id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-269353-wgeuh1i2	Tian, Lin	The adaptation of codon usage of +ssRNA viruses to their hosts	2018-06-02		.txt	text/plain	2573	163	61	Consequently, we test the hypothesis that similarity of codon usage preference and the degree of matching between BSTVs and their hosts will be lower than that of NSTVs, which only need to coevolve with few hosts. Our results show that NSTVs have a higher degree of matching to their hosts' tRNA pools than BSTVs. Further, analysis of the effective number of codons (ENC) infers that codon usage bias of NSTVs is relatively stronger than that of BSTVs. Thus, codon usage of NSTVs tends to better match their host than that of BSTVs. This supports the hypothesis that viruses adapt to the expression system of their host(s). As expected, our analysis show that generally NSTVs are more adapted to their hosts' codon usage pattern and tRNA pools than BSTVs. This may help the virus to use the host transcript machinery more efficiently and, therefore, replicate faster.	./cache/cord-269353-wgeuh1i2.txt	./txt/cord-269353-wgeuh1i2.txt