id author title date pages extension mime words sentences flesch summary cache txt cord-252687-7084pfqm Szelenberger, Rafal Ischemic Stroke among the Symptoms Caused by the COVID-19 Infection 2020-08-19 .txt text/plain 7334 378 37 Many clinical studies have shown an association between SARS-CoV-2 infection and hypercoagulability diagnosed on the basis of abnormal coagulation parameters, including activated partial thromboplastin time, prothrombin time, fibrinogen, D-dimer and C-reactive protein level. In this review, the potential mechanism and the effect of the SARS-CoV-2 viral infection on the development of ischemic stroke in COVID-19 patients were carefully studied. study, in which most non-survivor COVID-19 patients' (71.4%) blood tests showed prolonged prothrombin time and an increased D-dimer levels, which indicated the state after activation of the plasma coagulation system [14] . The accumulation of immune cells in the vascular wall in response to the viral infection, especially among patients with ischemic risk factors, induces endothelial dysfunction, migration and proliferation of cells, activation of coagulation cascade and production of fibrous plaques. ./cache/cord-252687-7084pfqm.txt ./txt/cord-252687-7084pfqm.txt