id author title date pages extension mime words sentences flesch summary cache txt cord-267168-qjktnnn6 Wille, Michelle Evolutionary genetics of canine respiratory coronavirus and recent introduction into Swedish dogs 2020-03-20 .txt text/plain 6275 349 56 In this study, Swedish privately-owned dogs with characteristic signs of canine infectious respiratory disease (n = 88) were screened for CRCoV and 13 positive samples (14.7%, 8.4–23.7% [95% confidence interval (CI)]) were further sequenced. To assess recombination, a concatenated sequence was generated including the viruses from which there were sequences from the partial Non-structural protein 2a (NS), and full length HE, S, envelope (E), and M, resulting in 6541 bp for analysis and the genes were placed in genomic order. Assessment of the S, E, M, NS2 and HE genes generated using Sanger and high-throughput sequencing (Table A1 ) demonstrated high genetic similarity of viruses detected in Swedish dogs, despite sampling from numerous clinics across Sweden and an over a period of 3 years. In this study, we aimed to reveal the epidemiology and evolutionary genetics of CRCoV, one of the causative agents of canine infectious respiratory disease (CIRD), in Sweden. ./cache/cord-267168-qjktnnn6.txt ./txt/cord-267168-qjktnnn6.txt