id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-338576-gh1plurq	Regen, Francesca	A Simple Approach to Optimum Pool Size for Pooled SARS-CoV-2 Testing	2020-08-28		.txt	text/plain	1201	69	54	Finally, we derive a simple-to-use formula and table that allows laboratories performing sample pooling to assess the optimum pool size at a presently experienced target prevalence rate. table that allows laboratories performing sample pooling to assess the optimum pool size at a presently experienced target prevalence rate. Here we provide a simple strategy to estimate the optimum pool size for a two-staged pooling based on a known target prevalence. The optimum pool size for a given frequency is defined by the local minima of the isolines in figure 1A and can be more precisely determined by the first derivative of equation 1 Results from our analysis clearly demonstrate the relation between target prevalence rates and optimum pool sizes in a two staged pooling strategy. The relation between the estimated analyses per specimen and a pool size are given for various target prevalence rates as defined by equation 1 (isolines; A). Local minima suggest optimum pool sizes at the respective target prevalence rate (isolines; A).	./cache/cord-338576-gh1plurq.txt	./txt/cord-338576-gh1plurq.txt