id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-269644-94yrkzns	Cousin, Mathias	Rhinovirus‐associated pulmonary exacerbations show a lack of FEV (1) improvement in children with cystic fibrosis	2016-01-29		.txt	text/plain	2037	111	46	BACKGROUND: Respiratory viral infections lead to bronchial inflammation in patients with cystic fibrosis, especially during pulmonary exacerbations. The aim of this study was to determine the impact of viral‐associated pulmonary exacerbations in children with cystic fibrosis and failure to improve forced expiratory volume in 1 s (FEV (1)) after an appropriate treatment. CONCLUSIONS: Rhinovirus infection seems to play a role in the FEV (1) recovery after pulmonary exacerbation treatment in children with cystic fibrosis. The only risk factor significantly associated with failure to improve FEV 1 above 5% after PEx was viral respiratory infection at V2 and/or V3 (OR, 2Á04; 95% CI, 1Á57-2Á67) P = 0Á0088 and especially with rhinovirus infection: (OR, 12; 95% CI, 1Á29-111Á32, P = 0Á0288). The results of this pilot study show that rhinovirus infection during PEx is significantly associated with failure to improve FEV 1 after PEx treatment in children with CF. Incidence and risk factors for pulmonary exacerbation treatment failures in patients with cystic fibrosis chronically infected with Pseudomonas aeruginosa	./cache/cord-269644-94yrkzns.txt	./txt/cord-269644-94yrkzns.txt