id author title date pages extension mime words sentences flesch summary cache txt cord-283623-umqu07te Ponce-Alonso, Manuel Impact of the coronavirus disease 2019 (COVID-19) pandemic on nosocomial Clostridioides difficile infection 2020-09-08 .txt text/plain 3228 137 40 METHODS: We retrospectively compared the incidence density (cases per 10,000 patient days) of healthcare-facility–associated (HCFA) CDI in a tertiary-care hospital in Madrid, Spain, during the maximum incidence of COVID-19 (March 11 to May 11, 2020) with the same period of the previous year (control period). CONCLUSIONS: The observed reduction of ~70% in the incidence density of HCFA CDI in a context of no reduction in antibiotic use supports the importance of reducing nosocomial transmission by healthcare workers and asymptomatic colonized patients, reinforcing cleaning procedures and reducing patient mobility in the epidemiological control of CDI. Despite the aforementioned limitations, our observation of a dramatic decrease in CDI in a context of no reduction in the use of antibiotics supports the importance of reducing the nosocomial transmission by healthcare workers or asymptomatically colonized patients, reinforcing cleaning procedure and reducing hospital mobility of patients in the epidemiological control of CDI. ./cache/cord-283623-umqu07te.txt ./txt/cord-283623-umqu07te.txt