id author title date pages extension mime words sentences flesch summary cache txt cord-285691-pceenwb6 Falo, Louis D. Advances in skin science enable the development of a COVID-19 Vaccine 2020-05-30 .txt text/plain 180 17 37 key: cord-285691-pceenwb6 title: Advances in skin science enable the development of a COVID-19 Vaccine cord_uid: pceenwb6 expressing adenovectors and adjuvant in the same MNAs resulting in a vaccine that induced both antibody responses and enhanced cytotoxic cellular immunity that is likely important for "universal" vaccines and cancer immunotherapies. Taken together, these and studies by others demonstrate the potential for the development of cutaneous immune engineering strategies to control systemic immune responses including the potential for developing novel vaccine strategies and immunotherapies, and even negative immunization strategies to treat systemic allergy and autoimmune diseases. Advances in skin biology are making important contributions to the fight against the COVID-19 pandemic demonstrating once again that dermatology is more than skin deep. Microneedles for drug and vaccine delivery Microneedle array delivered recombinant coronavirus vaccines: Immunogenicity and rapid translational development Improved cutaneous genetic immunization by microneedle array delivery of an adjuvanted adenovirus vaccine ./cache/cord-285691-pceenwb6.txt ./txt/cord-285691-pceenwb6.txt