjmi8 241 20 , , , cord-310304-f28tjmi8 241 21 providing provide VBG cord-310304-f28tjmi8 241 22 patients patient NNS cord-310304-f28tjmi8 241 23 with with IN cord-310304-f28tjmi8 241 24 samples sample NNS cord-310304-f28tjmi8 241 25 of of IN cord-310304-f28tjmi8 241 26 masks mask NNS cord-310304-f28tjmi8 241 27 and and CC cord-310304-f28tjmi8 241 28 sanitizers sanitizer NNS cord-310304-f28tjmi8 241 29 , , , cord-310304-f28tjmi8 241 30 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 241 31 office office NN cord-310304-f28tjmi8 241 32 placards placard NNS cord-310304-f28tjmi8 241 33 , , , cord-310304-f28tjmi8 241 34 COVID-19 covid-19 JJ cord-310304-f28tjmi8 241 35 infomercials infomercial NNS cord-310304-f28tjmi8 241 36 in in IN cord-310304-f28tjmi8 241 37 waiting wait VBG cord-310304-f28tjmi8 241 38 areas area NNS cord-310304-f28tjmi8 241 39 , , , cord-310304-f28tjmi8 241 40 wellness wellness NN cord-310304-f28tjmi8 241 41 checks check NNS cord-310304-f28tjmi8 241 42 , , , cord-310304-f28tjmi8 241 43 and and CC cord-310304-f28tjmi8 241 44 COVID-19 covid-19 VB cord-310304-f28tjmi8 241 45 information information NN cord-310304-f28tjmi8 241 46 for for IN cord-310304-f28tjmi8 241 47 family family NN cord-310304-f28tjmi8 241 48 members member NNS cord-310304-f28tjmi8 241 49 and and CC cord-310304-f28tjmi8 241 50 caretakers caretaker NNS cord-310304-f28tjmi8 241 51 . . . cord-310304-f28tjmi8 242 1 The the DT cord-310304-f28tjmi8 242 2 Social Social NNP cord-310304-f28tjmi8 242 3 Determinants Determinants NNPS cord-310304-f28tjmi8 242 4 of of IN cord-310304-f28tjmi8 242 5 Health Health NNP cord-310304-f28tjmi8 242 6 ( ( -LRB- cord-310304-f28tjmi8 242 7 SDOH SDOH NNP cord-310304-f28tjmi8 242 8 ) ) -RRB- cord-310304-f28tjmi8 242 9 for for IN cord-310304-f28tjmi8 242 10 these these DT cord-310304-f28tjmi8 242 11 individuals individual NNS cord-310304-f28tjmi8 242 12 are be VBP cord-310304-f28tjmi8 242 13 directly directly RB cord-310304-f28tjmi8 242 14 linked link VBN cord-310304-f28tjmi8 242 15 to to IN cord-310304-f28tjmi8 242 16 the the DT cord-310304-f28tjmi8 242 17 development development NN cord-310304-f28tjmi8 242 18 of of IN cord-310304-f28tjmi8 242 19 risk risk NN cord-310304-f28tjmi8 242 20 factors factor NNS cord-310304-f28tjmi8 242 21 that that WDT cord-310304-f28tjmi8 242 22 predispose predispose VBP cord-310304-f28tjmi8 242 23 them -PRON- PRP cord-310304-f28tjmi8 242 24 to to IN cord-310304-f28tjmi8 242 25 more more RBR cord-310304-f28tjmi8 242 26 severe severe JJ cord-310304-f28tjmi8 242 27 COVID-19 covid-19 JJ cord-310304-f28tjmi8 242 28 disease disease NN cord-310304-f28tjmi8 242 29 . . . cord-310304-f28tjmi8 243 1 Healthcare healthcare NN cord-310304-f28tjmi8 243 2 providers provider NNS cord-310304-f28tjmi8 243 3 and and CC cord-310304-f28tjmi8 243 4 patient patient JJ cord-310304-f28tjmi8 243 5 navigators navigator NNS cord-310304-f28tjmi8 243 6 that that WDT cord-310304-f28tjmi8 243 7 have have VBP cord-310304-f28tjmi8 243 8 relationships relationship NNS cord-310304-f28tjmi8 243 9 with with IN cord-310304-f28tjmi8 243 10 community community NN cord-310304-f28tjmi8 243 11 based base VBN cord-310304-f28tjmi8 243 12 organizations organization NNS cord-310304-f28tjmi8 243 13 ( ( -LRB- cord-310304-f28tjmi8 243 14 CBOs CBOs NNP cord-310304-f28tjmi8 243 15 ) ) -RRB- cord-310304-f28tjmi8 243 16 that that WDT cord-310304-f28tjmi8 243 17 work work VBP cord-310304-f28tjmi8 243 18 to to TO cord-310304-f28tjmi8 243 19 improve improve VB cord-310304-f28tjmi8 243 20 SDOH SDOH NNP cord-310304-f28tjmi8 243 21 among among IN cord-310304-f28tjmi8 243 22 underserved underserved JJ cord-310304-f28tjmi8 243 23 communities community NNS cord-310304-f28tjmi8 243 24 could could MD cord-310304-f28tjmi8 243 25 be be VB cord-310304-f28tjmi8 243 26 an an DT cord-310304-f28tjmi8 243 27 important important JJ cord-310304-f28tjmi8 243 28 option option NN cord-310304-f28tjmi8 243 29 to to TO cord-310304-f28tjmi8 243 30 support support VB cord-310304-f28tjmi8 243 31 the the DT cord-310304-f28tjmi8 243 32 long long JJ cord-310304-f28tjmi8 243 33 term term NN cord-310304-f28tjmi8 243 34 health health NN cord-310304-f28tjmi8 243 35 and and CC cord-310304-f28tjmi8 243 36 wellness wellness NN cord-310304-f28tjmi8 243 37 of of IN cord-310304-f28tjmi8 243 38 disparity disparity NN cord-310304-f28tjmi8 243 39 populations population NNS cord-310304-f28tjmi8 243 40 . . . cord-310304-f28tjmi8 244 1 Front front JJ cord-310304-f28tjmi8 244 2 line line NN cord-310304-f28tjmi8 244 3 health health NN cord-310304-f28tjmi8 244 4 care care NN cord-310304-f28tjmi8 244 5 providers provider NNS cord-310304-f28tjmi8 244 6 in in IN cord-310304-f28tjmi8 244 7 the the DT cord-310304-f28tjmi8 244 8 Covid-19 covid-19 JJ cord-310304-f28tjmi8 244 9 pandemic pandemic NN cord-310304-f28tjmi8 244 10 are be VBP cord-310304-f28tjmi8 244 11 being be VBG cord-310304-f28tjmi8 244 12 pushed push VBN cord-310304-f28tjmi8 244 13 to to IN cord-310304-f28tjmi8 244 14 the the DT cord-310304-f28tjmi8 244 15 limits limit NNS cord-310304-f28tjmi8 244 16 of of IN cord-310304-f28tjmi8 244 17 human human JJ cord-310304-f28tjmi8 244 18 endurance endurance NN cord-310304-f28tjmi8 244 19 and and CC cord-310304-f28tjmi8 244 20 are be VBP cord-310304-f28tjmi8 244 21 often often RB cord-310304-f28tjmi8 244 22 overwhelmed overwhelmed JJ cord-310304-f28tjmi8 244 23 which which WDT cord-310304-f28tjmi8 244 24 can can MD cord-310304-f28tjmi8 244 25 trigger trigger VB cord-310304-f28tjmi8 244 26 disparate disparate JJ cord-310304-f28tjmi8 244 27 responses response NNS cord-310304-f28tjmi8 244 28 to to IN cord-310304-f28tjmi8 244 29 minority minority NN cord-310304-f28tjmi8 244 30 communities community NNS cord-310304-f28tjmi8 244 31 . . . cord-310304-f28tjmi8 245 1 Policies policy NNS cord-310304-f28tjmi8 245 2 need need VBP cord-310304-f28tjmi8 245 3 to to TO cord-310304-f28tjmi8 245 4 be be VB cord-310304-f28tjmi8 245 5 in in IN cord-310304-f28tjmi8 245 6 place place NN cord-310304-f28tjmi8 245 7 that that WDT cord-310304-f28tjmi8 245 8 confer confer VBP cord-310304-f28tjmi8 245 9 oversight oversight NN cord-310304-f28tjmi8 245 10 for for IN cord-310304-f28tjmi8 245 11 when when WRB cord-310304-f28tjmi8 245 12 this this DT cord-310304-f28tjmi8 245 13 occurs occur VBZ cord-310304-f28tjmi8 245 14 . . . cord-310304-f28tjmi8 246 1 Physicians physician NNS cord-310304-f28tjmi8 246 2 should should MD cord-310304-f28tjmi8 246 3 be be VB cord-310304-f28tjmi8 246 4 surveyed survey VBN cord-310304-f28tjmi8 246 5 in in IN cord-310304-f28tjmi8 246 6 ways way NNS cord-310304-f28tjmi8 246 7 to to TO cord-310304-f28tjmi8 246 8 recognize recognize VB cord-310304-f28tjmi8 246 9 implicit implicit JJ cord-310304-f28tjmi8 246 10 racial racial JJ cord-310304-f28tjmi8 246 11 bias bias NN cord-310304-f28tjmi8 246 12 when when WRB cord-310304-f28tjmi8 246 13 caring care VBG cord-310304-f28tjmi8 246 14 for for IN cord-310304-f28tjmi8 246 15 minority minority NN cord-310304-f28tjmi8 246 16 patients patient NNS cord-310304-f28tjmi8 246 17 and and CC cord-310304-f28tjmi8 246 18 be be VB cord-310304-f28tjmi8 246 19 encouraged encourage VBN cord-310304-f28tjmi8 246 20 to to TO cord-310304-f28tjmi8 246 21 take take VB cord-310304-f28tjmi8 246 22 measures measure NNS cord-310304-f28tjmi8 246 23 to to TO cord-310304-f28tjmi8 246 24 constructively constructively RB cord-310304-f28tjmi8 246 25 modify modify VB cord-310304-f28tjmi8 246 26 their -PRON- PRP$ cord-310304-f28tjmi8 246 27 behavior behavior NN cord-310304-f28tjmi8 246 28 . . . cord-310304-f28tjmi8 247 1 In in IN cord-310304-f28tjmi8 247 2 addition addition NN cord-310304-f28tjmi8 247 3 , , , cord-310304-f28tjmi8 247 4 there there EX cord-310304-f28tjmi8 247 5 is be VBZ cord-310304-f28tjmi8 247 6 a a DT cord-310304-f28tjmi8 247 7 great great JJ cord-310304-f28tjmi8 247 8 need need NN cord-310304-f28tjmi8 247 9 for for IN cord-310304-f28tjmi8 247 10 more more JJR cord-310304-f28tjmi8 247 11 nurses nurse NNS cord-310304-f28tjmi8 247 12 and and CC cord-310304-f28tjmi8 247 13 other other JJ cord-310304-f28tjmi8 247 14 medical medical JJ cord-310304-f28tjmi8 247 15 practitioners practitioner NNS cord-310304-f28tjmi8 247 16 to to TO cord-310304-f28tjmi8 247 17 support support VB cord-310304-f28tjmi8 247 18 physicians physician NNS cord-310304-f28tjmi8 247 19 during during IN cord-310304-f28tjmi8 247 20 this this DT cord-310304-f28tjmi8 247 21 pandemic pandemic NN cord-310304-f28tjmi8 247 22 . . . cord-310304-f28tjmi8 248 1 Some some DT cord-310304-f28tjmi8 248 2 of of IN cord-310304-f28tjmi8 248 3 these these DT cord-310304-f28tjmi8 248 4 challenges challenge NNS cord-310304-f28tjmi8 248 5 can can MD cord-310304-f28tjmi8 248 6 be be VB cord-310304-f28tjmi8 248 7 met meet VBN cord-310304-f28tjmi8 248 8 with with IN cord-310304-f28tjmi8 248 9 volunteers volunteer NNS cord-310304-f28tjmi8 248 10 that that WDT cord-310304-f28tjmi8 248 11 have have VBP cord-310304-f28tjmi8 248 12 past past JJ cord-310304-f28tjmi8 248 13 medical medical JJ cord-310304-f28tjmi8 248 14 training training NN cord-310304-f28tjmi8 248 15 as as RB cord-310304-f28tjmi8 248 16 well well RB cord-310304-f28tjmi8 248 17 as as IN cord-310304-f28tjmi8 248 18 military military JJ cord-310304-f28tjmi8 248 19 medical medical JJ cord-310304-f28tjmi8 248 20 staff staff NN cord-310304-f28tjmi8 248 21 . . . cord-310304-f28tjmi8 249 1 Essential essential JJ cord-310304-f28tjmi8 249 2 workers worker NNS cord-310304-f28tjmi8 249 3 , , , cord-310304-f28tjmi8 249 4 many many DT cord-310304-f28tjmi8 249 5 of of IN cord-310304-f28tjmi8 249 6 whom whom WP cord-310304-f28tjmi8 249 7 are be VBP cord-310304-f28tjmi8 249 8 from from IN cord-310304-f28tjmi8 249 9 minority minority NN cord-310304-f28tjmi8 249 10 communities community NNS cord-310304-f28tjmi8 249 11 are be VBP cord-310304-f28tjmi8 249 12 often often RB cord-310304-f28tjmi8 249 13 forced force VBN cord-310304-f28tjmi8 249 14 to to TO cord-310304-f28tjmi8 249 15 experience experience VB cord-310304-f28tjmi8 249 16 increased increase VBN cord-310304-f28tjmi8 249 17 risk risk NN cord-310304-f28tjmi8 249 18 of of IN cord-310304-f28tjmi8 249 19 virus virus NN cord-310304-f28tjmi8 249 20 transmission transmission NN cord-310304-f28tjmi8 249 21 because because IN cord-310304-f28tjmi8 249 22 of of IN cord-310304-f28tjmi8 249 23 economic economic JJ cord-310304-f28tjmi8 249 24 hardships hardship NNS cord-310304-f28tjmi8 249 25 and and CC cord-310304-f28tjmi8 249 26 the the DT cord-310304-f28tjmi8 249 27 lack lack NN cord-310304-f28tjmi8 249 28 of of IN cord-310304-f28tjmi8 249 29 personal personal JJ cord-310304-f28tjmi8 249 30 protective protective JJ cord-310304-f28tjmi8 249 31 equipment equipment NN cord-310304-f28tjmi8 249 32 ( ( -LRB- cord-310304-f28tjmi8 249 33 PPE PPE NNP cord-310304-f28tjmi8 249 34 ) ) -RRB- cord-310304-f28tjmi8 249 35 . . . cord-310304-f28tjmi8 250 1 The the DT cord-310304-f28tjmi8 250 2 lack lack NN cord-310304-f28tjmi8 250 3 of of IN cord-310304-f28tjmi8 250 4 PPE PPE NNP cord-310304-f28tjmi8 250 5 is be VBZ cord-310304-f28tjmi8 250 6 directly directly RB cord-310304-f28tjmi8 250 7 linked link VBN cord-310304-f28tjmi8 250 8 to to IN cord-310304-f28tjmi8 250 9 the the DT cord-310304-f28tjmi8 250 10 likelihood likelihood NN cord-310304-f28tjmi8 250 11 of of IN cord-310304-f28tjmi8 250 12 virus virus NN cord-310304-f28tjmi8 250 13 transmission transmission NN cord-310304-f28tjmi8 250 14 to to IN cord-310304-f28tjmi8 250 15 essential essential JJ cord-310304-f28tjmi8 250 16 workers worker NNS cord-310304-f28tjmi8 250 17 and and CC cord-310304-f28tjmi8 250 18 , , , cord-310304-f28tjmi8 250 19 therefore therefore RB cord-310304-f28tjmi8 250 20 , , , cord-310304-f28tjmi8 250 21 should should MD cord-310304-f28tjmi8 250 22 be be VB cord-310304-f28tjmi8 250 23 recognized recognize VBN cord-310304-f28tjmi8 250 24 as as IN cord-310304-f28tjmi8 250 25 a a DT cord-310304-f28tjmi8 250 26 necessity necessity NN cord-310304-f28tjmi8 250 27 that that WDT cord-310304-f28tjmi8 250 28 should should MD cord-310304-f28tjmi8 250 29 be be VB cord-310304-f28tjmi8 250 30 prioritized prioritize VBN cord-310304-f28tjmi8 250 31 by by IN cord-310304-f28tjmi8 250 32 the the DT cord-310304-f28tjmi8 250 33 federal federal JJ cord-310304-f28tjmi8 250 34 government government NN cord-310304-f28tjmi8 250 35 as as IN cord-310304-f28tjmi8 250 36 an an DT cord-310304-f28tjmi8 250 37 emergency emergency NN cord-310304-f28tjmi8 250 38 declaration declaration NN cord-310304-f28tjmi8 250 39 that that WDT cord-310304-f28tjmi8 250 40 would would MD cord-310304-f28tjmi8 250 41 be be VB cord-310304-f28tjmi8 250 42 fully fully RB cord-310304-f28tjmi8 250 43 funded fund VBN cord-310304-f28tjmi8 250 44 throughout throughout IN cord-310304-f28tjmi8 250 45 this this DT cord-310304-f28tjmi8 250 46 pandemic pandemic NN cord-310304-f28tjmi8 250 47 and and CC cord-310304-f28tjmi8 250 48 policies policy NNS cord-310304-f28tjmi8 250 49 put put VBN cord-310304-f28tjmi8 250 50 in in IN cord-310304-f28tjmi8 250 51 place place NN cord-310304-f28tjmi8 250 52 in in IN cord-310304-f28tjmi8 250 53 this this DT cord-310304-f28tjmi8 250 54 declaration declaration NN cord-310304-f28tjmi8 250 55 for for IN cord-310304-f28tjmi8 250 56 timely timely RB cord-310304-f28tjmi8 250 57 ramping ramp VBG cord-310304-f28tjmi8 250 58 - - HYPH cord-310304-f28tjmi8 250 59 up up NN cord-310304-f28tjmi8 250 60 of of IN cord-310304-f28tjmi8 250 61 PPE PPE NNP cord-310304-f28tjmi8 250 62 supplies supply NNS cord-310304-f28tjmi8 250 63 and and CC cord-310304-f28tjmi8 250 64 development development NN cord-310304-f28tjmi8 250 65 of of IN cord-310304-f28tjmi8 250 66 government government NN cord-310304-f28tjmi8 250 67 - - HYPH cord-310304-f28tjmi8 250 68 owned own VBN cord-310304-f28tjmi8 250 69 PPE PPE NNP cord-310304-f28tjmi8 250 70 stockpiles stockpile NNS cord-310304-f28tjmi8 250 71 for for IN cord-310304-f28tjmi8 250 72 a a DT cord-310304-f28tjmi8 250 73 future future JJ cord-310304-f28tjmi8 250 74 medical medical JJ cord-310304-f28tjmi8 250 75 crisis crisis NN cord-310304-f28tjmi8 250 76 . . . cord-310304-f28tjmi8 251 1 A a DT cord-310304-f28tjmi8 251 2 commission commission NN cord-310304-f28tjmi8 251 3 of of IN cord-310304-f28tjmi8 251 4 physicians physician NNS cord-310304-f28tjmi8 251 5 , , , cord-310304-f28tjmi8 251 6 and and CC cord-310304-f28tjmi8 251 7 nurses nurse NNS cord-310304-f28tjmi8 251 8 should should MD cord-310304-f28tjmi8 251 9 be be VB cord-310304-f28tjmi8 251 10 established establish VBN cord-310304-f28tjmi8 251 11 to to TO cord-310304-f28tjmi8 251 12 advocate advocate VB cord-310304-f28tjmi8 251 13 the the DT cord-310304-f28tjmi8 251 14 need need NN cord-310304-f28tjmi8 251 15 for for IN cord-310304-f28tjmi8 251 16 PPE PPE NNP cord-310304-f28tjmi8 251 17 on on IN cord-310304-f28tjmi8 251 18 behalf behalf NN cord-310304-f28tjmi8 251 19 of of IN cord-310304-f28tjmi8 251 20 essential essential JJ cord-310304-f28tjmi8 251 21 workers worker NNS cord-310304-f28tjmi8 251 22 at at IN cord-310304-f28tjmi8 251 23 risk risk NN cord-310304-f28tjmi8 251 24 for for IN cord-310304-f28tjmi8 251 25 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 251 26 and and CC cord-310304-f28tjmi8 251 27 given give VBN cord-310304-f28tjmi8 251 28 the the DT cord-310304-f28tjmi8 251 29 opportunity opportunity NN cord-310304-f28tjmi8 251 30 the the DT cord-310304-f28tjmi8 251 31 make make VBP cord-310304-f28tjmi8 251 32 their -PRON- PRP$ cord-310304-f28tjmi8 251 33 case case NN cord-310304-f28tjmi8 251 34 to to IN cord-310304-f28tjmi8 251 35 policy policy NN cord-310304-f28tjmi8 251 36 makers maker NNS cord-310304-f28tjmi8 251 37 . . . cord-310304-f28tjmi8 252 1 Healthcare healthcare NN cord-310304-f28tjmi8 252 2 access access NN cord-310304-f28tjmi8 252 3 is be VBZ cord-310304-f28tjmi8 252 4 a a DT cord-310304-f28tjmi8 252 5 core core NN cord-310304-f28tjmi8 252 6 component component NN cord-310304-f28tjmi8 252 7 of of IN cord-310304-f28tjmi8 252 8 the the DT cord-310304-f28tjmi8 252 9 SDOH SDOH NNP cord-310304-f28tjmi8 252 10 for for IN cord-310304-f28tjmi8 252 11 underserved underserved JJ cord-310304-f28tjmi8 252 12 communities community NNS cord-310304-f28tjmi8 252 13 and and CC cord-310304-f28tjmi8 252 14 poor poor JJ cord-310304-f28tjmi8 252 15 access access NN cord-310304-f28tjmi8 252 16 to to IN cord-310304-f28tjmi8 252 17 affordable affordable JJ cord-310304-f28tjmi8 252 18 healthcare healthcare NN cord-310304-f28tjmi8 252 19 is be VBZ cord-310304-f28tjmi8 252 20 a a DT cord-310304-f28tjmi8 252 21 major major JJ cord-310304-f28tjmi8 252 22 driver driver NN cord-310304-f28tjmi8 252 23 of of IN cord-310304-f28tjmi8 252 24 health health NN cord-310304-f28tjmi8 252 25 disparities disparity NNS cord-310304-f28tjmi8 252 26 in in IN cord-310304-f28tjmi8 252 27 the the DT cord-310304-f28tjmi8 252 28 US US NNP cord-310304-f28tjmi8 252 29 . . . cord-310304-f28tjmi8 253 1 These these DT cord-310304-f28tjmi8 253 2 disparity disparity NN cord-310304-f28tjmi8 253 3 populations population NNS cord-310304-f28tjmi8 253 4 are be VBP cord-310304-f28tjmi8 253 5 heavily heavily RB cord-310304-f28tjmi8 253 6 impacted impact VBN cord-310304-f28tjmi8 253 7 by by IN cord-310304-f28tjmi8 253 8 this this DT cord-310304-f28tjmi8 253 9 pandemic pandemic NN cord-310304-f28tjmi8 253 10 . . . cord-310304-f28tjmi8 254 1 The the DT cord-310304-f28tjmi8 254 2 Affordable Affordable NNP cord-310304-f28tjmi8 254 3 Care Care NNP cord-310304-f28tjmi8 254 4 Act Act NNP cord-310304-f28tjmi8 254 5 ( ( -LRB- cord-310304-f28tjmi8 254 6 ACA ACA NNP cord-310304-f28tjmi8 254 7 ) ) -RRB- cord-310304-f28tjmi8 254 8 represents represent VBZ cord-310304-f28tjmi8 254 9 a a DT cord-310304-f28tjmi8 254 10 lifeline lifeline NN cord-310304-f28tjmi8 254 11 for for IN cord-310304-f28tjmi8 254 12 the the DT cord-310304-f28tjmi8 254 13 working work VBG cord-310304-f28tjmi8 254 14 poor poor JJ cord-310304-f28tjmi8 254 15 and and CC cord-310304-f28tjmi8 254 16 their -PRON- PRP$ cord-310304-f28tjmi8 254 17 families family NNS cord-310304-f28tjmi8 254 18 without without IN cord-310304-f28tjmi8 254 19 health health NN cord-310304-f28tjmi8 254 20 insurance insurance NN cord-310304-f28tjmi8 254 21 . . . cord-310304-f28tjmi8 255 1 The the DT cord-310304-f28tjmi8 255 2 ACA ACA NNP cord-310304-f28tjmi8 255 3 should should MD cord-310304-f28tjmi8 255 4 be be VB cord-310304-f28tjmi8 255 5 maintained maintain VBN cord-310304-f28tjmi8 255 6 and and CC cord-310304-f28tjmi8 255 7 arguably arguably RB cord-310304-f28tjmi8 255 8 updated update VBN cord-310304-f28tjmi8 255 9 or or CC cord-310304-f28tjmi8 255 10 revised revise VBN cord-310304-f28tjmi8 255 11 to to TO cord-310304-f28tjmi8 255 12 meet meet VB cord-310304-f28tjmi8 255 13 the the DT cord-310304-f28tjmi8 255 14 changing change VBG cord-310304-f28tjmi8 255 15 needs need NNS cord-310304-f28tjmi8 255 16 of of IN cord-310304-f28tjmi8 255 17 participants participant NNS cord-310304-f28tjmi8 255 18 . . . cord-310304-f28tjmi8 256 1 The the DT cord-310304-f28tjmi8 256 2 ACA ACA NNP cord-310304-f28tjmi8 256 3 is be VBZ cord-310304-f28tjmi8 256 4 a a DT cord-310304-f28tjmi8 256 5 critical critical JJ cord-310304-f28tjmi8 256 6 component component NN cord-310304-f28tjmi8 256 7 of of IN cord-310304-f28tjmi8 256 8 our -PRON- PRP$ cord-310304-f28tjmi8 256 9 existing exist VBG cord-310304-f28tjmi8 256 10 healthcare healthcare NN cord-310304-f28tjmi8 256 11 infrastructure infrastructure NN cord-310304-f28tjmi8 256 12 that that WDT cord-310304-f28tjmi8 256 13 directly directly RB cord-310304-f28tjmi8 256 14 addresses address VBZ cord-310304-f28tjmi8 256 15 health health NN cord-310304-f28tjmi8 256 16 inequities inequity NNS cord-310304-f28tjmi8 256 17 in in IN cord-310304-f28tjmi8 256 18 the the DT cord-310304-f28tjmi8 256 19 US US NNP cord-310304-f28tjmi8 256 20 and and CC cord-310304-f28tjmi8 256 21 is be VBZ cord-310304-f28tjmi8 256 22 not not RB cord-310304-f28tjmi8 256 23 perfect perfect JJ cord-310304-f28tjmi8 256 24 in in IN cord-310304-f28tjmi8 256 25 content content NN cord-310304-f28tjmi8 256 26 and and CC cord-310304-f28tjmi8 256 27 yet yet RB cord-310304-f28tjmi8 256 28 should should MD cord-310304-f28tjmi8 256 29 be be VB cord-310304-f28tjmi8 256 30 preserved preserve VBN cord-310304-f28tjmi8 256 31 . . . cord-310304-f28tjmi8 257 1 The the DT cord-310304-f28tjmi8 257 2 existing exist VBG cord-310304-f28tjmi8 257 3 political political JJ cord-310304-f28tjmi8 257 4 climate climate NN cord-310304-f28tjmi8 257 5 for for IN cord-310304-f28tjmi8 257 6 legislation legislation NN cord-310304-f28tjmi8 257 7 to to TO cord-310304-f28tjmi8 257 8 directly directly RB cord-310304-f28tjmi8 257 9 address address VB cord-310304-f28tjmi8 257 10 longstanding longstanding JJ cord-310304-f28tjmi8 257 11 US US NNP cord-310304-f28tjmi8 257 12 racial racial JJ cord-310304-f28tjmi8 257 13 / / SYM cord-310304-f28tjmi8 257 14 ethnic ethnic JJ cord-310304-f28tjmi8 257 15 inequities inequity NNS cord-310304-f28tjmi8 257 16 in in IN cord-310304-f28tjmi8 257 17 healthcare healthcare NN cord-310304-f28tjmi8 257 18 as as RB cord-310304-f28tjmi8 257 19 well well RB cord-310304-f28tjmi8 257 20 as as IN cord-310304-f28tjmi8 257 21 other other JJ cord-310304-f28tjmi8 257 22 SDOH SDOH NNP cord-310304-f28tjmi8 257 23 such such JJ cord-310304-f28tjmi8 257 24 as as IN cord-310304-f28tjmi8 257 25 education education NN cord-310304-f28tjmi8 257 26 , , , cord-310304-f28tjmi8 257 27 housing housing NN cord-310304-f28tjmi8 257 28 , , , cord-310304-f28tjmi8 257 29 and and CC cord-310304-f28tjmi8 257 30 a a DT cord-310304-f28tjmi8 257 31 living living NN cord-310304-f28tjmi8 257 32 wage wage NN cord-310304-f28tjmi8 257 33 will will MD cord-310304-f28tjmi8 257 34 require require VB cord-310304-f28tjmi8 257 35 a a DT cord-310304-f28tjmi8 257 36 continuance continuance NN cord-310304-f28tjmi8 257 37 of of IN cord-310304-f28tjmi8 257 38 the the DT cord-310304-f28tjmi8 257 39 grass grass NN cord-310304-f28tjmi8 257 40 roots root NNS cord-310304-f28tjmi8 257 41 call call VBP cord-310304-f28tjmi8 257 42 for for IN cord-310304-f28tjmi8 257 43 change change NN cord-310304-f28tjmi8 257 44 and and CC cord-310304-f28tjmi8 257 45 the the DT cord-310304-f28tjmi8 257 46 acceptance acceptance NN cord-310304-f28tjmi8 257 47 by by IN cord-310304-f28tjmi8 257 48 policy policy NN cord-310304-f28tjmi8 257 49 makers maker NNS cord-310304-f28tjmi8 257 50 that that IN cord-310304-f28tjmi8 257 51 these these DT cord-310304-f28tjmi8 257 52 changes change NNS cord-310304-f28tjmi8 257 53 need need VBP cord-310304-f28tjmi8 257 54 to to TO cord-310304-f28tjmi8 257 55 become become VB cord-310304-f28tjmi8 257 56 law law NN cord-310304-f28tjmi8 257 57 in in IN cord-310304-f28tjmi8 257 58 America America NNP cord-310304-f28tjmi8 257 59 . . . cord-310304-f28tjmi8 258 1 Longstanding longstanding JJ cord-310304-f28tjmi8 258 2 health health NN cord-310304-f28tjmi8 258 3 disparities disparity NNS cord-310304-f28tjmi8 258 4 such such JJ cord-310304-f28tjmi8 258 5 as as IN cord-310304-f28tjmi8 258 6 diabetes diabetes NN cord-310304-f28tjmi8 258 7 , , , cord-310304-f28tjmi8 258 8 hypertension hypertension NN cord-310304-f28tjmi8 258 9 , , , cord-310304-f28tjmi8 258 10 CVD CVD NNP cord-310304-f28tjmi8 258 11 , , , cord-310304-f28tjmi8 258 12 and and CC cord-310304-f28tjmi8 258 13 pulmonary pulmonary JJ cord-310304-f28tjmi8 258 14 disease disease NN cord-310304-f28tjmi8 258 15 among among IN cord-310304-f28tjmi8 258 16 minority minority NN cord-310304-f28tjmi8 258 17 populations population NNS cord-310304-f28tjmi8 258 18 in in IN cord-310304-f28tjmi8 258 19 the the DT cord-310304-f28tjmi8 258 20 US US NNP cord-310304-f28tjmi8 258 21 may may MD cord-310304-f28tjmi8 258 22 serve serve VB cord-310304-f28tjmi8 258 23 to to TO cord-310304-f28tjmi8 258 24 predispose predispose VB cord-310304-f28tjmi8 258 25 these these DT cord-310304-f28tjmi8 258 26 communities community NNS cord-310304-f28tjmi8 258 27 to to IN cord-310304-f28tjmi8 258 28 SARS SARS NNP cord-310304-f28tjmi8 258 29 - - HYPH cord-310304-f28tjmi8 258 30 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 258 31 infection infection NN cord-310304-f28tjmi8 258 32 and and CC cord-310304-f28tjmi8 258 33 increased increase VBN cord-310304-f28tjmi8 258 34 risk risk NN cord-310304-f28tjmi8 258 35 for for IN cord-310304-f28tjmi8 258 36 clinically clinically RB cord-310304-f28tjmi8 258 37 severe severe JJ cord-310304-f28tjmi8 258 38 COVID-19 covid-19 NN cord-310304-f28tjmi8 258 39 . . . cord-310304-f28tjmi8 259 1 The the DT cord-310304-f28tjmi8 259 2 underlying underlying JJ cord-310304-f28tjmi8 259 3 social social JJ cord-310304-f28tjmi8 259 4 determinants determinant NNS cord-310304-f28tjmi8 259 5 of of IN cord-310304-f28tjmi8 259 6 health health NN cord-310304-f28tjmi8 259 7 and and CC cord-310304-f28tjmi8 259 8 standards standard NNS cord-310304-f28tjmi8 259 9 of of IN cord-310304-f28tjmi8 259 10 care care NN cord-310304-f28tjmi8 259 11 in in IN cord-310304-f28tjmi8 259 12 minority minority NN cord-310304-f28tjmi8 259 13 communities community NNS cord-310304-f28tjmi8 259 14 must must MD cord-310304-f28tjmi8 259 15 be be VB cord-310304-f28tjmi8 259 16 improved improve VBN cord-310304-f28tjmi8 259 17 to to TO cord-310304-f28tjmi8 259 18 end end VB cord-310304-f28tjmi8 259 19 these these DT cord-310304-f28tjmi8 259 20 disparities disparity NNS cord-310304-f28tjmi8 259 21 . . . cord-310304-f28tjmi8 260 1 Improvements improvement NNS cord-310304-f28tjmi8 260 2 will will MD cord-310304-f28tjmi8 260 3 require require VB cord-310304-f28tjmi8 260 4 changes change NNS cord-310304-f28tjmi8 260 5 in in IN cord-310304-f28tjmi8 260 6 governmental governmental JJ cord-310304-f28tjmi8 260 7 policy policy NN cord-310304-f28tjmi8 260 8 and and CC cord-310304-f28tjmi8 260 9 a a DT cord-310304-f28tjmi8 260 10 long long JJ cord-310304-f28tjmi8 260 11 - - HYPH cord-310304-f28tjmi8 260 12 term term NN cord-310304-f28tjmi8 260 13 commitment commitment NN cord-310304-f28tjmi8 260 14 to to IN cord-310304-f28tjmi8 260 15 minority minority NN cord-310304-f28tjmi8 260 16 communities community NNS cord-310304-f28tjmi8 260 17 that that WDT cord-310304-f28tjmi8 260 18 includes include VBZ cord-310304-f28tjmi8 260 19 early early JJ cord-310304-f28tjmi8 260 20 interventions intervention NNS cord-310304-f28tjmi8 260 21 and and CC cord-310304-f28tjmi8 260 22 prevention prevention NN cord-310304-f28tjmi8 260 23 strategies strategy NNS cord-310304-f28tjmi8 260 24 to to TO cord-310304-f28tjmi8 260 25 reduce reduce VB cord-310304-f28tjmi8 260 26 or or CC cord-310304-f28tjmi8 260 27 eliminate eliminate VB cord-310304-f28tjmi8 260 28 major major JJ cord-310304-f28tjmi8 260 29 healthy healthy JJ cord-310304-f28tjmi8 260 30 disparities disparity NNS cord-310304-f28tjmi8 260 31 on on IN cord-310304-f28tjmi8 260 32 the the DT cord-310304-f28tjmi8 260 33 way way NN cord-310304-f28tjmi8 260 34 to to IN cord-310304-f28tjmi8 260 35 achieving achieve VBG cord-310304-f28tjmi8 260 36 health health NN cord-310304-f28tjmi8 260 37 equity equity NN cord-310304-f28tjmi8 260 38 . . . cord-310304-f28tjmi8 261 1 The the DT cord-310304-f28tjmi8 261 2 novel novel JJ cord-310304-f28tjmi8 261 3 Chinese chinese JJ cord-310304-f28tjmi8 261 4 coronavirus coronavirus NN cord-310304-f28tjmi8 261 5 ( ( -LRB- cord-310304-f28tjmi8 261 6 2019-nCoV 2019-ncov CD cord-310304-f28tjmi8 261 7 ) ) -RRB- cord-310304-f28tjmi8 261 8 infections infection NNS cord-310304-f28tjmi8 261 9 : : : cord-310304-f28tjmi8 261 10 Challenges challenge NNS cord-310304-f28tjmi8 261 11 for for IN cord-310304-f28tjmi8 261 12 fighting fight VBG cord-310304-f28tjmi8 261 13 the the DT cord-310304-f28tjmi8 261 14 storm storm NN cord-310304-f28tjmi8 261 15 Severe severe JJ cord-310304-f28tjmi8 261 16 acute acute JJ cord-310304-f28tjmi8 261 17 respiratory respiratory JJ cord-310304-f28tjmi8 261 18 syndrome syndrome NN cord-310304-f28tjmi8 261 19 coronavirus coronavirus NN cord-310304-f28tjmi8 261 20 2 2 CD cord-310304-f28tjmi8 261 21 ( ( -LRB- cord-310304-f28tjmi8 261 22 SARS SARS NNP cord-310304-f28tjmi8 261 23 - - HYPH cord-310304-f28tjmi8 261 24 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 261 25 ) ) -RRB- cord-310304-f28tjmi8 261 26 and and CC cord-310304-f28tjmi8 261 27 coronavirus coronavirus NN cord-310304-f28tjmi8 261 28 disease-2019 disease-2019 NNP cord-310304-f28tjmi8 261 29 ( ( -LRB- cord-310304-f28tjmi8 261 30 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 261 31 ) ) -RRB- cord-310304-f28tjmi8 261 32 : : : cord-310304-f28tjmi8 262 1 The the DT cord-310304-f28tjmi8 262 2 epidemic epidemic NN cord-310304-f28tjmi8 262 3 and and CC cord-310304-f28tjmi8 262 4 the the DT cord-310304-f28tjmi8 262 5 challenges challenge NNS cord-310304-f28tjmi8 262 6 Faculty Faculty NNP cord-310304-f28tjmi8 262 7 Opinions opinion NNS cord-310304-f28tjmi8 262 8 recommendation recommendation NN cord-310304-f28tjmi8 262 9 of of IN cord-310304-f28tjmi8 262 10 Early Early NNP cord-310304-f28tjmi8 262 11 Transmission Transmission NNP cord-310304-f28tjmi8 262 12 Dynamics Dynamics NNPS cord-310304-f28tjmi8 262 13 in in IN cord-310304-f28tjmi8 262 14 Wuhan Wuhan NNP cord-310304-f28tjmi8 262 15 , , , cord-310304-f28tjmi8 262 16 China China NNP cord-310304-f28tjmi8 262 17 , , , cord-310304-f28tjmi8 262 18 of of IN cord-310304-f28tjmi8 262 19 Novel Novel NNP cord-310304-f28tjmi8 262 20 Coronavirus Coronavirus NNP cord-310304-f28tjmi8 262 21 - - HYPH cord-310304-f28tjmi8 262 22 Infected infect VBN cord-310304-f28tjmi8 262 23 Pneumonia Pneumonia NNP cord-310304-f28tjmi8 262 24 . . . cord-310304-f28tjmi8 263 1 Faculty faculty NN cord-310304-f28tjmi8 263 2 Opinions opinion NNS cord-310304-f28tjmi8 263 3 - - HYPH cord-310304-f28tjmi8 263 4 Post Post NNP cord-310304-f28tjmi8 263 5 - - HYPH cord-310304-f28tjmi8 263 6 Publication Publication NNP cord-310304-f28tjmi8 263 7 Peer Peer NNP cord-310304-f28tjmi8 263 8 Review Review NNP cord-310304-f28tjmi8 263 9 of of IN cord-310304-f28tjmi8 263 10 the the DT cord-310304-f28tjmi8 263 11 Biomedical Biomedical NNP cord-310304-f28tjmi8 263 12 Literature Literature NNP cord-310304-f28tjmi8 263 13 Clinical clinical JJ cord-310304-f28tjmi8 263 14 features feature NNS cord-310304-f28tjmi8 263 15 of of IN cord-310304-f28tjmi8 263 16 patients patient NNS cord-310304-f28tjmi8 263 17 infected infect VBN cord-310304-f28tjmi8 263 18 with with IN cord-310304-f28tjmi8 263 19 2019 2019 CD cord-310304-f28tjmi8 263 20 novel novel JJ cord-310304-f28tjmi8 263 21 coronavirus coronavirus NN cord-310304-f28tjmi8 263 22 in in IN cord-310304-f28tjmi8 263 23 Wuhan Wuhan NNP cord-310304-f28tjmi8 263 24 Discovery Discovery NNP cord-310304-f28tjmi8 263 25 of of IN cord-310304-f28tjmi8 263 26 Seven Seven NNP cord-310304-f28tjmi8 263 27 Novel Novel NNP cord-310304-f28tjmi8 263 28 Mammalian mammalian JJ cord-310304-f28tjmi8 263 29 and and CC cord-310304-f28tjmi8 263 30 Avian Avian NNP cord-310304-f28tjmi8 263 31 Coronaviruses Coronaviruses NNPS cord-310304-f28tjmi8 263 32 in in IN cord-310304-f28tjmi8 263 33 the the DT cord-310304-f28tjmi8 263 34 Genus Genus NNP cord-310304-f28tjmi8 263 35 Deltacoronavirus Deltacoronavirus NNP cord-310304-f28tjmi8 263 36 Supports support VBZ cord-310304-f28tjmi8 263 37 Bat Bat NNP cord-310304-f28tjmi8 263 38 Coronaviruses Coronaviruses NNPS cord-310304-f28tjmi8 263 39 as as IN cord-310304-f28tjmi8 263 40 the the DT cord-310304-f28tjmi8 263 41 Gene Gene NNP cord-310304-f28tjmi8 263 42 Source Source NNP cord-310304-f28tjmi8 263 43 of of IN cord-310304-f28tjmi8 263 44 Alphacoronavirus Alphacoronavirus NNP cord-310304-f28tjmi8 263 45 and and CC cord-310304-f28tjmi8 263 46 Betacoronavirus Betacoronavirus NNP cord-310304-f28tjmi8 263 47 and and CC cord-310304-f28tjmi8 263 48 Avian Avian NNP cord-310304-f28tjmi8 263 49 Coronaviruses Coronaviruses NNP cord-310304-f28tjmi8 263 50 as as IN cord-310304-f28tjmi8 263 51 the the DT cord-310304-f28tjmi8 263 52 Gene Gene NNP cord-310304-f28tjmi8 263 53 Source Source NNP cord-310304-f28tjmi8 263 54 of of IN cord-310304-f28tjmi8 263 55 Gammacoronavirus Gammacoronavirus NNP cord-310304-f28tjmi8 263 56 and and CC cord-310304-f28tjmi8 263 57 Deltacoronavirus Deltacoronavirus NNP cord-310304-f28tjmi8 263 58 Committee Committee NNP cord-310304-f28tjmi8 263 59 on on IN cord-310304-f28tjmi8 263 60 Taxonomy Taxonomy NNP cord-310304-f28tjmi8 263 61 of of IN cord-310304-f28tjmi8 263 62 Viruses Viruses NNPS cord-310304-f28tjmi8 263 63 . . . cord-310304-f28tjmi8 264 1 Virus Virus NNP cord-310304-f28tjmi8 264 2 Taxonomy Taxonomy NNP cord-310304-f28tjmi8 264 3 Outbreak outbreak NN cord-310304-f28tjmi8 264 4 of of IN cord-310304-f28tjmi8 264 5 a a DT cord-310304-f28tjmi8 264 6 novel novel JJ cord-310304-f28tjmi8 264 7 coronavirus coronavirus NN cord-310304-f28tjmi8 265 1 The the DT cord-310304-f28tjmi8 265 2 epidemiology epidemiology NN cord-310304-f28tjmi8 265 3 and and CC cord-310304-f28tjmi8 265 4 pathogenesis pathogenesis NN cord-310304-f28tjmi8 265 5 of of IN cord-310304-f28tjmi8 265 6 coronavirus coronavirus NN cord-310304-f28tjmi8 265 7 disease disease NN cord-310304-f28tjmi8 265 8 ( ( -LRB- cord-310304-f28tjmi8 265 9 COVID-19 covid-19 VB cord-310304-f28tjmi8 265 10 ) ) -RRB- cord-310304-f28tjmi8 265 11 outbreak outbreak NN cord-310304-f28tjmi8 265 12 Interspecies Interspecies NNP cord-310304-f28tjmi8 265 13 transmission transmission NN cord-310304-f28tjmi8 265 14 and and CC cord-310304-f28tjmi8 265 15 emergence emergence NN cord-310304-f28tjmi8 265 16 of of IN cord-310304-f28tjmi8 265 17 novel novel JJ cord-310304-f28tjmi8 265 18 viruses virus NNS cord-310304-f28tjmi8 265 19 : : : cord-310304-f28tjmi8 266 1 Lessons lesson NNS cord-310304-f28tjmi8 266 2 from from IN cord-310304-f28tjmi8 266 3 bats bat NNS cord-310304-f28tjmi8 266 4 and and CC cord-310304-f28tjmi8 266 5 birds bird NNS cord-310304-f28tjmi8 267 1 The the DT cord-310304-f28tjmi8 267 2 continuing continue VBG cord-310304-f28tjmi8 267 3 2019-nCoV 2019-ncov CD cord-310304-f28tjmi8 267 4 epidemic epidemic NN cord-310304-f28tjmi8 267 5 threat threat NN cord-310304-f28tjmi8 267 6 of of IN cord-310304-f28tjmi8 267 7 novel novel JJ cord-310304-f28tjmi8 267 8 coronaviruses coronaviruse NNS cord-310304-f28tjmi8 267 9 to to IN cord-310304-f28tjmi8 267 10 global global JJ cord-310304-f28tjmi8 267 11 health health NN cord-310304-f28tjmi8 267 12 - - , cord-310304-f28tjmi8 267 13 The the DT cord-310304-f28tjmi8 267 14 latest late JJS cord-310304-f28tjmi8 267 15 2019 2019 CD cord-310304-f28tjmi8 267 16 novel novel JJ cord-310304-f28tjmi8 267 17 coronavirus coronavirus NN cord-310304-f28tjmi8 267 18 outbreak outbreak NN cord-310304-f28tjmi8 267 19 in in IN cord-310304-f28tjmi8 267 20 Wuhan Wuhan NNP cord-310304-f28tjmi8 268 1 An an DT cord-310304-f28tjmi8 268 2 Overview Overview NNP cord-310304-f28tjmi8 268 3 of of IN cord-310304-f28tjmi8 268 4 Their -PRON- PRP$ cord-310304-f28tjmi8 268 5 Replication Replication NNP cord-310304-f28tjmi8 268 6 and and CC cord-310304-f28tjmi8 268 7 Pathogenesis Pathogenesis NNP cord-310304-f28tjmi8 268 8 Coronavirus Coronavirus NNP cord-310304-f28tjmi8 268 9 Pathogenesis Pathogenesis NNP cord-310304-f28tjmi8 268 10 and and CC cord-310304-f28tjmi8 268 11 the the DT cord-310304-f28tjmi8 268 12 Emerging Emerging NNP cord-310304-f28tjmi8 268 13 Pathogen Pathogen NNP cord-310304-f28tjmi8 268 14 Severe Severe NNP cord-310304-f28tjmi8 268 15 Acute acute JJ cord-310304-f28tjmi8 268 16 Respiratory Respiratory NNP cord-310304-f28tjmi8 268 17 Syndrome Syndrome NNP cord-310304-f28tjmi8 268 18 Functional functional JJ cord-310304-f28tjmi8 268 19 assessment assessment NN cord-310304-f28tjmi8 268 20 of of IN cord-310304-f28tjmi8 268 21 cell cell NN cord-310304-f28tjmi8 268 22 entry entry NN cord-310304-f28tjmi8 268 23 and and CC cord-310304-f28tjmi8 268 24 receptor receptor NN cord-310304-f28tjmi8 268 25 usage usage NN cord-310304-f28tjmi8 268 26 for for IN cord-310304-f28tjmi8 268 27 SARS SARS NNP cord-310304-f28tjmi8 268 28 - - HYPH cord-310304-f28tjmi8 268 29 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 268 30 and and CC cord-310304-f28tjmi8 268 31 other other JJ cord-310304-f28tjmi8 268 32 lineage lineage NN cord-310304-f28tjmi8 268 33 B b NN cord-310304-f28tjmi8 268 34 betacoronaviruses betacoronaviruses NNP cord-310304-f28tjmi8 268 35 Characterization Characterization NNP cord-310304-f28tjmi8 268 36 and and CC cord-310304-f28tjmi8 268 37 Complete Complete NNP cord-310304-f28tjmi8 268 38 Genome Genome NNP cord-310304-f28tjmi8 268 39 Sequence sequence NN cord-310304-f28tjmi8 268 40 of of IN cord-310304-f28tjmi8 268 41 a a DT cord-310304-f28tjmi8 268 42 Novel Novel NNP cord-310304-f28tjmi8 268 43 Coronavirus Coronavirus NNP cord-310304-f28tjmi8 268 44 , , , cord-310304-f28tjmi8 268 45 Coronavirus Coronavirus NNP cord-310304-f28tjmi8 268 46 HKU1 HKU1 NNP cord-310304-f28tjmi8 268 47 , , , cord-310304-f28tjmi8 268 48 from from IN cord-310304-f28tjmi8 268 49 Patients patient NNS cord-310304-f28tjmi8 268 50 with with IN cord-310304-f28tjmi8 268 51 Pneumonia Pneumonia NNP cord-310304-f28tjmi8 268 52 Middle Middle NNP cord-310304-f28tjmi8 268 53 East East NNP cord-310304-f28tjmi8 268 54 Respiratory Respiratory NNP cord-310304-f28tjmi8 268 55 Syndrome Syndrome NNP cord-310304-f28tjmi8 268 56 Coronavirus Coronavirus NNP cord-310304-f28tjmi8 268 57 : : : cord-310304-f28tjmi8 269 1 Another another DT cord-310304-f28tjmi8 269 2 Zoonotic Zoonotic NNP cord-310304-f28tjmi8 269 3 Betacoronavirus Betacoronavirus NNP cord-310304-f28tjmi8 270 1 Causing cause VBG cord-310304-f28tjmi8 270 2 SARS SARS NNP cord-310304-f28tjmi8 270 3 - - HYPH cord-310304-f28tjmi8 270 4 Like Like NNP cord-310304-f28tjmi8 270 5 Disease Disease NNP cord-310304-f28tjmi8 270 6 Severe Severe NNP cord-310304-f28tjmi8 270 7 Acute acute JJ cord-310304-f28tjmi8 270 8 Respiratory Respiratory NNP cord-310304-f28tjmi8 270 9 Syndrome Syndrome NNP cord-310304-f28tjmi8 270 10 Coronavirus Coronavirus NNP cord-310304-f28tjmi8 270 11 as as IN cord-310304-f28tjmi8 270 12 an an DT cord-310304-f28tjmi8 270 13 Agent Agent NNP cord-310304-f28tjmi8 270 14 of of IN cord-310304-f28tjmi8 270 15 Emerging Emerging NNP cord-310304-f28tjmi8 270 16 and and CC cord-310304-f28tjmi8 270 17 Reemerging reemerge VBG cord-310304-f28tjmi8 270 18 Infection infection NN cord-310304-f28tjmi8 270 19 Epidemiology epidemiology NN cord-310304-f28tjmi8 270 20 and and CC cord-310304-f28tjmi8 270 21 cause cause NN cord-310304-f28tjmi8 270 22 of of IN cord-310304-f28tjmi8 270 23 severe severe JJ cord-310304-f28tjmi8 270 24 acute acute JJ cord-310304-f28tjmi8 270 25 respiratory respiratory JJ cord-310304-f28tjmi8 270 26 syndrome syndrome NN cord-310304-f28tjmi8 270 27 ( ( -LRB- cord-310304-f28tjmi8 270 28 SARS SARS NNP cord-310304-f28tjmi8 270 29 ) ) -RRB- cord-310304-f28tjmi8 270 30 in in IN cord-310304-f28tjmi8 270 31 Guangdong Guangdong NNP cord-310304-f28tjmi8 270 32 , , , cord-310304-f28tjmi8 270 33 People People NNPS cord-310304-f28tjmi8 270 34 's 's POS cord-310304-f28tjmi8 270 35 Republic Republic NNP cord-310304-f28tjmi8 270 36 of of IN cord-310304-f28tjmi8 270 37 China China NNP cord-310304-f28tjmi8 270 38 Newly newly RB cord-310304-f28tjmi8 270 39 discovered discover VBD cord-310304-f28tjmi8 270 40 coronavirus coronavirus NN cord-310304-f28tjmi8 270 41 as as IN cord-310304-f28tjmi8 270 42 the the DT cord-310304-f28tjmi8 270 43 primary primary JJ cord-310304-f28tjmi8 270 44 cause cause NN cord-310304-f28tjmi8 270 45 of of IN cord-310304-f28tjmi8 270 46 severe severe JJ cord-310304-f28tjmi8 270 47 acute acute JJ cord-310304-f28tjmi8 270 48 respiratory respiratory JJ cord-310304-f28tjmi8 270 49 syndrome syndrome NN cord-310304-f28tjmi8 270 50 Isolation isolation NN cord-310304-f28tjmi8 270 51 of of IN cord-310304-f28tjmi8 270 52 a a DT cord-310304-f28tjmi8 270 53 Novel Novel NNP cord-310304-f28tjmi8 270 54 Coronavirus Coronavirus NNP cord-310304-f28tjmi8 270 55 from from IN cord-310304-f28tjmi8 270 56 a a DT cord-310304-f28tjmi8 270 57 Man man NN cord-310304-f28tjmi8 270 58 with with IN cord-310304-f28tjmi8 270 59 Pneumonia Pneumonia NNP cord-310304-f28tjmi8 270 60 in in IN cord-310304-f28tjmi8 270 61 Saudi Saudi NNP cord-310304-f28tjmi8 270 62 Arabia Arabia NNP cord-310304-f28tjmi8 270 63 Genomic Genomic NNP cord-310304-f28tjmi8 270 64 Characterization characterization NN cord-310304-f28tjmi8 270 65 of of IN cord-310304-f28tjmi8 270 66 a a DT cord-310304-f28tjmi8 270 67 Newly newly RB cord-310304-f28tjmi8 270 68 Discovered discover VBN cord-310304-f28tjmi8 270 69 Coronavirus Coronavirus NNP cord-310304-f28tjmi8 270 70 Associated Associated NNP cord-310304-f28tjmi8 270 71 with with IN cord-310304-f28tjmi8 270 72 Acute acute JJ cord-310304-f28tjmi8 270 73 Respiratory respiratory JJ cord-310304-f28tjmi8 270 74 Distress Distress NNP cord-310304-f28tjmi8 270 75 Syndrome Syndrome NNP cord-310304-f28tjmi8 270 76 in in IN cord-310304-f28tjmi8 270 77 Humans human NNS cord-310304-f28tjmi8 271 1 The the DT cord-310304-f28tjmi8 271 2 novel novel JJ cord-310304-f28tjmi8 271 3 coronavirus coronavirus NN cord-310304-f28tjmi8 271 4 SARS SARS NNP cord-310304-f28tjmi8 271 5 - - HYPH cord-310304-f28tjmi8 271 6 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 271 7 : : : cord-310304-f28tjmi8 271 8 From from IN cord-310304-f28tjmi8 271 9 a a DT cord-310304-f28tjmi8 271 10 zoonotic zoonotic JJ cord-310304-f28tjmi8 271 11 infection infection NN cord-310304-f28tjmi8 271 12 to to IN cord-310304-f28tjmi8 271 13 coronavirus coronavirus NN cord-310304-f28tjmi8 271 14 disease disease NN cord-310304-f28tjmi8 271 15 2019 2019 CD cord-310304-f28tjmi8 271 16 Probable probable JJ cord-310304-f28tjmi8 271 17 Pangolin Pangolin NNP cord-310304-f28tjmi8 271 18 Origin Origin NNP cord-310304-f28tjmi8 271 19 of of IN cord-310304-f28tjmi8 271 20 SARS SARS NNP cord-310304-f28tjmi8 271 21 - - HYPH cord-310304-f28tjmi8 271 22 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 272 1 Associated associate VBN cord-310304-f28tjmi8 272 2 with with IN cord-310304-f28tjmi8 272 3 the the DT cord-310304-f28tjmi8 272 4 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 272 5 Outbreak Outbreak NNP cord-310304-f28tjmi8 272 6 Covid-19 Covid-19 NNP cord-310304-f28tjmi8 272 7 : : : cord-310304-f28tjmi8 272 8 Risk risk NN cord-310304-f28tjmi8 272 9 factors factor NNS cord-310304-f28tjmi8 272 10 for for IN cord-310304-f28tjmi8 272 11 severe severe JJ cord-310304-f28tjmi8 272 12 disease disease NN cord-310304-f28tjmi8 272 13 and and CC cord-310304-f28tjmi8 272 14 death death NN cord-310304-f28tjmi8 272 15 Guidance guidance NN cord-310304-f28tjmi8 272 16 on on IN cord-310304-f28tjmi8 272 17 Social Social NNP cord-310304-f28tjmi8 272 18 Distancing Distancing NNP cord-310304-f28tjmi8 272 19 for for IN cord-310304-f28tjmi8 272 20 Everyone everyone NN cord-310304-f28tjmi8 272 21 in in IN cord-310304-f28tjmi8 272 22 the the DT cord-310304-f28tjmi8 272 23 UK UK NNP cord-310304-f28tjmi8 272 24 . . . cord-310304-f28tjmi8 273 1 2020 2020 CD cord-310304-f28tjmi8 273 2 . . . cord-310304-f28tjmi8 274 1 Available available JJ cord-310304-f28tjmi8 274 2 online online JJ cord-310304-f28tjmi8 274 3 Population population NN cord-310304-f28tjmi8 274 4 - - HYPH cord-310304-f28tjmi8 274 5 based base VBN cord-310304-f28tjmi8 274 6 estimates estimate NNS cord-310304-f28tjmi8 274 7 of of IN cord-310304-f28tjmi8 274 8 chronic chronic JJ cord-310304-f28tjmi8 274 9 conditions condition NNS cord-310304-f28tjmi8 274 10 affecting affect VBG cord-310304-f28tjmi8 274 11 risk risk NN cord-310304-f28tjmi8 274 12 for for IN cord-310304-f28tjmi8 274 13 complications complication NNS cord-310304-f28tjmi8 274 14 from from IN cord-310304-f28tjmi8 274 15 coronavirus coronavirus NN cord-310304-f28tjmi8 274 16 disease disease NN cord-310304-f28tjmi8 274 17 , , , cord-310304-f28tjmi8 274 18 United United NNP cord-310304-f28tjmi8 274 19 States States NNP cord-310304-f28tjmi8 274 20 Clinical clinical JJ cord-310304-f28tjmi8 274 21 characteristics characteristic NNS cord-310304-f28tjmi8 274 22 of of IN cord-310304-f28tjmi8 274 23 113 113 CD cord-310304-f28tjmi8 274 24 deceased deceased JJ cord-310304-f28tjmi8 274 25 patients patient NNS cord-310304-f28tjmi8 274 26 with with IN cord-310304-f28tjmi8 274 27 coronavirus coronavirus NN cord-310304-f28tjmi8 274 28 disease disease NN cord-310304-f28tjmi8 274 29 2019 2019 CD cord-310304-f28tjmi8 274 30 : : : cord-310304-f28tjmi8 275 1 Retrospective retrospective JJ cord-310304-f28tjmi8 275 2 study study NN cord-310304-f28tjmi8 275 3 Chicago Chicago NNP cord-310304-f28tjmi8 275 4 's 's POS cord-310304-f28tjmi8 275 5 Coronavirus Coronavirus NNP cord-310304-f28tjmi8 275 6 Disparity Disparity NNP cord-310304-f28tjmi8 276 1 : : : cord-310304-f28tjmi8 276 2 Black black JJ cord-310304-f28tjmi8 276 3 Chicagoans Chicagoans NNPS cord-310304-f28tjmi8 276 4 are be VBP cord-310304-f28tjmi8 276 5 Dying die VBG cord-310304-f28tjmi8 276 6 at at IN cord-310304-f28tjmi8 276 7 Nearly nearly RB cord-310304-f28tjmi8 276 8 Six six CD cord-310304-f28tjmi8 276 9 Times time NNS cord-310304-f28tjmi8 276 10 the the DT cord-310304-f28tjmi8 276 11 Rate rate NN cord-310304-f28tjmi8 276 12 of of IN cord-310304-f28tjmi8 276 13 White White NNP cord-310304-f28tjmi8 276 14 Residents Residents NNPS cord-310304-f28tjmi8 276 15 , , , cord-310304-f28tjmi8 276 16 Data Data NNP cord-310304-f28tjmi8 276 17 Show Show NNP cord-310304-f28tjmi8 276 18 . . . cord-310304-f28tjmi8 277 1 Chicago Chicago NNP cord-310304-f28tjmi8 277 2 Tribune Tribune NNP cord-310304-f28tjmi8 278 1 The the DT cord-310304-f28tjmi8 278 2 Coronavirus Coronavirus NNP cord-310304-f28tjmi8 278 3 is be VBZ cord-310304-f28tjmi8 278 4 Infecting infect VBG cord-310304-f28tjmi8 278 5 and and CC cord-310304-f28tjmi8 278 6 Killing kill VBG cord-310304-f28tjmi8 278 7 Black Black NNP cord-310304-f28tjmi8 278 8 Americans Americans NNPS cord-310304-f28tjmi8 278 9 at at IN cord-310304-f28tjmi8 278 10 an an DT cord-310304-f28tjmi8 278 11 Alarmingly alarmingly RB cord-310304-f28tjmi8 278 12 High high JJ cord-310304-f28tjmi8 278 13 Rate rate NN cord-310304-f28tjmi8 278 14 Virus virus NN cord-310304-f28tjmi8 278 15 Hits hit VBZ cord-310304-f28tjmi8 278 16 Blacks black NNS cord-310304-f28tjmi8 278 17 , , , cord-310304-f28tjmi8 278 18 People People NNS cord-310304-f28tjmi8 278 19 with with IN cord-310304-f28tjmi8 278 20 Hypertension Hypertension NNP cord-310304-f28tjmi8 278 21 New New NNP cord-310304-f28tjmi8 278 22 York York NNP cord-310304-f28tjmi8 278 23 State State NNP cord-310304-f28tjmi8 278 24 Department Department NNP cord-310304-f28tjmi8 278 25 of of IN cord-310304-f28tjmi8 278 26 Health Health NNP cord-310304-f28tjmi8 278 27 . . . cord-310304-f28tjmi8 279 1 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 279 2 Fatalities Fatalities NNP cord-310304-f28tjmi8 279 3 gov gov NNP cord-310304-f28tjmi8 279 4 / / SYM cord-310304-f28tjmi8 279 5 views view NNS cord-310304-f28tjmi8 279 6 / / SYM cord-310304-f28tjmi8 279 7 NYS NYS NNP cord-310304-f28tjmi8 279 8 - - HYPH cord-310304-f28tjmi8 279 9 COVID19-Tracker COVID19-Tracker NNP cord-310304-f28tjmi8 280 1 /NYSDOHCOVID-19Tracker /nysdohcovid-19tracker LS cord-310304-f28tjmi8 280 2 - - : cord-310304-f28tjmi8 280 3 Fatalities fatality NNS cord-310304-f28tjmi8 280 4 ? ? . cord-310304-f28tjmi8 281 1 % % NN cord-310304-f28tjmi8 282 1 3Aembed 3aembed JJ cord-310304-f28tjmi8 282 2 = = SYM cord-310304-f28tjmi8 282 3 yes&%3Atoolbar= yes&%3Atoolbar= NNS cord-310304-f28tjmi8 283 1 no&%3Atabs no&%3atabs NN cord-310304-f28tjmi8 283 2 = = SYM cord-310304-f28tjmi8 283 3 n n NNP cord-310304-f28tjmi8 283 4 ( ( -LRB- cord-310304-f28tjmi8 283 5 accessed access VBN cord-310304-f28tjmi8 283 6 on on IN cord-310304-f28tjmi8 283 7 1 1 CD cord-310304-f28tjmi8 283 8 Association Association NNP cord-310304-f28tjmi8 283 9 of of IN cord-310304-f28tjmi8 283 10 Public Public NNP cord-310304-f28tjmi8 283 11 Health Health NNP cord-310304-f28tjmi8 283 12 Interventions Interventions NNPS cord-310304-f28tjmi8 283 13 With with IN cord-310304-f28tjmi8 283 14 the the DT cord-310304-f28tjmi8 283 15 Epidemiology Epidemiology NNP cord-310304-f28tjmi8 283 16 of of IN cord-310304-f28tjmi8 283 17 the the DT cord-310304-f28tjmi8 283 18 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 283 19 Outbreak Outbreak NNP cord-310304-f28tjmi8 283 20 in in IN cord-310304-f28tjmi8 283 21 Wuhan Wuhan NNP cord-310304-f28tjmi8 283 22 , , , cord-310304-f28tjmi8 283 23 China China NNP cord-310304-f28tjmi8 283 24 Differences Differences NNPS cord-310304-f28tjmi8 283 25 in in IN cord-310304-f28tjmi8 283 26 diabetes diabetes NN cord-310304-f28tjmi8 283 27 prevalence prevalence NN cord-310304-f28tjmi8 283 28 , , , cord-310304-f28tjmi8 283 29 incidence incidence NN cord-310304-f28tjmi8 283 30 , , , cord-310304-f28tjmi8 283 31 and and CC cord-310304-f28tjmi8 283 32 mortality mortality NN cord-310304-f28tjmi8 283 33 among among IN cord-310304-f28tjmi8 283 34 the the DT cord-310304-f28tjmi8 283 35 elderly elderly JJ cord-310304-f28tjmi8 283 36 of of IN cord-310304-f28tjmi8 283 37 four four CD cord-310304-f28tjmi8 283 38 racial racial JJ cord-310304-f28tjmi8 283 39 / / SYM cord-310304-f28tjmi8 283 40 ethnic ethnic JJ cord-310304-f28tjmi8 283 41 groups group NNS cord-310304-f28tjmi8 283 42 : : : cord-310304-f28tjmi8 283 43 Whites white NNS cord-310304-f28tjmi8 283 44 , , , cord-310304-f28tjmi8 283 45 blacks black NNS cord-310304-f28tjmi8 283 46 , , , cord-310304-f28tjmi8 283 47 hispanics hispanics NNPS cord-310304-f28tjmi8 283 48 , , , cord-310304-f28tjmi8 283 49 and and CC cord-310304-f28tjmi8 283 50 asians asians NNPS cord-310304-f28tjmi8 284 1 The the DT cord-310304-f28tjmi8 284 2 continuing continue VBG cord-310304-f28tjmi8 284 3 epidemics epidemic NNS cord-310304-f28tjmi8 284 4 of of IN cord-310304-f28tjmi8 284 5 obesity obesity NN cord-310304-f28tjmi8 284 6 and and CC cord-310304-f28tjmi8 284 7 diabetes diabetes NN cord-310304-f28tjmi8 284 8 in in IN cord-310304-f28tjmi8 284 9 the the DT cord-310304-f28tjmi8 284 10 United United NNP cord-310304-f28tjmi8 284 11 States States NNP cord-310304-f28tjmi8 284 12 Social Social NNP cord-310304-f28tjmi8 284 13 Determinants Determinants NNPS cord-310304-f28tjmi8 284 14 of of IN cord-310304-f28tjmi8 284 15 Health Health NNP cord-310304-f28tjmi8 284 16 and and CC cord-310304-f28tjmi8 284 17 Racial Racial NNP cord-310304-f28tjmi8 284 18 / / SYM cord-310304-f28tjmi8 284 19 Ethnic ethnic JJ cord-310304-f28tjmi8 284 20 Disparities Disparities NNPS cord-310304-f28tjmi8 284 21 in in IN cord-310304-f28tjmi8 284 22 Type type NN cord-310304-f28tjmi8 284 23 2 2 CD cord-310304-f28tjmi8 284 24 Diabetes diabetes NN cord-310304-f28tjmi8 284 25 in in IN cord-310304-f28tjmi8 284 26 Youth Youth NNP cord-310304-f28tjmi8 284 27 Acute Acute NNP cord-310304-f28tjmi8 284 28 and and CC cord-310304-f28tjmi8 284 29 chronic chronic JJ cord-310304-f28tjmi8 284 30 complications complication NNS cord-310304-f28tjmi8 284 31 of of IN cord-310304-f28tjmi8 284 32 type type NN cord-310304-f28tjmi8 284 33 2 2 CD cord-310304-f28tjmi8 284 34 diabetes diabetes NN cord-310304-f28tjmi8 284 35 mellitus mellitus NN cord-310304-f28tjmi8 284 36 in in IN cord-310304-f28tjmi8 284 37 children child NNS cord-310304-f28tjmi8 284 38 and and CC cord-310304-f28tjmi8 284 39 adolescents adolescent NNS cord-310304-f28tjmi8 284 40 Presentation Presentation NNP cord-310304-f28tjmi8 284 41 of of IN cord-310304-f28tjmi8 284 42 youth youth NN cord-310304-f28tjmi8 284 43 with with IN cord-310304-f28tjmi8 284 44 type type NN cord-310304-f28tjmi8 284 45 2 2 CD cord-310304-f28tjmi8 284 46 diabetes diabete NNS cord-310304-f28tjmi8 284 47 in in IN cord-310304-f28tjmi8 284 48 the the DT cord-310304-f28tjmi8 284 49 Pediatric Pediatric NNP cord-310304-f28tjmi8 284 50 Diabetes Diabetes NNP cord-310304-f28tjmi8 284 51 Consortium Consortium NNP cord-310304-f28tjmi8 284 52 Letter Letter NNP cord-310304-f28tjmi8 284 53 to to IN cord-310304-f28tjmi8 284 54 the the DT cord-310304-f28tjmi8 284 55 Editor Editor NNP cord-310304-f28tjmi8 284 56 : : : cord-310304-f28tjmi8 284 57 COVID-19 covid-19 VB cord-310304-f28tjmi8 284 58 in in IN cord-310304-f28tjmi8 284 59 patients patient NNS cord-310304-f28tjmi8 284 60 with with IN cord-310304-f28tjmi8 284 61 diabetes diabetes NN cord-310304-f28tjmi8 284 62 : : : cord-310304-f28tjmi8 284 63 Risk risk NN cord-310304-f28tjmi8 284 64 factors factor NNS cord-310304-f28tjmi8 284 65 that that WDT cord-310304-f28tjmi8 284 66 increase increase VBP cord-310304-f28tjmi8 284 67 morbidity morbidity NN cord-310304-f28tjmi8 284 68 Commentary commentary NN cord-310304-f28tjmi8 284 69 : : : cord-310304-f28tjmi8 284 70 COVID-19 covid-19 VB cord-310304-f28tjmi8 284 71 in in IN cord-310304-f28tjmi8 284 72 patients patient NNS cord-310304-f28tjmi8 284 73 with with IN cord-310304-f28tjmi8 284 74 diabetes diabetes NN cord-310304-f28tjmi8 284 75 Plasma plasma NN cord-310304-f28tjmi8 284 76 glucose glucose NN cord-310304-f28tjmi8 284 77 levels level NNS cord-310304-f28tjmi8 284 78 and and CC cord-310304-f28tjmi8 284 79 diabetes diabetes NN cord-310304-f28tjmi8 284 80 are be VBP cord-310304-f28tjmi8 284 81 independent independent JJ cord-310304-f28tjmi8 284 82 predictors predictor NNS cord-310304-f28tjmi8 284 83 for for IN cord-310304-f28tjmi8 284 84 mortality mortality NN cord-310304-f28tjmi8 284 85 and and CC cord-310304-f28tjmi8 284 86 morbidity morbidity NN cord-310304-f28tjmi8 284 87 in in IN cord-310304-f28tjmi8 284 88 patients patient NNS cord-310304-f28tjmi8 284 89 with with IN cord-310304-f28tjmi8 284 90 SARS SARS NNP cord-310304-f28tjmi8 284 91 B B NNP cord-310304-f28tjmi8 284 92 cells cell NNS cord-310304-f28tjmi8 284 93 of of IN cord-310304-f28tjmi8 284 94 multiple multiple JJ cord-310304-f28tjmi8 284 95 sclerosis sclerosis NN cord-310304-f28tjmi8 284 96 patients patient NNS cord-310304-f28tjmi8 284 97 induce induce VBP cord-310304-f28tjmi8 284 98 autoreactive autoreactive JJ cord-310304-f28tjmi8 284 99 proinflammatory proinflammatory JJ cord-310304-f28tjmi8 284 100 T t NN cord-310304-f28tjmi8 284 101 cell cell NN cord-310304-f28tjmi8 284 102 responses response NNS cord-310304-f28tjmi8 285 1 A a DT cord-310304-f28tjmi8 285 2 Global Global NNP cord-310304-f28tjmi8 285 3 Brief Brief NNP cord-310304-f28tjmi8 285 4 on on IN cord-310304-f28tjmi8 285 5 Hypertension hypertension NN cord-310304-f28tjmi8 286 1 The the DT cord-310304-f28tjmi8 286 2 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 286 3 Pandemic Pandemic NNP cord-310304-f28tjmi8 286 4 : : : cord-310304-f28tjmi8 287 1 A a DT cord-310304-f28tjmi8 287 2 Call call NN cord-310304-f28tjmi8 287 3 to to IN cord-310304-f28tjmi8 287 4 Action action NN cord-310304-f28tjmi8 287 5 to to TO cord-310304-f28tjmi8 287 6 Identify identify VB cord-310304-f28tjmi8 287 7 and and CC cord-310304-f28tjmi8 287 8 Address address VB cord-310304-f28tjmi8 287 9 Racial Racial NNP cord-310304-f28tjmi8 287 10 and and CC cord-310304-f28tjmi8 287 11 Ethnic ethnic JJ cord-310304-f28tjmi8 287 12 Disparities Disparities NNPS cord-310304-f28tjmi8 287 13 Clinical clinical JJ cord-310304-f28tjmi8 287 14 course course NN cord-310304-f28tjmi8 287 15 and and CC cord-310304-f28tjmi8 287 16 risk risk NN cord-310304-f28tjmi8 287 17 factors factor NNS cord-310304-f28tjmi8 287 18 for for IN cord-310304-f28tjmi8 287 19 mortality mortality NN cord-310304-f28tjmi8 287 20 of of IN cord-310304-f28tjmi8 287 21 adult adult NN cord-310304-f28tjmi8 287 22 inpatients inpatient NNS cord-310304-f28tjmi8 287 23 with with IN cord-310304-f28tjmi8 287 24 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 287 25 in in IN cord-310304-f28tjmi8 287 26 Wuhan Wuhan NNP cord-310304-f28tjmi8 287 27 , , , cord-310304-f28tjmi8 287 28 China China NNP cord-310304-f28tjmi8 287 29 : : : cord-310304-f28tjmi8 288 1 A a DT cord-310304-f28tjmi8 288 2 retrospective retrospective JJ cord-310304-f28tjmi8 288 3 cohort cohort NN cord-310304-f28tjmi8 288 4 study study NN cord-310304-f28tjmi8 288 5 Risk Risk NNP cord-310304-f28tjmi8 288 6 Factors Factors NNP cord-310304-f28tjmi8 288 7 Associated Associated NNP cord-310304-f28tjmi8 288 8 with with IN cord-310304-f28tjmi8 288 9 Acute acute JJ cord-310304-f28tjmi8 288 10 Respiratory Respiratory NNP cord-310304-f28tjmi8 288 11 Distress Distress NNP cord-310304-f28tjmi8 288 12 Syndrome Syndrome NNP cord-310304-f28tjmi8 288 13 and and CC cord-310304-f28tjmi8 288 14 Death death NN cord-310304-f28tjmi8 288 15 in in IN cord-310304-f28tjmi8 288 16 Patients Patients NNP cord-310304-f28tjmi8 288 17 with with IN cord-310304-f28tjmi8 288 18 Coronavirus Coronavirus NNP cord-310304-f28tjmi8 288 19 Disease Disease NNP cord-310304-f28tjmi8 288 20 Receptor Receptor NNP cord-310304-f28tjmi8 288 21 Recognition Recognition NNP cord-310304-f28tjmi8 288 22 by by IN cord-310304-f28tjmi8 288 23 the the DT cord-310304-f28tjmi8 288 24 Novel Novel NNP cord-310304-f28tjmi8 288 25 Coronavirus Coronavirus NNP cord-310304-f28tjmi8 288 26 from from IN cord-310304-f28tjmi8 288 27 Wuhan Wuhan NNP cord-310304-f28tjmi8 288 28 : : : cord-310304-f28tjmi8 289 1 An an DT cord-310304-f28tjmi8 289 2 Analysis Analysis NNP cord-310304-f28tjmi8 289 3 Based base VBN cord-310304-f28tjmi8 289 4 on on IN cord-310304-f28tjmi8 289 5 Decade decade NN cord-310304-f28tjmi8 289 6 - - HYPH cord-310304-f28tjmi8 289 7 Long Long NNP cord-310304-f28tjmi8 289 8 Structural Structural NNP cord-310304-f28tjmi8 289 9 Studies Studies NNPS cord-310304-f28tjmi8 289 10 of of IN cord-310304-f28tjmi8 289 11 SARS SARS NNP cord-310304-f28tjmi8 289 12 Coronavirus Coronavirus NNP cord-310304-f28tjmi8 289 13 SARS SARS NNP cord-310304-f28tjmi8 289 14 - - HYPH cord-310304-f28tjmi8 289 15 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 289 16 Cell Cell NNP cord-310304-f28tjmi8 289 17 Entry entry NN cord-310304-f28tjmi8 289 18 Depends depend VBZ cord-310304-f28tjmi8 289 19 on on IN cord-310304-f28tjmi8 289 20 ACE2 ACE2 NNP cord-310304-f28tjmi8 289 21 and and CC cord-310304-f28tjmi8 289 22 TMPRSS2 TMPRSS2 NNP cord-310304-f28tjmi8 289 23 and and CC cord-310304-f28tjmi8 289 24 Is be VBZ cord-310304-f28tjmi8 289 25 Blocked block VBN cord-310304-f28tjmi8 289 26 by by IN cord-310304-f28tjmi8 290 1 a a DT cord-310304-f28tjmi8 290 2 Clinically Clinically NNP cord-310304-f28tjmi8 290 3 Proven prove VBN cord-310304-f28tjmi8 290 4 Protease protease NN cord-310304-f28tjmi8 290 5 Inhibitor Inhibitor NNP cord-310304-f28tjmi8 290 6 Angiotensin Angiotensin NNP cord-310304-f28tjmi8 290 7 - - HYPH cord-310304-f28tjmi8 290 8 converting convert VBG cord-310304-f28tjmi8 290 9 enzyme enzyme NN cord-310304-f28tjmi8 290 10 2 2 CD cord-310304-f28tjmi8 290 11 protects protect VBZ cord-310304-f28tjmi8 290 12 from from IN cord-310304-f28tjmi8 290 13 severe severe JJ cord-310304-f28tjmi8 290 14 acute acute JJ cord-310304-f28tjmi8 290 15 lung lung NN cord-310304-f28tjmi8 290 16 failure failure NN cord-310304-f28tjmi8 291 1 Soluble soluble JJ cord-310304-f28tjmi8 291 2 angiotensin angiotensin NN cord-310304-f28tjmi8 291 3 - - HYPH cord-310304-f28tjmi8 291 4 converting convert VBG cord-310304-f28tjmi8 291 5 enzyme enzyme NN cord-310304-f28tjmi8 291 6 2 2 CD cord-310304-f28tjmi8 291 7 : : : cord-310304-f28tjmi8 292 1 A a DT cord-310304-f28tjmi8 292 2 potential potential JJ cord-310304-f28tjmi8 292 3 approach approach NN cord-310304-f28tjmi8 292 4 for for IN cord-310304-f28tjmi8 292 5 coronavirus coronavirus NN cord-310304-f28tjmi8 292 6 infection infection NN cord-310304-f28tjmi8 292 7 therapy therapy NN cord-310304-f28tjmi8 292 8 ? ? . cord-310304-f28tjmi8 293 1 Response response NN cord-310304-f28tjmi8 293 2 to to IN cord-310304-f28tjmi8 293 3 " " `` cord-310304-f28tjmi8 293 4 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 293 5 and and CC cord-310304-f28tjmi8 293 6 ACEI ACEI NNP cord-310304-f28tjmi8 293 7 / / SYM cord-310304-f28tjmi8 293 8 ARB arb NN cord-310304-f28tjmi8 293 9 : : : cord-310304-f28tjmi8 294 1 Not not RB cord-310304-f28tjmi8 294 2 Associated associate VBN cord-310304-f28tjmi8 294 3 ? ? . cord-310304-f28tjmi8 295 1 Role role NN cord-310304-f28tjmi8 295 2 of of IN cord-310304-f28tjmi8 295 3 corticosteroid corticosteroid NN cord-310304-f28tjmi8 295 4 in in IN cord-310304-f28tjmi8 295 5 the the DT cord-310304-f28tjmi8 295 6 management management NN cord-310304-f28tjmi8 295 7 of of IN cord-310304-f28tjmi8 295 8 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 295 9 : : : cord-310304-f28tjmi8 295 10 A a DT cord-310304-f28tjmi8 295 11 systemic systemic JJ cord-310304-f28tjmi8 295 12 review review NN cord-310304-f28tjmi8 295 13 and and CC cord-310304-f28tjmi8 295 14 a a DT cord-310304-f28tjmi8 295 15 Clinician clinician NN cord-310304-f28tjmi8 295 16 's 's POS cord-310304-f28tjmi8 295 17 perspective perspective NN cord-310304-f28tjmi8 296 1 Dexamethasone dexamethasone NN cord-310304-f28tjmi8 296 2 in in IN cord-310304-f28tjmi8 296 3 Hospitalized Hospitalized NNP cord-310304-f28tjmi8 296 4 Patients Patients NNP cord-310304-f28tjmi8 296 5 with with IN cord-310304-f28tjmi8 296 6 Covid-19-Preliminary covid-19-preliminary JJ cord-310304-f28tjmi8 296 7 Report report NN cord-310304-f28tjmi8 296 8 Are be VBP cord-310304-f28tjmi8 296 9 patients patient NNS cord-310304-f28tjmi8 296 10 with with IN cord-310304-f28tjmi8 296 11 hypertension hypertension NN cord-310304-f28tjmi8 296 12 and and CC cord-310304-f28tjmi8 296 13 diabetes diabetes NN cord-310304-f28tjmi8 296 14 mellitus mellitus NN cord-310304-f28tjmi8 296 15 at at IN cord-310304-f28tjmi8 296 16 increased increase VBN cord-310304-f28tjmi8 296 17 risk risk NN cord-310304-f28tjmi8 296 18 for for IN cord-310304-f28tjmi8 296 19 COVID-19 covid-19 JJ cord-310304-f28tjmi8 296 20 infection infection NN cord-310304-f28tjmi8 296 21 ? ? . cord-310304-f28tjmi8 297 1 Renin renin NN cord-310304-f28tjmi8 297 2 - - HYPH cord-310304-f28tjmi8 297 3 Angiotensin Angiotensin NNP cord-310304-f28tjmi8 297 4 - - HYPH cord-310304-f28tjmi8 297 5 Aldosterone Aldosterone NNP cord-310304-f28tjmi8 297 6 System System NNP cord-310304-f28tjmi8 297 7 Inhibitors Inhibitors NNP cord-310304-f28tjmi8 297 8 in in IN cord-310304-f28tjmi8 297 9 Patients patient NNS cord-310304-f28tjmi8 297 10 with with IN cord-310304-f28tjmi8 297 11 Covid-19 Covid-19 NNP cord-310304-f28tjmi8 297 12 Angiotensin Angiotensin NNP cord-310304-f28tjmi8 297 13 - - HYPH cord-310304-f28tjmi8 297 14 Converting convert VBG cord-310304-f28tjmi8 297 15 Enzyme Enzyme NNP cord-310304-f28tjmi8 297 16 2 2 CD cord-310304-f28tjmi8 297 17 ( ( -LRB- cord-310304-f28tjmi8 297 18 ACE2 ACE2 NNP cord-310304-f28tjmi8 297 19 ) ) -RRB- cord-310304-f28tjmi8 297 20 Is be VBZ cord-310304-f28tjmi8 297 21 a a DT cord-310304-f28tjmi8 297 22 Key key JJ cord-310304-f28tjmi8 297 23 Modulator Modulator NNP cord-310304-f28tjmi8 297 24 of of IN cord-310304-f28tjmi8 297 25 the the DT cord-310304-f28tjmi8 297 26 Renin Renin NNP cord-310304-f28tjmi8 297 27 Angiotensin Angiotensin NNP cord-310304-f28tjmi8 297 28 System System NNP cord-310304-f28tjmi8 297 29 in in IN cord-310304-f28tjmi8 297 30 Health Health NNP cord-310304-f28tjmi8 297 31 and and CC cord-310304-f28tjmi8 297 32 Disease Disease NNP cord-310304-f28tjmi8 297 33 Angiotensin Angiotensin NNP cord-310304-f28tjmi8 297 34 - - HYPH cord-310304-f28tjmi8 297 35 converting convert VBG cord-310304-f28tjmi8 297 36 enzyme enzyme NN cord-310304-f28tjmi8 297 37 2 2 CD cord-310304-f28tjmi8 297 38 ( ( -LRB- cord-310304-f28tjmi8 297 39 ACE2 ACE2 NNP cord-310304-f28tjmi8 297 40 ) ) -RRB- cord-310304-f28tjmi8 297 41 as as IN cord-310304-f28tjmi8 297 42 a a DT cord-310304-f28tjmi8 297 43 SARS SARS NNP cord-310304-f28tjmi8 297 44 - - HYPH cord-310304-f28tjmi8 297 45 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 297 46 receptor receptor NN cord-310304-f28tjmi8 297 47 : : : cord-310304-f28tjmi8 297 48 Molecular molecular JJ cord-310304-f28tjmi8 297 49 mechanisms mechanism NNS cord-310304-f28tjmi8 297 50 and and CC cord-310304-f28tjmi8 297 51 potential potential JJ cord-310304-f28tjmi8 297 52 therapeutic therapeutic JJ cord-310304-f28tjmi8 297 53 target target NN cord-310304-f28tjmi8 297 54 Disparities disparity NNS cord-310304-f28tjmi8 297 55 in in IN cord-310304-f28tjmi8 297 56 hypertension hypertension NN cord-310304-f28tjmi8 297 57 and and CC cord-310304-f28tjmi8 297 58 cardiovascular cardiovascular JJ cord-310304-f28tjmi8 297 59 disease disease NN cord-310304-f28tjmi8 297 60 in in IN cord-310304-f28tjmi8 297 61 blacks black NNS cord-310304-f28tjmi8 297 62 : : : cord-310304-f28tjmi8 298 1 The the DT cord-310304-f28tjmi8 298 2 critical critical JJ cord-310304-f28tjmi8 298 3 role role NN cord-310304-f28tjmi8 298 4 of of IN cord-310304-f28tjmi8 298 5 medication medication NN cord-310304-f28tjmi8 298 6 adherence adherence NN cord-310304-f28tjmi8 298 7 Vital vital JJ cord-310304-f28tjmi8 298 8 Signs sign NNS cord-310304-f28tjmi8 298 9 : : : cord-310304-f28tjmi8 298 10 Disparities disparity NNS cord-310304-f28tjmi8 298 11 in in IN cord-310304-f28tjmi8 298 12 Antihypertensive Antihypertensive NNP cord-310304-f28tjmi8 298 13 Medication Medication NNP cord-310304-f28tjmi8 298 14 Nonadherence Nonadherence NNP cord-310304-f28tjmi8 299 1 Among among IN cord-310304-f28tjmi8 299 2 Medicare Medicare NNP cord-310304-f28tjmi8 299 3 Part Part NNP cord-310304-f28tjmi8 299 4 D D NNP cord-310304-f28tjmi8 299 5 Beneficiaries Beneficiaries NNP cord-310304-f28tjmi8 299 6 - - HYPH cord-310304-f28tjmi8 299 7 United United NNP cord-310304-f28tjmi8 299 8 States States NNP cord-310304-f28tjmi8 299 9 Ethnic ethnic JJ cord-310304-f28tjmi8 299 10 disparities disparity NNS cord-310304-f28tjmi8 299 11 in in IN cord-310304-f28tjmi8 299 12 adherence adherence NN cord-310304-f28tjmi8 299 13 to to IN cord-310304-f28tjmi8 299 14 antihypertensive antihypertensive JJ cord-310304-f28tjmi8 299 15 medications medication NNS cord-310304-f28tjmi8 299 16 of of IN cord-310304-f28tjmi8 299 17 medicare medicare NNP cord-310304-f28tjmi8 299 18 part part NNP cord-310304-f28tjmi8 299 19 D D NNP cord-310304-f28tjmi8 299 20 beneficiaries beneficiary NNS cord-310304-f28tjmi8 299 21 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 299 22 ) ) -RRB- cord-310304-f28tjmi8 299 23 and and CC cord-310304-f28tjmi8 299 24 Cardiovascular Cardiovascular NNP cord-310304-f28tjmi8 299 25 Disease Disease NNP cord-310304-f28tjmi8 299 26 2020 2020 CD cord-310304-f28tjmi8 299 27 Prevalence prevalence NN cord-310304-f28tjmi8 299 28 of of IN cord-310304-f28tjmi8 299 29 comorbidities comorbiditie NNS cord-310304-f28tjmi8 299 30 and and CC cord-310304-f28tjmi8 299 31 its -PRON- PRP$ cord-310304-f28tjmi8 299 32 effects effect NNS cord-310304-f28tjmi8 299 33 in in IN cord-310304-f28tjmi8 299 34 patients patient NNS cord-310304-f28tjmi8 299 35 infected infect VBN cord-310304-f28tjmi8 299 36 with with IN cord-310304-f28tjmi8 299 37 SARS SARS NNP cord-310304-f28tjmi8 299 38 - - HYPH cord-310304-f28tjmi8 299 39 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 299 40 : : : cord-310304-f28tjmi8 300 1 A a DT cord-310304-f28tjmi8 300 2 systematic systematic JJ cord-310304-f28tjmi8 300 3 review review NN cord-310304-f28tjmi8 300 4 and and CC cord-310304-f28tjmi8 300 5 meta meta NNP cord-310304-f28tjmi8 300 6 - - HYPH cord-310304-f28tjmi8 300 7 analysis analysis NN cord-310304-f28tjmi8 300 8 Clinical Clinical NNP cord-310304-f28tjmi8 300 9 Characteristics characteristic NNS cord-310304-f28tjmi8 300 10 of of IN cord-310304-f28tjmi8 300 11 138 138 CD cord-310304-f28tjmi8 300 12 Hospitalized hospitalize VBN cord-310304-f28tjmi8 300 13 Patients patient NNS cord-310304-f28tjmi8 300 14 With with IN cord-310304-f28tjmi8 300 15 2019 2019 CD cord-310304-f28tjmi8 300 16 Novel Novel NNP cord-310304-f28tjmi8 300 17 Coronavirus Coronavirus NNP cord-310304-f28tjmi8 300 18 - - HYPH cord-310304-f28tjmi8 300 19 Infected Infected NNP cord-310304-f28tjmi8 300 20 Pneumonia Pneumonia NNP cord-310304-f28tjmi8 300 21 in in IN cord-310304-f28tjmi8 300 22 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 300 23 and and CC cord-310304-f28tjmi8 300 24 the the DT cord-310304-f28tjmi8 300 25 cardiovascular cardiovascular JJ cord-310304-f28tjmi8 300 26 system system NN cord-310304-f28tjmi8 300 27 SARS SARS NNP cord-310304-f28tjmi8 300 28 - - HYPH cord-310304-f28tjmi8 300 29 coronavirus coronavirus NN cord-310304-f28tjmi8 300 30 modulation modulation NN cord-310304-f28tjmi8 300 31 of of IN cord-310304-f28tjmi8 300 32 myocardial myocardial JJ cord-310304-f28tjmi8 300 33 ACE2 ACE2 NNP cord-310304-f28tjmi8 300 34 expression expression NN cord-310304-f28tjmi8 300 35 and and CC cord-310304-f28tjmi8 300 36 inflammation inflammation NN cord-310304-f28tjmi8 300 37 in in IN cord-310304-f28tjmi8 300 38 patients patient NNS cord-310304-f28tjmi8 300 39 with with IN cord-310304-f28tjmi8 300 40 SARS SARS NNP cord-310304-f28tjmi8 300 41 Clinical Clinical NNP cord-310304-f28tjmi8 300 42 Features Features NNPS cord-310304-f28tjmi8 300 43 and and CC cord-310304-f28tjmi8 300 44 Short short JJ cord-310304-f28tjmi8 300 45 - - HYPH cord-310304-f28tjmi8 300 46 term term NN cord-310304-f28tjmi8 300 47 Outcomes outcome NNS cord-310304-f28tjmi8 300 48 of of IN cord-310304-f28tjmi8 300 49 144 144 CD cord-310304-f28tjmi8 300 50 Patients patient NNS cord-310304-f28tjmi8 300 51 With with IN cord-310304-f28tjmi8 300 52 SARS SARS NNP cord-310304-f28tjmi8 300 53 in in IN cord-310304-f28tjmi8 300 54 the the DT cord-310304-f28tjmi8 300 55 Greater Greater NNP cord-310304-f28tjmi8 300 56 Toronto Toronto NNP cord-310304-f28tjmi8 300 57 Area Area NNP cord-310304-f28tjmi8 301 1 A a DT cord-310304-f28tjmi8 301 2 current current JJ cord-310304-f28tjmi8 301 3 review review NN cord-310304-f28tjmi8 301 4 of of IN cord-310304-f28tjmi8 301 5 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 301 6 for for IN cord-310304-f28tjmi8 301 7 the the DT cord-310304-f28tjmi8 301 8 cardiovascular cardiovascular JJ cord-310304-f28tjmi8 301 9 specialist specialist NN cord-310304-f28tjmi8 301 10 Epidemiologic Epidemiologic NNP cord-310304-f28tjmi8 301 11 and and CC cord-310304-f28tjmi8 301 12 clinical clinical JJ cord-310304-f28tjmi8 301 13 characteristics characteristic NNS cord-310304-f28tjmi8 301 14 of of IN cord-310304-f28tjmi8 301 15 heart heart NN cord-310304-f28tjmi8 301 16 transplant transplant NN cord-310304-f28tjmi8 301 17 recipients recipient NNS cord-310304-f28tjmi8 301 18 during during IN cord-310304-f28tjmi8 301 19 the the DT cord-310304-f28tjmi8 301 20 2019 2019 CD cord-310304-f28tjmi8 301 21 coronavirus coronavirus NN cord-310304-f28tjmi8 301 22 outbreak outbreak NN cord-310304-f28tjmi8 301 23 in in IN cord-310304-f28tjmi8 301 24 Wuhan Wuhan NNP cord-310304-f28tjmi8 301 25 , , , cord-310304-f28tjmi8 301 26 China China NNP cord-310304-f28tjmi8 301 27 : : : cord-310304-f28tjmi8 301 28 A a DT cord-310304-f28tjmi8 301 29 descriptive descriptive JJ cord-310304-f28tjmi8 301 30 survey survey NN cord-310304-f28tjmi8 301 31 report report NN cord-310304-f28tjmi8 301 32 Guidance Guidance NNP cord-310304-f28tjmi8 301 33 for for IN cord-310304-f28tjmi8 301 34 Cardiothoracic Cardiothoracic NNP cord-310304-f28tjmi8 301 35 Transplant Transplant NNP cord-310304-f28tjmi8 301 36 and and CC cord-310304-f28tjmi8 301 37 Mechanical Mechanical NNP cord-310304-f28tjmi8 301 38 Circulatory Circulatory NNP cord-310304-f28tjmi8 301 39 Support Support NNP cord-310304-f28tjmi8 301 40 Centers Centers NNPS cord-310304-f28tjmi8 301 41 regarding regard VBG cord-310304-f28tjmi8 301 42 SARS SARS NNP cord-310304-f28tjmi8 301 43 CoV-2 CoV-2 NNP cord-310304-f28tjmi8 301 44 infection infection NN cord-310304-f28tjmi8 301 45 and and CC cord-310304-f28tjmi8 301 46 COVID-19 covid-19 JJ cord-310304-f28tjmi8 301 47 FAQs faq NNS cord-310304-f28tjmi8 301 48 for for IN cord-310304-f28tjmi8 301 49 Organ Organ NNP cord-310304-f28tjmi8 301 50 Transplantation Transplantation NNP cord-310304-f28tjmi8 302 1 The the DT cord-310304-f28tjmi8 302 2 Incubation Incubation NNP cord-310304-f28tjmi8 302 3 Period Period NNP cord-310304-f28tjmi8 302 4 of of IN cord-310304-f28tjmi8 302 5 Coronavirus Coronavirus NNP cord-310304-f28tjmi8 302 6 Disease Disease NNP cord-310304-f28tjmi8 302 7 2019 2019 CD cord-310304-f28tjmi8 302 8 ( ( -LRB- cord-310304-f28tjmi8 302 9 COVID-19 covid-19 VB cord-310304-f28tjmi8 302 10 ) ) -RRB- cord-310304-f28tjmi8 302 11 From from IN cord-310304-f28tjmi8 302 12 Publicly publicly RB cord-310304-f28tjmi8 302 13 Reported report VBN cord-310304-f28tjmi8 302 14 Confirmed confirm VBN cord-310304-f28tjmi8 302 15 Cases case NNS cord-310304-f28tjmi8 302 16 : : : cord-310304-f28tjmi8 302 17 Estimation Estimation NNP cord-310304-f28tjmi8 302 18 and and CC cord-310304-f28tjmi8 302 19 Application Application NNP cord-310304-f28tjmi8 302 20 An an DT cord-310304-f28tjmi8 302 21 Official official JJ cord-310304-f28tjmi8 302 22 American American NNP cord-310304-f28tjmi8 302 23 Thoracic Thoracic NNP cord-310304-f28tjmi8 302 24 Society Society NNP cord-310304-f28tjmi8 302 25 / / SYM cord-310304-f28tjmi8 302 26 European European NNP cord-310304-f28tjmi8 302 27 Respiratory Respiratory NNP cord-310304-f28tjmi8 302 28 Society Society NNP cord-310304-f28tjmi8 302 29 Policy Policy NNP cord-310304-f28tjmi8 302 30 Statement statement NN cord-310304-f28tjmi8 302 31 : : : cord-310304-f28tjmi8 302 32 Disparities disparity NNS cord-310304-f28tjmi8 302 33 in in IN cord-310304-f28tjmi8 302 34 Respiratory Respiratory NNP cord-310304-f28tjmi8 302 35 Health Health NNP cord-310304-f28tjmi8 302 36 Defining define VBG cord-310304-f28tjmi8 302 37 and and CC cord-310304-f28tjmi8 302 38 targeting target VBG cord-310304-f28tjmi8 302 39 health health NN cord-310304-f28tjmi8 302 40 disparities disparity NNS cord-310304-f28tjmi8 302 41 in in IN cord-310304-f28tjmi8 302 42 chronic chronic JJ cord-310304-f28tjmi8 302 43 obstructive obstructive JJ cord-310304-f28tjmi8 302 44 pulmonary pulmonary JJ cord-310304-f28tjmi8 302 45 disease disease NN cord-310304-f28tjmi8 302 46 World World NNP cord-310304-f28tjmi8 302 47 Health Health NNP cord-310304-f28tjmi8 302 48 Organization Organization NNP cord-310304-f28tjmi8 302 49 Chronic Chronic NNP cord-310304-f28tjmi8 302 50 Obstructive obstructive JJ cord-310304-f28tjmi8 302 51 Pulmonary Pulmonary NNP cord-310304-f28tjmi8 302 52 Disease Disease NNP cord-310304-f28tjmi8 302 53 Fact Fact NNP cord-310304-f28tjmi8 302 54 Sheet Sheet NNP cord-310304-f28tjmi8 302 55 World World NNP cord-310304-f28tjmi8 302 56 Health Health NNP cord-310304-f28tjmi8 302 57 Organization Organization NNP cord-310304-f28tjmi8 302 58 Commission Commission NNP cord-310304-f28tjmi8 302 59 on on IN cord-310304-f28tjmi8 302 60 Social Social NNP cord-310304-f28tjmi8 302 61 Determinants Determinants NNP cord-310304-f28tjmi8 302 62 of of IN cord-310304-f28tjmi8 302 63 Health Health NNP cord-310304-f28tjmi8 302 64 - - HYPH cord-310304-f28tjmi8 302 65 Final Final NNP cord-310304-f28tjmi8 302 66 Report Report NNP cord-310304-f28tjmi8 302 67 . . . cord-310304-f28tjmi8 303 1 Closing close VBG cord-310304-f28tjmi8 303 2 the the DT cord-310304-f28tjmi8 303 3 Gap Gap NNP cord-310304-f28tjmi8 303 4 in in IN cord-310304-f28tjmi8 303 5 a a DT cord-310304-f28tjmi8 303 6 Generation generation NN cord-310304-f28tjmi8 303 7 : : : cord-310304-f28tjmi8 303 8 Health Health NNP cord-310304-f28tjmi8 303 9 Equity Equity NNP cord-310304-f28tjmi8 303 10 Through through IN cord-310304-f28tjmi8 303 11 Action Action NNP cord-310304-f28tjmi8 303 12 on on IN cord-310304-f28tjmi8 303 13 the the DT cord-310304-f28tjmi8 303 14 Social Social NNP cord-310304-f28tjmi8 303 15 Determinants Determinants NNPS cord-310304-f28tjmi8 303 16 of of IN cord-310304-f28tjmi8 303 17 Health Health NNP cord-310304-f28tjmi8 304 1 The the DT cord-310304-f28tjmi8 304 2 impact impact NN cord-310304-f28tjmi8 304 3 of of IN cord-310304-f28tjmi8 304 4 COPD COPD NNP cord-310304-f28tjmi8 304 5 and and CC cord-310304-f28tjmi8 304 6 smoking smoke VBG cord-310304-f28tjmi8 304 7 history history NN cord-310304-f28tjmi8 304 8 on on IN cord-310304-f28tjmi8 304 9 the the DT cord-310304-f28tjmi8 304 10 severity severity NN cord-310304-f28tjmi8 304 11 of of IN cord-310304-f28tjmi8 304 12 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 304 13 : : : cord-310304-f28tjmi8 304 14 A a DT cord-310304-f28tjmi8 304 15 systemic systemic JJ cord-310304-f28tjmi8 304 16 review review NN cord-310304-f28tjmi8 304 17 and and CC cord-310304-f28tjmi8 304 18 meta meta NN cord-310304-f28tjmi8 304 19 - - HYPH cord-310304-f28tjmi8 304 20 analysis analysis NN cord-310304-f28tjmi8 304 21 Severity severity NN cord-310304-f28tjmi8 304 22 and and CC cord-310304-f28tjmi8 304 23 Mortality mortality NN cord-310304-f28tjmi8 304 24 associated associate VBN cord-310304-f28tjmi8 304 25 with with IN cord-310304-f28tjmi8 304 26 COPD COPD NNP cord-310304-f28tjmi8 304 27 and and CC cord-310304-f28tjmi8 304 28 Smoking smoking NN cord-310304-f28tjmi8 304 29 in in IN cord-310304-f28tjmi8 304 30 patients patient NNS cord-310304-f28tjmi8 304 31 with with IN cord-310304-f28tjmi8 304 32 COVID-19 covid-19 NN cord-310304-f28tjmi8 304 33 : : : cord-310304-f28tjmi8 304 34 A a DT cord-310304-f28tjmi8 304 35 Rapid Rapid NNP cord-310304-f28tjmi8 304 36 Systematic Systematic NNP cord-310304-f28tjmi8 304 37 Review Review NNP cord-310304-f28tjmi8 304 38 and and CC cord-310304-f28tjmi8 304 39 Meta Meta NNP cord-310304-f28tjmi8 304 40 - - HYPH cord-310304-f28tjmi8 304 41 Analysis Analysis NNP cord-310304-f28tjmi8 304 42 ACE-2 ACE-2 NNP cord-310304-f28tjmi8 304 43 expression expression NN cord-310304-f28tjmi8 304 44 in in IN cord-310304-f28tjmi8 304 45 the the DT cord-310304-f28tjmi8 304 46 small small JJ cord-310304-f28tjmi8 304 47 airway airway NN cord-310304-f28tjmi8 304 48 epithelia epithelium NNS cord-310304-f28tjmi8 304 49 of of IN cord-310304-f28tjmi8 304 50 smokers smoker NNS cord-310304-f28tjmi8 304 51 and and CC cord-310304-f28tjmi8 304 52 COPD COPD NNP cord-310304-f28tjmi8 304 53 patients patient NNS cord-310304-f28tjmi8 304 54 : : : cord-310304-f28tjmi8 304 55 Implications implication NNS cord-310304-f28tjmi8 304 56 for for IN cord-310304-f28tjmi8 304 57 COVID-19 covid-19 JJ cord-310304-f28tjmi8 304 58 Role Role NNP cord-310304-f28tjmi8 304 59 of of IN cord-310304-f28tjmi8 304 60 angiotensin angiotensin NN cord-310304-f28tjmi8 304 61 - - HYPH cord-310304-f28tjmi8 304 62 converting convert VBG cord-310304-f28tjmi8 304 63 enzyme enzyme NN cord-310304-f28tjmi8 304 64 ( ( -LRB- cord-310304-f28tjmi8 304 65 ACE ACE NNP cord-310304-f28tjmi8 304 66 ) ) -RRB- cord-310304-f28tjmi8 304 67 and and CC cord-310304-f28tjmi8 304 68 ACE2 ACE2 NNP cord-310304-f28tjmi8 304 69 in in IN cord-310304-f28tjmi8 304 70 a a DT cord-310304-f28tjmi8 304 71 rat rat NN cord-310304-f28tjmi8 304 72 model model NN cord-310304-f28tjmi8 304 73 of of IN cord-310304-f28tjmi8 304 74 smoke smoke NN cord-310304-f28tjmi8 304 75 inhalation inhalation NN cord-310304-f28tjmi8 304 76 induced induce VBD cord-310304-f28tjmi8 304 77 acute acute JJ cord-310304-f28tjmi8 304 78 respiratory respiratory JJ cord-310304-f28tjmi8 304 79 distress distress NN cord-310304-f28tjmi8 304 80 syndrome syndrome NN cord-310304-f28tjmi8 304 81 Ethnic ethnic JJ cord-310304-f28tjmi8 304 82 Differences difference NNS cord-310304-f28tjmi8 304 83 in in IN cord-310304-f28tjmi8 304 84 Mortality mortality NN cord-310304-f28tjmi8 304 85 , , , cord-310304-f28tjmi8 304 86 End end NN cord-310304-f28tjmi8 304 87 - - HYPH cord-310304-f28tjmi8 304 88 Stage stage NN cord-310304-f28tjmi8 304 89 Complications Complications NNPS cord-310304-f28tjmi8 304 90 , , , cord-310304-f28tjmi8 304 91 and and CC cord-310304-f28tjmi8 304 92 Quality quality NN cord-310304-f28tjmi8 304 93 of of IN cord-310304-f28tjmi8 304 94 Care Care NNP cord-310304-f28tjmi8 305 1 Among among IN cord-310304-f28tjmi8 305 2 Diabetic diabetic JJ cord-310304-f28tjmi8 305 3 Patients Patients NNPS cord-310304-f28tjmi8 305 4 : : : cord-310304-f28tjmi8 305 5 A a DT cord-310304-f28tjmi8 305 6 review review NN cord-310304-f28tjmi8 305 7 TODAY today NN cord-310304-f28tjmi8 305 8 Study Study NNP cord-310304-f28tjmi8 305 9 Group Group NNP cord-310304-f28tjmi8 305 10 . . . cord-310304-f28tjmi8 306 1 Characteristics characteristic NNS cord-310304-f28tjmi8 306 2 of of IN cord-310304-f28tjmi8 306 3 adolescents adolescent NNS cord-310304-f28tjmi8 306 4 and and CC cord-310304-f28tjmi8 306 5 youth youth NN cord-310304-f28tjmi8 306 6 with with IN cord-310304-f28tjmi8 306 7 recent recent JJ cord-310304-f28tjmi8 306 8 - - HYPH cord-310304-f28tjmi8 306 9 onset onset NN cord-310304-f28tjmi8 306 10 type type NN cord-310304-f28tjmi8 306 11 2 2 CD cord-310304-f28tjmi8 306 12 diabetes diabetes NN cord-310304-f28tjmi8 306 13 : : : cord-310304-f28tjmi8 307 1 The the DT cord-310304-f28tjmi8 307 2 TODAY today NN cord-310304-f28tjmi8 307 3 cohort cohort NN cord-310304-f28tjmi8 307 4 at at IN cord-310304-f28tjmi8 307 5 baseline baseline JJ cord-310304-f28tjmi8 307 6 Strategies strategy NNS cord-310304-f28tjmi8 307 7 for for IN cord-310304-f28tjmi8 307 8 Improving improve VBG cord-310304-f28tjmi8 307 9 Care Care NNP cord-310304-f28tjmi8 307 10 . . . cord-310304-f28tjmi8 308 1 Sec Sec NNP cord-310304-f28tjmi8 308 2 . . . cord-310304-f28tjmi8 308 3 1 1 CD cord-310304-f28tjmi8 309 1 In in IN cord-310304-f28tjmi8 309 2 Standards Standards NNPS cord-310304-f28tjmi8 309 3 of of IN cord-310304-f28tjmi8 309 4 Medical Medical NNP cord-310304-f28tjmi8 309 5 Care Care NNP cord-310304-f28tjmi8 309 6 in in IN cord-310304-f28tjmi8 309 7 Diabetes-2015 Diabetes-2015 NNP cord-310304-f28tjmi8 310 1 Racial racial JJ cord-310304-f28tjmi8 310 2 and and CC cord-310304-f28tjmi8 310 3 ethnic ethnic JJ cord-310304-f28tjmi8 310 4 differences difference NNS cord-310304-f28tjmi8 310 5 in in IN cord-310304-f28tjmi8 310 6 cardiovascular cardiovascular JJ cord-310304-f28tjmi8 310 7 disease disease NN cord-310304-f28tjmi8 310 8 risk risk NN cord-310304-f28tjmi8 310 9 factors factor NNS cord-310304-f28tjmi8 310 10 : : : cord-310304-f28tjmi8 310 11 A a DT cord-310304-f28tjmi8 310 12 systematic systematic JJ cord-310304-f28tjmi8 310 13 review review NN cord-310304-f28tjmi8 310 14 Geographic Geographic NNP cord-310304-f28tjmi8 310 15 Distribution Distribution NNP cord-310304-f28tjmi8 310 16 of of IN cord-310304-f28tjmi8 310 17 Diagnosed diagnosed JJ cord-310304-f28tjmi8 310 18 Diabetes diabetes NN cord-310304-f28tjmi8 310 19 in in IN cord-310304-f28tjmi8 310 20 the the DT cord-310304-f28tjmi8 310 21 U.S U.S NNP cord-310304-f28tjmi8 310 22 Disparities Disparities NNPS cord-310304-f28tjmi8 310 23 in in IN cord-310304-f28tjmi8 310 24 Diabetes diabetes NN cord-310304-f28tjmi8 310 25 : : : cord-310304-f28tjmi8 311 1 The the DT cord-310304-f28tjmi8 311 2 Nexus Nexus NNP cord-310304-f28tjmi8 311 3 of of IN cord-310304-f28tjmi8 311 4 Race Race NNP cord-310304-f28tjmi8 311 5 , , , cord-310304-f28tjmi8 311 6 Poverty Poverty NNP cord-310304-f28tjmi8 311 7 , , , cord-310304-f28tjmi8 311 8 and and CC cord-310304-f28tjmi8 311 9 Place Place NNP cord-310304-f28tjmi8 311 10 Health Health NNP cord-310304-f28tjmi8 311 11 Coverage Coverage NNP cord-310304-f28tjmi8 311 12 and and CC cord-310304-f28tjmi8 311 13 Care Care NNP cord-310304-f28tjmi8 311 14 in in IN cord-310304-f28tjmi8 311 15 the the DT cord-310304-f28tjmi8 311 16 South South NNP cord-310304-f28tjmi8 311 17 in in IN cord-310304-f28tjmi8 311 18 2014 2014 CD cord-310304-f28tjmi8 311 19 and and CC cord-310304-f28tjmi8 312 1 Beyond beyond IN cord-310304-f28tjmi8 312 2 Kaiser Kaiser NNP cord-310304-f28tjmi8 312 3 Family Family NNP cord-310304-f28tjmi8 312 4 Foundation Foundation NNP cord-310304-f28tjmi8 312 5 Management Management NNP cord-310304-f28tjmi8 312 6 of of IN cord-310304-f28tjmi8 312 7 Essential Essential NNP cord-310304-f28tjmi8 312 8 Hypertension Hypertension NNP cord-310304-f28tjmi8 312 9 COVID-19 COVID-19 NNP cord-310304-f28tjmi8 312 10 ) ) -RRB- cord-310304-f28tjmi8 312 11 : : : cord-310304-f28tjmi8 312 12 People People NNS cord-310304-f28tjmi8 312 13 Who who WP cord-310304-f28tjmi8 312 14 Are be VBP cord-310304-f28tjmi8 312 15 at at IN cord-310304-f28tjmi8 312 16 Higher high JJR cord-310304-f28tjmi8 312 17 Risk Risk NNP cord-310304-f28tjmi8 312 18 for for IN cord-310304-f28tjmi8 312 19 Severe Severe NNP cord-310304-f28tjmi8 312 20 Illness Illness NNP cord-310304-f28tjmi8 312 21 ; ; : cord-310304-f28tjmi8 312 22 US US NNP cord-310304-f28tjmi8 312 23 Department Department NNP cord-310304-f28tjmi8 312 24 of of IN cord-310304-f28tjmi8 312 25 Health Health NNP cord-310304-f28tjmi8 312 26 and and CC cord-310304-f28tjmi8 312 27 Human Human NNP cord-310304-f28tjmi8 312 28 Services Services NNPS cord-310304-f28tjmi8 312 29 Residual Residual NNP cord-310304-f28tjmi8 312 30 Lifetime Lifetime NNP cord-310304-f28tjmi8 312 31 Risk Risk NNP cord-310304-f28tjmi8 312 32 for for IN cord-310304-f28tjmi8 312 33 Developing develop VBG cord-310304-f28tjmi8 312 34 Hypertension hypertension NN cord-310304-f28tjmi8 312 35 in in IN cord-310304-f28tjmi8 312 36 Middle middle NN cord-310304-f28tjmi8 312 37 - - HYPH cord-310304-f28tjmi8 312 38 aged aged JJ cord-310304-f28tjmi8 312 39 Women Women NNPS cord-310304-f28tjmi8 312 40 and and CC cord-310304-f28tjmi8 312 41 Men Men NNPS cord-310304-f28tjmi8 312 42 Treatment Treatment NNP cord-310304-f28tjmi8 312 43 Options Options NNPS cord-310304-f28tjmi8 312 44 for for IN cord-310304-f28tjmi8 312 45 COVID-19 covid-19 NN cord-310304-f28tjmi8 312 46 : : : cord-310304-f28tjmi8 313 1 The the DT cord-310304-f28tjmi8 313 2 Reality Reality NNP cord-310304-f28tjmi8 313 3 and and CC cord-310304-f28tjmi8 313 4 Challenges Challenges NNPS cord-310304-f28tjmi8 313 5 Review Review NNP cord-310304-f28tjmi8 313 6 Potential potential JJ cord-310304-f28tjmi8 313 7 Antiviral antiviral JJ cord-310304-f28tjmi8 313 8 Drugs drug NNS cord-310304-f28tjmi8 313 9 for for IN cord-310304-f28tjmi8 313 10 SARS SARS NNP cord-310304-f28tjmi8 313 11 - - HYPH cord-310304-f28tjmi8 313 12 Cov-2 Cov-2 NNP cord-310304-f28tjmi8 313 13 Treatment treatment NN cord-310304-f28tjmi8 313 14 : : : cord-310304-f28tjmi8 314 1 Preclinical Preclinical NNP cord-310304-f28tjmi8 314 2 Findings Findings NNPS cord-310304-f28tjmi8 314 3 and and CC cord-310304-f28tjmi8 314 4 Ongoing Ongoing NNP cord-310304-f28tjmi8 314 5 Clinical Clinical NNP cord-310304-f28tjmi8 314 6 Research Research NNP cord-310304-f28tjmi8 314 7 Higginson Higginson NNP cord-310304-f28tjmi8 314 8 , , , cord-310304-f28tjmi8 314 9 I. I. NNP cord-310304-f28tjmi8 314 10 Palliative Palliative NNP cord-310304-f28tjmi8 314 11 care care NN cord-310304-f28tjmi8 314 12 and and CC cord-310304-f28tjmi8 314 13 management management NN cord-310304-f28tjmi8 314 14 of of IN cord-310304-f28tjmi8 314 15 troublesome troublesome JJ cord-310304-f28tjmi8 314 16 symptoms symptom NNS cord-310304-f28tjmi8 314 17 for for IN cord-310304-f28tjmi8 314 18 people people NNS cord-310304-f28tjmi8 314 19 with with IN cord-310304-f28tjmi8 314 20 chronic chronic JJ cord-310304-f28tjmi8 314 21 obstructive obstructive JJ cord-310304-f28tjmi8 314 22 pulmonary pulmonary JJ cord-310304-f28tjmi8 314 23 disease disease NN cord-310304-f28tjmi8 315 1 This this DT cord-310304-f28tjmi8 315 2 article article NN cord-310304-f28tjmi8 315 3 is be VBZ cord-310304-f28tjmi8 315 4 an an DT cord-310304-f28tjmi8 315 5 open open JJ cord-310304-f28tjmi8 315 6 access access NN cord-310304-f28tjmi8 315 7 article article NN cord-310304-f28tjmi8 315 8 distributed distribute VBN cord-310304-f28tjmi8 315 9 under under IN cord-310304-f28tjmi8 315 10 the the DT cord-310304-f28tjmi8 315 11 terms term NNS cord-310304-f28tjmi8 315 12 and and CC cord-310304-f28tjmi8 315 13 conditions condition NNS cord-310304-f28tjmi8 315 14 of of IN cord-310304-f28tjmi8 315 15 the the DT cord-310304-f28tjmi8 315 16 Creative Creative NNP cord-310304-f28tjmi8 315 17 Commons Commons NNP cord-310304-f28tjmi8 315 18 Attribution Attribution NNP cord-310304-f28tjmi8 315 19 ( ( -LRB- cord-310304-f28tjmi8 315 20 CC CC NNP cord-310304-f28tjmi8 315 21 BY by IN cord-310304-f28tjmi8 315 22 ) ) -RRB- cord-310304-f28tjmi8 315 23 license license NN