id author title date pages extension mime words sentences flesch summary cache txt cord-337889-90q4py0j Guan, Wei-jie Comorbidity and its impact on 1590 patients with Covid-19 in China: A Nationwide Analysis 2020-03-26 .txt text/plain 4718 204 39 After adjusting for age and smoking status, COPD [hazards ratio (HR) 2.681, 95% confidence interval (95%CI) 1.424–5.048], diabetes (HR 1.59, 95%CI 1.03–2.45), hypertension (HR 1.58, 95%CI 1.07–2.32) and malignancy (HR 3.50, 95%CI 1.60–7.64) were risk factors of reaching to the composite endpoints. Studies that address these limitations is needed to explore for the factors underlying the adverse impact of Our objective was to evaluate the risk of serious adverse outcomes in patients with Covid-19 by stratification according to the number and type of comorbidities, thus unraveling the sub-populations with poorer prognosis. These findings have provided further objective evidence, with a large sample size and extensive coverage of the geographic regions across China, to take into account baseline comorbid diseases in the comprehensive risk assessment of prognosis among patients with Covid-19 on hospital admission. Our findings suggested that, similar with other severe acute respiratory outbreaks, comorbidities such as COPD, diabetes, hypertension and malignancy predisposed to adverse clinical outcomes in patients with Covid-19. ./cache/cord-337889-90q4py0j.txt ./txt/cord-337889-90q4py0j.txt