id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-286743-z0e5arlm	Langer-Gould, Annette	Early Identification of COVID-19 Cytokine Storm and Treatment with Anakinra or Tocilizumab	2020-08-06		.txt	text/plain	4258	213	43	Subsequently, a shift in practice by clinicians at some of our medical centers aimed to identify early COVID19-CS through laboratory abnormalities in patients with increasing O2 requirements and to initiate combined treatment with anakinra and corticosteroids occurred. Data were extracted by manual reviewing the EHR, including onset of dyspnea and other COVID-19 symptoms, age, sex, comorbidities, smoking status, tocilizumab and anakinra use, other J o u r n a l P r e -p r o o f treatments rendered for hydroxychloroquine, and/or corticosteroids) , fever (>100.4F), hypotension requiring pressors, dates of admission, intubation, extubation, discharge and/or death. The primary purpose of analyses was to describe clinical outcomes among tocilizumab-or anakinra-treated COVID-19 patients and to examine whether differences in outcomes could be accounted for by COVID19-CS severity and/or duration at the time of treatment initiation (baseline).	./cache/cord-286743-z0e5arlm.txt	./txt/cord-286743-z0e5arlm.txt