id author title date pages extension mime words sentences flesch summary cache txt cord-024631-yvek5vjz Althaus, T. Causes of fever in primary care in Southeast Asia and the performance of C-reactive protein in discriminating bacterial from viral pathogens 2020-05-11 .txt text/plain 4327 226 43 OBJECTIVES: We investigated causes of fever in the primary levels of care in Southeast Asia, and evaluated whether C-reactive protein (CRP) could distinguish bacterial from viral pathogens. In this study, we aim to identify key organisms among acutely febrile children and adults attending primary health care in Southeast Asia, and to evaluate the performance of CRP for discriminating between bacteria and viruses. Specimens were collected from febrile patients recruited into a previously described multi-centre randomised-controlled trial evaluating the impact of C-reactive protein (CRP) testing on antibiotic prescription in primary care [38] . We investigated the spectrum of organisms among febrile children and adults in the community and evaluated the performance of CRP in distinguishing bacteria from viruses including its potential impact on antibiotic prescription compared with current practice. Investigating non-malarial acute febrile illness remains challenging in resource-poor areas [8] , and despite screening for multiple organisms on blood and respiratory specimens, we were only able to identify a probable cause of fever in 227 (29.4%) of patients. ./cache/cord-024631-yvek5vjz.txt ./txt/cord-024631-yvek5vjz.txt