id author title date pages extension mime words sentences flesch summary cache txt cord-273351-vq3budip Farré, Núria Prolonged QT Interval in SARS-CoV-2 Infection: Prevalence and Prognosis 2020-08-21 .txt text/plain 4368 238 51 A prolonged QTc was independently associated with a higher mortality even after adjustment for age, comorbidities, and treatment with hydroxychloroquine and azithromycin. QTc prolongation was defined as an increase of at least one millisecond in QTc compared to baseline QTc. According to the protocol at our center at the time of the study, treatment with hydroxychloroquine and azithromycin was recommended to all patients. The variables included in the model were age, baseline QTc > 480 ms, chronic kidney disease, treatment with azithromycin and hydroxychloroquine, ischemic chronic disease, atrial fibrillation or flutter, heart failure, and the presence of any cardiovascular risk factor. Although these differences could be due to a more severe presentation in a group of elderly comorbid patients, SARS-CoV-2 infection could be the cause of this prolonged QTc interval, either as a direct effect of the virus or through systemic inflammation. A prolonged QTc was independently associated with a higher risk of mortality even after adjustment for age, comorbidities, and treatment with hydroxychloroquine and azithromycin. ./cache/cord-273351-vq3budip.txt ./txt/cord-273351-vq3budip.txt